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Overview

ID MAG02745
Name MMS2_bin.54
Sample SMP0065
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus RI-121
Species
Assembly information
Completeness (%) 77.74
Contamination (%) 0.07
GC content (%) 58.0
N50 (bp) 33,086
Genome size (bp) 1,795,382

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1807

Gene name Description KEGG GOs EC E-value Score Sequence
MMS2_k127_1019525_0 von Willebrand factor (vWF) type A domain - - - 0.0 1433.0
MMS2_k127_1019525_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1328.0
MMS2_k127_1019525_10 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.795e-256 797.0
MMS2_k127_1019525_11 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.734e-249 775.0
MMS2_k127_1019525_12 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 2.291e-223 695.0
MMS2_k127_1019525_13 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.282e-219 693.0
MMS2_k127_1019525_14 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.351e-207 653.0
MMS2_k127_1019525_15 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 1.769e-206 644.0
MMS2_k127_1019525_16 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 8.94e-197 615.0
MMS2_k127_1019525_17 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 610.0
MMS2_k127_1019525_18 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 541.0
MMS2_k127_1019525_19 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 533.0
MMS2_k127_1019525_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1270.0
MMS2_k127_1019525_20 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 502.0
MMS2_k127_1019525_21 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 483.0
MMS2_k127_1019525_22 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 481.0
MMS2_k127_1019525_23 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 464.0
MMS2_k127_1019525_24 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 449.0
MMS2_k127_1019525_25 LysR substrate binding domain K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 431.0
MMS2_k127_1019525_26 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 424.0
MMS2_k127_1019525_27 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 402.0
MMS2_k127_1019525_28 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 400.0
MMS2_k127_1019525_29 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 387.0
MMS2_k127_1019525_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1268.0
MMS2_k127_1019525_30 oxidoreductase FAD NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 370.0
MMS2_k127_1019525_31 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 358.0
MMS2_k127_1019525_32 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 299.0
MMS2_k127_1019525_33 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 291.0
MMS2_k127_1019525_34 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007037 280.0
MMS2_k127_1019525_35 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005611 273.0
MMS2_k127_1019525_36 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005428 262.0
MMS2_k127_1019525_37 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000008774 259.0
MMS2_k127_1019525_38 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000001845 239.0
MMS2_k127_1019525_39 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000000006 217.0
MMS2_k127_1019525_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1024.0
MMS2_k127_1019525_40 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000009737 218.0
MMS2_k127_1019525_41 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000001186 219.0
MMS2_k127_1019525_42 Protein of unknown function (DUF494) K03747 - - 0.000000000000000000000000000000000000000000000000000000000002642 211.0
MMS2_k127_1019525_43 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000003169 211.0
MMS2_k127_1019525_44 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000000000001183 210.0
MMS2_k127_1019525_45 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.0000000000000000000000000000000000000000000000000000000002556 204.0
MMS2_k127_1019525_46 TIGRFAM transcriptional regulator, Rrf2 family K13771 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
MMS2_k127_1019525_47 - - - - 0.0000000000000000000000000000000000000000000000004106 180.0
MMS2_k127_1019525_48 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000000001384 169.0
MMS2_k127_1019525_49 - - - - 0.000000000000000000000000000000000000000003329 156.0
MMS2_k127_1019525_5 Ribulose bisphosphate carboxylase large chain, catalytic domain - - - 5.125e-319 976.0
MMS2_k127_1019525_50 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000001263 118.0
MMS2_k127_1019525_51 - - - - 0.00000000000000000000000006071 107.0
MMS2_k127_1019525_52 - - - - 0.0000000000000000000003834 103.0
MMS2_k127_1019525_53 Ribonuclease P K03536 - 3.1.26.5 0.00000000000000000002348 95.0
MMS2_k127_1019525_54 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000305 76.0
MMS2_k127_1019525_56 ATP synthase I chain K02116 - - 0.00000008574 59.0
MMS2_k127_1019525_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.52e-300 923.0
MMS2_k127_1019525_7 histidine kinase HAMP region domain protein - - - 9.169e-299 931.0
MMS2_k127_1019525_8 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.67e-292 906.0
MMS2_k127_1019525_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.054e-279 863.0
MMS2_k127_1020014_0 DinB superfamily - - - 0.0 1113.0
MMS2_k127_1020014_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 5.809e-279 878.0
MMS2_k127_1020014_10 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 324.0
MMS2_k127_1020014_11 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
MMS2_k127_1020014_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000001977 207.0
MMS2_k127_1020014_13 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000004725 222.0
MMS2_k127_1020014_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000001371 187.0
MMS2_k127_1020014_15 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000000000000000000000000333 190.0
MMS2_k127_1020014_16 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000002617 172.0
MMS2_k127_1020014_17 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000001834 163.0
MMS2_k127_1020014_18 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000001687 157.0
MMS2_k127_1020014_19 Protein of unknown function (DUF3293) - - - 0.00000000000000000000000000000000000000005728 156.0
MMS2_k127_1020014_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.068e-234 736.0
MMS2_k127_1020014_20 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000007645 129.0
MMS2_k127_1020014_21 Phosphoglycerate mutase family - - - 0.000000000000273 77.0
MMS2_k127_1020014_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 588.0
MMS2_k127_1020014_4 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 514.0
MMS2_k127_1020014_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 470.0
MMS2_k127_1020014_6 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 430.0
MMS2_k127_1020014_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 415.0
MMS2_k127_1020014_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 344.0
MMS2_k127_1020014_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 326.0
MMS2_k127_1042593_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 1.143e-199 628.0
MMS2_k127_1042593_1 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 571.0
MMS2_k127_1042593_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 533.0
MMS2_k127_1042593_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 501.0
MMS2_k127_1042593_4 heptosyltransferase K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 409.0
MMS2_k127_1042593_5 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
MMS2_k127_1042593_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000001726 197.0
MMS2_k127_1042593_7 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000004873 57.0
MMS2_k127_1146415_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1568.0
MMS2_k127_1146415_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1496.0
MMS2_k127_1146415_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.146e-229 715.0
MMS2_k127_1146415_11 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 2.272e-220 693.0
MMS2_k127_1146415_12 PFAM Type II secretion system F domain K02653 - - 7.902e-214 668.0
MMS2_k127_1146415_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 6.501e-207 649.0
MMS2_k127_1146415_14 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 1.812e-201 627.0
MMS2_k127_1146415_15 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 6.305e-199 624.0
MMS2_k127_1146415_16 Domain of unknown function DUF21 - - - 5.034e-195 616.0
MMS2_k127_1146415_17 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 601.0
MMS2_k127_1146415_18 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 582.0
MMS2_k127_1146415_19 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 598.0
MMS2_k127_1146415_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1091.0
MMS2_k127_1146415_20 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 561.0
MMS2_k127_1146415_21 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 561.0
MMS2_k127_1146415_22 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 535.0
MMS2_k127_1146415_23 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 515.0
MMS2_k127_1146415_24 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 523.0
MMS2_k127_1146415_25 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 483.0
MMS2_k127_1146415_26 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 471.0
MMS2_k127_1146415_27 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 476.0
MMS2_k127_1146415_28 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 462.0
MMS2_k127_1146415_29 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 454.0
MMS2_k127_1146415_3 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 6.353e-300 924.0
MMS2_k127_1146415_30 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 447.0
MMS2_k127_1146415_31 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 409.0
MMS2_k127_1146415_32 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 412.0
MMS2_k127_1146415_33 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 387.0
MMS2_k127_1146415_34 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 382.0
MMS2_k127_1146415_35 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 384.0
MMS2_k127_1146415_36 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 368.0
MMS2_k127_1146415_37 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 349.0
MMS2_k127_1146415_38 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 308.0
MMS2_k127_1146415_39 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 322.0
MMS2_k127_1146415_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 2.246e-266 826.0
MMS2_k127_1146415_40 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 292.0
MMS2_k127_1146415_41 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 282.0
MMS2_k127_1146415_42 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 289.0
MMS2_k127_1146415_43 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 279.0
MMS2_k127_1146415_44 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421 270.0
MMS2_k127_1146415_45 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002468 253.0
MMS2_k127_1146415_46 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 252.0
MMS2_k127_1146415_47 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000005731 248.0
MMS2_k127_1146415_48 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000001066 230.0
MMS2_k127_1146415_49 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000002607 208.0
MMS2_k127_1146415_5 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.18e-262 820.0
MMS2_k127_1146415_50 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000001952 217.0
MMS2_k127_1146415_51 POTRA domain, FtsQ-type - - - 0.00000000000000000000000000000000000000001173 162.0
MMS2_k127_1146415_52 - - - - 0.000000000000000000000000000000000000001626 154.0
MMS2_k127_1146415_53 Chorismate lyase K03181 - 4.1.3.40 0.00000000000000000000000000000000000001298 154.0
MMS2_k127_1146415_54 Bacterial regulatory protein, Fis family K03557 - - 0.00000000000000000000000000000000001967 136.0
MMS2_k127_1146415_55 Ribosomal silencing factor during starvation K09710 - - 0.00000000000000000000000000000000003316 140.0
MMS2_k127_1146415_56 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000000002688 125.0
MMS2_k127_1146415_57 Protein of unknown function (DUF721) - - - 0.000000000000000000000008043 106.0
MMS2_k127_1146415_58 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000007727 91.0
MMS2_k127_1146415_59 - - - - 0.000000000000006383 79.0
MMS2_k127_1146415_6 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 4.996e-247 776.0
MMS2_k127_1146415_60 - - - - 0.0000000000004346 71.0
MMS2_k127_1146415_61 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000001534 67.0
MMS2_k127_1146415_7 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 1.687e-237 742.0
MMS2_k127_1146415_8 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 3.126e-235 732.0
MMS2_k127_1146415_9 Mur ligase family, catalytic domain K01924 - 6.3.2.8 6.436e-235 733.0
MMS2_k127_1165103_0 HELICc2 K03722 - 3.6.4.12 0.0 1020.0
MMS2_k127_1165103_1 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001306 270.0
MMS2_k127_1165103_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000004829 69.0
MMS2_k127_128543_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1560.0
MMS2_k127_128543_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1452.0
MMS2_k127_128543_10 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 1.023e-220 706.0
MMS2_k127_128543_11 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 582.0
MMS2_k127_128543_12 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 576.0
MMS2_k127_128543_13 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 552.0
MMS2_k127_128543_14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 544.0
MMS2_k127_128543_15 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 542.0
MMS2_k127_128543_16 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 543.0
MMS2_k127_128543_17 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 492.0
MMS2_k127_128543_18 Bacteriophage replication gene A protein (GPA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 496.0
MMS2_k127_128543_19 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 463.0
MMS2_k127_128543_2 Neisseria PilC beta-propeller domain K02674 - - 0.0 1370.0
MMS2_k127_128543_20 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 454.0
MMS2_k127_128543_21 HD domain K07814,K13815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 453.0
MMS2_k127_128543_22 LysR substrate binding domain K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 445.0
MMS2_k127_128543_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
MMS2_k127_128543_24 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 430.0
MMS2_k127_128543_25 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 417.0
MMS2_k127_128543_26 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 421.0
MMS2_k127_128543_27 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 394.0
MMS2_k127_128543_28 hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 392.0
MMS2_k127_128543_29 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 392.0
MMS2_k127_128543_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1112.0
MMS2_k127_128543_30 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 389.0
MMS2_k127_128543_31 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 385.0
MMS2_k127_128543_32 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 393.0
MMS2_k127_128543_33 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 370.0
MMS2_k127_128543_34 Enoyl-CoA hydratase/isomerase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 370.0
MMS2_k127_128543_35 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 368.0
MMS2_k127_128543_36 diguanylate cyclase K07216 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 376.0
MMS2_k127_128543_37 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 360.0
MMS2_k127_128543_38 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 346.0
MMS2_k127_128543_39 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 323.0
MMS2_k127_128543_4 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 3.138e-318 986.0
MMS2_k127_128543_40 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 302.0
MMS2_k127_128543_41 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 291.0
MMS2_k127_128543_42 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000004767 240.0
MMS2_k127_128543_43 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000008372 232.0
MMS2_k127_128543_44 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000006093 202.0
MMS2_k127_128543_45 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000007345 202.0
MMS2_k127_128543_46 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000002531 181.0
MMS2_k127_128543_47 COG0314 Molybdopterin converting factor, large subunit K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.00000000000000000000000000000000000000000000000004815 186.0
MMS2_k127_128543_48 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000008184 168.0
MMS2_k127_128543_49 response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000005886 156.0
MMS2_k127_128543_5 Cysteine-rich domain - - - 7.406e-287 887.0
MMS2_k127_128543_50 Prokaryotic N-terminal methylation motif K08084 - - 0.0000000000000000000000000000000000000004439 156.0
MMS2_k127_128543_51 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000006566 157.0
MMS2_k127_128543_52 Protein of unknown function (DUF2971) - - - 0.000000000000000000000000000000000000006958 154.0
MMS2_k127_128543_53 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000000000003322 147.0
MMS2_k127_128543_54 - - - - 0.00000000000000000000000000000000000005784 149.0
MMS2_k127_128543_55 Glyoxalase-like domain - - - 0.0000000000000000000000000000001082 128.0
MMS2_k127_128543_56 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000001562 126.0
MMS2_k127_128543_57 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000004955 115.0
MMS2_k127_128543_58 cytochrome - - - 0.00000000000000000000000001171 113.0
MMS2_k127_128543_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 5.087e-253 786.0
MMS2_k127_128543_60 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000002983 102.0
MMS2_k127_128543_61 Helix-turn-helix domain - - - 0.00000000000000000001709 92.0
MMS2_k127_128543_62 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000008809 74.0
MMS2_k127_128543_63 - - - - 0.0001754 45.0
MMS2_k127_128543_7 May be involved in recombinational repair of damaged DNA K03631 - - 2.733e-250 788.0
MMS2_k127_128543_8 AAA domain K02224 - 6.3.5.11,6.3.5.9 1.503e-234 733.0
MMS2_k127_128543_9 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 3.083e-234 729.0
MMS2_k127_1293076_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1639.0
MMS2_k127_1293076_1 ABC transporter K06020 - 3.6.3.25 3.134e-320 984.0
MMS2_k127_1293076_10 Protein of unknown function (DUF3240) - - - 0.0000000000000000000000000000000000000000002736 159.0
MMS2_k127_1293076_11 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000003492 163.0
MMS2_k127_1293076_2 Diguanylate cyclase - - - 6.006e-254 821.0
MMS2_k127_1293076_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 503.0
MMS2_k127_1293076_4 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 484.0
MMS2_k127_1293076_5 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 443.0
MMS2_k127_1293076_6 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 421.0
MMS2_k127_1293076_7 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 389.0
MMS2_k127_1293076_8 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 307.0
MMS2_k127_1293076_9 PFAM PEBP family protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000009344 217.0
MMS2_k127_1315240_0 RNB K01147 - 3.1.13.1 1e-323 998.0
MMS2_k127_1315240_1 phosphate-selective porin O and P - - - 1.184e-201 636.0
MMS2_k127_1315240_2 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 542.0
MMS2_k127_1315240_3 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 426.0
MMS2_k127_1315240_4 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 359.0
MMS2_k127_1315240_5 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 336.0
MMS2_k127_1315240_6 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 312.0
MMS2_k127_1315240_7 lipoprotein - - - 0.000000000000000000000005603 103.0
MMS2_k127_1315240_8 - - - - 0.000000144 57.0
MMS2_k127_1519024_0 Threonine synthase N terminus K01733 - 4.2.3.1 1.229e-261 810.0
MMS2_k127_1519024_1 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 5.085e-241 748.0
MMS2_k127_1519024_2 Homoserine dehydrogenase K00003 - 1.1.1.3 6.408e-230 717.0
MMS2_k127_1519024_3 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000166 162.0
MMS2_k127_1522842_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1371.0
MMS2_k127_1522842_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1163.0
MMS2_k127_1522842_10 PFAM TrkA-N domain protein K03499 - - 4.643e-229 716.0
MMS2_k127_1522842_11 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 3.776e-226 706.0
MMS2_k127_1522842_12 Amidohydrolase family K01465 - 3.5.2.3 3.275e-219 691.0
MMS2_k127_1522842_13 Sulfate adenylyltransferase K00957 - 2.7.7.4 3.841e-194 616.0
MMS2_k127_1522842_14 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 598.0
MMS2_k127_1522842_15 histidine kinase HAMP region domain protein K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 599.0
MMS2_k127_1522842_16 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 569.0
MMS2_k127_1522842_17 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 569.0
MMS2_k127_1522842_18 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 530.0
MMS2_k127_1522842_19 AraC Family K07506,K13652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 466.0
MMS2_k127_1522842_2 Histidine kinase K02487,K06596 - - 0.0 1086.0
MMS2_k127_1522842_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 431.0
MMS2_k127_1522842_21 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 424.0
MMS2_k127_1522842_22 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 385.0
MMS2_k127_1522842_23 Inositol monophosphatase family K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 379.0
MMS2_k127_1522842_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 353.0
MMS2_k127_1522842_25 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 346.0
MMS2_k127_1522842_26 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 326.0
MMS2_k127_1522842_27 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 315.0
MMS2_k127_1522842_28 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 313.0
MMS2_k127_1522842_29 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 308.0
MMS2_k127_1522842_3 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1065.0
MMS2_k127_1522842_30 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 317.0
MMS2_k127_1522842_31 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 295.0
MMS2_k127_1522842_32 Phytochelatin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 289.0
MMS2_k127_1522842_33 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000002155 256.0
MMS2_k127_1522842_34 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000006578 243.0
MMS2_k127_1522842_35 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000000002167 231.0
MMS2_k127_1522842_36 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000001465 220.0
MMS2_k127_1522842_37 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000003435 220.0
MMS2_k127_1522842_38 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000009684 199.0
MMS2_k127_1522842_39 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000000000000000000000000008788 199.0
MMS2_k127_1522842_4 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 4.867e-290 897.0
MMS2_k127_1522842_40 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000001401 193.0
MMS2_k127_1522842_41 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000001904 175.0
MMS2_k127_1522842_42 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000001457 165.0
MMS2_k127_1522842_43 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000001322 166.0
MMS2_k127_1522842_44 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000000000001244 162.0
MMS2_k127_1522842_45 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000005772 154.0
MMS2_k127_1522842_46 Pfam Glutaredoxin - - - 0.0000000000000000000000000000000000002197 147.0
MMS2_k127_1522842_47 Protein of unknown function (DUF2288) - - - 0.000000000000000000000000000000001141 132.0
MMS2_k127_1522842_48 Mitomycin resistance protein K07343 - - 0.0000000000000000000000000000008281 125.0
MMS2_k127_1522842_49 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000001951 111.0
MMS2_k127_1522842_5 glutamine synthetase K01915 - 6.3.1.2 2.623e-281 867.0
MMS2_k127_1522842_50 - - - - 0.00000000000000000000000002343 113.0
MMS2_k127_1522842_6 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 3.634e-280 877.0
MMS2_k127_1522842_7 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.506e-254 790.0
MMS2_k127_1522842_8 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 4.673e-254 788.0
MMS2_k127_1522842_9 Polyphosphate kinase 2 (PPK2) - - - 6.044e-252 784.0
MMS2_k127_153046_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 9.634e-208 647.0
MMS2_k127_153046_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 518.0
MMS2_k127_153046_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 364.0
MMS2_k127_153046_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 287.0
MMS2_k127_153046_4 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 289.0
MMS2_k127_153046_5 Von willebrand factor, type a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003408 251.0
MMS2_k127_153046_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000006454 164.0
MMS2_k127_153046_7 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000000000006731 166.0
MMS2_k127_1590_0 AcrB/AcrD/AcrF family K18303 - - 0.0 1265.0
MMS2_k127_1590_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.353e-250 774.0
MMS2_k127_1590_10 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 314.0
MMS2_k127_1590_11 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 310.0
MMS2_k127_1590_12 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 301.0
MMS2_k127_1590_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 279.0
MMS2_k127_1590_14 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000002689 252.0
MMS2_k127_1590_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000008225 250.0
MMS2_k127_1590_16 Protein of unknown function (DUF615) K09889 - - 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
MMS2_k127_1590_17 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000002188 199.0
MMS2_k127_1590_18 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000195 186.0
MMS2_k127_1590_19 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000308 188.0
MMS2_k127_1590_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 3.623e-213 670.0
MMS2_k127_1590_20 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000000000000000000000001167 174.0
MMS2_k127_1590_21 Ion transport protein K10716 - - 0.000000000002452 69.0
MMS2_k127_1590_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 610.0
MMS2_k127_1590_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 530.0
MMS2_k127_1590_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 505.0
MMS2_k127_1590_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 466.0
MMS2_k127_1590_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 446.0
MMS2_k127_1590_8 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 360.0
MMS2_k127_1590_9 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 337.0
MMS2_k127_1593056_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 2.196e-197 625.0
MMS2_k127_1593056_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 544.0
MMS2_k127_1593056_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 451.0
MMS2_k127_1593056_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000000000002542 210.0
MMS2_k127_1593056_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000003099 162.0
MMS2_k127_1593056_5 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000004877 156.0
MMS2_k127_1593056_6 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000005277 134.0
MMS2_k127_1625394_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1830.0
MMS2_k127_1625394_1 Histidine Phosphotransfer domain - - - 1.986e-209 692.0
MMS2_k127_1625394_10 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 331.0
MMS2_k127_1625394_11 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 315.0
MMS2_k127_1625394_12 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 288.0
MMS2_k127_1625394_13 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002046 271.0
MMS2_k127_1625394_14 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001539 263.0
MMS2_k127_1625394_15 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002016 263.0
MMS2_k127_1625394_16 Ferredoxin 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000000002038 195.0
MMS2_k127_1625394_17 PFAM HPP family protein K07168 - - 0.0000000000000000000000000000000000000000000000000000008534 201.0
MMS2_k127_1625394_18 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.000000000000000000000000000000000000000002366 159.0
MMS2_k127_1625394_19 response to cobalt ion - - - 0.000000000000000000000000000000000000000006358 164.0
MMS2_k127_1625394_2 Major Facilitator Superfamily - - - 9.439e-205 645.0
MMS2_k127_1625394_20 Protein of unknown function (DUF2905) - - - 0.00000000000000000000000003407 111.0
MMS2_k127_1625394_21 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000009215 107.0
MMS2_k127_1625394_22 gag-polyprotein putative aspartyl protease K06985 - - 0.0000001547 60.0
MMS2_k127_1625394_3 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 7.931e-202 631.0
MMS2_k127_1625394_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 479.0
MMS2_k127_1625394_5 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 446.0
MMS2_k127_1625394_6 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 436.0
MMS2_k127_1625394_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 400.0
MMS2_k127_1625394_8 Protein of unknown function (DUF3050) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 362.0
MMS2_k127_1625394_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 348.0
MMS2_k127_1676258_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1671.0
MMS2_k127_1676258_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1192.0
MMS2_k127_1676258_10 PFAM ATP-binding region ATPase domain protein - - - 1.237e-198 636.0
MMS2_k127_1676258_11 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 616.0
MMS2_k127_1676258_12 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 562.0
MMS2_k127_1676258_13 AAA domain K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 487.0
MMS2_k127_1676258_14 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 472.0
MMS2_k127_1676258_15 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 482.0
MMS2_k127_1676258_16 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 456.0
MMS2_k127_1676258_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 454.0
MMS2_k127_1676258_18 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 447.0
MMS2_k127_1676258_19 Pilus assembly protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 411.0
MMS2_k127_1676258_2 type II secretion system protein E K02454,K02652,K12276 - - 6.147e-258 805.0
MMS2_k127_1676258_20 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 353.0
MMS2_k127_1676258_21 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
MMS2_k127_1676258_22 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 297.0
MMS2_k127_1676258_23 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 291.0
MMS2_k127_1676258_24 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002159 275.0
MMS2_k127_1676258_25 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002999 269.0
MMS2_k127_1676258_26 Fimbrial assembly protein (PilN) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 264.0
MMS2_k127_1676258_27 carbon utilization K12280 - - 0.000000000000000000000000000000000000000000000000000000000000000000002683 245.0
MMS2_k127_1676258_28 Prokaryotic N-terminal methylation motif K12285 - - 0.000000000000000000000000000000000000000000000000000000000000000001275 238.0
MMS2_k127_1676258_29 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000001803 227.0
MMS2_k127_1676258_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 8.22e-256 796.0
MMS2_k127_1676258_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
MMS2_k127_1676258_31 Tetratricopeptide repeat K12284 - - 0.0000000000000000000000000000000000000000000000000000000000256 220.0
MMS2_k127_1676258_32 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000003744 207.0
MMS2_k127_1676258_33 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000001002 199.0
MMS2_k127_1676258_34 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000008523 192.0
MMS2_k127_1676258_35 - - - - 0.000000000000000000000000000000000000000000000000001475 185.0
MMS2_k127_1676258_36 general secretion pathway protein K02456,K02457,K02458,K10930,K12285 - - 0.0000000000000000000000000000000000000000000000009624 181.0
MMS2_k127_1676258_37 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000006031 159.0
MMS2_k127_1676258_38 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000005954 157.0
MMS2_k127_1676258_39 - - - - 0.00000000000000000000000000000000000000009651 158.0
MMS2_k127_1676258_4 MgsA AAA+ ATPase C terminal K07478 - - 3.721e-245 761.0
MMS2_k127_1676258_40 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000000000000003478 150.0
MMS2_k127_1676258_41 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000003291 145.0
MMS2_k127_1676258_42 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000122 121.0
MMS2_k127_1676258_43 Prokaryotic N-terminal methylation motif K10926 - - 0.0000000000000000000000000003488 121.0
MMS2_k127_1676258_44 general secretion pathway protein K02458,K10924,K10925 - - 0.000000000000000000000000001658 116.0
MMS2_k127_1676258_45 type II secretion system protein K K12286 - - 0.0000000000000000000561 94.0
MMS2_k127_1676258_46 - K12281 - - 0.000000000000000002628 90.0
MMS2_k127_1676258_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.246e-218 684.0
MMS2_k127_1676258_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 8.913e-218 683.0
MMS2_k127_1676258_7 Virulence factor membrane-bound polymerase, C-terminal - - - 7.282e-207 659.0
MMS2_k127_1676258_8 PFAM type II and III secretion system protein K02453,K12282 - - 3.892e-206 655.0
MMS2_k127_1676258_9 PFAM Type II secretion system F domain K02455,K12278 - - 9.307e-202 634.0
MMS2_k127_1725331_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0 1056.0
MMS2_k127_1725331_1 V-type ATPase 116kDa subunit family K02123 - - 2.001e-319 987.0
MMS2_k127_1725331_2 ATP synthase (C/AC39) subunit K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 494.0
MMS2_k127_1725331_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 380.0
MMS2_k127_1725331_4 ATP synthase subunit C K02124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001455 246.0
MMS2_k127_1725331_5 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000001656 222.0
MMS2_k127_1725331_6 V-type proton ATPase subunit E K02121 - - 0.000000000000000000000000000000000000000000000000001087 193.0
MMS2_k127_1725331_7 ATP synthase (F/14-kDa) subunit - - - 0.0000000000000000000000000000000000000000008794 165.0
MMS2_k127_1725331_8 - - - - 0.000000000000000000000000000004194 123.0
MMS2_k127_1725331_9 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000003223 121.0
MMS2_k127_1757884_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1348.0
MMS2_k127_1757884_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.497e-232 722.0
MMS2_k127_1757884_10 3'-5' exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 286.0
MMS2_k127_1757884_11 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000000004914 232.0
MMS2_k127_1757884_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
MMS2_k127_1757884_13 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000246 226.0
MMS2_k127_1757884_14 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000000000000001019 190.0
MMS2_k127_1757884_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000005066 143.0
MMS2_k127_1757884_16 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000001074 91.0
MMS2_k127_1757884_2 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 590.0
MMS2_k127_1757884_3 Chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 586.0
MMS2_k127_1757884_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 543.0
MMS2_k127_1757884_5 glycosyl - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 531.0
MMS2_k127_1757884_6 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 489.0
MMS2_k127_1757884_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 465.0
MMS2_k127_1757884_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 442.0
MMS2_k127_1757884_9 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 356.0
MMS2_k127_1875660_0 PFAM type II secretion system protein E K02670 - - 4.406e-216 674.0
MMS2_k127_1875660_1 PFAM type II secretion system protein E K02669,K12203 - - 2.304e-211 659.0
MMS2_k127_1875660_2 THUMP K07444 - - 1.174e-197 622.0
MMS2_k127_1875660_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 336.0
MMS2_k127_1875660_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 326.0
MMS2_k127_1875660_5 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 291.0
MMS2_k127_1875660_6 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000000000005425 216.0
MMS2_k127_1875660_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000001265 175.0
MMS2_k127_1875660_8 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000005436 172.0
MMS2_k127_2048885_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 552.0
MMS2_k127_2048885_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 483.0
MMS2_k127_2048885_2 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 369.0
MMS2_k127_2048885_3 cell adhesion involved in biofilm formation K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 343.0
MMS2_k127_2048885_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 323.0
MMS2_k127_2048885_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 281.0
MMS2_k127_2048885_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000001507 151.0
MMS2_k127_2048885_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000002897 91.0
MMS2_k127_2303741_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1295.0
MMS2_k127_2303741_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 294.0
MMS2_k127_2303741_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000005818 232.0
MMS2_k127_2303741_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000006348 185.0
MMS2_k127_2303741_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000004883 86.0
MMS2_k127_2404172_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.395e-258 799.0
MMS2_k127_2404172_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 599.0
MMS2_k127_2404172_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000006669 175.0
MMS2_k127_2404172_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000005231 140.0
MMS2_k127_2404172_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000028 132.0
MMS2_k127_245290_0 Arsenite-activated ATPase (ArsA) K01551 - 3.6.3.16 1.749e-268 839.0
MMS2_k127_245290_1 Soluble lytic murein transglycosylase L domain K08309 - - 5.774e-238 752.0
MMS2_k127_245290_10 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 317.0
MMS2_k127_245290_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 293.0
MMS2_k127_245290_12 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002225 269.0
MMS2_k127_245290_13 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000006398 248.0
MMS2_k127_245290_14 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000002015 239.0
MMS2_k127_245290_15 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000002939 237.0
MMS2_k127_245290_16 SMART CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000003318 212.0
MMS2_k127_245290_17 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000000000000000000000000000000000000000005013 209.0
MMS2_k127_245290_18 Universal stress protein - - - 0.00000000000000000000000000000000000000000000004928 176.0
MMS2_k127_245290_19 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000003777 169.0
MMS2_k127_245290_2 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 2.972e-205 644.0
MMS2_k127_245290_20 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000005789 127.0
MMS2_k127_245290_21 - - - - 0.00000000000000000000000000006958 118.0
MMS2_k127_245290_22 SMART Calcium-binding EF-hand-containing protein - - - 0.0000000000000000000000007905 109.0
MMS2_k127_245290_3 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 596.0
MMS2_k127_245290_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 533.0
MMS2_k127_245290_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 535.0
MMS2_k127_245290_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 440.0
MMS2_k127_245290_7 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 422.0
MMS2_k127_245290_8 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 414.0
MMS2_k127_245290_9 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 341.0
MMS2_k127_2453362_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1357.0
MMS2_k127_2453362_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1315.0
MMS2_k127_2453362_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 332.0
MMS2_k127_2453362_11 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000007315 196.0
MMS2_k127_2453362_12 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000000000000000000000000004567 141.0
MMS2_k127_2453362_13 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000001545 130.0
MMS2_k127_2453362_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0 1037.0
MMS2_k127_2453362_3 metal-dependent phosphohydrolase HD sub domain - - - 3.183e-244 764.0
MMS2_k127_2453362_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 552.0
MMS2_k127_2453362_5 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 548.0
MMS2_k127_2453362_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 431.0
MMS2_k127_2453362_7 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 431.0
MMS2_k127_2453362_8 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 409.0
MMS2_k127_2453362_9 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 354.0
MMS2_k127_2532034_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2635.0
MMS2_k127_2532034_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1137.0
MMS2_k127_2532034_10 Cytochrome b(N-terminal)/b6/petB K00412 - - 1.707e-229 714.0
MMS2_k127_2532034_11 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 6.583e-228 713.0
MMS2_k127_2532034_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 2.209e-218 679.0
MMS2_k127_2532034_13 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 1.967e-213 665.0
MMS2_k127_2532034_14 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 606.0
MMS2_k127_2532034_15 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 580.0
MMS2_k127_2532034_16 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 580.0
MMS2_k127_2532034_17 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 575.0
MMS2_k127_2532034_18 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 563.0
MMS2_k127_2532034_19 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 365.0
MMS2_k127_2532034_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0 1011.0
MMS2_k127_2532034_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 363.0
MMS2_k127_2532034_21 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 338.0
MMS2_k127_2532034_22 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 312.0
MMS2_k127_2532034_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002482 278.0
MMS2_k127_2532034_24 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005458 264.0
MMS2_k127_2532034_25 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 262.0
MMS2_k127_2532034_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001517 265.0
MMS2_k127_2532034_27 DSBA-like thioredoxin domain K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 264.0
MMS2_k127_2532034_28 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008656 263.0
MMS2_k127_2532034_29 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007225 254.0
MMS2_k127_2532034_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.038e-301 936.0
MMS2_k127_2532034_30 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 258.0
MMS2_k127_2532034_31 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
MMS2_k127_2532034_32 Sporulation related domain - - - 0.00000000000000000000000000000000000000005357 158.0
MMS2_k127_2532034_33 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000002559 145.0
MMS2_k127_2532034_34 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000004003 79.0
MMS2_k127_2532034_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.405e-291 897.0
MMS2_k127_2532034_5 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 3.612e-291 896.0
MMS2_k127_2532034_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.002e-271 850.0
MMS2_k127_2532034_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.549e-266 824.0
MMS2_k127_2532034_8 Aminotransferase class-III K01845 - 5.4.3.8 2.687e-252 784.0
MMS2_k127_2532034_9 PFAM type II and III secretion system protein K02666 - - 8.297e-231 734.0
MMS2_k127_2538897_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 421.0
MMS2_k127_2538897_1 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 411.0
MMS2_k127_2538897_2 Flavodoxin domain K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 298.0
MMS2_k127_2538897_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000002506 222.0
MMS2_k127_2538897_4 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000000000005381 215.0
MMS2_k127_2538897_5 - - - - 0.000001229 52.0
MMS2_k127_2636739_0 GDP-mannose 4,6 dehydratase - - - 5.951e-216 672.0
MMS2_k127_2636739_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 595.0
MMS2_k127_2636739_2 isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007532 278.0
MMS2_k127_2636739_3 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
MMS2_k127_2667877_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0 1063.0
MMS2_k127_2667877_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 4.973e-313 977.0
MMS2_k127_2667877_10 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 331.0
MMS2_k127_2667877_11 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 316.0
MMS2_k127_2667877_12 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000352 278.0
MMS2_k127_2667877_13 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005089 261.0
MMS2_k127_2667877_14 Protein of unknown function (DUF1134) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006553 251.0
MMS2_k127_2667877_15 - - - - 0.00000000000000000000000000000000000000000000000000000000002196 209.0
MMS2_k127_2667877_16 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000002595 184.0
MMS2_k127_2667877_17 HupE / UreJ protein K03192 - - 0.00000000000000000000000000000000000000000000004063 176.0
MMS2_k127_2667877_18 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000006078 169.0
MMS2_k127_2667877_19 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000001423 131.0
MMS2_k127_2667877_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 2.222e-282 878.0
MMS2_k127_2667877_20 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000003515 106.0
MMS2_k127_2667877_21 HupH hydrogenase expression protein, C-terminal conserved region - - - 0.000000000000000000002242 100.0
MMS2_k127_2667877_22 - - - - 0.000000000000415 70.0
MMS2_k127_2667877_25 Thioredoxin K05838 - - 0.000000004782 63.0
MMS2_k127_2667877_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.841e-271 839.0
MMS2_k127_2667877_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 3.716e-212 671.0
MMS2_k127_2667877_5 Oxidoreductase FAD-binding domain protein K00523,K18248 - 1.17.1.1 7.793e-202 639.0
MMS2_k127_2667877_6 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 552.0
MMS2_k127_2667877_7 4 iron, 4 sulfur cluster binding K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 467.0
MMS2_k127_2667877_8 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 384.0
MMS2_k127_2667877_9 May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 352.0
MMS2_k127_2761436_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.902e-246 766.0
MMS2_k127_2761436_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 1.499e-194 612.0
MMS2_k127_2761436_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 512.0
MMS2_k127_2761436_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001731 264.0
MMS2_k127_2761436_4 PFAM FecR protein - - - 0.0000000000000000000000000000000000000002829 168.0
MMS2_k127_2761436_5 PFAM FecR protein - - - 0.000000000000000000000000000000000003853 155.0
MMS2_k127_2761436_6 PFAM FecR protein - - - 0.0000004386 61.0
MMS2_k127_2847174_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1853.0
MMS2_k127_2847174_1 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 0.0 1299.0
MMS2_k127_2847174_10 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 550.0
MMS2_k127_2847174_11 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 546.0
MMS2_k127_2847174_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 501.0
MMS2_k127_2847174_13 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 495.0
MMS2_k127_2847174_14 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 487.0
MMS2_k127_2847174_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 469.0
MMS2_k127_2847174_16 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 420.0
MMS2_k127_2847174_17 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 400.0
MMS2_k127_2847174_18 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 377.0
MMS2_k127_2847174_19 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 358.0
MMS2_k127_2847174_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.929e-288 902.0
MMS2_k127_2847174_20 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 341.0
MMS2_k127_2847174_21 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 319.0
MMS2_k127_2847174_22 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 319.0
MMS2_k127_2847174_23 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 306.0
MMS2_k127_2847174_24 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 309.0
MMS2_k127_2847174_25 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005134 274.0
MMS2_k127_2847174_26 helix_turn_helix, Lux Regulon K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003875 276.0
MMS2_k127_2847174_27 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002575 258.0
MMS2_k127_2847174_28 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002652 248.0
MMS2_k127_2847174_29 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002789 245.0
MMS2_k127_2847174_3 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 3.553e-267 824.0
MMS2_k127_2847174_30 PFAM UspA domain protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000006112 244.0
MMS2_k127_2847174_31 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000000000000000000007458 231.0
MMS2_k127_2847174_32 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009745 246.0
MMS2_k127_2847174_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000211 230.0
MMS2_k127_2847174_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003481 224.0
MMS2_k127_2847174_35 DsrE/DsrF-like family K07236 - - 0.000000000000000000000000000000000000000000000000000000000002622 209.0
MMS2_k127_2847174_36 Domain of unknown function (DUF4279) - - - 0.00000000000000000000000000000000000000000000000000000000003682 210.0
MMS2_k127_2847174_37 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000003647 185.0
MMS2_k127_2847174_38 response regulator K13041 - - 0.0000000000000000000000000000000000000000000000000009453 192.0
MMS2_k127_2847174_39 Cas6 Crispr - - - 0.000000000000000000000000000000000000000000000000001287 190.0
MMS2_k127_2847174_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 9.93e-240 744.0
MMS2_k127_2847174_40 DsrH like protein K07237 - - 0.00000000000000000000000000000000000000701 146.0
MMS2_k127_2847174_41 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000002441 149.0
MMS2_k127_2847174_42 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000000005035 127.0
MMS2_k127_2847174_43 - - - - 0.00000000000000000000000000000144 126.0
MMS2_k127_2847174_45 - - - - 0.000000000000000000000000008706 110.0
MMS2_k127_2847174_46 - - - - 0.0000000000000009818 83.0
MMS2_k127_2847174_47 DsrC like protein K11179 - - 0.0000002462 52.0
MMS2_k127_2847174_48 4Fe-4S dicluster domain - - - 0.00003188 47.0
MMS2_k127_2847174_5 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 4.034e-233 721.0
MMS2_k127_2847174_6 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.022e-232 724.0
MMS2_k127_2847174_7 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 1.903e-199 632.0
MMS2_k127_2847174_8 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 567.0
MMS2_k127_2847174_9 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 570.0
MMS2_k127_285147_0 PFAM Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0 1041.0
MMS2_k127_285147_1 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 8.355e-312 958.0
MMS2_k127_285147_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007396 258.0
MMS2_k127_285147_11 PFAM porin Gram-negative type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001116 255.0
MMS2_k127_285147_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000002885 244.0
MMS2_k127_285147_13 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000001557 221.0
MMS2_k127_285147_14 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000562 208.0
MMS2_k127_285147_15 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000002319 182.0
MMS2_k127_285147_16 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000000000002981 172.0
MMS2_k127_285147_17 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000359 172.0
MMS2_k127_285147_18 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000001445 158.0
MMS2_k127_285147_19 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000001783 151.0
MMS2_k127_285147_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.659e-304 938.0
MMS2_k127_285147_20 Cyd operon protein YbgE (Cyd_oper_YbgE) - - - 0.0000000000000000000000000000000009662 131.0
MMS2_k127_285147_21 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000002569 118.0
MMS2_k127_285147_22 - - - - 0.00000000000000000000006852 98.0
MMS2_k127_285147_24 - - - - 0.0000000000001899 79.0
MMS2_k127_285147_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.968e-288 888.0
MMS2_k127_285147_4 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 9.046e-239 742.0
MMS2_k127_285147_5 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 1.404e-236 736.0
MMS2_k127_285147_6 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 2.23e-223 708.0
MMS2_k127_285147_7 transporter component K07112 - - 1.784e-199 625.0
MMS2_k127_285147_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 572.0
MMS2_k127_285147_9 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 444.0
MMS2_k127_2862993_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1336.0
MMS2_k127_2905641_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1509.0
MMS2_k127_2905641_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 401.0
MMS2_k127_2905641_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 297.0
MMS2_k127_2905641_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000006147 181.0
MMS2_k127_3187266_0 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.0 1299.0
MMS2_k127_3187266_1 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1181.0
MMS2_k127_3187266_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000004108 196.0
MMS2_k127_3187266_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000252 154.0
MMS2_k127_3187266_4 Cold shock K03704 - - 0.00000000000000000000000000000000002064 135.0
MMS2_k127_3223071_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1086.0
MMS2_k127_3223071_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.237e-305 947.0
MMS2_k127_3223071_10 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 447.0
MMS2_k127_3223071_11 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 428.0
MMS2_k127_3223071_12 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 420.0
MMS2_k127_3223071_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 423.0
MMS2_k127_3223071_14 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 414.0
MMS2_k127_3223071_15 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 389.0
MMS2_k127_3223071_16 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 374.0
MMS2_k127_3223071_17 TIGRFAM RNA polymerase sigma factor RpoE K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 351.0
MMS2_k127_3223071_18 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 357.0
MMS2_k127_3223071_19 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 356.0
MMS2_k127_3223071_2 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 3.468e-248 777.0
MMS2_k127_3223071_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 331.0
MMS2_k127_3223071_21 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 332.0
MMS2_k127_3223071_22 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 282.0
MMS2_k127_3223071_23 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006032 275.0
MMS2_k127_3223071_24 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002446 251.0
MMS2_k127_3223071_25 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000000000000000000000000000000000004202 191.0
MMS2_k127_3223071_26 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000003905 166.0
MMS2_k127_3223071_27 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000006104 145.0
MMS2_k127_3223071_28 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000000000003708 131.0
MMS2_k127_3223071_29 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000000000000000000000000003555 124.0
MMS2_k127_3223071_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 3.232e-219 685.0
MMS2_k127_3223071_30 - - - - 0.000000000000000000005283 98.0
MMS2_k127_3223071_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 3.611e-219 689.0
MMS2_k127_3223071_5 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 614.0
MMS2_k127_3223071_6 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 606.0
MMS2_k127_3223071_7 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 503.0
MMS2_k127_3223071_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
MMS2_k127_3223071_9 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 457.0
MMS2_k127_3249394_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 9.614e-318 979.0
MMS2_k127_3249394_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.128e-313 970.0
MMS2_k127_3249394_10 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 476.0
MMS2_k127_3249394_11 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 431.0
MMS2_k127_3249394_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 425.0
MMS2_k127_3249394_13 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 408.0
MMS2_k127_3249394_14 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 420.0
MMS2_k127_3249394_15 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 359.0
MMS2_k127_3249394_16 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
MMS2_k127_3249394_17 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 341.0
MMS2_k127_3249394_18 Nitroreductase family K19286 - 1.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 297.0
MMS2_k127_3249394_2 serine protease K07403 - - 4.865e-203 642.0
MMS2_k127_3249394_20 Protein of unknown function, DUF481 K07283 - - 0.00000000000000000000000000000000000000000000002036 180.0
MMS2_k127_3249394_21 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000435 167.0
MMS2_k127_3249394_22 OsmC-like protein - - - 0.000000000000000000000000000000000000001035 152.0
MMS2_k127_3249394_23 Domain of unknown function (DUF5062) - - - 0.000000000000000000000000000000000000006802 147.0
MMS2_k127_3249394_24 LysR substrate binding domain K13634 - - 0.0000000000000000000000000002248 115.0
MMS2_k127_3249394_25 diguanylate cyclase - - - 0.0000000000000000000000000006896 124.0
MMS2_k127_3249394_26 Pfam:DUF1049 K08992 - - 0.0000000000000000000000005871 106.0
MMS2_k127_3249394_27 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000001264 109.0
MMS2_k127_3249394_28 - - - - 0.0000000000009754 74.0
MMS2_k127_3249394_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 8.481e-202 635.0
MMS2_k127_3249394_30 - - - - 0.0000000002001 66.0
MMS2_k127_3249394_4 NeuB family K03856 - 2.5.1.54 9.363e-197 615.0
MMS2_k127_3249394_5 Pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 596.0
MMS2_k127_3249394_6 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 563.0
MMS2_k127_3249394_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 559.0
MMS2_k127_3249394_8 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 525.0
MMS2_k127_3249394_9 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
MMS2_k127_3304412_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.084e-272 843.0
MMS2_k127_3304412_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.381e-253 782.0
MMS2_k127_3304412_10 Protein of unknown function (DUF3579) - - - 0.000000000000000000000001576 114.0
MMS2_k127_3304412_11 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000002483 94.0
MMS2_k127_3304412_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 2.765e-202 635.0
MMS2_k127_3304412_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 581.0
MMS2_k127_3304412_4 Transcriptional regulator, LysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 430.0
MMS2_k127_3304412_5 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 328.0
MMS2_k127_3304412_6 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007126 274.0
MMS2_k127_3304412_7 DJ-1/PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 254.0
MMS2_k127_3304412_8 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000000000000944 213.0
MMS2_k127_3304412_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000005277 134.0
MMS2_k127_3351286_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1169.0
MMS2_k127_3351286_1 FtsX-like permease family K02004 - - 0.0 1038.0
MMS2_k127_3351286_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 349.0
MMS2_k127_3351286_11 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 321.0
MMS2_k127_3351286_12 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 308.0
MMS2_k127_3351286_13 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
MMS2_k127_3351286_14 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 271.0
MMS2_k127_3351286_15 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001608 273.0
MMS2_k127_3351286_16 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006521 258.0
MMS2_k127_3351286_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003078 250.0
MMS2_k127_3351286_18 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004525 265.0
MMS2_k127_3351286_19 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000112 248.0
MMS2_k127_3351286_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1036.0
MMS2_k127_3351286_20 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000001778 247.0
MMS2_k127_3351286_21 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000001444 224.0
MMS2_k127_3351286_3 PFAM aminotransferase class I and II K00812 - 2.6.1.1 4.602e-223 705.0
MMS2_k127_3351286_4 RmuC family K09760 - - 8.822e-211 661.0
MMS2_k127_3351286_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 511.0
MMS2_k127_3351286_6 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 499.0
MMS2_k127_3351286_7 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 501.0
MMS2_k127_3351286_8 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 520.0
MMS2_k127_3351286_9 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 479.0
MMS2_k127_3369406_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 6e-323 1004.0
MMS2_k127_3369406_1 S-adenosyl-L-methionine-dependent methyltransferase K15461 - 2.1.1.61 2.026e-270 843.0
MMS2_k127_3369406_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 494.0
MMS2_k127_3369406_11 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 456.0
MMS2_k127_3369406_12 PFAM ABC transporter related K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 456.0
MMS2_k127_3369406_13 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 456.0
MMS2_k127_3369406_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 423.0
MMS2_k127_3369406_15 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 419.0
MMS2_k127_3369406_16 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 420.0
MMS2_k127_3369406_17 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 419.0
MMS2_k127_3369406_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 412.0
MMS2_k127_3369406_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 394.0
MMS2_k127_3369406_2 Circularly permuted ATP-grasp type 2 - - - 1.178e-255 795.0
MMS2_k127_3369406_20 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 389.0
MMS2_k127_3369406_21 PFAM 20S proteasome, A and B subunits K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 379.0
MMS2_k127_3369406_22 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 356.0
MMS2_k127_3369406_23 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 336.0
MMS2_k127_3369406_24 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 333.0
MMS2_k127_3369406_25 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 325.0
MMS2_k127_3369406_26 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
MMS2_k127_3369406_27 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 304.0
MMS2_k127_3369406_28 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 282.0
MMS2_k127_3369406_29 Peptidase S24-like K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002713 278.0
MMS2_k127_3369406_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 5.841e-238 738.0
MMS2_k127_3369406_30 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004441 278.0
MMS2_k127_3369406_31 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003942 272.0
MMS2_k127_3369406_32 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005369 256.0
MMS2_k127_3369406_33 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008488 253.0
MMS2_k127_3369406_34 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000008589 250.0
MMS2_k127_3369406_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007865 244.0
MMS2_k127_3369406_36 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000001077 242.0
MMS2_k127_3369406_37 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
MMS2_k127_3369406_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000385 231.0
MMS2_k127_3369406_39 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000008121 230.0
MMS2_k127_3369406_4 Belongs to the UPF0061 (SELO) family - - - 9.943e-221 693.0
MMS2_k127_3369406_40 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000009193 228.0
MMS2_k127_3369406_41 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
MMS2_k127_3369406_42 - - - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
MMS2_k127_3369406_43 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000009476 204.0
MMS2_k127_3369406_44 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
MMS2_k127_3369406_45 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000000000000005875 198.0
MMS2_k127_3369406_46 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000001033 189.0
MMS2_k127_3369406_47 KTSC domain - - - 0.00000000000000000000000000000000000000000002167 164.0
MMS2_k127_3369406_48 - - - - 0.0000000000000000000000000000000000000012 150.0
MMS2_k127_3369406_49 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000000000001497 151.0
MMS2_k127_3369406_5 SMART PDZ DHR GLGF domain protein K11749 - - 1.325e-198 629.0
MMS2_k127_3369406_50 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000001004 122.0
MMS2_k127_3369406_51 - - - - 0.0000000000000000000000000000785 120.0
MMS2_k127_3369406_52 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000189 117.0
MMS2_k127_3369406_53 - - - - 0.000000000000000000002627 95.0
MMS2_k127_3369406_54 Transcription factor zinc-finger K09981 - - 0.00000000001555 66.0
MMS2_k127_3369406_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 4.993e-198 623.0
MMS2_k127_3369406_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 577.0
MMS2_k127_3369406_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 550.0
MMS2_k127_3369406_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 499.0
MMS2_k127_3378541_0 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.466e-223 696.0
MMS2_k127_3378541_1 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 586.0
MMS2_k127_3378541_2 4 iron, 4 sulfur cluster binding K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 571.0
MMS2_k127_3378541_3 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 551.0
MMS2_k127_3378541_4 PFAM FAD linked oxidase domain protein K00104,K11472 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 484.0
MMS2_k127_3378541_5 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 417.0
MMS2_k127_3378541_6 periplasmic secreted protein - - - 0.000000000000000000000000000000000000002197 164.0
MMS2_k127_3378541_7 Threonine synthase N terminus K01733 - 4.2.3.1 0.00000000000000000000000002911 108.0
MMS2_k127_3531306_0 PFAM polysaccharide biosynthesis protein CapD - - - 6.688e-285 886.0
MMS2_k127_3531306_1 Class II Aldolase and Adducin N-terminal domain - - - 7.437e-247 771.0
MMS2_k127_3531306_10 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
MMS2_k127_3531306_11 PFAM Glycosyl transferase, family 4, conserved region K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 432.0
MMS2_k127_3531306_12 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 425.0
MMS2_k127_3531306_13 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 390.0
MMS2_k127_3531306_14 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
MMS2_k127_3531306_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 369.0
MMS2_k127_3531306_16 heptosyltransferase K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 355.0
MMS2_k127_3531306_17 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 336.0
MMS2_k127_3531306_18 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 330.0
MMS2_k127_3531306_19 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 323.0
MMS2_k127_3531306_2 isochorismatase K06901 - - 7.797e-219 689.0
MMS2_k127_3531306_20 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
MMS2_k127_3531306_21 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 293.0
MMS2_k127_3531306_23 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001489 271.0
MMS2_k127_3531306_24 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001914 277.0
MMS2_k127_3531306_25 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000005044 240.0
MMS2_k127_3531306_26 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000002144 175.0
MMS2_k127_3531306_27 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000522 151.0
MMS2_k127_3531306_28 GtrA-like protein - - - 0.00000000000000000000000000212 119.0
MMS2_k127_3531306_29 Methionine biosynthesis protein MetW - - - 0.000000000000000000000007665 111.0
MMS2_k127_3531306_3 HAD-superfamily phosphatase subfamily IIIC - - - 5.45e-203 650.0
MMS2_k127_3531306_30 HEAT repeats - - - 0.00000000000000000002269 95.0
MMS2_k127_3531306_31 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000511 96.0
MMS2_k127_3531306_32 Phosphopantetheine attachment site K02078 - - 0.000000000000000001242 88.0
MMS2_k127_3531306_33 dehydratase - - - 0.0000000000001843 78.0
MMS2_k127_3531306_34 Glycine zipper 2TM domain K06077 - - 0.000000001483 69.0
MMS2_k127_3531306_35 Peptidase family M48 - - - 0.0000593 55.0
MMS2_k127_3531306_4 PFAM membrane bound O-acyl transferase MBOAT family protein - - - 7.706e-200 635.0
MMS2_k127_3531306_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 542.0
MMS2_k127_3531306_6 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 514.0
MMS2_k127_3531306_7 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 512.0
MMS2_k127_3531306_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 497.0
MMS2_k127_3531306_9 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 494.0
MMS2_k127_3533870_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1472.0
MMS2_k127_3533870_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1181.0
MMS2_k127_3533870_10 Putative quorum-sensing-regulated virulence factor K09954 - - 0.0000000000000000000000000000000000002916 141.0
MMS2_k127_3533870_11 Protein of unknown function (DUF2782) - - - 0.00000000000000000000000000000007192 132.0
MMS2_k127_3533870_2 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 538.0
MMS2_k127_3533870_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 502.0
MMS2_k127_3533870_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 410.0
MMS2_k127_3533870_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005565 267.0
MMS2_k127_3533870_6 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 232.0
MMS2_k127_3533870_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000001066 226.0
MMS2_k127_3533870_8 pyrroloquinoline quinone binding K12287 - - 0.00000000000000000000000000000000000000000000000000006072 197.0
MMS2_k127_3533870_9 MEKHLA domain - - - 0.00000000000000000000000000000000000000000000008095 183.0
MMS2_k127_3537402_0 von Willebrand factor (vWF) type A domain - - - 0.0 1270.0
MMS2_k127_3537402_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 9.457e-301 923.0
MMS2_k127_3537402_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 9.368e-217 673.0
MMS2_k127_3537402_3 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 498.0
MMS2_k127_3537402_4 ATPase associated with various cellular activities AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 490.0
MMS2_k127_3537402_5 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 427.0
MMS2_k127_3537402_6 ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
MMS2_k127_3537402_7 SMART von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000002872 169.0
MMS2_k127_3537402_8 - - - - 0.0000000000000000000000000000000000000000006851 158.0
MMS2_k127_3537402_9 - - - - 0.0000000000000000000000000000000008868 134.0
MMS2_k127_3539359_0 Domain of unknown function (DUF3400) - - - 0.0 2019.0
MMS2_k127_3539359_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1075.0
MMS2_k127_3539359_10 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 394.0
MMS2_k127_3539359_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 391.0
MMS2_k127_3539359_12 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 385.0
MMS2_k127_3539359_13 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 385.0
MMS2_k127_3539359_14 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 287.0
MMS2_k127_3539359_15 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001452 278.0
MMS2_k127_3539359_16 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000000000000000000000000000000001991 211.0
MMS2_k127_3539359_17 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000000000000000000000001004 184.0
MMS2_k127_3539359_18 Cell division protein ZapA K09888 - - 0.00000000000000000000000000000000000000000000005899 170.0
MMS2_k127_3539359_19 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000000000000001982 158.0
MMS2_k127_3539359_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.287e-285 887.0
MMS2_k127_3539359_20 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000000000000006037 136.0
MMS2_k127_3539359_22 - - - - 0.000000000002236 72.0
MMS2_k127_3539359_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 3.154e-216 681.0
MMS2_k127_3539359_4 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 595.0
MMS2_k127_3539359_5 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 488.0
MMS2_k127_3539359_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 489.0
MMS2_k127_3539359_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 472.0
MMS2_k127_3539359_8 receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 466.0
MMS2_k127_3539359_9 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 455.0
MMS2_k127_3547649_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1374.0
MMS2_k127_3547649_1 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.217e-280 863.0
MMS2_k127_3547649_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000006696 218.0
MMS2_k127_3547649_11 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000047 206.0
MMS2_k127_3547649_12 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000000000000007747 191.0
MMS2_k127_3547649_13 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000003725 149.0
MMS2_k127_3547649_14 Histone deacetylase domain - - - 0.00000000000000000000000000000000000001047 148.0
MMS2_k127_3547649_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.944e-239 756.0
MMS2_k127_3547649_3 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 5.578e-207 647.0
MMS2_k127_3547649_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 3.768e-203 640.0
MMS2_k127_3547649_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 4.439e-196 615.0
MMS2_k127_3547649_6 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 507.0
MMS2_k127_3547649_7 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 431.0
MMS2_k127_3547649_8 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008939 246.0
MMS2_k127_3547649_9 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
MMS2_k127_3660102_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.895e-234 731.0
MMS2_k127_3660102_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 496.0
MMS2_k127_3660102_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 408.0
MMS2_k127_3660102_3 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 354.0
MMS2_k127_3660102_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 329.0
MMS2_k127_3660102_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000004303 213.0
MMS2_k127_3660102_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000001433 205.0
MMS2_k127_3660102_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000001009 146.0
MMS2_k127_3660102_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000003245 108.0
MMS2_k127_3660102_9 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000001689 97.0
MMS2_k127_3745298_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2484.0
MMS2_k127_3745298_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 452.0
MMS2_k127_3745298_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000005571 188.0
MMS2_k127_3745298_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000002874 186.0
MMS2_k127_3776716_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.972e-273 842.0
MMS2_k127_3776716_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.109e-261 805.0
MMS2_k127_3776716_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 318.0
MMS2_k127_3776716_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 316.0
MMS2_k127_3776716_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003532 266.0
MMS2_k127_3776716_5 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000000000000000000000000000000000002266 151.0
MMS2_k127_3776716_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000001783 105.0
MMS2_k127_3794654_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1510.0
MMS2_k127_3794654_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1200.0
MMS2_k127_3794654_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 400.0
MMS2_k127_3794654_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
MMS2_k127_3794654_12 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 319.0
MMS2_k127_3794654_13 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
MMS2_k127_3794654_14 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 297.0
MMS2_k127_3794654_15 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 287.0
MMS2_k127_3794654_16 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 289.0
MMS2_k127_3794654_17 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000005109 171.0
MMS2_k127_3794654_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000002482 168.0
MMS2_k127_3794654_19 Bacterial protein of unknown function (DUF934) - - - 0.00000000000000000000000000000007637 131.0
MMS2_k127_3794654_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1035.0
MMS2_k127_3794654_20 - - - - 0.0000000000000000000000000001634 123.0
MMS2_k127_3794654_21 - - - - 0.0000000000000001115 84.0
MMS2_k127_3794654_3 Amino acid permease - - - 7.26e-257 807.0
MMS2_k127_3794654_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 7.751e-231 721.0
MMS2_k127_3794654_5 Arsenical pump membrane protein - - - 1.024e-226 709.0
MMS2_k127_3794654_6 MacB-like periplasmic core domain K02004 - - 3.731e-196 618.0
MMS2_k127_3794654_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 571.0
MMS2_k127_3794654_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 526.0
MMS2_k127_3794654_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 473.0
MMS2_k127_3862090_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.0 999.0
MMS2_k127_3862090_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 3.764e-305 942.0
MMS2_k127_3862090_10 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 463.0
MMS2_k127_3862090_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 456.0
MMS2_k127_3862090_12 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 440.0
MMS2_k127_3862090_13 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 407.0
MMS2_k127_3862090_14 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 380.0
MMS2_k127_3862090_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 373.0
MMS2_k127_3862090_16 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 360.0
MMS2_k127_3862090_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 342.0
MMS2_k127_3862090_18 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000127 282.0
MMS2_k127_3862090_19 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004737 252.0
MMS2_k127_3862090_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.148e-241 750.0
MMS2_k127_3862090_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000612 236.0
MMS2_k127_3862090_21 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000006008 242.0
MMS2_k127_3862090_22 - - - - 0.00000000000000000000000000000000000000000000000000000000002161 214.0
MMS2_k127_3862090_23 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000009147 212.0
MMS2_k127_3862090_24 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000003317 126.0
MMS2_k127_3862090_25 PFAM FecR protein - - - 0.0000000000000000000000000003517 123.0
MMS2_k127_3862090_26 - - - - 0.00000000000000000000003728 104.0
MMS2_k127_3862090_27 response to antibiotic K07122 - - 0.0000000000000000001415 91.0
MMS2_k127_3862090_28 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000787 85.0
MMS2_k127_3862090_29 - - - - 0.000000000001937 69.0
MMS2_k127_3862090_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.621e-232 726.0
MMS2_k127_3862090_30 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000007035 57.0
MMS2_k127_3862090_32 - - - - 0.00000462 48.0
MMS2_k127_3862090_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 5.417e-222 692.0
MMS2_k127_3862090_5 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 580.0
MMS2_k127_3862090_6 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 566.0
MMS2_k127_3862090_7 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 542.0
MMS2_k127_3862090_8 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 525.0
MMS2_k127_3862090_9 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 479.0
MMS2_k127_3909299_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.62e-307 943.0
MMS2_k127_3909299_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.553e-297 917.0
MMS2_k127_3909299_10 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 530.0
MMS2_k127_3909299_11 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 527.0
MMS2_k127_3909299_12 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 460.0
MMS2_k127_3909299_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 440.0
MMS2_k127_3909299_14 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 428.0
MMS2_k127_3909299_15 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 376.0
MMS2_k127_3909299_16 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 351.0
MMS2_k127_3909299_17 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 291.0
MMS2_k127_3909299_18 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003067 266.0
MMS2_k127_3909299_19 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002775 231.0
MMS2_k127_3909299_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.872e-292 914.0
MMS2_k127_3909299_20 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000001639 164.0
MMS2_k127_3909299_21 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000005208 162.0
MMS2_k127_3909299_22 OmpA-like transmembrane domain K03286 - - 0.00000000000000000000000000000000003476 140.0
MMS2_k127_3909299_23 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000002791 115.0
MMS2_k127_3909299_24 - - - - 0.0000001122 54.0
MMS2_k127_3909299_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 7.5e-277 854.0
MMS2_k127_3909299_4 Peptidase family U32 C-terminal domain K08303 - - 3.871e-272 842.0
MMS2_k127_3909299_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.126e-236 737.0
MMS2_k127_3909299_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.846e-232 721.0
MMS2_k127_3909299_7 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 9.297e-207 649.0
MMS2_k127_3909299_8 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 554.0
MMS2_k127_3909299_9 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 552.0
MMS2_k127_4059182_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1119.0
MMS2_k127_4059182_1 HI0933-like protein K07007 - - 1.309e-195 617.0
MMS2_k127_4059182_10 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000005436 151.0
MMS2_k127_4059182_2 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 579.0
MMS2_k127_4059182_3 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 530.0
MMS2_k127_4059182_4 Dienelactone hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 376.0
MMS2_k127_4059182_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 345.0
MMS2_k127_4059182_6 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 309.0
MMS2_k127_4059182_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 306.0
MMS2_k127_4059182_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001632 267.0
MMS2_k127_4059182_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000006964 258.0
MMS2_k127_4062606_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1611.0
MMS2_k127_4062606_1 AMP-binding enzyme K01897 - 6.2.1.3 8.706e-209 670.0
MMS2_k127_4062606_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 558.0
MMS2_k127_4062606_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 482.0
MMS2_k127_4062606_4 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 472.0
MMS2_k127_4062606_5 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 397.0
MMS2_k127_4062606_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 385.0
MMS2_k127_4062606_7 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 331.0
MMS2_k127_4062606_8 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006214 251.0
MMS2_k127_4062606_9 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000000000000000000000000448 217.0
MMS2_k127_4099215_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1221.0
MMS2_k127_4099215_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1045.0
MMS2_k127_4099215_10 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 381.0
MMS2_k127_4099215_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 366.0
MMS2_k127_4099215_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 354.0
MMS2_k127_4099215_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 347.0
MMS2_k127_4099215_14 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 339.0
MMS2_k127_4099215_15 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 336.0
MMS2_k127_4099215_16 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 305.0
MMS2_k127_4099215_17 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 283.0
MMS2_k127_4099215_18 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005058 250.0
MMS2_k127_4099215_19 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001046 243.0
MMS2_k127_4099215_2 AAA domain K16898 - 3.6.4.12 2.932e-259 809.0
MMS2_k127_4099215_20 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000000000003137 236.0
MMS2_k127_4099215_21 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000009941 244.0
MMS2_k127_4099215_22 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000001465 233.0
MMS2_k127_4099215_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
MMS2_k127_4099215_24 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 232.0
MMS2_k127_4099215_25 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000001219 216.0
MMS2_k127_4099215_26 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000003883 209.0
MMS2_k127_4099215_27 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000000002225 201.0
MMS2_k127_4099215_28 SpoIIAA-like - - - 0.00000000000000000000000000000000000000000000000000000005591 197.0
MMS2_k127_4099215_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000773 196.0
MMS2_k127_4099215_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.697e-250 775.0
MMS2_k127_4099215_30 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000001206 183.0
MMS2_k127_4099215_31 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000008506 177.0
MMS2_k127_4099215_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000001935 177.0
MMS2_k127_4099215_33 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000000000000001327 175.0
MMS2_k127_4099215_34 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000000000000001071 175.0
MMS2_k127_4099215_35 - - - - 0.0000000000000000000000000000000000000001896 153.0
MMS2_k127_4099215_36 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000003378 143.0
MMS2_k127_4099215_37 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000007115 141.0
MMS2_k127_4099215_38 - - - - 0.00000000000000000000000000000000007939 137.0
MMS2_k127_4099215_39 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000000000000000001732 114.0
MMS2_k127_4099215_4 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 6.927e-215 675.0
MMS2_k127_4099215_40 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000215 115.0
MMS2_k127_4099215_41 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000006743 100.0
MMS2_k127_4099215_42 translation elongation factor activity K02358 - - 0.0000000000000001028 79.0
MMS2_k127_4099215_43 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000000648 78.0
MMS2_k127_4099215_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 552.0
MMS2_k127_4099215_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 503.0
MMS2_k127_4099215_7 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 477.0
MMS2_k127_4099215_8 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 459.0
MMS2_k127_4099215_9 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 406.0
MMS2_k127_4142150_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 428.0
MMS2_k127_4142150_1 ATPase, P-type transporting, HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.000000000000000000000000000000000000000000000003633 176.0
MMS2_k127_4142760_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 6.332e-203 634.0
MMS2_k127_4142760_1 Involved in the TonB-independent uptake of proteins K03641 - - 3.841e-199 627.0
MMS2_k127_4142760_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 295.0
MMS2_k127_4142760_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 276.0
MMS2_k127_4142760_12 OmpA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
MMS2_k127_4142760_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000005067 216.0
MMS2_k127_4142760_14 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000001432 208.0
MMS2_k127_4142760_15 TolA C-terminal K03646 - - 0.0000000000000000000000000000000000000000000000000000000003753 216.0
MMS2_k127_4142760_16 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000002948 191.0
MMS2_k127_4142760_17 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000000000000001942 182.0
MMS2_k127_4142760_18 PFAM aldo keto reductase - - - 0.00000000000000000000001269 100.0
MMS2_k127_4142760_19 - - - - 0.00000003441 62.0
MMS2_k127_4142760_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 429.0
MMS2_k127_4142760_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 416.0
MMS2_k127_4142760_4 beta-lactamase domain protein K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 367.0
MMS2_k127_4142760_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 367.0
MMS2_k127_4142760_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 361.0
MMS2_k127_4142760_7 AAA domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 359.0
MMS2_k127_4142760_8 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 344.0
MMS2_k127_4142760_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 305.0
MMS2_k127_4161469_0 Sucrose synthase K00695 - 2.4.1.13 0.0 1117.0
MMS2_k127_4161469_1 Glycosyl transferase, group 1 K00696 - 2.4.1.14 0.0 1020.0
MMS2_k127_4161469_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 530.0
MMS2_k127_4161469_11 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 517.0
MMS2_k127_4161469_12 cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 514.0
MMS2_k127_4161469_13 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 457.0
MMS2_k127_4161469_14 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 427.0
MMS2_k127_4161469_15 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 411.0
MMS2_k127_4161469_16 PfkB domain protein K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 395.0
MMS2_k127_4161469_17 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 391.0
MMS2_k127_4161469_18 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 385.0
MMS2_k127_4161469_19 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 384.0
MMS2_k127_4161469_2 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 1.518e-295 909.0
MMS2_k127_4161469_20 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 380.0
MMS2_k127_4161469_21 Dinitrogenase reductase K05951 - 2.4.2.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 340.0
MMS2_k127_4161469_22 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 323.0
MMS2_k127_4161469_23 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 318.0
MMS2_k127_4161469_24 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 289.0
MMS2_k127_4161469_25 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002375 276.0
MMS2_k127_4161469_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004252 260.0
MMS2_k127_4161469_27 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000001716 237.0
MMS2_k127_4161469_28 Protein of unknown function, DUF269 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002066 232.0
MMS2_k127_4161469_29 Nitrogen fixation protein NifX K02596 - - 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
MMS2_k127_4161469_3 Belongs to the peptidase S16 family - - - 2.874e-277 876.0
MMS2_k127_4161469_30 Protein of unknown function (DUF2937) - - - 0.00000000000000000000000000000000000000000000000000001329 197.0
MMS2_k127_4161469_31 Belongs to the ArsC family - - - 0.000000000000000000000000000000000000000000000000007681 185.0
MMS2_k127_4161469_32 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000007029 179.0
MMS2_k127_4161469_33 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000001069 174.0
MMS2_k127_4161469_34 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000002563 169.0
MMS2_k127_4161469_35 Ferredoxin III, nif-specific - - - 0.0000000000000000000000000000000000000000005302 159.0
MMS2_k127_4161469_36 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000003837 137.0
MMS2_k127_4161469_37 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000355 116.0
MMS2_k127_4161469_38 NifQ K15790 - - 0.000000000000000000000546 102.0
MMS2_k127_4161469_39 Rop-like - - - 0.0000000000000000001393 89.0
MMS2_k127_4161469_4 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 2.622e-268 832.0
MMS2_k127_4161469_5 Nitrogenase component 1 type Oxidoreductase K02587 - - 4.659e-253 786.0
MMS2_k127_4161469_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 2.765e-239 742.0
MMS2_k127_4161469_7 Belongs to the NifD NifK NifE NifN family K02592 - - 4.171e-200 631.0
MMS2_k127_4161469_8 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 544.0
MMS2_k127_4161469_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 547.0
MMS2_k127_4162183_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.46e-246 777.0
MMS2_k127_4162183_1 Ammonium Transporter Family K03320,K06580 - - 1.102e-241 750.0
MMS2_k127_4162183_10 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 447.0
MMS2_k127_4162183_11 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 417.0
MMS2_k127_4162183_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 332.0
MMS2_k127_4162183_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 322.0
MMS2_k127_4162183_14 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 304.0
MMS2_k127_4162183_15 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 301.0
MMS2_k127_4162183_16 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 299.0
MMS2_k127_4162183_17 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 295.0
MMS2_k127_4162183_18 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000001035 224.0
MMS2_k127_4162183_19 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000129 190.0
MMS2_k127_4162183_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 9.848e-233 728.0
MMS2_k127_4162183_20 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000004012 165.0
MMS2_k127_4162183_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.888e-207 647.0
MMS2_k127_4162183_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 554.0
MMS2_k127_4162183_5 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 550.0
MMS2_k127_4162183_6 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 515.0
MMS2_k127_4162183_7 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 510.0
MMS2_k127_4162183_8 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 478.0
MMS2_k127_4162183_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 475.0
MMS2_k127_4162436_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.041e-257 799.0
MMS2_k127_4162436_1 major facilitator superfamily K03446 - - 5.951e-246 767.0
MMS2_k127_4162436_10 PFAM AMMECR1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
MMS2_k127_4162436_11 Transcription regulator that can specifically activate or repress expression of target genes K06075 - - 0.00000000000000000000000000000000000000000000000000004821 190.0
MMS2_k127_4162436_12 PQ loop repeat K15383 - - 0.0000000000000000000000000000002032 125.0
MMS2_k127_4162436_13 DNA synthesis involved in DNA repair - - - 0.000000000000000003588 85.0
MMS2_k127_4162436_14 - - - - 0.00000000001016 66.0
MMS2_k127_4162436_15 - - - - 0.0000000001673 63.0
MMS2_k127_4162436_2 Pyridoxal-dependent decarboxylase K13745 - 4.1.1.86 1.325e-235 736.0
MMS2_k127_4162436_3 Radical SAM K04069 - 1.97.1.4 7.689e-208 649.0
MMS2_k127_4162436_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 558.0
MMS2_k127_4162436_5 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 509.0
MMS2_k127_4162436_6 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 430.0
MMS2_k127_4162436_7 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 363.0
MMS2_k127_4162436_8 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 304.0
MMS2_k127_4162436_9 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 279.0
MMS2_k127_4169323_0 (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 547.0
MMS2_k127_4169323_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001505 267.0
MMS2_k127_4169323_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000007657 206.0
MMS2_k127_4170259_0 Part of a membrane complex involved in electron transport K03615 - - 1.694e-244 768.0
MMS2_k127_4170259_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 533.0
MMS2_k127_4170259_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 377.0
MMS2_k127_4170259_3 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 355.0
MMS2_k127_4170259_4 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 312.0
MMS2_k127_4170259_5 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004097 275.0
MMS2_k127_4170259_6 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
MMS2_k127_4170259_7 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
MMS2_k127_4170259_8 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000003218 138.0
MMS2_k127_4198678_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 1.588e-264 830.0
MMS2_k127_4198678_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 517.0
MMS2_k127_4198678_2 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 508.0
MMS2_k127_4198678_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 428.0
MMS2_k127_4198678_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 329.0
MMS2_k127_4198678_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008548 267.0
MMS2_k127_4198678_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000001165 124.0
MMS2_k127_4210654_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1069.0
MMS2_k127_4210654_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 602.0
MMS2_k127_4210654_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 271.0
MMS2_k127_4334726_0 Diguanylate cyclase - - - 2.486e-289 904.0
MMS2_k127_4334726_1 Multicopper oxidase - - - 6.423e-241 758.0
MMS2_k127_4334726_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 556.0
MMS2_k127_4334726_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 355.0
MMS2_k127_4334726_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001485 245.0
MMS2_k127_4334726_6 Copper resistance K07233 - - 0.0000003925 58.0
MMS2_k127_4408102_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1560.0
MMS2_k127_4408102_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0 1133.0
MMS2_k127_4408102_10 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 563.0
MMS2_k127_4408102_11 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 530.0
MMS2_k127_4408102_12 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 448.0
MMS2_k127_4408102_13 PFAM cobalamin synthesis protein P47K K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 417.0
MMS2_k127_4408102_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 413.0
MMS2_k127_4408102_15 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 372.0
MMS2_k127_4408102_16 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 355.0
MMS2_k127_4408102_17 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 332.0
MMS2_k127_4408102_18 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 344.0
MMS2_k127_4408102_19 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 332.0
MMS2_k127_4408102_2 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1000.0
MMS2_k127_4408102_20 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 299.0
MMS2_k127_4408102_21 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 276.0
MMS2_k127_4408102_22 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008754 275.0
MMS2_k127_4408102_23 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000862 267.0
MMS2_k127_4408102_24 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000027 263.0
MMS2_k127_4408102_25 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001692 265.0
MMS2_k127_4408102_26 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000004704 224.0
MMS2_k127_4408102_27 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000003357 220.0
MMS2_k127_4408102_28 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.0000000000000000000000000000000000006665 143.0
MMS2_k127_4408102_29 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000406 137.0
MMS2_k127_4408102_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.536e-284 878.0
MMS2_k127_4408102_30 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000000000002822 128.0
MMS2_k127_4408102_31 Protein of unknown function (DUF3106) - - - 0.000000000000000000000001604 110.0
MMS2_k127_4408102_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.422e-249 776.0
MMS2_k127_4408102_5 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 4.914e-219 682.0
MMS2_k127_4408102_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.235e-204 637.0
MMS2_k127_4408102_7 serine threonine protein kinase K12132 - 2.7.11.1 2.182e-203 643.0
MMS2_k127_4408102_8 PFAM AIR synthase related protein domain protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 600.0
MMS2_k127_4408102_9 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 561.0
MMS2_k127_4466983_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.529e-310 966.0
MMS2_k127_4466983_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.434e-252 786.0
MMS2_k127_4466983_10 Protein of unknown function (DUF2892) - - - 0.0000000000000000000002563 98.0
MMS2_k127_4466983_11 Sel1-like repeats. K07126 - - 0.000000000000000000005589 99.0
MMS2_k127_4466983_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 565.0
MMS2_k127_4466983_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 540.0
MMS2_k127_4466983_4 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 401.0
MMS2_k127_4466983_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 328.0
MMS2_k127_4466983_6 Type II secretory pathway, component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000137 265.0
MMS2_k127_4466983_7 Smr domain - - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
MMS2_k127_4466983_8 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000001027 194.0
MMS2_k127_4466983_9 NlpC/P60 family K19303 - - 0.000000000000000000000000000000000000000000000001529 185.0
MMS2_k127_4563567_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1056.0
MMS2_k127_4563567_1 ABC transporter transmembrane region K06147 - - 2.379e-283 880.0
MMS2_k127_4563567_10 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000002123 121.0
MMS2_k127_4563567_2 Amino acid permease - - - 6.781e-227 715.0
MMS2_k127_4563567_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 9.912e-194 610.0
MMS2_k127_4563567_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 436.0
MMS2_k127_4563567_5 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 329.0
MMS2_k127_4563567_6 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
MMS2_k127_4563567_7 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000002418 217.0
MMS2_k127_4563567_8 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.00000000000000000000000000000000000001047 147.0
MMS2_k127_4563567_9 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.00000000000000000000000000000006275 128.0
MMS2_k127_4580880_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1085.0
MMS2_k127_4580880_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 5.907e-320 984.0
MMS2_k127_4580880_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 478.0
MMS2_k127_4580880_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 468.0
MMS2_k127_4580880_12 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 426.0
MMS2_k127_4580880_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 370.0
MMS2_k127_4580880_14 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 368.0
MMS2_k127_4580880_15 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 364.0
MMS2_k127_4580880_16 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 348.0
MMS2_k127_4580880_17 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 321.0
MMS2_k127_4580880_18 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000001723 219.0
MMS2_k127_4580880_19 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000000000000001937 199.0
MMS2_k127_4580880_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.719e-245 761.0
MMS2_k127_4580880_20 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000002234 190.0
MMS2_k127_4580880_21 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002356 183.0
MMS2_k127_4580880_22 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000000002953 135.0
MMS2_k127_4580880_23 Trm112p-like protein K09791 - - 0.00000000000000000000000004648 108.0
MMS2_k127_4580880_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 5.176e-242 751.0
MMS2_k127_4580880_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.715e-239 751.0
MMS2_k127_4580880_5 Belongs to the DegT DnrJ EryC1 family - - - 4.008e-195 621.0
MMS2_k127_4580880_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 600.0
MMS2_k127_4580880_7 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 544.0
MMS2_k127_4580880_8 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 501.0
MMS2_k127_4580880_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 492.0
MMS2_k127_4593044_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.664e-232 725.0
MMS2_k127_4593044_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 599.0
MMS2_k127_4593044_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 302.0
MMS2_k127_4593044_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 264.0
MMS2_k127_4593044_12 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002685 275.0
MMS2_k127_4593044_13 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000002581 267.0
MMS2_k127_4593044_14 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000823 243.0
MMS2_k127_4593044_15 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000003091 218.0
MMS2_k127_4593044_16 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000586 224.0
MMS2_k127_4593044_17 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000005007 185.0
MMS2_k127_4593044_18 PFAM FecR protein K03832 - - 0.0000000000000000000000000000000009151 138.0
MMS2_k127_4593044_19 psiF repeat - - - 0.00000000004885 65.0
MMS2_k127_4593044_2 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 575.0
MMS2_k127_4593044_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 466.0
MMS2_k127_4593044_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 404.0
MMS2_k127_4593044_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 404.0
MMS2_k127_4593044_6 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 373.0
MMS2_k127_4593044_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 368.0
MMS2_k127_4593044_8 Bacterial dnaA protein K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 321.0
MMS2_k127_4593044_9 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 312.0
MMS2_k127_4593627_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1415.0
MMS2_k127_4593627_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1158.0
MMS2_k127_4593627_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.967e-213 665.0
MMS2_k127_4593627_11 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.165e-213 666.0
MMS2_k127_4593627_12 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 7.7e-211 662.0
MMS2_k127_4593627_13 Belongs to the peptidase M16 family K07263 - - 3.866e-202 638.0
MMS2_k127_4593627_14 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 606.0
MMS2_k127_4593627_15 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 599.0
MMS2_k127_4593627_16 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 598.0
MMS2_k127_4593627_17 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 594.0
MMS2_k127_4593627_18 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 586.0
MMS2_k127_4593627_19 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 556.0
MMS2_k127_4593627_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.63e-322 990.0
MMS2_k127_4593627_20 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 542.0
MMS2_k127_4593627_21 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 558.0
MMS2_k127_4593627_22 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 555.0
MMS2_k127_4593627_23 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 530.0
MMS2_k127_4593627_24 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 532.0
MMS2_k127_4593627_25 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 536.0
MMS2_k127_4593627_26 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 531.0
MMS2_k127_4593627_27 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 522.0
MMS2_k127_4593627_28 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 542.0
MMS2_k127_4593627_29 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 515.0
MMS2_k127_4593627_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.562e-318 985.0
MMS2_k127_4593627_30 PFAM Pyruvate kinase barrel K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 508.0
MMS2_k127_4593627_31 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 496.0
MMS2_k127_4593627_32 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 491.0
MMS2_k127_4593627_33 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 482.0
MMS2_k127_4593627_34 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
MMS2_k127_4593627_35 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 434.0
MMS2_k127_4593627_36 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 432.0
MMS2_k127_4593627_37 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 411.0
MMS2_k127_4593627_38 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 398.0
MMS2_k127_4593627_39 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 398.0
MMS2_k127_4593627_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 5.688e-311 961.0
MMS2_k127_4593627_40 Sigma-70 factor, region 1.2 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 400.0
MMS2_k127_4593627_41 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 389.0
MMS2_k127_4593627_42 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 379.0
MMS2_k127_4593627_43 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 375.0
MMS2_k127_4593627_44 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 370.0
MMS2_k127_4593627_45 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 360.0
MMS2_k127_4593627_46 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 351.0
MMS2_k127_4593627_47 Glutathione S-transferase, C-terminal domain K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 348.0
MMS2_k127_4593627_48 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 354.0
MMS2_k127_4593627_49 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 351.0
MMS2_k127_4593627_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.785e-274 855.0
MMS2_k127_4593627_50 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 349.0
MMS2_k127_4593627_51 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 346.0
MMS2_k127_4593627_52 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 336.0
MMS2_k127_4593627_53 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 326.0
MMS2_k127_4593627_54 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 322.0
MMS2_k127_4593627_55 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 318.0
MMS2_k127_4593627_56 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 314.0
MMS2_k127_4593627_57 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 327.0
MMS2_k127_4593627_58 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 293.0
MMS2_k127_4593627_59 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 285.0
MMS2_k127_4593627_6 Polysulphide reductase, NrfD K00185 - - 1.369e-272 842.0
MMS2_k127_4593627_60 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 289.0
MMS2_k127_4593627_61 Cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
MMS2_k127_4593627_62 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005381 279.0
MMS2_k127_4593627_63 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001704 274.0
MMS2_k127_4593627_64 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002923 276.0
MMS2_k127_4593627_65 PFAM porin Gram-negative type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008135 268.0
MMS2_k127_4593627_66 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000006677 256.0
MMS2_k127_4593627_67 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000386 252.0
MMS2_k127_4593627_68 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000598 251.0
MMS2_k127_4593627_69 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000009975 249.0
MMS2_k127_4593627_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.013e-255 799.0
MMS2_k127_4593627_70 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002843 239.0
MMS2_k127_4593627_71 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000005525 236.0
MMS2_k127_4593627_72 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
MMS2_k127_4593627_73 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000004133 227.0
MMS2_k127_4593627_74 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000000001569 224.0
MMS2_k127_4593627_75 HIT domain K02503 - - 0.00000000000000000000000000000000000000000000000000000000000001648 216.0
MMS2_k127_4593627_76 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000002446 224.0
MMS2_k127_4593627_77 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000000000000007718 215.0
MMS2_k127_4593627_78 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000001252 205.0
MMS2_k127_4593627_79 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000000000025 203.0
MMS2_k127_4593627_8 PFAM peptidase M17 leucyl aminopeptidase domain protein K01255 - 3.4.11.1 2.436e-251 781.0
MMS2_k127_4593627_80 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000003132 203.0
MMS2_k127_4593627_81 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000002079 200.0
MMS2_k127_4593627_82 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000001642 195.0
MMS2_k127_4593627_83 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000000000004677 180.0
MMS2_k127_4593627_84 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000007175 182.0
MMS2_k127_4593627_85 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000001291 173.0
MMS2_k127_4593627_86 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000001181 174.0
MMS2_k127_4593627_87 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000003506 162.0
MMS2_k127_4593627_88 SMART RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000000000000002142 163.0
MMS2_k127_4593627_89 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000005674 131.0
MMS2_k127_4593627_9 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 3.601e-226 706.0
MMS2_k127_4593627_90 Methyltransferase domain - - - 0.00000000000000000000000000000007401 133.0
MMS2_k127_4593627_91 transmembrane transport - - - 0.0000000000000000000000000000001334 132.0
MMS2_k127_4593627_92 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000004504 123.0
MMS2_k127_4593627_93 S4 domain K14761 - - 0.00000000000000000000001665 102.0
MMS2_k127_4593627_94 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000003927 96.0
MMS2_k127_4593627_96 maltose operon periplasmic K05775 - - 0.0000000003886 72.0
MMS2_k127_4593627_97 Pfam:DUF1602 - - - 0.000000001856 61.0
MMS2_k127_4593627_98 - - - - 0.0000004231 63.0
MMS2_k127_4684470_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1228.0
MMS2_k127_4684470_1 PFAM ABC transporter related K01990,K09695 - - 1.298e-277 863.0
MMS2_k127_4684470_10 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000004376 168.0
MMS2_k127_4684470_11 Short C-terminal domain K08982 - - 0.0000000000000001807 85.0
MMS2_k127_4684470_2 ABC-2 type transporter K01992 - - 7.022e-196 615.0
MMS2_k127_4684470_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 587.0
MMS2_k127_4684470_4 PFAM secretion protein HlyD family protein K01993,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 398.0
MMS2_k127_4684470_5 Repeat of Unknown Function (DUF347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 381.0
MMS2_k127_4684470_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
MMS2_k127_4684470_7 Copper resistance protein B precursor (CopB) K07233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008013 256.0
MMS2_k127_4684470_8 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000000102 218.0
MMS2_k127_4684470_9 Cytochrome c - - - 0.00000000000000000000000000000000000000001912 159.0
MMS2_k127_4690374_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.071e-317 976.0
MMS2_k127_4690374_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 5.419e-252 796.0
MMS2_k127_4690374_10 Domain of unknown function (DUF202) K00389 - - 0.000000000001044 73.0
MMS2_k127_4690374_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.873e-247 770.0
MMS2_k127_4690374_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 1.971e-230 717.0
MMS2_k127_4690374_4 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 578.0
MMS2_k127_4690374_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 498.0
MMS2_k127_4690374_6 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 363.0
MMS2_k127_4690374_7 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
MMS2_k127_4690374_8 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002318 183.0
MMS2_k127_4690374_9 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000000006493 179.0
MMS2_k127_4697721_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1549.0
MMS2_k127_4697721_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1269.0
MMS2_k127_4697721_10 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 6.611e-217 676.0
MMS2_k127_4697721_11 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.04e-213 666.0
MMS2_k127_4697721_12 PFAM aminotransferase class I and II K14267 - 2.6.1.17 1.449e-210 660.0
MMS2_k127_4697721_13 Nif-specific regulatory protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 596.0
MMS2_k127_4697721_14 PFAM type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 583.0
MMS2_k127_4697721_15 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 577.0
MMS2_k127_4697721_16 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 560.0
MMS2_k127_4697721_17 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 507.0
MMS2_k127_4697721_18 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 484.0
MMS2_k127_4697721_19 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
MMS2_k127_4697721_2 Elongation factor G C-terminus K06207 - - 0.0 1131.0
MMS2_k127_4697721_20 Domain of unknown function (DUF3393) K08306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 469.0
MMS2_k127_4697721_21 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 460.0
MMS2_k127_4697721_22 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 460.0
MMS2_k127_4697721_23 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 458.0
MMS2_k127_4697721_24 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 443.0
MMS2_k127_4697721_25 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 419.0
MMS2_k127_4697721_26 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 392.0
MMS2_k127_4697721_27 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 383.0
MMS2_k127_4697721_28 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 341.0
MMS2_k127_4697721_29 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 338.0
MMS2_k127_4697721_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.05e-297 923.0
MMS2_k127_4697721_30 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 321.0
MMS2_k127_4697721_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 310.0
MMS2_k127_4697721_32 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 310.0
MMS2_k127_4697721_33 ATP-binding protein K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 308.0
MMS2_k127_4697721_35 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 288.0
MMS2_k127_4697721_36 TOBE domain K02019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 286.0
MMS2_k127_4697721_37 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003748 271.0
MMS2_k127_4697721_38 LRV protein FeS4 cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001806 275.0
MMS2_k127_4697721_39 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006803 241.0
MMS2_k127_4697721_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.86e-293 908.0
MMS2_k127_4697721_40 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004362 235.0
MMS2_k127_4697721_41 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000009041 229.0
MMS2_k127_4697721_42 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
MMS2_k127_4697721_43 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000002652 222.0
MMS2_k127_4697721_44 transport system periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000000000000000000002043 227.0
MMS2_k127_4697721_45 Bacterial-like globin - - - 0.000000000000000000000000000000000000000000000000000000000003681 216.0
MMS2_k127_4697721_46 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000001301 199.0
MMS2_k127_4697721_47 - - - - 0.0000000000000000000000000000000000000000000000000000000648 201.0
MMS2_k127_4697721_48 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000008666 187.0
MMS2_k127_4697721_49 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000007344 182.0
MMS2_k127_4697721_5 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 2.388e-277 859.0
MMS2_k127_4697721_50 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000001543 188.0
MMS2_k127_4697721_51 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.0000000000000000000000000000000000000000000000004899 176.0
MMS2_k127_4697721_52 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000000000003474 179.0
MMS2_k127_4697721_53 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000584 181.0
MMS2_k127_4697721_54 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003017 175.0
MMS2_k127_4697721_55 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000006973 177.0
MMS2_k127_4697721_56 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000001001 164.0
MMS2_k127_4697721_57 Ferredoxin - - - 0.0000000000000000000000000000000000000000003564 162.0
MMS2_k127_4697721_58 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000001983 156.0
MMS2_k127_4697721_59 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000000000002955 158.0
MMS2_k127_4697721_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.146e-274 847.0
MMS2_k127_4697721_60 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000008119 152.0
MMS2_k127_4697721_61 NifZ domain K02597 - - 0.000000000000000000000000000000000001543 140.0
MMS2_k127_4697721_62 4Fe-4S binding domain - - - 0.0000000000000000000000000000000005277 134.0
MMS2_k127_4697721_63 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02019 - - 0.000000000000000000000000000000009323 139.0
MMS2_k127_4697721_64 PFAM NifZ family protein K02597 - - 0.00000000000000000000000000000006509 126.0
MMS2_k127_4697721_65 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000004779 124.0
MMS2_k127_4697721_66 May protect the nitrogenase Fe-Mo protein from oxidative damage K02595 - - 0.00000000000000000000000001645 118.0
MMS2_k127_4697721_67 - - - - 0.00000000000000000000000003207 114.0
MMS2_k127_4697721_68 NifT/FixU protein K02593 - - 0.00000000000000000000000005235 112.0
MMS2_k127_4697721_69 - - - - 0.000000000000000000002802 98.0
MMS2_k127_4697721_7 PFAM TonB-dependent receptor plug K02014 - - 5.792e-244 771.0
MMS2_k127_4697721_72 - - - - 0.000000000000000683 81.0
MMS2_k127_4697721_73 - - - - 0.00000000000003071 78.0
MMS2_k127_4697721_74 - - - - 0.00000001919 59.0
MMS2_k127_4697721_75 - - - - 0.0000000203 56.0
MMS2_k127_4697721_77 Alginate export - - - 0.0002368 47.0
MMS2_k127_4697721_8 FAD dependent oxidoreductase K00313 - - 8.482e-226 706.0
MMS2_k127_4697721_9 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 9.434e-224 701.0
MMS2_k127_4791313_0 Acyl-CoA dehydrogenase, N-terminal domain K06445 - - 0.0 1293.0
MMS2_k127_4791313_1 fad dependent oxidoreductase K07137 - - 1.346e-289 899.0
MMS2_k127_4791313_10 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 294.0
MMS2_k127_4791313_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 295.0
MMS2_k127_4791313_12 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 289.0
MMS2_k127_4791313_13 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 275.0
MMS2_k127_4791313_14 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002687 272.0
MMS2_k127_4791313_15 PFAM thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000000000000000000000000000007645 230.0
MMS2_k127_4791313_16 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000006495 220.0
MMS2_k127_4791313_17 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000002575 191.0
MMS2_k127_4791313_18 DsrC like protein K11179 - - 0.0000000000000000000000000000000006089 135.0
MMS2_k127_4791313_2 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 9.942e-286 882.0
MMS2_k127_4791313_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.578e-270 835.0
MMS2_k127_4791313_4 AMP-binding enzyme K01897 - 6.2.1.3 8.533e-255 798.0
MMS2_k127_4791313_5 lysine 2,3-aminomutase K01843 - 5.4.3.2 1.478e-241 752.0
MMS2_k127_4791313_6 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 474.0
MMS2_k127_4791313_7 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 427.0
MMS2_k127_4791313_8 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 423.0
MMS2_k127_4791313_9 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 410.0
MMS2_k127_515383_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 2147.0
MMS2_k127_515383_1 PFAM ABC transporter related - - - 0.0 1000.0
MMS2_k127_515383_10 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
MMS2_k127_515383_11 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 356.0
MMS2_k127_515383_12 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 348.0
MMS2_k127_515383_13 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 285.0
MMS2_k127_515383_14 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000499 265.0
MMS2_k127_515383_15 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
MMS2_k127_515383_16 Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009772 247.0
MMS2_k127_515383_17 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000000003844 221.0
MMS2_k127_515383_18 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000001772 231.0
MMS2_k127_515383_19 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000006492 169.0
MMS2_k127_515383_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.054e-290 899.0
MMS2_k127_515383_20 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000001054 154.0
MMS2_k127_515383_21 Membrane fusogenic activity K09806 - - 0.00000000000000000000002922 100.0
MMS2_k127_515383_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.803e-271 839.0
MMS2_k127_515383_4 Glutamate-cysteine ligase K01919 - 6.3.2.2 6.849e-237 737.0
MMS2_k127_515383_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 6.182e-202 633.0
MMS2_k127_515383_6 Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 589.0
MMS2_k127_515383_7 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 554.0
MMS2_k127_515383_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 497.0
MMS2_k127_515383_9 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 484.0
MMS2_k127_552225_0 AcrB/AcrD/AcrF family - - - 0.0 1479.0
MMS2_k127_552225_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.966e-226 704.0
MMS2_k127_552225_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 347.0
MMS2_k127_552225_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 329.0
MMS2_k127_552225_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009168 254.0
MMS2_k127_557252_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1576.0
MMS2_k127_557252_1 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 621.0
MMS2_k127_557252_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 593.0
MMS2_k127_557252_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 418.0
MMS2_k127_557252_4 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 322.0
MMS2_k127_557252_5 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 320.0
MMS2_k127_557252_6 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 317.0
MMS2_k127_557252_7 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008407 242.0
MMS2_k127_557252_8 LemA family - - - 0.00000000000000000000000000000000000000000000005073 175.0
MMS2_k127_557252_9 - - - - 0.0000003338 63.0
MMS2_k127_568450_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1482.0
MMS2_k127_568450_1 Carbon starvation protein CstA K06200 - - 0.0 1124.0
MMS2_k127_568450_10 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 1.016e-195 624.0
MMS2_k127_568450_11 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 609.0
MMS2_k127_568450_12 4 iron, 4 sulfur cluster binding K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 567.0
MMS2_k127_568450_13 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 542.0
MMS2_k127_568450_14 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 511.0
MMS2_k127_568450_15 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 506.0
MMS2_k127_568450_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 495.0
MMS2_k127_568450_17 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 495.0
MMS2_k127_568450_18 Sulfatase-modifying factor enzyme 1 K20333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 487.0
MMS2_k127_568450_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 467.0
MMS2_k127_568450_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.143e-305 949.0
MMS2_k127_568450_20 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 434.0
MMS2_k127_568450_21 P-loop ATPase protein family K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 434.0
MMS2_k127_568450_22 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 424.0
MMS2_k127_568450_23 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 399.0
MMS2_k127_568450_25 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 318.0
MMS2_k127_568450_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006137 280.0
MMS2_k127_568450_27 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
MMS2_k127_568450_28 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
MMS2_k127_568450_29 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000002165 263.0
MMS2_k127_568450_3 PFAM cytochrome c oxidase subunit I K00404 - 1.9.3.1 2.651e-288 887.0
MMS2_k127_568450_30 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008252 257.0
MMS2_k127_568450_31 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005329 253.0
MMS2_k127_568450_32 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 246.0
MMS2_k127_568450_33 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003392 252.0
MMS2_k127_568450_34 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005003 244.0
MMS2_k127_568450_35 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000009118 216.0
MMS2_k127_568450_36 - - - - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
MMS2_k127_568450_37 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000008102 216.0
MMS2_k127_568450_38 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000257 209.0
MMS2_k127_568450_39 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000001797 198.0
MMS2_k127_568450_4 Spermidine synthase K00797 - 2.5.1.16 5.231e-285 900.0
MMS2_k127_568450_40 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000000000001033 196.0
MMS2_k127_568450_41 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000002163 195.0
MMS2_k127_568450_42 - - - - 0.000000000000000000000000000000000000000000000000001443 184.0
MMS2_k127_568450_43 - - - - 0.000000000000000000000000000000000000000000000005886 176.0
MMS2_k127_568450_44 - - - - 0.00000000000000000000000000000000000000000000001449 176.0
MMS2_k127_568450_45 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000000000001955 172.0
MMS2_k127_568450_46 - - - - 0.000000000000000000000000000000000000000001786 160.0
MMS2_k127_568450_47 Ribosomal protein L31 K02909 - - 0.0000000000000000000000000000000000001608 143.0
MMS2_k127_568450_48 translation initiation factor activity - - - 0.00000000000000000000000000000000002811 143.0
MMS2_k127_568450_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 2.056e-254 794.0
MMS2_k127_568450_50 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000001342 118.0
MMS2_k127_568450_51 - - - - 0.00000000000000000000000001703 112.0
MMS2_k127_568450_52 - - - - 0.00000000000000000000000363 106.0
MMS2_k127_568450_53 - - - - 0.000000000000000000008789 98.0
MMS2_k127_568450_54 Selenoprotein, putative - - - 0.000000000000001984 80.0
MMS2_k127_568450_55 - K06950 - - 0.00000000000004352 74.0
MMS2_k127_568450_56 NusG domain II - - - 0.00000000000006872 76.0
MMS2_k127_568450_57 - - - - 0.000000001932 63.0
MMS2_k127_568450_58 - - - - 0.000000003243 63.0
MMS2_k127_568450_59 Glycosyl transferase family 41 - - - 0.000051 49.0
MMS2_k127_568450_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 3.044e-219 688.0
MMS2_k127_568450_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 2.853e-218 680.0
MMS2_k127_568450_8 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 6.708e-206 645.0
MMS2_k127_568450_9 Peptidase family M48 - - - 2.784e-202 640.0
MMS2_k127_575821_0 ABC transporter C-terminal domain K15738 - - 0.0 1049.0
MMS2_k127_575821_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 2.626e-216 677.0
MMS2_k127_575821_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000002046 271.0
MMS2_k127_575821_11 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001322 252.0
MMS2_k127_575821_12 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000297 230.0
MMS2_k127_575821_13 PFAM HopJ type III effector protein - - - 0.00000000000000000000000000000000000000000000000000004201 190.0
MMS2_k127_575821_14 family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000004626 190.0
MMS2_k127_575821_15 Domain of unknown function (DUF4824) - - - 0.000000000000000000000000000000000000000000000001298 188.0
MMS2_k127_575821_16 - - - - 0.000000000000000000000000000000000000000000000004377 180.0
MMS2_k127_575821_17 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000000000325 151.0
MMS2_k127_575821_18 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000000007801 144.0
MMS2_k127_575821_19 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000005689 135.0
MMS2_k127_575821_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 537.0
MMS2_k127_575821_20 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000001195 132.0
MMS2_k127_575821_21 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000005693 128.0
MMS2_k127_575821_22 VanZ like family - - - 0.000000000000000000000000003389 115.0
MMS2_k127_575821_23 - - - - 0.000000000000000000002502 98.0
MMS2_k127_575821_24 - - - - 0.00000000000000000004235 94.0
MMS2_k127_575821_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 506.0
MMS2_k127_575821_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 498.0
MMS2_k127_575821_5 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 484.0
MMS2_k127_575821_6 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 458.0
MMS2_k127_575821_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 375.0
MMS2_k127_575821_8 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 368.0
MMS2_k127_575821_9 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
MMS2_k127_596238_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2159.0
MMS2_k127_596238_1 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1436.0
MMS2_k127_596238_10 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 1.028e-296 932.0
MMS2_k127_596238_101 - - - - 0.000000000000162 75.0
MMS2_k127_596238_102 Protein of unknown function (DUF2934) - - - 0.0000000000004072 74.0
MMS2_k127_596238_103 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0000000001333 68.0
MMS2_k127_596238_104 - - - - 0.0000009893 57.0
MMS2_k127_596238_11 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.043e-276 862.0
MMS2_k127_596238_12 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 1.244e-275 862.0
MMS2_k127_596238_13 Large family of predicted nucleotide-binding domains K07175 - - 4.66e-253 787.0
MMS2_k127_596238_14 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.771e-251 780.0
MMS2_k127_596238_15 Belongs to the GPI family K01810 - 5.3.1.9 1.563e-246 771.0
MMS2_k127_596238_16 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 1.351e-238 741.0
MMS2_k127_596238_17 Belongs to the glycosyl hydrolase 57 family - - - 2.382e-237 749.0
MMS2_k127_596238_18 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.011e-235 733.0
MMS2_k127_596238_19 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 7.623e-231 718.0
MMS2_k127_596238_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1395.0
MMS2_k127_596238_20 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.083e-230 716.0
MMS2_k127_596238_21 SurA N-terminal domain K03770 - 5.2.1.8 1.381e-227 721.0
MMS2_k127_596238_22 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.96e-222 694.0
MMS2_k127_596238_23 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.76 1.388e-220 690.0
MMS2_k127_596238_24 COG0025 NhaP-type Na H and K H antiporters K03316 - - 1.06e-210 681.0
MMS2_k127_596238_25 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 2.208e-205 647.0
MMS2_k127_596238_26 Diguanylate cyclase - - - 4.789e-197 634.0
MMS2_k127_596238_27 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 593.0
MMS2_k127_596238_28 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 589.0
MMS2_k127_596238_29 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 588.0
MMS2_k127_596238_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1191.0
MMS2_k127_596238_30 PFAM Peptidase family M20 M25 M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 575.0
MMS2_k127_596238_31 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 558.0
MMS2_k127_596238_32 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 570.0
MMS2_k127_596238_33 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 551.0
MMS2_k127_596238_34 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 557.0
MMS2_k127_596238_35 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 536.0
MMS2_k127_596238_36 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 503.0
MMS2_k127_596238_37 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 491.0
MMS2_k127_596238_38 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 497.0
MMS2_k127_596238_39 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 477.0
MMS2_k127_596238_4 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1185.0
MMS2_k127_596238_40 LysM domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 479.0
MMS2_k127_596238_41 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 454.0
MMS2_k127_596238_42 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 456.0
MMS2_k127_596238_43 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 449.0
MMS2_k127_596238_44 PFAM GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 443.0
MMS2_k127_596238_45 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 434.0
MMS2_k127_596238_46 mechano-sensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 435.0
MMS2_k127_596238_47 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 424.0
MMS2_k127_596238_48 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 395.0
MMS2_k127_596238_49 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 370.0
MMS2_k127_596238_5 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1113.0
MMS2_k127_596238_50 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 369.0
MMS2_k127_596238_51 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 353.0
MMS2_k127_596238_52 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
MMS2_k127_596238_53 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 329.0
MMS2_k127_596238_54 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 323.0
MMS2_k127_596238_55 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 299.0
MMS2_k127_596238_56 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 309.0
MMS2_k127_596238_57 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 297.0
MMS2_k127_596238_58 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 290.0
MMS2_k127_596238_59 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 291.0
MMS2_k127_596238_6 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1109.0
MMS2_k127_596238_60 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 289.0
MMS2_k127_596238_61 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001782 283.0
MMS2_k127_596238_62 Intracellular septation protein A K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001435 274.0
MMS2_k127_596238_63 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004741 261.0
MMS2_k127_596238_64 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002251 257.0
MMS2_k127_596238_65 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
MMS2_k127_596238_66 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000009173 257.0
MMS2_k127_596238_67 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001103 254.0
MMS2_k127_596238_68 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 256.0
MMS2_k127_596238_69 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002214 249.0
MMS2_k127_596238_7 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1057.0
MMS2_k127_596238_70 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006875 241.0
MMS2_k127_596238_71 Ectoine synthase K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000000000000005079 226.0
MMS2_k127_596238_72 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001978 230.0
MMS2_k127_596238_73 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000003949 224.0
MMS2_k127_596238_74 - - - - 0.000000000000000000000000000000000000000000000000000000000328 206.0
MMS2_k127_596238_75 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000239 203.0
MMS2_k127_596238_76 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06718 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 0.00000000000000000000000000000000000000000000000000000002214 202.0
MMS2_k127_596238_77 Cytochrome C biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000002661 199.0
MMS2_k127_596238_78 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.000000000000000000000000000000000000000000003168 172.0
MMS2_k127_596238_79 - - - - 0.00000000000000000000000000000000000000000000544 174.0
MMS2_k127_596238_8 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1052.0
MMS2_k127_596238_80 gag-polyprotein putative aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000001563 163.0
MMS2_k127_596238_81 YCII-related domain K09780 - - 0.000000000000000000000000000000000000000007039 157.0
MMS2_k127_596238_82 bacterial (prokaryotic) histone like domain - - - 0.00000000000000000000000000000000000000003252 154.0
MMS2_k127_596238_83 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000001977 147.0
MMS2_k127_596238_84 SpoIIAA-like - - - 0.0000000000000000000000000000000000001971 144.0
MMS2_k127_596238_85 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000001412 147.0
MMS2_k127_596238_86 Cold shock protein domain K03704 - - 0.000000000000000000000000000000004074 128.0
MMS2_k127_596238_87 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000008519 126.0
MMS2_k127_596238_88 Cytochrome c, class I K08738 - - 0.0000000000000000000000000000004136 130.0
MMS2_k127_596238_89 - - - - 0.0000000000000000000000000000008343 124.0
MMS2_k127_596238_9 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.874e-300 934.0
MMS2_k127_596238_90 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000004623 123.0
MMS2_k127_596238_91 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000002521 121.0
MMS2_k127_596238_92 BolA-like protein K05527 - - 0.0000000000000000000000000001689 122.0
MMS2_k127_596238_93 FeoA K04758 - - 0.0000000000000000000000000858 108.0
MMS2_k127_596238_94 - - - - 0.000000000000000000000001426 108.0
MMS2_k127_596238_95 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000009906 93.0
MMS2_k127_596238_96 Tfp pilus assembly protein K02655 - - 0.0000000000000000001272 94.0
MMS2_k127_596238_97 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000008292 85.0
MMS2_k127_596238_98 FecR protein - - - 0.00000000000000004665 93.0
MMS2_k127_596238_99 - - - - 0.000000000000005151 75.0
MMS2_k127_705304_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1043.0
MMS2_k127_705304_1 NADH ubiquinone plastoquinone (Complex I) - - - 1.014e-313 972.0
MMS2_k127_705304_10 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000000368 102.0
MMS2_k127_705304_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 9.795e-270 835.0
MMS2_k127_705304_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 4.348e-260 809.0
MMS2_k127_705304_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 1.387e-207 649.0
MMS2_k127_705304_5 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 495.0
MMS2_k127_705304_6 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 370.0
MMS2_k127_705304_7 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 348.0
MMS2_k127_705304_8 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001137 280.0
MMS2_k127_705304_9 diguanylate cyclase K07216 - - 0.000000000000000000000000000000000000000000000000000000000000000000001571 259.0
MMS2_k127_797118_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1376.0
MMS2_k127_797118_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 3.655e-256 795.0
MMS2_k127_797118_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 353.0
MMS2_k127_797118_11 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 349.0
MMS2_k127_797118_12 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 272.0
MMS2_k127_797118_13 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000597 237.0
MMS2_k127_797118_14 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000003288 171.0
MMS2_k127_797118_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.711e-219 685.0
MMS2_k127_797118_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 3.874e-195 613.0
MMS2_k127_797118_4 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 528.0
MMS2_k127_797118_5 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 515.0
MMS2_k127_797118_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 482.0
MMS2_k127_797118_7 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 449.0
MMS2_k127_797118_8 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 392.0
MMS2_k127_797118_9 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 367.0
MMS2_k127_910495_0 Hsp70 protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1104.0
MMS2_k127_910495_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 7.48e-208 651.0
MMS2_k127_910495_2 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 428.0
MMS2_k127_910495_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 402.0
MMS2_k127_910495_4 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 288.0
MMS2_k127_910495_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001694 266.0
MMS2_k127_910495_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000001252 238.0
MMS2_k127_910495_7 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
MMS2_k127_910495_8 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000001728 165.0
MMS2_k127_96802_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1138.0
MMS2_k127_96802_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 2.842e-269 832.0
MMS2_k127_96802_10 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 7.491e-198 627.0
MMS2_k127_96802_11 Involved in the biosynthesis of porphyrin-containing compound - - - 1.463e-197 623.0
MMS2_k127_96802_12 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 587.0
MMS2_k127_96802_13 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 566.0
MMS2_k127_96802_14 endonuclease III K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 523.0
MMS2_k127_96802_15 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 462.0
MMS2_k127_96802_16 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 458.0
MMS2_k127_96802_17 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 451.0
MMS2_k127_96802_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 436.0
MMS2_k127_96802_19 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 412.0
MMS2_k127_96802_2 AsmA family K07289 - - 1.807e-250 792.0
MMS2_k127_96802_20 histidine kinase HAMP region domain protein K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 424.0
MMS2_k127_96802_21 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
MMS2_k127_96802_22 S4 RNA-binding domain K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 391.0
MMS2_k127_96802_23 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 372.0
MMS2_k127_96802_24 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 371.0
MMS2_k127_96802_25 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 360.0
MMS2_k127_96802_26 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 350.0
MMS2_k127_96802_27 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 346.0
MMS2_k127_96802_28 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 338.0
MMS2_k127_96802_29 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 339.0
MMS2_k127_96802_3 MgtE intracellular N domain K06213 - - 3.13e-249 775.0
MMS2_k127_96802_30 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 321.0
MMS2_k127_96802_31 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 296.0
MMS2_k127_96802_32 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003263 293.0
MMS2_k127_96802_33 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000158 261.0
MMS2_k127_96802_34 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004593 243.0
MMS2_k127_96802_35 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000004684 195.0
MMS2_k127_96802_36 PFAM 20S proteasome, A and B subunits - - - 0.0000000000000000000000000000000000000000000000000006801 189.0
MMS2_k127_96802_37 Frataxin-like domain K06202 - - 0.00000000000000000000000000000000002008 150.0
MMS2_k127_96802_38 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000698 127.0
MMS2_k127_96802_39 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000000001097 121.0
MMS2_k127_96802_4 Putative diguanylate phosphodiesterase - - - 1.308e-241 769.0
MMS2_k127_96802_40 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000000000004372 119.0
MMS2_k127_96802_41 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000002799 109.0
MMS2_k127_96802_42 ThiS family K03154 - - 0.00000000000000000000007569 98.0
MMS2_k127_96802_44 YqjK-like protein - - - 0.0000000000000523 77.0
MMS2_k127_96802_45 Protein of unknown function (DUF2846) - - - 0.00000003851 60.0
MMS2_k127_96802_46 PFAM Prophage CP4-57 regulatory K07733 - - 0.0000001131 57.0
MMS2_k127_96802_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.204e-238 741.0
MMS2_k127_96802_6 Nitronate monooxygenase K00459 - 1.13.12.16 1.102e-229 717.0
MMS2_k127_96802_7 glycyl-tRNA synthetase beta K01879 - 6.1.1.14 1.636e-225 718.0
MMS2_k127_96802_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.706e-205 647.0
MMS2_k127_96802_9 Anthranilate synthase component I domain protein K01665,K13950 - 2.6.1.85 1.76e-200 633.0