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Overview

ID MAG03124
Name PYH1_bin.1
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus
Species
Assembly information
Completeness (%) 82.73
Contamination (%) 0.76
GC content (%) 59.0
N50 (bp) 7,399
Genome size (bp) 1,918,712

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1925

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1014318_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 565.0
PYH1_k127_1014318_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
PYH1_k127_1014318_2 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000002522 203.0
PYH1_k127_1014318_3 Membrane - - - 0.00000000346 70.0
PYH1_k127_1014318_4 Tetratricopeptide repeat - - - 0.00000006898 63.0
PYH1_k127_1014318_5 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.00000007205 63.0
PYH1_k127_1092245_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000002391 241.0
PYH1_k127_1092245_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000003447 226.0
PYH1_k127_1092245_2 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000001477 230.0
PYH1_k127_1092245_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000006469 79.0
PYH1_k127_1092245_4 Prokaryotic homologs of the JAB domain - - - 0.00006275 53.0
PYH1_k127_1132785_0 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000000000000003833 185.0
PYH1_k127_1132785_1 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000002763 160.0
PYH1_k127_1132785_2 SdpI/YhfL protein family - - - 0.000000002297 63.0
PYH1_k127_1137893_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 310.0
PYH1_k127_1137893_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001032 227.0
PYH1_k127_1137893_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000008905 216.0
PYH1_k127_1137893_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000001475 154.0
PYH1_k127_1137893_4 HlyD family secretion protein - - - 0.000000000000000000001004 108.0
PYH1_k127_1176574_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.666e-198 634.0
PYH1_k127_1176574_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000001548 139.0
PYH1_k127_1176574_2 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000001696 88.0
PYH1_k127_1176574_3 iron hydrogenase, small subunit K00336 - 1.6.5.3 0.000000000004215 73.0
PYH1_k127_1197393_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 2.012e-199 634.0
PYH1_k127_1197393_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 520.0
PYH1_k127_1197393_2 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 267.0
PYH1_k127_1197393_3 PFAM GGDEF domain containing protein - - - 0.00000000008326 66.0
PYH1_k127_1217513_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
PYH1_k127_1217513_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
PYH1_k127_1217513_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 283.0
PYH1_k127_1217513_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000456 248.0
PYH1_k127_1217513_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000006184 235.0
PYH1_k127_1217513_5 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000001129 158.0
PYH1_k127_1257982_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 510.0
PYH1_k127_1257982_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 365.0
PYH1_k127_1257982_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000003822 154.0
PYH1_k127_1257982_3 CO dehydrogenase K07321 - - 0.00000000000000000000000003667 108.0
PYH1_k127_127488_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 351.0
PYH1_k127_127488_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 317.0
PYH1_k127_127488_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 306.0
PYH1_k127_127488_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 301.0
PYH1_k127_127488_4 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000009338 171.0
PYH1_k127_127488_5 NosL - - - 0.00000000000000000000000000000000632 141.0
PYH1_k127_127488_6 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000008182 104.0
PYH1_k127_127488_7 - - - - 0.00000000000000001612 86.0
PYH1_k127_1330922_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.773e-267 835.0
PYH1_k127_1330922_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.945e-215 676.0
PYH1_k127_1330922_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 471.0
PYH1_k127_1330922_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 475.0
PYH1_k127_1330922_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 448.0
PYH1_k127_1330922_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 413.0
PYH1_k127_1330922_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 322.0
PYH1_k127_1330922_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 313.0
PYH1_k127_1330922_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000005267 229.0
PYH1_k127_1330922_9 PFAM Amino acid-binding ACT - - - 0.000000000000000000000000000000000000000000000000000000000199 205.0
PYH1_k127_1428079_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006905 274.0
PYH1_k127_1428079_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000004844 135.0
PYH1_k127_1428079_2 May regulate the transcription of the frlABCDR operon, involved in the utilization of fructoselysine and psicoselysine K10711 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000009204 116.0
PYH1_k127_1428079_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000653 63.0
PYH1_k127_1435234_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001056 244.0
PYH1_k127_1435234_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000006696 184.0
PYH1_k127_1435234_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000001669 147.0
PYH1_k127_1435234_3 SMART ATP-binding region ATPase domain protein K03406,K07710 - 2.7.13.3 0.000000000001182 81.0
PYH1_k127_1448648_0 Belongs to the GPI family K01810 - 5.3.1.9 1.678e-259 806.0
PYH1_k127_1448648_1 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
PYH1_k127_1448648_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000004899 190.0
PYH1_k127_1448648_3 - - - - 0.000000000000000000000000000000000000000003133 177.0
PYH1_k127_1448648_4 histidine kinase A domain protein domain protein - - - 0.000000000000007792 87.0
PYH1_k127_1453450_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 581.0
PYH1_k127_1453450_1 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 304.0
PYH1_k127_1453450_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000666 267.0
PYH1_k127_1453450_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000002441 219.0
PYH1_k127_1453450_4 Peptidase M15A - - - 0.0000000000000000000000000003706 121.0
PYH1_k127_1453450_6 HD domain K07023 - - 0.0000001426 52.0
PYH1_k127_1453450_7 SEC-C Motif Domain Protein - - - 0.00001415 57.0
PYH1_k127_1473614_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 8.822e-239 750.0
PYH1_k127_1473614_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 443.0
PYH1_k127_1473614_2 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 385.0
PYH1_k127_1473614_3 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001316 280.0
PYH1_k127_1473614_4 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000001495 152.0
PYH1_k127_1473614_6 Rubrerythrin - - - 0.000000000000002292 82.0
PYH1_k127_1473614_7 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000005294 68.0
PYH1_k127_1475844_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 337.0
PYH1_k127_1475844_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 296.0
PYH1_k127_1475844_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000402 203.0
PYH1_k127_1475844_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000001172 157.0
PYH1_k127_1475844_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000001507 151.0
PYH1_k127_1475844_5 - - - - 0.00000000000000000000008889 100.0
PYH1_k127_1475844_6 energy transducer activity K03646,K03832 - - 0.00000000000001072 83.0
PYH1_k127_148380_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002224 282.0
PYH1_k127_148380_1 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000002925 128.0
PYH1_k127_148380_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000004708 109.0
PYH1_k127_1485585_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 304.0
PYH1_k127_1485585_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009714 263.0
PYH1_k127_1485585_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000796 212.0
PYH1_k127_1485585_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000002019 190.0
PYH1_k127_1485585_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000001526 141.0
PYH1_k127_1485585_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000001188 88.0
PYH1_k127_1485585_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000003539 69.0
PYH1_k127_1555865_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 342.0
PYH1_k127_1555865_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 317.0
PYH1_k127_1555865_2 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006851 280.0
PYH1_k127_1555865_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000002402 213.0
PYH1_k127_1555865_4 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000006715 117.0
PYH1_k127_1574628_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 521.0
PYH1_k127_1574628_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 460.0
PYH1_k127_1574628_2 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 267.0
PYH1_k127_1574628_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000002802 232.0
PYH1_k127_1574628_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000003029 169.0
PYH1_k127_162648_0 Domain of unknown function (DUF3413) K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 422.0
PYH1_k127_162648_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 345.0
PYH1_k127_162648_2 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000007604 230.0
PYH1_k127_162648_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000006734 207.0
PYH1_k127_162648_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000001041 200.0
PYH1_k127_162648_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000002163 192.0
PYH1_k127_162648_6 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000133 170.0
PYH1_k127_162648_7 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000000000000000000000000158 154.0
PYH1_k127_162648_8 dephospho-CoA kinase activity - - - 0.000000000000000000000001146 109.0
PYH1_k127_1639599_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 447.0
PYH1_k127_1639599_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 370.0
PYH1_k127_1639599_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 332.0
PYH1_k127_1639599_3 Type IV pilus assembly - - - 0.0004912 51.0
PYH1_k127_1683522_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 445.0
PYH1_k127_1683522_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
PYH1_k127_1683522_2 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000001464 153.0
PYH1_k127_1683522_3 protein N-acetylglucosaminyltransferase activity - - - 0.000001245 60.0
PYH1_k127_1684540_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 587.0
PYH1_k127_1684540_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 434.0
PYH1_k127_1684540_2 4 iron, 4 sulfur cluster binding K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000874 254.0
PYH1_k127_1684540_3 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001619 253.0
PYH1_k127_1684540_4 4Fe-4S binding domain - - - 0.000000000000000000009509 93.0
PYH1_k127_1684540_5 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000279 61.0
PYH1_k127_1684540_6 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000005493 53.0
PYH1_k127_1684540_7 DsrE/DsrF-like family - - - 0.00003119 51.0
PYH1_k127_169338_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.471e-208 654.0
PYH1_k127_169338_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 385.0
PYH1_k127_169338_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000001776 233.0
PYH1_k127_169338_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
PYH1_k127_169338_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000434 198.0
PYH1_k127_169338_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000005236 198.0
PYH1_k127_169338_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001771 193.0
PYH1_k127_169338_15 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000006021 184.0
PYH1_k127_169338_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001524 176.0
PYH1_k127_169338_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000016 168.0
PYH1_k127_169338_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000003659 156.0
PYH1_k127_169338_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000004859 161.0
PYH1_k127_169338_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 345.0
PYH1_k127_169338_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000003885 149.0
PYH1_k127_169338_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000006635 134.0
PYH1_k127_169338_22 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000007967 136.0
PYH1_k127_169338_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000002268 132.0
PYH1_k127_169338_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000001112 110.0
PYH1_k127_169338_25 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000004033 103.0
PYH1_k127_169338_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003241 102.0
PYH1_k127_169338_27 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000001149 73.0
PYH1_k127_169338_28 Ribosomal protein L36 K02919 - - 0.0000000000001013 71.0
PYH1_k127_169338_29 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000006774 73.0
PYH1_k127_169338_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 335.0
PYH1_k127_169338_30 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001096 68.0
PYH1_k127_169338_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
PYH1_k127_169338_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 290.0
PYH1_k127_169338_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 284.0
PYH1_k127_169338_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002821 282.0
PYH1_k127_169338_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001331 234.0
PYH1_k127_169338_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001381 230.0
PYH1_k127_1698539_0 FtsX-like permease family K02004 - - 2.694e-301 945.0
PYH1_k127_1698539_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 406.0
PYH1_k127_1698539_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 357.0
PYH1_k127_1698539_3 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000791 249.0
PYH1_k127_1698539_4 - - - - 0.0000000000000000000000000000000000000000896 162.0
PYH1_k127_1698539_5 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000001235 154.0
PYH1_k127_1703111_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 564.0
PYH1_k127_1703111_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 447.0
PYH1_k127_1703111_10 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000002137 171.0
PYH1_k127_1703111_11 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000375 157.0
PYH1_k127_1703111_12 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000004502 153.0
PYH1_k127_1703111_13 YGGT family K02221 - - 0.0000000000000000000000000000000001519 137.0
PYH1_k127_1703111_14 cheY-homologous receiver domain - - - 0.0000000000000000000000000001133 121.0
PYH1_k127_1703111_15 Conserved hypothetical protein 698 - - - 0.000000000000000000000000004259 122.0
PYH1_k127_1703111_16 periplasmic ligand-binding sensor domain - - - 0.0000000000000000003501 104.0
PYH1_k127_1703111_17 Diguanylate cyclase - - - 0.0000001353 66.0
PYH1_k127_1703111_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 446.0
PYH1_k127_1703111_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002091 273.0
PYH1_k127_1703111_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005625 250.0
PYH1_k127_1703111_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000002592 227.0
PYH1_k127_1703111_6 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000006406 213.0
PYH1_k127_1703111_7 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000002294 206.0
PYH1_k127_1703111_8 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000001974 199.0
PYH1_k127_1703111_9 HD domain - - - 0.00000000000000000000000000000000000000000000000000000006193 210.0
PYH1_k127_1738072_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 2.912e-249 790.0
PYH1_k127_1738072_1 ABC transporter K06158 - - 1.324e-213 680.0
PYH1_k127_1738072_10 - - - - 0.000000000000000000000000000000000005233 141.0
PYH1_k127_1738072_11 Cation efflux family - - - 0.000000000000000000000000000001186 124.0
PYH1_k127_1738072_12 HAMP domain - - - 0.000000000000000000000000000003572 136.0
PYH1_k127_1738072_13 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000553 110.0
PYH1_k127_1738072_15 DsrE/DsrF-like family - - - 0.0007658 47.0
PYH1_k127_1738072_2 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 531.0
PYH1_k127_1738072_3 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
PYH1_k127_1738072_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 304.0
PYH1_k127_1738072_5 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000001953 169.0
PYH1_k127_1738072_6 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000004994 159.0
PYH1_k127_1738072_7 Histidine kinase - - - 0.00000000000000000000000000000000000000007162 169.0
PYH1_k127_1738072_8 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000001214 153.0
PYH1_k127_1738072_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000001768 148.0
PYH1_k127_1788864_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.153e-234 733.0
PYH1_k127_1788864_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 559.0
PYH1_k127_1788864_2 proteolysis K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000231 240.0
PYH1_k127_1788864_3 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000005166 170.0
PYH1_k127_1788864_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000006871 135.0
PYH1_k127_1788864_5 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000001839 96.0
PYH1_k127_1851835_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 299.0
PYH1_k127_1851835_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000001314 235.0
PYH1_k127_1851835_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000001079 179.0
PYH1_k127_1851835_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000002867 157.0
PYH1_k127_1851835_4 Sulphur transport K07112 - - 0.00000000000000000000000000000000005338 139.0
PYH1_k127_1851835_5 Protein of unknown function (DUF3617) - - - 0.000000000000000000003563 100.0
PYH1_k127_185357_0 PFAM PhoH-like protein K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 437.0
PYH1_k127_185357_1 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 287.0
PYH1_k127_1880403_0 Belongs to the CarB family K01955 - 6.3.5.5 1.343e-293 921.0
PYH1_k127_1880403_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000002052 151.0
PYH1_k127_1891381_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 461.0
PYH1_k127_1891381_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 446.0
PYH1_k127_1891381_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 358.0
PYH1_k127_1891381_3 Telomere recombination K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 326.0
PYH1_k127_1891381_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 308.0
PYH1_k127_1891381_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000003596 140.0
PYH1_k127_1891381_6 - - - - 0.00000000000000000003978 98.0
PYH1_k127_1891381_7 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.0000000000009265 79.0
PYH1_k127_1902099_0 Tripartite tricarboxylate transporter TctA family K07793 - - 3.303e-239 753.0
PYH1_k127_1902099_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.421e-219 686.0
PYH1_k127_1902099_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 487.0
PYH1_k127_1902099_3 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 321.0
PYH1_k127_1902099_4 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000001437 170.0
PYH1_k127_1902099_5 S1 domain K00243 - - 0.000000000000000000000000000000000000000001451 171.0
PYH1_k127_1902099_6 - - - - 0.0000000000000000000000000000000938 128.0
PYH1_k127_1902099_7 - - - - 0.000000000008341 68.0
PYH1_k127_1923481_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 442.0
PYH1_k127_1923481_1 protein secretion K09800 - - 0.00000005565 62.0
PYH1_k127_1923481_2 Transcriptional regulator, GntR family K03710 - - 0.0001907 45.0
PYH1_k127_1949753_0 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 364.0
PYH1_k127_1949753_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000006569 193.0
PYH1_k127_1949753_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0005693 43.0
PYH1_k127_196380_0 4Fe-4S binding domain - - - 3.182e-210 664.0
PYH1_k127_196380_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 456.0
PYH1_k127_196380_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 397.0
PYH1_k127_196380_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004592 282.0
PYH1_k127_196380_4 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
PYH1_k127_196380_5 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000001015 204.0
PYH1_k127_196380_6 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000001062 160.0
PYH1_k127_196380_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001484 159.0
PYH1_k127_196380_8 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000001782 149.0
PYH1_k127_196380_9 Universal stress protein family - - - 0.00000000000000000004092 101.0
PYH1_k127_2004092_0 DEAD DEAH box helicase K06877 - - 7.056e-220 706.0
PYH1_k127_2004092_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002168 276.0
PYH1_k127_2004092_2 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.000000000000000000000000000000004013 135.0
PYH1_k127_2004092_3 protein-disulfide reductase activity - - - 0.0000000000000000000000003852 111.0
PYH1_k127_2004092_4 response to copper ion - - - 0.0000000000000000001109 104.0
PYH1_k127_2004092_5 Copper resistance protein D K07245 - - 0.00000000000001824 87.0
PYH1_k127_2004303_0 catalase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1229.0
PYH1_k127_2004303_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 4.198e-231 731.0
PYH1_k127_2004303_2 Flavodoxin-like fold K03923,K11748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001089 273.0
PYH1_k127_2004303_3 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
PYH1_k127_2004303_4 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000008473 143.0
PYH1_k127_2004303_5 radical SAM K06871 - - 0.000000000000000000000000000000000005672 142.0
PYH1_k127_2004303_6 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000832 98.0
PYH1_k127_2004303_8 - - - - 0.0002045 45.0
PYH1_k127_2006361_0 ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 394.0
PYH1_k127_2006361_1 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 310.0
PYH1_k127_2006361_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008136 265.0
PYH1_k127_2006361_3 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000001435 208.0
PYH1_k127_2006361_4 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000004004 169.0
PYH1_k127_2006361_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000003142 79.0
PYH1_k127_2006361_7 GAF domain - - - 0.00000001484 57.0
PYH1_k127_2011723_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 9.832e-274 865.0
PYH1_k127_2011723_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002717 291.0
PYH1_k127_2011723_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003655 272.0
PYH1_k127_2011723_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.0000000000000000000000000001088 119.0
PYH1_k127_2011723_4 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000002558 96.0
PYH1_k127_2035801_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 464.0
PYH1_k127_2035801_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 439.0
PYH1_k127_2035801_2 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 372.0
PYH1_k127_2035801_3 Domain of unknown function (DUF4129) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 362.0
PYH1_k127_2035801_4 histone acetyltransferase binding - - - 0.0000000000000000000000000000000000000000000000000000000001061 220.0
PYH1_k127_2035801_5 - - - - 0.000000000000000000001971 97.0
PYH1_k127_2035801_6 - - - - 0.00004194 54.0
PYH1_k127_2068598_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 478.0
PYH1_k127_2068598_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 397.0
PYH1_k127_2068598_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 318.0
PYH1_k127_2068598_3 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002698 280.0
PYH1_k127_2068598_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000000000000000000000007722 120.0
PYH1_k127_2068598_5 Protein of unknown function (DUF2905) - - - 0.00000000000000000007956 90.0
PYH1_k127_2080235_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 602.0
PYH1_k127_2080235_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 591.0
PYH1_k127_2080235_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 516.0
PYH1_k127_2080235_3 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 476.0
PYH1_k127_2080235_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
PYH1_k127_2080235_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 338.0
PYH1_k127_2121926_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 469.0
PYH1_k127_2121926_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 443.0
PYH1_k127_2121926_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 304.0
PYH1_k127_215414_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.758e-239 750.0
PYH1_k127_215414_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 600.0
PYH1_k127_215414_2 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 602.0
PYH1_k127_215414_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 489.0
PYH1_k127_215414_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 330.0
PYH1_k127_215414_5 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007668 266.0
PYH1_k127_215414_6 ThiS family K03636 - - 0.000000000000000000000000000000001644 132.0
PYH1_k127_215414_7 NIL - - - 0.000000000000000000000000007026 116.0
PYH1_k127_215414_8 radical SAM domain protein - - - 0.0000000000000000000000005354 106.0
PYH1_k127_2204456_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 363.0
PYH1_k127_2204456_1 - - - - 0.00000000000005628 76.0
PYH1_k127_2204456_2 signal-transduction protein containing cAMP-binding and CBS domains K03281,K08714,K16922 - - 0.0000000000004509 76.0
PYH1_k127_2204456_3 PilZ domain - - - 0.00005706 49.0
PYH1_k127_2227782_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 407.0
PYH1_k127_2227782_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 387.0
PYH1_k127_2227782_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000002218 163.0
PYH1_k127_2227782_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000001002 151.0
PYH1_k127_2236012_0 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 489.0
PYH1_k127_2236012_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 366.0
PYH1_k127_2236012_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000006022 194.0
PYH1_k127_2236012_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000002286 181.0
PYH1_k127_2236012_4 FecR protein - - - 0.0000000000000000000000000000001076 131.0
PYH1_k127_2250560_0 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 561.0
PYH1_k127_2250560_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 524.0
PYH1_k127_2250560_10 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000009765 117.0
PYH1_k127_2250560_11 OsmC-like protein - - - 0.000000000000000000173 95.0
PYH1_k127_2250560_2 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 515.0
PYH1_k127_2250560_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 447.0
PYH1_k127_2250560_4 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 447.0
PYH1_k127_2250560_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 363.0
PYH1_k127_2250560_6 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 359.0
PYH1_k127_2250560_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 301.0
PYH1_k127_2250560_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000001693 254.0
PYH1_k127_2250560_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000002175 178.0
PYH1_k127_2266057_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.514e-194 612.0
PYH1_k127_2266057_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 476.0
PYH1_k127_2266057_2 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 333.0
PYH1_k127_2266057_3 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003031 280.0
PYH1_k127_2266057_4 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002383 261.0
PYH1_k127_2266057_5 ATP cone domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009831 253.0
PYH1_k127_2266057_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000001323 227.0
PYH1_k127_2266057_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000001758 161.0
PYH1_k127_2266057_8 translation release factor activity - - - 0.00000000000000000000000000000000000002827 148.0
PYH1_k127_2266057_9 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000004774 55.0
PYH1_k127_227647_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 480.0
PYH1_k127_227647_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001599 236.0
PYH1_k127_227647_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002173 224.0
PYH1_k127_227647_3 HD domain - - - 0.000000000000000000000000000000000000000000002829 168.0
PYH1_k127_227647_4 protein conserved in bacteria - - - 0.0000000000000000000007315 99.0
PYH1_k127_227647_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000007028 94.0
PYH1_k127_227647_6 S4 domain K14761 - - 0.000000000000000002654 89.0
PYH1_k127_227647_7 Tetratricopeptide repeat - - - 0.00009693 53.0
PYH1_k127_2356394_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 449.0
PYH1_k127_2356394_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 420.0
PYH1_k127_2356394_2 Alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001757 255.0
PYH1_k127_2356394_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000008551 184.0
PYH1_k127_2356394_4 Oligoendopeptidase F K08602 - - 0.0001022 49.0
PYH1_k127_2373055_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 591.0
PYH1_k127_2373055_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 447.0
PYH1_k127_2373055_10 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000004207 130.0
PYH1_k127_2373055_11 Thioredoxin-like - - - 0.00000000000000000000000000002465 123.0
PYH1_k127_2373055_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000003024 106.0
PYH1_k127_2373055_14 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002905 77.0
PYH1_k127_2373055_15 protein secretion K03116,K03117 - - 0.00000000000001968 78.0
PYH1_k127_2373055_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 400.0
PYH1_k127_2373055_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 351.0
PYH1_k127_2373055_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007918 279.0
PYH1_k127_2373055_5 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000001067 225.0
PYH1_k127_2373055_7 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000009877 184.0
PYH1_k127_2373055_8 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000003435 149.0
PYH1_k127_2373055_9 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000003089 141.0
PYH1_k127_2420938_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.367e-252 796.0
PYH1_k127_2420938_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.901e-235 744.0
PYH1_k127_2420938_2 glucosamine-1-phosphate N-acetyltransferase activity K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 426.0
PYH1_k127_2420938_3 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 370.0
PYH1_k127_2420938_4 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
PYH1_k127_2420938_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000006324 162.0
PYH1_k127_2420938_7 transcriptional regulator - - - 0.0000000000000000000000004726 112.0
PYH1_k127_2420938_8 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000002166 104.0
PYH1_k127_2432316_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 596.0
PYH1_k127_2432316_1 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 328.0
PYH1_k127_2432316_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 297.0
PYH1_k127_2432316_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 259.0
PYH1_k127_2432316_4 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000000000000000000000000000000000000000004694 234.0
PYH1_k127_2432316_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000001831 156.0
PYH1_k127_2447250_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 442.0
PYH1_k127_2447250_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 435.0
PYH1_k127_2447250_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000006244 240.0
PYH1_k127_2447250_3 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000000003206 157.0
PYH1_k127_2447250_4 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000001333 155.0
PYH1_k127_2447250_5 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000388 125.0
PYH1_k127_2447250_6 Protein of unknown function (DUF507) - - - 0.000000000000000000000000002242 113.0
PYH1_k127_2447250_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000001617 107.0
PYH1_k127_2447250_8 Protein of unknown function (DUF507) - - - 0.0000000000000000000000306 104.0
PYH1_k127_2447250_9 - - - - 0.00000000000000001646 89.0
PYH1_k127_2504541_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 428.0
PYH1_k127_2504541_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 364.0
PYH1_k127_2504541_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 320.0
PYH1_k127_2504541_3 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 318.0
PYH1_k127_2504541_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 299.0
PYH1_k127_2504541_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000007911 232.0
PYH1_k127_2504541_6 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000000000002569 186.0
PYH1_k127_2504541_7 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000436 160.0
PYH1_k127_2504541_8 phosphorelay signal transduction system - - - 0.0001226 49.0
PYH1_k127_2533461_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 582.0
PYH1_k127_2533461_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000001324 201.0
PYH1_k127_2533461_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000002563 188.0
PYH1_k127_2533461_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000004927 183.0
PYH1_k127_2533461_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000002673 130.0
PYH1_k127_2603535_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
PYH1_k127_2603535_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
PYH1_k127_260377_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 4.683e-282 878.0
PYH1_k127_260377_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.726e-205 662.0
PYH1_k127_260377_10 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000003458 198.0
PYH1_k127_260377_11 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000003774 164.0
PYH1_k127_260377_12 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000002532 131.0
PYH1_k127_260377_13 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 0.00000000000000000000000002453 110.0
PYH1_k127_260377_14 PFAM Smr protein MutS2 - - - 0.00000000000000000000000002893 112.0
PYH1_k127_260377_15 - - - - 0.000000000001216 74.0
PYH1_k127_260377_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 424.0
PYH1_k127_260377_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 376.0
PYH1_k127_260377_4 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 338.0
PYH1_k127_260377_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000001749 259.0
PYH1_k127_260377_6 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000004723 222.0
PYH1_k127_260377_7 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
PYH1_k127_260377_8 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002103 224.0
PYH1_k127_260377_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000007502 222.0
PYH1_k127_2614336_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 378.0
PYH1_k127_2614336_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
PYH1_k127_2614336_2 Belongs to the pirin family K06911 - - 0.000006558 49.0
PYH1_k127_263659_0 Elongation factor G, domain IV K02355 - - 4.853e-293 914.0
PYH1_k127_263659_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 371.0
PYH1_k127_263659_2 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000001182 220.0
PYH1_k127_263659_3 Glutaredoxin - - - 0.000000000000004264 82.0
PYH1_k127_263659_4 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.000000000000008431 82.0
PYH1_k127_263659_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000002359 68.0
PYH1_k127_263659_6 Amidohydrolase family - - - 0.00000000004041 74.0
PYH1_k127_263659_7 SEC-C motif - - - 0.00000009578 55.0
PYH1_k127_263659_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000003622 52.0
PYH1_k127_2653009_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000006309 241.0
PYH1_k127_2653009_1 crp fnr family K01420 - - 0.00000000000000000000000000000000000000000001472 174.0
PYH1_k127_2653009_2 PFAM FMN-binding domain - - - 0.00000000000000000000000000000000000000000001967 177.0
PYH1_k127_2653009_3 Protein of unknown function (DUF2892) - - - 0.000000000000000001558 87.0
PYH1_k127_2655045_0 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 430.0
PYH1_k127_2655045_1 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002611 256.0
PYH1_k127_2655045_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000000000000000000001189 231.0
PYH1_k127_2655045_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002139 218.0
PYH1_k127_2655045_4 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000009142 156.0
PYH1_k127_2655045_5 mRNA catabolic process K18682 - - 0.000000000000000000255 90.0
PYH1_k127_2655585_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1224.0
PYH1_k127_2655585_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 402.0
PYH1_k127_2655585_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003667 260.0
PYH1_k127_2655585_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001069 250.0
PYH1_k127_271075_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
PYH1_k127_271075_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000002687 178.0
PYH1_k127_271075_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000007648 109.0
PYH1_k127_2725341_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
PYH1_k127_2725341_1 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000006869 205.0
PYH1_k127_2725341_2 - - - - 0.0000000000000000000000000000000000000000000000016 179.0
PYH1_k127_2725341_3 - - - - 0.000000000000000000000006686 103.0
PYH1_k127_273070_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 576.0
PYH1_k127_273070_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 537.0
PYH1_k127_273070_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 442.0
PYH1_k127_273070_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
PYH1_k127_273070_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004979 241.0
PYH1_k127_273070_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000001515 149.0
PYH1_k127_273070_6 - - - - 0.0000000000007469 76.0
PYH1_k127_273070_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000886 48.0
PYH1_k127_273070_8 - - - - 0.0003748 51.0
PYH1_k127_2748520_0 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 602.0
PYH1_k127_2748520_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 443.0
PYH1_k127_2748520_2 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 391.0
PYH1_k127_2748520_3 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 390.0
PYH1_k127_2748520_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
PYH1_k127_2754404_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 615.0
PYH1_k127_2754404_1 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000003591 164.0
PYH1_k127_2754404_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000002065 96.0
PYH1_k127_2754404_3 hexose biosynthetic process K01810 - 5.3.1.9 0.000000000000000000218 95.0
PYH1_k127_2780056_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.975e-204 670.0
PYH1_k127_2780056_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 420.0
PYH1_k127_2780056_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 340.0
PYH1_k127_2780056_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
PYH1_k127_2780056_4 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000239 199.0
PYH1_k127_2780056_5 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000000000000000000001364 184.0
PYH1_k127_2780056_6 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000009936 175.0
PYH1_k127_2780056_7 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000252 160.0
PYH1_k127_2801567_0 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 421.0
PYH1_k127_2801567_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
PYH1_k127_2801567_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000011 147.0
PYH1_k127_2801567_3 Protein required for attachment to host cells - - - 0.00000000000000000000000000000002548 132.0
PYH1_k127_2801567_4 Diguanylate cyclase, GGDEF domain - - - 0.000000001158 67.0
PYH1_k127_2805523_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 7.592e-267 848.0
PYH1_k127_2805523_1 Highly conserved protein containing a thioredoxin domain K06888 - - 8.818e-249 786.0
PYH1_k127_2805523_2 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000009043 271.0
PYH1_k127_2826294_0 Heat shock 70 kDa protein K04043 - - 3e-323 998.0
PYH1_k127_2826294_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.268e-229 731.0
PYH1_k127_2826294_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000002289 162.0
PYH1_k127_2826294_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000002823 162.0
PYH1_k127_2826294_12 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000003776 165.0
PYH1_k127_2826294_13 PFAM aminotransferase, class I K04720 - 4.1.1.81 0.000000001039 66.0
PYH1_k127_2826294_2 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 485.0
PYH1_k127_2826294_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 417.0
PYH1_k127_2826294_4 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 406.0
PYH1_k127_2826294_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 408.0
PYH1_k127_2826294_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 346.0
PYH1_k127_2826294_7 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 320.0
PYH1_k127_2826294_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 304.0
PYH1_k127_2826294_9 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 293.0
PYH1_k127_2842014_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.724e-226 705.0
PYH1_k127_2842014_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 595.0
PYH1_k127_2842014_10 RDD family - - - 0.000000000000000000000000002802 115.0
PYH1_k127_2842014_2 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 529.0
PYH1_k127_2842014_3 FAD binding domain K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 494.0
PYH1_k127_2842014_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 344.0
PYH1_k127_2842014_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 325.0
PYH1_k127_2842014_6 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004587 253.0
PYH1_k127_2842014_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000157 202.0
PYH1_k127_2842014_8 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000007189 169.0
PYH1_k127_2842014_9 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000003473 138.0
PYH1_k127_2852674_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 425.0
PYH1_k127_2852674_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000009424 232.0
PYH1_k127_2852674_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000002535 219.0
PYH1_k127_2852674_3 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000008371 215.0
PYH1_k127_2852674_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001482 205.0
PYH1_k127_2852674_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000003464 195.0
PYH1_k127_2852674_6 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000001532 137.0
PYH1_k127_2885772_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 591.0
PYH1_k127_2885772_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 501.0
PYH1_k127_2885772_10 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004536 218.0
PYH1_k127_2885772_11 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000002125 187.0
PYH1_k127_2885772_12 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000001313 108.0
PYH1_k127_2885772_13 Ferric uptake regulator family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000005225 90.0
PYH1_k127_2885772_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000002208 81.0
PYH1_k127_2885772_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 458.0
PYH1_k127_2885772_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 439.0
PYH1_k127_2885772_4 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 413.0
PYH1_k127_2885772_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 416.0
PYH1_k127_2885772_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 352.0
PYH1_k127_2885772_7 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 301.0
PYH1_k127_2885772_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 309.0
PYH1_k127_2885772_9 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001083 257.0
PYH1_k127_2891781_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 352.0
PYH1_k127_2891781_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000251 138.0
PYH1_k127_2925281_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 619.0
PYH1_k127_2925281_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 323.0
PYH1_k127_2925281_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000002051 194.0
PYH1_k127_2925281_5 - - - - 0.00002662 48.0
PYH1_k127_2925281_6 integral membrane protein - - - 0.00003167 49.0
PYH1_k127_2959502_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.475e-280 884.0
PYH1_k127_2959502_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 497.0
PYH1_k127_2959502_10 regulatory protein ArsR K03892 - - 0.0000000000000000000000001621 109.0
PYH1_k127_2959502_11 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000002477 96.0
PYH1_k127_2959502_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000004804 96.0
PYH1_k127_2959502_13 cell cycle K05589,K12065,K13052 - - 0.0000000000000007831 81.0
PYH1_k127_2959502_14 Glycosyl hydrolase family 57 - - - 0.000004319 50.0
PYH1_k127_2959502_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 477.0
PYH1_k127_2959502_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 424.0
PYH1_k127_2959502_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 390.0
PYH1_k127_2959502_5 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 374.0
PYH1_k127_2959502_6 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
PYH1_k127_2959502_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000002412 173.0
PYH1_k127_2959502_8 - - - - 0.00000000000000000000000000000000001474 153.0
PYH1_k127_2959502_9 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000006405 148.0
PYH1_k127_3010214_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 5.149e-199 647.0
PYH1_k127_3010214_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 368.0
PYH1_k127_3010214_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 354.0
PYH1_k127_3010214_3 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005655 254.0
PYH1_k127_3010214_4 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000007306 165.0
PYH1_k127_3010214_5 STAS domain - - - 0.0000000000006774 73.0
PYH1_k127_3018310_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 494.0
PYH1_k127_3018310_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 345.0
PYH1_k127_305466_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1166.0
PYH1_k127_305466_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 422.0
PYH1_k127_305466_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 385.0
PYH1_k127_305466_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 358.0
PYH1_k127_305466_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 314.0
PYH1_k127_305466_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000001132 212.0
PYH1_k127_305466_6 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000003627 96.0
PYH1_k127_305466_7 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000005707 57.0
PYH1_k127_3063376_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 579.0
PYH1_k127_3063376_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
PYH1_k127_3063376_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000967 169.0
PYH1_k127_3063376_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000122 174.0
PYH1_k127_3063376_4 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000009597 111.0
PYH1_k127_3063376_5 - - - - 0.000000000000009597 78.0
PYH1_k127_3113175_0 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 1.051e-263 831.0
PYH1_k127_3113175_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.01e-255 797.0
PYH1_k127_3113175_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000001424 248.0
PYH1_k127_3159310_0 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 390.0
PYH1_k127_3159310_1 Ion channel - - - 0.00000000000000000000000000000000000005098 151.0
PYH1_k127_3159310_2 PFAM Mechanosensitive ion channel - - - 0.0000000286 67.0
PYH1_k127_3160391_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 603.0
PYH1_k127_3160391_1 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 432.0
PYH1_k127_3160391_10 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000003955 209.0
PYH1_k127_3160391_11 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000004776 199.0
PYH1_k127_3160391_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000002473 186.0
PYH1_k127_3160391_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000262 124.0
PYH1_k127_3160391_14 mercury ion transmembrane transporter activity K07213 - - 0.0000000000008603 70.0
PYH1_k127_3160391_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 392.0
PYH1_k127_3160391_3 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 360.0
PYH1_k127_3160391_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
PYH1_k127_3160391_5 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 282.0
PYH1_k127_3160391_6 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000003175 261.0
PYH1_k127_3160391_7 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000002514 229.0
PYH1_k127_3160391_8 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000001138 226.0
PYH1_k127_3160391_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000003769 226.0
PYH1_k127_3163834_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 322.0
PYH1_k127_3163834_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001374 238.0
PYH1_k127_3163834_2 glucan 1,4-alpha-glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000009777 224.0
PYH1_k127_3163834_3 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000001747 185.0
PYH1_k127_3163834_4 LETM1-like protein - - - 0.00004589 53.0
PYH1_k127_3165701_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 558.0
PYH1_k127_3165701_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 428.0
PYH1_k127_3165701_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 357.0
PYH1_k127_3165701_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 319.0
PYH1_k127_3165701_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 258.0
PYH1_k127_3165701_5 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000002191 186.0
PYH1_k127_3165701_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000006911 153.0
PYH1_k127_3228029_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 283.0
PYH1_k127_3228029_1 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003404 224.0
PYH1_k127_3228029_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002014 132.0
PYH1_k127_3228029_3 Protein of unknown function (DUF3106) - - - 0.00008771 51.0
PYH1_k127_3228029_4 AntiSigma factor - - - 0.0001595 51.0
PYH1_k127_3228029_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0004395 45.0
PYH1_k127_3258600_0 Major facilitator Superfamily - - - 3.282e-206 647.0
PYH1_k127_3258600_1 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 513.0
PYH1_k127_3258600_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 320.0
PYH1_k127_3258600_3 High-affinity branched-chain amino acid transport protein (ABC superfamily K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000288 283.0
PYH1_k127_3258600_4 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000005376 160.0
PYH1_k127_3258600_5 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000002801 113.0
PYH1_k127_3258600_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000006368 114.0
PYH1_k127_3273260_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 590.0
PYH1_k127_3273260_1 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 509.0
PYH1_k127_3273260_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 455.0
PYH1_k127_3273260_3 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 317.0
PYH1_k127_3273260_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000004727 177.0
PYH1_k127_3273260_5 O-antigen ligase like membrane protein K18814 - - 0.0008054 51.0
PYH1_k127_327798_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 358.0
PYH1_k127_327798_2 peptidase M24 - - - 0.0000004024 52.0
PYH1_k127_3285821_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 339.0
PYH1_k127_3285821_1 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000299 236.0
PYH1_k127_3285821_2 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000007321 128.0
PYH1_k127_3285821_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000003004 115.0
PYH1_k127_3285821_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000004887 113.0
PYH1_k127_3285821_5 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000008635 98.0
PYH1_k127_3285821_6 NusG domain II K00805 - 2.5.1.30 0.0000000000000000001091 93.0
PYH1_k127_3285821_7 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000007538 78.0
PYH1_k127_3363936_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1209.0
PYH1_k127_3363936_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 384.0
PYH1_k127_3363936_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 384.0
PYH1_k127_3363936_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000006009 227.0
PYH1_k127_3363936_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000001145 199.0
PYH1_k127_3363936_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000003932 172.0
PYH1_k127_3363936_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000001178 128.0
PYH1_k127_3363936_7 PilZ domain - - - 0.000000000001788 74.0
PYH1_k127_3363936_8 YtkA-like - - - 0.00000000001069 72.0
PYH1_k127_3406706_0 AMP binding - - - 0.0000000000000000000000000000000000000000000000005459 179.0
PYH1_k127_3406706_1 - - - - 0.0000000000000000000000000000000001486 142.0
PYH1_k127_3444795_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 415.0
PYH1_k127_3444795_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
PYH1_k127_3444795_2 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000000000000000000000000007382 217.0
PYH1_k127_3444795_3 - - - - 0.0000000000000000000000000000002426 128.0
PYH1_k127_3444795_4 YMGG-like Gly-zipper - - - 0.000000009729 57.0
PYH1_k127_3444795_5 YMGG-like Gly-zipper - - - 0.00002982 53.0
PYH1_k127_3444795_6 Protein of unknown function (DUF2845) - - - 0.000314 48.0
PYH1_k127_3447263_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.716e-220 691.0
PYH1_k127_3447263_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 8.191e-199 635.0
PYH1_k127_3447263_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 579.0
PYH1_k127_3447263_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 354.0
PYH1_k127_3447263_4 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000003559 61.0
PYH1_k127_3461778_0 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000029 229.0
PYH1_k127_3461778_1 PFAM Forkhead-associated protein - - - 0.00000000000000001129 87.0
PYH1_k127_3482055_0 COG0058 Glucan phosphorylase - - - 1.398e-254 796.0
PYH1_k127_3482055_1 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 399.0
PYH1_k127_3482055_10 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000702 160.0
PYH1_k127_3482055_11 PFAM 4Fe-4S K00176 - 1.2.7.3 0.00000000000000001063 86.0
PYH1_k127_3482055_12 to Saccharomyces cerevisiae USO1 (YDL058W) K11436,K20361 GO:0000139,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005795,GO:0005798,GO:0006810,GO:0006886,GO:0006888,GO:0006906,GO:0006996,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0012505,GO:0012506,GO:0012507,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016050,GO:0016192,GO:0022406,GO:0022607,GO:0030133,GO:0030134,GO:0030135,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0031090,GO:0031224,GO:0031410,GO:0031982,GO:0031984,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0035493,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045056,GO:0045184,GO:0046907,GO:0048193,GO:0048211,GO:0048278,GO:0048284,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051649,GO:0061024,GO:0061025,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0090174,GO:0097708,GO:0098588,GO:0098791,GO:0098805,GO:0140056 2.1.1.319 0.00005286 57.0
PYH1_k127_3482055_13 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488,K13819 - - 0.0005067 45.0
PYH1_k127_3482055_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 398.0
PYH1_k127_3482055_3 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 338.0
PYH1_k127_3482055_4 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 306.0
PYH1_k127_3482055_5 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007271 289.0
PYH1_k127_3482055_6 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
PYH1_k127_3482055_7 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002012 240.0
PYH1_k127_3482055_8 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000002725 211.0
PYH1_k127_3482055_9 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000001359 193.0
PYH1_k127_3487605_0 alpha amylase, catalytic region - - - 1.809e-239 747.0
PYH1_k127_3487605_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 296.0
PYH1_k127_3487605_2 - - - - 0.00000000000000000000000000000000000000008557 157.0
PYH1_k127_3496554_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.769e-277 865.0
PYH1_k127_3496554_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
PYH1_k127_3496554_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000001387 196.0
PYH1_k127_3496554_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000006866 184.0
PYH1_k127_3496554_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000001764 138.0
PYH1_k127_3496554_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000003953 94.0
PYH1_k127_3496554_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000003103 85.0
PYH1_k127_354658_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 347.0
PYH1_k127_354658_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000001558 229.0
PYH1_k127_354658_2 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000006093 64.0
PYH1_k127_3554171_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.178e-280 877.0
PYH1_k127_3554171_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 526.0
PYH1_k127_3554171_10 repeat-containing protein - - - 0.00000000000000000002542 101.0
PYH1_k127_3554171_11 Sporulation and spore germination - - - 0.0000000002673 68.0
PYH1_k127_3554171_12 cell wall hydrolase K01448 - 3.5.1.28 0.000000002422 69.0
PYH1_k127_3554171_13 gag-polyprotein putative aspartyl protease K06985 - - 0.0000448 54.0
PYH1_k127_3554171_14 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.000703 42.0
PYH1_k127_3554171_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 381.0
PYH1_k127_3554171_3 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 354.0
PYH1_k127_3554171_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 327.0
PYH1_k127_3554171_5 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 319.0
PYH1_k127_3554171_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000167 253.0
PYH1_k127_3554171_7 - - - - 0.00000000000000000000000000000000000000000000000000002034 196.0
PYH1_k127_3554171_8 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000001439 159.0
PYH1_k127_3554171_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000786 132.0
PYH1_k127_3557192_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 389.0
PYH1_k127_3557192_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 326.0
PYH1_k127_3557192_2 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000006165 243.0
PYH1_k127_3557192_3 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000526 169.0
PYH1_k127_3557192_4 MgtC family K07507 - - 0.000000000000000000000000000000000000001574 155.0
PYH1_k127_3557192_5 PDGLE domain K02007 - - 0.00000000000000000000000000000000000006654 148.0
PYH1_k127_3557192_6 - - - - 0.000000000000000000000009243 104.0
PYH1_k127_3577354_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 579.0
PYH1_k127_3577354_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 550.0
PYH1_k127_3577354_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 384.0
PYH1_k127_360291_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 541.0
PYH1_k127_360291_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000002067 218.0
PYH1_k127_360291_2 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000513 201.0
PYH1_k127_360291_3 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000001412 138.0
PYH1_k127_360291_4 Bacterial regulatory protein, Fis family - - - 0.0000000000000001209 84.0
PYH1_k127_3618860_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1015.0
PYH1_k127_3618860_1 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 378.0
PYH1_k127_3618860_2 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 336.0
PYH1_k127_3618860_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000001949 167.0
PYH1_k127_3618860_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000002281 130.0
PYH1_k127_3618860_5 Transcriptional regulatory protein, C terminal K07670 - - 0.00000000000000000009346 93.0
PYH1_k127_3618860_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000004693 77.0
PYH1_k127_3618860_7 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000001188 66.0
PYH1_k127_3646888_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 4.34e-252 789.0
PYH1_k127_3646888_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 370.0
PYH1_k127_3646888_2 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001111 253.0
PYH1_k127_3646888_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000001119 197.0
PYH1_k127_3646888_4 Domain of unknown function (DUF1858) - - - 0.0000000000000000002274 97.0
PYH1_k127_3646888_5 4Fe-4S binding domain - - - 0.00000003252 56.0
PYH1_k127_366078_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1165.0
PYH1_k127_366078_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 452.0
PYH1_k127_366078_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 402.0
PYH1_k127_366078_3 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 312.0
PYH1_k127_366078_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005549 258.0
PYH1_k127_366078_5 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000001504 145.0
PYH1_k127_366078_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000001426 125.0
PYH1_k127_366078_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000006695 107.0
PYH1_k127_366078_8 protein homooligomerization - - - 0.0001993 51.0
PYH1_k127_3666165_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 540.0
PYH1_k127_3666165_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 349.0
PYH1_k127_3666165_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 346.0
PYH1_k127_3666165_3 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001692 228.0
PYH1_k127_3666165_4 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000001488 186.0
PYH1_k127_3666165_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000003669 175.0
PYH1_k127_3666165_6 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000003443 140.0
PYH1_k127_3666165_7 Glutathione peroxidase - - - 0.0000000000000000000000000000002489 129.0
PYH1_k127_3666165_8 - - - - 0.0000000000000000000000000001294 119.0
PYH1_k127_3666165_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000006945 70.0
PYH1_k127_3667930_0 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 375.0
PYH1_k127_3667930_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 349.0
PYH1_k127_3667930_2 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000305 282.0
PYH1_k127_3667930_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000673 162.0
PYH1_k127_3667930_4 - - - - 0.00002753 52.0
PYH1_k127_3673705_0 export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
PYH1_k127_3673705_1 G-rich domain on putative tyrosine kinase K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000001707 244.0
PYH1_k127_3673705_2 Putative beta-barrel porin 2 K20920 - - 0.0000000000000000000000000000000000002278 158.0
PYH1_k127_3673705_3 signal peptide processing K13280 - 3.4.21.89 0.000000002107 64.0
PYH1_k127_369447_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 611.0
PYH1_k127_369447_1 - - - - 0.0000000000000000000000000000000000000000002896 163.0
PYH1_k127_369447_2 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000002638 149.0
PYH1_k127_3703795_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.068e-197 622.0
PYH1_k127_3703795_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 482.0
PYH1_k127_3703795_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000000009051 187.0
PYH1_k127_3703795_11 RmuC family K09760 - - 0.0000000000001963 76.0
PYH1_k127_3703795_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 411.0
PYH1_k127_3703795_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 385.0
PYH1_k127_3703795_4 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 370.0
PYH1_k127_3703795_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
PYH1_k127_3703795_6 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 310.0
PYH1_k127_3703795_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008471 258.0
PYH1_k127_3703795_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000007215 229.0
PYH1_k127_3703795_9 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000005679 221.0
PYH1_k127_3708126_0 NADH dehydrogenase - - - 1.945e-221 700.0
PYH1_k127_3708126_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 571.0
PYH1_k127_3708126_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 527.0
PYH1_k127_3708126_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 353.0
PYH1_k127_3708126_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
PYH1_k127_3708126_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002556 184.0
PYH1_k127_3708126_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000006871 135.0
PYH1_k127_3708126_7 topology modulation protein - - - 0.00000000000000000000000000002365 126.0
PYH1_k127_3708126_8 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000006045 94.0
PYH1_k127_3708402_0 Sugar (and other) transporter - - - 7.582e-260 811.0
PYH1_k127_3708402_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.642e-242 764.0
PYH1_k127_3708402_2 glycolate transport K14393 - - 2.685e-242 760.0
PYH1_k127_3708402_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.794e-197 635.0
PYH1_k127_3708402_4 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 461.0
PYH1_k127_3708402_5 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 323.0
PYH1_k127_3708402_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000005677 162.0
PYH1_k127_3708402_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000003754 164.0
PYH1_k127_3708402_8 Protein of unknown function, DUF485 - - - 0.00000000000000000000000003384 111.0
PYH1_k127_3708402_9 sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000002247 111.0
PYH1_k127_3712802_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 596.0
PYH1_k127_3712802_1 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000307 258.0
PYH1_k127_3712802_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000002898 231.0
PYH1_k127_3712802_3 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000001597 134.0
PYH1_k127_3714141_0 glycyl-tRNA synthetase, tetrameric type, beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 567.0
PYH1_k127_3714141_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 474.0
PYH1_k127_3714141_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 447.0
PYH1_k127_3714141_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 409.0
PYH1_k127_3714141_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 399.0
PYH1_k127_3714141_5 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 372.0
PYH1_k127_3714141_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000001668 209.0
PYH1_k127_3714141_7 monooxygenase activity - - - 0.00000000000000000000000000000000000000000113 161.0
PYH1_k127_3714141_8 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000004592 155.0
PYH1_k127_3743898_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 414.0
PYH1_k127_3743898_1 ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 284.0
PYH1_k127_3743898_2 FecR protein - - - 0.000000004402 59.0
PYH1_k127_3750477_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1058.0
PYH1_k127_3750477_1 - - - - 0.000000000000000000000000000000000000000000000000000001726 199.0
PYH1_k127_3750477_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000002617 104.0
PYH1_k127_3750477_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000005244 99.0
PYH1_k127_3750477_4 DnaJ molecular chaperone homology domain - - - 0.0004434 51.0
PYH1_k127_3767505_0 PD-(D/E)XK nuclease superfamily - - - 5.195e-229 749.0
PYH1_k127_3767505_1 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 602.0
PYH1_k127_3767505_2 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 465.0
PYH1_k127_3846618_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 314.0
PYH1_k127_3846618_1 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000004916 234.0
PYH1_k127_3846618_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000006342 197.0
PYH1_k127_3862118_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 319.0
PYH1_k127_3862118_1 CGGC - - - 0.00000000000000000000000000000000000000000000000000000000000006526 216.0
PYH1_k127_3862118_2 DGC domain - - - 0.0000000000000000000000000000000000000000000002308 172.0
PYH1_k127_3862118_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000481 160.0
PYH1_k127_3862118_4 - - - - 0.00000000000000001553 95.0
PYH1_k127_3862118_5 - - - - 0.000000002282 66.0
PYH1_k127_3946170_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 522.0
PYH1_k127_3946170_1 response regulator K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 497.0
PYH1_k127_3946170_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.00000000000000000000000000000000000000000000001727 183.0
PYH1_k127_3946170_3 phosphorelay signal transduction system K02437 - - 0.0000000000000000000000000000004975 132.0
PYH1_k127_3946750_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.024e-236 758.0
PYH1_k127_3946750_1 DNA-binding transcription factor activity K03710 - - 0.000000000000000000000000000000000000000000000000000000000005205 215.0
PYH1_k127_3946750_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000002878 196.0
PYH1_k127_3946750_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000009159 191.0
PYH1_k127_3946750_4 IMP dehydrogenase activity - - - 0.0000000000005512 71.0
PYH1_k127_3994519_0 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 353.0
PYH1_k127_3994519_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 337.0
PYH1_k127_3994519_10 integral membrane protein - - - 0.00000004122 63.0
PYH1_k127_3994519_2 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 313.0
PYH1_k127_3994519_3 ATP adenylyltransferase K00988 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002796 284.0
PYH1_k127_3994519_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005762 295.0
PYH1_k127_3994519_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
PYH1_k127_3994519_6 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004495 229.0
PYH1_k127_3994519_7 - - - - 0.000000000000000000000000000000000000000000000003283 181.0
PYH1_k127_3994519_8 response regulator K02485 - - 0.000000000000000000000000000000000000000000000007032 184.0
PYH1_k127_3994519_9 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000006578 144.0
PYH1_k127_4017788_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
PYH1_k127_4017788_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
PYH1_k127_4017788_10 Putative regulatory protein - - - 0.0000000000000000000002008 99.0
PYH1_k127_4017788_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 297.0
PYH1_k127_4017788_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000001204 248.0
PYH1_k127_4017788_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001635 239.0
PYH1_k127_4017788_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000006867 194.0
PYH1_k127_4017788_6 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000001086 182.0
PYH1_k127_4017788_7 Lytic transglycosylase - - - 0.000000000000000000000000000000000000000111 159.0
PYH1_k127_4017788_8 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000001622 128.0
PYH1_k127_4017788_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000016 111.0
PYH1_k127_4053955_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 526.0
PYH1_k127_4053955_1 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 327.0
PYH1_k127_4053955_2 sporulation initiation inhibitor protein Soj K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 310.0
PYH1_k127_4053955_3 NTPase - - - 0.00000000000000000000000000000000000000001916 160.0
PYH1_k127_4053955_4 membrane K09133 - - 0.00000000000000000000000000000000000000006458 157.0
PYH1_k127_4230980_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 400.0
PYH1_k127_4230980_1 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 332.0
PYH1_k127_4230980_2 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
PYH1_k127_4230980_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000002515 174.0
PYH1_k127_4230980_5 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000009608 75.0
PYH1_k127_4262701_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 333.0
PYH1_k127_4262701_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 348.0
PYH1_k127_4262701_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
PYH1_k127_4262701_3 PIN domain K07063 - - 0.000001455 56.0
PYH1_k127_4262701_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0004181 48.0
PYH1_k127_4276627_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 585.0
PYH1_k127_4276627_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 392.0
PYH1_k127_4276627_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 377.0
PYH1_k127_4276627_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 313.0
PYH1_k127_4276627_4 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
PYH1_k127_4276627_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007923 274.0
PYH1_k127_4276627_6 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000001677 242.0
PYH1_k127_4276627_7 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000001912 139.0
PYH1_k127_4303611_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 367.0
PYH1_k127_4303611_1 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 365.0
PYH1_k127_4303611_2 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009126 266.0
PYH1_k127_4303611_3 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000001087 105.0
PYH1_k127_4303611_4 sulfur carrier activity - - - 0.00000000000000000003724 91.0
PYH1_k127_4323793_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 582.0
PYH1_k127_4323793_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 476.0
PYH1_k127_4323793_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000001392 237.0
PYH1_k127_4325575_0 Acyl-protein synthetase, LuxE - - - 3.148e-259 805.0
PYH1_k127_4325575_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 9.678e-199 629.0
PYH1_k127_4325575_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 413.0
PYH1_k127_4325575_4 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000001301 85.0
PYH1_k127_4336674_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 563.0
PYH1_k127_4336674_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 334.0
PYH1_k127_4336674_10 Two component signalling adaptor domain K03408 - - 0.00000000000000001625 93.0
PYH1_k127_4336674_2 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 309.0
PYH1_k127_4336674_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 283.0
PYH1_k127_4336674_4 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003912 263.0
PYH1_k127_4336674_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000002808 251.0
PYH1_k127_4336674_6 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000005283 183.0
PYH1_k127_4336674_7 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000006958 175.0
PYH1_k127_4336674_8 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000533 146.0
PYH1_k127_4336674_9 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000001389 132.0
PYH1_k127_4342166_0 - - - - 0.00000000000000000000000000000000471 139.0
PYH1_k127_4342166_1 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001857 113.0
PYH1_k127_4342166_2 DNA polymerase K02347 - - 0.0000005554 51.0
PYH1_k127_4342166_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713,K07714 - - 0.0000007924 55.0
PYH1_k127_4342727_0 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 541.0
PYH1_k127_4342727_1 PFAM RNA recognition motif - - - 0.000000000000000000000000004259 113.0
PYH1_k127_4343864_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 547.0
PYH1_k127_4343864_1 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001345 237.0
PYH1_k127_4343864_2 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000002213 169.0
PYH1_k127_4343864_3 4 iron, 4 sulfur cluster binding K02574 - - 0.0003365 45.0
PYH1_k127_4392125_0 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 520.0
PYH1_k127_4392125_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 514.0
PYH1_k127_4392125_2 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 305.0
PYH1_k127_4392125_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000286 114.0
PYH1_k127_4392125_4 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000005025 78.0
PYH1_k127_4410741_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.04e-322 1001.0
PYH1_k127_4410741_1 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 426.0
PYH1_k127_4410741_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000001597 247.0
PYH1_k127_4410741_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000005563 147.0
PYH1_k127_4410741_4 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.0000000000000000000000000002613 121.0
PYH1_k127_4410741_5 Evidence 4 Homologs of previously reported genes of - - - 0.000000000001678 69.0
PYH1_k127_4410741_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000005694 61.0
PYH1_k127_4410741_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0002093 53.0
PYH1_k127_4494537_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 375.0
PYH1_k127_4494537_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001512 280.0
PYH1_k127_4494537_10 - - - - 0.00000000000000002274 90.0
PYH1_k127_4494537_11 Tetratricopeptide repeat - - - 0.0000000000000002232 91.0
PYH1_k127_4494537_12 CYTH domain K05873 - 4.6.1.1 0.0000000000001359 79.0
PYH1_k127_4494537_13 - - - - 0.0000439 46.0
PYH1_k127_4494537_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009175 275.0
PYH1_k127_4494537_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000009019 231.0
PYH1_k127_4494537_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000001638 210.0
PYH1_k127_4494537_5 AMP binding - - - 0.00000000000000000000000000000009971 129.0
PYH1_k127_4494537_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000008862 123.0
PYH1_k127_4494537_7 DeoR-like helix-turn-helix domain - - - 0.000000000000000000000000000001143 132.0
PYH1_k127_4494537_8 Diguanylate cyclase - - - 0.00000000000000000000000000005278 127.0
PYH1_k127_4494537_9 Thiamine-binding protein - - - 0.0000000000000000000000000006391 116.0
PYH1_k127_4507919_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.064e-235 736.0
PYH1_k127_4507919_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 414.0
PYH1_k127_4507919_2 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
PYH1_k127_4507919_3 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000000000000000001179 188.0
PYH1_k127_4530841_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1028.0
PYH1_k127_4530841_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.543e-214 674.0
PYH1_k127_4530841_2 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 410.0
PYH1_k127_4530841_3 - K00241 - - 0.000000000000000000000000000000000000000000001152 177.0
PYH1_k127_4551931_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.209e-221 696.0
PYH1_k127_4551931_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 607.0
PYH1_k127_4551931_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002799 270.0
PYH1_k127_4551931_3 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000001035 143.0
PYH1_k127_4551931_4 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000009462 125.0
PYH1_k127_4553071_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 451.0
PYH1_k127_4553071_1 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
PYH1_k127_4553071_2 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 265.0
PYH1_k127_4553071_3 PFAM PhoH-like protein K07175 - - 0.00000000000000000000000000000000000000000000001441 171.0
PYH1_k127_4553071_4 PFAM ferredoxin thioredoxin reductase beta - - - 0.00000000000000000000000000000000000000000003842 165.0
PYH1_k127_4553071_5 PFAM Glutaredoxin K06191 - - 0.0000000000000000000000000000000142 128.0
PYH1_k127_4553071_6 Response regulator receiver domain - - - 0.0000000000000000000000007329 116.0
PYH1_k127_458756_0 Phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 614.0
PYH1_k127_458756_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 575.0
PYH1_k127_458756_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
PYH1_k127_4596478_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.484e-198 623.0
PYH1_k127_4596478_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 503.0
PYH1_k127_4596478_10 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000002458 209.0
PYH1_k127_4596478_11 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000003867 199.0
PYH1_k127_4596478_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000004752 176.0
PYH1_k127_4596478_13 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000001391 173.0
PYH1_k127_4596478_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000003089 124.0
PYH1_k127_4596478_15 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000000005019 118.0
PYH1_k127_4596478_16 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000001039 110.0
PYH1_k127_4596478_17 Tetratricopeptide repeat - - - 0.0000000000000000002732 102.0
PYH1_k127_4596478_18 Roadblock/LC7 domain - - - 0.00000000000000002817 86.0
PYH1_k127_4596478_19 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000002265 63.0
PYH1_k127_4596478_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 355.0
PYH1_k127_4596478_20 Sporulation related domain - - - 0.000008687 58.0
PYH1_k127_4596478_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 335.0
PYH1_k127_4596478_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 314.0
PYH1_k127_4596478_5 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 312.0
PYH1_k127_4596478_6 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003089 289.0
PYH1_k127_4596478_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000009858 243.0
PYH1_k127_4596478_8 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000162 215.0
PYH1_k127_4596478_9 - K07039,K09933 - - 0.0000000000000000000000000000000000000000000000000000000000002411 222.0
PYH1_k127_465474_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.174e-284 897.0
PYH1_k127_465474_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 421.0
PYH1_k127_465474_2 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 317.0
PYH1_k127_465474_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000003891 251.0
PYH1_k127_465474_4 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000001552 245.0
PYH1_k127_465474_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000005831 143.0
PYH1_k127_465474_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000005206 93.0
PYH1_k127_465474_7 Fimbrial assembly protein (PilN) K02663 - - 0.0000000001997 68.0
PYH1_k127_465474_8 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives K02343 - 2.7.7.7 0.00004373 53.0
PYH1_k127_4668079_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.423e-264 822.0
PYH1_k127_4668079_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 522.0
PYH1_k127_4668079_2 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 499.0
PYH1_k127_4668079_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 477.0
PYH1_k127_4668079_4 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 343.0
PYH1_k127_4668079_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 309.0
PYH1_k127_4668079_6 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
PYH1_k127_4668079_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000008017 201.0
PYH1_k127_4668079_8 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000001134 191.0
PYH1_k127_4668079_9 propionyl-CoA carboxylase beta K01966,K01969 - 2.1.3.15,6.4.1.3,6.4.1.4 0.00000000008102 63.0
PYH1_k127_4733214_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 540.0
PYH1_k127_4733214_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 546.0
PYH1_k127_4733214_2 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 428.0
PYH1_k127_4733214_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 349.0
PYH1_k127_4733214_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000002693 191.0
PYH1_k127_476684_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.714e-217 711.0
PYH1_k127_476684_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 429.0
PYH1_k127_476684_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000001538 187.0
PYH1_k127_476684_3 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000003491 132.0
PYH1_k127_476684_4 Thioesterase K07107 - - 0.0000000000000000000000000002691 119.0
PYH1_k127_476684_5 PFAM ABC transporter K02003 - - 0.0000000000000000000000000011 115.0
PYH1_k127_476684_6 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000003091 107.0
PYH1_k127_476684_7 - - - - 0.0000000000000000004006 91.0
PYH1_k127_4810388_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1116.0
PYH1_k127_4810388_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 529.0
PYH1_k127_4810388_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 420.0
PYH1_k127_4810388_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 294.0
PYH1_k127_4810388_4 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001653 271.0
PYH1_k127_4810388_5 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000007119 207.0
PYH1_k127_4810388_6 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000003119 155.0
PYH1_k127_4810388_7 response regulator - - - 0.0000000000000000000000000000000003385 145.0
PYH1_k127_4810388_8 Putative regulatory protein - - - 0.00000001803 58.0
PYH1_k127_4810388_9 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000155 56.0
PYH1_k127_4820159_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 495.0
PYH1_k127_4820159_1 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 440.0
PYH1_k127_4820159_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 324.0
PYH1_k127_4820159_3 TrkA-N domain K03455,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006788 274.0
PYH1_k127_4820159_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000008086 213.0
PYH1_k127_4820159_5 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000000003221 124.0
PYH1_k127_4820159_6 Na dependent nucleoside transporter K03317 - - 0.0000000000000000009921 88.0
PYH1_k127_4820159_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000004069 74.0
PYH1_k127_4820159_8 Nitrate reductase delta subunit - - - 0.000004593 55.0
PYH1_k127_4820384_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1039.0
PYH1_k127_4820384_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.023e-201 640.0
PYH1_k127_4820384_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000002718 221.0
PYH1_k127_4820384_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00003175 51.0
PYH1_k127_4854038_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 536.0
PYH1_k127_4854038_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 449.0
PYH1_k127_4854038_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 411.0
PYH1_k127_4854038_3 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000002274 160.0
PYH1_k127_491663_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 491.0
PYH1_k127_491663_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 422.0
PYH1_k127_491663_2 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000003984 199.0
PYH1_k127_491663_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000003238 120.0
PYH1_k127_4928785_0 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 423.0
PYH1_k127_4928785_1 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 387.0
PYH1_k127_4952317_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1945.0
PYH1_k127_4952317_1 4Fe-4S dicluster domain - - - 3.767e-288 889.0
PYH1_k127_4952317_10 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003086 259.0
PYH1_k127_4952317_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000001228 218.0
PYH1_k127_4952317_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002179 214.0
PYH1_k127_4952317_13 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000000698 185.0
PYH1_k127_4952317_14 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000006203 187.0
PYH1_k127_4952317_15 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000000003792 166.0
PYH1_k127_4952317_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.0000000000000000000000000000000000003256 147.0
PYH1_k127_4952317_17 Protein of unknown function (DUF2752) - - - 0.000000000000000000000000000000000003606 141.0
PYH1_k127_4952317_18 12 heme-binding sites - - - 0.0000000000000000000000000000000000374 143.0
PYH1_k127_4952317_19 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000002623 138.0
PYH1_k127_4952317_2 Surface antigen K07277 - - 2.723e-230 736.0
PYH1_k127_4952317_20 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000006184 129.0
PYH1_k127_4952317_21 response to antibiotic - - - 0.000000000000000000000000000000131 127.0
PYH1_k127_4952317_22 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000001021 123.0
PYH1_k127_4952317_23 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000009642 124.0
PYH1_k127_4952317_24 lyase activity - - - 0.0000000000001704 74.0
PYH1_k127_4952317_25 TM2 domain - - - 0.000005109 55.0
PYH1_k127_4952317_3 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 589.0
PYH1_k127_4952317_4 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 548.0
PYH1_k127_4952317_5 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 503.0
PYH1_k127_4952317_6 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 447.0
PYH1_k127_4952317_7 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 426.0
PYH1_k127_4952317_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 386.0
PYH1_k127_4952317_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 376.0
PYH1_k127_4985097_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 2.366e-229 717.0
PYH1_k127_4985097_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 479.0
PYH1_k127_4985097_2 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 422.0
PYH1_k127_4985097_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 409.0
PYH1_k127_4985097_4 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000005252 186.0
PYH1_k127_4985097_5 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000009272 133.0
PYH1_k127_4985097_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000002297 124.0
PYH1_k127_4985097_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000001822 107.0
PYH1_k127_4995874_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 469.0
PYH1_k127_4995874_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 379.0
PYH1_k127_4995874_2 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000005707 217.0
PYH1_k127_4995874_3 - - - - 0.0000000000000000000000000000000000000000006578 165.0
PYH1_k127_4995874_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001105 115.0
PYH1_k127_4995874_5 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002689 76.0
PYH1_k127_4995874_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000000009916 79.0
PYH1_k127_4995874_7 - - - - 0.0000000006496 64.0
PYH1_k127_5003615_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 3.025e-211 667.0
PYH1_k127_5003615_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 547.0
PYH1_k127_5003615_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 488.0
PYH1_k127_5003615_3 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 332.0
PYH1_k127_5003615_4 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 242.0
PYH1_k127_5003615_5 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000002868 178.0
PYH1_k127_5003615_6 4Fe-4S binding domain - - - 0.000000000000001316 78.0
PYH1_k127_5003615_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000468 70.0
PYH1_k127_5076306_0 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 385.0
PYH1_k127_5076306_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 352.0
PYH1_k127_5076306_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 323.0
PYH1_k127_5076306_3 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000005226 171.0
PYH1_k127_5076306_4 Cyclic nucleotide-monophosphate binding domain K04739 GO:0000003,GO:0000166,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0010721,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030551,GO:0030552,GO:0030554,GO:0030951,GO:0030952,GO:0031032,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141 - 0.000000000008029 76.0
PYH1_k127_5094220_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 602.0
PYH1_k127_5094220_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 544.0
PYH1_k127_5094220_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 435.0
PYH1_k127_5094220_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000002981 229.0
PYH1_k127_5094220_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000001313 205.0
PYH1_k127_5094220_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000003479 147.0
PYH1_k127_5094220_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000002529 142.0
PYH1_k127_5116932_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 310.0
PYH1_k127_5116932_1 Belongs to the precorrin methyltransferase family K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 298.0
PYH1_k127_5116932_2 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000112 213.0
PYH1_k127_5116932_3 Cobalamin synthesis G N-terminal K13541 - 2.1.1.131,3.7.1.12 0.000000000000000000000000000000000000000000001312 175.0
PYH1_k127_5132782_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1665.0
PYH1_k127_5132782_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.77e-199 629.0
PYH1_k127_5132782_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000007707 202.0
PYH1_k127_514128_0 SMART Elongator protein 3 MiaB NifB - - - 8.98e-211 664.0
PYH1_k127_514128_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 427.0
PYH1_k127_514128_10 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000009574 124.0
PYH1_k127_514128_11 Cold shock K03704 - - 0.00000000000000000000000694 102.0
PYH1_k127_514128_12 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000006963 103.0
PYH1_k127_514128_13 Protein of unknown function (DUF3592) - - - 0.000000000003471 78.0
PYH1_k127_514128_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000142 68.0
PYH1_k127_514128_15 Universal stress protein K06149 - - 0.00005192 53.0
PYH1_k127_514128_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00005234 55.0
PYH1_k127_514128_2 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 426.0
PYH1_k127_514128_3 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 369.0
PYH1_k127_514128_5 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
PYH1_k127_514128_6 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 228.0
PYH1_k127_514128_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000002432 237.0
PYH1_k127_514128_8 - - - - 0.000000000000000000000000000000000000000000000000000001157 205.0
PYH1_k127_514128_9 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000007513 204.0
PYH1_k127_5215991_0 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 448.0
PYH1_k127_5215991_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 433.0
PYH1_k127_5215991_2 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000002501 201.0
PYH1_k127_5222643_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 603.0
PYH1_k127_5222643_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 376.0
PYH1_k127_5222643_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 298.0
PYH1_k127_5222643_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000004161 215.0
PYH1_k127_5222643_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000002621 59.0
PYH1_k127_5222937_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1163.0
PYH1_k127_5222937_1 GXGXG motif - - - 5e-324 1014.0
PYH1_k127_5222937_2 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 7.614e-314 971.0
PYH1_k127_5222937_3 Glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 565.0
PYH1_k127_5222937_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 402.0
PYH1_k127_5222937_5 4Fe-4S double cluster binding domain - - - 0.00000000000000000000000000000000000212 143.0
PYH1_k127_5248476_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.454e-247 779.0
PYH1_k127_5248476_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 496.0
PYH1_k127_5248476_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 492.0
PYH1_k127_5248476_3 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000105 109.0
PYH1_k127_5248476_4 Modulates RecA activity K03565 - - 0.0000000000000000002291 94.0
PYH1_k127_526245_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 502.0
PYH1_k127_526245_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 368.0
PYH1_k127_526245_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
PYH1_k127_526245_3 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000005041 200.0
PYH1_k127_526245_4 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000004694 113.0
PYH1_k127_526245_5 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000003299 79.0
PYH1_k127_5268157_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1054.0
PYH1_k127_5268157_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 491.0
PYH1_k127_5268157_10 antisigma factor binding K04749 - - 0.0000000000000000000015 98.0
PYH1_k127_5268157_11 Ion channel K10716 - - 0.00000000000000000001603 94.0
PYH1_k127_5268157_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001363 94.0
PYH1_k127_5268157_13 PFAM Mammalian cell entry related K02067 - - 0.000000000000000008236 94.0
PYH1_k127_5268157_14 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000001375 63.0
PYH1_k127_5268157_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 385.0
PYH1_k127_5268157_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 320.0
PYH1_k127_5268157_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003295 273.0
PYH1_k127_5268157_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
PYH1_k127_5268157_6 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001035 265.0
PYH1_k127_5268157_7 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000006173 237.0
PYH1_k127_5268157_8 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000124 145.0
PYH1_k127_5268157_9 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000001502 106.0
PYH1_k127_5327201_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.108e-281 878.0
PYH1_k127_5327201_1 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 401.0
PYH1_k127_5327201_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 323.0
PYH1_k127_5327201_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 293.0
PYH1_k127_5327201_4 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000001349 253.0
PYH1_k127_5327201_5 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000003537 227.0
PYH1_k127_5327201_6 - - - - 0.0000000000000000000000001577 111.0
PYH1_k127_5343748_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 490.0
PYH1_k127_5343748_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 409.0
PYH1_k127_5343748_10 LemA family K03744 - - 0.000000000000000000000000000000000000000000000005403 177.0
PYH1_k127_5343748_11 OstA-like protein K09774 - - 0.00000000000000000000000000000000002935 140.0
PYH1_k127_5343748_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000007373 139.0
PYH1_k127_5343748_13 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000001532 137.0
PYH1_k127_5343748_14 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000003868 70.0
PYH1_k127_5343748_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 361.0
PYH1_k127_5343748_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
PYH1_k127_5343748_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009399 267.0
PYH1_k127_5343748_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000006219 261.0
PYH1_k127_5343748_6 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000002078 256.0
PYH1_k127_5343748_7 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000617 256.0
PYH1_k127_5343748_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000003738 225.0
PYH1_k127_5343748_9 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000002852 190.0
PYH1_k127_5347173_0 family UPF0324 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 447.0
PYH1_k127_5347173_1 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004115 276.0
PYH1_k127_5347463_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000006572 169.0
PYH1_k127_5347463_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000163 161.0
PYH1_k127_5347463_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000006509 94.0
PYH1_k127_5397232_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1018.0
PYH1_k127_5397232_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 7e-323 1002.0
PYH1_k127_5397232_2 FAD binding domain K00394 - 1.8.99.2 1.844e-197 621.0
PYH1_k127_5397232_3 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 557.0
PYH1_k127_5397232_4 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 396.0
PYH1_k127_5397232_6 Putative zinc- or iron-chelating domain K06940 - - 0.00000003565 57.0
PYH1_k127_5420903_0 acetyl-CoA hydrolase K18288 - - 2.473e-215 686.0
PYH1_k127_5435573_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 501.0
PYH1_k127_5435573_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002466 280.0
PYH1_k127_5435573_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000006876 230.0
PYH1_k127_5435573_3 PFAM PHP domain - - - 0.0000000000000000000000000000000000000000009988 166.0
PYH1_k127_5435573_4 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0000000002945 72.0
PYH1_k127_5443181_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 294.0
PYH1_k127_5443181_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001356 208.0
PYH1_k127_5443181_2 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000001527 190.0
PYH1_k127_5443181_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000005599 184.0
PYH1_k127_5443181_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001438 144.0
PYH1_k127_5443181_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000005871 126.0
PYH1_k127_5443181_6 Belongs to the UPF0109 family K06960 - - 0.0000007245 51.0
PYH1_k127_5451475_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 298.0
PYH1_k127_5451475_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000003131 105.0
PYH1_k127_5451475_2 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000003889 99.0
PYH1_k127_5451475_3 Rhodanese Homology Domain - - - 0.00000000007775 68.0
PYH1_k127_5451475_4 Rhodanese Homology Domain - - - 0.000001232 50.0
PYH1_k127_5460212_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 565.0
PYH1_k127_5460212_1 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 420.0
PYH1_k127_5460212_2 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 331.0
PYH1_k127_5460212_3 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 327.0
PYH1_k127_5460212_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 311.0
PYH1_k127_5460212_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
PYH1_k127_5460212_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000285 235.0
PYH1_k127_5460212_7 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000005247 191.0
PYH1_k127_5460212_8 Peptidase family M48 - - - 0.0000000000000000001498 100.0
PYH1_k127_5460212_9 Belongs to the UPF0434 family K09791 - - 0.000000000000002635 77.0
PYH1_k127_5478159_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 417.0
PYH1_k127_5478159_1 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 349.0
PYH1_k127_5478159_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003579 200.0
PYH1_k127_5478159_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001761 202.0
PYH1_k127_5478159_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000003716 149.0
PYH1_k127_5478159_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000002586 66.0
PYH1_k127_5478159_6 phosphorelay signal transduction system - - - 0.0000000002598 65.0
PYH1_k127_5506077_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 505.0
PYH1_k127_5506077_1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 460.0
PYH1_k127_5506077_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000007749 97.0
PYH1_k127_5506077_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000795 77.0
PYH1_k127_5506077_13 metallopeptidase activity - - - 0.000007172 58.0
PYH1_k127_5506077_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 373.0
PYH1_k127_5506077_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 316.0
PYH1_k127_5506077_4 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000003005 252.0
PYH1_k127_5506077_5 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000000000000000325 238.0
PYH1_k127_5506077_6 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000007169 194.0
PYH1_k127_5506077_7 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
PYH1_k127_5506077_8 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000003242 160.0
PYH1_k127_5506077_9 peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000001868 148.0
PYH1_k127_5531713_0 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 416.0
PYH1_k127_5531713_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
PYH1_k127_5531713_2 nickel cation binding K04651,K19640 - - 0.000000000000000000000000002423 118.0
PYH1_k127_5531713_3 YtxH-like protein - - - 0.000000000000000000000003739 111.0
PYH1_k127_5531713_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000018 65.0
PYH1_k127_5531713_5 Bacterial protein of unknown function (DUF948) - - - 0.000003514 54.0
PYH1_k127_5558991_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 6.655e-225 707.0
PYH1_k127_5558991_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 544.0
PYH1_k127_5558991_10 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.0000000000000000000000000003031 122.0
PYH1_k127_5558991_11 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000003241 101.0
PYH1_k127_5558991_12 cell envelope organization K05807,K08309 - - 0.00000000000009899 80.0
PYH1_k127_5558991_13 Thioredoxin K03672 - 1.8.1.8 0.00009782 53.0
PYH1_k127_5558991_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 530.0
PYH1_k127_5558991_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 518.0
PYH1_k127_5558991_4 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 372.0
PYH1_k127_5558991_5 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 332.0
PYH1_k127_5558991_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009267 281.0
PYH1_k127_5558991_7 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003026 263.0
PYH1_k127_5558991_8 competence protein - - - 0.00000000000000000000000000000000000000000000009537 177.0
PYH1_k127_5558991_9 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000005572 153.0
PYH1_k127_557654_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 445.0
PYH1_k127_557654_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 331.0
PYH1_k127_557654_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000001669 168.0
PYH1_k127_5584800_0 Polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000005564 199.0
PYH1_k127_56266_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005248 244.0
PYH1_k127_56266_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000001298 190.0
PYH1_k127_56266_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000001104 169.0
PYH1_k127_56266_3 Tetratricopeptide repeat - - - 0.0000000000002371 77.0
PYH1_k127_56266_4 Putative zinc-finger - - - 0.00000000003846 74.0
PYH1_k127_5672734_0 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
PYH1_k127_5672734_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
PYH1_k127_5672734_2 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000001821 89.0
PYH1_k127_5701257_0 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 357.0
PYH1_k127_5701257_1 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 308.0
PYH1_k127_5701257_2 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 293.0
PYH1_k127_5701257_3 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000005623 204.0
PYH1_k127_5701257_4 PFAM CBS domain K07182 - - 0.0000000000000000000001034 106.0
PYH1_k127_5713715_0 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 470.0
PYH1_k127_5713715_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 323.0
PYH1_k127_5713715_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000001003 238.0
PYH1_k127_5713715_3 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000004527 104.0
PYH1_k127_5713715_4 Histidine kinase-like ATPase domain - - - 0.000000002097 67.0
PYH1_k127_5727855_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 3.526e-290 912.0
PYH1_k127_5727855_1 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 523.0
PYH1_k127_5727855_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 413.0
PYH1_k127_5727855_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 398.0
PYH1_k127_5727855_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 334.0
PYH1_k127_5727855_5 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 328.0
PYH1_k127_5727855_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000003061 191.0
PYH1_k127_5727855_7 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000005967 135.0
PYH1_k127_5727855_8 CTP:tRNA cytidylyltransferase activity K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.000000000000000000000000003463 125.0
PYH1_k127_5750925_0 ATPase BadF BadG BcrA BcrD type - - - 1.28e-295 932.0
PYH1_k127_5750925_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000001444 213.0
PYH1_k127_5752607_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 597.0
PYH1_k127_5752607_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 526.0
PYH1_k127_5752607_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000009432 216.0
PYH1_k127_5752607_3 SMART Cold shock protein K03704 - - 0.000000000000000000000000005278 112.0
PYH1_k127_5752607_4 Domain of unknown function (DUF4388) - - - 0.00000000000000003031 85.0
PYH1_k127_5791437_0 ABC transporter K06020 - 3.6.3.25 4.399e-298 921.0
PYH1_k127_5791437_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 403.0
PYH1_k127_5791437_2 WYL domain K13573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001485 269.0
PYH1_k127_5791437_3 Serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000005691 87.0
PYH1_k127_5791437_4 - - - - 0.00000001306 63.0
PYH1_k127_5791437_5 Protein of unknown function (DUF3592) - - - 0.00004249 47.0
PYH1_k127_5797316_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.52e-287 892.0
PYH1_k127_5797316_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.039e-195 618.0
PYH1_k127_5797316_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 306.0
PYH1_k127_5797316_3 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008978 259.0
PYH1_k127_5797316_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
PYH1_k127_5797316_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
PYH1_k127_5797316_6 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000003947 202.0
PYH1_k127_5797316_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000003533 134.0
PYH1_k127_5891438_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.808e-295 926.0
PYH1_k127_5891438_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.906e-201 632.0
PYH1_k127_5891438_10 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000009034 139.0
PYH1_k127_5891438_11 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000001902 119.0
PYH1_k127_5891438_12 DUF218 domain - - - 0.000000000000000000000001523 112.0
PYH1_k127_5891438_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000005825 50.0
PYH1_k127_5891438_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 522.0
PYH1_k127_5891438_3 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 341.0
PYH1_k127_5891438_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 336.0
PYH1_k127_5891438_5 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 314.0
PYH1_k127_5891438_6 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 301.0
PYH1_k127_5891438_7 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 293.0
PYH1_k127_5891438_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000288 283.0
PYH1_k127_5891438_9 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000002035 181.0
PYH1_k127_5903006_0 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000002707 243.0
PYH1_k127_5903006_1 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000001546 110.0
PYH1_k127_5921892_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 297.0
PYH1_k127_5921892_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006836 265.0
PYH1_k127_5921892_2 pyridine nucleotide-disulfide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000002932 190.0
PYH1_k127_5921892_3 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000008846 76.0
PYH1_k127_5950198_0 CobB/CobQ-like glutamine amidotransferase domain K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 521.0
PYH1_k127_5950198_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 469.0
PYH1_k127_5950198_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 303.0
PYH1_k127_5950198_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000008589 272.0
PYH1_k127_5950198_4 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
PYH1_k127_5950198_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000599 150.0
PYH1_k127_5989118_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.531e-260 824.0
PYH1_k127_5989118_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.039e-200 639.0
PYH1_k127_5989118_2 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 443.0
PYH1_k127_5989118_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 379.0
PYH1_k127_5989118_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 354.0
PYH1_k127_5989118_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 338.0
PYH1_k127_5989118_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000001267 210.0
PYH1_k127_5989118_7 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000009151 127.0
PYH1_k127_6017032_0 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000006778 216.0
PYH1_k127_6017032_1 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000000005803 175.0
PYH1_k127_6017032_2 OsmC-like protein - - - 0.0000000000003626 76.0
PYH1_k127_602094_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 600.0
PYH1_k127_602094_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 392.0
PYH1_k127_602094_10 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000006735 97.0
PYH1_k127_602094_11 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000006451 89.0
PYH1_k127_602094_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 359.0
PYH1_k127_602094_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 306.0
PYH1_k127_602094_4 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002506 252.0
PYH1_k127_602094_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000007703 174.0
PYH1_k127_602094_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000005625 136.0
PYH1_k127_602094_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000007108 136.0
PYH1_k127_602094_8 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000004101 128.0
PYH1_k127_602094_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000002003 115.0
PYH1_k127_605669_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 4.569e-202 642.0
PYH1_k127_605669_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 462.0
PYH1_k127_605669_2 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 405.0
PYH1_k127_605669_3 - - - - 0.000000000000000000000000000000000000000000000000000000003385 201.0
PYH1_k127_605669_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000002068 200.0
PYH1_k127_605669_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000006297 181.0
PYH1_k127_605669_6 response regulator receiver - - - 0.0000000000000000000000000000000000002303 152.0
PYH1_k127_605669_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000001765 137.0
PYH1_k127_6069132_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 571.0
PYH1_k127_6069132_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 314.0
PYH1_k127_6069132_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000002443 230.0
PYH1_k127_6069132_3 - - - - 0.000000000000000000000000000000000000000000000000000002121 214.0
PYH1_k127_6069132_4 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000009934 147.0
PYH1_k127_6069132_5 LysM domain - - - 0.00000000009876 74.0
PYH1_k127_6069132_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.0000007036 62.0
PYH1_k127_6069132_7 Tetratricopeptide repeat - - - 0.000009409 57.0
PYH1_k127_6070649_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 523.0
PYH1_k127_6070649_1 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 498.0
PYH1_k127_6152012_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 6.112e-214 674.0
PYH1_k127_6152012_1 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 387.0
PYH1_k127_6152012_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002991 254.0
PYH1_k127_6152012_3 NosL - - - 0.00000000000000000000000000000000000000000003524 165.0
PYH1_k127_6152012_4 Predicted membrane protein (DUF2318) - - - 0.00000000000000000002652 96.0
PYH1_k127_6157440_0 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 463.0
PYH1_k127_6157440_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 327.0
PYH1_k127_6157440_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002469 241.0
PYH1_k127_6157440_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000008765 145.0
PYH1_k127_6157440_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000001235 148.0
PYH1_k127_6195352_0 PSP1 C-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001948 243.0
PYH1_k127_6195352_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000003759 203.0
PYH1_k127_6195352_2 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000003755 171.0
PYH1_k127_6195352_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000006874 153.0
PYH1_k127_6281854_0 Protein of unknown function K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 319.0
PYH1_k127_6281854_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000777 118.0
PYH1_k127_6281854_2 Transcriptional regulator, Crp Fnr family - - - 0.00000004117 65.0
PYH1_k127_6313505_0 FAD binding domain K00278 - 1.4.3.16 6.673e-195 622.0
PYH1_k127_6313505_1 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 522.0
PYH1_k127_6313505_11 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000006718 109.0
PYH1_k127_6313505_12 Integrin alpha (beta-propellor repeats). - - - 0.000000001274 70.0
PYH1_k127_6313505_13 PA14 domain - - - 0.000002058 59.0
PYH1_k127_6313505_2 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 515.0
PYH1_k127_6313505_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 412.0
PYH1_k127_6313505_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003295 243.0
PYH1_k127_6313505_5 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000009375 239.0
PYH1_k127_6313505_6 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000007976 232.0
PYH1_k127_6313505_7 lyase activity - - - 0.0000000000000000000000000000000000000000000000001484 200.0
PYH1_k127_6313505_8 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000005402 169.0
PYH1_k127_6313505_9 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000002075 158.0
PYH1_k127_6314405_0 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 519.0
PYH1_k127_6314405_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 412.0
PYH1_k127_6314405_10 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000001368 127.0
PYH1_k127_6314405_11 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000003633 89.0
PYH1_k127_6314405_12 DnaJ molecular chaperone homology domain - - - 0.000000003678 69.0
PYH1_k127_6314405_13 Evidence 5 No homology to any previously reported sequences - - - 0.0000005898 53.0
PYH1_k127_6314405_2 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 387.0
PYH1_k127_6314405_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
PYH1_k127_6314405_4 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
PYH1_k127_6314405_5 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 295.0
PYH1_k127_6314405_6 Serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000001354 243.0
PYH1_k127_6314405_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000003056 224.0
PYH1_k127_6314405_8 ferrous iron binding K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000343 197.0
PYH1_k127_6314405_9 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000005464 183.0
PYH1_k127_6316256_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 358.0
PYH1_k127_6316256_1 Enoyl-(Acyl carrier protein) reductase K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.00000000000000000000000000000000000000000000001915 181.0
PYH1_k127_6316256_2 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000003968 164.0
PYH1_k127_6316256_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000013 149.0
PYH1_k127_6316256_4 Phosphopantetheine attachment site - - - 0.00000000000000000000009534 107.0
PYH1_k127_6316256_5 - - - - 0.00000002463 58.0
PYH1_k127_6337159_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 575.0
PYH1_k127_6337159_1 O-methyltransferase family 3 - - - 0.0000000000000000000000000000000000000000000000000000000004219 211.0
PYH1_k127_6337159_2 - - - - 0.00000000000001849 77.0
PYH1_k127_6337159_3 - - - - 0.00000000000003694 74.0
PYH1_k127_6340107_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 418.0
PYH1_k127_6340107_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 325.0
PYH1_k127_6340107_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000004241 55.0
PYH1_k127_6340107_11 - - - - 0.00001164 54.0
PYH1_k127_6340107_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 312.0
PYH1_k127_6340107_3 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001455 246.0
PYH1_k127_6340107_4 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000001885 220.0
PYH1_k127_6340107_5 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000305 192.0
PYH1_k127_6340107_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000003095 183.0
PYH1_k127_6340107_7 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000001192 127.0
PYH1_k127_6340107_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000271 123.0
PYH1_k127_6340107_9 Putative methyltransferase - - - 0.000000000000000000000004138 116.0
PYH1_k127_6352007_0 Aminotransferase class I and II K14261 - - 3.883e-205 643.0
PYH1_k127_6352007_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 525.0
PYH1_k127_6352007_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
PYH1_k127_6352007_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
PYH1_k127_6352007_4 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000005231 218.0
PYH1_k127_6352007_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000006127 202.0
PYH1_k127_6390817_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.669e-275 860.0
PYH1_k127_6390817_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 540.0
PYH1_k127_6390817_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000005013 271.0
PYH1_k127_6390817_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000002673 113.0
PYH1_k127_6410936_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 567.0
PYH1_k127_6410936_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 487.0
PYH1_k127_6410936_2 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000173 250.0
PYH1_k127_6423735_0 Aconitase C-terminal domain K01681 - 4.2.1.3 2.634e-261 814.0
PYH1_k127_6423735_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 301.0
PYH1_k127_6433340_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 387.0
PYH1_k127_6433340_1 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 339.0
PYH1_k127_6433340_2 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003866 262.0
PYH1_k127_6433340_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000002098 209.0
PYH1_k127_6433340_4 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000001561 193.0
PYH1_k127_6433340_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000119 129.0
PYH1_k127_6433340_6 PFAM DsrE family protein - - - 0.000002003 55.0
PYH1_k127_6544965_0 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 391.0
PYH1_k127_6544965_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 367.0
PYH1_k127_6544965_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000003579 239.0
PYH1_k127_6544965_3 Mur ligase family, catalytic domain K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000585 72.0
PYH1_k127_6563555_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.722e-219 687.0
PYH1_k127_6563555_1 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000008672 169.0
PYH1_k127_6563555_2 histidine kinase HAMP region domain protein - - - 0.0000000001389 73.0
PYH1_k127_6571406_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 575.0
PYH1_k127_6571406_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 520.0
PYH1_k127_6571406_10 type IV pilus modification protein PilV K02458 - - 0.000001308 57.0
PYH1_k127_6571406_11 general secretion pathway protein K02459 - - 0.0000017 58.0
PYH1_k127_6571406_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 350.0
PYH1_k127_6571406_3 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 331.0
PYH1_k127_6571406_4 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000001398 231.0
PYH1_k127_6571406_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000001375 195.0
PYH1_k127_6571406_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000001327 185.0
PYH1_k127_6571406_7 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000003521 154.0
PYH1_k127_6571406_8 PFAM RNA recognition motif - - - 0.000000000000000000000005111 106.0
PYH1_k127_6571406_9 TIGRFAM general secretion pathway protein H K02457 - - 0.00000005619 61.0
PYH1_k127_6587487_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 475.0
PYH1_k127_6587487_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000005254 217.0
PYH1_k127_6587487_2 - - - - 0.0000000000000000000000000000000000000000000001107 172.0
PYH1_k127_6587487_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000009574 134.0
PYH1_k127_6592127_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.597e-253 787.0
PYH1_k127_6592127_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 549.0
PYH1_k127_6592127_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 462.0
PYH1_k127_6592127_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 351.0
PYH1_k127_6592127_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 308.0
PYH1_k127_6592127_5 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000285 207.0
PYH1_k127_6592127_6 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000729 200.0
PYH1_k127_6592127_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000001599 144.0
PYH1_k127_6596812_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 528.0
PYH1_k127_6596812_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 361.0
PYH1_k127_6596812_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 325.0
PYH1_k127_6596812_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000001642 213.0
PYH1_k127_6596812_4 GYD domain - - - 0.000000000000000000000000000000001865 133.0
PYH1_k127_6619762_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 597.0
PYH1_k127_6619762_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 497.0
PYH1_k127_6619762_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 313.0
PYH1_k127_6619762_3 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000006989 121.0
PYH1_k127_6632567_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1067.0
PYH1_k127_6632567_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 587.0
PYH1_k127_6632567_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 365.0
PYH1_k127_6632567_3 Bacterial type II and III secretion system protein K02453,K03219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 351.0
PYH1_k127_6632567_4 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 334.0
PYH1_k127_6632567_5 cyclic nucleotide-binding - - - 0.000000000000000000000000000006723 125.0
PYH1_k127_6632567_6 Protein of unknown function (DUF1189) - - - 0.000000000000000001014 97.0
PYH1_k127_6632567_7 Fimbrial assembly protein (PilN) K02461 - - 0.00000000000001529 86.0
PYH1_k127_6659763_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 519.0
PYH1_k127_6659763_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 375.0
PYH1_k127_6659763_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002854 258.0
PYH1_k127_6666030_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 504.0
PYH1_k127_6666030_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000002499 230.0
PYH1_k127_6666030_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000003206 130.0
PYH1_k127_6666030_3 Chemoreceptor zinc-binding domain - - - 0.0000000000000000004133 91.0
PYH1_k127_6666030_4 binding domain protein - - - 0.0000000008855 61.0
PYH1_k127_6666030_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00004567 47.0
PYH1_k127_6714734_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 3.204e-270 848.0
PYH1_k127_6714734_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.12e-231 724.0
PYH1_k127_6714734_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000003584 163.0
PYH1_k127_6724879_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 342.0
PYH1_k127_6724879_1 MGS-like domain - - - 0.000000000000000000000000000000000000000000000000009647 188.0
PYH1_k127_6724879_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000003383 186.0
PYH1_k127_6726450_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 593.0
PYH1_k127_6726450_1 Starch synthase catalytic K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 532.0
PYH1_k127_6726450_10 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000632 107.0
PYH1_k127_6726450_11 mRNA binding - - - 0.00000000000000000000001523 103.0
PYH1_k127_6726450_12 Belongs to the UPF0235 family K09131 - - 0.000000000000003436 78.0
PYH1_k127_6726450_14 Belongs to the 'phage' integrase family - - - 0.00000217 51.0
PYH1_k127_6726450_15 - - - - 0.0000906 49.0
PYH1_k127_6726450_2 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 308.0
PYH1_k127_6726450_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 301.0
PYH1_k127_6726450_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 292.0
PYH1_k127_6726450_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006045 270.0
PYH1_k127_6726450_6 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000002376 232.0
PYH1_k127_6726450_8 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000003595 142.0
PYH1_k127_6726450_9 Histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000000004954 123.0
PYH1_k127_6728550_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 609.0
PYH1_k127_6728550_1 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 427.0
PYH1_k127_6728550_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000004965 263.0
PYH1_k127_6728550_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000003727 178.0
PYH1_k127_6728550_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000008463 152.0
PYH1_k127_6728550_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000114 56.0
PYH1_k127_6753904_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 424.0
PYH1_k127_6753904_1 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 359.0
PYH1_k127_6753904_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000009846 214.0
PYH1_k127_6753904_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000002763 112.0
PYH1_k127_6753904_4 membrane protein (DUF2207) - - - 0.000000000007541 71.0
PYH1_k127_6797953_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 336.0
PYH1_k127_6797953_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 328.0
PYH1_k127_6797953_2 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002876 286.0
PYH1_k127_6797953_3 FBD - - - 0.0001824 51.0
PYH1_k127_6807382_0 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 3.104e-214 677.0
PYH1_k127_6807382_1 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 370.0
PYH1_k127_6807382_2 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000001222 169.0
PYH1_k127_6866633_0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 4.663e-245 771.0
PYH1_k127_6866633_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 472.0
PYH1_k127_6866633_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 406.0
PYH1_k127_6866633_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000009986 228.0
PYH1_k127_6866633_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000003371 156.0
PYH1_k127_6866633_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000001453 156.0
PYH1_k127_6866633_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000001366 126.0
PYH1_k127_6883242_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 464.0
PYH1_k127_6883242_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 342.0
PYH1_k127_6883242_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000001824 203.0
PYH1_k127_6883242_3 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000003846 165.0
PYH1_k127_6883242_4 iron-sulfur cluster assembly - - - 0.0000000000000000000003987 100.0
PYH1_k127_6883242_5 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000003913 71.0
PYH1_k127_6897930_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 2.051e-209 661.0
PYH1_k127_6897930_1 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001097 219.0
PYH1_k127_6897930_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001591 122.0
PYH1_k127_6897930_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000875 115.0
PYH1_k127_6897930_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000001303 115.0
PYH1_k127_6897930_5 response regulator, receiver - - - 0.00001468 55.0
PYH1_k127_6921909_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 415.0
PYH1_k127_6921909_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 415.0
PYH1_k127_6921909_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 334.0
PYH1_k127_6921909_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 322.0
PYH1_k127_6921909_4 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 296.0
PYH1_k127_6921909_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001942 268.0
PYH1_k127_6921909_6 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000006908 202.0
PYH1_k127_6921909_7 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000005819 144.0
PYH1_k127_6921909_8 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000004652 96.0
PYH1_k127_6921909_9 protein methyltransferase activity K00595 - 2.1.1.132 0.000001624 53.0
PYH1_k127_6994732_0 S-methyl-5'-thioadenosine phosphorylase K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
PYH1_k127_6994732_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 317.0
PYH1_k127_6994732_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 298.0
PYH1_k127_6994732_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000004058 227.0
PYH1_k127_6994732_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000001616 173.0
PYH1_k127_6994732_5 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000002005 109.0
PYH1_k127_6994732_6 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000001341 75.0
PYH1_k127_6997237_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 462.0
PYH1_k127_6997237_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 309.0
PYH1_k127_6997237_2 - - - - 0.000000000000000000000000000000000000000000000000000000006265 206.0
PYH1_k127_6997237_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000002808 188.0
PYH1_k127_6997237_4 Helix-turn-helix domain - - - 0.000000000000000161 89.0
PYH1_k127_6997237_5 Heat shock protein DnaJ domain protein - - - 0.00000001799 67.0
PYH1_k127_6997237_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K09698 - 6.1.1.24 0.00000007531 53.0
PYH1_k127_702605_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 388.0
PYH1_k127_702605_1 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000003681 200.0
PYH1_k127_702605_2 - - - - 0.000000000000000000000007145 106.0
PYH1_k127_7050308_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 591.0
PYH1_k127_7050308_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 344.0
PYH1_k127_7050308_2 Glycosyltransferase, group 2 family protein K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 316.0
PYH1_k127_7050308_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000005804 241.0
PYH1_k127_7062811_0 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 335.0
PYH1_k127_7062811_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000001038 249.0
PYH1_k127_7062811_2 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000002679 243.0
PYH1_k127_7062811_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000001862 162.0
PYH1_k127_7062811_4 Universal stress protein family - - - 0.0000000000000000000000000000000000000001173 155.0
PYH1_k127_7062811_5 energy transducer activity K03832 - - 0.00000000000000000000000000000000000001143 158.0
PYH1_k127_7062811_6 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000001542 152.0
PYH1_k127_7062811_7 proteolysis K03665 - - 0.000000000000000000000000000281 121.0
PYH1_k127_7062811_8 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000001285 108.0
PYH1_k127_7097740_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 424.0
PYH1_k127_7097740_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000005751 207.0
PYH1_k127_7097740_2 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000001732 163.0
PYH1_k127_7097740_3 Peptidase family M50 K11749 - - 0.000000000000000009085 84.0
PYH1_k127_7097906_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.183e-253 798.0
PYH1_k127_7097906_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 296.0
PYH1_k127_7132319_0 - - - - 0.0000000000000000000000000000000000000000000000000001184 203.0
PYH1_k127_7132319_1 - - - - 0.000000001142 65.0
PYH1_k127_7190027_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 559.0
PYH1_k127_7190027_1 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 443.0
PYH1_k127_7190027_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 323.0
PYH1_k127_7190027_3 protein secretion K02460 - - 0.00000000000000000000000000000000000008388 156.0
PYH1_k127_7190027_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000002442 119.0
PYH1_k127_7190027_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000002098 89.0
PYH1_k127_7247443_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 481.0
PYH1_k127_7247443_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 447.0
PYH1_k127_7247443_2 - - - - 0.0000000000004198 72.0
PYH1_k127_7247443_3 Uncharacterised protein family (UPF0158) - - - 0.000000006656 65.0
PYH1_k127_7252920_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 527.0
PYH1_k127_7252920_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002314 270.0
PYH1_k127_7252920_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
PYH1_k127_7252920_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000008043 218.0
PYH1_k127_725311_0 Protein conserved in bacteria - - - 3.666e-234 752.0
PYH1_k127_725311_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 597.0
PYH1_k127_725311_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 322.0
PYH1_k127_725311_3 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008896 256.0
PYH1_k127_725311_4 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000006099 244.0
PYH1_k127_725311_5 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000009443 213.0
PYH1_k127_725311_6 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000002631 121.0
PYH1_k127_725311_8 Regulatory protein, FmdB family - - - 0.0000000000000003299 79.0
PYH1_k127_7257082_0 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 499.0
PYH1_k127_7257082_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 471.0
PYH1_k127_7257082_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000003726 113.0
PYH1_k127_7266146_0 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
PYH1_k127_7266146_1 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001725 254.0
PYH1_k127_7266146_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000009676 246.0
PYH1_k127_7266146_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000004897 138.0
PYH1_k127_7273979_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.113e-284 884.0
PYH1_k127_7273979_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.142e-250 786.0
PYH1_k127_7273979_10 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000000003186 171.0
PYH1_k127_7273979_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000002797 156.0
PYH1_k127_7273979_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000003453 121.0
PYH1_k127_7273979_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 614.0
PYH1_k127_7273979_3 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 460.0
PYH1_k127_7273979_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 321.0
PYH1_k127_7273979_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 303.0
PYH1_k127_7273979_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001085 272.0
PYH1_k127_7273979_7 Mo-molybdopterin cofactor metabolic process K02379 - - 0.0000000000000000000000000000000000000000000000000000000000007115 218.0
PYH1_k127_7273979_8 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000005543 183.0
PYH1_k127_7273979_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000003535 188.0
PYH1_k127_731407_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 497.0
PYH1_k127_731407_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 432.0
PYH1_k127_731407_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 394.0
PYH1_k127_731407_3 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 354.0
PYH1_k127_731407_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 343.0
PYH1_k127_731407_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000691 282.0
PYH1_k127_731407_6 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007299 272.0
PYH1_k127_731407_7 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001911 270.0
PYH1_k127_731407_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000002725 211.0
PYH1_k127_731407_9 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.0000000000000001878 80.0
PYH1_k127_7316141_0 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 325.0
PYH1_k127_7316141_1 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005567 282.0
PYH1_k127_7316141_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009463 248.0
PYH1_k127_7340318_0 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003274 248.0
PYH1_k127_7340318_1 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001995 213.0
PYH1_k127_7340318_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000008025 143.0
PYH1_k127_7414883_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.443e-237 749.0
PYH1_k127_7414883_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 593.0
PYH1_k127_7414883_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 390.0
PYH1_k127_7414883_3 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003703 241.0
PYH1_k127_7414883_4 Domain of unknown function (DUF4912) K09942 - - 0.0000000000006396 81.0
PYH1_k127_7414883_5 Tetratricopeptide repeat - - - 0.0000002191 60.0
PYH1_k127_7414883_6 Protein of unknown function (DUF1318) - - - 0.0002543 44.0
PYH1_k127_7592895_0 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 412.0
PYH1_k127_7592895_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000005313 225.0
PYH1_k127_7592895_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000001944 157.0
PYH1_k127_7592895_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000002786 160.0
PYH1_k127_7592895_4 Sulfurtransferase TusA - - - 0.00000000000000000000001014 103.0
PYH1_k127_7592895_5 Fe-S cluster K04488 - - 0.0000003198 57.0
PYH1_k127_7614206_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 428.0
PYH1_k127_7614206_1 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 357.0
PYH1_k127_7614206_10 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000008877 115.0
PYH1_k127_7614206_11 adenylate cyclase carring two-component hybrid sensor and regulator domains - - - 0.000000000000004801 84.0
PYH1_k127_7614206_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000008396 239.0
PYH1_k127_7614206_3 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000003474 218.0
PYH1_k127_7614206_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
PYH1_k127_7614206_5 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000001515 214.0
PYH1_k127_7614206_6 esterase - - - 0.00000000000000000000000000000000000000000000000000002288 197.0
PYH1_k127_7614206_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000001782 189.0
PYH1_k127_7614206_8 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000005856 167.0
PYH1_k127_7614206_9 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000006192 154.0
PYH1_k127_7671503_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 490.0
PYH1_k127_7671503_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 290.0
PYH1_k127_7671503_2 Belongs to the sirtuin family. Class K12410 - - 0.00000000000000000000000000000000000000000000000000000000000001717 220.0
PYH1_k127_7671503_3 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000004222 183.0
PYH1_k127_7671503_4 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000179 151.0
PYH1_k127_7671503_5 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000005959 140.0
PYH1_k127_7671503_6 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000005569 121.0
PYH1_k127_7683529_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 9.939e-308 951.0
PYH1_k127_7683529_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.639e-248 778.0
PYH1_k127_7683529_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 372.0
PYH1_k127_7683529_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000001324 267.0
PYH1_k127_7683529_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007511 249.0
PYH1_k127_7683529_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000001709 85.0
PYH1_k127_775318_0 Peptidase family M28 - - - 0.0 1037.0
PYH1_k127_775318_1 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 549.0
PYH1_k127_775318_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000001001 151.0
PYH1_k127_775318_3 Ribosomal RNA adenine dimethylase - - - 0.00000000002432 71.0
PYH1_k127_7843395_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 610.0
PYH1_k127_7843395_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000001502 114.0
PYH1_k127_790805_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.027e-265 839.0
PYH1_k127_790805_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 6.267e-194 612.0
PYH1_k127_790805_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 358.0
PYH1_k127_790805_3 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 302.0
PYH1_k127_790805_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000008467 143.0
PYH1_k127_790805_6 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00003979 53.0
PYH1_k127_7925240_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.474e-207 653.0
PYH1_k127_7925240_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000009875 191.0
PYH1_k127_7925240_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000004244 149.0
PYH1_k127_7925240_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000685 74.0
PYH1_k127_7938073_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 484.0
PYH1_k127_7938073_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000002748 190.0
PYH1_k127_7938073_2 Histidine kinase - - - 0.000000323 63.0
PYH1_k127_7974190_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 494.0
PYH1_k127_7974190_1 - - - - 0.0000000000000000000000000000000000000005416 155.0
PYH1_k127_7974190_2 - - - - 0.0003777 48.0
PYH1_k127_7990405_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1016.0
PYH1_k127_7990405_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 307.0
PYH1_k127_7990405_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000005879 157.0
PYH1_k127_7990405_3 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000001491 124.0
PYH1_k127_8023261_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 496.0
PYH1_k127_8023261_1 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 381.0
PYH1_k127_8038879_0 Histidine kinase - - - 1.349e-194 647.0
PYH1_k127_8038879_1 Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 555.0
PYH1_k127_8038879_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000001831 187.0
PYH1_k127_8038879_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000004128 138.0
PYH1_k127_8038879_4 diguanylate cyclase - - - 0.000000000000000000000000000006047 129.0
PYH1_k127_8038879_5 HD domain - - - 0.00000002972 57.0
PYH1_k127_8043993_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000009664 181.0
PYH1_k127_8043993_1 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000004941 159.0
PYH1_k127_8051755_0 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001435 227.0
PYH1_k127_8051755_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000168 212.0
PYH1_k127_8051755_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000002163 192.0
PYH1_k127_8051755_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000007828 180.0
PYH1_k127_8051755_4 - - - - 0.0000000000003364 80.0
PYH1_k127_8051755_5 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.00001401 47.0
PYH1_k127_8057704_1 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000001997 208.0
PYH1_k127_8057704_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000001409 64.0
PYH1_k127_8078962_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 526.0
PYH1_k127_8078962_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
PYH1_k127_8078962_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000929 123.0
PYH1_k127_8083879_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.853e-235 740.0
PYH1_k127_8083879_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000004981 221.0
PYH1_k127_8083879_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000001153 201.0
PYH1_k127_8083879_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000006663 136.0
PYH1_k127_8083879_4 - - - - 0.000000000000000000000565 102.0
PYH1_k127_8129621_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 419.0
PYH1_k127_8129621_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 343.0
PYH1_k127_8129621_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 337.0
PYH1_k127_8129621_3 - - - - 0.00000000000000000000000000000000000000001081 169.0
PYH1_k127_8129621_4 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000002171 126.0
PYH1_k127_8129621_5 - - - - 0.000000000000000006448 89.0
PYH1_k127_8152695_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.23e-247 777.0
PYH1_k127_8152695_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 377.0
PYH1_k127_8152695_2 - - - - 0.000000000000000000002359 102.0
PYH1_k127_8153646_0 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 454.0
PYH1_k127_8153646_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000001023 155.0
PYH1_k127_8202000_0 PFAM peptidase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 411.0
PYH1_k127_8202000_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 312.0
PYH1_k127_8202000_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000001492 226.0
PYH1_k127_8202000_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000001114 224.0
PYH1_k127_8202000_4 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000002018 211.0
PYH1_k127_8202000_5 Stringent starvation protein B K09985 - - 0.00000000000000000000000001351 122.0
PYH1_k127_8215984_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000115 229.0
PYH1_k127_8215984_1 Histidine kinase - - - 0.000000000000000000000000000000000001447 145.0
PYH1_k127_8215984_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000113 136.0
PYH1_k127_8215984_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000006219 122.0
PYH1_k127_8215984_4 - - - - 0.00000000001656 70.0
PYH1_k127_8222295_0 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 363.0
PYH1_k127_8222295_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003792 282.0
PYH1_k127_8222295_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009747 263.0
PYH1_k127_8222295_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000001311 237.0
PYH1_k127_8222295_4 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000003416 144.0
PYH1_k127_8241326_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 552.0
PYH1_k127_8241326_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 357.0
PYH1_k127_8241326_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000001342 222.0
PYH1_k127_8241326_3 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000006092 128.0
PYH1_k127_8241326_4 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000003861 128.0
PYH1_k127_8242246_0 sister chromatid segregation - - - 9.315e-204 646.0
PYH1_k127_8242246_1 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 1.115e-201 634.0
PYH1_k127_8242246_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005103 252.0
PYH1_k127_8242246_3 radical SAM K06871 - - 0.00000000000000000000000000000000000000007936 168.0
PYH1_k127_8242246_4 Bacterial PH domain - - - 0.0000000000000000000000000000000004633 137.0
PYH1_k127_8242246_5 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000178 90.0
PYH1_k127_8242246_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000001571 80.0
PYH1_k127_8242246_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000145 54.0
PYH1_k127_8247559_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 7.619e-234 730.0
PYH1_k127_8247559_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 547.0
PYH1_k127_8247559_2 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001265 276.0
PYH1_k127_8247559_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000003866 147.0
PYH1_k127_8260310_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1292.0
PYH1_k127_8260310_1 - - - - 0.0000000000000000000000000000000000000000000008991 176.0
PYH1_k127_8260310_2 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000003975 135.0
PYH1_k127_8260310_3 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000005817 141.0
PYH1_k127_8260310_4 - - - - 0.00000000000000251 80.0
PYH1_k127_8260310_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0004444 48.0
PYH1_k127_8298628_0 PFAM ferredoxin-dependent glutamate synthase - - - 3.963e-292 903.0
PYH1_k127_8298628_1 glutamate synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 475.0
PYH1_k127_8298628_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 398.0
PYH1_k127_8298628_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 394.0
PYH1_k127_8298628_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
PYH1_k127_8298628_5 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000001262 147.0
PYH1_k127_8298628_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000001281 93.0
PYH1_k127_8302978_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 577.0
PYH1_k127_8302978_1 Pyruvate kinase K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 304.0
PYH1_k127_832270_0 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 302.0
PYH1_k127_832270_1 molybdopterin binding domain - - - 0.0000000000000000000000000000001802 126.0
PYH1_k127_832270_2 PFAM HPP family K07168 - - 0.00000000000000000000000277 102.0
PYH1_k127_8325452_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.422e-205 647.0
PYH1_k127_8325452_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 410.0
PYH1_k127_8325452_2 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 366.0
PYH1_k127_8325452_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 295.0
PYH1_k127_8325452_4 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000001916 203.0
PYH1_k127_8325452_5 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000000005946 183.0
PYH1_k127_8325452_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000005242 99.0
PYH1_k127_8333169_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 3.466e-260 828.0
PYH1_k127_8333169_1 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
PYH1_k127_8348850_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 9.091e-285 882.0
PYH1_k127_8348850_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 407.0
PYH1_k127_8348850_2 SMART ATP-binding region, ATPase-like - - - 0.00000000000000000000001372 104.0
PYH1_k127_8360679_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 327.0
PYH1_k127_8360679_1 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000186 208.0
PYH1_k127_8360679_2 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000000000000000000000000000000000001971 176.0
PYH1_k127_842747_0 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 306.0
PYH1_k127_842747_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000003246 195.0
PYH1_k127_842747_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000194 136.0
PYH1_k127_842747_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000001445 101.0
PYH1_k127_850610_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 576.0
PYH1_k127_850610_1 epimerase dehydratase K19997 - 5.1.3.26 0.00000000000000000000000008257 110.0
PYH1_k127_921993_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 503.0
PYH1_k127_921993_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 494.0
PYH1_k127_921993_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 398.0
PYH1_k127_921993_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 345.0
PYH1_k127_921993_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000006337 239.0
PYH1_k127_921993_5 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000000000000000000000000005283 192.0
PYH1_k127_921993_6 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000003566 102.0
PYH1_k127_963778_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 542.0
PYH1_k127_963778_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 523.0
PYH1_k127_963778_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000004182 229.0
PYH1_k127_963778_11 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000002631 219.0
PYH1_k127_963778_12 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000001833 205.0
PYH1_k127_963778_13 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000424 215.0
PYH1_k127_963778_14 response regulator, receiver K20973 - 2.7.13.3 0.00000000000000000000000000000000000006607 166.0
PYH1_k127_963778_15 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000007721 145.0
PYH1_k127_963778_16 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000003172 149.0
PYH1_k127_963778_17 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000001722 135.0
PYH1_k127_963778_18 cheY-homologous receiver domain - - - 0.00000000000000000000000002545 113.0
PYH1_k127_963778_19 Response regulator receiver domain K03413 - - 0.000000000000000000000001207 110.0
PYH1_k127_963778_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 524.0
PYH1_k127_963778_20 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000003807 107.0
PYH1_k127_963778_21 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000004579 105.0
PYH1_k127_963778_22 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K07714 GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000003527 88.0
PYH1_k127_963778_23 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000003203 74.0
PYH1_k127_963778_24 Chemotaxis protein CheX K03409 - - 0.00000000005917 69.0
PYH1_k127_963778_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 502.0
PYH1_k127_963778_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 466.0
PYH1_k127_963778_5 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 406.0
PYH1_k127_963778_6 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 381.0
PYH1_k127_963778_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 326.0
PYH1_k127_963778_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 314.0
PYH1_k127_963778_9 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
PYH1_k127_96548_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 448.0
PYH1_k127_96548_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000001223 188.0
PYH1_k127_96548_2 adenylate kinase activity K00939,K01939 - 2.7.4.3,6.3.4.4 0.00007549 48.0
PYH1_k127_984950_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 445.0
PYH1_k127_984950_1 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 441.0
PYH1_k127_984950_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 330.0