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Overview

ID MAG03127
Name PYH1_bin.14
Sample SMP0073
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order RBG-16-68-12
Family RBG-16-68-12
Genus EA-19
Species
Assembly information
Completeness (%) 73.76
Contamination (%) 1.71
GC content (%) 68.0
N50 (bp) 4,345
Genome size (bp) 1,539,767

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1429

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1005651_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 569.0
PYH1_k127_1005651_1 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000002307 143.0
PYH1_k127_1005651_2 Thiamine-binding protein - - - 0.000000000000000000000000001205 115.0
PYH1_k127_1005651_3 Peptidase family M54 K06974 - - 0.000000000000000000000005775 118.0
PYH1_k127_1005651_4 O-methyltransferase activity K03183,K15256 - 2.1.1.163,2.1.1.201 0.0000000000000001087 89.0
PYH1_k127_1023183_0 ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 442.0
PYH1_k127_1054420_0 Sodium hydrogen exchanger - - - 0.00000000000001927 77.0
PYH1_k127_1068843_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000001915 168.0
PYH1_k127_1068843_1 PFAM CBS domain containing protein - - - 0.0000000000000000001931 94.0
PYH1_k127_1068843_2 Serine threonine protein kinase - - - 0.000001442 59.0
PYH1_k127_1074693_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 465.0
PYH1_k127_1074693_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 362.0
PYH1_k127_1074693_2 LUD domain - - - 0.00000000000000000000000000000000001024 153.0
PYH1_k127_1074693_3 Translation initiation factor K03680 - - 0.0000000000000000000000000006711 124.0
PYH1_k127_1085864_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 286.0
PYH1_k127_1085864_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000009758 177.0
PYH1_k127_1085864_2 M42 glutamyl aminopeptidase - - - 0.00000000000000002308 87.0
PYH1_k127_1085864_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000003827 59.0
PYH1_k127_1133417_0 Acyl-CoA dehydrogenase, middle domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 409.0
PYH1_k127_1133417_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 293.0
PYH1_k127_1133417_2 Acetyltransferase (GNAT) domain - - - 0.00005792 53.0
PYH1_k127_1134804_0 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000005463 224.0
PYH1_k127_1155471_0 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.00000000000000000000000000000000000000000000000000000000000004194 217.0
PYH1_k127_1155471_1 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.00000000000000002177 85.0
PYH1_k127_1171834_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 415.0
PYH1_k127_1171834_1 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000007401 117.0
PYH1_k127_1171834_2 PFAM AIG2 family protein - - - 0.0000000003881 66.0
PYH1_k127_1190084_0 Toprim domain K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
PYH1_k127_1190084_1 metal ion binding - - - 0.00000000000000000002003 100.0
PYH1_k127_1190084_2 Belongs to the UPF0235 family K09131 - - 0.00000000003316 67.0
PYH1_k127_1190280_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 619.0
PYH1_k127_1190280_1 ABC-2 family transporter protein K01992 - - 0.00002064 51.0
PYH1_k127_1214509_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 309.0
PYH1_k127_1214509_1 Right handed beta helix region - - - 0.00001512 55.0
PYH1_k127_1225987_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 474.0
PYH1_k127_1225987_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 459.0
PYH1_k127_1225987_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000002602 100.0
PYH1_k127_1225987_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000144 87.0
PYH1_k127_1324847_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000004697 211.0
PYH1_k127_1324847_1 - - - - 0.00005823 51.0
PYH1_k127_1329118_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1045.0
PYH1_k127_1329118_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000007424 227.0
PYH1_k127_1329118_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000001328 65.0
PYH1_k127_1362184_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 543.0
PYH1_k127_1362184_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 516.0
PYH1_k127_1362184_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 489.0
PYH1_k127_1362184_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 314.0
PYH1_k127_1362184_4 - - - - 0.00000006086 62.0
PYH1_k127_1362184_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00002869 54.0
PYH1_k127_1371938_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K22441 - 2.3.1.57 0.0003317 53.0
PYH1_k127_1375926_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000004344 209.0
PYH1_k127_1375926_1 homolog of PrgY (pheromone shutdown protein) - - - 0.0000000000000000000000000002978 125.0
PYH1_k127_1406394_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.814e-195 632.0
PYH1_k127_1406394_1 Transcriptional regulator, MarR family - - - 0.00000001012 66.0
PYH1_k127_1442950_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 341.0
PYH1_k127_1442950_1 PFAM PKD domain containing protein - - - 0.0000000001036 73.0
PYH1_k127_1449090_0 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000007577 179.0
PYH1_k127_1449090_1 CYTH domain - - - 0.000000000000000000001623 102.0
PYH1_k127_1449090_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000003491 100.0
PYH1_k127_1449090_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000001134 69.0
PYH1_k127_1449090_4 acetyltransferase - - - 0.00000161 56.0
PYH1_k127_145385_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 356.0
PYH1_k127_145385_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 325.0
PYH1_k127_145385_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001306 283.0
PYH1_k127_1477355_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 437.0
PYH1_k127_1477355_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000003074 157.0
PYH1_k127_1509150_0 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000002762 133.0
PYH1_k127_1509150_1 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000002603 118.0
PYH1_k127_1509150_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000001198 109.0
PYH1_k127_1509150_3 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000001263 108.0
PYH1_k127_1578779_0 - - - - 0.00000000000000001852 89.0
PYH1_k127_1578779_1 Esterase PHB depolymerase - - - 0.000000000000876 81.0
PYH1_k127_1613561_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004556 263.0
PYH1_k127_1613561_1 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007698 255.0
PYH1_k127_1613561_2 - - - - 0.0000000479 60.0
PYH1_k127_1613561_3 - - - - 0.0007542 50.0
PYH1_k127_1657217_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 321.0
PYH1_k127_1657217_1 PFAM S-layer - - - 0.000000000000000000000000000000000000000000000000000001254 203.0
PYH1_k127_1657217_2 Regulatory protein Crp K07730 - - 0.00000000000000000000000000000339 130.0
PYH1_k127_1657217_3 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000002031 84.0
PYH1_k127_1657217_4 Domain of unknown function (DUF4430) - - - 0.0000005211 57.0
PYH1_k127_1671484_0 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000007001 250.0
PYH1_k127_1671484_1 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000001839 228.0
PYH1_k127_1671484_2 archaeal coiled-coil protein - - - 0.00000000000000000000000001362 123.0
PYH1_k127_1672189_0 KH, type 1, domain K07041 - - 2.278e-264 828.0
PYH1_k127_1672189_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 3.7e-225 709.0
PYH1_k127_1672189_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000004694 241.0
PYH1_k127_1672189_3 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000000000000006642 93.0
PYH1_k127_1672189_4 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000002622 86.0
PYH1_k127_1672189_5 Acetyltransferase (GNAT) domain - - - 0.0004568 49.0
PYH1_k127_1740720_0 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 405.0
PYH1_k127_1740720_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000009816 179.0
PYH1_k127_1747797_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000003785 200.0
PYH1_k127_1747797_1 - - - - 0.00000000000000000000000000000000000000000000000001161 187.0
PYH1_k127_1791689_0 - - - - 0.000000000000000001465 89.0
PYH1_k127_1791689_1 - - - - 0.0000000000000006154 87.0
PYH1_k127_1791689_2 - - - - 0.00000000000004628 79.0
PYH1_k127_1809857_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 492.0
PYH1_k127_1809857_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 374.0
PYH1_k127_1809857_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 308.0
PYH1_k127_1809857_3 membrane - - - 0.00000000003807 70.0
PYH1_k127_1809857_4 peptidase M36 K01417 - - 0.000008629 56.0
PYH1_k127_1891409_0 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000004692 157.0
PYH1_k127_1891409_1 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters K02008 - - 0.000000000002015 77.0
PYH1_k127_1891409_2 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.0004005 46.0
PYH1_k127_1896025_0 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 307.0
PYH1_k127_1896025_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 272.0
PYH1_k127_1896025_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004276 265.0
PYH1_k127_1896025_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000004455 116.0
PYH1_k127_1896025_4 - - - - 0.00000000000000003173 86.0
PYH1_k127_1949905_0 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 459.0
PYH1_k127_1949905_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000005372 189.0
PYH1_k127_1949905_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000005681 95.0
PYH1_k127_19537_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 584.0
PYH1_k127_19537_1 Protein conserved in bacteria K07192 - - 0.00000000000000000000000000000000000000000004105 173.0
PYH1_k127_19537_2 PRC-barrel domain - - - 0.00000000000000000000000003399 110.0
PYH1_k127_1972463_0 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
PYH1_k127_1972463_1 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000002757 202.0
PYH1_k127_1992611_0 Aldo/keto reductase family K00002 - 1.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 367.0
PYH1_k127_1992611_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 305.0
PYH1_k127_1992611_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 291.0
PYH1_k127_1992611_3 biosynthesis protein QueC K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000001921 187.0
PYH1_k127_1992611_4 Ferric reductase NAD binding domain - - - 0.00000000000000000000000000000000000000000001019 171.0
PYH1_k127_1992611_5 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000000000002375 100.0
PYH1_k127_1992611_6 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000002569 85.0
PYH1_k127_1992611_7 Cupin domain - - - 0.0000000006385 63.0
PYH1_k127_2029863_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 434.0
PYH1_k127_2029863_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 344.0
PYH1_k127_2029863_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000001656 132.0
PYH1_k127_2036675_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000002 113.0
PYH1_k127_2040813_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000004941 179.0
PYH1_k127_2040813_1 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000001342 89.0
PYH1_k127_2040813_2 TIGRFAM Outer membrane protein K13735,K20276 - - 0.000000001857 72.0
PYH1_k127_2041635_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 393.0
PYH1_k127_2041635_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 316.0
PYH1_k127_2041635_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
PYH1_k127_2041635_3 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000002233 237.0
PYH1_k127_2041635_4 - - - - 0.0000000000000000000000009309 108.0
PYH1_k127_2041635_5 KaiC - - - 0.0000000000000001243 89.0
PYH1_k127_2041635_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0001548 46.0
PYH1_k127_2066539_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000009964 261.0
PYH1_k127_2066539_1 anaphase-promoting complex binding - - - 0.00000000000000000000403 109.0
PYH1_k127_2066539_2 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000000001818 78.0
PYH1_k127_2110937_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.913e-225 718.0
PYH1_k127_2110937_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 367.0
PYH1_k127_2110937_2 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000005469 162.0
PYH1_k127_2110937_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000001343 110.0
PYH1_k127_2110937_4 - - - - 0.000000000000000001032 91.0
PYH1_k127_2110937_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000002815 78.0
PYH1_k127_2110937_6 Predicted membrane protein (DUF2085) - - - 0.0000000000002387 79.0
PYH1_k127_2110937_7 helix_turn_helix ASNC type K03719 - - 0.000000000003621 71.0
PYH1_k127_2110937_8 ribosomal small subunit binding - - - 0.000008902 55.0
PYH1_k127_2111207_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 1.358e-200 636.0
PYH1_k127_2119575_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000009171 229.0
PYH1_k127_2119575_1 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000002287 196.0
PYH1_k127_2119575_2 PAC2 family K06869 - - 0.00000000000000000000000000000000000000002216 162.0
PYH1_k127_2119575_3 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000003067 83.0
PYH1_k127_2119575_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00007901 46.0
PYH1_k127_2121764_0 Required for chromosome condensation and partitioning K03529 - - 1.509e-224 736.0
PYH1_k127_2121764_1 - - - - 0.00000000000000000000000000000001524 132.0
PYH1_k127_2121764_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000007546 123.0
PYH1_k127_2124639_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000003875 273.0
PYH1_k127_2124639_1 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000002278 92.0
PYH1_k127_2124639_2 aminopeptidase activity - - - 0.0000000000003674 77.0
PYH1_k127_2132950_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 538.0
PYH1_k127_2132950_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000296 248.0
PYH1_k127_2132950_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.0000000000000000000000000000000083 136.0
PYH1_k127_2132950_3 Acetyltransferase (GNAT) domain - - - 0.00000000002534 76.0
PYH1_k127_2132950_4 cell adhesion involved in biofilm formation K02014,K16087,K20276 - - 0.00000000206 66.0
PYH1_k127_2137980_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000006423 74.0
PYH1_k127_2137980_1 methylenetetrahydrofolate reductase (NAD(P)H) activity - - - 0.000000002982 68.0
PYH1_k127_2144683_0 Tetratricopeptide repeat - - - 0.00000000000000000000000003021 125.0
PYH1_k127_2144683_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000005274 114.0
PYH1_k127_2168861_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K00342,K05568 - 1.6.5.3 0.0 1125.0
PYH1_k127_2168861_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 574.0
PYH1_k127_2168861_10 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K00338 - 1.6.5.3 0.00000000000000000000000003166 117.0
PYH1_k127_2168861_12 - - - - 0.0000000000001534 83.0
PYH1_k127_2168861_13 Multisubunit Na H antiporter MnhC subunit K00340,K05567,K14114 - 1.6.5.3 0.0000001736 60.0
PYH1_k127_2168861_14 SPFH domain-Band 7 family - - - 0.0003189 45.0
PYH1_k127_2168861_2 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 479.0
PYH1_k127_2168861_3 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 349.0
PYH1_k127_2168861_4 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 310.0
PYH1_k127_2168861_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.0000000000000000000000000000000000000000000000000000000000000002059 224.0
PYH1_k127_2168861_6 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000007212 147.0
PYH1_k127_2168861_7 Hydrogenase maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000000000000000000001874 136.0
PYH1_k127_2168861_8 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.000000000000000000000000003567 123.0
PYH1_k127_2168861_9 EamA-like transporter family - - - 0.000000000000000000000000009975 121.0
PYH1_k127_2173325_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.66e-230 732.0
PYH1_k127_2173325_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000189 218.0
PYH1_k127_2173325_2 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000009891 209.0
PYH1_k127_2173325_3 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000002796 217.0
PYH1_k127_2173325_4 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000008668 155.0
PYH1_k127_2173325_5 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000000002981 157.0
PYH1_k127_2173325_6 Major facilitator superfamily - - - 0.000000000000000000000000000002405 136.0
PYH1_k127_2173325_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000004718 81.0
PYH1_k127_2173325_8 DNA polymerase beta domain protein region - - - 0.000003728 54.0
PYH1_k127_2191871_0 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001671 268.0
PYH1_k127_2191871_1 Belongs to the peptidase S8 family - - - 0.00000000000000000008082 107.0
PYH1_k127_2191871_2 Winged helix-turn-helix DNA-binding - - - 0.0000000118 62.0
PYH1_k127_2191871_4 Protein of unknown function (DUF504) K09715 - - 0.0002238 52.0
PYH1_k127_2191871_5 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.0006037 54.0
PYH1_k127_2217599_0 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 473.0
PYH1_k127_2217599_1 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 357.0
PYH1_k127_2289603_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.047e-260 819.0
PYH1_k127_2289603_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 405.0
PYH1_k127_2289603_2 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000000000000000000000000000000000000000000101 200.0
PYH1_k127_2289603_3 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000001826 140.0
PYH1_k127_2289603_4 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000005799 131.0
PYH1_k127_2289603_5 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000006676 132.0
PYH1_k127_2289603_6 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000001002 125.0
PYH1_k127_2290161_0 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000001121 212.0
PYH1_k127_2290161_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000004924 204.0
PYH1_k127_2290161_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000002744 103.0
PYH1_k127_2290161_3 Circadian clock protein KaiC K06945 - - 0.0002778 52.0
PYH1_k127_2304359_0 amino acid - - - 0.000000000000000000000000000000000000000008411 166.0
PYH1_k127_2304359_1 Ras of Complex, Roc, domain of DAPkinase - - - 0.000000000000000000001669 100.0
PYH1_k127_2326792_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1075.0
PYH1_k127_2326792_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000135 220.0
PYH1_k127_2326792_2 Membrane - - - 0.00000000000000000000000000000002694 136.0
PYH1_k127_2326792_3 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000000004493 104.0
PYH1_k127_234644_0 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000003945 255.0
PYH1_k127_234644_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 - - 0.000000000000000000000000000000000000000000003354 174.0
PYH1_k127_234644_2 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.000000000000000000001062 104.0
PYH1_k127_2362680_0 Helix-hairpin-helix motif K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004029 247.0
PYH1_k127_2362680_1 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000004606 156.0
PYH1_k127_2362680_2 RNA polymerase K03051 - 2.7.7.6 0.000000000000000000006385 96.0
PYH1_k127_2362680_3 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000005169 70.0
PYH1_k127_2363158_0 Uncharacterized protein family (UPF0051) K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 540.0
PYH1_k127_2363158_1 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 345.0
PYH1_k127_2371402_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 361.0
PYH1_k127_2371402_1 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000001132 137.0
PYH1_k127_2371402_2 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000001232 113.0
PYH1_k127_2371402_3 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000008777 106.0
PYH1_k127_2371402_4 - - - - 0.00000000000003939 78.0
PYH1_k127_2371402_5 zinc-ribbon domain - - - 0.00000000008981 63.0
PYH1_k127_2371402_6 Lrp/AsnC ligand binding domain - - - 0.000026 53.0
PYH1_k127_2383891_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000171 254.0
PYH1_k127_2383891_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000465 228.0
PYH1_k127_2388639_0 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000245 184.0
PYH1_k127_2388639_1 ParB-like nuclease domain - - - 0.00000000000000000000816 97.0
PYH1_k127_2388639_2 PRC-barrel domain - - - 0.00000000000000002249 88.0
PYH1_k127_2388639_3 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000005733 59.0
PYH1_k127_2397367_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.00000000001058 77.0
PYH1_k127_2397367_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000001879 64.0
PYH1_k127_2400261_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 296.0
PYH1_k127_2400261_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001126 255.0
PYH1_k127_2400261_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000001461 220.0
PYH1_k127_2400261_3 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000002219 217.0
PYH1_k127_2400261_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000018 143.0
PYH1_k127_2400261_5 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000001821 138.0
PYH1_k127_2400261_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000000001409 98.0
PYH1_k127_2400261_7 Pfam:Arch_ATPase - - - 0.0000009785 59.0
PYH1_k127_2400261_8 Parallel beta-helix repeats - - - 0.00003146 57.0
PYH1_k127_2428453_0 Bacterial transcriptional activator domain - - - 0.0000000000000007527 90.0
PYH1_k127_2428701_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.237e-247 790.0
PYH1_k127_2428701_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000009881 169.0
PYH1_k127_2431274_0 COG1520 FOG WD40-like repeat - - - 0.0000000000000000005468 95.0
PYH1_k127_2431274_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000001456 95.0
PYH1_k127_2496327_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
PYH1_k127_2496327_1 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000682 87.0
PYH1_k127_2496327_2 pfam nmd3 K07562 - - 0.00000000000000004677 87.0
PYH1_k127_2498713_0 PFAM helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 483.0
PYH1_k127_2498713_1 - - - - 0.000000001984 70.0
PYH1_k127_2511007_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 600.0
PYH1_k127_2511007_1 - - - - 0.00000000000000000000008092 101.0
PYH1_k127_2511007_2 - - - - 0.0000000001178 68.0
PYH1_k127_2511007_3 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.0000000006005 64.0
PYH1_k127_2534194_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000003254 83.0
PYH1_k127_254211_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 395.0
PYH1_k127_254211_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 387.0
PYH1_k127_2556551_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 5.776e-200 632.0
PYH1_k127_2556551_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000002484 191.0
PYH1_k127_2556551_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000006486 91.0
PYH1_k127_2560624_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 461.0
PYH1_k127_2560624_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 431.0
PYH1_k127_2560624_2 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 405.0
PYH1_k127_2560624_3 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000002375 197.0
PYH1_k127_2560624_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000001069 180.0
PYH1_k127_2560624_5 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.0000000000000000000000000000000000000005306 160.0
PYH1_k127_2560624_6 - - - - 0.00000000000000000001406 93.0
PYH1_k127_2562215_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 331.0
PYH1_k127_2562215_1 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000009211 203.0
PYH1_k127_256406_0 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002447 261.0
PYH1_k127_256406_1 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002021 214.0
PYH1_k127_256406_2 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000003961 176.0
PYH1_k127_256406_3 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001481 111.0
PYH1_k127_256406_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000001618 90.0
PYH1_k127_2564703_0 FeS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 303.0
PYH1_k127_2564703_1 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000002006 137.0
PYH1_k127_2564703_2 Carbon-nitrogen hydrolase - - - 0.00007059 52.0
PYH1_k127_2596149_0 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000006254 173.0
PYH1_k127_2596149_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000006659 130.0
PYH1_k127_2596149_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000005028 105.0
PYH1_k127_2608922_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 405.0
PYH1_k127_2608922_1 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006875 284.0
PYH1_k127_2608922_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000005797 226.0
PYH1_k127_2608922_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000007279 160.0
PYH1_k127_2608922_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000329 112.0
PYH1_k127_2608922_5 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000004903 87.0
PYH1_k127_2609737_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 2.363e-195 632.0
PYH1_k127_2609737_1 LemA family K03744 - - 0.00000000000000000000000000000000000623 144.0
PYH1_k127_2609737_2 TPM domain K06872 - - 0.000000000000000000000000000002293 128.0
PYH1_k127_2609737_3 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000004097 76.0
PYH1_k127_2625530_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 445.0
PYH1_k127_2625530_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
PYH1_k127_2625530_2 Protein of unknown function (DUF1349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000414 282.0
PYH1_k127_2625530_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000005005 244.0
PYH1_k127_2625530_4 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000002261 148.0
PYH1_k127_2625530_5 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000001852 134.0
PYH1_k127_2625530_6 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000004172 88.0
PYH1_k127_2625530_7 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000278 81.0
PYH1_k127_2625530_8 protein conserved in archaea - - - 0.00000000001103 79.0
PYH1_k127_2649927_0 Right handed beta helix region - - - 0.000001922 61.0
PYH1_k127_2678666_0 - - - - 0.000000000000000000000000000000000000000000000000008141 187.0
PYH1_k127_2678666_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050662,GO:0051287,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.23 0.000000000004156 70.0
PYH1_k127_2679073_0 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 329.0
PYH1_k127_2699120_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009957 284.0
PYH1_k127_2699120_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000006883 88.0
PYH1_k127_2699120_2 ABC-2 type transporter K01992 - - 0.000000000003814 77.0
PYH1_k127_2699120_3 RNA ligase activity K14415,K18148 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0030312,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.000000004856 58.0
PYH1_k127_2708486_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 2.031e-224 721.0
PYH1_k127_2708486_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 539.0
PYH1_k127_2708486_2 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 431.0
PYH1_k127_2708486_3 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 367.0
PYH1_k127_2708486_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 325.0
PYH1_k127_2708486_5 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 310.0
PYH1_k127_2708486_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K18358,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.1.58,1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000004211 196.0
PYH1_k127_2708486_7 VanZ like family - - - 0.00000000006939 69.0
PYH1_k127_2708486_8 VKc - - - 0.000000007817 60.0
PYH1_k127_2719415_0 - - - - 0.000607 47.0
PYH1_k127_2744777_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000004727 59.0
PYH1_k127_2796963_0 Metallo-beta-lactamase superfamily K12574 - - 0.000000000000000000000000000000000000000000001035 179.0
PYH1_k127_2796963_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000002749 127.0
PYH1_k127_2801463_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 317.0
PYH1_k127_2801463_1 COG0531 Amino acid transporters - - - 0.00000000000000000000000000005388 131.0
PYH1_k127_2801463_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000006993 118.0
PYH1_k127_2801463_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000005518 103.0
PYH1_k127_2801463_4 Mechanosensitive ion channel - - - 0.000000000000000000002103 108.0
PYH1_k127_2801463_5 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000006292 80.0
PYH1_k127_2801463_6 Domain of unknown function (DUF1610) K07580 - - 0.0000000000003683 70.0
PYH1_k127_2830219_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001955 250.0
PYH1_k127_2830219_1 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000002374 61.0
PYH1_k127_2847885_0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000001235 220.0
PYH1_k127_2847885_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000684 83.0
PYH1_k127_2899082_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000164 118.0
PYH1_k127_2899542_0 Glycerol-3-phosphate dehydrogenase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 344.0
PYH1_k127_2899542_1 PFAM Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000003405 229.0
PYH1_k127_2899542_2 FAD linked K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000001446 181.0
PYH1_k127_2899542_3 Protein of unknown function (DUF981) K08980 - - 0.0000000000000000000000000000007137 128.0
PYH1_k127_2928754_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009334 259.0
PYH1_k127_2928754_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.0000000000000000000000000000000000000001245 170.0
PYH1_k127_2928754_2 PFAM B3 4 domain - - - 0.000000000000000000000000000000000006937 140.0
PYH1_k127_2970527_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.368e-227 724.0
PYH1_k127_2970527_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 561.0
PYH1_k127_2970527_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 430.0
PYH1_k127_2970527_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000001149 175.0
PYH1_k127_2973106_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 365.0
PYH1_k127_2973106_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000003861 51.0
PYH1_k127_2982375_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 315.0
PYH1_k127_2982375_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000003833 228.0
PYH1_k127_2982375_2 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000003296 133.0
PYH1_k127_2982375_3 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000001146 127.0
PYH1_k127_2982375_4 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000192 82.0
PYH1_k127_2984334_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 612.0
PYH1_k127_2984334_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 329.0
PYH1_k127_2984334_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0000000000000000000000000000000000000000000000002134 182.0
PYH1_k127_2984334_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000002182 105.0
PYH1_k127_2984334_4 but it may be involved in stabilization of the trimeric complex - - - 0.00004969 53.0
PYH1_k127_2990844_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 2.094e-225 717.0
PYH1_k127_2990844_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 304.0
PYH1_k127_2990844_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.000000000000000000000000000000000000000000000000000003464 195.0
PYH1_k127_2990844_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000214 162.0
PYH1_k127_2990844_4 - - - - 0.000000000000000000000000001391 120.0
PYH1_k127_2990844_5 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000001913 94.0
PYH1_k127_2990844_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000001214 92.0
PYH1_k127_2990844_7 KaiC K08482 - - 0.00000000002303 74.0
PYH1_k127_302655_0 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 466.0
PYH1_k127_302655_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 386.0
PYH1_k127_302655_2 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 340.0
PYH1_k127_302655_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000002299 142.0
PYH1_k127_302655_4 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000007313 112.0
PYH1_k127_3041912_0 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000002853 219.0
PYH1_k127_3041912_1 Fungalysin metallopeptidase (M36) - - - 0.00000006624 66.0
PYH1_k127_3077133_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000008289 181.0
PYH1_k127_3077133_1 Glycosyltransferase like family 2 - - - 0.00000004778 64.0
PYH1_k127_3086212_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 1.903e-268 834.0
PYH1_k127_3086212_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 339.0
PYH1_k127_3110585_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
PYH1_k127_3110585_1 - - - - 0.00000000000000000000000000000000000000000000005656 175.0
PYH1_k127_3110585_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000343 53.0
PYH1_k127_311869_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 419.0
PYH1_k127_311869_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
PYH1_k127_311869_10 acid acetyltransferase K06718 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.178 0.0000004235 60.0
PYH1_k127_311869_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000001464 51.0
PYH1_k127_311869_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 312.0
PYH1_k127_311869_3 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000008957 209.0
PYH1_k127_311869_4 COGs COG4328 conserved - - - 0.000000000000000000000000000000000000000000000000000501 196.0
PYH1_k127_311869_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000001749 176.0
PYH1_k127_311869_6 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000002823 114.0
PYH1_k127_311869_7 - - - - 0.000000000003997 70.0
PYH1_k127_311869_8 Possibly the antitoxin component of a - - - 0.000000004153 61.0
PYH1_k127_311869_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000004894 65.0
PYH1_k127_3120509_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.264e-196 628.0
PYH1_k127_3120509_1 EamA-like transporter family - - - 0.000000000426 71.0
PYH1_k127_3160731_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000008785 228.0
PYH1_k127_3160731_1 - - - - 0.0000000000000000000000000000000002505 141.0
PYH1_k127_3160731_2 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000001684 142.0
PYH1_k127_3160731_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000007214 83.0
PYH1_k127_317028_0 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 352.0
PYH1_k127_317028_1 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000008462 168.0
PYH1_k127_3181587_0 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.0004406 55.0
PYH1_k127_3229590_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 391.0
PYH1_k127_3229590_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 370.0
PYH1_k127_3229590_2 FAD binding domain K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004563 286.0
PYH1_k127_3229590_3 ferredoxin-like protein K03855 - - 0.0000000000000000000000004275 108.0
PYH1_k127_3230389_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 4.362e-230 786.0
PYH1_k127_3230389_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 454.0
PYH1_k127_3230389_10 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000214 104.0
PYH1_k127_3230389_11 Belongs to the UPF0434 family - - - 0.00000000000000005855 86.0
PYH1_k127_3230389_12 - - - - 0.0000000008683 69.0
PYH1_k127_3230389_2 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 368.0
PYH1_k127_3230389_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 352.0
PYH1_k127_3230389_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 308.0
PYH1_k127_3230389_6 RNA-binding protein of the translin family K07477 - - 0.000000000000000000000000000000000000000000000000004744 188.0
PYH1_k127_3230389_7 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000003737 155.0
PYH1_k127_3230389_9 Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000004592 169.0
PYH1_k127_3288937_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 597.0
PYH1_k127_3288937_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001582 261.0
PYH1_k127_3290416_0 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.000000000000000000000000000000000000000000000000000000007434 207.0
PYH1_k127_3290416_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000004403 176.0
PYH1_k127_3290416_2 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000449 123.0
PYH1_k127_3290416_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000001824 58.0
PYH1_k127_3302456_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 319.0
PYH1_k127_3302456_1 ATP synthase subunit C K02124 - - 0.0000008214 53.0
PYH1_k127_3302456_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000001012 54.0
PYH1_k127_3338917_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 3.776e-200 642.0
PYH1_k127_3338917_1 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 321.0
PYH1_k127_3338917_2 Protein disulfide isomerase family A, member 5 K01829,K09583 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0006457,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010033,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0023052,GO:0030968,GO:0031974,GO:0031984,GO:0033554,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036498,GO:0042175,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0098827,GO:0140096 5.3.4.1 0.00000001864 63.0
PYH1_k127_3342251_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 319.0
PYH1_k127_3342251_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000001625 159.0
PYH1_k127_3342251_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000002367 147.0
PYH1_k127_3342251_3 Winged helix DNA-binding domain - - - 0.0000000000000000001055 92.0
PYH1_k127_3342251_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000002048 57.0
PYH1_k127_3424249_0 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003103 261.0
PYH1_k127_3424249_1 PFAM peptidase M50 - - - 0.00000000000000000000000000000000009945 144.0
PYH1_k127_3424249_2 ATP-dependent helicase activity K10844 - 3.6.4.12 0.00000000000001106 87.0
PYH1_k127_3428291_0 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000000001228 119.0
PYH1_k127_3428291_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000001279 86.0
PYH1_k127_3476700_0 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.000000000000000000000000000000000000000000000001005 187.0
PYH1_k127_3476700_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000007062 124.0
PYH1_k127_3480342_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009371 280.0
PYH1_k127_3480342_1 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.00005332 54.0
PYH1_k127_3508716_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000175 210.0
PYH1_k127_3508716_1 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000001542 177.0
PYH1_k127_3508716_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000008811 162.0
PYH1_k127_3508716_3 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.00000000000000000000000000000000002883 136.0
PYH1_k127_3508716_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000146 113.0
PYH1_k127_3508716_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000716 96.0
PYH1_k127_3508716_6 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000003749 98.0
PYH1_k127_351866_0 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 362.0
PYH1_k127_351866_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000003408 152.0
PYH1_k127_351866_2 - - - - 0.0000000000000000000000267 111.0
PYH1_k127_3526384_0 Hep Hag repeat protein K19233,K21449 - - 0.000000002888 70.0
PYH1_k127_3526384_1 Periplasmic or secreted lipoprotein - - - 0.0000002416 64.0
PYH1_k127_3526384_2 Membrane - - - 0.000002815 59.0
PYH1_k127_3575614_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 590.0
PYH1_k127_3575614_1 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000001498 229.0
PYH1_k127_3575614_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000003485 200.0
PYH1_k127_3578567_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 456.0
PYH1_k127_3578567_1 ABC transporter, ATP-binding protein K02028,K17076 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 311.0
PYH1_k127_3578567_2 amino acid ABC transporter K02029 - - 0.00000000000000000000000000000002403 137.0
PYH1_k127_3578567_3 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000000000000000001207 123.0
PYH1_k127_3578567_4 ABC transporter K02029 - - 0.0000000000000000000000005791 117.0
PYH1_k127_3578567_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000002013 83.0
PYH1_k127_3578567_6 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.0000000000003174 72.0
PYH1_k127_3578567_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00009202 45.0
PYH1_k127_3589099_0 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000000000000000001142 207.0
PYH1_k127_3589099_1 Double zinc ribbon - - - 0.0000000004229 69.0
PYH1_k127_3622092_0 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000003798 153.0
PYH1_k127_3622092_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000001856 112.0
PYH1_k127_3622092_2 Pkd domain containing protein - - - 0.0000000665 62.0
PYH1_k127_3642588_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 499.0
PYH1_k127_3642588_1 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 382.0
PYH1_k127_3642588_2 electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
PYH1_k127_3642588_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.0000000000000000000000000000000000000000004363 181.0
PYH1_k127_3642624_0 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000001531 107.0
PYH1_k127_3642624_1 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000005229 92.0
PYH1_k127_3642624_2 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000002164 92.0
PYH1_k127_3642624_3 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000007075 81.0
PYH1_k127_3642624_4 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000001357 68.0
PYH1_k127_3642624_5 ABC-type multidrug transport system ATPase component K01990 - - 0.0000001054 55.0
PYH1_k127_3642624_6 - K20478 - - 0.0005135 53.0
PYH1_k127_3652583_0 Protein of unknown function (DUF835) - - - 0.0001428 52.0
PYH1_k127_3652583_1 Protein of unknown function (DUF835) - - - 0.000619 50.0
PYH1_k127_3667586_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1341.0
PYH1_k127_3667586_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 484.0
PYH1_k127_3697946_0 DEAD/H associated K03724 - - 0.0 1452.0
PYH1_k127_3697946_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 317.0
PYH1_k127_3697946_2 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 317.0
PYH1_k127_3697946_3 Protein of unknown function (DUF1349) - - - 0.0000000000000000000000000000000000000000000000000000000006592 231.0
PYH1_k127_3697946_4 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000002161 78.0
PYH1_k127_369914_0 von Willebrand factor, type A - - - 0.0000000000000000007683 101.0
PYH1_k127_369914_1 Protein of unknown function (DUF1349) - - - 0.0000001813 64.0
PYH1_k127_3705626_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 430.0
PYH1_k127_3705626_1 Citrate transporter - - - 0.000000000000000000000000000000000005769 146.0
PYH1_k127_3705626_2 PFAM PKD domain containing protein - - - 0.00000000000000000004975 107.0
PYH1_k127_3717351_0 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000000000000005218 237.0
PYH1_k127_3723075_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 334.0
PYH1_k127_3723075_1 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000001813 237.0
PYH1_k127_3723075_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003806 134.0
PYH1_k127_3723075_3 COG0457 FOG TPR repeat - - - 0.00007615 55.0
PYH1_k127_3724523_0 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
PYH1_k127_3724523_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000137 137.0
PYH1_k127_3724523_2 Peptidase inhibitor I9 - - - 0.00003431 55.0
PYH1_k127_3747797_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000006086 132.0
PYH1_k127_3797451_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 461.0
PYH1_k127_3797451_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 334.0
PYH1_k127_3797451_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000001734 97.0
PYH1_k127_3797451_3 - - - - 0.000000008624 66.0
PYH1_k127_3797508_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 387.0
PYH1_k127_3797508_1 1,7-bisphosphate phosphatase - - - 0.000000000000000000000000000000000000009864 157.0
PYH1_k127_3798527_0 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 484.0
PYH1_k127_3798527_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 451.0
PYH1_k127_3798527_2 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000002052 241.0
PYH1_k127_3798527_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000007944 60.0
PYH1_k127_3798527_4 COG2002 Regulators of stationary sporulation gene expression - - - 0.000007611 51.0
PYH1_k127_3828753_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007341 266.0
PYH1_k127_3828753_1 Protein of unknown function (DUF3494) - - - 0.000001818 59.0
PYH1_k127_3850738_0 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000252 289.0
PYH1_k127_3854708_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 435.0
PYH1_k127_3854708_1 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000001709 125.0
PYH1_k127_3896355_0 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 317.0
PYH1_k127_3896355_1 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000002901 113.0
PYH1_k127_3897223_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0001 54.0
PYH1_k127_3910659_0 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000000008974 134.0
PYH1_k127_3910659_1 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000001269 127.0
PYH1_k127_3940882_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
PYH1_k127_3940882_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000001134 139.0
PYH1_k127_3940882_2 Conserved repeat domain - - - 0.0000000000000000000000004477 118.0
PYH1_k127_3941256_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 419.0
PYH1_k127_398308_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 350.0
PYH1_k127_398308_1 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 323.0
PYH1_k127_3994916_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000000000000008725 112.0
PYH1_k127_3994916_1 PFAM Protein kinase domain - - - 0.0000001865 59.0
PYH1_k127_3995679_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 324.0
PYH1_k127_3995679_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000003301 190.0
PYH1_k127_407210_0 - - - - 0.0000000000000000000000006616 122.0
PYH1_k127_407210_1 nitrile biosynthetic process K20285 - - 0.0002255 55.0
PYH1_k127_4098114_0 - - - - 0.0000000000000000000000000001504 133.0
PYH1_k127_4098114_1 PFAM Glycosyl transferase, group 1 K14335 - - 0.0000002048 57.0
PYH1_k127_4119049_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 393.0
PYH1_k127_4119049_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
PYH1_k127_4119049_2 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000000000000004762 216.0
PYH1_k127_4119049_3 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000006067 99.0
PYH1_k127_4120197_1 Transglutaminase-like superfamily - - - 0.0000000000005454 82.0
PYH1_k127_4128623_0 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 276.0
PYH1_k127_4128623_1 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000008121 235.0
PYH1_k127_4163560_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000001797 67.0
PYH1_k127_4163560_2 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000461 63.0
PYH1_k127_4163560_3 - - - - 0.00000004449 59.0
PYH1_k127_4163560_4 - - - - 0.00000006275 57.0
PYH1_k127_4163560_5 HupF/HypC family K04653 - - 0.0000003559 58.0
PYH1_k127_4163560_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0005152 51.0
PYH1_k127_4166208_0 Beta-propeller repeat - - - 0.0000005483 56.0
PYH1_k127_4166933_0 GYD domain - - - 0.0000000000000000000007841 101.0
PYH1_k127_4201944_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 357.0
PYH1_k127_4201944_1 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 367.0
PYH1_k127_4201944_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 333.0
PYH1_k127_4201944_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 319.0
PYH1_k127_4201944_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002924 280.0
PYH1_k127_4201944_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000002309 241.0
PYH1_k127_4201944_6 DUF72 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000003296 222.0
PYH1_k127_4201944_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K18816 - 2.3.1.82 0.00000000783 64.0
PYH1_k127_4213991_0 protein conserved in archaea - - - 0.00000000001316 72.0
PYH1_k127_4227181_0 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 367.0
PYH1_k127_4227181_1 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 377.0
PYH1_k127_4227181_2 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 310.0
PYH1_k127_4227181_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001835 266.0
PYH1_k127_4227181_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000121 236.0
PYH1_k127_4227181_5 COG0500 SAM-dependent methyltransferases K03183 - 2.1.1.163,2.1.1.201 0.00000000000001085 81.0
PYH1_k127_4227181_6 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000001659 77.0
PYH1_k127_4227181_7 poly-hydroxybutyrate biosynthetic process - - - 0.0000008463 58.0
PYH1_k127_4227181_8 nucleic acid-binding protein K07065 - - 0.0001089 49.0
PYH1_k127_4249055_0 domain protein K20276 - - 0.000000000000001594 91.0
PYH1_k127_4254779_0 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000002486 98.0
PYH1_k127_4254779_1 PFAM Fibronectin type III domain - - - 0.000001955 62.0
PYH1_k127_4261048_0 Fumarase C C-terminus K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 546.0
PYH1_k127_4261048_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000001802 154.0
PYH1_k127_4261048_2 cytochrome c biogenesis protein K06196 - - 0.000000000000000000001899 108.0
PYH1_k127_4261048_3 cell redox homeostasis K12057,K22278 - 3.5.1.104 0.00000002112 68.0
PYH1_k127_4261048_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000009163 64.0
PYH1_k127_4261048_5 CARDB - - - 0.0009779 51.0
PYH1_k127_4299621_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 422.0
PYH1_k127_4299621_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000003941 202.0
PYH1_k127_4299621_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000001173 162.0
PYH1_k127_4299621_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00001043 51.0
PYH1_k127_4301929_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 546.0
PYH1_k127_4301929_1 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000001013 162.0
PYH1_k127_4301929_2 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000002716 110.0
PYH1_k127_4301929_3 PFAM GHMP kinase K06982 - 2.7.1.169 0.000006658 50.0
PYH1_k127_4342380_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.02e-300 932.0
PYH1_k127_4342380_1 ZPR1-related zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000009861 182.0
PYH1_k127_4342380_2 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000008446 182.0
PYH1_k127_4342380_3 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000005959 155.0
PYH1_k127_4342380_4 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.0000000000000000000000007029 113.0
PYH1_k127_4342380_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000211 100.0
PYH1_k127_4342380_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000007134 94.0
PYH1_k127_4342380_7 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000009913 76.0
PYH1_k127_4357023_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 525.0
PYH1_k127_4357023_1 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000001324 202.0
PYH1_k127_4357023_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000001126 179.0
PYH1_k127_4357023_3 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000000000000000009256 159.0
PYH1_k127_4357023_4 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000006722 131.0
PYH1_k127_4357023_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000004138 116.0
PYH1_k127_4357023_6 - - - - 0.000001283 56.0
PYH1_k127_4358335_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 4.279e-240 752.0
PYH1_k127_4358335_1 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 572.0
PYH1_k127_4377573_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 341.0
PYH1_k127_4377573_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 301.0
PYH1_k127_4377573_2 PFAM UDP-N-acetylglucosamine 2-epimerase K01791 GO:0003674,GO:0003824,GO:0008761,GO:0016853,GO:0016854,GO:0016857 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 286.0
PYH1_k127_4377573_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001825 228.0
PYH1_k127_4377573_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000002807 204.0
PYH1_k127_4377573_5 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000001533 194.0
PYH1_k127_4379376_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002639 269.0
PYH1_k127_4379376_1 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000007195 213.0
PYH1_k127_4379376_2 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000001008 198.0
PYH1_k127_4379376_3 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000002577 76.0
PYH1_k127_4403378_0 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000004891 149.0
PYH1_k127_4403378_1 Domain of unknown function DUF11 - - - 0.00000000007189 76.0
PYH1_k127_4441923_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
PYH1_k127_4441923_1 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000003836 203.0
PYH1_k127_4441923_2 UbiA prenyltransferase family K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000254 181.0
PYH1_k127_4441923_3 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000004756 138.0
PYH1_k127_4441923_4 - - - - 0.0000000000000000003849 93.0
PYH1_k127_4460441_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1061.0
PYH1_k127_4460441_1 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000000000000000000000000000000000000000000007177 188.0
PYH1_k127_4460724_0 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 460.0
PYH1_k127_4460724_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 316.0
PYH1_k127_4460724_2 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000003303 208.0
PYH1_k127_4460724_3 geranylgeranyl reductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000001941 173.0
PYH1_k127_4460724_4 cheY-homologous receiver domain - - - 0.00000000000000000000003005 113.0
PYH1_k127_4463459_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
PYH1_k127_4463459_1 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000009325 172.0
PYH1_k127_4463459_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000252 139.0
PYH1_k127_4463459_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000004118 98.0
PYH1_k127_4463459_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000002521 91.0
PYH1_k127_4489703_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003697 242.0
PYH1_k127_4489703_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000002358 199.0
PYH1_k127_4505894_0 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000001254 155.0
PYH1_k127_4505894_1 Belongs to the peptidase S8 family K13276 - - 0.000000000001784 78.0
PYH1_k127_4505894_2 It is involved in the biological process described with multicellular organismal development - GO:0001501,GO:0001558,GO:0001568,GO:0001667,GO:0001702,GO:0001944,GO:0002009,GO:0002011,GO:0003002,GO:0003007,GO:0003143,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0006928,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007275,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007413,GO:0007507,GO:0008037,GO:0008038,GO:0008150,GO:0008361,GO:0008589,GO:0009653,GO:0009719,GO:0009790,GO:0009792,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010646,GO:0010648,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0016043,GO:0016477,GO:0019219,GO:0019222,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030154,GO:0030182,GO:0030307,GO:0030326,GO:0030509,GO:0030516,GO:0031175,GO:0031323,GO:0031326,GO:0031344,GO:0031346,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032535,GO:0032879,GO:0035050,GO:0035107,GO:0035108,GO:0035113,GO:0035239,GO:0035295,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0042074,GO:0042221,GO:0043009,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045879,GO:0045927,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048565,GO:0048568,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048638,GO:0048639,GO:0048666,GO:0048699,GO:0048704,GO:0048705,GO:0048706,GO:0048729,GO:0048731,GO:0048736,GO:0048841,GO:0048842,GO:0048856,GO:0048869,GO:0048870,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050920,GO:0050921,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051179,GO:0051239,GO:0051240,GO:0051252,GO:0051270,GO:0051272,GO:0051674,GO:0051716,GO:0051960,GO:0051962,GO:0055113,GO:0055123,GO:0060173,GO:0060255,GO:0060284,GO:0060348,GO:0060349,GO:0060429,GO:0060562,GO:0060971,GO:0060972,GO:0060976,GO:0061371,GO:0061387,GO:0061564,GO:0065007,GO:0065008,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071772,GO:0071773,GO:0071840,GO:0071907,GO:0072358,GO:0072359,GO:0080090,GO:0090066,GO:0090504,GO:0097094,GO:0097155,GO:0106030,GO:0120035,GO:0120036,GO:1902667,GO:1902669,GO:1903506,GO:1904888,GO:2000026,GO:2000112,GO:2001141 - 0.0000000001123 76.0
PYH1_k127_4522358_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 404.0
PYH1_k127_4522358_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000005163 267.0
PYH1_k127_4522358_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000001017 223.0
PYH1_k127_4522358_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000006093 204.0
PYH1_k127_4522358_4 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.000000000000000000000001589 111.0
PYH1_k127_4522358_5 COG1522 Transcriptional regulators - - - 0.000001887 55.0
PYH1_k127_4534666_0 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000001298 215.0
PYH1_k127_4534666_1 Fcf1 K07158 - - 0.00000000000000000007974 94.0
PYH1_k127_4534666_2 - - - - 0.00000000001108 74.0
PYH1_k127_4554862_0 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000001679 173.0
PYH1_k127_4554862_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000003026 75.0
PYH1_k127_4561269_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 436.0
PYH1_k127_4561269_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 341.0
PYH1_k127_4561269_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 308.0
PYH1_k127_4561269_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000005017 154.0
PYH1_k127_4561269_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000001177 135.0
PYH1_k127_4561269_5 Tetratricopeptide repeat - - - 0.00000000000000000001412 98.0
PYH1_k127_4561269_7 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.0003338 46.0
PYH1_k127_4592353_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 317.0
PYH1_k127_4592353_1 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002823 180.0
PYH1_k127_4592353_2 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000001908 154.0
PYH1_k127_4592353_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000266 124.0
PYH1_k127_4592353_4 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000004277 121.0
PYH1_k127_4592353_5 Binds to the 23S rRNA K02885 - - 0.00005131 46.0
PYH1_k127_4612740_0 cellulase activity - - - 0.00000001925 68.0
PYH1_k127_461447_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 567.0
PYH1_k127_461447_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 366.0
PYH1_k127_461447_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 366.0
PYH1_k127_461447_3 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 355.0
PYH1_k127_461447_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 319.0
PYH1_k127_461447_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
PYH1_k127_461447_6 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000006096 136.0
PYH1_k127_4628022_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 2.766e-232 726.0
PYH1_k127_4628022_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 454.0
PYH1_k127_4628022_2 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 385.0
PYH1_k127_4628022_3 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001895 200.0
PYH1_k127_4628022_4 Hydrogenase maturation protease - - - 0.0000000000000000000001353 108.0
PYH1_k127_4629815_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.948e-251 794.0
PYH1_k127_4629815_1 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
PYH1_k127_4629815_2 snRNP Sm proteins K04796 - - 0.00000000000000000000001502 102.0
PYH1_k127_4629815_3 PFAM peptidase U32 K08303 - - 0.0000000000000005323 81.0
PYH1_k127_4629815_4 zinc-ribbon family - - - 0.0001757 51.0
PYH1_k127_4632204_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 418.0
PYH1_k127_4632204_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000001312 200.0
PYH1_k127_4634386_0 DoxX K16937 - 1.8.5.2 0.0004736 51.0
PYH1_k127_4642391_0 FAD binding domain K00803 - 2.5.1.26 0.0000000000000000000000000003498 125.0
PYH1_k127_4642391_1 Beta-lactamase - - - 0.0000000000000001061 92.0
PYH1_k127_4659258_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.0000000000000000000000000000000000000000000561 164.0
PYH1_k127_4659258_1 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000000000000000000000000000001347 126.0
PYH1_k127_4659258_2 Hep Hag repeat protein K01190,K01224 - 3.2.1.23,3.2.1.89 0.000000000000004025 88.0
PYH1_k127_4663436_0 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000002841 149.0
PYH1_k127_4663436_1 HAD-hyrolase-like - - - 0.0000000000000000000000000002978 125.0
PYH1_k127_4663436_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000002553 63.0
PYH1_k127_4715722_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 8.236e-240 770.0
PYH1_k127_4715722_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 328.0
PYH1_k127_4715722_2 Kef-type K transport systems, membrane components K03455 - - 0.0000000000000000000000000000000000000009333 164.0
PYH1_k127_4715722_3 PAC2 family K06869 - - 0.00000000000000000000000000000008983 128.0
PYH1_k127_4722994_0 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000072 84.0
PYH1_k127_4722994_1 protein conserved in archaea - - - 0.000000000000001006 86.0
PYH1_k127_4722994_2 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0004328 50.0
PYH1_k127_4748602_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 454.0
PYH1_k127_4752010_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 448.0
PYH1_k127_4752010_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001145 275.0
PYH1_k127_4752010_2 N-4 methylation of cytosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 267.0
PYH1_k127_4752010_3 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000002353 230.0
PYH1_k127_4752010_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000001107 203.0
PYH1_k127_4752010_5 EamA-like transporter family K07790 - - 0.0000000000000000000000000000000000000000000000000007225 197.0
PYH1_k127_4752010_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000002872 184.0
PYH1_k127_4752010_7 membrane transporter protein K07090 - - 0.00000000000000000036 97.0
PYH1_k127_4757856_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 421.0
PYH1_k127_4757856_1 Superoxide dismutase K00518 - 1.15.1.1 0.000000000000000000000000000000000000000005054 160.0
PYH1_k127_4757856_10 Peptidase S24-like - - - 0.000000000003768 78.0
PYH1_k127_4757856_2 DGC domain - - - 0.00000000000000000000000000000000008246 143.0
PYH1_k127_4757856_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000003431 133.0
PYH1_k127_4757856_4 OsmC-like protein - - - 0.0000000000000000000000000000003544 128.0
PYH1_k127_4757856_5 DGC domain - - - 0.00000000000000000000000004387 114.0
PYH1_k127_4757856_6 Oxidoreductase FAD-binding domain - - - 0.00000000000000000003244 94.0
PYH1_k127_4757856_7 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000003027 84.0
PYH1_k127_4757856_8 redox-active disulfide protein 2 - - - 0.00000000000000041 82.0
PYH1_k127_4757856_9 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.00000000000006798 74.0
PYH1_k127_4791227_0 Periplasmic copper-binding protein (NosD) - - - 0.0000216 57.0
PYH1_k127_4791227_1 Parallel beta-helix repeats - - - 0.00002849 57.0
PYH1_k127_4793003_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
PYH1_k127_4793003_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000003448 213.0
PYH1_k127_4793003_2 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000194 211.0
PYH1_k127_4793003_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000004416 168.0
PYH1_k127_4793003_4 to orf3 of fosmid clone 4B7mr3 - - - 0.00000000000000000002017 104.0
PYH1_k127_4793003_5 cellular modified histidine biosynthetic process - - - 0.00000000000000000002602 100.0
PYH1_k127_4803677_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002428 265.0
PYH1_k127_4803677_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
PYH1_k127_4803677_2 protein catabolic process K03420,K13525,K17681 - - 0.0000000000000000000000000000000000000000000000000001012 201.0
PYH1_k127_4803677_3 PRC-barrel domain - - - 0.00000000000000000001472 93.0
PYH1_k127_4803677_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000456 93.0
PYH1_k127_4803677_5 ABC-2 type transporter K01992 - - 0.000000000000000001535 95.0
PYH1_k127_4803677_6 - - - - 0.000000002433 68.0
PYH1_k127_4803677_7 5'-3' exoribonuclease activity K12574 - - 0.000005754 49.0
PYH1_k127_4803677_8 PFAM membrane-flanked domain - - - 0.0000421 53.0
PYH1_k127_4803677_9 Regulatory protein MarR - - - 0.0004101 50.0
PYH1_k127_4824347_0 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 425.0
PYH1_k127_4824347_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007839 224.0
PYH1_k127_4824347_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000007715 149.0
PYH1_k127_4824347_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000005035 127.0
PYH1_k127_4824347_4 4 iron, 4 sulfur cluster binding K00205,K02573 - - 0.000000000000000000000004476 116.0
PYH1_k127_4824347_5 - - - - 0.0000000000000000000003606 102.0
PYH1_k127_4824347_6 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000002771 86.0
PYH1_k127_4824347_7 DNA alkylation repair enzyme - - - 0.0000000000004944 78.0
PYH1_k127_4824347_8 - - - - 0.0005076 46.0
PYH1_k127_4824347_9 SnoaL-like polyketide cyclase K07255 - - 0.0006974 53.0
PYH1_k127_4836332_0 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 544.0
PYH1_k127_4836332_1 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000002122 188.0
PYH1_k127_4890201_0 photosynthesis - - - 0.0000000000000000000000000000000000003754 157.0
PYH1_k127_4890201_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000276 133.0
PYH1_k127_4890201_2 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0008829 51.0
PYH1_k127_4908549_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 471.0
PYH1_k127_4908549_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 327.0
PYH1_k127_4908549_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000001474 142.0
PYH1_k127_4915412_0 COG3209 Rhs family protein - - - 0.00000000000000137 91.0
PYH1_k127_4915780_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 377.0
PYH1_k127_4915780_1 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000006033 224.0
PYH1_k127_4915780_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000005644 161.0
PYH1_k127_4915780_3 glutamine amidotransferase - - - 0.0000000008437 69.0
PYH1_k127_4938686_0 Wd40 repeat-containing protein - - - 0.0000000000000000000000000000000000000000006107 174.0
PYH1_k127_4938686_1 COG1520 FOG WD40-like repeat - - - 0.0000000002834 69.0
PYH1_k127_4938686_2 Defective in exine formation - - - 0.000000001574 70.0
PYH1_k127_4970639_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000004466 78.0
PYH1_k127_4999488_0 PFAM Histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 332.0
PYH1_k127_4999488_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000000674 205.0
PYH1_k127_4999488_2 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000005684 137.0
PYH1_k127_4999488_3 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000224 107.0
PYH1_k127_4999488_4 Transcriptional regulator K05804,K13652,K13653 - - 0.000000000000000568 93.0
PYH1_k127_5002016_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000003989 166.0
PYH1_k127_5002016_1 Protein conserved in bacteria K07192 - - 0.0004125 51.0
PYH1_k127_5008910_0 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000005561 137.0
PYH1_k127_5008910_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000009912 107.0
PYH1_k127_5016315_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.222e-244 779.0
PYH1_k127_5016315_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 289.0
PYH1_k127_5029814_0 Belongs to the complex I 49 kDa subunit family K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 372.0
PYH1_k127_5029814_1 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05572 GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000002243 205.0
PYH1_k127_5029814_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000003791 179.0
PYH1_k127_5029814_3 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000005104 125.0
PYH1_k127_5029814_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3 0.00000000000001358 78.0
PYH1_k127_5057623_0 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 340.0
PYH1_k127_5057623_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000007067 234.0
PYH1_k127_5057623_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001127 222.0
PYH1_k127_5057623_3 PFAM Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000006648 97.0
PYH1_k127_5057623_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000008804 64.0
PYH1_k127_5078377_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000009 200.0
PYH1_k127_5078377_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000005195 159.0
PYH1_k127_5078377_2 TfoX N-terminal domain - - - 0.000000000000000000001054 99.0
PYH1_k127_5078377_3 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000007268 72.0
PYH1_k127_5078377_4 Bacteriocin-protection protein - - - 0.00000007658 55.0
PYH1_k127_5084452_0 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000003559 169.0
PYH1_k127_5084452_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000131 132.0
PYH1_k127_5084452_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000003143 79.0
PYH1_k127_5119758_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 393.0
PYH1_k127_5119758_1 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000007561 96.0
PYH1_k127_5119758_2 Acetyltransferase (GNAT) domain - - - 0.0000000003041 67.0
PYH1_k127_5132767_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000006419 75.0
PYH1_k127_5132767_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000001703 69.0
PYH1_k127_5132767_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000001414 66.0
PYH1_k127_5132767_3 PFAM SpoVT AbrB K07172 - - 0.0001075 47.0
PYH1_k127_5132767_4 Dodecin K09165 - - 0.00026 50.0
PYH1_k127_5137651_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
PYH1_k127_5137651_1 metaphase/anaphase transition of mitotic cell cycle K03350 GO:0000003,GO:0000070,GO:0000151,GO:0000152,GO:0000209,GO:0000278,GO:0000280,GO:0000375,GO:0000377,GO:0000398,GO:0000819,GO:0001775,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005680,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006396,GO:0006397,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007091,GO:0007275,GO:0007338,GO:0007343,GO:0007346,GO:0007389,GO:0008150,GO:0008152,GO:0008283,GO:0008356,GO:0008380,GO:0009056,GO:0009057,GO:0009504,GO:0009566,GO:0009653,GO:0009719,GO:0009725,GO:0009733,GO:0009790,GO:0009791,GO:0009793,GO:0009798,GO:0009888,GO:0009896,GO:0009933,GO:0009948,GO:0009949,GO:0009952,GO:0009987,GO:0010014,GO:0010015,GO:0010033,GO:0010071,GO:0010154,GO:0010467,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0015630,GO:0016043,GO:0016070,GO:0016071,GO:0016192,GO:0016567,GO:0016740,GO:0017156,GO:0019538,GO:0019787,GO:0019899,GO:0019902,GO:0019903,GO:0019941,GO:0019953,GO:0022402,GO:0022414,GO:0022622,GO:0030071,GO:0030154,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034641,GO:0036211,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044784,GO:0045055,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0046483,GO:0046903,GO:0048285,GO:0048316,GO:0048364,GO:0048507,GO:0048508,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048532,GO:0048608,GO:0048731,GO:0048829,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051247,GO:0051276,GO:0051301,GO:0051603,GO:0051704,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0060467,GO:0060468,GO:0060471,GO:0061458,GO:0061630,GO:0061659,GO:0062033,GO:0065001,GO:0065007,GO:0070013,GO:0070647,GO:0070979,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0080154,GO:0090068,GO:0090304,GO:0090421,GO:0097159,GO:0098813,GO:0099402,GO:0140014,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905392,GO:1905818,GO:1905820,GO:1990234,GO:2000241,GO:2000242,GO:2001252 - 0.000007043 55.0
PYH1_k127_5138381_0 conserved repeat domain protein - - - 0.0000000000000000000001534 115.0
PYH1_k127_5144664_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000002753 93.0
PYH1_k127_5144664_1 Transglutaminase-like superfamily - - - 0.000000000000003606 89.0
PYH1_k127_5162023_0 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000009617 235.0
PYH1_k127_5162023_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000121 225.0
PYH1_k127_5162023_2 protein conserved in archaea - - - 0.00000000000000000000001936 108.0
PYH1_k127_5193245_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.736e-226 722.0
PYH1_k127_5193245_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 349.0
PYH1_k127_5193245_10 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.000000000000000000008923 99.0
PYH1_k127_5193245_11 binds to the 23S rRNA K02921 - - 0.0000000000000000002583 100.0
PYH1_k127_5193245_12 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000000007056 69.0
PYH1_k127_5193245_13 Transcription factor Pcc1 K09741 - - 0.0000002415 58.0
PYH1_k127_5193245_14 Roadblock/LC7 domain K07131 - - 0.00004683 51.0
PYH1_k127_5193245_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 320.0
PYH1_k127_5193245_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000005241 254.0
PYH1_k127_5193245_4 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
PYH1_k127_5193245_5 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000003543 209.0
PYH1_k127_5193245_6 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000002986 168.0
PYH1_k127_5193245_7 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000003969 152.0
PYH1_k127_5193245_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000003539 138.0
PYH1_k127_5193245_9 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000485 127.0
PYH1_k127_5209922_0 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 350.0
PYH1_k127_5209922_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 308.0
PYH1_k127_5209922_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000001378 239.0
PYH1_k127_5209922_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000001936 157.0
PYH1_k127_5209922_4 COG3291 FOG PKD repeat - - - 0.00000145 60.0
PYH1_k127_5209922_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0001095 50.0
PYH1_k127_5211282_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.083e-215 695.0
PYH1_k127_5211282_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 349.0
PYH1_k127_5211282_2 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000002949 114.0
PYH1_k127_5211282_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000002839 82.0
PYH1_k127_5236123_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 345.0
PYH1_k127_5325253_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 321.0
PYH1_k127_5325253_1 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006836 267.0
PYH1_k127_533094_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 385.0
PYH1_k127_5336126_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 382.0
PYH1_k127_5336126_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 390.0
PYH1_k127_5336126_2 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000009719 166.0
PYH1_k127_5336126_3 Belongs to the UPF0145 family - - - 0.000000000000000000000000004814 114.0
PYH1_k127_5336126_4 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000009566 95.0
PYH1_k127_5368500_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 472.0
PYH1_k127_5368500_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 357.0
PYH1_k127_5368500_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 304.0
PYH1_k127_5368500_3 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000002311 204.0
PYH1_k127_5458185_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 519.0
PYH1_k127_5458185_1 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000002113 203.0
PYH1_k127_5458185_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000001333 129.0
PYH1_k127_5458185_3 FG-GAP repeat - - - 0.000000000000000000005611 111.0
PYH1_k127_5458185_4 Fibronectin type III domain - - - 0.00000000000000000203 100.0
PYH1_k127_5458185_5 - - - - 0.00000000000002551 72.0
PYH1_k127_5458185_6 Esterase PHB depolymerase - - - 0.000004169 60.0
PYH1_k127_5458185_7 Putative Ig domain - - - 0.0002156 56.0
PYH1_k127_5458185_8 Outer membrane protein, OmpA MotB, C-terminal - - - 0.0003735 55.0
PYH1_k127_5475144_0 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000000000002319 219.0
PYH1_k127_5475144_1 Transcriptional regulator K07108 - - 0.0000000001414 68.0
PYH1_k127_5475144_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00001551 48.0
PYH1_k127_5484941_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003406 267.0
PYH1_k127_5484941_1 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000029 205.0
PYH1_k127_5484941_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000001102 212.0
PYH1_k127_5484941_3 - - - - 0.000000000000000000000000000000000000000000000000000007006 214.0
PYH1_k127_5484941_4 ParB-like nuclease domain - - - 0.000000000000000000008899 95.0
PYH1_k127_5484941_5 Low molecular weight phosphotyrosine protein phosphatase K03325,K03741 - 1.20.4.1 0.000000000000000001456 91.0
PYH1_k127_5484941_6 OB-fold nucleic acid binding domain - - - 0.0003575 48.0
PYH1_k127_5507180_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.074e-209 662.0
PYH1_k127_5507180_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000002853 246.0
PYH1_k127_5507180_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000008535 97.0
PYH1_k127_5507180_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000001635 57.0
PYH1_k127_5512914_0 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 358.0
PYH1_k127_5512914_1 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000005465 203.0
PYH1_k127_5537900_0 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000002164 262.0
PYH1_k127_5537900_1 - - - - 0.00000000000000000000000000000000000000000000000003714 188.0
PYH1_k127_5601900_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 443.0
PYH1_k127_5601900_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000007069 140.0
PYH1_k127_5601900_2 AAA ATPase domain - - - 0.000426 53.0
PYH1_k127_5601900_4 SCP-2 sterol transfer family - - - 0.0008164 48.0
PYH1_k127_5611358_0 OmpA family - - - 0.000000000002154 81.0
PYH1_k127_5638656_0 COG1012 NAD-dependent aldehyde dehydrogenases K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 491.0
PYH1_k127_5638656_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000007181 212.0
PYH1_k127_5643279_0 Protein of unknown function (DUF3494) - - - 0.00000000000000000000003623 116.0
PYH1_k127_5646814_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 335.0
PYH1_k127_5646814_1 Protein of unknown function TPD sequence-motif - - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
PYH1_k127_5646814_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000002035 174.0
PYH1_k127_5646814_3 ribonuclease activity K07060 - - 0.0000000000000000000000000000000135 132.0
PYH1_k127_5646814_4 - K21029 - 2.7.7.80 0.000432 51.0
PYH1_k127_5668471_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 605.0
PYH1_k127_5668471_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 344.0
PYH1_k127_5668471_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001448 246.0
PYH1_k127_5668471_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000007301 130.0
PYH1_k127_5668471_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000006561 123.0
PYH1_k127_5668471_5 von Willebrand factor, type A K07114 - - 0.000000000000000000000001839 120.0
PYH1_k127_5668471_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000001689 100.0
PYH1_k127_5668471_7 FHA domain containing protein - - - 0.0000000003461 73.0
PYH1_k127_5668471_8 peptidase M36 K01417 - - 0.000005023 60.0
PYH1_k127_5668471_9 repeat protein - - - 0.00002335 57.0
PYH1_k127_5742963_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 390.0
PYH1_k127_5742963_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000006265 235.0
PYH1_k127_5742963_2 Fic/DOC family - - - 0.00000000000000000000000000000000007923 145.0
PYH1_k127_5796981_0 PKD domain - - - 0.00000000000000000000000000000272 140.0
PYH1_k127_5796981_1 - - - - 0.0000000001452 69.0
PYH1_k127_5804385_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1041.0
PYH1_k127_5804385_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 375.0
PYH1_k127_5804385_2 hydrolase, family 25 - - - 0.000000000000002762 90.0
PYH1_k127_5811352_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 451.0
PYH1_k127_5811352_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000005118 173.0
PYH1_k127_5811352_2 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.0000000000000000000000001217 116.0
PYH1_k127_5811352_3 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000003123 87.0
PYH1_k127_5811352_4 archaeal Zn-finger protein - - - 0.00000000000002433 81.0
PYH1_k127_5838859_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 459.0
PYH1_k127_5838859_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 413.0
PYH1_k127_5838859_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 375.0
PYH1_k127_5838859_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
PYH1_k127_5869362_0 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000003734 158.0
PYH1_k127_5869362_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000006148 148.0
PYH1_k127_5869362_2 PFAM MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000001783 117.0
PYH1_k127_5869362_3 Protein of unknown function (DUF1616) - - - 0.000000000000000000005244 102.0
PYH1_k127_5869362_4 KaiC - - - 0.00000000000000000685 94.0
PYH1_k127_5869362_5 RNase_H superfamily K07502 - - 0.00000000000001256 75.0
PYH1_k127_5908398_0 Belongs to the enoyl-CoA hydratase isomerase family K15016 - 1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 561.0
PYH1_k127_5908398_1 synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 400.0
PYH1_k127_5908398_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000001592 183.0
PYH1_k127_5908398_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000008318 59.0
PYH1_k127_5918249_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000006571 239.0
PYH1_k127_5918249_1 Isochorismatase family - - - 0.00000000004232 64.0
PYH1_k127_5918249_2 helix_turn_helix, mercury resistance - - - 0.00003266 51.0
PYH1_k127_5976979_0 Type II/IV secretion system protein K07332 - - 6.607e-226 714.0
PYH1_k127_5976979_1 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 359.0
PYH1_k127_5976979_2 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006533 261.0
PYH1_k127_5976979_3 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000002752 212.0
PYH1_k127_5976979_4 Double zinc ribbon - - - 0.0000000000000000000000000000003451 145.0
PYH1_k127_5976979_5 CARDB - - - 0.00000000026 76.0
PYH1_k127_5998640_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 293.0
PYH1_k127_5998640_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004544 242.0
PYH1_k127_5998640_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
PYH1_k127_5998640_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000009784 218.0
PYH1_k127_5998640_4 Acetyl xylan esterase (AXE1) - - - 0.0000000000000002247 92.0
PYH1_k127_5998640_5 membrane-associated protein domain - - - 0.000007176 55.0
PYH1_k127_6022537_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000003957 210.0
PYH1_k127_6022537_1 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000000000000000000000000000000000000002429 184.0
PYH1_k127_6022537_3 PFAM PKD domain containing protein - - - 0.0000001519 64.0
PYH1_k127_6022537_4 - - - - 0.00001312 54.0
PYH1_k127_6031621_0 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000002429 216.0
PYH1_k127_6031621_1 COG1361 S-layer domain - - - 0.00000001296 66.0
PYH1_k127_6076962_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 412.0
PYH1_k127_6076962_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000002469 213.0
PYH1_k127_6076962_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000007163 134.0
PYH1_k127_6076962_3 Male sterility protein K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000008421 55.0
PYH1_k127_6104298_0 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000005305 117.0
PYH1_k127_6104298_1 formylmethanofuran dehydrogenase, subunit E - - - 0.00000000000002526 84.0
PYH1_k127_6104298_2 metallocarboxypeptidase activity K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.00000003498 66.0
PYH1_k127_6104298_3 Bacterial transcriptional activator domain - - - 0.00008421 55.0
PYH1_k127_6207001_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 331.0
PYH1_k127_6207001_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000002429 160.0
PYH1_k127_6207001_2 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000003241 146.0
PYH1_k127_6207001_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000002741 91.0
PYH1_k127_6207001_4 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000004112 77.0
PYH1_k127_6207001_5 Glycosyl transferase family 41 - - - 0.000003951 54.0
PYH1_k127_6215634_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000005188 216.0
PYH1_k127_624245_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 517.0
PYH1_k127_624245_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000002392 195.0
PYH1_k127_6260604_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 566.0
PYH1_k127_6260604_1 Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000003712 183.0
PYH1_k127_6260604_2 TM2 domain - - - 0.000001271 57.0
PYH1_k127_6275018_0 Ras of Complex, Roc, domain of DAPkinase - - - 0.00000000000000000000001206 110.0
PYH1_k127_6275018_2 - - - - 0.000000000000000007597 86.0
PYH1_k127_6275018_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000005648 83.0
PYH1_k127_6275018_5 Major facilitator Superfamily K07552,K19577 - - 0.0003471 53.0
PYH1_k127_6311779_0 Peptidase family M3 K01392 - 3.4.24.15 2.389e-203 654.0
PYH1_k127_6311779_1 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 484.0
PYH1_k127_6311779_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002936 254.0
PYH1_k127_6311779_3 Daunorubicin resistance abc transporter atpase subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000001265 241.0
PYH1_k127_6311779_4 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000003326 168.0
PYH1_k127_6311779_5 ADP-ribose pyrophosphatase K03574 - 3.6.1.55 0.0000000000000000000000000004993 130.0
PYH1_k127_6311779_6 PFAM regulatory protein, ArsR - - - 0.00000000000127 77.0
PYH1_k127_6312467_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003146 278.0
PYH1_k127_6312467_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000001442 184.0
PYH1_k127_6312467_2 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000001267 113.0
PYH1_k127_6312467_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00001155 48.0
PYH1_k127_6336051_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 349.0
PYH1_k127_6336051_1 AAA domain - - - 0.000000000000000000000000000000000000000002012 166.0
PYH1_k127_6336051_2 exosome subunit K07581 - - 0.0000000000000000000000007286 109.0
PYH1_k127_6336051_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000001427 120.0
PYH1_k127_6336051_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002798 54.0
PYH1_k127_6354415_0 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001526 279.0
PYH1_k127_6354415_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000004508 189.0
PYH1_k127_6386196_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000003625 276.0
PYH1_k127_6386196_1 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000003607 85.0
PYH1_k127_6386196_2 - - - - 0.00000005062 56.0
PYH1_k127_6434356_0 - - - - 0.000000000000000000000000000000000000007059 150.0
PYH1_k127_6434356_1 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000909 127.0
PYH1_k127_6434356_2 Pfam:DUF552 K09152 - - 0.0000000000000000000000001457 111.0
PYH1_k127_6434356_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000006125 81.0
PYH1_k127_6469844_0 COG1233 Phytoene dehydrogenase and related proteins K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 589.0
PYH1_k127_6469844_1 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 296.0
PYH1_k127_6469844_2 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases K20616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004354 265.0
PYH1_k127_6469844_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000003818 143.0
PYH1_k127_6469844_4 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000002585 126.0
PYH1_k127_6478597_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
PYH1_k127_6478597_1 deoxyribonuclease I activity K06131,K06915 - - 0.00000000000000000000000000000000000000000000003982 184.0
PYH1_k127_6478597_2 Peptidase C13 family - - - 0.0000000000000000000000002192 115.0
PYH1_k127_6492007_0 DNA polymerase type-B family K02319 - 2.7.7.7 4.225e-272 860.0
PYH1_k127_6492007_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000007948 67.0
PYH1_k127_6492007_2 Belongs to the carbohydrate kinase PfkB family - - - 0.0000000001496 72.0
PYH1_k127_6497969_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 493.0
PYH1_k127_6497969_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000844 204.0
PYH1_k127_6497969_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000171 139.0
PYH1_k127_6522894_0 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000005471 213.0
PYH1_k127_6522894_1 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000001103 197.0
PYH1_k127_6522894_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000004465 136.0
PYH1_k127_6522894_3 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000002055 102.0
PYH1_k127_6522894_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000001301 73.0
PYH1_k127_6522894_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000761 63.0
PYH1_k127_6581733_0 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 374.0
PYH1_k127_6581733_1 L-threonine 3-dehydrogenase - - - 0.0000418 49.0
PYH1_k127_6597415_0 - - - - 0.0000000000000000000000000000000000000000001119 171.0
PYH1_k127_6597415_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000002574 147.0
PYH1_k127_6597415_2 glucose sorbosone - - - 0.000003652 59.0
PYH1_k127_6630837_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 321.0
PYH1_k127_6630837_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000006611 106.0
PYH1_k127_6638537_0 methylthiotransferase activity K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 349.0
PYH1_k127_6659963_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007706 289.0
PYH1_k127_6659963_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000007461 248.0
PYH1_k127_667530_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 339.0
PYH1_k127_667530_1 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000006418 248.0
PYH1_k127_667530_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000007336 229.0
PYH1_k127_667530_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0003625 53.0
PYH1_k127_6689417_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 321.0
PYH1_k127_6689417_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008728 270.0
PYH1_k127_6689417_2 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000004259 207.0
PYH1_k127_6689417_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000000005096 119.0
PYH1_k127_6689417_4 Phosphate transport regulator K07220 - - 0.000000000000000000001126 103.0
PYH1_k127_6689417_5 Belongs to the ABC transporter superfamily K02052 - - 0.0000621 48.0
PYH1_k127_671326_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
PYH1_k127_671326_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000005045 187.0
PYH1_k127_671326_2 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000001775 121.0
PYH1_k127_6724529_0 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000003822 181.0
PYH1_k127_6724529_1 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000001588 140.0
PYH1_k127_6724529_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000007462 70.0
PYH1_k127_6764521_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000004758 217.0
PYH1_k127_6764521_1 ThiF family K12164 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008641,GO:0009987,GO:0016874,GO:0016877,GO:0019538,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070647,GO:0071566,GO:0071569,GO:0071704,GO:1901564 - 0.0000000000000000000000000000007701 128.0
PYH1_k127_6764521_2 Arsenical pump membrane protein - - - 0.000000000000000000000000000004207 125.0
PYH1_k127_6764521_3 - - - - 0.0000000000000000000009856 98.0
PYH1_k127_6764521_4 SPFH domain-Band 7 family - - - 0.00003354 53.0
PYH1_k127_6765052_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000001098 210.0
PYH1_k127_6765052_1 sequence-specific DNA binding - - - 0.0000001764 57.0
PYH1_k127_6782739_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 492.0
PYH1_k127_6782739_1 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 430.0
PYH1_k127_6782739_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000002033 189.0
PYH1_k127_6782739_3 ATPases associated with a variety of cellular activities K09013 - - 0.0000000000000004046 78.0
PYH1_k127_6782739_4 UFM1 transferase activity K12165 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031624,GO:0032446,GO:0033554,GO:0034976,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044390,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070647,GO:0071568,GO:0071569,GO:0071704,GO:0140096,GO:1901564,GO:1990564,GO:1990592 - 0.00003176 53.0
PYH1_k127_6796431_0 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000000000000000009899 109.0
PYH1_k127_681657_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 319.0
PYH1_k127_681657_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 301.0
PYH1_k127_681657_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001824 282.0
PYH1_k127_681657_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001779 269.0
PYH1_k127_681657_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000007826 74.0
PYH1_k127_6854351_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 492.0
PYH1_k127_6876366_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 449.0
PYH1_k127_6876366_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 382.0
PYH1_k127_6876366_2 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000000007099 156.0
PYH1_k127_6876366_3 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000002246 115.0
PYH1_k127_6876366_4 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins K03113 - - 0.000000000000000000001853 98.0
PYH1_k127_6882863_0 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000006748 241.0
PYH1_k127_6882863_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
PYH1_k127_6898996_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 515.0
PYH1_k127_6898996_1 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 335.0
PYH1_k127_6898996_2 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 294.0
PYH1_k127_6898996_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000004471 190.0
PYH1_k127_6898996_4 AIR carboxylase K06898 - - 0.000000000000008445 81.0
PYH1_k127_6940764_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 422.0
PYH1_k127_6940764_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 426.0
PYH1_k127_6940764_2 membrane - - - 0.000000000001537 82.0
PYH1_k127_6940764_3 Glycosyltransferase Family 4 - - - 0.00005876 49.0
PYH1_k127_6942017_0 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000006418 233.0
PYH1_k127_6942017_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000601 175.0
PYH1_k127_6942017_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000006614 125.0
PYH1_k127_6944662_0 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000177 231.0
PYH1_k127_6944662_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000002106 188.0
PYH1_k127_6944662_2 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000006185 166.0
PYH1_k127_6944662_3 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000004257 102.0
PYH1_k127_6944662_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001207 86.0
PYH1_k127_6944662_5 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000008493 92.0
PYH1_k127_6944662_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000001261 65.0
PYH1_k127_6944662_7 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000074 65.0
PYH1_k127_6971254_0 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003024 226.0
PYH1_k127_6971254_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000002421 221.0
PYH1_k127_6980921_0 acyl-CoA dehydrogenase activity K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 368.0
PYH1_k127_6980921_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000005933 213.0
PYH1_k127_6980921_2 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000002488 197.0
PYH1_k127_6980921_3 Sugar (and other) transporter - - - 0.0008324 47.0
PYH1_k127_7019551_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 557.0
PYH1_k127_7019551_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000001332 73.0
PYH1_k127_705064_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000193 287.0
PYH1_k127_705064_1 - - - - 0.0000000000000000000000000000002555 130.0
PYH1_k127_7051740_0 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 453.0
PYH1_k127_7051740_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000003072 71.0
PYH1_k127_7051740_2 COG2133 Glucose sorbosone dehydrogenases - - - 0.00007754 53.0
PYH1_k127_7055951_0 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000006541 233.0
PYH1_k127_7055951_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000005952 221.0
PYH1_k127_7055951_2 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000001315 95.0
PYH1_k127_7055951_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000001548 76.0
PYH1_k127_7055951_4 COG0517 FOG CBS domain - - - 0.000000000005016 78.0
PYH1_k127_705914_0 - - - - 0.0000000000000000000000000000000000000000000000000001154 209.0
PYH1_k127_7063670_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01620 - 2.3.1.29,2.3.1.47,4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 422.0
PYH1_k127_7063670_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 351.0
PYH1_k127_7063670_2 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 349.0
PYH1_k127_7063670_3 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000001994 181.0
PYH1_k127_7063670_4 homolog of gamma-carboxymuconolactone decarboxylase subunit - - - 0.00000000000000000000000000000000000000000000003148 172.0
PYH1_k127_7063670_5 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000001321 113.0
PYH1_k127_7063670_6 transcriptional - - - 0.0000000000000000000001334 100.0
PYH1_k127_7063670_7 Alpha beta hydrolase - - - 0.000000000000000001038 97.0
PYH1_k127_7063670_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000001518 85.0
PYH1_k127_7063670_9 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000002907 71.0
PYH1_k127_7088473_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 323.0
PYH1_k127_7088473_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008755 256.0
PYH1_k127_7088473_2 Nucleotidyltransferase domain K07076 - - 0.000000000000000009459 89.0
PYH1_k127_7088473_3 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.000000000007201 69.0
PYH1_k127_7092053_0 DEAD/H associated K03724 - - 3.1e-267 850.0
PYH1_k127_7092053_1 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001877 267.0
PYH1_k127_7092053_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000007464 132.0
PYH1_k127_7092053_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.000000000000004422 83.0
PYH1_k127_7092053_4 Sugar-specific transcriptional regulator TrmB - - - 0.0007466 49.0
PYH1_k127_710446_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.146e-236 743.0
PYH1_k127_710446_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000001082 217.0
PYH1_k127_710446_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000002782 135.0
PYH1_k127_710446_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000005583 78.0
PYH1_k127_717278_0 Oxidoreductase domain protein K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 304.0
PYH1_k127_717278_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 312.0
PYH1_k127_717278_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
PYH1_k127_717278_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
PYH1_k127_7180833_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 336.0
PYH1_k127_7180833_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 261.0
PYH1_k127_7180833_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000002897 243.0
PYH1_k127_7180833_3 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000009075 173.0
PYH1_k127_7180833_4 Methyltransferase type 12 - - - 0.0000000000000000000000017 113.0
PYH1_k127_7180833_5 PKD domain - - - 0.000000000000000000001003 111.0
PYH1_k127_7180833_6 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000004706 100.0
PYH1_k127_7180833_8 Domain of unknown function (DUF4082) - - - 0.00000000007022 77.0
PYH1_k127_7180833_9 self proteolysis - - - 0.000000129 65.0
PYH1_k127_7187354_0 Domain of unknown function (DUF1877) - - - 0.0000000000000000000005444 112.0
PYH1_k127_7187354_1 CarboxypepD_reg-like domain - - - 0.00000000005924 76.0
PYH1_k127_7187354_2 GXGXG motif - - - 0.000000001159 59.0
PYH1_k127_7189254_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000002199 195.0
PYH1_k127_7189254_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000003323 190.0
PYH1_k127_7189254_2 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000001224 162.0
PYH1_k127_7189254_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000004106 134.0
PYH1_k127_7189254_4 SnoaL-like polyketide cyclase - - - 0.000000000000000008646 87.0
PYH1_k127_7189254_5 - - - - 0.00001736 49.0
PYH1_k127_7206284_0 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 302.0
PYH1_k127_7206284_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000009402 206.0
PYH1_k127_7206284_2 Protein phosphatase 2C K17500 - 3.1.3.16 0.00000000000000002417 88.0
PYH1_k127_7206284_3 PFAM transcriptional regulator TrmB - - - 0.000000000003113 76.0
PYH1_k127_7233990_0 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 383.0
PYH1_k127_7233990_1 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 310.0
PYH1_k127_7233990_2 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000001602 134.0
PYH1_k127_7263493_0 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000005236 159.0
PYH1_k127_7263493_1 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000221 118.0
PYH1_k127_7263493_2 ubiE/COQ5 methyltransferase family - - - 0.000001225 60.0
PYH1_k127_726352_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000005441 101.0
PYH1_k127_7264011_0 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000486 84.0
PYH1_k127_7264011_1 InterPro IPR011467 - - - 0.00000001546 64.0
PYH1_k127_7264011_2 Short C-terminal domain K08982 - - 0.0000001901 54.0
PYH1_k127_7288697_0 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000005634 176.0
PYH1_k127_7288697_1 TPR Domain containing protein - - - 0.0000000000000000000000000000000001084 139.0
PYH1_k127_7288697_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000004112 126.0
PYH1_k127_7288697_3 protein conserved in archaea - - - 0.0000000000004864 83.0
PYH1_k127_7288697_4 TIGRFAM RHS repeat-associated core domain - - - 0.000000001097 72.0
PYH1_k127_7290087_0 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004722 286.0
PYH1_k127_7290087_1 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002074 178.0
PYH1_k127_7290087_2 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000007414 174.0
PYH1_k127_7290087_3 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000002798 92.0
PYH1_k127_72941_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 439.0
PYH1_k127_7307228_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 427.0
PYH1_k127_7307228_1 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000001514 150.0
PYH1_k127_7307228_2 Sulfurtransferase TusA - - - 0.00000000000000000000000003875 109.0
PYH1_k127_7307228_3 regulatory protein, arsR K07755,K21903 - 2.1.1.137 0.00000000000000002793 85.0
PYH1_k127_7307228_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000004779 71.0
PYH1_k127_7318611_0 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000005839 82.0
PYH1_k127_7318611_2 Bacterial transcriptional activator domain - - - 0.000369 46.0
PYH1_k127_7359609_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.004e-259 822.0
PYH1_k127_7359609_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 505.0
PYH1_k127_7359609_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000001872 234.0
PYH1_k127_7359609_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000008118 97.0
PYH1_k127_7366349_0 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 434.0
PYH1_k127_7366349_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003332 232.0
PYH1_k127_7366349_2 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000001348 184.0
PYH1_k127_7366349_3 FR47-like protein K03789 - 2.3.1.128 0.0000000000000811 78.0
PYH1_k127_7366349_4 - - - - 0.0000000000005342 78.0
PYH1_k127_7366349_5 deoxyhypusine monooxygenase activity - - - 0.00000000002983 72.0
PYH1_k127_7376815_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000002384 78.0
PYH1_k127_7376815_1 Domain of unknown function (DUF4347) - - - 0.00000008756 65.0
PYH1_k127_7380996_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 431.0
PYH1_k127_7400499_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 546.0
PYH1_k127_7468571_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 8.545e-215 676.0
PYH1_k127_7468571_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000005482 74.0
PYH1_k127_7477507_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006763 257.0
PYH1_k127_7477507_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000002028 242.0
PYH1_k127_7477507_2 transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000101 247.0
PYH1_k127_7477507_3 - - - - 0.0000000000000002594 81.0
PYH1_k127_7477507_4 pfam nudix - - - 0.00000000000001423 84.0
PYH1_k127_7477507_5 Acetyltransferase (GNAT) domain - - - 0.000005109 55.0
PYH1_k127_7512993_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 377.0
PYH1_k127_751557_0 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 307.0
PYH1_k127_751557_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000003987 250.0
PYH1_k127_751557_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000002239 235.0
PYH1_k127_751557_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000004028 221.0
PYH1_k127_7545450_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.779e-296 922.0
PYH1_k127_7545450_1 acetyl-CoA hydrolase transferase - - - 1.395e-207 661.0
PYH1_k127_7545450_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 325.0
PYH1_k127_7545450_3 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 312.0
PYH1_k127_7545450_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001158 289.0
PYH1_k127_7545450_5 methyltransferase K13311,K13326,K21335 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 0.00000000000000000000000000000000000000000000000000000000000009085 223.0
PYH1_k127_7545450_6 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000000456 138.0
PYH1_k127_7545450_7 transcriptional regulators - - - 0.00000000000000000005389 94.0
PYH1_k127_7547261_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 4.536e-222 703.0
PYH1_k127_7547261_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 273.0
PYH1_k127_7547261_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000002933 106.0
PYH1_k127_7547261_3 Exonuclease - - - 0.000001012 55.0
PYH1_k127_7547261_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000029 58.0
PYH1_k127_755133_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 415.0
PYH1_k127_755133_1 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 397.0
PYH1_k127_755133_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000001472 226.0
PYH1_k127_755133_3 aminopeptidase - - - 0.0000000000000000000000000000000000000000000004638 179.0
PYH1_k127_755133_4 vacuolar iron transporter - GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006828,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015318,GO:0016020,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030026,GO:0031090,GO:0034220,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055071,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0097577,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098805 - 0.0000000000000000000000000125 118.0
PYH1_k127_755133_5 Roadblock LC7 family protein K07131 - - 0.0000000000009715 73.0
PYH1_k127_755133_6 Acid phosphatase homologues - - - 0.00000000000103 73.0
PYH1_k127_7565328_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000354 274.0
PYH1_k127_7565328_1 COGs COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000001179 181.0
PYH1_k127_7565328_2 - - - - 0.000000000000000000000000000000000000000001803 160.0
PYH1_k127_7565328_3 - - - - 0.0000000000000009519 82.0
PYH1_k127_7565328_4 PFAM TspO MBR family K05770 - - 0.0000000000005848 78.0
PYH1_k127_7571711_0 Caspase domain - - - 0.0000000000000000000000003252 122.0
PYH1_k127_7571711_1 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000001266 91.0
PYH1_k127_7578140_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 372.0
PYH1_k127_7578140_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004237 260.0
PYH1_k127_7578140_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000266 154.0
PYH1_k127_7578140_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000003118 121.0
PYH1_k127_7578140_4 Peptidase C13 family - - - 0.00000003957 65.0
PYH1_k127_7578140_5 helix_turn_helix ASNC type K03719 - - 0.0000003936 62.0
PYH1_k127_7578140_6 ubiE/COQ5 methyltransferase family - - - 0.00001671 57.0
PYH1_k127_7578140_7 Bromodomain adjacent to zinc finger domain K15224 GO:0000183,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0000976,GO:0001013,GO:0001046,GO:0001047,GO:0001067,GO:0001163,GO:0001164,GO:0001188,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005677,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006342,GO:0006351,GO:0006352,GO:0006355,GO:0006356,GO:0006357,GO:0006360,GO:0006361,GO:0006464,GO:0006476,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007275,GO:0007399,GO:0008134,GO:0008150,GO:0008152,GO:0008213,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0016479,GO:0016569,GO:0016570,GO:0016571,GO:0016575,GO:0016604,GO:0016607,GO:0016922,GO:0017053,GO:0018022,GO:0018130,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0022607,GO:0031010,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031497,GO:0031507,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032774,GO:0032991,GO:0033553,GO:0034401,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0034770,GO:0034968,GO:0035257,GO:0035601,GO:0036211,GO:0040029,GO:0042393,GO:0043044,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043565,GO:0043933,GO:0044085,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044728,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051427,GO:0051567,GO:0060255,GO:0061647,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070577,GO:0070603,GO:0070828,GO:0070868,GO:0070869,GO:0070897,GO:0070933,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090568,GO:0097159,GO:0097549,GO:0097659,GO:0098732,GO:0140030,GO:0140033,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1904949,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0006898 50.0
PYH1_k127_7611648_0 ABC transporter, ATP-binding protein K06022,K10834 - 3.6.3.29,3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 302.0
PYH1_k127_7611648_1 - - - - 0.00000000000000000000003465 111.0
PYH1_k127_7611648_2 Aspartyl protease - - - 0.0000000000000002233 85.0
PYH1_k127_7615328_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000001716 60.0
PYH1_k127_7659518_0 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000005086 66.0
PYH1_k127_7659518_1 Erythromycin esterase - - - 0.0000001507 62.0
PYH1_k127_7659899_0 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001016 234.0
PYH1_k127_7659899_1 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000006504 194.0
PYH1_k127_7659899_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000003121 158.0
PYH1_k127_7659899_3 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000008142 123.0
PYH1_k127_7659899_4 COG3227 Zinc metalloprotease (elastase) K08604 - 3.4.24.25 0.00000008603 63.0
PYH1_k127_7659899_5 Copper binding proteins, plastocyanin/azurin family - - - 0.000001165 58.0
PYH1_k127_7672374_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 480.0
PYH1_k127_7672374_1 Cysteinyl-tRNA synthetase K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000004589 226.0
PYH1_k127_7672374_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000000004847 174.0
PYH1_k127_7672374_3 ADP-ribosylglycohydrolase - - - 0.0005002 48.0
PYH1_k127_7678071_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 497.0
PYH1_k127_7678071_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 355.0
PYH1_k127_7678071_2 PFAM amino acid-binding ACT domain protein - - - 0.0000000000002958 74.0
PYH1_k127_7700396_0 PFAM Multicopper oxidase - - - 2.494e-211 676.0
PYH1_k127_7700396_1 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 490.0
PYH1_k127_7700396_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 364.0
PYH1_k127_7700396_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 360.0
PYH1_k127_7700396_4 PFAM Circadian clock protein KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000006168 241.0
PYH1_k127_7700396_5 Pfam:KaiC - - - 0.000000000000000000000000000000000000000002234 165.0
PYH1_k127_7700396_6 DJ-1/PfpI family - - - 0.000000000000000000000000000002809 128.0
PYH1_k127_7700396_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000005278 66.0
PYH1_k127_7700396_8 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0001124 46.0
PYH1_k127_7703722_0 'glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 317.0
PYH1_k127_7703722_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000001102 156.0
PYH1_k127_7703722_2 SPFH domain-Band 7 family - - - 0.0000000000000003783 82.0
PYH1_k127_7716415_0 DnaB-like helicase C terminal domain - - - 0.0000000000000000000002096 106.0
PYH1_k127_7716415_1 regulation of nucleus size - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006996,GO:0006997,GO:0008150,GO:0009987,GO:0016043,GO:0031974,GO:0031981,GO:0032535,GO:0034399,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0065007,GO:0065008,GO:0070013,GO:0071840,GO:0090066,GO:0097298 - 0.00007303 52.0
PYH1_k127_7728070_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 439.0
PYH1_k127_7728070_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000297 267.0
PYH1_k127_7737337_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001709 271.0
PYH1_k127_7737337_1 transcription regulator activity - - - 0.0000000000000000000000000000000000000001153 155.0
PYH1_k127_7737501_0 EamA-like transporter family - - - 0.0000000000000000000000006845 116.0
PYH1_k127_7737501_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000001456 57.0
PYH1_k127_776872_0 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000005219 158.0
PYH1_k127_776872_1 Protein of unknown function (DUF3494) - - - 0.0000000000335 77.0
PYH1_k127_7772025_0 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000001187 119.0
PYH1_k127_7772025_1 DNA-templated transcription, initiation - - - 0.000000001335 70.0
PYH1_k127_7772071_0 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000001278 200.0
PYH1_k127_7772071_1 HAD-hyrolase-like K01560 - 3.8.1.2 0.000000000000000000000001992 112.0
PYH1_k127_7772071_2 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.000000000000008071 86.0
PYH1_k127_7795753_0 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 342.0
PYH1_k127_7795753_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 350.0
PYH1_k127_7795753_2 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000002045 191.0
PYH1_k127_7795753_3 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000006567 147.0
PYH1_k127_7813641_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000004198 177.0
PYH1_k127_7813641_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000002894 60.0
PYH1_k127_7830221_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 379.0
PYH1_k127_7830221_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 335.0
PYH1_k127_7830221_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
PYH1_k127_7830221_3 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000005646 231.0
PYH1_k127_7830221_4 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000481 219.0
PYH1_k127_7830221_5 domain, Protein - - - 0.000000000000000000000000001906 131.0
PYH1_k127_7830221_6 OmpA family - - - 0.0000000000000002852 91.0
PYH1_k127_7830221_7 OmpA family - - - 0.00000000002983 78.0
PYH1_k127_7830221_8 OmpA family K02557,K03286 - - 0.0000000001278 72.0
PYH1_k127_7872780_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001335 239.0
PYH1_k127_7872780_1 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000001228 186.0
PYH1_k127_7881871_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 338.0
PYH1_k127_7888841_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 304.0
PYH1_k127_7888841_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000004137 246.0
PYH1_k127_7891747_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 445.0
PYH1_k127_7891747_1 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 295.0
PYH1_k127_7891747_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000001505 182.0
PYH1_k127_7891747_3 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000007982 164.0
PYH1_k127_7891747_4 Winged helix-turn-helix DNA-binding - - - 0.0000001424 65.0
PYH1_k127_7891747_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000005602 56.0
PYH1_k127_7896896_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 464.0
PYH1_k127_7896896_1 phytoene K15745 - 1.3.99.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 305.0
PYH1_k127_7896896_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000005346 207.0
PYH1_k127_7896896_3 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000002568 59.0
PYH1_k127_7896896_4 Squalene phytoene synthase - - - 0.000003181 60.0
PYH1_k127_7903486_0 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 537.0
PYH1_k127_7903486_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000003704 134.0
PYH1_k127_7903486_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000001733 78.0
PYH1_k127_7918169_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000003386 180.0
PYH1_k127_7918169_1 PFAM PKD domain containing protein - - - 0.00001377 58.0
PYH1_k127_7927888_0 Heat shock 70 kDa protein K04043 - - 3.55e-234 739.0
PYH1_k127_7927888_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000002597 149.0
PYH1_k127_7927888_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000472 104.0
PYH1_k127_7949996_0 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000000000000000000000000000000000001304 184.0
PYH1_k127_7950828_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.599e-231 729.0
PYH1_k127_7950828_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000001718 97.0
PYH1_k127_7950828_2 hydrolase (HAD superfamily) K01560,K07025 - 3.8.1.2 0.0002896 45.0
PYH1_k127_7952481_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 302.0
PYH1_k127_7952481_1 VIT family - - - 0.0000000000000000000000001682 114.0
PYH1_k127_7955934_0 COG1520 FOG WD40-like repeat - - - 0.00000000000001252 87.0
PYH1_k127_7958589_0 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 407.0
PYH1_k127_7958589_1 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 351.0
PYH1_k127_7958589_2 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000005866 183.0
PYH1_k127_7958589_3 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000005876 177.0
PYH1_k127_7958589_4 COG1321 Mn-dependent transcriptional regulator - - - 0.00000000000000000000000000000000005507 139.0
PYH1_k127_7958589_5 Parallel beta-helix repeat K07218 - - 0.00000000000000000003294 108.0
PYH1_k127_7958589_6 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000001759 74.0
PYH1_k127_7958589_7 Protein conserved in bacteria K20276 - - 0.0001092 57.0
PYH1_k127_7962424_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 454.0
PYH1_k127_7962424_1 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000000000000000000007038 189.0
PYH1_k127_7962424_2 Protein of unknown function (DUF835) - - - 0.0000000006852 71.0
PYH1_k127_7963874_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 1.39e-247 790.0
PYH1_k127_799854_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 590.0
PYH1_k127_799854_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 468.0
PYH1_k127_799854_2 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000001322 80.0
PYH1_k127_8028868_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.901e-213 678.0
PYH1_k127_8028868_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000001366 186.0
PYH1_k127_8028868_2 lyase activity - - - 0.000000000000053 85.0
PYH1_k127_8028868_3 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.00003382 55.0
PYH1_k127_805042_0 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000002266 211.0
PYH1_k127_805042_1 cellulase activity K07019 - - 0.00000000000146 81.0
PYH1_k127_8104586_0 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 370.0
PYH1_k127_8104586_1 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.000000000000000000000000000000000000000000003168 172.0
PYH1_k127_8104586_2 - - - - 0.000000000000000000000000003458 115.0
PYH1_k127_8143947_0 PFAM Beta propeller domain K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 430.0
PYH1_k127_8143947_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000002785 138.0
PYH1_k127_81529_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
PYH1_k127_8159633_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 469.0
PYH1_k127_8159633_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 440.0
PYH1_k127_8159633_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000000000000004745 173.0
PYH1_k127_8159633_3 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000005482 151.0
PYH1_k127_8159633_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000003947 87.0
PYH1_k127_8187723_0 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 395.0
PYH1_k127_8187723_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000116 269.0
PYH1_k127_8187723_10 Transcriptional regulator PadR-like family - - - 0.00000000000000003388 90.0
PYH1_k127_8187723_11 cell adhesion involved in biofilm formation K13735,K20276 - - 0.000000000001674 81.0
PYH1_k127_8187723_12 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000002389 73.0
PYH1_k127_8187723_13 aminopeptidase activity K19689 - - 0.0000004558 62.0
PYH1_k127_8187723_14 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00003816 57.0
PYH1_k127_8187723_15 SCP-2 sterol transfer family - - - 0.00004273 55.0
PYH1_k127_8187723_2 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000003956 254.0
PYH1_k127_8187723_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000003233 248.0
PYH1_k127_8187723_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000005279 250.0
PYH1_k127_8187723_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000006384 233.0
PYH1_k127_8187723_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000009007 177.0
PYH1_k127_8187723_7 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000002856 159.0
PYH1_k127_8187723_8 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000006071 151.0
PYH1_k127_8187723_9 Transcriptional regulator K07332 - - 0.00000000000000000000009138 106.0
PYH1_k127_8234019_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 6.765e-231 722.0
PYH1_k127_8234019_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000005439 228.0
PYH1_k127_8234019_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000001889 153.0
PYH1_k127_8240671_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 305.0
PYH1_k127_8240671_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000001676 127.0
PYH1_k127_8240671_2 translation initiation factor activity K06996 - - 0.000000000000007695 81.0
PYH1_k127_8263440_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 545.0
PYH1_k127_8263440_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007298 250.0
PYH1_k127_8263440_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000007619 180.0
PYH1_k127_8263440_3 Rab subfamily of small GTPases K07901 - - 0.0000000000000000000000001904 117.0
PYH1_k127_8263440_4 OmpA family - - - 0.000000000005155 77.0
PYH1_k127_8263440_5 - - - - 0.00000000001629 70.0
PYH1_k127_8266296_0 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000002026 200.0
PYH1_k127_8266296_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000004702 161.0
PYH1_k127_8268269_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 489.0
PYH1_k127_8268269_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 473.0
PYH1_k127_8268269_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002257 194.0
PYH1_k127_8268269_3 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000814 201.0
PYH1_k127_8268269_4 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.00000000000005779 75.0
PYH1_k127_8293949_0 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000001369 216.0
PYH1_k127_8323511_0 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000006225 162.0
PYH1_k127_8340723_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 413.0
PYH1_k127_8340723_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
PYH1_k127_8340723_2 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 312.0
PYH1_k127_8340723_3 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
PYH1_k127_8340723_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
PYH1_k127_8340723_5 DnaB-like helicase C terminal domain K08482 - - 0.00000000000000000000000000000000004861 149.0
PYH1_k127_8340723_6 KaiC - - - 0.00000000000000000000000000000004201 136.0
PYH1_k127_8365373_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 531.0
PYH1_k127_8365373_1 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000005777 236.0
PYH1_k127_8365373_2 PFAM SMC domain protein K03546 - - 0.0000000000001025 85.0
PYH1_k127_8365373_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000001501 78.0
PYH1_k127_8365373_4 NurA - - - 0.00002849 57.0
PYH1_k127_887329_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 368.0