Overview

ID MAG02377
Name MMD2_bin.9
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Patescibacteriota
Class Minisyncoccia
Order Minisyncoccales
Family JAHCRE01
Genus
Species
Assembly information
Completeness (%) 97.72
Contamination (%) 1.27
GC content (%) 35.0
N50 (bp) 5,521
Genome size (bp) 670,685

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes629

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1018508_0 HAD hydrolase, family IA, variant - - - 0.00000000000000000000001817 108.0
MMD2_k127_1018508_1 COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.00000001835 55.0
MMD2_k127_1071816_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000003774 207.0
MMD2_k127_1071816_1 GTP-binding protein LepA C-terminus K03596 - - 0.00000000001485 65.0
MMD2_k127_1071816_3 septum formation initiator K05589 - - 0.00007521 51.0
MMD2_k127_1140859_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1193.0
MMD2_k127_1140859_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.071e-221 700.0
MMD2_k127_1155022_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 323.0
MMD2_k127_1155022_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000001319 66.0
MMD2_k127_1170689_0 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 416.0
MMD2_k127_1170689_1 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 374.0
MMD2_k127_1170689_10 Prokaryotic N-terminal methylation motif K02650 - - 0.000002187 55.0
MMD2_k127_1170689_11 Pilus assembly protein, PilO K02664 - - 0.0002199 50.0
MMD2_k127_1170689_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 344.0
MMD2_k127_1170689_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 315.0
MMD2_k127_1170689_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001788 282.0
MMD2_k127_1170689_5 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000004014 254.0
MMD2_k127_1170689_6 ComF family K02242 - - 0.000000000000000000000000000000000001657 147.0
MMD2_k127_1170689_7 ATP-dependent DNA helicase activity K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.00000000000000000000000000000005967 132.0
MMD2_k127_1170689_8 Type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000163 119.0
MMD2_k127_1170689_9 response regulator K07664 - - 0.000000000000001183 81.0
MMD2_k127_1198203_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004228 230.0
MMD2_k127_1198203_1 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.0000000000000000000000000000000000000000000000899 174.0
MMD2_k127_1198203_2 mRNA catabolic process K06950 - - 0.0000000000000000000000000000000000002433 148.0
MMD2_k127_1200951_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K07137 - - 3.175e-227 711.0
MMD2_k127_1200951_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 535.0
MMD2_k127_1200951_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000001173 130.0
MMD2_k127_1200951_3 bacitracin transport permease K19302 - 3.6.1.27 0.00000000000000000001114 98.0
MMD2_k127_1200951_4 Site-specific recombinase, DNA invertase Pin - - - 0.000392 44.0
MMD2_k127_121226_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 538.0
MMD2_k127_121226_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 466.0
MMD2_k127_121226_10 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000973 53.0
MMD2_k127_121226_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 421.0
MMD2_k127_121226_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 342.0
MMD2_k127_121226_4 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 332.0
MMD2_k127_121226_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003686 268.0
MMD2_k127_121226_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000004796 150.0
MMD2_k127_121226_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000009188 129.0
MMD2_k127_121226_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002992 79.0
MMD2_k127_121226_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000636 66.0
MMD2_k127_122903_0 Yip1 domain - - - 0.00000000003138 72.0
MMD2_k127_1246476_0 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000001358 231.0
MMD2_k127_1246476_1 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000001126 72.0
MMD2_k127_1246476_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000001517 67.0
MMD2_k127_1246476_3 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000008236 63.0
MMD2_k127_127297_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 331.0
MMD2_k127_127297_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000001276 167.0
MMD2_k127_136317_0 Iron only hydrogenase large subunit, C-terminal domain K00336,K18332 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 411.0
MMD2_k127_136317_1 domain protein K02238 - - 0.00000000000000000000000000000000000000000000000000000001307 207.0
MMD2_k127_136317_2 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000001723 132.0
MMD2_k127_136317_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000001134 76.0
MMD2_k127_1375170_0 Negative regulator of - - - 0.00001708 52.0
MMD2_k127_138536_0 Penicillin-binding Protein K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 307.0
MMD2_k127_138536_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000437 142.0
MMD2_k127_138536_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000006857 53.0
MMD2_k127_141790_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000005824 220.0
MMD2_k127_141790_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000005805 122.0
MMD2_k127_1434671_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002119 212.0
MMD2_k127_1434671_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000002563 189.0
MMD2_k127_1434671_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000002432 131.0
MMD2_k127_1434671_3 Methyltransferase domain - - - 0.000000002025 60.0
MMD2_k127_1542013_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000002021 246.0
MMD2_k127_1542013_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000001236 174.0
MMD2_k127_1730872_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 1.59e-276 867.0
MMD2_k127_1805774_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 496.0
MMD2_k127_1805774_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000007377 106.0
MMD2_k127_1805774_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000001738 62.0
MMD2_k127_1805774_3 Domain of unknown function DUF11 - - - 0.0001643 54.0
MMD2_k127_1812208_0 CYTH domain K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000001193 180.0
MMD2_k127_1812208_1 - - - - 0.0000000000000000007736 92.0
MMD2_k127_1812208_2 NUDIX domain - - - 0.0000004367 57.0
MMD2_k127_183317_0 Dihydroxyacetone kinase family - - - 0.000000000000000000000000000000000006509 147.0
MMD2_k127_183317_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000002829 117.0
MMD2_k127_183317_2 DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000000000000004387 114.0
MMD2_k127_1851216_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000002853 172.0
MMD2_k127_1851216_1 Zincin-like metallopeptidase - - - 0.00000000000000000000000000005385 120.0
MMD2_k127_1851216_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000129 108.0
MMD2_k127_1851216_3 PFAM membrane-flanked domain - - - 0.0003029 50.0
MMD2_k127_194014_0 DNA-directed DNA polymerase activity K02337 - 2.7.7.7 4.939e-279 881.0
MMD2_k127_194014_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000004159 200.0
MMD2_k127_194014_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000003846 183.0
MMD2_k127_194014_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000002026 123.0
MMD2_k127_194014_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000003315 72.0
MMD2_k127_194014_5 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000005058 66.0
MMD2_k127_2027218_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000005326 266.0
MMD2_k127_2027218_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000003704 190.0
MMD2_k127_2027218_2 Alpha/beta hydrolase family - - - 0.00002439 47.0
MMD2_k127_2033989_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
MMD2_k127_2033989_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001602 265.0
MMD2_k127_2033989_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000003606 151.0
MMD2_k127_2033989_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.00000000000006281 72.0
MMD2_k127_2049035_0 ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000001905 186.0
MMD2_k127_2049035_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000006614 59.0
MMD2_k127_2178322_0 DNA polymerase X family K02347 - - 5.97e-246 771.0
MMD2_k127_2178322_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006648 277.0
MMD2_k127_2178322_10 Transcription elongation factor, N-terminal K03624 - - 0.00000000000000000006315 94.0
MMD2_k127_2178322_11 Metal dependent phosphohydrolase K07023 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0016787,GO:0016788,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - 0.00000000000000000504 97.0
MMD2_k127_2178322_12 - - - - 0.000000000000000075 84.0
MMD2_k127_2178322_13 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000004533 79.0
MMD2_k127_2178322_14 Methyltransferase K00567,K10778,K13531 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.0000000000006812 72.0
MMD2_k127_2178322_15 Acetyltransferase (GNAT) domain - - - 0.00000001312 62.0
MMD2_k127_2178322_16 Major Facilitator K08161 - - 0.0000000171 63.0
MMD2_k127_2178322_17 PFAM conserved K07027 - - 0.000005157 58.0
MMD2_k127_2178322_18 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00009822 47.0
MMD2_k127_2178322_2 Desulfoferrodoxin, ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000002207 196.0
MMD2_k127_2178322_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000799 145.0
MMD2_k127_2178322_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000006837 143.0
MMD2_k127_2178322_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000005099 134.0
MMD2_k127_2178322_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000001646 126.0
MMD2_k127_2178322_7 NUDIX domain - - - 0.0000000000000000000000000000001968 128.0
MMD2_k127_2178322_8 Belongs to the peptidase S11 family K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.0000000000000000000000004177 120.0
MMD2_k127_2178322_9 HD domain-containing protein 2 K07023 GO:0008150,GO:0030431,GO:0032501 - 0.0000000000000000000152 105.0
MMD2_k127_2185879_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.494e-290 907.0
MMD2_k127_2185879_1 iron hydrogenase, small subunit K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000546 239.0
MMD2_k127_2185879_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000852 210.0
MMD2_k127_2185879_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000003881 196.0
MMD2_k127_2185879_4 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000383 144.0
MMD2_k127_2185879_5 - - - - 0.00000000000000000000000000000001205 132.0
MMD2_k127_2185879_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.0000000000328 64.0
MMD2_k127_2248677_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000294 118.0
MMD2_k127_2248677_1 peptidase activity K20333 - - 0.00000000000000001801 93.0
MMD2_k127_2248677_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000178 89.0
MMD2_k127_2404719_0 Alternative locus ID - - - 0.0000000000000000000000000000000000001597 149.0
MMD2_k127_2404719_1 Psort location CytoplasmicMembrane, score K08978 - - 0.0000000000000000000000000000005391 126.0
MMD2_k127_2404719_2 Predicted membrane protein (DUF2207) - - - 0.00000006016 57.0
MMD2_k127_2404719_3 NUDIX domain K03574 - 3.6.1.55 0.0002356 43.0
MMD2_k127_242247_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 454.0
MMD2_k127_242247_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000003728 228.0
MMD2_k127_242247_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000001005 145.0
MMD2_k127_242247_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000181 140.0
MMD2_k127_242247_4 PFAM Adenylate cyclase K05873 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 4.6.1.1 0.0000001062 60.0
MMD2_k127_2438297_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000001093 115.0
MMD2_k127_2438297_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000001953 112.0
MMD2_k127_2448563_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000007279 90.0
MMD2_k127_2448563_1 Putative ATP-dependent DNA helicase recG C-terminal K02444,K03655 - 3.6.4.12 0.0001677 48.0
MMD2_k127_2456888_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 8.424e-280 876.0
MMD2_k127_2456888_1 transcription-coupled nucleotide-excision repair, DNA damage recognition K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 554.0
MMD2_k127_2456888_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000002514 158.0
MMD2_k127_2456888_11 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000002957 149.0
MMD2_k127_2456888_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000005928 153.0
MMD2_k127_2456888_13 GatB Yqey domain protein K09117 - - 0.000000000000000000000000000000000288 137.0
MMD2_k127_2456888_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000009533 97.0
MMD2_k127_2456888_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 372.0
MMD2_k127_2456888_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 364.0
MMD2_k127_2456888_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 288.0
MMD2_k127_2456888_6 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000004484 242.0
MMD2_k127_2456888_7 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000005975 235.0
MMD2_k127_2456888_8 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000000000000000000000000000004125 224.0
MMD2_k127_2456888_9 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000001926 173.0
MMD2_k127_251172_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K01535,K16905 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 6.658e-267 846.0
MMD2_k127_251172_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 450.0
MMD2_k127_251172_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000006182 162.0
MMD2_k127_251172_3 transcriptional regulator - - - 0.00000000000000000000001553 104.0
MMD2_k127_2542024_0 Signal peptidase K13280 - 3.4.21.89 0.0000004459 59.0
MMD2_k127_2542024_1 - - - - 0.0000007219 55.0
MMD2_k127_2589982_0 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000001377 128.0
MMD2_k127_2589982_1 Belongs to the ComB family K05979 - 3.1.3.71 0.000001348 59.0
MMD2_k127_2589982_2 Acetyltransferase (GNAT) domain - - - 0.000004012 53.0
MMD2_k127_2625075_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000004483 248.0
MMD2_k127_2625075_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000006858 134.0
MMD2_k127_2675419_0 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 323.0
MMD2_k127_2675419_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000005064 62.0
MMD2_k127_2720241_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001572 248.0
MMD2_k127_2720241_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001228 188.0
MMD2_k127_2720241_2 Bacterial protein of unknown function (DUF916) - - - 0.000000000000000000000003774 116.0
MMD2_k127_2720241_3 Belongs to the peptidase S8 family - - - 0.00000003639 65.0
MMD2_k127_2724109_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.994e-227 719.0
MMD2_k127_2724109_1 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 505.0
MMD2_k127_2724109_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 328.0
MMD2_k127_2724109_3 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.00000000000004579 76.0
MMD2_k127_2724109_4 inorganic pyrophosphatase K15986 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 0.0001209 45.0
MMD2_k127_2724109_5 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0001475 44.0
MMD2_k127_2741701_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 425.0
MMD2_k127_2870681_1 - - - - 0.000000000006282 67.0
MMD2_k127_2870681_2 - - - - 0.0002478 46.0
MMD2_k127_28743_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000002639 236.0
MMD2_k127_28743_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000229 164.0
MMD2_k127_28743_2 GrpB protein - - - 0.0000000000000000000000000000000000000000002122 164.0
MMD2_k127_28743_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000004979 95.0
MMD2_k127_2967184_0 Belongs to the DegT DnrJ EryC1 family K18653 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000002206 265.0
MMD2_k127_2967184_1 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 262.0
MMD2_k127_2967184_2 transketolase activity K00615 - 2.2.1.1 0.00000000000000000000000000000000003705 139.0
MMD2_k127_2967184_3 Bacterial sugar transferase K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000007832 84.0
MMD2_k127_2967184_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000004013 72.0
MMD2_k127_2967184_5 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 0.000000000006596 71.0
MMD2_k127_3034491_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 260.0
MMD2_k127_3034491_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000001343 227.0
MMD2_k127_3034491_2 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000002639 227.0
MMD2_k127_3034491_3 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000001014 186.0
MMD2_k127_3034491_4 HlyD membrane-fusion protein of T1SS K02005 - - 0.0000000000000000001767 102.0
MMD2_k127_3034491_5 Ribosomal protein L33 K02913 - - 0.0000000426 57.0
MMD2_k127_3034491_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.0007259 45.0
MMD2_k127_3040800_0 Peptidase M30 - - - 0.0000002461 63.0
MMD2_k127_3097167_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000001956 156.0
MMD2_k127_3097167_2 - - - - 0.00000000000000004358 84.0
MMD2_k127_3145610_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 523.0
MMD2_k127_3145610_1 Lysin motif - - - 0.00000000000000000000001141 113.0
MMD2_k127_314687_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 454.0
MMD2_k127_314687_1 nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000003781 185.0
MMD2_k127_314687_2 Methyltransferase domain K10770 - 2.1.1.229 0.0000001041 60.0
MMD2_k127_3166539_0 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000006483 149.0
MMD2_k127_321841_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 385.0
MMD2_k127_321841_1 type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 357.0
MMD2_k127_321841_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 281.0
MMD2_k127_321841_3 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000332 173.0
MMD2_k127_321841_4 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000001115 160.0
MMD2_k127_321841_5 - - - - 0.0000000000000000000000000000000000048 145.0
MMD2_k127_321841_6 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000002987 106.0
MMD2_k127_321841_7 tRNA threonylcarbamoyladenosine modification K06925,K07102 - 2.7.1.221 0.00000000000000000002953 96.0
MMD2_k127_321841_8 cellulose binding - - - 0.0000006502 61.0
MMD2_k127_3232939_0 Membrane bound O-acyl transferase, MBOAT family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007227 286.0
MMD2_k127_3232939_1 protein conserved in bacteria K09795 - - 0.0000000000000000000000000000000003218 145.0
MMD2_k127_3313540_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 332.0
MMD2_k127_3313540_1 Bacterial sugar transferase K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004592 282.0
MMD2_k127_3313540_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 245.0
MMD2_k127_3313540_3 Bacterial sugar transferase K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000007946 222.0
MMD2_k127_3313540_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000005369 212.0
MMD2_k127_3313540_5 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000000000000000000000000002005 153.0
MMD2_k127_3313540_6 Phosphopantetheine attachment site - - - 0.000000001629 67.0
MMD2_k127_3320819_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000001922 177.0
MMD2_k127_3347026_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.426e-252 803.0
MMD2_k127_3347026_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 468.0
MMD2_k127_3347026_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000003799 198.0
MMD2_k127_3347026_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000003986 184.0
MMD2_k127_3347026_4 PFAM Methyltransferase - - - 0.00000000005644 70.0
MMD2_k127_337196_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 454.0
MMD2_k127_337196_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000001347 226.0
MMD2_k127_337196_2 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000136 213.0
MMD2_k127_337196_3 PFAM Histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000000000001909 219.0
MMD2_k127_337196_4 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.0000000000000000000003958 102.0
MMD2_k127_3372154_0 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000005408 139.0
MMD2_k127_3372154_1 nitroreductase - - - 0.0000000000000000744 85.0
MMD2_k127_3389975_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 478.0
MMD2_k127_3389975_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000001961 194.0
MMD2_k127_3424873_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000001312 211.0
MMD2_k127_3424873_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000002671 161.0
MMD2_k127_3424873_2 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000279 113.0
MMD2_k127_3432481_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 589.0
MMD2_k127_3432481_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 357.0
MMD2_k127_3432481_2 photoreceptor activity K15850 - 2.7.13.3 0.0000000000000000000000000000001866 139.0
MMD2_k127_3432481_3 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000008983 88.0
MMD2_k127_3432481_4 Protein of unknown function (DUF2961) K14109 - - 0.0000000229 60.0
MMD2_k127_3432481_5 - - - - 0.000008414 57.0
MMD2_k127_3432481_6 Bacterial PH domain K08981 - - 0.0001177 51.0
MMD2_k127_3449020_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
MMD2_k127_3449020_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 381.0
MMD2_k127_3449020_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000007406 111.0
MMD2_k127_3449020_11 PFAM response regulator receiver - - - 0.0000000000000000000001121 102.0
MMD2_k127_3449020_12 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000004358 107.0
MMD2_k127_3449020_13 Glycosyl transferase 4-like domain - - - 0.000000000000000002885 92.0
MMD2_k127_3449020_14 Pilus assembly protein K02662 - - 0.00000000000000001754 94.0
MMD2_k127_3449020_15 lipid binding - - - 0.0000000000005042 76.0
MMD2_k127_3449020_16 Transcription factor zinc-finger K09981 - - 0.0000000000005587 76.0
MMD2_k127_3449020_17 protein transport across the cell outer membrane K02457,K02458,K08084 - - 0.00001281 53.0
MMD2_k127_3449020_18 Prokaryotic N-terminal methylation motif K12285 - - 0.0001227 51.0
MMD2_k127_3449020_19 Phosphotransferase enzyme family - - - 0.0002166 52.0
MMD2_k127_3449020_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 340.0
MMD2_k127_3449020_20 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0005679 45.0
MMD2_k127_3449020_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003637 283.0
MMD2_k127_3449020_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 277.0
MMD2_k127_3449020_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005413 262.0
MMD2_k127_3449020_6 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003504 247.0
MMD2_k127_3449020_7 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000001142 226.0
MMD2_k127_3449020_8 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000009711 214.0
MMD2_k127_3449020_9 glycogen (starch) synthase activity - - - 0.0000000000000000000000000000000000000002364 158.0
MMD2_k127_3451817_0 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002258 279.0
MMD2_k127_3451817_1 Transposase and inactivated derivatives - - - 0.000000000000000002332 87.0
MMD2_k127_3451817_2 DegV family - - - 0.00000000000000003633 92.0
MMD2_k127_3501330_0 Uncharacterised protein conserved in bacteria (DUF2326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 441.0
MMD2_k127_3501330_1 - - - - 0.000000000002345 70.0
MMD2_k127_3662513_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 349.0
MMD2_k127_3662513_1 domain protein K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000001478 214.0
MMD2_k127_3662905_0 macromolecule localization K01421,K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000002654 211.0
MMD2_k127_3662905_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000001808 169.0
MMD2_k127_3662905_2 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000001859 169.0
MMD2_k127_3662905_3 ABC transporter K01990 - - 0.000000000000000001305 90.0
MMD2_k127_3748655_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 531.0
MMD2_k127_3748655_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000002788 196.0
MMD2_k127_3748655_2 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000002987 178.0
MMD2_k127_3748655_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000005813 140.0
MMD2_k127_3748655_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003521 77.0
MMD2_k127_3750577_0 PAS domain K07652 - 2.7.13.3 0.0000000000000000000000000000000000000000002837 176.0
MMD2_k127_3750577_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000001641 83.0
MMD2_k127_3786245_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000002008 76.0
MMD2_k127_3786245_1 Type IV pilus assembly protein PilM; K02662 - - 0.0003 49.0
MMD2_k127_3813506_0 NUDIX domain K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000121 205.0
MMD2_k127_3813506_1 UbiA prenyltransferase family K20616 - - 0.000000000000000000000000004071 120.0
MMD2_k127_3813506_2 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000005608 110.0
MMD2_k127_3813506_3 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.000000000000000000022 94.0
MMD2_k127_3813506_4 NUDIX domain - - - 0.000000000000008907 80.0
MMD2_k127_3916044_0 DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 350.0
MMD2_k127_3916044_1 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 301.0
MMD2_k127_3916044_3 - - - - 0.00000000008856 70.0
MMD2_k127_3916044_4 HNH nucleases - - - 0.0000003208 58.0
MMD2_k127_3916044_5 - - - - 0.00001897 49.0
MMD2_k127_3927385_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000009235 135.0
MMD2_k127_3927385_1 hydrolase, TatD K03424 - - 0.000000000000000000000000007205 116.0
MMD2_k127_3927385_2 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000001625 94.0
MMD2_k127_3961026_0 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001801 282.0
MMD2_k127_3977197_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001288 289.0
MMD2_k127_3977197_1 AI-2E family transporter - - - 0.0000000000000000000000000000000002358 145.0
MMD2_k127_3977197_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000002128 131.0
MMD2_k127_4018514_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 397.0
MMD2_k127_4025158_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.301e-218 699.0
MMD2_k127_4025158_1 NYN domain - - - 0.000000000000000000000000000000000000000000000000002057 187.0
MMD2_k127_4025158_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000006792 97.0
MMD2_k127_4099516_0 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000002996 94.0
MMD2_k127_4100096_0 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 347.0
MMD2_k127_4100096_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 336.0
MMD2_k127_4100096_2 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
MMD2_k127_4100096_3 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000006685 119.0
MMD2_k127_4131076_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 541.0
MMD2_k127_4131076_1 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 451.0
MMD2_k127_4131076_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000753 143.0
MMD2_k127_4131076_11 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000001702 111.0
MMD2_k127_4131076_12 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000007885 66.0
MMD2_k127_4131076_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000004397 59.0
MMD2_k127_4131076_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000002273 59.0
MMD2_k127_4131076_15 Probable zinc-ribbon domain - - - 0.0002202 54.0
MMD2_k127_4131076_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 386.0
MMD2_k127_4131076_3 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 379.0
MMD2_k127_4131076_4 Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 325.0
MMD2_k127_4131076_5 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
MMD2_k127_4131076_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
MMD2_k127_4131076_7 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000007102 228.0
MMD2_k127_4131076_8 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.0000000000000000000000000000000000000000000003169 181.0
MMD2_k127_4131076_9 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000000000000000002604 153.0
MMD2_k127_4135298_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.184e-227 720.0
MMD2_k127_4135298_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 452.0
MMD2_k127_4135298_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 332.0
MMD2_k127_4135298_3 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000003976 242.0
MMD2_k127_4135298_4 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000001586 231.0
MMD2_k127_4135298_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001083 188.0
MMD2_k127_4135298_6 dUTP biosynthetic process K01494 - 3.5.4.13 0.0000000000000000000000001559 113.0
MMD2_k127_4135298_7 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.00000001854 57.0
MMD2_k127_4135298_8 dephospho-CoA kinase activity - - - 0.0000002914 59.0
MMD2_k127_4135901_0 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000002475 138.0
MMD2_k127_4135901_1 Trp repressor protein - - - 0.00000000000001318 77.0
MMD2_k127_4203041_0 PFAM UDP-glucose GDP-mannose dehydrogenase K00066,K02472,K02474,K13015 - 1.1.1.132,1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 460.0
MMD2_k127_4203041_1 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 292.0
MMD2_k127_4203041_2 O-antigen - - - 0.000004393 57.0
MMD2_k127_4234901_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 316.0
MMD2_k127_423904_0 Belongs to the glutamate synthase family - - - 1.287e-194 615.0
MMD2_k127_423904_1 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000006589 58.0
MMD2_k127_423904_2 PFAM Peptidase C60, sortase A B K07284 - 3.4.22.70 0.000004602 56.0
MMD2_k127_423904_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0006305 51.0
MMD2_k127_4270391_0 PDZ domain (Also known as DHR or GLGF) - - - 0.000000000000000000000000000000000000000000000000000003301 204.0
MMD2_k127_4270391_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000653 184.0
MMD2_k127_4270391_2 beta-galactosidase activity K01219,K21000 - 3.2.1.81 0.00000000000000000000000000000000005735 146.0
MMD2_k127_4270391_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.000000000000000000000000000001235 123.0
MMD2_k127_4273680_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 451.0
MMD2_k127_4273680_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000001815 173.0
MMD2_k127_4273680_2 COG0451 Nucleoside-diphosphate-sugar epimerases K19068 - 1.1.1.367 0.0000000000000000000005025 99.0
MMD2_k127_4273680_3 Glycosyl transferases group 1 - - - 0.000000000000000000004107 94.0
MMD2_k127_4337689_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000107 169.0
MMD2_k127_4337689_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000007406 101.0
MMD2_k127_4337689_2 Psort location CytoplasmicMembrane, score 9.99 K07301 - - 0.00000000491 64.0
MMD2_k127_4433992_0 SWI complex, BAF60b domains - - - 0.0000000000000000000000000002086 115.0
MMD2_k127_4433992_1 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000004216 122.0
MMD2_k127_4433992_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000005278 100.0
MMD2_k127_4433992_3 Aminoacyl-tRNA editing domain - - - 0.00000000001763 71.0
MMD2_k127_4466438_0 COGs COG5421 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 376.0
MMD2_k127_4466438_1 PFAM Queuosine biosynthesis protein K07568 - 2.4.99.17 0.0000000000000000000000000004044 115.0
MMD2_k127_4577798_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003344 263.0
MMD2_k127_4577798_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000004888 253.0
MMD2_k127_4577798_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000765 236.0
MMD2_k127_4577798_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000006302 188.0
MMD2_k127_4577798_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000005047 145.0
MMD2_k127_4577798_5 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000001478 99.0
MMD2_k127_4577798_6 Leucine rich repeats (6 copies) - - - 0.000009275 52.0
MMD2_k127_4693628_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000001752 186.0
MMD2_k127_4701217_0 CDP-glucose 4,6-dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 268.0
MMD2_k127_4701217_1 TIGRFAM Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000004247 134.0
MMD2_k127_4701217_2 Methyltransferase domain - - - 0.0000000000000000000001316 104.0
MMD2_k127_4701286_0 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 415.0
MMD2_k127_4701286_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 400.0
MMD2_k127_4701286_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000001092 58.0
MMD2_k127_4701286_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000001733 60.0
MMD2_k127_4701286_12 TIGRFAM sporulation protein, yteA family - - - 0.0000001603 58.0
MMD2_k127_4701286_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 370.0
MMD2_k127_4701286_3 Type IV secretory pathway, VirB4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001831 273.0
MMD2_k127_4701286_4 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003566 227.0
MMD2_k127_4701286_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001139 220.0
MMD2_k127_4701286_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000001434 161.0
MMD2_k127_4701286_7 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.0000000000000000000000000000003094 132.0
MMD2_k127_4701286_8 Type IV secretory pathway, VirB4 - - - 0.0000000000000000000003135 103.0
MMD2_k127_4701286_9 Jag N-terminus K06346 - - 0.000000000000000006154 89.0
MMD2_k127_4733913_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 340.0
MMD2_k127_4733913_1 Evidence 5 No homology to any previously reported sequences K09005 - - 0.000000000000000000000000001763 115.0
MMD2_k127_4733913_2 Endonuclease containing a URI domain K07461 - - 0.0000000000002048 71.0
MMD2_k127_4733913_3 GtrA-like protein - - - 0.00000007623 61.0
MMD2_k127_4733913_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000001295 61.0
MMD2_k127_4765749_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 325.0
MMD2_k127_4765749_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000004134 196.0
MMD2_k127_4767066_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000003917 185.0
MMD2_k127_4767066_1 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000137 127.0
MMD2_k127_4767066_2 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000001072 94.0
MMD2_k127_4767066_3 - K00960 - 2.7.7.6 0.00000000003495 65.0
MMD2_k127_4767066_4 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000008934 60.0
MMD2_k127_4825130_0 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 527.0
MMD2_k127_4825130_1 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 350.0
MMD2_k127_4825130_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 299.0
MMD2_k127_4825130_3 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003891 262.0
MMD2_k127_4825130_4 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000004594 184.0
MMD2_k127_4861410_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.599e-200 637.0
MMD2_k127_4861410_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 342.0
MMD2_k127_4911545_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.141e-282 889.0
MMD2_k127_4911545_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.827e-202 646.0
MMD2_k127_4911545_2 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 353.0
MMD2_k127_4911545_3 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 327.0
MMD2_k127_4911545_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001443 270.0
MMD2_k127_5018509_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 366.0
MMD2_k127_5018673_0 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000048 227.0
MMD2_k127_5018673_2 - - - - 0.00000126 54.0
MMD2_k127_5018673_3 Terminase small subunit - - - 0.0008371 48.0
MMD2_k127_504229_0 - - - - 0.0001017 52.0
MMD2_k127_5064460_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000004303 240.0
MMD2_k127_5064460_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000007041 98.0
MMD2_k127_5064460_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000004826 59.0
MMD2_k127_5091667_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.719e-241 763.0
MMD2_k127_5091667_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 524.0
MMD2_k127_5091667_10 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000004566 106.0
MMD2_k127_5091667_11 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000001197 102.0
MMD2_k127_5091667_12 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000001586 108.0
MMD2_k127_5091667_13 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000002733 94.0
MMD2_k127_5091667_14 Protein of unknown function (DUF763) K09003 - - 0.000000000000000006168 83.0
MMD2_k127_5091667_15 Binds directly to 16S ribosomal RNA K02968 - - 0.000000002413 61.0
MMD2_k127_5091667_16 Ammonium Transporter Family K03320 - - 0.00008826 53.0
MMD2_k127_5091667_2 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 341.0
MMD2_k127_5091667_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002732 271.0
MMD2_k127_5091667_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000006297 244.0
MMD2_k127_5091667_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001961 237.0
MMD2_k127_5091667_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000004076 215.0
MMD2_k127_5091667_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000005975 117.0
MMD2_k127_5091667_8 PFAM response regulator receiver K07657 - - 0.0000000000000000000000002679 109.0
MMD2_k127_5091667_9 PFAM response regulator receiver K07657 - - 0.0000000000000000000000009893 107.0
MMD2_k127_512489_0 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000007433 81.0
MMD2_k127_5143404_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 315.0
MMD2_k127_5143404_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001543 217.0
MMD2_k127_5143404_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000004027 202.0
MMD2_k127_5143404_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000005179 117.0
MMD2_k127_5143404_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000002654 100.0
MMD2_k127_5143404_5 electron transfer activity K03439,K05337 - 2.1.1.33 0.00000000000234 69.0
MMD2_k127_5143404_6 Membrane-bound lytic murein transglycosylase B K08305 - - 0.00004049 56.0
MMD2_k127_5144400_0 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000002415 244.0
MMD2_k127_5144400_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K07025 - - 0.000000000000000000000000000000000000001345 153.0
MMD2_k127_5144400_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000009375 136.0
MMD2_k127_5144400_3 Protein of unknown function (DUF4446) - - - 0.000000000000009981 78.0
MMD2_k127_5145358_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 468.0
MMD2_k127_5145358_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 356.0
MMD2_k127_5145358_2 SMART Peptidase A22, presenilin signal peptide - - - 0.00000001225 65.0
MMD2_k127_5150637_0 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000215 203.0
MMD2_k127_5150637_1 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000008084 128.0
MMD2_k127_5150637_2 - - - - 0.000000000000000000000006605 106.0
MMD2_k127_5150637_3 Essential cell division protein K03589 - - 0.00000001357 65.0
MMD2_k127_5150637_4 EamA-like transporter family K08978 - - 0.0000002875 54.0
MMD2_k127_5193612_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 614.0
MMD2_k127_5193612_1 Type IV Pilus-assembly protein W K02672 - - 0.0006514 49.0
MMD2_k127_5202799_0 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000001432 176.0
MMD2_k127_5205009_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009798 282.0
MMD2_k127_5205009_1 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000001022 215.0
MMD2_k127_5205009_2 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000004887 113.0
MMD2_k127_5205009_3 phosphoglycerate mutase K22305 - 3.1.3.3 0.000002886 57.0
MMD2_k127_5205009_4 PFAM nuclease (SNase K01174 - 3.1.31.1 0.000447 42.0
MMD2_k127_5215711_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 415.0
MMD2_k127_5288696_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 299.0
MMD2_k127_5288696_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000003282 211.0
MMD2_k127_5288696_10 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000004457 93.0
MMD2_k127_5288696_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000002336 74.0
MMD2_k127_5288696_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000003356 51.0
MMD2_k127_5288696_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000001273 205.0
MMD2_k127_5288696_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000811 166.0
MMD2_k127_5288696_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000005205 153.0
MMD2_k127_5288696_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000008395 151.0
MMD2_k127_5288696_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000007929 131.0
MMD2_k127_5288696_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000005717 119.0
MMD2_k127_5288696_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000001052 115.0
MMD2_k127_5288696_9 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005058 102.0
MMD2_k127_532327_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 515.0
MMD2_k127_532327_1 protein transport K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 351.0
MMD2_k127_532327_10 Cell division protein FtsA - - - 0.000000000000000000000006895 115.0
MMD2_k127_532327_11 Binds to the 23S rRNA K02876 - - 0.00000000000000005332 86.0
MMD2_k127_532327_12 TM2 domain - - - 0.000000001473 61.0
MMD2_k127_532327_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000008929 53.0
MMD2_k127_532327_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
MMD2_k127_532327_3 triose-phosphate isomerase activity K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001891 238.0
MMD2_k127_532327_4 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000003353 227.0
MMD2_k127_532327_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000002254 211.0
MMD2_k127_532327_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000381 146.0
MMD2_k127_532327_7 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006184 143.0
MMD2_k127_532327_8 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K09776 - - 0.000000000000000000000000000000003712 134.0
MMD2_k127_532327_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000001046 130.0
MMD2_k127_5396283_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 509.0
MMD2_k127_5396283_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000002994 195.0
MMD2_k127_5412974_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000003955 209.0
MMD2_k127_5413682_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 3.317e-282 904.0
MMD2_k127_5413682_1 Arginyl tRNA synthetase N terminal domain K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 316.0
MMD2_k127_5413682_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0002127 46.0
MMD2_k127_5468278_0 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 344.0
MMD2_k127_5479306_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1122.0
MMD2_k127_5479306_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.081e-195 623.0
MMD2_k127_5479306_2 Subtilase family K13274,K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001746 287.0
MMD2_k127_5479306_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000021 231.0
MMD2_k127_5479306_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000001102 212.0
MMD2_k127_5479306_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000006053 118.0
MMD2_k127_5479306_6 histidine kinase A domain protein - - - 0.000000000009747 68.0
MMD2_k127_5479306_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000001425 63.0
MMD2_k127_5479306_8 Fn3 associated - - - 0.0005151 52.0
MMD2_k127_5516635_0 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000004799 183.0
MMD2_k127_5516635_1 Cysteine-rich secretory protein family - - - 0.00000000000000000000002572 111.0
MMD2_k127_5516635_2 Domain of unknown function (DUF4342) - - - 0.00000000000000005929 81.0
MMD2_k127_5516635_3 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000005932 85.0
MMD2_k127_5516635_4 Belongs to the glutamate synthase family - - - 0.00000000000002166 73.0
MMD2_k127_5523955_0 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002023 231.0
MMD2_k127_5523955_1 NUDIX domain - - - 0.00000000002905 70.0
MMD2_k127_5639888_0 MgtC family K07507 - - 0.0000000000000000000000000000000001305 138.0
MMD2_k127_5639888_1 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000001497 127.0
MMD2_k127_5639888_2 peptidase U32 - - - 0.0000000000000000001408 90.0
MMD2_k127_5639888_3 Transmembrane amino acid transporter protein - - - 0.0000000000000001949 90.0
MMD2_k127_5639888_4 methyltransferase activity K02169 - 2.1.1.197 0.000000000007092 71.0
MMD2_k127_5640220_0 valine-tRNA ligase activity K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.591e-258 813.0
MMD2_k127_5640220_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 397.0
MMD2_k127_5640220_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000004094 57.0
MMD2_k127_5640220_11 Protein of unknown function (DUF4446) - - - 0.00005127 46.0
MMD2_k127_5640220_12 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0006524 42.0
MMD2_k127_5640220_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000008856 265.0
MMD2_k127_5640220_3 dihydroorotate dehydrogenase activity K00226,K02823,K17828 - 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000003212 216.0
MMD2_k127_5640220_4 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000231 184.0
MMD2_k127_5640220_5 large ribosomal subunit rRNA binding K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005837 135.0
MMD2_k127_5640220_6 Protease prsW family - - - 0.000000000000000001426 95.0
MMD2_k127_5640220_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000006125 83.0
MMD2_k127_5640220_8 3D domain protein - - - 0.000000000008141 72.0
MMD2_k127_5640220_9 - - - - 0.00000002676 57.0
MMD2_k127_5664417_0 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 329.0
MMD2_k127_5689446_0 methyltransferase K16648 - - 0.000000000000000000000000000000000000000000000000109 184.0
MMD2_k127_5709105_0 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 359.0
MMD2_k127_5709105_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000004672 113.0
MMD2_k127_5709105_2 - - - - 0.000000000000000005134 92.0
MMD2_k127_5709105_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000001436 56.0
MMD2_k127_5724495_0 Biogenesis protein K02275,K09792,K17686 - 1.9.3.1,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 316.0
MMD2_k127_5724495_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000006213 141.0
MMD2_k127_5724495_2 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000002116 93.0
MMD2_k127_5724495_3 Belongs to the UPF0235 family K09131 - - 0.0000008214 53.0
MMD2_k127_5729239_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 372.0
MMD2_k127_5729239_1 domain HDIG-containing protein K06951 - - 0.000000000000000000000000000000000000000000000000000000000006613 213.0
MMD2_k127_5729239_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000007241 161.0
MMD2_k127_5729239_3 Alpha/beta hydrolase family K00433 - 1.11.1.10 0.00000000000000000000000000000000007442 141.0
MMD2_k127_5741401_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 308.0
MMD2_k127_5741401_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 302.0
MMD2_k127_5741401_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
MMD2_k127_5741401_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000001407 257.0
MMD2_k127_5741401_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000001042 246.0
MMD2_k127_5797746_0 membrane protein involved in D-alanine export K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 387.0
MMD2_k127_5797746_1 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.0000000000000000000000000000000000000000008015 169.0
MMD2_k127_5797746_2 Bacterial membrane protein, YfhO - - - 0.00001929 51.0
MMD2_k127_5842393_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000005778 248.0
MMD2_k127_5842393_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000007354 190.0
MMD2_k127_5842393_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000003653 150.0
MMD2_k127_5842393_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000878 148.0
MMD2_k127_5842393_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000001971 129.0
MMD2_k127_5842393_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000002341 116.0
MMD2_k127_5842393_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000002925 91.0
MMD2_k127_5842393_7 Ribosomal protein L17 K02879 - - 0.0000000000000000003652 91.0
MMD2_k127_5842393_8 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001025 65.0
MMD2_k127_5875192_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000003863 143.0
MMD2_k127_5875192_1 CRISPR-associated protein Cas4 K07464 GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0032392,GO:0032508,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0048037,GO:0051276,GO:0051536,GO:0051537,GO:0051540,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.12.1 0.000000000001301 76.0
MMD2_k127_5894455_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000001531 206.0
MMD2_k127_5894455_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000007131 166.0
MMD2_k127_5943487_0 Type IV secretory pathway, VirB4 - - - 0.000000000000000000001891 99.0
MMD2_k127_5943487_1 - - - - 0.000000002381 66.0
MMD2_k127_5943487_2 SMART band 7 protein - - - 0.00000002865 66.0
MMD2_k127_5943487_3 Outer membrane lipoprotein - - - 0.0000009501 61.0
MMD2_k127_5943487_4 Psort location Cytoplasmic, score 7.50 - - - 0.0003371 47.0
MMD2_k127_596721_0 myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 516.0
MMD2_k127_596721_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000001281 121.0
MMD2_k127_596721_2 DNA polymerase X family K02347 - - 0.000000000000000001043 94.0
MMD2_k127_596721_3 Transcriptional regulator PadR-like family - - - 0.000000000000006999 78.0
MMD2_k127_596721_4 Transcriptional regulator PadR-like family - - - 0.0000009696 54.0
MMD2_k127_6041582_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000001083 196.0
MMD2_k127_6041582_1 ferredoxin-thioredoxin reductase activity - - - 0.000000000000003879 78.0
MMD2_k127_6041582_2 cell redox homeostasis - - - 0.000000000001762 70.0
MMD2_k127_6041582_3 Domain of unknown function (DUF4163) K22278 - 3.5.1.104 0.00000000000881 75.0
MMD2_k127_6041582_4 self proteolysis K09800,K11021,K13735 - - 0.0000000000183 76.0
MMD2_k127_6041582_5 Rubrerythrin - - - 0.0002039 47.0
MMD2_k127_6041582_6 Papain family cysteine protease - - - 0.0002592 49.0
MMD2_k127_6147988_0 Domain of unknown function (DUF4372) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 420.0
MMD2_k127_6158042_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 592.0
MMD2_k127_6158042_1 PFAM Carbamoyl-phosphate synthase L chain K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 421.0
MMD2_k127_6158042_2 enoyl-(acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 277.0
MMD2_k127_6158042_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.000000000000000000000000000000000000000000000000000000005216 204.0
MMD2_k127_6158042_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000007573 130.0
MMD2_k127_6158042_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000001287 127.0
MMD2_k127_6158042_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000001742 115.0
MMD2_k127_6158042_7 Biotin carboxyl carrier protein - - - 0.000000008018 62.0
MMD2_k127_6158042_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00001458 51.0
MMD2_k127_6198577_0 Heat shock 70 kDa protein K04043 - - 5.334e-213 677.0
MMD2_k127_6212307_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876,K09759 - 6.1.1.12,6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 381.0
MMD2_k127_6212307_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000008275 173.0
MMD2_k127_6212307_2 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000003312 111.0
MMD2_k127_6212307_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000002044 98.0
MMD2_k127_6259799_0 dGTPase activity K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000002951 239.0
MMD2_k127_6259799_1 - - - - 0.000000000000000001933 87.0
MMD2_k127_6259892_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 321.0
MMD2_k127_6259892_1 Dak2 K07030 - - 0.000000000000000000000000000000000000000008752 177.0
MMD2_k127_6259892_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000001375 98.0
MMD2_k127_6259892_3 Belongs to the UPF0102 family K07460 - - 0.000000000000008867 78.0
MMD2_k127_6259892_4 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000001631 65.0
MMD2_k127_63850_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.105e-197 630.0
MMD2_k127_63850_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 481.0
MMD2_k127_63850_2 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 451.0
MMD2_k127_63850_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007045 279.0
MMD2_k127_63850_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000442 246.0
MMD2_k127_63850_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000003215 209.0
MMD2_k127_63850_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000001668 165.0
MMD2_k127_63850_7 phosphorelay signal transduction system - - - 0.0000000000000000000009623 99.0
MMD2_k127_676204_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 384.0
MMD2_k127_676204_1 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
MMD2_k127_676204_2 - - - - 0.00000000000000000000000000000000000000000000000000000006073 200.0
MMD2_k127_676204_3 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000008457 203.0
MMD2_k127_702644_0 PFAM aspartate glutamate uridylate kinase K00931,K03430,K06981 - 2.6.1.37,2.7.2.11,2.7.4.26 0.000000000000000000000000000000000000000000000000006843 190.0
MMD2_k127_702644_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000308 53.0
MMD2_k127_7412_0 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000001107 104.0
MMD2_k127_7412_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000003336 70.0
MMD2_k127_777464_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000007568 225.0
MMD2_k127_777464_1 Capsule biosynthesis protein K07282 - - 0.00000000000000000000006374 104.0
MMD2_k127_777464_2 Probable zinc-ribbon domain - - - 0.000000001123 61.0
MMD2_k127_796688_0 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000008361 142.0
MMD2_k127_796688_1 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000005028 126.0
MMD2_k127_98524_0 DNA polymerase - - - 0.0000000000000000384 93.0