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Overview

ID MAG03125
Name PYH1_bin.10
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family CSP1-6
Genus AR37
Species
Assembly information
Completeness (%) 82.82
Contamination (%) 1.51
GC content (%) 68.0
N50 (bp) 12,688
Genome size (bp) 3,188,755

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3137

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1021399_0 Peptide ABC transporter substrate-binding protein K02035 - - 2.239e-289 896.0
PYH1_k127_1021399_1 sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 542.0
PYH1_k127_1021399_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 484.0
PYH1_k127_1021399_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 422.0
PYH1_k127_1021399_4 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 382.0
PYH1_k127_1021399_5 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 310.0
PYH1_k127_1021399_6 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
PYH1_k127_1021399_7 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001317 282.0
PYH1_k127_1021399_8 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000795 240.0
PYH1_k127_1021399_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001889 192.0
PYH1_k127_1104442_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 383.0
PYH1_k127_1104442_1 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 377.0
PYH1_k127_1104442_2 NADP-dependent K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 372.0
PYH1_k127_1104442_3 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 345.0
PYH1_k127_1104442_4 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 319.0
PYH1_k127_1104442_5 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000006425 259.0
PYH1_k127_1104442_6 PFAM MOSC domain - - - 0.000000000000000000000000000000002996 145.0
PYH1_k127_1104442_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.000000000000000000000000000818 125.0
PYH1_k127_1152300_0 AcrB/AcrD/AcrF family - - - 0.0 1141.0
PYH1_k127_1152300_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.603e-262 828.0
PYH1_k127_1152300_2 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 484.0
PYH1_k127_1152300_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 411.0
PYH1_k127_1152300_4 abc transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 301.0
PYH1_k127_1152300_5 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 291.0
PYH1_k127_1152300_6 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000003687 251.0
PYH1_k127_1152300_7 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000009475 150.0
PYH1_k127_1152300_8 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000114 94.0
PYH1_k127_1215373_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.083e-262 820.0
PYH1_k127_1215373_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 391.0
PYH1_k127_1215373_2 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 390.0
PYH1_k127_1215373_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
PYH1_k127_1215373_4 PFAM type III effector Hrp-dependent outers K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000000000000000000000000000922 181.0
PYH1_k127_1215373_5 Thioredoxin-like - - - 0.0000000000000000000000000000000001796 139.0
PYH1_k127_1215373_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000259 68.0
PYH1_k127_1238151_0 Hydantoinase/oxoprolinase - - - 1.886e-272 854.0
PYH1_k127_1238151_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.477e-239 763.0
PYH1_k127_1238151_2 Hydantoinase B/oxoprolinase - - - 7.26e-222 697.0
PYH1_k127_1238151_3 PFAM EamA-like transporter family - - - 0.000001012 55.0
PYH1_k127_1270950_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 482.0
PYH1_k127_1270950_1 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000005027 226.0
PYH1_k127_1270950_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.00000000000000000008906 91.0
PYH1_k127_1276595_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 526.0
PYH1_k127_1276595_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 382.0
PYH1_k127_1276595_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 340.0
PYH1_k127_1276595_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 328.0
PYH1_k127_1276595_4 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 322.0
PYH1_k127_1276595_5 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000002594 81.0
PYH1_k127_1276595_6 Ferredoxin-fold anticodon binding domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000001318 74.0
PYH1_k127_1276595_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000007426 77.0
PYH1_k127_1276595_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000001417 72.0
PYH1_k127_1280128_0 ABC transporter transmembrane region - - - 1.114e-297 931.0
PYH1_k127_1280128_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 537.0
PYH1_k127_1280128_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 348.0
PYH1_k127_1280128_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
PYH1_k127_1280128_4 Belongs to the CinA family - - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
PYH1_k127_1280128_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000002593 183.0
PYH1_k127_1280128_6 - - - - 0.000000000000000000000000000004305 138.0
PYH1_k127_1280128_7 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000002001 119.0
PYH1_k127_1280128_8 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000004608 87.0
PYH1_k127_1280362_0 PLD-like domain - - - 1.22e-235 742.0
PYH1_k127_1280362_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 333.0
PYH1_k127_1280362_10 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000002062 162.0
PYH1_k127_1280362_11 - - - - 0.000000000000000000000000000000008248 142.0
PYH1_k127_1280362_2 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
PYH1_k127_1280362_3 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 313.0
PYH1_k127_1280362_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 308.0
PYH1_k127_1280362_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 302.0
PYH1_k127_1280362_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
PYH1_k127_1280362_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 318.0
PYH1_k127_1280362_8 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001619 225.0
PYH1_k127_1280362_9 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000007596 166.0
PYH1_k127_1329467_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 4.487e-252 789.0
PYH1_k127_1329467_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 518.0
PYH1_k127_1329467_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00001094 48.0
PYH1_k127_1342909_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 588.0
PYH1_k127_1342909_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 471.0
PYH1_k127_1342909_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0001502 51.0
PYH1_k127_1342909_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 454.0
PYH1_k127_1342909_3 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007761 265.0
PYH1_k127_1342909_4 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
PYH1_k127_1342909_5 PFAM ROK family protein K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000000000000000000000000000000000000000008498 169.0
PYH1_k127_1342909_6 Protein of unknown function (DUF3105) - - - 0.0000000000000000000000000000000000000000001314 166.0
PYH1_k127_1342909_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000007597 67.0
PYH1_k127_1342909_8 Mut7-C ubiquitin - - - 0.00000002214 60.0
PYH1_k127_1342909_9 Transposase and inactivated derivatives K18996 - - 0.00008191 48.0
PYH1_k127_1349737_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1122.0
PYH1_k127_1349737_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.156e-213 685.0
PYH1_k127_1349737_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 432.0
PYH1_k127_1349737_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000003596 279.0
PYH1_k127_1349737_4 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000003325 225.0
PYH1_k127_1349737_5 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000000005868 153.0
PYH1_k127_1349737_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000003529 133.0
PYH1_k127_1349737_7 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000004487 107.0
PYH1_k127_1349737_8 PFAM ROK family K00845 - 2.7.1.2 0.0000000000125 68.0
PYH1_k127_1349737_9 gag-polyprotein putative aspartyl protease - - - 0.00003043 55.0
PYH1_k127_1352907_0 carbamoyl transferase, NodU family K00612 - - 0.00000000000000000000000000000000000000000000000000000000000002433 217.0
PYH1_k127_1352907_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000239 225.0
PYH1_k127_1352907_2 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000000000000000000000000000000000000001921 187.0
PYH1_k127_1352907_3 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000007082 196.0
PYH1_k127_1352907_4 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000002962 164.0
PYH1_k127_1352907_5 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000002225 144.0
PYH1_k127_1352907_6 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000004123 140.0
PYH1_k127_1352907_7 arsenate reductase K00537 - 1.20.4.1 0.0000006007 57.0
PYH1_k127_1382194_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 389.0
PYH1_k127_1382194_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 275.0
PYH1_k127_1382925_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 2.628e-200 642.0
PYH1_k127_1382925_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
PYH1_k127_1382925_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 430.0
PYH1_k127_1382925_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 384.0
PYH1_k127_1382925_4 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 286.0
PYH1_k127_1419240_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 396.0
PYH1_k127_1419240_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000003714 148.0
PYH1_k127_1419240_2 rRNA small subunit methyltransferase G - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000806 60.0
PYH1_k127_142552_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 450.0
PYH1_k127_142552_1 PFAM LrgB family protein - - - 0.00000000000000000000000000000000000000001359 167.0
PYH1_k127_142552_2 Transposase, IS4 family protein - - - 0.00000000000000000000000000000001802 127.0
PYH1_k127_142552_3 Effector of murein hydrolase LrgA K06518 - - 0.00000000000000000000000001983 113.0
PYH1_k127_142552_4 PFAM ROSMUCR transcriptional regulator - - - 0.000000005503 68.0
PYH1_k127_1454032_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1111.0
PYH1_k127_1454032_1 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 2.269e-285 893.0
PYH1_k127_1454032_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000003962 203.0
PYH1_k127_1454032_11 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000002605 115.0
PYH1_k127_1454032_13 Bacterial PH domain - - - 0.0000003712 59.0
PYH1_k127_1454032_2 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 616.0
PYH1_k127_1454032_3 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 598.0
PYH1_k127_1454032_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 468.0
PYH1_k127_1454032_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 438.0
PYH1_k127_1454032_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 430.0
PYH1_k127_1454032_7 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 393.0
PYH1_k127_1454032_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 307.0
PYH1_k127_1454032_9 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000004465 211.0
PYH1_k127_1514960_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 514.0
PYH1_k127_1514960_1 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 496.0
PYH1_k127_1514960_10 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 293.0
PYH1_k127_1514960_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 292.0
PYH1_k127_1514960_12 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005535 282.0
PYH1_k127_1514960_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 274.0
PYH1_k127_1514960_14 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
PYH1_k127_1514960_15 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
PYH1_k127_1514960_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001934 235.0
PYH1_k127_1514960_17 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000101 242.0
PYH1_k127_1514960_18 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000001063 238.0
PYH1_k127_1514960_19 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000005027 226.0
PYH1_k127_1514960_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 489.0
PYH1_k127_1514960_20 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000009543 217.0
PYH1_k127_1514960_21 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000002823 211.0
PYH1_k127_1514960_22 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000004907 188.0
PYH1_k127_1514960_23 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000002767 188.0
PYH1_k127_1514960_24 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000000000000003977 184.0
PYH1_k127_1514960_25 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000004022 163.0
PYH1_k127_1514960_26 Zn peptidase - - - 0.00000000000000000000000000000000000000444 162.0
PYH1_k127_1514960_27 dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000003417 152.0
PYH1_k127_1514960_28 Smr domain - - - 0.000000000000000000000000000007164 120.0
PYH1_k127_1514960_29 Endoribonuclease L-PSP - - - 0.000000000000000000000000000009934 124.0
PYH1_k127_1514960_3 PFAM extracellular solute-binding protein family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 490.0
PYH1_k127_1514960_30 SnoaL-like domain - - - 0.00000000000000000000000001355 113.0
PYH1_k127_1514960_31 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000000000000005375 107.0
PYH1_k127_1514960_32 SCP-2 sterol transfer family - - - 0.0000000000000000000004997 100.0
PYH1_k127_1514960_33 PFAM EamA-like transporter family - - - 0.00000000000000000001983 104.0
PYH1_k127_1514960_34 EamA-like transporter family - - - 0.000000000000000005705 94.0
PYH1_k127_1514960_35 Peptidase family M23 - - - 0.000000000003565 74.0
PYH1_k127_1514960_36 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.00000000002132 74.0
PYH1_k127_1514960_37 Zn-dependent protease, contains TPR repeats - - - 0.00002656 54.0
PYH1_k127_1514960_4 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 473.0
PYH1_k127_1514960_5 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 462.0
PYH1_k127_1514960_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 409.0
PYH1_k127_1514960_7 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 391.0
PYH1_k127_1514960_8 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 337.0
PYH1_k127_1514960_9 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 309.0
PYH1_k127_1533060_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 444.0
PYH1_k127_1533060_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 304.0
PYH1_k127_1533060_2 COG4796 Type II secretory pathway, component HofQ K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000001006 147.0
PYH1_k127_1541592_0 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 316.0
PYH1_k127_1541592_1 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.00000000000000000000000000000000000000000000000000184 197.0
PYH1_k127_1541592_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000003129 180.0
PYH1_k127_1541592_3 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000004894 130.0
PYH1_k127_157680_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
PYH1_k127_157680_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 429.0
PYH1_k127_157680_2 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 314.0
PYH1_k127_157680_3 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000003794 215.0
PYH1_k127_157680_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000002371 200.0
PYH1_k127_157680_5 Cytochrome oxidase maturation protein cbb3-type - - - 0.0000002005 59.0
PYH1_k127_1579895_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 530.0
PYH1_k127_1579895_1 Beta-lactamase class A K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 312.0
PYH1_k127_1579895_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000001099 243.0
PYH1_k127_1589444_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 1.971e-264 827.0
PYH1_k127_1589444_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 389.0
PYH1_k127_1589444_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 318.0
PYH1_k127_1589444_3 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000004873 222.0
PYH1_k127_1589444_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000001168 198.0
PYH1_k127_1589444_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000002208 181.0
PYH1_k127_1589444_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000006567 94.0
PYH1_k127_1589444_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082 - 1.1.1.193 0.00000000000000001601 96.0
PYH1_k127_163391_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 516.0
PYH1_k127_163391_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
PYH1_k127_163391_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.00000000003634 68.0
PYH1_k127_163391_11 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000002314 57.0
PYH1_k127_163391_12 - - - - 0.00000709 57.0
PYH1_k127_163391_2 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 320.0
PYH1_k127_163391_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 258.0
PYH1_k127_163391_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000002362 239.0
PYH1_k127_163391_5 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000001728 242.0
PYH1_k127_163391_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000001659 233.0
PYH1_k127_163391_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000004883 225.0
PYH1_k127_163391_8 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000005124 207.0
PYH1_k127_163391_9 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000003297 187.0
PYH1_k127_1656845_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169 - 0.0 1127.0
PYH1_k127_1656845_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.158e-221 715.0
PYH1_k127_1656845_10 PFAM Outer membrane efflux protein K15725 - - 0.000000002314 67.0
PYH1_k127_1656845_11 YtkA-like K15727 - - 0.000005387 54.0
PYH1_k127_1656845_2 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 538.0
PYH1_k127_1656845_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 515.0
PYH1_k127_1656845_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 402.0
PYH1_k127_1656845_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 349.0
PYH1_k127_1656845_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
PYH1_k127_1656845_7 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 306.0
PYH1_k127_1656845_8 (2Fe-2S)-binding protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
PYH1_k127_1656845_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000001891 178.0
PYH1_k127_1678521_0 COG3209 Rhs family protein - - - 1.687e-269 889.0
PYH1_k127_1678521_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.326e-236 751.0
PYH1_k127_1678521_10 IPT/TIG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007568 249.0
PYH1_k127_1678521_11 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000001053 233.0
PYH1_k127_1678521_12 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000002703 191.0
PYH1_k127_1678521_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000003584 180.0
PYH1_k127_1678521_14 COG3209 Rhs family protein - - - 0.00000000000000000000000000001798 139.0
PYH1_k127_1678521_15 - - - - 0.0000000000000000000000008588 111.0
PYH1_k127_1678521_18 Methionine biosynthesis protein MetW K00574 - 2.1.1.79 0.000001322 60.0
PYH1_k127_1678521_19 Chemotaxis sensory transducer K03406 - - 0.0000112 58.0
PYH1_k127_1678521_2 thiamine transport K02011 - - 3.863e-234 741.0
PYH1_k127_1678521_3 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 525.0
PYH1_k127_1678521_4 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 419.0
PYH1_k127_1678521_5 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 411.0
PYH1_k127_1678521_6 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 389.0
PYH1_k127_1678521_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 335.0
PYH1_k127_1678521_8 Methionine biosynthesis protein MetW K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 322.0
PYH1_k127_1678521_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002466 260.0
PYH1_k127_1763083_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 471.0
PYH1_k127_1763083_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 433.0
PYH1_k127_1763083_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 363.0
PYH1_k127_1763083_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 327.0
PYH1_k127_1763083_4 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 299.0
PYH1_k127_1763083_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002465 281.0
PYH1_k127_1763083_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001206 293.0
PYH1_k127_1763083_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000006492 245.0
PYH1_k127_1763083_8 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
PYH1_k127_1763083_9 Hydrogenase expression formation protein (HypE) K04655 - - 0.000000000000000000000000000000000000000000000000000000000002584 216.0
PYH1_k127_1765137_0 Large extracellular alpha-helical protein K06894 - - 0.0 1745.0
PYH1_k127_1765137_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 366.0
PYH1_k127_1765137_2 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000004389 225.0
PYH1_k127_1769230_0 Luciferase-like monooxygenase - - - 1.861e-213 668.0
PYH1_k127_1769230_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 602.0
PYH1_k127_1769230_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 606.0
PYH1_k127_1769230_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 333.0
PYH1_k127_1769230_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 295.0
PYH1_k127_1769230_5 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000000000000000000001526 169.0
PYH1_k127_1769230_6 Tetratricopeptide repeat - - - 0.000002294 56.0
PYH1_k127_1782125_0 AMP-binding enzyme C-terminal domain K00666 - - 2.362e-262 815.0
PYH1_k127_1782125_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 351.0
PYH1_k127_1782125_2 PFAM Acetamidase Formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 310.0
PYH1_k127_1782125_3 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005021 259.0
PYH1_k127_1782125_4 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000003582 193.0
PYH1_k127_1782125_5 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000004351 152.0
PYH1_k127_1782125_6 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000397 138.0
PYH1_k127_1782125_7 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000009953 102.0
PYH1_k127_1796977_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 619.0
PYH1_k127_1796977_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000002126 175.0
PYH1_k127_1796977_2 Nodulation protein S (NodS) - - - 0.000000000000000000000000000001023 132.0
PYH1_k127_1796977_3 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000001429 109.0
PYH1_k127_1821336_0 PFAM amidohydrolase K07045 - - 4.628e-205 642.0
PYH1_k127_1821336_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 591.0
PYH1_k127_1821336_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000377 199.0
PYH1_k127_1821336_11 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000005577 197.0
PYH1_k127_1821336_12 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000001113 171.0
PYH1_k127_1821336_13 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000005978 173.0
PYH1_k127_1821336_14 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000001708 168.0
PYH1_k127_1821336_15 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000003937 153.0
PYH1_k127_1821336_16 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000001184 139.0
PYH1_k127_1821336_17 lactate metabolic process - - - 0.00000000000000000000000000000111 134.0
PYH1_k127_1821336_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000008277 89.0
PYH1_k127_1821336_19 cytidylyl-transferase K00983,K21749 - 2.7.7.43,2.7.7.92 0.0000000000003611 76.0
PYH1_k127_1821336_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 489.0
PYH1_k127_1821336_3 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 457.0
PYH1_k127_1821336_4 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 374.0
PYH1_k127_1821336_5 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 368.0
PYH1_k127_1821336_6 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 329.0
PYH1_k127_1821336_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003493 262.0
PYH1_k127_1821336_8 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000363 239.0
PYH1_k127_1821336_9 Family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000134 233.0
PYH1_k127_1890732_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 524.0
PYH1_k127_1890732_1 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 414.0
PYH1_k127_1890732_11 Putative GTP-binding controlling metal-binding K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000002401 94.0
PYH1_k127_1890732_12 Cysteine-rich CPXCG - - - 0.000000000002142 68.0
PYH1_k127_1890732_2 serine-type peptidase activity K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 310.0
PYH1_k127_1890732_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006877 278.0
PYH1_k127_1890732_4 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 269.0
PYH1_k127_1890732_5 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002556 246.0
PYH1_k127_1890732_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002949 241.0
PYH1_k127_1890732_7 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000001108 169.0
PYH1_k127_1890732_8 - - - - 0.00000000000000000000001568 113.0
PYH1_k127_1890732_9 Helix-hairpin-helix motif - - - 0.0000000000000000000003241 101.0
PYH1_k127_1891843_0 Alkyl sulfatase dimerisation - - - 2.541e-259 816.0
PYH1_k127_1891843_1 ATP ADP translocase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 498.0
PYH1_k127_1891843_10 - - - - 0.000000000000000000000000002437 116.0
PYH1_k127_1891843_11 - - - - 0.00000000000000000000009101 102.0
PYH1_k127_1891843_12 Protein of unknown function (DUF3024) - - - 0.00000000001763 71.0
PYH1_k127_1891843_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 336.0
PYH1_k127_1891843_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006029 282.0
PYH1_k127_1891843_4 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000003543 230.0
PYH1_k127_1891843_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000003869 227.0
PYH1_k127_1891843_6 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000001029 201.0
PYH1_k127_1891843_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000001005 151.0
PYH1_k127_1891843_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000002381 138.0
PYH1_k127_1891843_9 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000005556 125.0
PYH1_k127_1899965_0 PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 605.0
PYH1_k127_1899965_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000001119 224.0
PYH1_k127_1899965_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002188 226.0
PYH1_k127_1899965_3 methyltransferase K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000001917 194.0
PYH1_k127_1899965_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000006366 130.0
PYH1_k127_1899965_5 dehydrogenases and related proteins - - - 0.00000000000000000000000002809 122.0
PYH1_k127_1899965_6 Polysaccharide biosynthesis protein - - - 0.0000000000000000003479 102.0
PYH1_k127_1899965_7 Glycosyl transferase, group 1 - - - 0.00000000000000006204 93.0
PYH1_k127_1899965_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.0000000004739 73.0
PYH1_k127_1899965_9 PFAM Methyltransferase type 11 - - - 0.00000001247 66.0
PYH1_k127_1903771_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 368.0
PYH1_k127_1903771_1 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 322.0
PYH1_k127_1903771_2 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 315.0
PYH1_k127_1903771_3 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
PYH1_k127_1903771_4 Radical SAM domain protein K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003356 280.0
PYH1_k127_1903771_5 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000006086 146.0
PYH1_k127_1921629_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.803e-248 779.0
PYH1_k127_1921629_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 573.0
PYH1_k127_1921629_10 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000788 234.0
PYH1_k127_1921629_11 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000006507 172.0
PYH1_k127_1921629_12 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000002005 129.0
PYH1_k127_1921629_13 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000003678 80.0
PYH1_k127_1921629_14 Metallo-beta-lactamase superfamily - - - 0.0000000000004351 76.0
PYH1_k127_1921629_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 481.0
PYH1_k127_1921629_3 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
PYH1_k127_1921629_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 364.0
PYH1_k127_1921629_5 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 318.0
PYH1_k127_1921629_6 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 300.0
PYH1_k127_1921629_7 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000933 287.0
PYH1_k127_1921629_8 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005524 263.0
PYH1_k127_1921629_9 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004281 244.0
PYH1_k127_192772_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 3.053e-227 719.0
PYH1_k127_192772_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 474.0
PYH1_k127_192772_2 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 423.0
PYH1_k127_192772_3 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 290.0
PYH1_k127_192772_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000006101 207.0
PYH1_k127_192772_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000001824 66.0
PYH1_k127_192772_7 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000817 47.0
PYH1_k127_193837_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 419.0
PYH1_k127_193837_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 400.0
PYH1_k127_193837_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000000002056 111.0
PYH1_k127_1948188_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 449.0
PYH1_k127_1948188_1 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 417.0
PYH1_k127_1948188_2 PFAM conserved K07027 - - 0.00000000000000000000000000000007079 144.0
PYH1_k127_1948188_3 ECF sigma factor K03088 - - 0.0000000000000000000000000001249 125.0
PYH1_k127_1997017_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 469.0
PYH1_k127_1997017_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 452.0
PYH1_k127_1997017_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 321.0
PYH1_k127_1997017_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
PYH1_k127_1997017_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000001527 217.0
PYH1_k127_1997017_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000001575 144.0
PYH1_k127_2087326_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 354.0
PYH1_k127_2087326_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 330.0
PYH1_k127_2087326_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005339 283.0
PYH1_k127_2087326_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000009978 153.0
PYH1_k127_2124302_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 424.0
PYH1_k127_2124302_1 branched-chain amino acid transport system, permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 426.0
PYH1_k127_2124302_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 319.0
PYH1_k127_2124302_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 291.0
PYH1_k127_2124302_4 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000002424 252.0
PYH1_k127_2124302_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001907 251.0
PYH1_k127_2124302_6 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH1_k127_2124302_7 dehydratase - - - 0.000000000000000000000000000000002796 142.0
PYH1_k127_2124302_8 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000001904 109.0
PYH1_k127_2128702_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 2.507e-308 959.0
PYH1_k127_2128702_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.97e-204 647.0
PYH1_k127_2128702_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 377.0
PYH1_k127_2128702_3 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000001564 145.0
PYH1_k127_2128702_4 response regulator K02481 - - 0.0000000000000001189 89.0
PYH1_k127_2135532_0 Periplasmic binding protein domain K01999 - - 2.647e-195 619.0
PYH1_k127_2135532_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 409.0
PYH1_k127_2135532_2 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 375.0
PYH1_k127_2135532_3 TIGRFAM ABC transporter, urea, ATP-binding protein, UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000004734 220.0
PYH1_k127_2135532_4 ANTAR K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.000000000005953 66.0
PYH1_k127_214740_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 392.0
PYH1_k127_214740_1 translation release factor activity K03265 - - 0.0000000000000000000000000000000561 138.0
PYH1_k127_214740_2 Universal stress protein - - - 0.000000000000001024 82.0
PYH1_k127_2190173_0 negative regulation of protein lipidation K19294 - - 9.874e-201 633.0
PYH1_k127_2190173_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 428.0
PYH1_k127_2190173_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
PYH1_k127_2190173_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003979 257.0
PYH1_k127_2190173_5 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000001432 185.0
PYH1_k127_2190173_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000003232 158.0
PYH1_k127_2219399_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 390.0
PYH1_k127_2219399_1 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001466 200.0
PYH1_k127_2223378_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 604.0
PYH1_k127_2223378_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 525.0
PYH1_k127_2223378_10 Uncharacterized ACR, COG1430 K09005 - - 0.000003391 56.0
PYH1_k127_2223378_11 - - - - 0.00002805 57.0
PYH1_k127_2223378_2 penicillin-binding protein K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 465.0
PYH1_k127_2223378_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 404.0
PYH1_k127_2223378_4 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 344.0
PYH1_k127_2223378_5 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 290.0
PYH1_k127_2223378_6 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007683 282.0
PYH1_k127_2223378_7 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000008067 226.0
PYH1_k127_2223378_8 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000002309 173.0
PYH1_k127_2223378_9 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000001181 165.0
PYH1_k127_2232390_0 Putative modulator of DNA gyrase K03568 - - 2.846e-208 662.0
PYH1_k127_2232390_1 metallopeptidase activity K03592 - - 1.18e-202 654.0
PYH1_k127_2232390_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000001291 61.0
PYH1_k127_2232390_11 Domain of unknown function (DUF309) K09763 - - 0.00000002301 65.0
PYH1_k127_2232390_2 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 362.0
PYH1_k127_2232390_3 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 333.0
PYH1_k127_2232390_4 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 310.0
PYH1_k127_2232390_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000009742 230.0
PYH1_k127_2232390_6 PEP-CTERM motif - - - 0.000000000000000000000000000000000009102 139.0
PYH1_k127_2232390_7 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000001431 131.0
PYH1_k127_2232390_8 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000009593 115.0
PYH1_k127_2232390_9 RDD family - - - 0.000000000000000003585 91.0
PYH1_k127_2258525_0 major facilitator superfamily - - - 0.0000000000000000000000000000000000000003042 165.0
PYH1_k127_2258525_1 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.00000000000000000000000000000000000001802 156.0
PYH1_k127_2258525_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000005081 115.0
PYH1_k127_2258525_3 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000009893 107.0
PYH1_k127_2258525_4 Thioesterase superfamily - - - 0.00004603 54.0
PYH1_k127_2270324_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 476.0
PYH1_k127_2270324_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 421.0
PYH1_k127_2270324_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000001468 96.0
PYH1_k127_2270324_11 Glycine-zipper domain - - - 0.00001194 57.0
PYH1_k127_2270324_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 381.0
PYH1_k127_2270324_3 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
PYH1_k127_2270324_4 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000001921 237.0
PYH1_k127_2270324_5 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000004643 247.0
PYH1_k127_2270324_6 dehydratase - - - 0.0000000000000000000000000000000000000000000002029 178.0
PYH1_k127_2270324_7 - - - - 0.00000000000000000000000000000000000000000002763 166.0
PYH1_k127_2270324_8 PFAM Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000006948 161.0
PYH1_k127_2270324_9 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000157 117.0
PYH1_k127_2287510_0 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 370.0
PYH1_k127_2287510_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 340.0
PYH1_k127_2287510_2 Branched-chain amino acid ABC transporter ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000001509 205.0
PYH1_k127_2287510_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000009717 77.0
PYH1_k127_2287510_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000005565 62.0
PYH1_k127_2287510_5 Belongs to the 'phage' integrase family - - - 0.0003134 46.0
PYH1_k127_2345531_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 473.0
PYH1_k127_2345531_1 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
PYH1_k127_2345531_10 amine dehydrogenase activity - - - 0.000000000000000000000001388 107.0
PYH1_k127_2345531_11 amine dehydrogenase activity - - - 0.00000002687 58.0
PYH1_k127_2345531_2 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 305.0
PYH1_k127_2345531_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 297.0
PYH1_k127_2345531_4 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003998 269.0
PYH1_k127_2345531_5 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005268 251.0
PYH1_k127_2345531_6 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000002208 198.0
PYH1_k127_2345531_7 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000354 147.0
PYH1_k127_2345531_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000007982 134.0
PYH1_k127_2345531_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000003485 112.0
PYH1_k127_2356539_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000004046 219.0
PYH1_k127_2356539_1 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000003416 201.0
PYH1_k127_2356539_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000002659 206.0
PYH1_k127_2356539_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000006165 174.0
PYH1_k127_2356539_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000003729 126.0
PYH1_k127_2356539_5 maleate cis-trans isomerase K01799 - 5.2.1.1 0.00000000001685 70.0
PYH1_k127_24052_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 392.0
PYH1_k127_24052_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 319.0
PYH1_k127_24052_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001896 98.0
PYH1_k127_24052_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000006037 106.0
PYH1_k127_24052_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000003206 80.0
PYH1_k127_24052_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000004365 66.0
PYH1_k127_24052_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000001371 240.0
PYH1_k127_24052_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000115 211.0
PYH1_k127_24052_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001266 187.0
PYH1_k127_24052_5 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000005677 182.0
PYH1_k127_24052_6 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001218 165.0
PYH1_k127_24052_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000002711 134.0
PYH1_k127_24052_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004241 131.0
PYH1_k127_24052_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000437 123.0
PYH1_k127_240555_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2166.0
PYH1_k127_240555_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 2.514e-255 810.0
PYH1_k127_240555_10 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 419.0
PYH1_k127_240555_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 401.0
PYH1_k127_240555_12 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 354.0
PYH1_k127_240555_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 349.0
PYH1_k127_240555_14 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 308.0
PYH1_k127_240555_15 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 304.0
PYH1_k127_240555_16 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002129 280.0
PYH1_k127_240555_17 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007646 274.0
PYH1_k127_240555_18 COG0583 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000176 266.0
PYH1_k127_240555_19 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007265 263.0
PYH1_k127_240555_2 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 2.65e-241 752.0
PYH1_k127_240555_20 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000002672 244.0
PYH1_k127_240555_21 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001429 192.0
PYH1_k127_240555_22 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001257 163.0
PYH1_k127_240555_23 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000005941 158.0
PYH1_k127_240555_24 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000001942 159.0
PYH1_k127_240555_25 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000003303 152.0
PYH1_k127_240555_26 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000000000005678 128.0
PYH1_k127_240555_27 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.0000000000000000002133 92.0
PYH1_k127_240555_28 - - - - 0.0000000000001398 74.0
PYH1_k127_240555_29 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000001614 72.0
PYH1_k127_240555_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 5.509e-231 731.0
PYH1_k127_240555_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 2.315e-194 616.0
PYH1_k127_240555_5 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 598.0
PYH1_k127_240555_6 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 459.0
PYH1_k127_240555_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 461.0
PYH1_k127_240555_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 439.0
PYH1_k127_240555_9 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 426.0
PYH1_k127_2461177_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.473e-297 931.0
PYH1_k127_2461177_1 DNA polymerase X family K02347,K04477 - - 1.19e-234 740.0
PYH1_k127_2461177_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 302.0
PYH1_k127_2461177_3 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000003523 168.0
PYH1_k127_2461177_4 Universal stress protein family - - - 0.0000000004695 60.0
PYH1_k127_2530983_0 PFAM Mammalian cell entry related domain protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 560.0
PYH1_k127_2530983_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 529.0
PYH1_k127_2530983_10 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000000933 141.0
PYH1_k127_2530983_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000006261 131.0
PYH1_k127_2530983_12 Virulence factor BrkB K07058 - - 0.0000000000000001515 91.0
PYH1_k127_2530983_13 - - - - 0.000000000002521 75.0
PYH1_k127_2530983_14 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00002409 48.0
PYH1_k127_2530983_2 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
PYH1_k127_2530983_3 response to abiotic stimulus K06867 GO:0008150,GO:0009314,GO:0009628,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000001869 248.0
PYH1_k127_2530983_4 paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006567 244.0
PYH1_k127_2530983_5 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000025 231.0
PYH1_k127_2530983_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
PYH1_k127_2530983_7 CHRD domain - - - 0.00000000000000000000000000000000000000000000000000000000005743 210.0
PYH1_k127_2530983_8 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000001676 201.0
PYH1_k127_2530983_9 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000009485 161.0
PYH1_k127_2545384_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 330.0
PYH1_k127_2545384_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000004539 188.0
PYH1_k127_2545384_2 Protein of unknown function (DUF983) - - - 0.000000000000000000000000002949 114.0
PYH1_k127_2545384_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000003277 105.0
PYH1_k127_2545384_4 pilus assembly protein PilW - - - 0.0000003848 59.0
PYH1_k127_2613799_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 500.0
PYH1_k127_2613799_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 476.0
PYH1_k127_2613799_2 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 362.0
PYH1_k127_2613799_3 - - - - 0.000000000000000000000000000000000000000000000000000000001068 212.0
PYH1_k127_2613799_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000918 154.0
PYH1_k127_2613799_5 Tetratricopeptide repeat - - - 0.000000000000000000000000007379 119.0
PYH1_k127_2613799_6 Phosphate acyltransferases - - - 0.000000000000000000000001234 109.0
PYH1_k127_2616113_0 Heat shock 70 kDa protein K04043 - - 1.301e-290 904.0
PYH1_k127_2616113_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000006359 76.0
PYH1_k127_2628476_0 Carboxyl transferase domain - - - 1.274e-209 662.0
PYH1_k127_2628476_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000865 144.0
PYH1_k127_2628476_2 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000001663 106.0
PYH1_k127_2628476_3 - - - - 0.00000000015 68.0
PYH1_k127_2629423_0 heat shock protein 70 K04043,K04044 - - 7.183e-198 634.0
PYH1_k127_2629423_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 569.0
PYH1_k127_2629423_10 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 314.0
PYH1_k127_2629423_11 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000762 282.0
PYH1_k127_2629423_12 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 272.0
PYH1_k127_2629423_13 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
PYH1_k127_2629423_14 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000476 261.0
PYH1_k127_2629423_15 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 258.0
PYH1_k127_2629423_16 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000002924 256.0
PYH1_k127_2629423_17 oxidoreductase activity K07114,K16257 - - 0.00000000000000000000000000000000000000000000000000000000000000000001553 267.0
PYH1_k127_2629423_18 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000003435 239.0
PYH1_k127_2629423_19 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000003473 225.0
PYH1_k127_2629423_2 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 551.0
PYH1_k127_2629423_20 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000001421 210.0
PYH1_k127_2629423_21 Transcriptional regulator - - - 0.000000000000000000000000000000000004749 142.0
PYH1_k127_2629423_22 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000001128 148.0
PYH1_k127_2629423_23 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564 - 0.0000000000000000000000000000002158 126.0
PYH1_k127_2629423_24 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000001418 125.0
PYH1_k127_2629423_25 DnaJ molecular chaperone homology domain K04082 - - 0.000000000000000000000000002065 121.0
PYH1_k127_2629423_26 PFAM NifU-like N terminal domain K04488 - - 0.0000000000000000000001899 104.0
PYH1_k127_2629423_27 Iron-sulphur cluster assembly - - - 0.000000000000000000000582 102.0
PYH1_k127_2629423_28 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000008328 100.0
PYH1_k127_2629423_29 Pup-like protein K13570 - - 0.000000000000002014 77.0
PYH1_k127_2629423_3 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 533.0
PYH1_k127_2629423_31 glutaredoxin-like protein, YruB-family - - - 0.00000000001761 66.0
PYH1_k127_2629423_32 regulatory protein, FmdB family - - - 0.0000000000512 65.0
PYH1_k127_2629423_33 Putative zinc-finger - - - 0.00000000007654 67.0
PYH1_k127_2629423_34 TPR repeat - - - 0.000000006763 68.0
PYH1_k127_2629423_35 Helix-turn-helix domain - - - 0.00004956 48.0
PYH1_k127_2629423_36 LysM domain - - - 0.0001317 54.0
PYH1_k127_2629423_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 460.0
PYH1_k127_2629423_5 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 391.0
PYH1_k127_2629423_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 376.0
PYH1_k127_2629423_7 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 351.0
PYH1_k127_2629423_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 340.0
PYH1_k127_2629423_9 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 349.0
PYH1_k127_265668_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.413e-282 878.0
PYH1_k127_265668_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 497.0
PYH1_k127_265668_10 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000004598 245.0
PYH1_k127_265668_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000005629 182.0
PYH1_k127_265668_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000196 128.0
PYH1_k127_265668_2 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 462.0
PYH1_k127_265668_3 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 400.0
PYH1_k127_265668_4 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 392.0
PYH1_k127_265668_5 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 394.0
PYH1_k127_265668_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
PYH1_k127_265668_7 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 299.0
PYH1_k127_265668_8 COG0778 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 293.0
PYH1_k127_265668_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003658 271.0
PYH1_k127_2692328_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.394e-218 705.0
PYH1_k127_2692328_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.745e-216 684.0
PYH1_k127_2692328_10 ABC transporter substrate binding protein K01989 - - 0.00000000000319 66.0
PYH1_k127_2692328_11 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000001221 61.0
PYH1_k127_2692328_12 Cytochrome c-type biogenesis protein K02200 - - 0.00003972 53.0
PYH1_k127_2692328_13 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00004432 55.0
PYH1_k127_2692328_2 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 457.0
PYH1_k127_2692328_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 449.0
PYH1_k127_2692328_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 316.0
PYH1_k127_2692328_5 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 284.0
PYH1_k127_2692328_6 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000005024 271.0
PYH1_k127_2692328_7 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006458 259.0
PYH1_k127_2692328_8 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000000000001701 189.0
PYH1_k127_2692328_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000005166 109.0
PYH1_k127_2706304_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 296.0
PYH1_k127_2706304_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000001692 219.0
PYH1_k127_2706304_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000004873 228.0
PYH1_k127_2706304_3 - - - - 0.000000000000000000681 102.0
PYH1_k127_270861_0 elongation factor G K02355 - - 2.817e-226 720.0
PYH1_k127_270861_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 2.576e-213 689.0
PYH1_k127_270861_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
PYH1_k127_270861_11 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000004682 212.0
PYH1_k127_270861_12 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000005756 184.0
PYH1_k127_270861_13 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000003418 190.0
PYH1_k127_270861_14 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000004437 164.0
PYH1_k127_270861_15 - - - - 0.000000000000000000001853 98.0
PYH1_k127_270861_16 other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000004205 86.0
PYH1_k127_270861_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 523.0
PYH1_k127_270861_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 385.0
PYH1_k127_270861_4 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 370.0
PYH1_k127_270861_5 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 317.0
PYH1_k127_270861_6 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 319.0
PYH1_k127_270861_7 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 302.0
PYH1_k127_270861_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 291.0
PYH1_k127_270861_9 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002652 276.0
PYH1_k127_2742581_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 605.0
PYH1_k127_2742581_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 305.0
PYH1_k127_2742581_2 transposition K07497 - - 0.000000000000000000000000000499 115.0
PYH1_k127_2742581_3 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000005688 68.0
PYH1_k127_2742581_4 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000002727 63.0
PYH1_k127_2742613_0 Beta-lactamase - - - 4.539e-203 658.0
PYH1_k127_2742613_1 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 604.0
PYH1_k127_2742613_2 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 361.0
PYH1_k127_2742613_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
PYH1_k127_2742613_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009183 247.0
PYH1_k127_2742613_5 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.0000000000000000000000000000000007966 142.0
PYH1_k127_2802681_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 590.0
PYH1_k127_2802681_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 465.0
PYH1_k127_2802681_10 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000007011 123.0
PYH1_k127_2802681_11 iron-sulfur cluster assembly K07400,K13628,K15724 - - 0.000000000000000000000000006734 115.0
PYH1_k127_2802681_12 Pfam:DUF385 - - - 0.0000000000000000007368 92.0
PYH1_k127_2802681_13 PFAM Vitamin K epoxide reductase - - - 0.000000000000000007451 85.0
PYH1_k127_2802681_14 RDD family - - - 0.000000000000693 77.0
PYH1_k127_2802681_15 COG0457 FOG TPR repeat - - - 0.00000008343 59.0
PYH1_k127_2802681_16 Peptidase family M48 - - - 0.00002868 55.0
PYH1_k127_2802681_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 425.0
PYH1_k127_2802681_3 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
PYH1_k127_2802681_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 289.0
PYH1_k127_2802681_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH1_k127_2802681_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000001051 206.0
PYH1_k127_2802681_7 transglycosylase K08309 - - 0.00000000000000000000000000000000000000000004483 181.0
PYH1_k127_2802681_8 - - - - 0.000000000000000000000000000000000000006391 151.0
PYH1_k127_2802681_9 quinone binding K12057,K22278 - 3.5.1.104 0.00000000000000000000000000000506 128.0
PYH1_k127_2864869_0 aminocarboxymuconate-semialdehyde decarboxylase activity K03392 GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 293.0
PYH1_k127_2864869_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 296.0
PYH1_k127_2864869_2 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007562 287.0
PYH1_k127_2864869_3 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000153 236.0
PYH1_k127_2864869_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000001739 233.0
PYH1_k127_2864869_5 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000279 237.0
PYH1_k127_2864869_6 PFAM Patatin - - - 0.000000000000000000000000000000000000000000000000002268 195.0
PYH1_k127_2864869_7 photosystem I assembly BtpA K06971 - - 0.000000000000001653 77.0
PYH1_k127_2869088_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 471.0
PYH1_k127_2869088_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 372.0
PYH1_k127_2869088_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002638 283.0
PYH1_k127_2869088_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000003109 201.0
PYH1_k127_2869088_4 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000008144 151.0
PYH1_k127_2869088_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000001661 102.0
PYH1_k127_2922107_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
PYH1_k127_2922107_1 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.00000000000000000000000000003846 121.0
PYH1_k127_2923295_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 297.0
PYH1_k127_2923295_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 278.0
PYH1_k127_2923295_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002482 270.0
PYH1_k127_2923295_3 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000003106 213.0
PYH1_k127_2923295_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000001593 160.0
PYH1_k127_2923295_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000003061 157.0
PYH1_k127_2923295_6 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000001734 136.0
PYH1_k127_2923295_7 Methyltransferase FkbM domain - - - 0.000000000000000000005924 105.0
PYH1_k127_2940510_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 484.0
PYH1_k127_2940510_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 407.0
PYH1_k127_2940510_2 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
PYH1_k127_2940510_3 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 377.0
PYH1_k127_2940510_4 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000003419 153.0
PYH1_k127_294402_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.507e-296 917.0
PYH1_k127_294402_1 Major Facilitator Superfamily - - - 2.694e-205 646.0
PYH1_k127_294402_10 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 304.0
PYH1_k127_294402_11 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 307.0
PYH1_k127_294402_12 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 318.0
PYH1_k127_294402_13 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 301.0
PYH1_k127_294402_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008096 258.0
PYH1_k127_294402_15 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000008438 267.0
PYH1_k127_294402_16 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005457 241.0
PYH1_k127_294402_17 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000004659 195.0
PYH1_k127_294402_18 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000002525 169.0
PYH1_k127_294402_19 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000000000000003003 175.0
PYH1_k127_294402_2 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 595.0
PYH1_k127_294402_20 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000007147 160.0
PYH1_k127_294402_21 PFAM MaoC like domain - - - 0.00000000000000000000000506 118.0
PYH1_k127_294402_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 610.0
PYH1_k127_294402_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 554.0
PYH1_k127_294402_5 L-carnitine dehydratase bile acid-inducible protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 545.0
PYH1_k127_294402_6 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 471.0
PYH1_k127_294402_7 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 434.0
PYH1_k127_294402_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 380.0
PYH1_k127_294402_9 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
PYH1_k127_2944967_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 559.0
PYH1_k127_2944967_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 414.0
PYH1_k127_2944967_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 370.0
PYH1_k127_2944967_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 283.0
PYH1_k127_2944967_4 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001493 260.0
PYH1_k127_2944967_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000005222 133.0
PYH1_k127_2962453_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.4e-312 989.0
PYH1_k127_2962453_1 choline dehydrogenase activity - - - 2.98e-272 844.0
PYH1_k127_2962453_2 radical SAM domain protein K04034 - 1.21.98.3 1.929e-225 714.0
PYH1_k127_2962453_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 445.0
PYH1_k127_2962453_4 lipopolysaccharide transport K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 414.0
PYH1_k127_2962453_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 336.0
PYH1_k127_2962453_6 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 307.0
PYH1_k127_2962453_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002811 149.0
PYH1_k127_2962453_8 Putative zinc-finger - - - 0.00000001133 61.0
PYH1_k127_296491_0 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 406.0
PYH1_k127_296491_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 388.0
PYH1_k127_296491_2 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000006558 217.0
PYH1_k127_296491_3 SIS domain K07106 - 4.2.1.126 0.0000000000000000000000000000000000001721 146.0
PYH1_k127_296491_4 -acetyltransferase - - - 0.00000000000000000000000001915 115.0
PYH1_k127_296491_6 carboxylic acid catabolic process K01706 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008872,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0071704,GO:1901575 4.2.1.40 0.0009972 45.0
PYH1_k127_29655_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 553.0
PYH1_k127_29655_1 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 525.0
PYH1_k127_29655_2 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 381.0
PYH1_k127_29655_3 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 334.0
PYH1_k127_29655_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
PYH1_k127_29655_5 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000003148 240.0
PYH1_k127_29655_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000001439 216.0
PYH1_k127_29655_8 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000005317 99.0
PYH1_k127_29655_9 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K11707 - - 0.00002869 56.0
PYH1_k127_2968531_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 489.0
PYH1_k127_2968531_1 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 457.0
PYH1_k127_2968531_2 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 425.0
PYH1_k127_2968531_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 346.0
PYH1_k127_2968531_4 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000001388 184.0
PYH1_k127_2968531_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000000009447 96.0
PYH1_k127_2975891_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.683e-281 885.0
PYH1_k127_2975891_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000001559 179.0
PYH1_k127_2975891_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000001186 176.0
PYH1_k127_2975891_3 Isochorismatase family - - - 0.00000000000000000000000000000000000000003342 159.0
PYH1_k127_2975891_4 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000005804 115.0
PYH1_k127_2975891_6 Magnesium chelatase, subunit ChlI K07391 - - 0.000001943 49.0
PYH1_k127_2988251_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.147e-194 628.0
PYH1_k127_2988251_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 397.0
PYH1_k127_2988251_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000009296 119.0
PYH1_k127_2988251_11 Regulatory protein - - - 0.0000000000000000000000001772 111.0
PYH1_k127_2988251_12 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000004236 103.0
PYH1_k127_2988251_13 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000008093 90.0
PYH1_k127_2988251_14 Major facilitator Superfamily - - - 0.00007813 49.0
PYH1_k127_2988251_15 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0005102 43.0
PYH1_k127_2988251_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 396.0
PYH1_k127_2988251_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
PYH1_k127_2988251_4 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 350.0
PYH1_k127_2988251_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000004248 259.0
PYH1_k127_2988251_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000007633 263.0
PYH1_k127_2988251_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001434 246.0
PYH1_k127_2988251_8 Lysin motif K06194 - - 0.0000000000000000000000000000000000008427 151.0
PYH1_k127_2988251_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.000000000000000000000000000000004451 135.0
PYH1_k127_3008360_0 indolepyruvate ferredoxin oxidoreductase activity K00175,K04090 - 1.2.7.11,1.2.7.3,1.2.7.8 0.0 1301.0
PYH1_k127_3008360_1 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000001865 211.0
PYH1_k127_3008360_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000007513 180.0
PYH1_k127_3012832_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 509.0
PYH1_k127_3012832_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
PYH1_k127_3012832_2 Glycine-zipper domain - - - 0.00000001672 60.0
PYH1_k127_3014847_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 499.0
PYH1_k127_3014847_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 467.0
PYH1_k127_3014847_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000007048 267.0
PYH1_k127_3014847_3 oxidation-reduction process - - - 0.0000000000000000000000000000000000005125 144.0
PYH1_k127_3014939_0 Dehydrogenase - - - 6.795e-218 703.0
PYH1_k127_3014939_1 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 604.0
PYH1_k127_3014939_2 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 474.0
PYH1_k127_3014939_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 348.0
PYH1_k127_3014939_4 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000007737 96.0
PYH1_k127_3019323_0 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 335.0
PYH1_k127_3019323_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
PYH1_k127_3019323_2 - - - - 0.00000002362 63.0
PYH1_k127_3019323_3 YMGG-like Gly-zipper - - - 0.00000007661 55.0
PYH1_k127_3048337_0 dehydrogenase - - - 3.759e-206 663.0
PYH1_k127_3048337_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 559.0
PYH1_k127_3048337_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002986 248.0
PYH1_k127_3048337_3 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000003078 230.0
PYH1_k127_3048337_4 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.00000000000000000000000000000000000000000000000000000000001016 234.0
PYH1_k127_3048337_5 transferase activity, transferring glycosyl groups K20444 - - 0.0000000000000000000000000000000000000000000000000000000001205 219.0
PYH1_k127_3048337_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000003475 186.0
PYH1_k127_3048337_7 Oxidoreductase FAD-binding domain K16246 - - 0.0000000000000000000000004997 113.0
PYH1_k127_3048337_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000006313 62.0
PYH1_k127_3048337_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0003118 51.0
PYH1_k127_3054915_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.784e-200 634.0
PYH1_k127_3054915_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 323.0
PYH1_k127_3054915_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000005101 145.0
PYH1_k127_3054915_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000614 139.0
PYH1_k127_3054915_12 Ribosomal protein L30 K02907 - - 0.0000000000001 74.0
PYH1_k127_3054915_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000004386 66.0
PYH1_k127_3054915_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 268.0
PYH1_k127_3054915_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000001368 252.0
PYH1_k127_3054915_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000009254 211.0
PYH1_k127_3054915_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000002099 210.0
PYH1_k127_3054915_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000008721 195.0
PYH1_k127_3054915_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001244 191.0
PYH1_k127_3054915_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000002097 168.0
PYH1_k127_3054915_9 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001884 166.0
PYH1_k127_3068108_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 350.0
PYH1_k127_3068108_1 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
PYH1_k127_307175_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 484.0
PYH1_k127_307175_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 406.0
PYH1_k127_307175_10 - - - - 0.00000003521 64.0
PYH1_k127_307175_11 AsmA family K07289,K07290 - - 0.00000004133 66.0
PYH1_k127_307175_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 362.0
PYH1_k127_307175_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 344.0
PYH1_k127_307175_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002221 293.0
PYH1_k127_307175_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000943 276.0
PYH1_k127_307175_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000002903 185.0
PYH1_k127_307175_7 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000495 149.0
PYH1_k127_307175_8 Thioredoxin - - - 0.0000000000000000000000000000000007151 136.0
PYH1_k127_307175_9 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000007343 130.0
PYH1_k127_3084292_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 584.0
PYH1_k127_3084292_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000002486 213.0
PYH1_k127_3084292_2 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000001263 190.0
PYH1_k127_3086096_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000003378 228.0
PYH1_k127_3086096_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001696 218.0
PYH1_k127_3086096_2 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000001395 159.0
PYH1_k127_3101247_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 500.0
PYH1_k127_3101247_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 421.0
PYH1_k127_3101247_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 301.0
PYH1_k127_3101247_3 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000002809 233.0
PYH1_k127_3101247_4 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000003261 203.0
PYH1_k127_3101247_6 Luciferase-like monooxygenase K14728 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000004359 65.0
PYH1_k127_3101247_7 - - - - 0.000003302 53.0
PYH1_k127_310964_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 564.0
PYH1_k127_310964_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 447.0
PYH1_k127_310964_10 PFAM Tetratricopeptide repeat - - - 0.00000002267 61.0
PYH1_k127_310964_11 Transglutaminase-like superfamily - - - 0.00000005281 63.0
PYH1_k127_310964_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 440.0
PYH1_k127_310964_3 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 379.0
PYH1_k127_310964_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 316.0
PYH1_k127_310964_5 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000008375 227.0
PYH1_k127_310964_6 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.00000000000000000000000000000000000000000000002844 184.0
PYH1_k127_310964_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000002443 154.0
PYH1_k127_310964_8 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000001655 142.0
PYH1_k127_310964_9 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000009799 86.0
PYH1_k127_3189671_0 Peptidase family M1 domain K08776 - - 6.978e-226 728.0
PYH1_k127_3189671_1 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 609.0
PYH1_k127_3189671_10 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000006899 228.0
PYH1_k127_3189671_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000001152 228.0
PYH1_k127_3189671_12 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000004114 178.0
PYH1_k127_3189671_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000001088 166.0
PYH1_k127_3189671_14 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000001469 166.0
PYH1_k127_3189671_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000002721 140.0
PYH1_k127_3189671_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000865 136.0
PYH1_k127_3189671_17 Major Facilitator Superfamily - - - 0.00000000000000000000000000001771 132.0
PYH1_k127_3189671_18 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000001479 114.0
PYH1_k127_3189671_19 - - - - 0.0000000000000000000000004744 120.0
PYH1_k127_3189671_2 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 514.0
PYH1_k127_3189671_20 RNA recognition motif - - - 0.0000000000000000008274 89.0
PYH1_k127_3189671_21 Vitamin B12 dependent methionine synthase, activation domain - - - 0.00000000000000006743 89.0
PYH1_k127_3189671_22 CDGSH-type zinc finger. Function unknown. - - - 0.00000000001501 71.0
PYH1_k127_3189671_23 response regulator, receiver - - - 0.00002189 53.0
PYH1_k127_3189671_24 Major facilitator Superfamily - - - 0.000452 51.0
PYH1_k127_3189671_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 422.0
PYH1_k127_3189671_4 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 391.0
PYH1_k127_3189671_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 340.0
PYH1_k127_3189671_6 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 340.0
PYH1_k127_3189671_7 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000004036 256.0
PYH1_k127_3189671_8 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000004721 246.0
PYH1_k127_3189671_9 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000007408 241.0
PYH1_k127_3198608_0 cytochrome P450 K00493,K21257 - 1.14.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 395.0
PYH1_k127_3198608_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001427 267.0
PYH1_k127_3198608_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007544 237.0
PYH1_k127_3198608_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000005653 192.0
PYH1_k127_3198608_4 Major facilitator superfamily - - - 0.000000000000000000009176 102.0
PYH1_k127_3231671_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.285e-245 772.0
PYH1_k127_3231671_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
PYH1_k127_3231671_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000309 55.0
PYH1_k127_331693_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 408.0
PYH1_k127_331693_1 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 391.0
PYH1_k127_331693_10 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.00000000000000000000000000000008739 127.0
PYH1_k127_331693_11 6-pyruvoyl tetrahydropterin synthase QueD family protein - - - 0.00000000000000000000000001499 119.0
PYH1_k127_331693_12 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000175 100.0
PYH1_k127_331693_13 integral membrane protein - - - 0.000001531 56.0
PYH1_k127_331693_2 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 332.0
PYH1_k127_331693_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000344 274.0
PYH1_k127_331693_4 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
PYH1_k127_331693_5 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
PYH1_k127_331693_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000001459 211.0
PYH1_k127_331693_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000006498 187.0
PYH1_k127_331693_8 Phosphonate ABC transporter K02044 - - 0.000000000000000000000000000000000000000002456 169.0
PYH1_k127_331693_9 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000005383 145.0
PYH1_k127_3356316_0 Pfam:DUF1446 - - - 3.5e-222 702.0
PYH1_k127_3356316_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 447.0
PYH1_k127_3356316_10 - - - - 0.0000000000009054 71.0
PYH1_k127_3356316_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 337.0
PYH1_k127_3356316_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
PYH1_k127_3356316_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
PYH1_k127_3356316_5 Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
PYH1_k127_3356316_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003465 210.0
PYH1_k127_3356316_7 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000001017 172.0
PYH1_k127_3356316_8 Endoribonuclease L-PSP K09021 - - 0.00000000000000000000000000000000000006892 146.0
PYH1_k127_3359847_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 596.0
PYH1_k127_3359847_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 537.0
PYH1_k127_3359847_10 AhpC/TSA antioxidant enzyme - - - 0.00000000000000000000000000000001123 131.0
PYH1_k127_3359847_11 GYD domain - - - 0.0000000000000000001218 92.0
PYH1_k127_3359847_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0005692 43.0
PYH1_k127_3359847_2 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 368.0
PYH1_k127_3359847_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 344.0
PYH1_k127_3359847_4 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 293.0
PYH1_k127_3359847_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005035 284.0
PYH1_k127_3359847_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000108 249.0
PYH1_k127_3359847_7 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000000001356 224.0
PYH1_k127_3359847_8 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000004102 210.0
PYH1_k127_3359847_9 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000001778 154.0
PYH1_k127_3361874_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 559.0
PYH1_k127_3361874_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 333.0
PYH1_k127_3361874_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 315.0
PYH1_k127_3361874_3 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002534 247.0
PYH1_k127_3361874_4 NADPH:quinone reductase activity - - - 0.0000000000000000000000000000000000000000000000000000003126 200.0
PYH1_k127_3361874_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000002216 126.0
PYH1_k127_3361874_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000004725 98.0
PYH1_k127_3382769_0 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000002053 184.0
PYH1_k127_3382769_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000003726 168.0
PYH1_k127_3382769_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000002522 154.0
PYH1_k127_3382769_3 protein secretion K02460 - - 0.000000000000000000000000002377 127.0
PYH1_k127_3382769_4 PFAM Fimbrial assembly K02461 - - 0.000000000000000005418 97.0
PYH1_k127_3382769_5 general secretion pathway protein K02457 - - 0.0000000008135 66.0
PYH1_k127_3382769_6 Prokaryotic N-terminal methylation motif K02459 - - 0.0000003506 60.0
PYH1_k127_3382769_7 type IV pilus modification protein PilV K02458 - - 0.00002959 55.0
PYH1_k127_3410423_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 553.0
PYH1_k127_3410423_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 287.0
PYH1_k127_3410423_3 phosphorelay signal transduction system - - - 0.0000000006386 70.0
PYH1_k127_3415510_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.505e-268 841.0
PYH1_k127_3415510_1 Amidohydrolase family K01466 - 3.5.2.5 4.206e-214 688.0
PYH1_k127_3415510_10 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 408.0
PYH1_k127_3415510_11 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 333.0
PYH1_k127_3415510_12 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 312.0
PYH1_k127_3415510_13 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 314.0
PYH1_k127_3415510_14 Dihydropyrimidinase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 315.0
PYH1_k127_3415510_15 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 314.0
PYH1_k127_3415510_16 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 291.0
PYH1_k127_3415510_17 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 285.0
PYH1_k127_3415510_18 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002177 294.0
PYH1_k127_3415510_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002762 275.0
PYH1_k127_3415510_2 GMC oxidoreductase K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 542.0
PYH1_k127_3415510_20 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000276 276.0
PYH1_k127_3415510_21 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003146 269.0
PYH1_k127_3415510_22 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000006644 265.0
PYH1_k127_3415510_23 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002721 265.0
PYH1_k127_3415510_24 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000003188 214.0
PYH1_k127_3415510_25 PFAM binding-protein-dependent transport systems inner membrane component K15554 - - 0.000000000000000000000000000000000000000000000000000001361 205.0
PYH1_k127_3415510_26 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000003873 201.0
PYH1_k127_3415510_27 NMT1-like family - - - 0.0000000000000000000000000000000000000000000001191 189.0
PYH1_k127_3415510_28 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000009637 174.0
PYH1_k127_3415510_29 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000001077 173.0
PYH1_k127_3415510_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 516.0
PYH1_k127_3415510_30 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000005671 159.0
PYH1_k127_3415510_31 Involved in molybdopterin and thiamine biosynthesis, family 2 K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000001788 119.0
PYH1_k127_3415510_32 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000001141 121.0
PYH1_k127_3415510_33 Domain of unknown function (DUF4387) - - - 0.0000000000000000000000000009582 115.0
PYH1_k127_3415510_34 - - - - 0.000000000000000000000003564 109.0
PYH1_k127_3415510_35 DNA-sulfur modification-associated - - - 0.000000000000000006951 96.0
PYH1_k127_3415510_36 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000001217 91.0
PYH1_k127_3415510_37 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000002856 85.0
PYH1_k127_3415510_38 SnoaL-like domain - - - 0.000007211 52.0
PYH1_k127_3415510_4 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 500.0
PYH1_k127_3415510_5 Pfam:DUF1446 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 509.0
PYH1_k127_3415510_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 451.0
PYH1_k127_3415510_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 462.0
PYH1_k127_3415510_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 433.0
PYH1_k127_3415510_9 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 422.0
PYH1_k127_3415862_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 299.0
PYH1_k127_3415862_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000001014 233.0
PYH1_k127_3415862_2 Belongs to the GSP D family K02453 - - 0.0000000005577 70.0
PYH1_k127_3417395_0 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 559.0
PYH1_k127_3417395_1 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 503.0
PYH1_k127_3417395_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 354.0
PYH1_k127_3417395_3 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000004569 214.0
PYH1_k127_3417395_4 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000001979 141.0
PYH1_k127_3417395_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000002235 119.0
PYH1_k127_3417395_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.000000000000000003785 96.0
PYH1_k127_3421202_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.2e-218 698.0
PYH1_k127_3421202_1 AMP-binding enzyme K01897 - 6.2.1.3 1.034e-207 663.0
PYH1_k127_3421202_10 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 370.0
PYH1_k127_3421202_11 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
PYH1_k127_3421202_12 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 276.0
PYH1_k127_3421202_13 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000002912 233.0
PYH1_k127_3421202_14 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000001378 189.0
PYH1_k127_3421202_15 Enoyl-CoA hydratase K16425 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 - 0.0000000000000000000000000000000000000000009126 167.0
PYH1_k127_3421202_16 PFAM histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000001968 147.0
PYH1_k127_3421202_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000002764 62.0
PYH1_k127_3421202_18 UTRA K03710 - - 0.0000402 49.0
PYH1_k127_3421202_2 Periplasmic binding protein domain K01999 - - 3.347e-195 616.0
PYH1_k127_3421202_3 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
PYH1_k127_3421202_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 475.0
PYH1_k127_3421202_5 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 473.0
PYH1_k127_3421202_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 440.0
PYH1_k127_3421202_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 424.0
PYH1_k127_3421202_8 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 394.0
PYH1_k127_3421202_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 374.0
PYH1_k127_342429_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 548.0
PYH1_k127_342429_1 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001549 276.0
PYH1_k127_342429_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
PYH1_k127_342429_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000003009 185.0
PYH1_k127_342429_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000003945 137.0
PYH1_k127_342429_5 Tetratricopeptide repeat - - - 0.000000000001371 76.0
PYH1_k127_342429_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00001207 49.0
PYH1_k127_3433484_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.244e-201 637.0
PYH1_k127_3433484_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 471.0
PYH1_k127_3433484_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 411.0
PYH1_k127_3433484_3 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000006899 188.0
PYH1_k127_3433484_4 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000009269 165.0
PYH1_k127_3435413_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 488.0
PYH1_k127_3435413_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 490.0
PYH1_k127_3435413_2 PFAM Na Picotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 377.0
PYH1_k127_3435413_3 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 375.0
PYH1_k127_3435413_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
PYH1_k127_3435413_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000003924 181.0
PYH1_k127_3435413_6 phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000003572 119.0
PYH1_k127_3474087_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1032.0
PYH1_k127_3474087_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 425.0
PYH1_k127_3474087_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 285.0
PYH1_k127_3474087_3 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000002161 190.0
PYH1_k127_3474087_4 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000000000000007845 123.0
PYH1_k127_3474087_5 - - - - 0.000000000000000000000002488 118.0
PYH1_k127_3474087_6 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000003626 76.0
PYH1_k127_3474087_7 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000004206 58.0
PYH1_k127_3479347_0 PFAM MgsA AAA ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 499.0
PYH1_k127_3479347_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 391.0
PYH1_k127_3479347_10 Maf-like protein K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000000000000000000000000000452 176.0
PYH1_k127_3479347_11 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000004998 156.0
PYH1_k127_3479347_12 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000004351 149.0
PYH1_k127_3479347_13 Methyltransferase domain - - - 0.0000000000000000000000000003594 127.0
PYH1_k127_3479347_14 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000005819 98.0
PYH1_k127_3479347_15 ABC-type nitrate sulfonate bicarbonate transport - - - 0.000000008719 67.0
PYH1_k127_3479347_16 Tetratricopeptide repeat - - - 0.00000003141 64.0
PYH1_k127_3479347_2 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 354.0
PYH1_k127_3479347_3 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 335.0
PYH1_k127_3479347_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 331.0
PYH1_k127_3479347_5 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 313.0
PYH1_k127_3479347_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 296.0
PYH1_k127_3479347_7 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
PYH1_k127_3479347_8 regulatory protein, gntR - - - 0.000000000000000000000000000000000000000000000000000000000000000008046 237.0
PYH1_k127_3479347_9 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000001048 220.0
PYH1_k127_3479645_0 Domain of unknown function (DUF4861) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 365.0
PYH1_k127_3479645_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 342.0
PYH1_k127_3479645_10 transcriptional regulator, AbrB - - - 0.000000000007597 67.0
PYH1_k127_3479645_11 - - - - 0.0000007588 51.0
PYH1_k127_3479645_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 340.0
PYH1_k127_3479645_3 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 329.0
PYH1_k127_3479645_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002561 293.0
PYH1_k127_3479645_5 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009679 289.0
PYH1_k127_3479645_6 P-loop containing region of AAA domain K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001644 287.0
PYH1_k127_3479645_7 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000002222 213.0
PYH1_k127_3479645_8 - - - - 0.00000000000000000000000000000000000000000009627 179.0
PYH1_k127_3479645_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000006691 110.0
PYH1_k127_3482623_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1324.0
PYH1_k127_3482623_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 562.0
PYH1_k127_3482623_2 sulfur oxidation protein soxY K17226 - - 0.0000000000000000004936 93.0
PYH1_k127_3482623_3 oxidation protein SoxZ K17227 - - 0.0005457 50.0
PYH1_k127_3505023_0 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006986 267.0
PYH1_k127_3505023_1 Protein of unknown function (DUF2652) - - - 0.000000000000000000000000000000000000000000000000000001322 205.0
PYH1_k127_3505023_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000001259 188.0
PYH1_k127_3505023_3 GAF domain - - - 0.000000000000000000000000000000000000002364 149.0
PYH1_k127_3505023_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000699 141.0
PYH1_k127_3505023_5 Membrane - - - 0.0000000000002703 78.0
PYH1_k127_3505023_6 hydrolase activity, acting on ester bonds - - - 0.0000000000003203 74.0
PYH1_k127_3505023_7 Transposase and inactivated derivatives - - - 0.000000002189 68.0
PYH1_k127_3516155_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 502.0
PYH1_k127_3516155_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 383.0
PYH1_k127_3516155_10 - - - - 0.000000000000000000002371 99.0
PYH1_k127_3516155_11 Protein of unknown function (DUF2442) - - - 0.000000003148 62.0
PYH1_k127_3516155_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 349.0
PYH1_k127_3516155_3 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 335.0
PYH1_k127_3516155_4 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000001578 227.0
PYH1_k127_3516155_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000001563 192.0
PYH1_k127_3516155_6 membrane K08978 - - 0.000000000000000000000000000000000000000000000001021 183.0
PYH1_k127_3516155_7 - - - - 0.0000000000000000000000000000000000000000002515 167.0
PYH1_k127_3516155_8 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000001094 160.0
PYH1_k127_3516155_9 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000004659 115.0
PYH1_k127_3529942_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
PYH1_k127_3529942_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000415 212.0
PYH1_k127_3529942_2 ribonucleoside-diphosphate reductase activity K07735 - - 0.00000000000000000000000000000000000000000000000002489 197.0
PYH1_k127_3532636_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1093.0
PYH1_k127_3532636_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 508.0
PYH1_k127_3532636_2 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000009225 183.0
PYH1_k127_3532636_3 FixH - - - 0.00000000000000000000002977 107.0
PYH1_k127_3532636_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000001167 90.0
PYH1_k127_3532636_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000001389 71.0
PYH1_k127_3532636_6 Universal stress protein - - - 0.000007411 49.0
PYH1_k127_3532636_7 - K07112 - - 0.00001271 48.0
PYH1_k127_3542810_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 355.0
PYH1_k127_3542810_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 314.0
PYH1_k127_3542810_10 CopC domain - - - 0.000000000000001183 81.0
PYH1_k127_3542810_11 - - - - 0.00002835 50.0
PYH1_k127_3542810_12 - - - - 0.0001728 51.0
PYH1_k127_3542810_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 307.0
PYH1_k127_3542810_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 290.0
PYH1_k127_3542810_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000235 293.0
PYH1_k127_3542810_5 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000003395 208.0
PYH1_k127_3542810_6 Formate hydrogenlyase K12136,K15827 - - 0.0000000000000000000000000000000000000000000000000003072 188.0
PYH1_k127_3542810_7 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000008072 185.0
PYH1_k127_3542810_8 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.0000000000000000000000000000000000000000000009787 172.0
PYH1_k127_3542810_9 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000003033 142.0
PYH1_k127_3577929_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1475.0
PYH1_k127_3577929_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 516.0
PYH1_k127_3577929_10 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000001988 189.0
PYH1_k127_3577929_11 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000002126 175.0
PYH1_k127_3577929_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 514.0
PYH1_k127_3577929_3 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 414.0
PYH1_k127_3577929_4 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
PYH1_k127_3577929_5 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 374.0
PYH1_k127_3577929_6 PFAM amidohydrolase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000413 280.0
PYH1_k127_3577929_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
PYH1_k127_3577929_8 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000005909 247.0
PYH1_k127_3577929_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000006662 232.0
PYH1_k127_3580388_0 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 1.277e-208 657.0
PYH1_k127_3580388_1 PFAM amidohydrolase K07045 - - 4.383e-196 626.0
PYH1_k127_3580388_10 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000106 180.0
PYH1_k127_3580388_11 ABC transporter K02049 - - 0.0000000000000000000000000000000001087 139.0
PYH1_k127_3580388_12 Mannose-6-phosphate isomerase - - - 0.000000001735 65.0
PYH1_k127_3580388_2 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 587.0
PYH1_k127_3580388_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 369.0
PYH1_k127_3580388_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 324.0
PYH1_k127_3580388_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 322.0
PYH1_k127_3580388_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 299.0
PYH1_k127_3580388_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006477 277.0
PYH1_k127_3580388_8 3-isopropylmalate dehydrogenase activity K00052,K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85,1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000001294 282.0
PYH1_k127_3580388_9 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000003385 245.0
PYH1_k127_3589536_0 histidine kinase, HAMP K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 563.0
PYH1_k127_3589536_1 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 526.0
PYH1_k127_3589536_2 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 405.0
PYH1_k127_3589536_3 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001975 288.0
PYH1_k127_3589536_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000002568 258.0
PYH1_k127_3589536_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000003336 242.0
PYH1_k127_3589536_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000004301 175.0
PYH1_k127_3589536_7 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000541 157.0
PYH1_k127_3589536_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000001526 142.0
PYH1_k127_3589536_9 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000001007 62.0
PYH1_k127_3602913_0 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 364.0
PYH1_k127_3602913_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
PYH1_k127_3602913_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001179 224.0
PYH1_k127_3602913_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000001961 134.0
PYH1_k127_3602913_4 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000001261 95.0
PYH1_k127_3615617_0 DNA helicase K03654 - 3.6.4.12 3.698e-208 666.0
PYH1_k127_3615617_1 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 394.0
PYH1_k127_3615617_2 PFAM extracellular solute-binding protein family 1 K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
PYH1_k127_3615617_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000003883 226.0
PYH1_k127_3685191_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 492.0
PYH1_k127_3685191_1 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 488.0
PYH1_k127_3685191_2 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 347.0
PYH1_k127_3685191_3 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 332.0
PYH1_k127_3685191_4 amidase activity - - - 0.0000000000000000000000000000000000000000000000000000002239 198.0
PYH1_k127_3685191_5 Thioesterase superfamily - - - 0.000000000000000000000000000002848 137.0
PYH1_k127_3685191_6 endonuclease activity - - - 0.000000004731 65.0
PYH1_k127_3685191_7 endonuclease activity - - - 0.00000000761 63.0
PYH1_k127_3779227_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1606.0
PYH1_k127_3779227_1 Lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000001421 207.0
PYH1_k127_3779227_2 YacP-like NYN domain K06962 - - 0.000000000000001191 83.0
PYH1_k127_3804194_0 PFAM Mannosyl oligosaccharide glucosidase - - - 1.187e-307 955.0
PYH1_k127_3804194_1 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 513.0
PYH1_k127_3804194_10 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000001731 111.0
PYH1_k127_3804194_11 - - - - 0.000001012 54.0
PYH1_k127_3804194_12 OsmC-like protein - - - 0.000001894 53.0
PYH1_k127_3804194_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 371.0
PYH1_k127_3804194_3 belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 340.0
PYH1_k127_3804194_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 326.0
PYH1_k127_3804194_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 294.0
PYH1_k127_3804194_6 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004546 273.0
PYH1_k127_3804194_7 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000008012 153.0
PYH1_k127_3804194_8 DoxX K15977 - - 0.0000000000000000000000000000000000001486 148.0
PYH1_k127_3804194_9 - - - - 0.000000000000000000000000002073 116.0
PYH1_k127_3805110_0 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249,K18244 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 556.0
PYH1_k127_3805110_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 387.0
PYH1_k127_3805110_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002291 271.0
PYH1_k127_3805110_3 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000004857 239.0
PYH1_k127_3805110_4 membrane - - - 0.000000000000000000000000000000000001446 160.0
PYH1_k127_3805110_5 Protein of unknown function (DUF3752) - - - 0.000000000000000000008425 105.0
PYH1_k127_3805110_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000005621 78.0
PYH1_k127_3805110_7 intermembrane phospholipid transfer K07323 - - 0.00000003408 57.0
PYH1_k127_3805110_8 - - - - 0.00000004988 54.0
PYH1_k127_3805110_9 cellulose binding K00505,K01406 - 1.14.18.1,3.4.24.40 0.00003361 54.0
PYH1_k127_3824347_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 423.0
PYH1_k127_3824347_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000008844 92.0
PYH1_k127_3864311_0 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 537.0
PYH1_k127_3864311_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 494.0
PYH1_k127_3864311_10 TPM domain - - - 0.0000000000000000000000000000001321 133.0
PYH1_k127_3864311_11 Protein of unknown function (DUF1624) - - - 0.00000000329 69.0
PYH1_k127_3864311_12 Transposase - - - 0.00000114 54.0
PYH1_k127_3864311_2 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 461.0
PYH1_k127_3864311_3 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 403.0
PYH1_k127_3864311_4 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 330.0
PYH1_k127_3864311_5 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 319.0
PYH1_k127_3864311_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000002897 228.0
PYH1_k127_3864311_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004654 228.0
PYH1_k127_3864311_8 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000009422 172.0
PYH1_k127_3864311_9 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000702 155.0
PYH1_k127_3886675_0 PFAM FAD linked oxidase domain protein - - - 2.812e-304 963.0
PYH1_k127_3886675_1 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 1.338e-231 735.0
PYH1_k127_3886675_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000003721 83.0
PYH1_k127_3957396_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.429e-215 716.0
PYH1_k127_3957396_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 597.0
PYH1_k127_3957396_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 349.0
PYH1_k127_3957396_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000001511 278.0
PYH1_k127_3957396_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000001412 201.0
PYH1_k127_3957396_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000001841 186.0
PYH1_k127_3964460_0 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 386.0
PYH1_k127_3964460_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 304.0
PYH1_k127_3964460_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 276.0
PYH1_k127_3964460_3 DivIVA protein K04074 - - 0.00000000000000000000006497 104.0
PYH1_k127_3964460_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000001047 93.0
PYH1_k127_3964460_5 YGGT family K02221 - - 0.000000000000001579 87.0
PYH1_k127_3964460_6 DUF167 - - - 0.00000000000008224 77.0
PYH1_k127_4004709_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.031e-278 872.0
PYH1_k127_4004709_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 581.0
PYH1_k127_4004709_10 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 400.0
PYH1_k127_4004709_11 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 346.0
PYH1_k127_4004709_12 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000005734 168.0
PYH1_k127_4004709_13 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000004483 147.0
PYH1_k127_4004709_14 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000007571 130.0
PYH1_k127_4004709_15 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000002261 132.0
PYH1_k127_4004709_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 535.0
PYH1_k127_4004709_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 498.0
PYH1_k127_4004709_4 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 475.0
PYH1_k127_4004709_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 440.0
PYH1_k127_4004709_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 438.0
PYH1_k127_4004709_7 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 436.0
PYH1_k127_4004709_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 398.0
PYH1_k127_4004709_9 Branched-chain amino acid transport K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 391.0
PYH1_k127_4008857_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 1.913e-310 981.0
PYH1_k127_4008857_1 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 380.0
PYH1_k127_4008857_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000001172 254.0
PYH1_k127_4008857_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000005849 67.0
PYH1_k127_4015681_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.103e-247 773.0
PYH1_k127_4015681_1 amino acid - - - 6.124e-211 673.0
PYH1_k127_4015681_10 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000001485 86.0
PYH1_k127_4015681_11 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000005325 70.0
PYH1_k127_4015681_2 Amino acid permease - - - 1.103e-206 659.0
PYH1_k127_4015681_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 494.0
PYH1_k127_4015681_4 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000003297 195.0
PYH1_k127_4015681_5 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000704 160.0
PYH1_k127_4015681_6 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000007149 151.0
PYH1_k127_4015681_7 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000002604 139.0
PYH1_k127_4015681_8 PFAM SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.00000000000000000000000001362 123.0
PYH1_k127_4015681_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000001102 96.0
PYH1_k127_4029407_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1089.0
PYH1_k127_4029407_1 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007715 254.0
PYH1_k127_4029407_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005031 242.0
PYH1_k127_4029407_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
PYH1_k127_4029407_4 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000002691 206.0
PYH1_k127_4029407_5 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000001453 194.0
PYH1_k127_4029407_6 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000001218 149.0
PYH1_k127_414360_0 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
PYH1_k127_414360_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001491 257.0
PYH1_k127_414360_2 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000005414 242.0
PYH1_k127_414360_3 PFAM Copper resistance D K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000001387 230.0
PYH1_k127_414360_4 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000007547 213.0
PYH1_k127_414360_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K00363,K05710,K17247 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000798 199.0
PYH1_k127_414360_6 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000001215 129.0
PYH1_k127_414360_7 phosphatidate phosphatase activity - - - 0.000000000003654 74.0
PYH1_k127_414360_8 Copper binding periplasmic protein CusF - - - 0.0002257 53.0
PYH1_k127_4144117_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 539.0
PYH1_k127_4144117_1 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 509.0
PYH1_k127_4144117_10 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000009801 183.0
PYH1_k127_4144117_11 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000003891 154.0
PYH1_k127_4144117_12 Tetratricopeptide repeat - - - 0.0002563 52.0
PYH1_k127_4144117_2 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 474.0
PYH1_k127_4144117_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 412.0
PYH1_k127_4144117_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 378.0
PYH1_k127_4144117_5 PFAM type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000332 294.0
PYH1_k127_4144117_6 SMART ATPase, AAA type, core K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002111 278.0
PYH1_k127_4144117_7 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000002929 242.0
PYH1_k127_4144117_8 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000003591 191.0
PYH1_k127_4144117_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000001562 186.0
PYH1_k127_4147586_0 Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 516.0
PYH1_k127_4147586_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 445.0
PYH1_k127_4147586_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 346.0
PYH1_k127_4147586_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 317.0
PYH1_k127_4147586_4 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
PYH1_k127_4147586_5 Sigma-70 region 2 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000006803 145.0
PYH1_k127_4147586_6 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000003672 138.0
PYH1_k127_4147586_7 O-Antigen ligase K18814 - - 0.000000000000000000001712 108.0
PYH1_k127_4147586_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000001721 102.0
PYH1_k127_4147586_9 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.0000005732 51.0
PYH1_k127_4163016_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 494.0
PYH1_k127_4163016_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 433.0
PYH1_k127_4163016_2 Histidine kinase K01991,K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 390.0
PYH1_k127_4163016_3 L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 361.0
PYH1_k127_4163016_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 340.0
PYH1_k127_4163016_5 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 334.0
PYH1_k127_4163016_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 310.0
PYH1_k127_4163016_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000007228 239.0
PYH1_k127_4163016_8 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000004292 216.0
PYH1_k127_4163016_9 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000003794 74.0
PYH1_k127_41636_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 489.0
PYH1_k127_41636_1 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000000000001249 131.0
PYH1_k127_41636_2 - - - - 0.0002177 44.0
PYH1_k127_4197485_0 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 535.0
PYH1_k127_4197485_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 293.0
PYH1_k127_4197485_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000002538 132.0
PYH1_k127_4197485_3 Cytochrome c K00406 - - 0.000000001559 64.0
PYH1_k127_4210415_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.328e-262 847.0
PYH1_k127_4210415_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002999 276.0
PYH1_k127_4210415_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000003946 248.0
PYH1_k127_4210415_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000002009 206.0
PYH1_k127_4210415_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000001231 139.0
PYH1_k127_4210415_5 Belongs to the ompA family K03640 - - 0.0000000000000000005468 95.0
PYH1_k127_4210415_6 pyridoxamine 5-phosphate K07005 - - 0.00000000000001891 81.0
PYH1_k127_4242461_0 Belongs to the ClpA ClpB family K03696 - - 5e-324 1009.0
PYH1_k127_4242461_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 573.0
PYH1_k127_4242461_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000002298 247.0
PYH1_k127_4242461_11 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000005634 248.0
PYH1_k127_4242461_12 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000003453 236.0
PYH1_k127_4242461_13 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000002539 228.0
PYH1_k127_4242461_14 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000000004315 171.0
PYH1_k127_4242461_15 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000000000000000005836 180.0
PYH1_k127_4242461_16 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000001042 155.0
PYH1_k127_4242461_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000001318 108.0
PYH1_k127_4242461_18 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000001871 106.0
PYH1_k127_4242461_2 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 486.0
PYH1_k127_4242461_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 411.0
PYH1_k127_4242461_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 351.0
PYH1_k127_4242461_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 347.0
PYH1_k127_4242461_6 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 340.0
PYH1_k127_4242461_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 307.0
PYH1_k127_4242461_8 inositol 2-dehydrogenase activity K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 299.0
PYH1_k127_4242461_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 300.0
PYH1_k127_4268084_0 B12 binding domain K00548 - 2.1.1.13 0.0 1421.0
PYH1_k127_4268084_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 456.0
PYH1_k127_4268084_10 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002592 252.0
PYH1_k127_4268084_11 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000003777 231.0
PYH1_k127_4268084_12 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005729 225.0
PYH1_k127_4268084_13 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000001956 214.0
PYH1_k127_4268084_14 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000027 209.0
PYH1_k127_4268084_15 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000008628 194.0
PYH1_k127_4268084_16 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000002724 181.0
PYH1_k127_4268084_18 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000005305 154.0
PYH1_k127_4268084_19 phosphorelay signal transduction system K11443 - - 0.000000000000000000000000000000000002604 156.0
PYH1_k127_4268084_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 464.0
PYH1_k127_4268084_20 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000005012 145.0
PYH1_k127_4268084_21 3-carboxyethylcatechol 2,3-dioxygenase activity K05713 - 1.13.11.16 0.0000000000000000000000000000000007714 143.0
PYH1_k127_4268084_22 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000266 142.0
PYH1_k127_4268084_23 transferase activity, transferring acyl groups K03824,K15520 - 2.3.1.189 0.00000000000000000000000003137 123.0
PYH1_k127_4268084_24 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000000001894 119.0
PYH1_k127_4268084_25 Desulfoferrodoxin K05919 - 1.15.1.2 0.00000000000000003135 90.0
PYH1_k127_4268084_26 - - - - 0.000004978 53.0
PYH1_k127_4268084_27 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000885 46.0
PYH1_k127_4268084_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 433.0
PYH1_k127_4268084_4 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 336.0
PYH1_k127_4268084_5 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 327.0
PYH1_k127_4268084_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 310.0
PYH1_k127_4268084_7 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 306.0
PYH1_k127_4268084_8 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008743 267.0
PYH1_k127_4268084_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000009221 256.0
PYH1_k127_4274264_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 562.0
PYH1_k127_4274264_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 531.0
PYH1_k127_4274264_10 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000003586 145.0
PYH1_k127_4274264_11 NIPSNAP - - - 0.000000000000000000000000000000009527 130.0
PYH1_k127_4274264_12 Histidine kinase - - - 0.0000000000000000000001255 103.0
PYH1_k127_4274264_13 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000003973 78.0
PYH1_k127_4274264_14 Helix-turn-helix domain - - - 0.00001448 49.0
PYH1_k127_4274264_2 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 378.0
PYH1_k127_4274264_3 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 375.0
PYH1_k127_4274264_4 hydrolase of alkaline phosphatase superfamily K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 361.0
PYH1_k127_4274264_5 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 345.0
PYH1_k127_4274264_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 346.0
PYH1_k127_4274264_7 hydrolase of alkaline phosphatase superfamily K07014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 348.0
PYH1_k127_4274264_8 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
PYH1_k127_4274264_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002785 223.0
PYH1_k127_4279292_0 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 501.0
PYH1_k127_4279292_1 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 411.0
PYH1_k127_4279292_2 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000000000000000000000000000001836 133.0
PYH1_k127_4279292_3 PHP family - - - 0.000000000000003721 83.0
PYH1_k127_4279292_4 Belongs to the ompA family - - - 0.00000000000007166 81.0
PYH1_k127_4279292_5 - - - - 0.00000001255 62.0
PYH1_k127_4279292_6 PFAM GGDEF domain containing protein - - - 0.00000007933 60.0
PYH1_k127_434214_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.365e-241 763.0
PYH1_k127_434214_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.386e-225 737.0
PYH1_k127_434214_10 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 404.0
PYH1_k127_434214_11 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
PYH1_k127_434214_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 388.0
PYH1_k127_434214_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 371.0
PYH1_k127_434214_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 379.0
PYH1_k127_434214_15 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 337.0
PYH1_k127_434214_16 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 335.0
PYH1_k127_434214_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007205 278.0
PYH1_k127_434214_18 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000007404 266.0
PYH1_k127_434214_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
PYH1_k127_434214_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 589.0
PYH1_k127_434214_20 NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000002878 157.0
PYH1_k127_434214_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000004891 156.0
PYH1_k127_434214_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000001251 160.0
PYH1_k127_434214_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000001876 128.0
PYH1_k127_434214_24 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000001984 112.0
PYH1_k127_434214_25 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000005855 86.0
PYH1_k127_434214_26 Phosphoribosyl transferase domain - - - 0.00000000000000006875 82.0
PYH1_k127_434214_27 YtxH-like protein - - - 0.000000001675 63.0
PYH1_k127_434214_28 cAMP biosynthetic process K03765 - - 0.000001341 60.0
PYH1_k127_434214_29 Evidence 5 No homology to any previously reported sequences K03765 - - 0.000001836 58.0
PYH1_k127_434214_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 480.0
PYH1_k127_434214_4 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 460.0
PYH1_k127_434214_5 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 456.0
PYH1_k127_434214_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 451.0
PYH1_k127_434214_7 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 440.0
PYH1_k127_434214_8 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 433.0
PYH1_k127_434214_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 424.0
PYH1_k127_4359703_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 4.622e-217 695.0
PYH1_k127_4359703_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 398.0
PYH1_k127_4359703_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 304.0
PYH1_k127_4359703_3 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000002744 222.0
PYH1_k127_4359703_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000004465 201.0
PYH1_k127_4362148_0 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 608.0
PYH1_k127_4362148_1 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 527.0
PYH1_k127_4362148_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002217 173.0
PYH1_k127_4362148_11 Arginine repressor, DNA binding domain K03402 - - 0.000000000000000000002162 100.0
PYH1_k127_4362148_12 - - - - 0.00000000000002106 85.0
PYH1_k127_4362148_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 498.0
PYH1_k127_4362148_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 437.0
PYH1_k127_4362148_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 371.0
PYH1_k127_4362148_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 313.0
PYH1_k127_4362148_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006593 269.0
PYH1_k127_4362148_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000122 254.0
PYH1_k127_4362148_8 of the double-stranded beta helix - - - 0.0000000000000000000000000000000000000000000000000000000000000004771 224.0
PYH1_k127_4362148_9 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001553 177.0
PYH1_k127_4381045_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 3e-323 1015.0
PYH1_k127_4381045_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 379.0
PYH1_k127_4381045_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 375.0
PYH1_k127_4381045_3 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 345.0
PYH1_k127_4381045_4 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 341.0
PYH1_k127_4381045_5 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 315.0
PYH1_k127_4381045_6 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002711 227.0
PYH1_k127_4381045_7 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000596 166.0
PYH1_k127_4381045_8 Helix-turn-helix - - - 0.0000000000000002666 90.0
PYH1_k127_4394055_0 PFAM Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 557.0
PYH1_k127_4394055_1 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 381.0
PYH1_k127_4394055_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005635 255.0
PYH1_k127_4394055_3 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001552 247.0
PYH1_k127_4394055_4 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000002758 198.0
PYH1_k127_4394055_5 Putative cyclase - - - 0.000000000000000000000000000000000000000000000003395 186.0
PYH1_k127_4396438_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 501.0
PYH1_k127_4396438_1 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 428.0
PYH1_k127_4396438_10 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000269 192.0
PYH1_k127_4396438_11 membrane - - - 0.00000000000000000000000000000000000000000001911 165.0
PYH1_k127_4396438_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000001013 165.0
PYH1_k127_4396438_14 ABC transporter substrate binding protein K01989 - - 0.0003061 43.0
PYH1_k127_4396438_2 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 398.0
PYH1_k127_4396438_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 374.0
PYH1_k127_4396438_4 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 346.0
PYH1_k127_4396438_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008277 258.0
PYH1_k127_4396438_6 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000003172 229.0
PYH1_k127_4396438_7 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000004014 242.0
PYH1_k127_4396438_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000001948 191.0
PYH1_k127_4396438_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000003813 186.0
PYH1_k127_4401285_0 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 471.0
PYH1_k127_4401285_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 475.0
PYH1_k127_4401285_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000001059 192.0
PYH1_k127_4401285_11 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000149 152.0
PYH1_k127_4401285_2 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 467.0
PYH1_k127_4401285_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 416.0
PYH1_k127_4401285_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 367.0
PYH1_k127_4401285_5 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 365.0
PYH1_k127_4401285_6 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001498 254.0
PYH1_k127_4401285_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001769 259.0
PYH1_k127_4401285_8 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
PYH1_k127_4401285_9 NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000001434 229.0
PYH1_k127_4424819_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 511.0
PYH1_k127_4424819_1 PFAM Short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 374.0
PYH1_k127_4479018_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.344e-291 911.0
PYH1_k127_4479018_1 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 1.145e-236 747.0
PYH1_k127_4479018_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000002168 127.0
PYH1_k127_4479018_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 591.0
PYH1_k127_4479018_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 574.0
PYH1_k127_4479018_4 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K02438 - 3.2.1.196,3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 550.0
PYH1_k127_4479018_5 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
PYH1_k127_4479018_6 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 298.0
PYH1_k127_4479018_7 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 292.0
PYH1_k127_4479018_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000004087 218.0
PYH1_k127_4479018_9 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000603 186.0
PYH1_k127_4486263_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 369.0
PYH1_k127_4486263_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000357 184.0
PYH1_k127_4486263_2 Surface antigen - - - 0.00002731 51.0
PYH1_k127_4528554_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 1.686e-199 629.0
PYH1_k127_4528554_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 606.0
PYH1_k127_4528554_11 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000008857 217.0
PYH1_k127_4528554_12 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000001133 159.0
PYH1_k127_4528554_13 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000002522 164.0
PYH1_k127_4528554_14 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000004469 118.0
PYH1_k127_4528554_15 - - - - 0.00000000000000000000003835 107.0
PYH1_k127_4528554_16 InterPro IPR007367 - - - 0.000000000000000000005792 102.0
PYH1_k127_4528554_17 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000001092 104.0
PYH1_k127_4528554_18 Cupin 2, conserved barrel domain protein - - - 0.000000000000000004738 91.0
PYH1_k127_4528554_19 Redoxin K03564 - 1.11.1.15 0.00000000001071 69.0
PYH1_k127_4528554_2 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 565.0
PYH1_k127_4528554_20 - - - - 0.000000008418 64.0
PYH1_k127_4528554_21 Redoxin K03386 - 1.11.1.15 0.000001171 51.0
PYH1_k127_4528554_22 - - - - 0.0001718 51.0
PYH1_k127_4528554_23 Transposase - - - 0.0007587 49.0
PYH1_k127_4528554_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 499.0
PYH1_k127_4528554_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 368.0
PYH1_k127_4528554_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 356.0
PYH1_k127_4528554_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 346.0
PYH1_k127_4528554_7 Belongs to the amidase family K01426,K19795 - 3.5.1.4,3.5.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 304.0
PYH1_k127_4528554_8 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
PYH1_k127_4528554_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 270.0
PYH1_k127_45473_0 Protein conserved in bacteria K06320 - - 0.00000000000000000000000000000000032 145.0
PYH1_k127_45473_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000002682 125.0
PYH1_k127_4568819_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 594.0
PYH1_k127_4568819_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 501.0
PYH1_k127_4568819_10 TIGRFAM MoaD family protein K03636 - - 0.0000000000000000000000000000000003502 133.0
PYH1_k127_4568819_11 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000009915 133.0
PYH1_k127_4568819_12 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000003833 118.0
PYH1_k127_4568819_13 NIL - - - 0.0000000000000005843 85.0
PYH1_k127_4568819_14 endonuclease activity - - - 0.000000000000008505 77.0
PYH1_k127_4568819_15 Domain of unknown function (DUF4349) - - - 0.00000002691 66.0
PYH1_k127_4568819_2 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 481.0
PYH1_k127_4568819_3 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 423.0
PYH1_k127_4568819_4 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 422.0
PYH1_k127_4568819_5 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 349.0
PYH1_k127_4568819_6 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
PYH1_k127_4568819_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000343 296.0
PYH1_k127_4568819_8 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007645 274.0
PYH1_k127_4568819_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000001077 155.0
PYH1_k127_4577333_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000006918 187.0
PYH1_k127_4577333_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000001351 180.0
PYH1_k127_4577333_2 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000006614 125.0
PYH1_k127_4577333_3 PAS PAC sensor hybrid histidine kinase - - - 0.000000000000000000000006821 107.0
PYH1_k127_4594667_0 PFAM Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 572.0
PYH1_k127_4594667_1 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 507.0
PYH1_k127_4594667_10 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000003997 206.0
PYH1_k127_4594667_11 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000001004 187.0
PYH1_k127_4594667_12 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000009864 150.0
PYH1_k127_4594667_13 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000009531 142.0
PYH1_k127_4594667_14 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000005997 139.0
PYH1_k127_4594667_15 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000002523 138.0
PYH1_k127_4594667_16 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000001847 136.0
PYH1_k127_4594667_17 hydroperoxide reductase activity - - - 0.000000000000000000000000000006602 128.0
PYH1_k127_4594667_18 Pkd domain containing protein - - - 0.00000000000000000000000000002241 129.0
PYH1_k127_4594667_19 Rhodanese Homology Domain - - - 0.00000000000000000000000002472 113.0
PYH1_k127_4594667_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 407.0
PYH1_k127_4594667_20 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000001825 102.0
PYH1_k127_4594667_21 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000001287 103.0
PYH1_k127_4594667_22 Aminotransferase class I and II - - - 0.0000000000000003218 88.0
PYH1_k127_4594667_23 STAS domain K04749 - - 0.000000000000001323 80.0
PYH1_k127_4594667_24 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.000000001609 68.0
PYH1_k127_4594667_25 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0000007907 61.0
PYH1_k127_4594667_26 Major facilitator superfamily K08161 - - 0.00006682 55.0
PYH1_k127_4594667_27 SMART TRASH domain protein - - - 0.0004623 46.0
PYH1_k127_4594667_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
PYH1_k127_4594667_4 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 322.0
PYH1_k127_4594667_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 337.0
PYH1_k127_4594667_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000685 261.0
PYH1_k127_4594667_7 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 262.0
PYH1_k127_4594667_8 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000321 257.0
PYH1_k127_4594667_9 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001811 247.0
PYH1_k127_4682955_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.184e-271 854.0
PYH1_k127_4682955_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 553.0
PYH1_k127_4682955_10 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
PYH1_k127_4682955_11 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000006747 204.0
PYH1_k127_4682955_12 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
PYH1_k127_4682955_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000149 181.0
PYH1_k127_4682955_14 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000001075 160.0
PYH1_k127_4682955_15 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000002926 151.0
PYH1_k127_4682955_16 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000001897 141.0
PYH1_k127_4682955_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000008066 128.0
PYH1_k127_4682955_18 protein conserved in bacteria - - - 0.000002191 59.0
PYH1_k127_4682955_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000008665 53.0
PYH1_k127_4682955_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 504.0
PYH1_k127_4682955_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 444.0
PYH1_k127_4682955_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 406.0
PYH1_k127_4682955_5 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 387.0
PYH1_k127_4682955_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 340.0
PYH1_k127_4682955_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000003549 254.0
PYH1_k127_4682955_8 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000005554 232.0
PYH1_k127_4682955_9 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000008016 226.0
PYH1_k127_4698657_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 625.0
PYH1_k127_4698657_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008653 278.0
PYH1_k127_4698657_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08256 - 2.4.1.345,2.7.8.5 0.000000000000000000000000000000000005949 143.0
PYH1_k127_4719158_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 476.0
PYH1_k127_4719158_1 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 434.0
PYH1_k127_4719158_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 301.0
PYH1_k127_4719158_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001874 252.0
PYH1_k127_4719158_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000002036 225.0
PYH1_k127_4719158_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000007159 213.0
PYH1_k127_4719158_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02035 - - 0.00000000000000000868 86.0
PYH1_k127_4719158_7 - - - - 0.0000000001624 67.0
PYH1_k127_4772639_0 DNA polymerase type-B family K02336 - 2.7.7.7 6.682e-223 715.0
PYH1_k127_4772639_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 382.0
PYH1_k127_4772639_10 DSBA-like thioredoxin domain - - - 0.000000000000000001585 92.0
PYH1_k127_4772639_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 340.0
PYH1_k127_4772639_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000243 250.0
PYH1_k127_4772639_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000005233 243.0
PYH1_k127_4772639_5 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000024 190.0
PYH1_k127_4772639_6 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000406 189.0
PYH1_k127_4772639_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000008521 193.0
PYH1_k127_4772639_8 dienelactone hydrolase - - - 0.000000000000000000000000000000003228 146.0
PYH1_k127_4772639_9 lipopolysaccharide transmembrane transporter activity K07058 - - 0.000000000000000000222 102.0
PYH1_k127_4806101_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K16901 - 1.14.14.8,1.14.14.9 4.649e-202 642.0
PYH1_k127_4806101_1 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 463.0
PYH1_k127_4806101_10 - - - - 0.000000002312 59.0
PYH1_k127_4806101_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 377.0
PYH1_k127_4806101_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 378.0
PYH1_k127_4806101_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 367.0
PYH1_k127_4806101_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 293.0
PYH1_k127_4806101_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002166 256.0
PYH1_k127_4806101_7 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000001903 206.0
PYH1_k127_4806101_8 SnoaL-like polyketide cyclase K07255 - - 0.0000000000000000000000000000000000000000000000000006287 188.0
PYH1_k127_4806101_9 - - - - 0.000000000000000000000000004581 112.0
PYH1_k127_4811991_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 596.0
PYH1_k127_4811991_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 353.0
PYH1_k127_4811991_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001001 267.0
PYH1_k127_4811991_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000004836 235.0
PYH1_k127_4811991_4 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000148 183.0
PYH1_k127_4811991_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000006863 191.0
PYH1_k127_4811991_6 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000002402 155.0
PYH1_k127_4811991_7 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000558 146.0
PYH1_k127_4821537_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 542.0
PYH1_k127_4821537_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 438.0
PYH1_k127_4821537_10 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000001397 119.0
PYH1_k127_4821537_11 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000722 106.0
PYH1_k127_4821537_2 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 310.0
PYH1_k127_4821537_3 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000623 279.0
PYH1_k127_4821537_4 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 262.0
PYH1_k127_4821537_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000009195 232.0
PYH1_k127_4821537_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002896 200.0
PYH1_k127_4821537_7 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000009932 178.0
PYH1_k127_4821537_8 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000004438 160.0
PYH1_k127_4821537_9 regulation of translation K03530 - - 0.0000000000000000000000000000001646 126.0
PYH1_k127_4868250_0 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 303.0
PYH1_k127_4868250_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000222 192.0
PYH1_k127_4868250_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000001315 173.0
PYH1_k127_4940982_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 3.829e-240 755.0
PYH1_k127_4940982_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 525.0
PYH1_k127_4940982_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00003,K00058,K01752,K16843 - 1.1.1.3,1.1.1.310,1.1.1.399,1.1.1.95,4.3.1.17 0.000000000000000000000000000000000000000000000000000000003092 215.0
PYH1_k127_4940982_11 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000001338 164.0
PYH1_k127_4940982_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002124 165.0
PYH1_k127_4940982_13 Thioredoxin - - - 0.00000000000000000000000001749 124.0
PYH1_k127_4940982_14 - - - - 0.0000000004549 63.0
PYH1_k127_4940982_15 - - - - 0.00000006509 60.0
PYH1_k127_4940982_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 314.0
PYH1_k127_4940982_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 319.0
PYH1_k127_4940982_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 293.0
PYH1_k127_4940982_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003824 288.0
PYH1_k127_4940982_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000003151 248.0
PYH1_k127_4940982_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000001364 250.0
PYH1_k127_4940982_8 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000002087 241.0
PYH1_k127_4940982_9 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000001049 218.0
PYH1_k127_4989852_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.024e-217 689.0
PYH1_k127_4989852_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
PYH1_k127_4989852_2 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000005729 246.0
PYH1_k127_4989852_3 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000006691 191.0
PYH1_k127_4989852_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000001198 109.0
PYH1_k127_4989852_5 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000001456 96.0
PYH1_k127_4996105_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 529.0
PYH1_k127_4996105_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 356.0
PYH1_k127_4996105_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
PYH1_k127_4996105_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 306.0
PYH1_k127_4996105_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000002817 186.0
PYH1_k127_4996105_5 adenylylsulfate kinase activity K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000001596 173.0
PYH1_k127_4996105_6 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000002146 104.0
PYH1_k127_4996105_7 PFAM UspA domain protein - - - 0.00000000000000000000007129 104.0
PYH1_k127_4996105_8 Belongs to the universal stress protein A family - - - 0.0000000000000000000007207 102.0
PYH1_k127_4996105_9 Universal stress protein - - - 0.0000000000000000232 87.0
PYH1_k127_5050840_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 505.0
PYH1_k127_5050840_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 449.0
PYH1_k127_5050840_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 445.0
PYH1_k127_5050840_3 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 288.0
PYH1_k127_5050840_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000001395 201.0
PYH1_k127_5050840_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000008676 95.0
PYH1_k127_5074151_0 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 540.0
PYH1_k127_5074151_1 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 433.0
PYH1_k127_5077385_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 523.0
PYH1_k127_5077385_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 352.0
PYH1_k127_5077385_2 Glutathionylspermidine synthase preATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 328.0
PYH1_k127_5080945_0 Animal haem peroxidase - - - 0.0 1288.0
PYH1_k127_5080945_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 570.0
PYH1_k127_5080945_10 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000001832 145.0
PYH1_k127_5080945_11 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000001114 142.0
PYH1_k127_5080945_12 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000000000000000000007094 100.0
PYH1_k127_5080945_13 - - - - 0.000000000000000000017 100.0
PYH1_k127_5080945_14 - - - - 0.00000000000000000003145 99.0
PYH1_k127_5080945_15 - - - - 0.000000000001003 72.0
PYH1_k127_5080945_2 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 510.0
PYH1_k127_5080945_3 lipoprotein transporter activity K02003 GO:0008150,GO:0009405,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002454 263.0
PYH1_k127_5080945_4 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000004228 230.0
PYH1_k127_5080945_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000006513 222.0
PYH1_k127_5080945_6 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000000002755 195.0
PYH1_k127_5080945_7 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000000000000000494 181.0
PYH1_k127_5080945_8 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000482 182.0
PYH1_k127_5080945_9 - - - - 0.0000000000000000000000000000000000000000000003562 185.0
PYH1_k127_5101553_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 455.0
PYH1_k127_5101553_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001724 287.0
PYH1_k127_5102402_0 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000002427 220.0
PYH1_k127_5102402_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000006387 214.0
PYH1_k127_5102402_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000003108 149.0
PYH1_k127_5102402_3 FtsX-like permease family K02004 - - 0.00000004255 55.0
PYH1_k127_5113302_0 Belongs to the GcvT family K19191 - 1.5.3.19 0.0 1043.0
PYH1_k127_5113302_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 577.0
PYH1_k127_5113302_10 PFAM Lipase, class 3 K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
PYH1_k127_5113302_11 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000244 271.0
PYH1_k127_5113302_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000007008 212.0
PYH1_k127_5113302_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000518 188.0
PYH1_k127_5113302_14 Putative regulatory protein - - - 0.000000000000000000000000000000000001081 143.0
PYH1_k127_5113302_15 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000007638 136.0
PYH1_k127_5113302_16 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00007118 52.0
PYH1_k127_5113302_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 515.0
PYH1_k127_5113302_3 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 458.0
PYH1_k127_5113302_4 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 416.0
PYH1_k127_5113302_5 atp-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 429.0
PYH1_k127_5113302_6 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 391.0
PYH1_k127_5113302_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 370.0
PYH1_k127_5113302_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
PYH1_k127_5113302_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005706 281.0
PYH1_k127_5123792_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 321.0
PYH1_k127_5123792_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 322.0
PYH1_k127_5123792_2 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000001472 248.0
PYH1_k127_5123792_3 Histidine kinase K02482,K03557 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000002172 207.0
PYH1_k127_5123792_4 Flavin-nucleotide-binding protein K07005 - - 0.00000000000000000007487 98.0
PYH1_k127_5135598_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 351.0
PYH1_k127_5135598_1 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 358.0
PYH1_k127_5135598_2 Bifunctional protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000005382 266.0
PYH1_k127_5135598_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000000000000000000002068 253.0
PYH1_k127_5135598_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000003249 220.0
PYH1_k127_5135598_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000005466 91.0
PYH1_k127_5154744_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1154.0
PYH1_k127_5154744_1 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000524 144.0
PYH1_k127_5154744_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000002156 117.0
PYH1_k127_5156757_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 5.051e-234 745.0
PYH1_k127_5156757_1 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 494.0
PYH1_k127_5156757_10 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000009142 186.0
PYH1_k127_5156757_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000003715 160.0
PYH1_k127_5156757_12 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000001077 155.0
PYH1_k127_5156757_13 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000001472 140.0
PYH1_k127_5156757_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001193 144.0
PYH1_k127_5156757_15 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000004545 139.0
PYH1_k127_5156757_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000003046 121.0
PYH1_k127_5156757_17 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000004203 113.0
PYH1_k127_5156757_18 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000002091 109.0
PYH1_k127_5156757_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001013 108.0
PYH1_k127_5156757_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 499.0
PYH1_k127_5156757_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.00000000000000000000005717 110.0
PYH1_k127_5156757_21 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000003611 76.0
PYH1_k127_5156757_22 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000001675 61.0
PYH1_k127_5156757_23 Protein of unknown function (DUF2889) - - - 0.00000007085 64.0
PYH1_k127_5156757_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 482.0
PYH1_k127_5156757_4 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 487.0
PYH1_k127_5156757_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 412.0
PYH1_k127_5156757_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 384.0
PYH1_k127_5156757_7 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 314.0
PYH1_k127_5156757_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 319.0
PYH1_k127_5156757_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003719 237.0
PYH1_k127_5161146_0 ABC transporter K03701 - - 0.0 1257.0
PYH1_k127_5161146_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 551.0
PYH1_k127_5161146_10 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000001507 218.0
PYH1_k127_5161146_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000005985 200.0
PYH1_k127_5161146_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000003613 181.0
PYH1_k127_5161146_13 Metal binding domain of Ada K00567 - 2.1.1.63 0.00000000000000000000000000000000000001658 156.0
PYH1_k127_5161146_14 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000647 136.0
PYH1_k127_5161146_15 Thioredoxin domain - - - 0.0000000000000000000000000000006122 126.0
PYH1_k127_5161146_16 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000001003 119.0
PYH1_k127_5161146_18 Thioredoxin domain - - - 0.0000000000000000001093 90.0
PYH1_k127_5161146_19 Acyl dehydratase - - - 0.00000000000000001822 94.0
PYH1_k127_5161146_2 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 479.0
PYH1_k127_5161146_20 DinB superfamily - - - 0.000000000000004813 81.0
PYH1_k127_5161146_21 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000005223 67.0
PYH1_k127_5161146_22 N-terminal half of MaoC dehydratase - - - 0.0000001907 63.0
PYH1_k127_5161146_3 Pyruvate kinase, alpha/beta domain K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 422.0
PYH1_k127_5161146_4 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 373.0
PYH1_k127_5161146_5 Dienelactone hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 317.0
PYH1_k127_5161146_6 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 301.0
PYH1_k127_5161146_7 amp-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 309.0
PYH1_k127_5161146_8 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 272.0
PYH1_k127_5161146_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002226 234.0
PYH1_k127_5182833_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 566.0
PYH1_k127_5182833_1 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 371.0
PYH1_k127_5182833_11 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000002516 94.0
PYH1_k127_5182833_12 protein conserved in bacteria K11904 - - 0.0000000000001436 76.0
PYH1_k127_5182833_13 Tripartite tricarboxylate transporter TctB family - - - 0.00000001204 63.0
PYH1_k127_5182833_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 360.0
PYH1_k127_5182833_3 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001398 289.0
PYH1_k127_5182833_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000019 250.0
PYH1_k127_5182833_5 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000008802 219.0
PYH1_k127_5182833_6 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000008128 208.0
PYH1_k127_5182833_7 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001771 180.0
PYH1_k127_5182833_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000002414 153.0
PYH1_k127_5192056_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 378.0
PYH1_k127_5192056_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000001043 74.0
PYH1_k127_5192056_2 Protein of unknown function (DUF971) - - - 0.00004266 50.0
PYH1_k127_5194944_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 524.0
PYH1_k127_5194944_1 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001099 275.0
PYH1_k127_5194944_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000374 269.0
PYH1_k127_5194944_3 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000006812 151.0
PYH1_k127_5194944_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000001191 83.0
PYH1_k127_5194944_5 AMP-binding enzyme C-terminal domain K00666 - - 0.000000004635 63.0
PYH1_k127_5203839_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 6.361e-205 647.0
PYH1_k127_5203839_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 593.0
PYH1_k127_5203839_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 441.0
PYH1_k127_5203839_3 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000003958 229.0
PYH1_k127_5203839_4 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000178 226.0
PYH1_k127_5203839_5 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000001451 172.0
PYH1_k127_5203839_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000003694 126.0
PYH1_k127_5203839_7 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000001732 123.0
PYH1_k127_5215197_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 522.0
PYH1_k127_5215197_1 Two component signalling adaptor domain K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 447.0
PYH1_k127_5215197_10 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000007327 149.0
PYH1_k127_5215197_11 phosphorelay signal transduction system K02658 - - 0.0000000000000000000000000000000001062 137.0
PYH1_k127_5215197_12 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000001308 136.0
PYH1_k127_5215197_13 Conserved TM helix - - - 0.0000000000000000000000000005284 121.0
PYH1_k127_5215197_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000002744 69.0
PYH1_k127_5215197_15 chemotaxis K02659,K03408 - - 0.00000000001457 71.0
PYH1_k127_5215197_2 transmembrane signaling receptor activity K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 395.0
PYH1_k127_5215197_3 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 325.0
PYH1_k127_5215197_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001733 268.0
PYH1_k127_5215197_5 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
PYH1_k127_5215197_6 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 266.0
PYH1_k127_5215197_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
PYH1_k127_5215197_8 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002694 273.0
PYH1_k127_5215197_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000002939 245.0
PYH1_k127_5243361_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.371e-298 940.0
PYH1_k127_5243361_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 2.05e-205 655.0
PYH1_k127_5243361_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 341.0
PYH1_k127_5243361_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
PYH1_k127_5243361_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000917 214.0
PYH1_k127_5243361_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000000000000004251 211.0
PYH1_k127_5252378_0 PASTA domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 505.0
PYH1_k127_5252378_1 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 480.0
PYH1_k127_5252378_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000001757 230.0
PYH1_k127_5276341_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 443.0
PYH1_k127_5276341_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000738 214.0
PYH1_k127_5276341_2 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000001815 179.0
PYH1_k127_5284012_0 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 560.0
PYH1_k127_5284012_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 454.0
PYH1_k127_5284012_10 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003561 267.0
PYH1_k127_5284012_11 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000007272 245.0
PYH1_k127_5284012_12 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001613 243.0
PYH1_k127_5284012_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000228 243.0
PYH1_k127_5284012_14 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000005421 229.0
PYH1_k127_5284012_15 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000003712 225.0
PYH1_k127_5284012_16 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000004333 203.0
PYH1_k127_5284012_17 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000008985 161.0
PYH1_k127_5284012_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000127 153.0
PYH1_k127_5284012_2 ABC-type multidrug transport system ATPase and permease K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 424.0
PYH1_k127_5284012_20 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000002096 132.0
PYH1_k127_5284012_21 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000001747 119.0
PYH1_k127_5284012_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000001405 94.0
PYH1_k127_5284012_23 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.00000000000000000002903 98.0
PYH1_k127_5284012_24 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009536,GO:0009636,GO:0009941,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0031967,GO:0031975,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051302,GO:0051716,GO:0051781,GO:0055114,GO:0065007,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.0000000000000000001032 89.0
PYH1_k127_5284012_25 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000001317 81.0
PYH1_k127_5284012_26 DinB family - - - 0.0000000000001432 81.0
PYH1_k127_5284012_27 Redoxin - - - 0.0000000000002244 70.0
PYH1_k127_5284012_28 Tetratricopeptide repeat - - - 0.000000000001389 77.0
PYH1_k127_5284012_29 Short repeat of unknown function (DUF308) - - - 0.0000000000058 74.0
PYH1_k127_5284012_3 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 349.0
PYH1_k127_5284012_30 Domain of unknown function (DUF4149) - - - 0.000001984 53.0
PYH1_k127_5284012_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 334.0
PYH1_k127_5284012_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
PYH1_k127_5284012_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
PYH1_k127_5284012_7 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 293.0
PYH1_k127_5284012_8 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001644 287.0
PYH1_k127_5284012_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
PYH1_k127_5302770_0 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 432.0
PYH1_k127_5302770_1 PFAM Septum formation initiator K05589,K13052 - - 0.0000001992 60.0
PYH1_k127_5302770_2 transferase activity, transferring glycosyl groups - - - 0.00004465 55.0
PYH1_k127_5304887_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 477.0
PYH1_k127_5304887_1 shikimate 3-dehydrogenase (NADP+) activity K00800,K10669 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19,2.7.1.160 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 452.0
PYH1_k127_5304887_2 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 314.0
PYH1_k127_5304887_3 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000007195 256.0
PYH1_k127_5304887_4 - - - - 0.0000000000000000000000001577 114.0
PYH1_k127_5304887_5 cyclic nucleotide-binding - - - 0.0000000000000062 84.0
PYH1_k127_5316791_0 Metallopeptidase family M24 - - - 6.328e-199 631.0
PYH1_k127_5316791_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 575.0
PYH1_k127_5316791_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 368.0
PYH1_k127_5316791_3 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 361.0
PYH1_k127_5316791_4 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001743 229.0
PYH1_k127_5316791_5 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000169 206.0
PYH1_k127_5316791_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000001087 115.0
PYH1_k127_5316791_7 PIN domain - - - 0.00000000000000000002211 96.0
PYH1_k127_5316791_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000003872 76.0
PYH1_k127_5316791_9 Protein of unknown function (DUF1285) K09986 - - 0.00000000002191 70.0
PYH1_k127_5341307_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 368.0
PYH1_k127_5341307_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 292.0
PYH1_k127_5341307_2 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009291 254.0
PYH1_k127_5341307_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007033 253.0
PYH1_k127_5341307_4 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000001913 151.0
PYH1_k127_5341307_5 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000001035 135.0
PYH1_k127_5341307_6 PFAM membrane protein of K08972 - - 0.00000000000000000000000004068 111.0
PYH1_k127_5341307_7 major facilitator superfamily - - - 0.0000000000162 69.0
PYH1_k127_5341307_8 Redoxin - - - 0.000000983 56.0
PYH1_k127_5353195_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 3.132e-282 883.0
PYH1_k127_5353195_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 593.0
PYH1_k127_5353195_10 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000002526 179.0
PYH1_k127_5353195_11 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000852 169.0
PYH1_k127_5353195_12 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000001256 99.0
PYH1_k127_5353195_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 488.0
PYH1_k127_5353195_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 436.0
PYH1_k127_5353195_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 418.0
PYH1_k127_5353195_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 346.0
PYH1_k127_5353195_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
PYH1_k127_5353195_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 313.0
PYH1_k127_5353195_8 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 304.0
PYH1_k127_5353195_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 300.0
PYH1_k127_5477527_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.249e-269 854.0
PYH1_k127_5477527_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 599.0
PYH1_k127_5477527_2 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 323.0
PYH1_k127_5477527_3 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000004004 239.0
PYH1_k127_5477527_4 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000002233 190.0
PYH1_k127_5477527_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000005982 111.0
PYH1_k127_5477527_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000006002 87.0
PYH1_k127_549100_0 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 299.0
PYH1_k127_549100_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001577 287.0
PYH1_k127_549100_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 259.0
PYH1_k127_549100_3 Transports peptides consisting of two or three amino acids K02033 - - 0.000000000000000000000000000000000009512 139.0
PYH1_k127_5557585_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 569.0
PYH1_k127_5557585_1 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 495.0
PYH1_k127_5557585_2 spermidine putrescine ABC transporter, permease K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
PYH1_k127_5557585_3 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000001641 230.0
PYH1_k127_5557585_4 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000000000000000000000001204 167.0
PYH1_k127_5557585_5 ABC transporter permease K02054 - - 0.000000000000000005855 85.0
PYH1_k127_557932_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 386.0
PYH1_k127_557932_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000006132 177.0
PYH1_k127_557932_2 SNARE associated Golgi protein - - - 0.000000000000002111 84.0
PYH1_k127_5631662_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1312.0
PYH1_k127_5631662_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1140.0
PYH1_k127_5631662_10 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000002281 93.0
PYH1_k127_5631662_11 Amidohydrolase family - - - 0.000000002311 61.0
PYH1_k127_5631662_2 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 382.0
PYH1_k127_5631662_3 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 371.0
PYH1_k127_5631662_4 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 369.0
PYH1_k127_5631662_5 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 326.0
PYH1_k127_5631662_6 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 331.0
PYH1_k127_5631662_7 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000006002 113.0
PYH1_k127_5631662_8 Glycine oxidase K00285 - 1.4.5.1 0.0000000000000000000000001386 114.0
PYH1_k127_5631662_9 IMP dehydrogenase activity K04767 - - 0.000000000000000002117 92.0
PYH1_k127_56374_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 1e-323 1002.0
PYH1_k127_56374_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 2.083e-200 636.0
PYH1_k127_56374_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 554.0
PYH1_k127_56374_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
PYH1_k127_56374_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 319.0
PYH1_k127_56374_5 Alpha beta hydrolase superfamily K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001784 288.0
PYH1_k127_56374_6 DinB family - - - 0.00000000000000000000000000001156 124.0
PYH1_k127_56374_7 - - - - 0.00000000000000000000000105 112.0
PYH1_k127_56374_8 chemotaxis protein K06595 GO:0003674,GO:0005488,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0020037,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0046906,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:1901363 - 0.0001122 52.0
PYH1_k127_5743797_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 334.0
PYH1_k127_5743797_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 309.0
PYH1_k127_5743797_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000002966 196.0
PYH1_k127_5743797_3 HDOD domain - - - 0.00000000000000000000000000000000000002275 157.0
PYH1_k127_5743797_4 Sulfurtransferase TusA - - - 0.0000000000000000004907 90.0
PYH1_k127_5817386_0 ABC transporter - - - 3.231e-268 835.0
PYH1_k127_5817386_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 547.0
PYH1_k127_5817386_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 419.0
PYH1_k127_5817386_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 385.0
PYH1_k127_5817386_4 amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 366.0
PYH1_k127_5817386_5 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 347.0
PYH1_k127_5847931_0 PFAM Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 340.0
PYH1_k127_5847931_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
PYH1_k127_5847931_2 branched-chain amino acid ABC transporter ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
PYH1_k127_5847931_3 Dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009574 283.0
PYH1_k127_5847931_4 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004676 258.0
PYH1_k127_5847931_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000009079 222.0
PYH1_k127_5847931_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000006153 83.0
PYH1_k127_5862957_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 9.19e-197 631.0
PYH1_k127_5862957_1 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 478.0
PYH1_k127_5862957_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000005572 152.0
PYH1_k127_5862957_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 379.0
PYH1_k127_5862957_3 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 324.0
PYH1_k127_5862957_4 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 308.0
PYH1_k127_5862957_5 Wzy family polymerase, exosortase system type 1 associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 303.0
PYH1_k127_5862957_6 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000004567 224.0
PYH1_k127_5862957_7 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000009861 215.0
PYH1_k127_5862957_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000008622 195.0
PYH1_k127_5862957_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001353 181.0
PYH1_k127_5879896_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
PYH1_k127_5879896_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003176 281.0
PYH1_k127_5879896_2 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
PYH1_k127_5879896_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000006487 156.0
PYH1_k127_5879896_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000005177 102.0
PYH1_k127_5879896_5 - - - - 0.00000000000000127 80.0
PYH1_k127_5881427_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1084.0
PYH1_k127_5881427_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 8.469e-221 703.0
PYH1_k127_5881427_10 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 323.0
PYH1_k127_5881427_11 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000003753 261.0
PYH1_k127_5881427_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000002193 221.0
PYH1_k127_5881427_13 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000001195 220.0
PYH1_k127_5881427_14 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000003537 218.0
PYH1_k127_5881427_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000005809 210.0
PYH1_k127_5881427_16 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000004411 211.0
PYH1_k127_5881427_17 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000001543 200.0
PYH1_k127_5881427_18 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000001102 189.0
PYH1_k127_5881427_19 PFAM Bacterial regulatory proteins, gntR family K05799 - - 0.000000000000000000000000000000000000000000003439 173.0
PYH1_k127_5881427_2 protein conserved in bacteria K07793 - - 3.359e-218 687.0
PYH1_k127_5881427_20 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000007202 135.0
PYH1_k127_5881427_21 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000003634 82.0
PYH1_k127_5881427_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 516.0
PYH1_k127_5881427_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 520.0
PYH1_k127_5881427_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 488.0
PYH1_k127_5881427_6 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 434.0
PYH1_k127_5881427_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 431.0
PYH1_k127_5881427_8 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 398.0
PYH1_k127_5881427_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 396.0
PYH1_k127_5895441_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 2.964e-228 732.0
PYH1_k127_5895441_1 PFAM ABC transporter K15738 - - 1.871e-196 629.0
PYH1_k127_5895441_10 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
PYH1_k127_5895441_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000006747 145.0
PYH1_k127_5895441_12 Glyoxalase-like domain - - - 0.00000000000000000000000000004034 128.0
PYH1_k127_5895441_13 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000009109 98.0
PYH1_k127_5895441_14 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K09459 - 4.1.1.82 0.000000007473 65.0
PYH1_k127_5895441_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 523.0
PYH1_k127_5895441_3 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 354.0
PYH1_k127_5895441_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 338.0
PYH1_k127_5895441_5 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 331.0
PYH1_k127_5895441_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 321.0
PYH1_k127_5895441_7 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
PYH1_k127_5895441_8 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 311.0
PYH1_k127_5895441_9 Methyltransferase fkbm family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002993 240.0
PYH1_k127_5899536_0 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 488.0
PYH1_k127_5899536_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 483.0
PYH1_k127_5899536_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 359.0
PYH1_k127_5899536_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000431 128.0
PYH1_k127_5911100_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004299 269.0
PYH1_k127_5911100_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 257.0
PYH1_k127_5911100_2 Major Facilitator Superfamily K02445 GO:0005575,GO:0005576 - 0.00000000000000000189 96.0
PYH1_k127_5952336_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.226e-222 702.0
PYH1_k127_5952336_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 387.0
PYH1_k127_5952336_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
PYH1_k127_5952336_3 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 300.0
PYH1_k127_5952336_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000005649 119.0
PYH1_k127_5952336_5 Ferredoxin - - - 0.000000000000000000003039 98.0
PYH1_k127_5952336_6 Protein of unknown function (DUF448) K07742 - - 0.00000000000000001143 85.0
PYH1_k127_5952336_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000001617 57.0
PYH1_k127_5993443_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 358.0
PYH1_k127_5993443_1 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000001447 221.0
PYH1_k127_5993443_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000009512 144.0
PYH1_k127_5993443_4 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.0000000000000000000000003736 112.0
PYH1_k127_5993443_5 membrane K15977 - - 0.00000000000001075 81.0
PYH1_k127_5993443_6 CarboxypepD_reg-like domain - - - 0.0008503 49.0
PYH1_k127_603349_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.533e-194 617.0
PYH1_k127_603349_1 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 365.0
PYH1_k127_603349_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
PYH1_k127_603349_3 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000222 262.0
PYH1_k127_603349_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009036 256.0
PYH1_k127_603349_5 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000008043 187.0
PYH1_k127_603349_6 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000035 131.0
PYH1_k127_604029_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 417.0
PYH1_k127_604029_1 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 363.0
PYH1_k127_604029_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 362.0
PYH1_k127_604029_3 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 315.0
PYH1_k127_604029_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 291.0
PYH1_k127_604029_5 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000003577 174.0
PYH1_k127_604029_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000002356 171.0
PYH1_k127_6044466_0 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000003778 252.0
PYH1_k127_6044466_1 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001078 255.0
PYH1_k127_6044466_2 Thioredoxin - - - 0.00000000000000000000000000000000000001341 154.0
PYH1_k127_6044466_3 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000000532 130.0
PYH1_k127_6044466_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00002283 49.0
PYH1_k127_6097977_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 323.0
PYH1_k127_6097977_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
PYH1_k127_6097977_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003866 258.0
PYH1_k127_6097977_3 TIGR00255 family - - - 0.00000000000000000000000000000000000000000000000000000000000000001902 235.0
PYH1_k127_6097977_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000003845 205.0
PYH1_k127_6097977_5 endonuclease activity - - - 0.0000000000000000000000000000000004146 139.0
PYH1_k127_6097977_6 NMT1-like family K02051,K15553 - - 0.0001148 54.0
PYH1_k127_6097977_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0007889 49.0
PYH1_k127_6122507_0 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 398.0
PYH1_k127_6122507_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
PYH1_k127_6122507_10 Histidine kinase - - - 0.00007813 49.0
PYH1_k127_6122507_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007412 302.0
PYH1_k127_6122507_3 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000517 267.0
PYH1_k127_6122507_4 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.00000000000000000000000000000000000000000000000000000000004496 211.0
PYH1_k127_6122507_5 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000007122 197.0
PYH1_k127_6122507_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001265 159.0
PYH1_k127_6122507_7 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000442 142.0
PYH1_k127_6122507_8 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000001729 65.0
PYH1_k127_6122507_9 - - - - 0.00000002158 58.0
PYH1_k127_6152173_0 Radical SAM - - - 1.604e-213 675.0
PYH1_k127_6152173_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 511.0
PYH1_k127_6152173_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 488.0
PYH1_k127_6152173_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004933 250.0
PYH1_k127_6152173_4 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000001957 197.0
PYH1_k127_6152173_5 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.000000000000000000000000000000001226 138.0
PYH1_k127_6152173_6 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000002989 147.0
PYH1_k127_6152173_7 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000003408 91.0
PYH1_k127_6152173_8 DUF218 domain - - - 0.00000003243 65.0
PYH1_k127_6152173_9 - - - - 0.0001721 50.0
PYH1_k127_6186993_0 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 257.0
PYH1_k127_6186993_1 GTP binding K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
PYH1_k127_6186993_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000003874 123.0
PYH1_k127_6186993_3 Roadblock/LC7 domain - - - 0.000000000000000000000000001725 119.0
PYH1_k127_6186993_4 Trypsin-like peptidase domain - - - 0.00000000000000006319 94.0
PYH1_k127_6186993_5 PFAM Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.0000000003586 66.0
PYH1_k127_6186993_6 Haem-degrading - - - 0.00000001217 62.0
PYH1_k127_6186993_7 Tetratricopeptide repeat - - - 0.0001246 53.0
PYH1_k127_6232382_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1298.0
PYH1_k127_6232382_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1047.0
PYH1_k127_6232382_10 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000003325 239.0
PYH1_k127_6232382_11 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000002086 232.0
PYH1_k127_6232382_12 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001558 214.0
PYH1_k127_6232382_13 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000002117 205.0
PYH1_k127_6232382_14 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000002444 188.0
PYH1_k127_6232382_15 Polymer-forming cytoskeletal - - - 0.0000000000000000000002154 102.0
PYH1_k127_6232382_16 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000004426 108.0
PYH1_k127_6232382_17 PAP2 superfamily - - - 0.0000000008562 66.0
PYH1_k127_6232382_18 protein transport across the cell outer membrane K02453,K03219 - - 0.00002353 55.0
PYH1_k127_6232382_19 protein trimerization - - - 0.0005852 51.0
PYH1_k127_6232382_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 9.297e-213 677.0
PYH1_k127_6232382_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 512.0
PYH1_k127_6232382_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 420.0
PYH1_k127_6232382_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 415.0
PYH1_k127_6232382_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
PYH1_k127_6232382_7 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 290.0
PYH1_k127_6232382_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005674 268.0
PYH1_k127_6232382_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000008925 263.0
PYH1_k127_6259255_0 Rieske 2Fe-2S domain protein K16319,K18074,K18242 - 1.14.12.1,1.14.12.15,1.14.13.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 541.0
PYH1_k127_6259255_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 510.0
PYH1_k127_6259255_10 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000007788 180.0
PYH1_k127_6259255_11 PFAM RES domain - - - 0.000000000000000000000000000000000000000000002274 168.0
PYH1_k127_6259255_12 DinB superfamily - - - 0.00000000000000000000000000000000000000001134 162.0
PYH1_k127_6259255_13 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000004514 168.0
PYH1_k127_6259255_14 Glyoxalase-like domain K08234 - - 0.00000000000000000000000000000000000008069 147.0
PYH1_k127_6259255_15 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000001238 145.0
PYH1_k127_6259255_16 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000005398 131.0
PYH1_k127_6259255_18 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000005842 113.0
PYH1_k127_6259255_19 Sporulation related domain - - - 0.00003019 51.0
PYH1_k127_6259255_2 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 337.0
PYH1_k127_6259255_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 314.0
PYH1_k127_6259255_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02032,K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 310.0
PYH1_k127_6259255_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000117 254.0
PYH1_k127_6259255_6 amidohydrolase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000001487 254.0
PYH1_k127_6259255_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
PYH1_k127_6259255_8 Ring hydroxylating beta subunit K18075 - 1.14.12.15 0.00000000000000000000000000000000000000000000000001108 186.0
PYH1_k127_6259255_9 KR domain - - - 0.0000000000000000000000000000000000000000000000002509 186.0
PYH1_k127_6364956_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 5.05e-269 851.0
PYH1_k127_6364956_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding K00179 - 1.2.7.8 2.283e-257 821.0
PYH1_k127_6364956_10 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001558 269.0
PYH1_k127_6364956_11 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000003368 231.0
PYH1_k127_6364956_12 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000006005 228.0
PYH1_k127_6364956_13 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000001939 220.0
PYH1_k127_6364956_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000004591 194.0
PYH1_k127_6364956_15 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000002482 193.0
PYH1_k127_6364956_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000001311 168.0
PYH1_k127_6364956_17 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000005626 165.0
PYH1_k127_6364956_18 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000000001027 151.0
PYH1_k127_6364956_19 RNA cap guanine-N2 methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000001047 149.0
PYH1_k127_6364956_2 Acetamidase/Formamidase family - - - 6.28e-238 743.0
PYH1_k127_6364956_20 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000000001982 144.0
PYH1_k127_6364956_21 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000001709 130.0
PYH1_k127_6364956_22 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000006002 109.0
PYH1_k127_6364956_23 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000002201 103.0
PYH1_k127_6364956_24 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000002278 92.0
PYH1_k127_6364956_25 Protein of unknown function (DUF2905) - - - 0.0000000000000000008138 97.0
PYH1_k127_6364956_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.33e-218 698.0
PYH1_k127_6364956_4 Protein export membrane protein K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 498.0
PYH1_k127_6364956_5 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 450.0
PYH1_k127_6364956_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 428.0
PYH1_k127_6364956_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 392.0
PYH1_k127_6364956_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 381.0
PYH1_k127_6364956_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 345.0
PYH1_k127_639560_0 Protein of unknown function, DUF255 K06888 - - 1.021e-239 761.0
PYH1_k127_639560_1 PFAM NAD-dependent epimerase dehydratase - - - 4.001e-226 715.0
PYH1_k127_639560_10 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
PYH1_k127_639560_11 Peptidase family M28 K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 343.0
PYH1_k127_639560_12 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
PYH1_k127_639560_13 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 321.0
PYH1_k127_639560_14 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
PYH1_k127_639560_15 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 283.0
PYH1_k127_639560_16 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002187 278.0
PYH1_k127_639560_17 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 270.0
PYH1_k127_639560_18 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
PYH1_k127_639560_19 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003912 263.0
PYH1_k127_639560_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 2.886e-210 664.0
PYH1_k127_639560_20 PFAM Dimethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009773 241.0
PYH1_k127_639560_21 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000001419 234.0
PYH1_k127_639560_22 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000008761 221.0
PYH1_k127_639560_23 domain protein K01992,K06994 - - 0.00000000000000000000000000000000000000000000000000000000000002608 228.0
PYH1_k127_639560_24 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH1_k127_639560_25 - - - - 0.00000000000000000000000000000000000000000000000002846 191.0
PYH1_k127_639560_26 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000008603 181.0
PYH1_k127_639560_27 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000000000000000001631 179.0
PYH1_k127_639560_28 KR domain - - - 0.0000000000000000000000000000000000000000000005705 175.0
PYH1_k127_639560_29 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000005325 175.0
PYH1_k127_639560_3 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 2.524e-199 631.0
PYH1_k127_639560_30 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000005508 145.0
PYH1_k127_639560_31 - - - - 0.0000000000000000000000000001285 121.0
PYH1_k127_639560_32 carboxylic ester hydrolase activity - - - 0.00000000000000000000000001363 127.0
PYH1_k127_639560_33 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000008046 107.0
PYH1_k127_639560_34 Rieske [2Fe-2S] domain - - - 0.00000000000000000000005058 102.0
PYH1_k127_639560_35 X-Pro dipeptidyl-peptidase (S15 family) K06889,K07397 - - 0.00000000000003002 84.0
PYH1_k127_639560_36 thiamine biosynthesis protein ThiS K03154 - - 0.0000000002734 64.0
PYH1_k127_639560_37 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000005869 64.0
PYH1_k127_639560_38 Carboxymuconolactone decarboxylase family - - - 0.00000007087 61.0
PYH1_k127_639560_39 - - - - 0.0000001776 59.0
PYH1_k127_639560_4 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 588.0
PYH1_k127_639560_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 516.0
PYH1_k127_639560_6 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 489.0
PYH1_k127_639560_7 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 471.0
PYH1_k127_639560_8 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 454.0
PYH1_k127_639560_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 384.0
PYH1_k127_6397181_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 319.0
PYH1_k127_6397181_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000001066 183.0
PYH1_k127_6397181_2 PFAM beta-lactamase domain protein K00784 - 3.1.26.11 0.00000000000000000000000000000000000000003251 163.0
PYH1_k127_6397181_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000002799 134.0
PYH1_k127_6436904_0 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 313.0
PYH1_k127_6436904_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000002868 155.0
PYH1_k127_6436904_2 Periplasmic binding protein domain - - - 0.0003521 45.0
PYH1_k127_6440372_0 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 404.0
PYH1_k127_6440372_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 391.0
PYH1_k127_6440372_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000006557 224.0
PYH1_k127_6440372_3 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000002113 187.0
PYH1_k127_6440372_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000008549 191.0
PYH1_k127_6440372_5 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000002299 184.0
PYH1_k127_6440372_6 MaoC like domain - - - 0.0000000000000000000000000000000000000256 157.0
PYH1_k127_6440372_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000009823 121.0
PYH1_k127_6440372_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000005479 109.0
PYH1_k127_648433_0 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 470.0
PYH1_k127_648433_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 349.0
PYH1_k127_648433_2 UDP binding domain K00012,K00066,K02472,K02474,K13015 - 1.1.1.132,1.1.1.136,1.1.1.22,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 357.0
PYH1_k127_648433_3 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 349.0
PYH1_k127_648433_4 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 338.0
PYH1_k127_648433_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000002033 196.0
PYH1_k127_648433_6 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000849 179.0
PYH1_k127_6513721_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.635e-222 705.0
PYH1_k127_6513721_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 548.0
PYH1_k127_6513721_10 Flavin reductase like domain - - - 0.00000000000000000000000000000000000001414 149.0
PYH1_k127_6513721_11 methyltransferase - - - 0.000000000000000000000000000000000004587 156.0
PYH1_k127_6513721_12 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000002646 147.0
PYH1_k127_6513721_13 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000254 140.0
PYH1_k127_6513721_14 OsmC-like protein K06889,K07397 - - 0.000000000000002055 78.0
PYH1_k127_6513721_15 Belongs to the peptidase S1C family - - - 0.000000000000003656 85.0
PYH1_k127_6513721_16 Lrp/AsnC ligand binding domain - - - 0.000000007411 68.0
PYH1_k127_6513721_17 OsmC-like protein K06889,K07397 - - 0.00000002676 57.0
PYH1_k127_6513721_18 Phosphate acyltransferases - - - 0.0000917 51.0
PYH1_k127_6513721_19 Putative zinc-finger - - - 0.0001458 53.0
PYH1_k127_6513721_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 505.0
PYH1_k127_6513721_3 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 414.0
PYH1_k127_6513721_4 carbamoyl transferase, NodU family K00612,K16035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 411.0
PYH1_k127_6513721_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 323.0
PYH1_k127_6513721_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000001798 244.0
PYH1_k127_6513721_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002387 241.0
PYH1_k127_6513721_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000001648 236.0
PYH1_k127_6513721_9 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000003024 196.0
PYH1_k127_6548836_0 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 621.0
PYH1_k127_6548836_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 336.0
PYH1_k127_6548836_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 336.0
PYH1_k127_6548836_3 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000004304 175.0
PYH1_k127_6548836_4 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000005538 147.0
PYH1_k127_6572810_0 Drug exporters of the RND superfamily K06994 - - 2.625e-228 729.0
PYH1_k127_6572810_1 Carboxyl transferase domain - - - 6.148e-209 671.0
PYH1_k127_6572810_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 347.0
PYH1_k127_6572810_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004926 277.0
PYH1_k127_6572810_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001045 245.0
PYH1_k127_6572810_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000003799 233.0
PYH1_k127_6572810_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000214 242.0
PYH1_k127_6572810_15 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000003032 230.0
PYH1_k127_6572810_16 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000001878 211.0
PYH1_k127_6572810_17 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000001121 212.0
PYH1_k127_6572810_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000003091 198.0
PYH1_k127_6572810_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000001681 173.0
PYH1_k127_6572810_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 9.564e-199 630.0
PYH1_k127_6572810_20 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000003463 181.0
PYH1_k127_6572810_21 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000001045 166.0
PYH1_k127_6572810_22 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000001223 145.0
PYH1_k127_6572810_23 DinB superfamily K07552 - - 0.000000000000000000000000000001723 129.0
PYH1_k127_6572810_25 Biotin-lipoyl like - - - 0.000000000000000004221 86.0
PYH1_k127_6572810_26 Belongs to the UPF0312 family - - - 0.0000000009277 68.0
PYH1_k127_6572810_27 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 - 1.1.1.267 0.00000004351 60.0
PYH1_k127_6572810_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 496.0
PYH1_k127_6572810_4 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 489.0
PYH1_k127_6572810_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 374.0
PYH1_k127_6572810_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 366.0
PYH1_k127_6572810_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 353.0
PYH1_k127_6572810_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
PYH1_k127_6572810_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 335.0
PYH1_k127_6610205_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 2.736e-194 614.0
PYH1_k127_6610205_1 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000000000000000000000000000001228 241.0
PYH1_k127_6610205_2 SNARE-like domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001792 232.0
PYH1_k127_6610205_3 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000003421 201.0
PYH1_k127_6610205_4 Glycine-zipper domain - - - 0.0000000007506 65.0
PYH1_k127_6610833_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.713e-221 699.0
PYH1_k127_6610833_1 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 569.0
PYH1_k127_6610833_10 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.000001143 59.0
PYH1_k127_6610833_11 SMART CBS domain containing protein K00974 - 2.7.7.72 0.00002308 50.0
PYH1_k127_6610833_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 490.0
PYH1_k127_6610833_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 405.0
PYH1_k127_6610833_4 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 372.0
PYH1_k127_6610833_5 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 359.0
PYH1_k127_6610833_6 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 327.0
PYH1_k127_6610833_7 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 309.0
PYH1_k127_6610833_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000003853 169.0
PYH1_k127_6610833_9 OstA-like protein K09774 - - 0.00000000000000001626 92.0
PYH1_k127_6625042_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 516.0
PYH1_k127_6625042_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 443.0
PYH1_k127_6625042_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000001662 232.0
PYH1_k127_6625042_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000002703 127.0
PYH1_k127_6625042_4 integral membrane protein - - - 0.00000000000000000001179 99.0
PYH1_k127_667191_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.116e-279 869.0
PYH1_k127_667191_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 506.0
PYH1_k127_667191_2 CoA-transferase family III K07544,K07749 - 2.8.3.15,2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 431.0
PYH1_k127_667191_3 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 344.0
PYH1_k127_667191_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 305.0
PYH1_k127_667191_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003182 290.0
PYH1_k127_667191_6 Phosphate acyltransferases - - - 0.00000000001063 75.0
PYH1_k127_6744965_0 PFAM CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 340.0
PYH1_k127_6744965_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 332.0
PYH1_k127_6744965_2 peptidyl-tyrosine sulfation - - - 0.0000754 52.0
PYH1_k127_6747387_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 439.0
PYH1_k127_6747387_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 396.0
PYH1_k127_6747387_10 Outer membrane efflux protein K15725 - - 0.0000000009808 67.0
PYH1_k127_6747387_11 - - - - 0.00000003286 61.0
PYH1_k127_6747387_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 368.0
PYH1_k127_6747387_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 357.0
PYH1_k127_6747387_4 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 322.0
PYH1_k127_6747387_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 314.0
PYH1_k127_6747387_6 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000004809 224.0
PYH1_k127_6747387_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000001437 166.0
PYH1_k127_6747387_8 Lipoprotein - - - 0.000000000000007293 87.0
PYH1_k127_6747387_9 - - - - 0.000000000002051 69.0
PYH1_k127_6775082_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1117.0
PYH1_k127_6775082_1 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 436.0
PYH1_k127_6775082_2 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 318.0
PYH1_k127_6775082_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001366 282.0
PYH1_k127_6775082_4 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000149 255.0
PYH1_k127_6775082_5 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000000218 182.0
PYH1_k127_6775082_6 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000001411 119.0
PYH1_k127_6775082_7 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000002002 89.0
PYH1_k127_6775082_8 Bacterial regulatory proteins, tetR family - - - 0.0000000002107 69.0
PYH1_k127_6775082_9 - - - - 0.0008414 52.0
PYH1_k127_6805036_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.421e-196 624.0
PYH1_k127_6805036_1 lipopolysaccharide transport K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 390.0
PYH1_k127_6805036_10 - - - - 0.0000000000000006475 88.0
PYH1_k127_6805036_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001608 74.0
PYH1_k127_6805036_12 Protein conserved in bacteria - - - 0.00001707 58.0
PYH1_k127_6805036_13 FecR protein - - - 0.00004337 55.0
PYH1_k127_6805036_2 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 325.0
PYH1_k127_6805036_3 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 322.0
PYH1_k127_6805036_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 315.0
PYH1_k127_6805036_5 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 317.0
PYH1_k127_6805036_6 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000001964 231.0
PYH1_k127_6805036_7 - - - - 0.0000000000000000000000000000000000000000000000002298 186.0
PYH1_k127_6805036_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0032991,GO:0032993,GO:0043565,GO:0097159,GO:1901363 3.4.21.88 0.0000000000000000000000000000000000000000000153 169.0
PYH1_k127_6805036_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000005139 166.0
PYH1_k127_6827296_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.835e-217 686.0
PYH1_k127_6827296_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 486.0
PYH1_k127_6827296_10 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.0000000000000000000000000000000000000000000000000000000006017 209.0
PYH1_k127_6827296_11 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000006157 202.0
PYH1_k127_6827296_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000006819 211.0
PYH1_k127_6827296_13 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000007469 196.0
PYH1_k127_6827296_14 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000001336 191.0
PYH1_k127_6827296_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000002458 101.0
PYH1_k127_6827296_16 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000004973 93.0
PYH1_k127_6827296_2 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 478.0
PYH1_k127_6827296_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 447.0
PYH1_k127_6827296_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 379.0
PYH1_k127_6827296_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 349.0
PYH1_k127_6827296_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 332.0
PYH1_k127_6827296_7 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 296.0
PYH1_k127_6827296_8 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K11707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005276 249.0
PYH1_k127_6827296_9 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000005428 237.0
PYH1_k127_6833078_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 327.0
PYH1_k127_6833078_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006707 250.0
PYH1_k127_6833078_2 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000007325 246.0
PYH1_k127_6833078_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000002579 224.0
PYH1_k127_6833078_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000005815 97.0
PYH1_k127_6833078_5 Glycine-zipper domain - - - 0.00000000000006151 72.0
PYH1_k127_6833078_6 - - - - 0.000000000002235 74.0
PYH1_k127_6838287_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 423.0
PYH1_k127_6838287_1 Membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 310.0
PYH1_k127_6838287_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 299.0
PYH1_k127_6838287_3 - - - - 0.0000000000000000000000000000000000000000001411 165.0
PYH1_k127_6838287_4 - - - - 0.0000000000000000000000000000000000000003406 152.0
PYH1_k127_6838287_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000004965 54.0
PYH1_k127_6861544_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 5.275e-195 619.0
PYH1_k127_6861544_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 475.0
PYH1_k127_6861544_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 318.0
PYH1_k127_6861544_3 PFAM Radical SAM K04069 - 1.97.1.4 0.00000377 49.0
PYH1_k127_6868756_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 9.834e-267 830.0
PYH1_k127_6868756_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 473.0
PYH1_k127_6868756_2 rRNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000546 217.0
PYH1_k127_6868756_3 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000003713 209.0
PYH1_k127_687942_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 411.0
PYH1_k127_687942_1 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000268 173.0
PYH1_k127_687942_2 Glycine-zipper domain - - - 0.00001269 52.0
PYH1_k127_6894203_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 629.0
PYH1_k127_6894203_10 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 292.0
PYH1_k127_6894203_11 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 288.0
PYH1_k127_6894203_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005848 284.0
PYH1_k127_6894203_13 Luciferase-like monooxygenase K00320,K14728 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004259 261.0
PYH1_k127_6894203_14 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000003228 221.0
PYH1_k127_6894203_15 Sugar (and other) transporter K08161 - - 0.00000000000000000000000000000000000000000006488 178.0
PYH1_k127_6894203_16 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000005792 149.0
PYH1_k127_6894203_17 - - - - 0.000000000000000000000007884 108.0
PYH1_k127_6894203_18 - - - - 0.0000000000000000000001105 99.0
PYH1_k127_6894203_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000271 98.0
PYH1_k127_6894203_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 486.0
PYH1_k127_6894203_20 Histidine kinase - - - 0.0000000000000000006842 92.0
PYH1_k127_6894203_21 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.0000000003696 65.0
PYH1_k127_6894203_22 ATP-independent chaperone mediated protein folding - - - 0.0002437 51.0
PYH1_k127_6894203_3 MacB-like periplasmic core domain K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 466.0
PYH1_k127_6894203_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 453.0
PYH1_k127_6894203_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 428.0
PYH1_k127_6894203_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 385.0
PYH1_k127_6894203_7 Serine aminopeptidase, S33 - GO:0003674,GO:0003824,GO:0004301,GO:0005488,GO:0005515,GO:0016787,GO:0016801,GO:0016803,GO:0018742,GO:0042802,GO:0042803,GO:0046983 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 388.0
PYH1_k127_6894203_8 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 348.0
PYH1_k127_6894203_9 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 324.0
PYH1_k127_689756_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 450.0
PYH1_k127_689756_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 384.0
PYH1_k127_6899898_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 1.358e-310 970.0
PYH1_k127_6899898_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 639.0
PYH1_k127_6899898_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 326.0
PYH1_k127_6899898_11 tRNA processing K06864,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 323.0
PYH1_k127_6899898_12 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 313.0
PYH1_k127_6899898_13 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 304.0
PYH1_k127_6899898_14 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004539 278.0
PYH1_k127_6899898_15 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001693 266.0
PYH1_k127_6899898_16 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 235.0
PYH1_k127_6899898_17 'Molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000000000489 226.0
PYH1_k127_6899898_18 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000111 215.0
PYH1_k127_6899898_19 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000007551 160.0
PYH1_k127_6899898_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 463.0
PYH1_k127_6899898_20 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000006129 149.0
PYH1_k127_6899898_21 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000001373 136.0
PYH1_k127_6899898_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14751 - - 0.00000000000000000000000000000002697 134.0
PYH1_k127_6899898_23 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000001316 123.0
PYH1_k127_6899898_24 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000452 109.0
PYH1_k127_6899898_25 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0001056 49.0
PYH1_k127_6899898_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 398.0
PYH1_k127_6899898_4 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 381.0
PYH1_k127_6899898_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 371.0
PYH1_k127_6899898_6 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 361.0
PYH1_k127_6899898_7 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 340.0
PYH1_k127_6899898_8 SMART Elongator protein 3 MiaB NifB K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 337.0
PYH1_k127_6899898_9 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 331.0
PYH1_k127_693198_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 610.0
PYH1_k127_693198_1 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 347.0
PYH1_k127_693198_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001158 192.0
PYH1_k127_693198_3 Tautomerase enzyme - - - 0.00000000003235 68.0
PYH1_k127_693198_4 Dihydroorotate dehydrogenase - - - 0.00000000004211 70.0
PYH1_k127_693198_5 FecR protein - - - 0.0006915 53.0
PYH1_k127_6945270_0 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 591.0
PYH1_k127_6945270_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 376.0
PYH1_k127_6945270_2 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003457 270.0
PYH1_k127_6945270_3 alpha/beta hydrolase fold K14731 - 3.1.1.83 0.000000000000007223 80.0
PYH1_k127_6945270_4 PIN domain - - - 0.00000000000002464 77.0
PYH1_k127_6945270_5 MlaA lipoprotein K04754 - - 0.00000000002657 69.0
PYH1_k127_6945270_7 Transposase IS116/IS110/IS902 family - - - 0.0008741 42.0
PYH1_k127_6948617_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 417.0
PYH1_k127_6948617_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 424.0
PYH1_k127_6948617_2 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007265 282.0
PYH1_k127_6948617_3 GntR family transcriptional regulator K03486,K03710 - - 0.000000000000000000000000003473 117.0
PYH1_k127_6948617_4 pfam abc K01995 - - 0.000000000000000000000000003539 113.0
PYH1_k127_7002834_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 2.958e-265 827.0
PYH1_k127_7002834_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 442.0
PYH1_k127_7002834_10 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000003076 181.0
PYH1_k127_7002834_11 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000009526 164.0
PYH1_k127_7002834_12 MaoC like domain - - - 0.0000000000000000000000000000000000000003029 154.0
PYH1_k127_7002834_13 dehydratase - - - 0.000000000005501 77.0
PYH1_k127_7002834_2 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 417.0
PYH1_k127_7002834_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 366.0
PYH1_k127_7002834_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
PYH1_k127_7002834_5 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 373.0
PYH1_k127_7002834_6 ABC-type sugar K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 329.0
PYH1_k127_7002834_7 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 309.0
PYH1_k127_7002834_8 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
PYH1_k127_7002834_9 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000108 228.0
PYH1_k127_7008061_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 2.968e-252 794.0
PYH1_k127_7008061_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 477.0
PYH1_k127_7008061_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 342.0
PYH1_k127_7008061_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000004625 172.0
PYH1_k127_7008061_4 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001098 82.0
PYH1_k127_7034915_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.59e-206 661.0
PYH1_k127_7034915_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 567.0
PYH1_k127_7034915_2 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 495.0
PYH1_k127_7034915_3 Malate synthase K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000004154 238.0
PYH1_k127_7034915_4 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000001356 151.0
PYH1_k127_7048200_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 467.0
PYH1_k127_7048200_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 389.0
PYH1_k127_7048200_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000005809 210.0
PYH1_k127_7048200_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000006649 156.0
PYH1_k127_7048200_4 mandelate racemase muconate lactonizing K01781 - 5.1.2.2 0.000000000000006841 86.0
PYH1_k127_7057814_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.632e-196 629.0
PYH1_k127_7057814_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 593.0
PYH1_k127_7057814_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 410.0
PYH1_k127_7057814_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000002894 198.0
PYH1_k127_7057814_4 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000009896 150.0
PYH1_k127_7057814_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000002161 143.0
PYH1_k127_7057814_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00001153 49.0
PYH1_k127_7113503_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 338.0
PYH1_k127_7113503_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000003541 125.0
PYH1_k127_7113503_2 Evidence 5 No homology to any previously reported sequences K03765 - - 0.0000000000000000000001101 114.0
PYH1_k127_7118540_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 448.0
PYH1_k127_7118540_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 311.0
PYH1_k127_7118540_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 309.0
PYH1_k127_7118540_3 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000001881 154.0
PYH1_k127_7118540_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000001494 145.0
PYH1_k127_7118540_5 Glycosyl transferase, family 2 K07011,K20444 - - 0.0000000000000000000000001431 117.0
PYH1_k127_7118540_6 - - - - 0.00000000000000000000006537 111.0
PYH1_k127_7118540_7 Mycolic acid cyclopropane synthetase - - - 0.000000005031 60.0
PYH1_k127_7119922_0 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 528.0
PYH1_k127_7119922_1 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 430.0
PYH1_k127_7119922_2 LUD domain K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 385.0
PYH1_k127_7119922_3 Cysteine-rich domain protein K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000513 267.0
PYH1_k127_7119922_4 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001253 259.0
PYH1_k127_7119922_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000005918 107.0
PYH1_k127_7135759_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 7.328e-218 703.0
PYH1_k127_7135759_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 395.0
PYH1_k127_7135759_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001693 258.0
PYH1_k127_7135759_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000002664 250.0
PYH1_k127_7135759_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000262 222.0
PYH1_k127_7135759_5 GYD domain - - - 0.00000000000000000000000000000006543 131.0
PYH1_k127_7135759_6 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000001227 130.0
PYH1_k127_7135759_7 Universal stress protein family - - - 0.000000000000000000000004521 109.0
PYH1_k127_7135759_8 translation release factor activity K03265 - - 0.000005002 50.0
PYH1_k127_7141223_0 Thiamine pyrophosphate enzyme, central domain - - - 9.454e-248 808.0
PYH1_k127_7141223_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 3.69e-245 800.0
PYH1_k127_7141223_2 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 495.0
PYH1_k127_7141223_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
PYH1_k127_7141223_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 347.0
PYH1_k127_7141223_5 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009099 290.0
PYH1_k127_7141223_6 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000000000001822 175.0
PYH1_k127_7141223_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000003392 94.0
PYH1_k127_7141223_8 DinB superfamily - - - 0.00000000000005291 84.0
PYH1_k127_7144383_0 Circularly permuted ATP-grasp type 2 - - - 1.419e-214 686.0
PYH1_k127_7144383_1 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 2.335e-197 628.0
PYH1_k127_7144383_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 269.0
PYH1_k127_7144383_11 cellular water homeostasis K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
PYH1_k127_7144383_12 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003626 251.0
PYH1_k127_7144383_13 Receptor family ligand binding region family protein 22 K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004655 269.0
PYH1_k127_7144383_14 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000001154 203.0
PYH1_k127_7144383_15 PFAM NUDIX domain - - - 0.00000000000000000000000000000000000000000000003797 175.0
PYH1_k127_7144383_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002374 175.0
PYH1_k127_7144383_17 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000003117 164.0
PYH1_k127_7144383_18 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000001244 163.0
PYH1_k127_7144383_19 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000002567 143.0
PYH1_k127_7144383_2 Peptidase dimerisation domain K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 402.0
PYH1_k127_7144383_20 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000004442 134.0
PYH1_k127_7144383_21 Thioesterase family - - - 0.00000000000000000000000000000004195 129.0
PYH1_k127_7144383_22 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000363 124.0
PYH1_k127_7144383_23 - - - - 0.0000000000000192 75.0
PYH1_k127_7144383_24 - - - - 0.0000001274 62.0
PYH1_k127_7144383_25 - - - - 0.0009538 45.0
PYH1_k127_7144383_3 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 394.0
PYH1_k127_7144383_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 348.0
PYH1_k127_7144383_5 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 306.0
PYH1_k127_7144383_6 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
PYH1_k127_7144383_7 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001622 289.0
PYH1_k127_7144383_8 Abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004382 269.0
PYH1_k127_7144383_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 273.0
PYH1_k127_7186364_0 Adenylate and Guanylate cyclase catalytic domain - - - 1.6e-322 1024.0
PYH1_k127_7186364_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000005469 204.0
PYH1_k127_7186364_2 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000004732 121.0
PYH1_k127_7186364_3 - - - - 0.0000000001879 67.0
PYH1_k127_7305843_0 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 350.0
PYH1_k127_7305843_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 325.0
PYH1_k127_7305843_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 289.0
PYH1_k127_7305843_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000001056 218.0
PYH1_k127_7305843_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000001186 161.0
PYH1_k127_7305843_5 - - - - 0.0000000000000000001808 93.0
PYH1_k127_7305843_6 Belongs to the ompA family K03286 - - 0.000000001515 67.0
PYH1_k127_7305843_7 redox protein, regulator of disulfide bond formation K07397 - - 0.000004035 51.0
PYH1_k127_7305843_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0002091 50.0
PYH1_k127_7305843_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0006783 51.0
PYH1_k127_7306857_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1678.0
PYH1_k127_7306857_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 7.009e-211 659.0
PYH1_k127_7306857_2 chaperone-mediated protein complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 312.0
PYH1_k127_7306857_3 Pas domain - - - 0.00000000000000000000000000000000000000000000004415 177.0
PYH1_k127_7307996_0 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 359.0
PYH1_k127_7307996_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000006199 245.0
PYH1_k127_733749_0 GTP-binding protein TypA K06207 - - 6.81e-262 824.0
PYH1_k127_733749_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.09e-207 670.0
PYH1_k127_733749_10 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000002352 243.0
PYH1_k127_733749_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001607 217.0
PYH1_k127_733749_12 TIGRFAM molybdate ABC transporter, inner membrane subunit K02018 - - 0.0000000000000000000000000000000000000000000000000007104 193.0
PYH1_k127_733749_13 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000001035 195.0
PYH1_k127_733749_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000369 188.0
PYH1_k127_733749_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000003457 181.0
PYH1_k127_733749_16 PFAM regulatory protein, LysR K02019 - - 0.000000000000001048 83.0
PYH1_k127_733749_17 - K09794 - - 0.0000007615 54.0
PYH1_k127_733749_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 496.0
PYH1_k127_733749_3 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 471.0
PYH1_k127_733749_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 440.0
PYH1_k127_733749_5 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 359.0
PYH1_k127_733749_6 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 355.0
PYH1_k127_733749_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 347.0
PYH1_k127_733749_8 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 315.0
PYH1_k127_733749_9 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 301.0
PYH1_k127_7365439_0 acetyl-coa acetyltransferase - - - 8.703e-210 656.0
PYH1_k127_7365439_1 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 466.0
PYH1_k127_7365439_2 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 429.0
PYH1_k127_7365439_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00018 - 1.1.1.26,1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 422.0
PYH1_k127_7365439_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 248.0
PYH1_k127_7365439_5 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000005045 201.0
PYH1_k127_7365439_6 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000008675 207.0
PYH1_k127_739178_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.026e-261 826.0
PYH1_k127_739178_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 1.345e-197 627.0
PYH1_k127_739178_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000003612 88.0
PYH1_k127_739178_11 O-linked GlcNAc transferase - - - 0.0000004035 58.0
PYH1_k127_739178_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 563.0
PYH1_k127_739178_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 538.0
PYH1_k127_739178_4 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 399.0
PYH1_k127_739178_5 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 395.0
PYH1_k127_739178_6 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 396.0
PYH1_k127_739178_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
PYH1_k127_739178_8 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 302.0
PYH1_k127_739178_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000495 255.0
PYH1_k127_7400131_0 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 1.43e-201 644.0
PYH1_k127_7400131_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000004862 226.0
PYH1_k127_7400131_2 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000001675 72.0
PYH1_k127_7421537_0 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 399.0
PYH1_k127_7421537_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000004945 194.0
PYH1_k127_7421537_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000144 126.0
PYH1_k127_7455242_0 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 4.143e-237 760.0
PYH1_k127_7455242_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 468.0
PYH1_k127_7455242_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000003278 164.0
PYH1_k127_7455242_11 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000001042 155.0
PYH1_k127_7455242_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000003712 147.0
PYH1_k127_7455242_13 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000002694 132.0
PYH1_k127_7455242_14 Cupredoxin-like domain - - - 0.0000000000000000002024 92.0
PYH1_k127_7455242_15 PFAM YCII-related domain K09780 - - 0.0000000004681 68.0
PYH1_k127_7455242_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00002083 47.0
PYH1_k127_7455242_2 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 451.0
PYH1_k127_7455242_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 440.0
PYH1_k127_7455242_4 Serine hydrolase (FSH1) K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003345 276.0
PYH1_k127_7455242_5 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005235 261.0
PYH1_k127_7455242_6 Inositol monophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001026 244.0
PYH1_k127_7455242_7 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
PYH1_k127_7455242_8 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000008949 199.0
PYH1_k127_7455242_9 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000006378 172.0
PYH1_k127_7489679_0 4-hydroxyphenylacetate K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 520.0
PYH1_k127_7489679_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 406.0
PYH1_k127_7489679_10 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001395 285.0
PYH1_k127_7489679_11 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002148 278.0
PYH1_k127_7489679_12 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000009387 263.0
PYH1_k127_7489679_13 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002413 268.0
PYH1_k127_7489679_14 Belongs to the enoyl-CoA hydratase isomerase family K07546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002682 254.0
PYH1_k127_7489679_15 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000005926 216.0
PYH1_k127_7489679_16 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000004924 220.0
PYH1_k127_7489679_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000008455 207.0
PYH1_k127_7489679_18 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001727 203.0
PYH1_k127_7489679_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000004186 205.0
PYH1_k127_7489679_2 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 402.0
PYH1_k127_7489679_20 Fumarylacetoacetate (FAA) hydrolase family K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000001411 193.0
PYH1_k127_7489679_21 NUDIX domain - - - 0.00000000000000000000000000001042 129.0
PYH1_k127_7489679_22 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000004888 95.0
PYH1_k127_7489679_23 Cytochrome C' - - - 0.000000000000991 80.0
PYH1_k127_7489679_24 iron ion homeostasis - - - 0.0000002768 61.0
PYH1_k127_7489679_3 branched-chain amino acid transport system, permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 407.0
PYH1_k127_7489679_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 388.0
PYH1_k127_7489679_5 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 345.0
PYH1_k127_7489679_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
PYH1_k127_7489679_7 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 317.0
PYH1_k127_7489679_8 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 310.0
PYH1_k127_7489679_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
PYH1_k127_7520682_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 1.296e-286 890.0
PYH1_k127_7520682_1 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 2.748e-283 895.0
PYH1_k127_7520682_10 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 322.0
PYH1_k127_7520682_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 328.0
PYH1_k127_7520682_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004401 275.0
PYH1_k127_7520682_13 ATPases associated with a variety of cellular activities K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001552 272.0
PYH1_k127_7520682_14 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001661 271.0
PYH1_k127_7520682_15 PFAM Urease beta subunit K01429,K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000000000592 171.0
PYH1_k127_7520682_16 Urease, gamma subunit - - - 0.0000000000000000000000000000000000000000000002604 168.0
PYH1_k127_7520682_17 TIGRFAM urea ABC transporter, ATP-binding protein UrtD K11962 - - 0.00000000000000000000000000000000000000000123 158.0
PYH1_k127_7520682_18 Protein of unknown function (DUF3225) - - - 0.00000000000000000000000000000000000000001679 163.0
PYH1_k127_7520682_19 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000002685 157.0
PYH1_k127_7520682_2 phosphate transport system permease protein K02038 - - 1.233e-207 666.0
PYH1_k127_7520682_20 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000002283 147.0
PYH1_k127_7520682_21 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000001516 126.0
PYH1_k127_7520682_22 nickel cation binding K03190 - - 0.000000000000000000000000006926 121.0
PYH1_k127_7520682_23 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000003394 111.0
PYH1_k127_7520682_24 EamA-like transporter family - - - 0.0000000000000000000000003597 116.0
PYH1_k127_7520682_25 PFAM response regulator receiver K07657 - - 0.00000000000000000004538 95.0
PYH1_k127_7520682_26 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000578 75.0
PYH1_k127_7520682_27 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000002333 70.0
PYH1_k127_7520682_28 Protein of unknown function (DUF4089) - - - 0.00000731 51.0
PYH1_k127_7520682_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.335e-200 646.0
PYH1_k127_7520682_4 NAD synthase K01916 - 6.3.1.5 1.221e-195 625.0
PYH1_k127_7520682_5 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 602.0
PYH1_k127_7520682_6 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 561.0
PYH1_k127_7520682_7 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 497.0
PYH1_k127_7520682_8 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 430.0
PYH1_k127_7520682_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 385.0
PYH1_k127_7524354_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 316.0
PYH1_k127_7524354_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 303.0
PYH1_k127_7524354_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006899 276.0
PYH1_k127_7524354_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004107 250.0
PYH1_k127_7524354_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02337,K02342,K03654 - 2.7.7.7,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000259 218.0
PYH1_k127_7524354_5 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000005638 157.0
PYH1_k127_7524354_6 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000005912 112.0
PYH1_k127_7549261_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.962e-201 637.0
PYH1_k127_7549261_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 431.0
PYH1_k127_7549261_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000004346 176.0
PYH1_k127_7549261_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000006662 146.0
PYH1_k127_7549261_4 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000001333 105.0
PYH1_k127_7549261_5 Universal stress protein - - - 0.000000000000000000006202 101.0
PYH1_k127_7549261_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000002179 93.0
PYH1_k127_7549261_7 Cbs domain K04767 - - 0.00000000000000009918 85.0
PYH1_k127_7549261_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000006284 72.0
PYH1_k127_7549261_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000001323 57.0
PYH1_k127_7594982_0 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 363.0
PYH1_k127_7594982_1 hydrolase of alkaline phosphatase superfamily K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 368.0
PYH1_k127_7594982_10 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000006656 248.0
PYH1_k127_7594982_11 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001406 229.0
PYH1_k127_7594982_12 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000002924 227.0
PYH1_k127_7594982_13 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000006366 193.0
PYH1_k127_7594982_14 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.0000000000000000000000000000000000000000000000001524 198.0
PYH1_k127_7594982_15 KR domain - - - 0.000000000000000000000000000000000000000000000006377 181.0
PYH1_k127_7594982_16 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000638 184.0
PYH1_k127_7594982_17 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000001306 176.0
PYH1_k127_7594982_18 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000001415 178.0
PYH1_k127_7594982_19 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000003896 151.0
PYH1_k127_7594982_2 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 346.0
PYH1_k127_7594982_20 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000001832 136.0
PYH1_k127_7594982_21 60Kd inner membrane protein - - - 0.000000000000000000000000000000001226 148.0
PYH1_k127_7594982_22 - - - - 0.00000000000000008691 83.0
PYH1_k127_7594982_23 Protein of unknown function (DUF429) - - - 0.00000000000001656 87.0
PYH1_k127_7594982_3 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
PYH1_k127_7594982_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001978 283.0
PYH1_k127_7594982_5 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003665 272.0
PYH1_k127_7594982_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005062 263.0
PYH1_k127_7594982_7 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 252.0
PYH1_k127_7594982_8 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001191 256.0
PYH1_k127_7594982_9 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000002511 246.0
PYH1_k127_7624424_0 Protein of unknown function (DUF3141) - - - 8e-323 1012.0
PYH1_k127_7624424_1 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 560.0
PYH1_k127_7624424_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 526.0
PYH1_k127_7624424_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000009509 216.0
PYH1_k127_7624424_4 - - - - 0.0000000000000000000001122 106.0
PYH1_k127_7624424_5 Electron transfer flavoprotein K03521 - - 0.00000005591 64.0
PYH1_k127_7624424_6 FAD binding domain K21401 - 1.3.99.38 0.0007492 53.0
PYH1_k127_7626438_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 1.913e-269 858.0
PYH1_k127_7626438_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.206e-211 665.0
PYH1_k127_7626438_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 476.0
PYH1_k127_7626438_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 436.0
PYH1_k127_7626438_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 441.0
PYH1_k127_7626438_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000007402 263.0
PYH1_k127_7626438_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000001052 214.0
PYH1_k127_7626438_7 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000000000000005889 111.0
PYH1_k127_7626438_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000007107 123.0
PYH1_k127_7626438_9 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000001603 76.0
PYH1_k127_7628495_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 477.0
PYH1_k127_7628495_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 463.0
PYH1_k127_7628495_10 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000899 226.0
PYH1_k127_7628495_11 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000004558 212.0
PYH1_k127_7628495_12 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000001772 210.0
PYH1_k127_7628495_13 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000001063 187.0
PYH1_k127_7628495_14 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000297 147.0
PYH1_k127_7628495_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000001411 133.0
PYH1_k127_7628495_16 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000006525 137.0
PYH1_k127_7628495_17 Carboxymuconolactone decarboxylase family - - - 0.00000000000001061 77.0
PYH1_k127_7628495_18 Carboxymuconolactone decarboxylase family - - - 0.0001322 50.0
PYH1_k127_7628495_2 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 353.0
PYH1_k127_7628495_3 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 313.0
PYH1_k127_7628495_4 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002987 274.0
PYH1_k127_7628495_5 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
PYH1_k127_7628495_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003199 264.0
PYH1_k127_7628495_7 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008925 263.0
PYH1_k127_7628495_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000007655 234.0
PYH1_k127_7628495_9 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000001032 248.0
PYH1_k127_7648487_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 348.0
PYH1_k127_7648487_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000245 275.0
PYH1_k127_7655646_0 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 568.0
PYH1_k127_7655646_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 460.0
PYH1_k127_7655646_2 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000001066 260.0
PYH1_k127_7655646_3 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000002484 196.0
PYH1_k127_7655646_4 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000009139 166.0
PYH1_k127_7655646_5 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000003607 75.0
PYH1_k127_7655646_6 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000001987 77.0
PYH1_k127_7655646_7 PFAM transport-associated K04065 - - 0.00000000447 64.0
PYH1_k127_7724382_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 4.487e-249 782.0
PYH1_k127_7724382_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 448.0
PYH1_k127_7724382_2 - - - - 0.00000000000000000000001062 103.0
PYH1_k127_7724382_3 Transmembrane secretion effector - - - 0.000000000000000001129 89.0
PYH1_k127_7732770_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 5.761e-230 721.0
PYH1_k127_7732770_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 563.0
PYH1_k127_7732770_10 ATP-binding region ATPase domain protein - - - 0.00000000007166 74.0
PYH1_k127_7732770_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 524.0
PYH1_k127_7732770_3 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000105 284.0
PYH1_k127_7732770_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
PYH1_k127_7732770_5 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 253.0
PYH1_k127_7732770_6 Copper/zinc superoxide dismutase (SODC) - - - 0.0000000000000000000000000000000000000000001808 168.0
PYH1_k127_7732770_7 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000001732 154.0
PYH1_k127_7732770_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000001903 144.0
PYH1_k127_7732770_9 Putative restriction endonuclease - - - 0.00000000000004796 83.0
PYH1_k127_7733860_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 408.0
PYH1_k127_7733860_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 383.0
PYH1_k127_7733860_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 369.0
PYH1_k127_7733860_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 311.0
PYH1_k127_7733860_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000002289 222.0
PYH1_k127_7733860_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000002158 142.0
PYH1_k127_7733860_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000442 142.0
PYH1_k127_7733860_7 Protein of unknown function (DUF721) - - - 0.0000001527 60.0
PYH1_k127_7733860_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00005225 54.0
PYH1_k127_7737743_0 Type II/IV secretion system protein K02652,K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 410.0
PYH1_k127_7737743_1 Acyl-CoA dehydrogenase, C-terminal domain K19966 - 3.13.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 402.0
PYH1_k127_7737743_10 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000001043 105.0
PYH1_k127_7737743_11 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000001706 97.0
PYH1_k127_7737743_12 methyltransferase - - - 0.00000005813 64.0
PYH1_k127_7737743_13 Prelipin peptidase dependent protein K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0006604 49.0
PYH1_k127_7737743_14 Prelipin peptidase dependent protein K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000752 48.0
PYH1_k127_7737743_2 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 353.0
PYH1_k127_7737743_3 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 333.0
PYH1_k127_7737743_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 318.0
PYH1_k127_7737743_5 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000001444 256.0
PYH1_k127_7737743_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000005272 249.0
PYH1_k127_7737743_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000007757 250.0
PYH1_k127_7737743_8 Cytidylate kinase-like family - - - 0.00000000000000000000000000000003964 136.0
PYH1_k127_7744806_0 Helicase - - - 7.458e-318 997.0
PYH1_k127_7744806_1 Gamma-glutamyltranspeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 583.0
PYH1_k127_7744806_10 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009538 261.0
PYH1_k127_7744806_11 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
PYH1_k127_7744806_12 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000002522 210.0
PYH1_k127_7744806_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000000000000000000007182 212.0
PYH1_k127_7744806_14 metallo-beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000006524 212.0
PYH1_k127_7744806_15 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000009993 198.0
PYH1_k127_7744806_16 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000001627 124.0
PYH1_k127_7744806_17 Thioesterase superfamily K01075 - 3.1.2.23 0.00000000000000000000000008366 111.0
PYH1_k127_7744806_18 - - - - 0.0000000000000000001643 97.0
PYH1_k127_7744806_19 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.0000000000003611 76.0
PYH1_k127_7744806_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 453.0
PYH1_k127_7744806_3 AMP-binding enzyme K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 407.0
PYH1_k127_7744806_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 356.0
PYH1_k127_7744806_5 Ethanolamine utilization protein EutJ K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 328.0
PYH1_k127_7744806_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 336.0
PYH1_k127_7744806_7 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 297.0
PYH1_k127_7744806_8 PFAM SWIM zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
PYH1_k127_7744806_9 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003823 265.0
PYH1_k127_7746041_0 4Fe-4S dicluster domain K00184 - - 3.305e-211 692.0
PYH1_k127_7746041_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 550.0
PYH1_k127_7746041_10 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000001391 194.0
PYH1_k127_7746041_11 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000001896 160.0
PYH1_k127_7746041_12 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000002475 138.0
PYH1_k127_7746041_13 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000005432 127.0
PYH1_k127_7746041_14 Transcriptional regulator - - - 0.000000000000000000000002026 109.0
PYH1_k127_7746041_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000003129 111.0
PYH1_k127_7746041_16 ThiF family K03148,K03636,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000001851 99.0
PYH1_k127_7746041_17 Necessary for formate dehydrogenase activity K02380 - - 0.0000003307 54.0
PYH1_k127_7746041_2 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
PYH1_k127_7746041_3 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 509.0
PYH1_k127_7746041_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 438.0
PYH1_k127_7746041_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 376.0
PYH1_k127_7746041_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 340.0
PYH1_k127_7746041_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 278.0
PYH1_k127_7746041_8 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000002562 229.0
PYH1_k127_7746041_9 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000001327 207.0
PYH1_k127_7780987_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 2.905e-199 640.0
PYH1_k127_7780987_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 394.0
PYH1_k127_7780987_2 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
PYH1_k127_7780987_3 Binding-protein-dependent transport system inner membrane component K02025,K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001241 253.0
PYH1_k127_7780987_4 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000001005 212.0
PYH1_k127_7780987_5 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000006489 192.0
PYH1_k127_7780987_6 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000006461 186.0
PYH1_k127_7780987_7 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000001561 99.0
PYH1_k127_7780987_8 ABC transporter substrate-binding protein K02027 - - 0.0000000000000005695 84.0
PYH1_k127_7797024_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 315.0
PYH1_k127_7797024_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001814 275.0
PYH1_k127_7797024_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000008843 53.0
PYH1_k127_784004_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 7.322e-216 685.0
PYH1_k127_784004_1 Belongs to the CinA family - - - 2.618e-203 641.0
PYH1_k127_784004_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 228.0
PYH1_k127_784004_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000186 226.0
PYH1_k127_784004_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000001216 195.0
PYH1_k127_784004_5 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000000000000000000000002396 112.0
PYH1_k127_7868659_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003744 281.0
PYH1_k127_7868659_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000001028 158.0
PYH1_k127_7868659_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000001309 105.0
PYH1_k127_7868659_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000001761 89.0
PYH1_k127_7892040_0 Aconitase family (aconitate hydratase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 411.0
PYH1_k127_7892040_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001077 258.0
PYH1_k127_7892040_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K12369,K19227 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000004589 139.0
PYH1_k127_7908027_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 406.0
PYH1_k127_7908027_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001689 281.0
PYH1_k127_7908027_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000005996 205.0
PYH1_k127_7908027_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000006884 108.0
PYH1_k127_7908027_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000001117 76.0
PYH1_k127_7908027_5 dmso reductase anchor subunit K18363 - - 0.00000004599 63.0
PYH1_k127_7911606_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 9.083e-220 689.0
PYH1_k127_7911606_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 395.0
PYH1_k127_7915524_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 3.827e-215 683.0
PYH1_k127_7915524_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 404.0
PYH1_k127_7915524_10 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000000002172 212.0
PYH1_k127_7915524_11 Cytidylate kinase K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000004952 209.0
PYH1_k127_7915524_12 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000007675 214.0
PYH1_k127_7915524_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000001138 179.0
PYH1_k127_7915524_14 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000003865 179.0
PYH1_k127_7915524_15 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000006949 180.0
PYH1_k127_7915524_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000002742 158.0
PYH1_k127_7915524_17 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000001441 154.0
PYH1_k127_7915524_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000006243 145.0
PYH1_k127_7915524_19 regulation of translation K05788 - - 0.000000000000000000000000000000008731 130.0
PYH1_k127_7915524_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 396.0
PYH1_k127_7915524_3 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 392.0
PYH1_k127_7915524_4 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 278.0
PYH1_k127_7915524_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007195 268.0
PYH1_k127_7915524_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000004274 273.0
PYH1_k127_7915524_7 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
PYH1_k127_7915524_8 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000006844 225.0
PYH1_k127_7915524_9 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000002813 221.0
PYH1_k127_7927474_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002388 292.0
PYH1_k127_7927474_1 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.00000000000000000000000000000000000000001297 161.0
PYH1_k127_7927474_2 Domain in cystathionine beta-synthase and other proteins. K02000 - 3.6.3.32 0.00000006309 59.0
PYH1_k127_7950661_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.877e-236 746.0
PYH1_k127_7950661_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 423.0
PYH1_k127_7950661_2 domain protein - - - 0.000000000000000000000000000000000000000000000000000006528 200.0
PYH1_k127_7950661_3 - - - - 0.00000000000000000000000002963 117.0
PYH1_k127_7968224_0 PFAM Sodium sulphate symporter K03319,K11106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 545.0
PYH1_k127_7968224_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 442.0
PYH1_k127_7968224_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 325.0
PYH1_k127_7968224_3 aryl-alcohol dehydrogenase (NAD+) activity K00055 - 1.1.1.90 0.000000000000000005795 84.0
PYH1_k127_7968224_4 Integral membrane protein TerC family - - - 0.00001801 51.0
PYH1_k127_7970396_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.073e-214 682.0
PYH1_k127_7970396_1 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 400.0
PYH1_k127_7970396_2 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
PYH1_k127_7970396_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000002458 183.0
PYH1_k127_7970396_4 protein, possibly involved in aromatic compounds catabolism - - - 0.000002938 59.0
PYH1_k127_8004046_0 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 378.0
PYH1_k127_8004046_1 Protein involved in propionate catabolism - - - 0.00000000000000000000000000000000000000000000000000000005797 205.0
PYH1_k127_8004046_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000006933 147.0
PYH1_k127_8004046_3 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000003257 64.0
PYH1_k127_8034246_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 1.414e-240 766.0
PYH1_k127_8034246_1 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 601.0
PYH1_k127_8034246_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 503.0
PYH1_k127_8034246_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 466.0
PYH1_k127_8034246_4 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 433.0
PYH1_k127_8034246_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 378.0
PYH1_k127_8034246_6 Gaf domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 366.0
PYH1_k127_8034246_7 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000003975 135.0
PYH1_k127_8034246_8 Adenylate and Guanylate cyclase catalytic domain - - - 0.00005941 48.0
PYH1_k127_8065347_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 522.0
PYH1_k127_8065347_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 419.0
PYH1_k127_8065347_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000165 197.0
PYH1_k127_8065347_3 Cell division protein FtsQ K03589 - - 0.0000000000000001841 87.0
PYH1_k127_8091279_0 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 288.0
PYH1_k127_8091279_1 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000002253 139.0
PYH1_k127_8091279_2 Belongs to the UPF0312 family - - - 0.000002867 58.0
PYH1_k127_8129013_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.046e-278 871.0
PYH1_k127_8129013_1 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 3.093e-232 750.0
PYH1_k127_8129013_10 Trypsin-like serine protease K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007505 278.0
PYH1_k127_8129013_11 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004401 240.0
PYH1_k127_8129013_12 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000004321 199.0
PYH1_k127_8129013_13 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000004168 153.0
PYH1_k127_8129013_14 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K00697,K01087,K16055 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.00000000000000000000000000000000001135 148.0
PYH1_k127_8129013_15 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000003545 128.0
PYH1_k127_8129013_17 Histidine kinase K07647 - 2.7.13.3 0.0003955 50.0
PYH1_k127_8129013_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 560.0
PYH1_k127_8129013_3 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 529.0
PYH1_k127_8129013_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 473.0
PYH1_k127_8129013_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 473.0
PYH1_k127_8129013_6 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 451.0
PYH1_k127_8129013_7 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 422.0
PYH1_k127_8129013_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 385.0
PYH1_k127_8129013_9 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 372.0
PYH1_k127_8158826_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1006.0
PYH1_k127_8158826_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 4.135e-292 902.0
PYH1_k127_8158826_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000006885 195.0
PYH1_k127_8158826_11 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000004145 182.0
PYH1_k127_8158826_12 Cupin domain - - - 0.0000000000000000000000000000000000000008306 153.0
PYH1_k127_8158826_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000002189 91.0
PYH1_k127_8158826_14 - - - - 0.000000000001958 69.0
PYH1_k127_8158826_15 Glutaredoxin K03676,K06191 - - 0.00000002158 58.0
PYH1_k127_8158826_16 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00004705 51.0
PYH1_k127_8158826_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 524.0
PYH1_k127_8158826_3 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 490.0
PYH1_k127_8158826_4 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 365.0
PYH1_k127_8158826_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003142 253.0
PYH1_k127_8158826_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001467 259.0
PYH1_k127_8158826_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003079 252.0
PYH1_k127_8158826_8 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003684 235.0
PYH1_k127_8158826_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000001399 230.0
PYH1_k127_8162187_0 Two component signalling adaptor domain K02487,K06596 - - 0.0000000000000000000000000000000001355 136.0
PYH1_k127_8162187_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000316 141.0
PYH1_k127_8162187_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000001034 121.0
PYH1_k127_8170_0 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 398.0
PYH1_k127_8170_1 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 377.0
PYH1_k127_8170_2 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 313.0
PYH1_k127_8170_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 293.0
PYH1_k127_8170_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000001347 157.0
PYH1_k127_8170_5 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000006511 128.0
PYH1_k127_8170_6 - - - - 0.000000000000000001281 87.0
PYH1_k127_8170_7 - - - - 0.00000000000004092 82.0
PYH1_k127_8218957_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 484.0
PYH1_k127_8218957_1 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 426.0
PYH1_k127_8218957_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 399.0
PYH1_k127_8218957_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 337.0
PYH1_k127_8218957_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 302.0
PYH1_k127_8218957_5 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000004292 218.0
PYH1_k127_8218957_6 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000002549 193.0
PYH1_k127_8218957_7 CopC domain - - - 0.000000000000000000000000005419 123.0
PYH1_k127_8218957_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000001547 114.0
PYH1_k127_8218957_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000002891 117.0
PYH1_k127_8230032_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 512.0
PYH1_k127_8230032_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 419.0
PYH1_k127_8230032_2 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009124 257.0
PYH1_k127_8230032_3 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000005779 191.0
PYH1_k127_8230032_4 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000001519 181.0
PYH1_k127_8230032_5 Catalyzes the NAD-dependent oxidation of glucose 6- phosphate to 6-phosphogluconolactone K19243 - 1.1.1.388 0.0000000000000000000000000000000000000000000427 174.0
PYH1_k127_8230032_6 - - - - 0.0000000000000000000000000000000000002893 145.0
PYH1_k127_8272900_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 519.0
PYH1_k127_8272900_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 403.0
PYH1_k127_8272900_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009366 283.0
PYH1_k127_8272900_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000001258 238.0
PYH1_k127_8272900_4 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003307 244.0
PYH1_k127_8272900_5 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000004178 230.0
PYH1_k127_8273493_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 1.366e-265 839.0
PYH1_k127_8273493_1 AMP-dependent synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 379.0
PYH1_k127_8273493_2 Putative nucleotidyltransferase substrate binding domain - - - 0.000000000000000000000000009885 114.0
PYH1_k127_8273493_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000001566 105.0
PYH1_k127_8283536_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
PYH1_k127_8283536_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 372.0
PYH1_k127_8283536_10 Uncharacterized ACR, COG1399 K07040 - - 0.00006681 45.0
PYH1_k127_8283536_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 384.0
PYH1_k127_8283536_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 319.0
PYH1_k127_8283536_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 299.0
PYH1_k127_8283536_5 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000003592 271.0
PYH1_k127_8283536_6 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000531 155.0
PYH1_k127_8283536_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000002542 145.0
PYH1_k127_8283536_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000001536 113.0
PYH1_k127_8283536_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000002612 86.0
PYH1_k127_8288738_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 488.0
PYH1_k127_8288738_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 494.0
PYH1_k127_8288738_10 Cytochrome c7 and related cytochrome c - - - 0.0000000000006276 82.0
PYH1_k127_8288738_2 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
PYH1_k127_8288738_3 Taurine catabolism dioxygenase TauD, TfdA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 337.0
PYH1_k127_8288738_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
PYH1_k127_8288738_5 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 273.0
PYH1_k127_8288738_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000003215 181.0
PYH1_k127_8288738_7 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000000000006067 122.0
PYH1_k127_8288738_8 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000001487 124.0
PYH1_k127_8288738_9 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000008859 114.0
PYH1_k127_8312705_0 Periplasmic binding protein domain K01999 - - 2.967e-203 641.0
PYH1_k127_8312705_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 391.0
PYH1_k127_8312705_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 357.0
PYH1_k127_8312705_3 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 357.0
PYH1_k127_8312705_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
PYH1_k127_8357509_0 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 507.0
PYH1_k127_8357509_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 477.0
PYH1_k127_852564_0 benzoyl-CoA oxygenase - - - 9.056e-236 747.0
PYH1_k127_852564_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 1.124e-223 706.0
PYH1_k127_852564_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 343.0
PYH1_k127_852564_11 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000001053 235.0
PYH1_k127_852564_12 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000007552 126.0
PYH1_k127_852564_13 HD domain - - - 0.00000000000000000000000004311 126.0
PYH1_k127_852564_14 oxidation-reduction process - - - 0.000000000000000000000000233 117.0
PYH1_k127_852564_15 Anti-sigma-K factor rskA - - - 0.000000000004047 76.0
PYH1_k127_852564_16 thiamine diphosphate biosynthetic process K03154 - - 0.00000000003584 70.0
PYH1_k127_852564_18 Protein of unknown function (DUF1569) - - - 0.000002113 57.0
PYH1_k127_852564_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 423.0
PYH1_k127_852564_3 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 444.0
PYH1_k127_852564_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 411.0
PYH1_k127_852564_5 Belongs to the TtcA family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 349.0
PYH1_k127_852564_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 346.0
PYH1_k127_852564_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 361.0
PYH1_k127_852564_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 362.0
PYH1_k127_852564_9 Histidine kinase K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 351.0
PYH1_k127_855080_0 ABC-type Fe3 transport system permease component K02011 - - 5.903e-212 672.0
PYH1_k127_855080_1 mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 544.0
PYH1_k127_855080_10 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001861 286.0
PYH1_k127_855080_11 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002467 288.0
PYH1_k127_855080_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006005 273.0
PYH1_k127_855080_13 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003727 272.0
PYH1_k127_855080_14 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
PYH1_k127_855080_15 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002356 250.0
PYH1_k127_855080_16 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000002233 252.0
PYH1_k127_855080_17 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000007101 256.0
PYH1_k127_855080_18 C-C_Bond_Lyase of the TIM-Barrel fold K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000008628 224.0
PYH1_k127_855080_19 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
PYH1_k127_855080_2 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 441.0
PYH1_k127_855080_20 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000003759 213.0
PYH1_k127_855080_21 - - - - 0.000000000000000000000000000000000000000000000000000005347 204.0
PYH1_k127_855080_22 Cell wall formation K00075,K01921 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 0.000000000000000000000000000000000000000000000000000172 198.0
PYH1_k127_855080_23 PFAM Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000008329 185.0
PYH1_k127_855080_24 domain, Protein - - - 0.000000000000000000000000000000000000000378 156.0
PYH1_k127_855080_25 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000003205 153.0
PYH1_k127_855080_26 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000004819 138.0
PYH1_k127_855080_27 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000001488 139.0
PYH1_k127_855080_28 - - - - 0.0000000000000000000000000000001709 140.0
PYH1_k127_855080_29 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000126 128.0
PYH1_k127_855080_3 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 427.0
PYH1_k127_855080_30 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000002073 121.0
PYH1_k127_855080_31 Endoribonuclease L-PSP - - - 0.000000000000000000008639 101.0
PYH1_k127_855080_32 rRNA (guanine-N2-)-methyltransferase activity - - - 0.000000000000000003374 93.0
PYH1_k127_855080_33 Cytochrome c K00406,K08906 - - 0.00000000002011 75.0
PYH1_k127_855080_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 416.0
PYH1_k127_855080_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 391.0
PYH1_k127_855080_6 epimerase, PhzC PhzF homolog - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 377.0
PYH1_k127_855080_7 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 383.0
PYH1_k127_855080_8 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 323.0
PYH1_k127_855080_9 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 310.0
PYH1_k127_874487_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 411.0
PYH1_k127_874487_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001464 287.0
PYH1_k127_874487_2 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000137 274.0
PYH1_k127_874487_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000004408 230.0
PYH1_k127_874487_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000004265 193.0
PYH1_k127_874487_5 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000004059 137.0
PYH1_k127_88260_0 Periplasmic binding protein domain K01999 - - 4.495e-204 644.0
PYH1_k127_88260_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 467.0
PYH1_k127_88260_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 451.0
PYH1_k127_88260_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 419.0
PYH1_k127_88260_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 362.0
PYH1_k127_88260_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 359.0
PYH1_k127_88260_6 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 319.0
PYH1_k127_88260_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000007475 200.0
PYH1_k127_88260_8 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000007858 108.0
PYH1_k127_88260_9 Isochorismatase family - - - 0.000000000000000000000000839 112.0
PYH1_k127_883976_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 495.0
PYH1_k127_883976_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 441.0
PYH1_k127_883976_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 396.0
PYH1_k127_883976_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
PYH1_k127_883976_4 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 383.0
PYH1_k127_883976_5 - - - - 0.000000000000000000000000000000000000000000000000000000005 207.0
PYH1_k127_883976_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000215 209.0
PYH1_k127_907058_0 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 2.464e-204 645.0
PYH1_k127_907058_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 358.0
PYH1_k127_907058_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000001618 196.0
PYH1_k127_907058_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000001733 164.0
PYH1_k127_907058_12 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.0000000000000000000000727 103.0
PYH1_k127_907058_2 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 356.0
PYH1_k127_907058_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 353.0
PYH1_k127_907058_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 294.0
PYH1_k127_907058_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002495 274.0
PYH1_k127_907058_6 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000006896 249.0
PYH1_k127_907058_7 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000001757 230.0
PYH1_k127_907058_8 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
PYH1_k127_907058_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000002385 222.0
PYH1_k127_910562_0 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 379.0
PYH1_k127_910562_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
PYH1_k127_910562_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000005506 171.0
PYH1_k127_910562_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000005114 97.0
PYH1_k127_9623_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 3.955e-218 694.0
PYH1_k127_9623_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 576.0
PYH1_k127_9623_2 Transglycosylase K05365,K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 565.0
PYH1_k127_9623_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 451.0
PYH1_k127_9623_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 404.0
PYH1_k127_9623_5 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 362.0
PYH1_k127_9623_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 290.0
PYH1_k127_9623_7 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000001018 136.0
PYH1_k127_9623_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000001292 96.0