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Overview

ID MAG03129
Name PYH1_bin.16
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus
Species
Assembly information
Completeness (%) 77.47
Contamination (%) 4.4
GC content (%) 51.0
N50 (bp) 5,262
Genome size (bp) 1,631,533

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1717

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1002013_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 374.0
PYH1_k127_1002013_1 - - - - 0.000000000000000000000000000000000000001883 152.0
PYH1_k127_1002013_2 Putative zinc ribbon domain - - - 0.000000000000000003097 91.0
PYH1_k127_1002013_3 - - - - 0.000000000000000003866 88.0
PYH1_k127_1003484_0 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 269.0
PYH1_k127_1003484_1 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000001689 199.0
PYH1_k127_1003484_2 Putative methyltransferase - - - 0.0000000000001833 76.0
PYH1_k127_1020680_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 520.0
PYH1_k127_1020680_1 metal-dependent enzyme K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 295.0
PYH1_k127_1020680_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005099 244.0
PYH1_k127_1020680_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000005284 239.0
PYH1_k127_1020680_4 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000006567 113.0
PYH1_k127_1084972_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.416e-235 745.0
PYH1_k127_1084972_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 295.0
PYH1_k127_1084972_2 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000002743 167.0
PYH1_k127_1084972_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000005318 109.0
PYH1_k127_1084972_4 - - - - 0.000000000000000000000001118 112.0
PYH1_k127_1094110_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 368.0
PYH1_k127_1094110_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 312.0
PYH1_k127_1136770_0 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008024 278.0
PYH1_k127_1136770_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000002287 250.0
PYH1_k127_1136770_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000004037 52.0
PYH1_k127_1154160_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 332.0
PYH1_k127_1161985_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1922.0
PYH1_k127_1161985_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 493.0
PYH1_k127_1161985_2 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 386.0
PYH1_k127_1161985_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002503 260.0
PYH1_k127_1161985_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
PYH1_k127_1161985_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000005723 214.0
PYH1_k127_116261_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 574.0
PYH1_k127_116261_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 491.0
PYH1_k127_116261_2 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 314.0
PYH1_k127_116261_3 - - - - 0.000000000000000000000000000000000000000000000000000000003003 209.0
PYH1_k127_116261_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000003529 177.0
PYH1_k127_116261_5 PFAM metal-dependent phosphohydrolase, HD sub domain K02030 - - 0.000000000000000000000000000000000000007927 162.0
PYH1_k127_1182030_1 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003536 254.0
PYH1_k127_1182030_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000116 206.0
PYH1_k127_1182030_3 permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000001729 138.0
PYH1_k127_1196306_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000005564 199.0
PYH1_k127_1196306_1 - - - - 0.000000000000000000000000000000000000000006781 175.0
PYH1_k127_1199_0 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 405.0
PYH1_k127_1199_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
PYH1_k127_1199_2 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001872 268.0
PYH1_k127_1199_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000001855 95.0
PYH1_k127_1199_4 COG0784 FOG CheY-like receiver K11443 - - 0.000000000000000000003901 99.0
PYH1_k127_1206113_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1020.0
PYH1_k127_1206113_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 6.454e-250 795.0
PYH1_k127_1206113_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 509.0
PYH1_k127_1206113_3 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 363.0
PYH1_k127_1206113_4 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 303.0
PYH1_k127_1206113_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000001116 209.0
PYH1_k127_1206113_6 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000001726 137.0
PYH1_k127_1206113_7 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000004016 129.0
PYH1_k127_1229548_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 591.0
PYH1_k127_1229548_1 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
PYH1_k127_1229548_2 HD domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
PYH1_k127_1229548_3 viral genome integration into host DNA K04763 - - 0.000000000000000000000000000000000000000005089 155.0
PYH1_k127_1229548_4 PFAM PHP domain - - - 0.000000000000000000000000000000000000000008148 161.0
PYH1_k127_1229548_5 AIR carboxylase K06898 - - 0.000000000000000000000000000001413 121.0
PYH1_k127_1229548_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000002296 113.0
PYH1_k127_1229548_7 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0004649 49.0
PYH1_k127_1263057_0 Peptidase family M48 - - - 0.00000000000477 75.0
PYH1_k127_1290713_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 469.0
PYH1_k127_1290713_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.00000000000000000000000000001359 123.0
PYH1_k127_1290713_2 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000006091 119.0
PYH1_k127_1290713_3 - - - - 0.0000000000002258 71.0
PYH1_k127_1315226_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 499.0
PYH1_k127_1315226_1 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 451.0
PYH1_k127_1315226_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000001431 196.0
PYH1_k127_1315226_3 HNH nucleases - - - 0.00000000000000000000000000000000000000001638 155.0
PYH1_k127_1319213_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1533.0
PYH1_k127_1319213_1 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 543.0
PYH1_k127_1319213_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 462.0
PYH1_k127_1319213_3 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 397.0
PYH1_k127_1319213_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 396.0
PYH1_k127_1319213_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000003827 179.0
PYH1_k127_1337779_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 350.0
PYH1_k127_1337779_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 257.0
PYH1_k127_1337779_2 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000001335 168.0
PYH1_k127_1385843_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 437.0
PYH1_k127_1385843_1 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 424.0
PYH1_k127_1385843_10 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000001503 83.0
PYH1_k127_1385843_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 395.0
PYH1_k127_1385843_3 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000001665 244.0
PYH1_k127_1385843_4 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
PYH1_k127_1385843_5 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000003505 185.0
PYH1_k127_1385843_6 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000004606 177.0
PYH1_k127_1385843_7 PFAM aminoglycoside phosphotransferase K18817 - 2.7.1.163 0.0000000000000000000000000000000003745 144.0
PYH1_k127_1385843_8 PFAM CBS domain - - - 0.000000000000000000000000000000003687 135.0
PYH1_k127_1385843_9 Cobalt transport protein K02008 - - 0.00000000000000000000000000007709 128.0
PYH1_k127_142596_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 472.0
PYH1_k127_142596_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 373.0
PYH1_k127_143234_0 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002604 282.0
PYH1_k127_143234_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000002157 164.0
PYH1_k127_143234_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000009619 95.0
PYH1_k127_143234_3 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000189 50.0
PYH1_k127_1436777_0 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 439.0
PYH1_k127_1436777_1 GAF domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001208 257.0
PYH1_k127_1436777_2 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000000000007357 185.0
PYH1_k127_1436777_3 - K07092 - - 0.00006766 51.0
PYH1_k127_1451220_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 373.0
PYH1_k127_1451220_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000382 274.0
PYH1_k127_1465516_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1132.0
PYH1_k127_1465516_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
PYH1_k127_1471329_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 421.0
PYH1_k127_1471329_1 galactose-1-phosphate K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 336.0
PYH1_k127_1471329_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 326.0
PYH1_k127_1471329_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
PYH1_k127_1471329_4 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000003287 209.0
PYH1_k127_1471329_5 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000524 135.0
PYH1_k127_1471329_6 cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000007866 109.0
PYH1_k127_1533812_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 484.0
PYH1_k127_1533812_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000005726 162.0
PYH1_k127_1549183_0 Aminotransferase class-III K01845 - 5.4.3.8 1.23e-207 652.0
PYH1_k127_1549183_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 488.0
PYH1_k127_1549183_10 YGGT family K02221 - - 0.000000000000000000000000000000000007241 138.0
PYH1_k127_1549183_11 Transcriptional regulator - - - 0.000000000000000000000000000000000007733 143.0
PYH1_k127_1549183_12 radical SAM domain protein - - - 0.000000000000000000000000000000006647 131.0
PYH1_k127_1549183_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000005455 130.0
PYH1_k127_1549183_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 446.0
PYH1_k127_1549183_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
PYH1_k127_1549183_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005882 246.0
PYH1_k127_1549183_5 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000002256 226.0
PYH1_k127_1549183_6 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000002411 222.0
PYH1_k127_1549183_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000003394 207.0
PYH1_k127_1549183_8 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000853 185.0
PYH1_k127_1549183_9 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000008636 152.0
PYH1_k127_155292_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 396.0
PYH1_k127_155292_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000001198 196.0
PYH1_k127_155292_2 HD domain - - - 0.000000008682 65.0
PYH1_k127_1560481_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1082.0
PYH1_k127_1560481_1 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000002297 83.0
PYH1_k127_1560481_2 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000002914 80.0
PYH1_k127_1560481_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.197 0.000000000000006501 84.0
PYH1_k127_1561858_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1112.0
PYH1_k127_1561858_1 4Fe-4S ferredoxin K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 263.0
PYH1_k127_1561858_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000001369 209.0
PYH1_k127_1561858_3 Protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000588 134.0
PYH1_k127_1561858_4 COG3547 Transposase and inactivated derivatives - - - 0.000000000000000000000000000007239 124.0
PYH1_k127_1579436_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 6.359e-251 787.0
PYH1_k127_1579436_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
PYH1_k127_1579436_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 271.0
PYH1_k127_1579436_3 CBS domain - - - 0.0000000000000000000001657 102.0
PYH1_k127_1579436_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000007278 96.0
PYH1_k127_1607925_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 391.0
PYH1_k127_1607925_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
PYH1_k127_1607925_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000005861 210.0
PYH1_k127_1607925_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.0000000000000000000000000000000003592 136.0
PYH1_k127_1607925_4 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000006686 133.0
PYH1_k127_1607925_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000004547 137.0
PYH1_k127_1607925_6 - - - - 0.000000000000000005182 94.0
PYH1_k127_1645960_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.928e-209 655.0
PYH1_k127_1645960_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 404.0
PYH1_k127_1645960_2 PFAM DNA alkylation repair enzyme - - - 0.00000000001081 65.0
PYH1_k127_1645960_3 Male sterility protein K00091 - 1.1.1.219 0.00000000005688 68.0
PYH1_k127_1686669_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 610.0
PYH1_k127_1686669_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 566.0
PYH1_k127_1686669_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 434.0
PYH1_k127_1686669_3 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 355.0
PYH1_k127_1686669_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 289.0
PYH1_k127_1686669_5 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000007371 221.0
PYH1_k127_1686669_6 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000347 212.0
PYH1_k127_1686669_7 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000002828 194.0
PYH1_k127_1686669_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000001814 92.0
PYH1_k127_1710381_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.739e-213 667.0
PYH1_k127_1710381_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.24e-205 642.0
PYH1_k127_1710381_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000002436 182.0
PYH1_k127_1710381_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000003064 88.0
PYH1_k127_1710381_4 component of anaerobic dehydrogenases - - - 0.0000001048 61.0
PYH1_k127_1731298_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1176.0
PYH1_k127_1731298_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 377.0
PYH1_k127_1731298_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002574 235.0
PYH1_k127_1731298_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000001807 156.0
PYH1_k127_1731298_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000006318 90.0
PYH1_k127_1731298_5 LysM domain - - - 0.0000000000000001005 93.0
PYH1_k127_1738826_0 FAD binding domain K00278 - 1.4.3.16 2.542e-206 655.0
PYH1_k127_1738826_1 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - - - 0.00000000000000000000000003724 111.0
PYH1_k127_1752935_0 TonB-dependent Receptor Plug Domain K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 547.0
PYH1_k127_1752935_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 519.0
PYH1_k127_1752935_10 PFAM response regulator receiver K02481,K07712 - - 0.000000000000000002558 93.0
PYH1_k127_1752935_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000001227 59.0
PYH1_k127_1752935_12 - - - - 0.0004082 44.0
PYH1_k127_1752935_2 cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 465.0
PYH1_k127_1752935_3 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000573 225.0
PYH1_k127_1752935_4 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000005863 206.0
PYH1_k127_1752935_5 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000001155 203.0
PYH1_k127_1752935_6 protein methyltransferase activity K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000009322 176.0
PYH1_k127_1752935_7 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000004035 93.0
PYH1_k127_1752935_8 - - - - 0.00000000000000000001628 92.0
PYH1_k127_1752935_9 PFAM plasmid stabilization system K06218 - - 0.000000000000000001286 86.0
PYH1_k127_1760627_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.256e-311 968.0
PYH1_k127_1760627_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000452 228.0
PYH1_k127_1760627_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000007849 124.0
PYH1_k127_1798306_0 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000636 274.0
PYH1_k127_1798306_1 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005619 267.0
PYH1_k127_1798306_2 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000379 209.0
PYH1_k127_1798306_3 TupA-like ATPgrasp - - - 0.0000000000000000000000000000001947 127.0
PYH1_k127_1798306_4 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000005329 112.0
PYH1_k127_1798306_5 - - - - 0.0000000000000000000004462 110.0
PYH1_k127_1798314_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1124.0
PYH1_k127_1798314_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007825 250.0
PYH1_k127_1798314_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001083 218.0
PYH1_k127_1798314_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000005736 181.0
PYH1_k127_1798314_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000001821 174.0
PYH1_k127_1801062_0 sister chromatid segregation - - - 3.941e-207 654.0
PYH1_k127_1801062_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
PYH1_k127_1910565_0 membrane transporter protein K07090 - - 1.592e-196 619.0
PYH1_k127_1910565_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 405.0
PYH1_k127_1910565_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 312.0
PYH1_k127_1910565_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003795 259.0
PYH1_k127_1910565_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001874 231.0
PYH1_k127_1910565_5 AMP binding - - - 0.0000000000000000000000000000000000000001278 155.0
PYH1_k127_1927512_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 327.0
PYH1_k127_1927512_1 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008238 245.0
PYH1_k127_1972138_0 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000001292 149.0
PYH1_k127_1972138_1 fimbrial assembly K02461 - - 0.000000005958 68.0
PYH1_k127_1972138_2 Pfam:N_methyl_2 K02459 - - 0.000002579 57.0
PYH1_k127_1973413_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 598.0
PYH1_k127_1973413_1 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 566.0
PYH1_k127_1973413_2 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000009324 97.0
PYH1_k127_1973413_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000952 102.0
PYH1_k127_1980743_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000005742 216.0
PYH1_k127_1980743_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000002986 202.0
PYH1_k127_1980743_2 PSP1 domain protein - - - 0.000005509 50.0
PYH1_k127_1992957_0 Flavodoxin - - - 2.268e-205 644.0
PYH1_k127_1992957_1 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000001072 174.0
PYH1_k127_1992957_2 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000002221 184.0
PYH1_k127_1992957_3 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000008033 55.0
PYH1_k127_1992957_4 PFAM DsrE K07235 - - 0.0000002927 57.0
PYH1_k127_1992957_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000009296 57.0
PYH1_k127_1992957_6 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.00001025 51.0
PYH1_k127_1992957_7 DsrE/DsrF-like family K07236 - - 0.0003573 48.0
PYH1_k127_2009388_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 2.014e-228 723.0
PYH1_k127_2009388_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 586.0
PYH1_k127_2009388_2 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 370.0
PYH1_k127_2009388_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 340.0
PYH1_k127_2009388_4 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000006122 126.0
PYH1_k127_2009388_5 4Fe-4S binding domain - - - 0.0000000000000000001078 91.0
PYH1_k127_2009388_6 Sulfurtransferase TusA K04085 - - 0.000000000000001822 79.0
PYH1_k127_2009388_7 Belongs to the peptidase M16 family K07263 - - 0.0000001733 57.0
PYH1_k127_2009388_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0005617 48.0
PYH1_k127_2011797_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 531.0
PYH1_k127_2011797_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000003114 267.0
PYH1_k127_2011797_2 Phosphoribosyl transferase domain - - - 0.00000001143 59.0
PYH1_k127_2011797_3 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0001227 51.0
PYH1_k127_2014181_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 561.0
PYH1_k127_2014181_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 457.0
PYH1_k127_2014181_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 337.0
PYH1_k127_2014181_3 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000001196 130.0
PYH1_k127_2014181_4 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000001424 77.0
PYH1_k127_2024057_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 430.0
PYH1_k127_2024057_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000002375 128.0
PYH1_k127_202840_0 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
PYH1_k127_202840_1 ABC 3 transport family K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000002289 222.0
PYH1_k127_202840_2 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000002366 223.0
PYH1_k127_2035576_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 366.0
PYH1_k127_2035576_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
PYH1_k127_2035576_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000004601 264.0
PYH1_k127_2035576_3 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000209 106.0
PYH1_k127_2035576_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000006047 90.0
PYH1_k127_2035576_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000004784 82.0
PYH1_k127_2035641_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 390.0
PYH1_k127_2035641_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 377.0
PYH1_k127_2035641_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 339.0
PYH1_k127_2035641_3 ferrous iron binding K06990,K09141 - - 0.0000000000000000536 81.0
PYH1_k127_2035641_4 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000000000000916 83.0
PYH1_k127_2036658_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.301e-202 642.0
PYH1_k127_2036658_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000007342 112.0
PYH1_k127_2058653_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 326.0
PYH1_k127_2058653_1 PINc domain ribonuclease K09006 - - 0.00000000000000000000000000000000000000000000000000000000000000008957 229.0
PYH1_k127_2058653_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000004643 124.0
PYH1_k127_2058653_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00001866 48.0
PYH1_k127_2069502_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.061e-305 942.0
PYH1_k127_2069502_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 493.0
PYH1_k127_2069502_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 342.0
PYH1_k127_2069502_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000004091 254.0
PYH1_k127_2069502_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000006618 214.0
PYH1_k127_2069502_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000001122 214.0
PYH1_k127_2147735_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.435e-204 642.0
PYH1_k127_2147735_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 475.0
PYH1_k127_2147735_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
PYH1_k127_2147735_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000002834 207.0
PYH1_k127_2147735_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000002166 103.0
PYH1_k127_2147735_5 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00007549 48.0
PYH1_k127_2147937_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 3.33e-227 710.0
PYH1_k127_2147937_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 581.0
PYH1_k127_2147937_10 Predicted RNA-binding protein - - - 0.00000000000000003238 84.0
PYH1_k127_2147937_11 PFAM Fimbrial assembly K02461 - - 0.0000000008365 66.0
PYH1_k127_2147937_12 Type II secretion system (T2SS), protein M subtype b - - - 0.000000003048 65.0
PYH1_k127_2147937_13 beta-lactamase domain protein - - - 0.0008741 42.0
PYH1_k127_2147937_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 528.0
PYH1_k127_2147937_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 511.0
PYH1_k127_2147937_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 356.0
PYH1_k127_2147937_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 281.0
PYH1_k127_2147937_6 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000923 250.0
PYH1_k127_2147937_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000006257 240.0
PYH1_k127_2147937_8 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000000000009483 189.0
PYH1_k127_2147937_9 MazG-like family - - - 0.00000000000000000000000000000005686 130.0
PYH1_k127_215675_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
PYH1_k127_215675_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000002778 205.0
PYH1_k127_215675_2 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000001783 209.0
PYH1_k127_215675_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000001251 157.0
PYH1_k127_2161155_0 Belongs to the CarB family K01955 - 6.3.5.5 2.035e-259 809.0
PYH1_k127_2161155_1 6-phosphofructokinase activity K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 324.0
PYH1_k127_2162661_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 594.0
PYH1_k127_2162661_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 488.0
PYH1_k127_2162661_2 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000009072 194.0
PYH1_k127_2163377_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.667e-264 834.0
PYH1_k127_2164711_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 301.0
PYH1_k127_2164711_1 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004786 282.0
PYH1_k127_2164711_2 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001125 278.0
PYH1_k127_2164711_3 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
PYH1_k127_2164711_4 PFAM Nitrate reductase gamma subunit - - - 0.000000000000001443 85.0
PYH1_k127_2164711_5 - - - - 0.00000000000001136 79.0
PYH1_k127_2198881_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1105.0
PYH1_k127_2198881_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 412.0
PYH1_k127_2198881_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 325.0
PYH1_k127_2198881_3 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000006038 175.0
PYH1_k127_2198881_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000002521 140.0
PYH1_k127_2319905_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 535.0
PYH1_k127_2319905_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000217 209.0
PYH1_k127_2319905_2 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000000001129 185.0
PYH1_k127_2319905_3 transposase activity K07483,K07497 - - 0.000000000000000000000000000000000000000000002869 169.0
PYH1_k127_2324815_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 437.0
PYH1_k127_2324815_1 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 388.0
PYH1_k127_2324815_10 Predicted permease YjgP/YjgQ family K11720 - - 0.000002599 50.0
PYH1_k127_2324815_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 396.0
PYH1_k127_2324815_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 319.0
PYH1_k127_2324815_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000887 281.0
PYH1_k127_2324815_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002603 281.0
PYH1_k127_2324815_6 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000007736 214.0
PYH1_k127_2324815_7 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000006948 161.0
PYH1_k127_2324815_8 YqeY-like protein K09117 - - 0.00000000000000000000000000000000001712 140.0
PYH1_k127_2324815_9 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000009182 89.0
PYH1_k127_2334692_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
PYH1_k127_2334692_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 319.0
PYH1_k127_2334692_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000965 86.0
PYH1_k127_234737_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 552.0
PYH1_k127_234737_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 346.0
PYH1_k127_234737_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000001896 177.0
PYH1_k127_234737_3 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000156 60.0
PYH1_k127_2405032_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.575e-318 992.0
PYH1_k127_2405032_1 LysM domain K08307,K12204,K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
PYH1_k127_2405032_2 - - - - 0.0000000000000000000000000000000000000006377 151.0
PYH1_k127_2405032_4 HEAT repeat - - - 0.000001669 58.0
PYH1_k127_2428943_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 361.0
PYH1_k127_2428943_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000009715 208.0
PYH1_k127_2428943_2 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000427 106.0
PYH1_k127_2428943_3 PFAM translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000005573 94.0
PYH1_k127_245032_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.053e-224 703.0
PYH1_k127_245032_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 425.0
PYH1_k127_245032_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 371.0
PYH1_k127_245032_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000005404 195.0
PYH1_k127_245032_4 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000001414 176.0
PYH1_k127_245032_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000001609 166.0
PYH1_k127_2516725_0 COG0058 Glucan phosphorylase - - - 2.525e-255 798.0
PYH1_k127_2516725_1 Histidine kinase - - - 1.889e-205 675.0
PYH1_k127_2516725_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002037 286.0
PYH1_k127_2516725_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005109 277.0
PYH1_k127_2516725_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000002358 145.0
PYH1_k127_2516725_5 - - - - 0.0000000000000000000000007537 104.0
PYH1_k127_2516725_6 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000002488 74.0
PYH1_k127_251677_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.532e-229 717.0
PYH1_k127_251677_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 534.0
PYH1_k127_251677_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 327.0
PYH1_k127_251677_3 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
PYH1_k127_251677_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000001263 208.0
PYH1_k127_251677_5 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000000000003984 174.0
PYH1_k127_251677_6 cell division ATP-binding protein FtsE K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.00000000000000000000000000000002458 128.0
PYH1_k127_2517975_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.567e-294 915.0
PYH1_k127_2517975_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 292.0
PYH1_k127_2517975_2 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000168 258.0
PYH1_k127_2517975_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000506 183.0
PYH1_k127_2518585_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 405.0
PYH1_k127_2518585_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 325.0
PYH1_k127_255360_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 394.0
PYH1_k127_255360_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 331.0
PYH1_k127_255360_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000009934 138.0
PYH1_k127_255360_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000002141 115.0
PYH1_k127_255360_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000008232 111.0
PYH1_k127_255360_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007041 104.0
PYH1_k127_255360_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000008041 102.0
PYH1_k127_255360_15 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000003153 93.0
PYH1_k127_255360_16 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000006979 68.0
PYH1_k127_255360_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002775 267.0
PYH1_k127_255360_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
PYH1_k127_255360_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
PYH1_k127_255360_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008944 199.0
PYH1_k127_255360_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000005904 163.0
PYH1_k127_255360_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000002022 156.0
PYH1_k127_255360_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000001265 156.0
PYH1_k127_255360_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000001505 144.0
PYH1_k127_255616_0 Beta-lactamase - - - 8.886e-260 824.0
PYH1_k127_255616_1 MOSC domain - - - 0.0000000000000000000000000000000003457 133.0
PYH1_k127_255616_2 Putative glycosyl hydrolase domain - - - 0.000000000004374 66.0
PYH1_k127_2564762_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 346.0
PYH1_k127_2564762_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 320.0
PYH1_k127_2564762_2 YtxH-like protein - - - 0.00000000000000000000000000000004382 129.0
PYH1_k127_2564762_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000006306 82.0
PYH1_k127_2567834_0 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002767 268.0
PYH1_k127_2567834_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000004738 208.0
PYH1_k127_2567834_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000002016 190.0
PYH1_k127_2579350_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 616.0
PYH1_k127_2579350_1 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 518.0
PYH1_k127_2579350_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000004052 115.0
PYH1_k127_2581581_0 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 398.0
PYH1_k127_2581581_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 347.0
PYH1_k127_2581581_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 299.0
PYH1_k127_2581581_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000006482 150.0
PYH1_k127_2581581_4 - - - - 0.000000000000000000001998 97.0
PYH1_k127_2586429_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.577e-244 763.0
PYH1_k127_2586429_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.081e-234 731.0
PYH1_k127_2586429_2 isoprenoid biosynthetic process K00795,K02523,K13789 GO:0003674,GO:0003824,GO:0004161,GO:0004311,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000005297 158.0
PYH1_k127_2586429_3 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000002814 144.0
PYH1_k127_2600442_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000001787 248.0
PYH1_k127_2600442_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000008327 107.0
PYH1_k127_2650623_0 Domain of unknown function (DUF4070) - - - 5.495e-206 651.0
PYH1_k127_2650623_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 474.0
PYH1_k127_2650623_2 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
PYH1_k127_2650623_3 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000004417 190.0
PYH1_k127_2650623_4 Predicted membrane protein (DUF2127) - - - 0.0000000000000000000000000000000000000000000000000108 184.0
PYH1_k127_2650623_5 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.00000000000000000000001439 100.0
PYH1_k127_2663983_0 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000005636 232.0
PYH1_k127_2663983_1 - - - - 0.00000000000000000000000000000000001788 139.0
PYH1_k127_2663983_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000001151 123.0
PYH1_k127_2663983_3 Psort location CytoplasmicMembrane, score 9.46 - - - 0.000000000000000000000001083 105.0
PYH1_k127_266436_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 325.0
PYH1_k127_2687280_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 321.0
PYH1_k127_2687280_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001669 273.0
PYH1_k127_2687280_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000007819 102.0
PYH1_k127_2687280_3 PFAM Mammalian cell entry related K02067 - - 0.0000000000000000000001095 109.0
PYH1_k127_2687280_4 STAS domain K04749 - - 0.000000000000000000002146 97.0
PYH1_k127_2687280_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000211 76.0
PYH1_k127_2700863_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
PYH1_k127_2700863_2 Permease, YjgP YjgQ family K11720 - - 0.00001102 52.0
PYH1_k127_2701107_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.071e-285 893.0
PYH1_k127_2701107_1 response regulator - - - 0.0000000000000000000000000000000301 138.0
PYH1_k127_2771037_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006613 263.0
PYH1_k127_2771037_1 PFAM CheW domain protein K03408 - - 0.000000000000000000004125 100.0
PYH1_k127_2771037_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000005303 58.0
PYH1_k127_2771037_3 chemotaxis protein K03406 - - 0.00000003471 66.0
PYH1_k127_277291_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 418.0
PYH1_k127_2813795_0 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000004884 90.0
PYH1_k127_2923011_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 370.0
PYH1_k127_2923011_1 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001371 250.0
PYH1_k127_2923011_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006871 241.0
PYH1_k127_2923011_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000001784 173.0
PYH1_k127_2923011_4 Tetratricopeptide repeat - - - 0.000000000004691 75.0
PYH1_k127_2923011_5 - - - - 0.000000002519 67.0
PYH1_k127_2923011_6 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.0007951 50.0
PYH1_k127_2938139_0 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 460.0
PYH1_k127_2938139_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000006465 124.0
PYH1_k127_2938139_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000003081 114.0
PYH1_k127_2938139_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000007473 112.0
PYH1_k127_3041847_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.473e-313 983.0
PYH1_k127_3041847_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 379.0
PYH1_k127_3041847_2 - - - - 0.000000000000000000000000000000000000000000000000000000008476 205.0
PYH1_k127_3042888_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 489.0
PYH1_k127_3042888_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001195 273.0
PYH1_k127_3042888_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000003065 100.0
PYH1_k127_3053940_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 4.047e-226 713.0
PYH1_k127_3053940_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
PYH1_k127_3053940_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 387.0
PYH1_k127_3053940_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000002493 224.0
PYH1_k127_3053940_4 Threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000002203 173.0
PYH1_k127_3053940_5 - - - - 0.000005548 51.0
PYH1_k127_3076112_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 347.0
PYH1_k127_3076112_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000785 265.0
PYH1_k127_3076112_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000003214 61.0
PYH1_k127_3093704_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 490.0
PYH1_k127_3093704_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000001335 111.0
PYH1_k127_3093704_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000001504 97.0
PYH1_k127_3093704_3 toxin-antitoxin pair type II binding - - - 0.0000000001055 65.0
PYH1_k127_3102720_0 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 370.0
PYH1_k127_3102720_1 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
PYH1_k127_3102720_2 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
PYH1_k127_3102720_3 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000004192 190.0
PYH1_k127_3102720_4 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000005939 112.0
PYH1_k127_3156799_0 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 1.979e-198 629.0
PYH1_k127_3156799_1 Phosphoglycerate kinase K00927 - 2.7.2.3 1.127e-194 615.0
PYH1_k127_3156799_2 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000002624 128.0
PYH1_k127_3156799_3 response regulator - - - 0.0000000000000000002669 90.0
PYH1_k127_3156799_4 part of a sulfur-relay system K11179 - - 0.00000000000000003095 84.0
PYH1_k127_3165034_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 572.0
PYH1_k127_3165034_1 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 468.0
PYH1_k127_3165034_2 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000002759 274.0
PYH1_k127_3185834_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.609e-310 969.0
PYH1_k127_3185834_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 379.0
PYH1_k127_3185834_2 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.000000000000000000000000000000000000000000000000000000002137 206.0
PYH1_k127_3185834_3 SMART Cold shock protein K03704 - - 0.00000000000000000000000000002693 119.0
PYH1_k127_3185834_4 - - - - 0.000000006541 62.0
PYH1_k127_3225148_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.017e-194 612.0
PYH1_k127_3225148_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
PYH1_k127_3225148_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000002246 192.0
PYH1_k127_3225148_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000006239 99.0
PYH1_k127_3323112_0 anaerobic electron transport chain - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 344.0
PYH1_k127_3323112_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
PYH1_k127_3323112_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001182 241.0
PYH1_k127_3337222_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 582.0
PYH1_k127_3337222_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000192 106.0
PYH1_k127_3337222_2 Bacterial periplasmic substrate-binding proteins - - - 0.0000009973 51.0
PYH1_k127_3337222_3 ATP-independent chaperone mediated protein folding - - - 0.000002284 57.0
PYH1_k127_3337222_4 ubiE/COQ5 methyltransferase family - - - 0.0002521 51.0
PYH1_k127_3350724_0 Trypsin-like peptidase domain - - - 0.000000000000000000000001155 115.0
PYH1_k127_3350724_1 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000000003049 105.0
PYH1_k127_3350724_2 deoxyhypusine monooxygenase activity - - - 0.000000000000000000005454 103.0
PYH1_k127_3355490_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 331.0
PYH1_k127_3355490_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000007222 148.0
PYH1_k127_3355490_2 Universal stress protein family - - - 0.00000000000000000000000000000000000023 145.0
PYH1_k127_3355490_3 proteolysis K03665 - - 0.00000000000000000000000000001801 123.0
PYH1_k127_3373979_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.25e-275 861.0
PYH1_k127_3373979_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.09e-247 775.0
PYH1_k127_3373979_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000001539 92.0
PYH1_k127_3373979_11 TIGRFAM caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000006527 69.0
PYH1_k127_3373979_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 323.0
PYH1_k127_3373979_3 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000004371 248.0
PYH1_k127_3373979_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000002133 241.0
PYH1_k127_3373979_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000007382 197.0
PYH1_k127_3373979_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000002862 151.0
PYH1_k127_3373979_7 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000005383 114.0
PYH1_k127_3373979_8 phosphohydrolase - - - 0.0000000000000000000005096 107.0
PYH1_k127_3373979_9 cheY-homologous receiver domain - - - 0.00000000000000000005346 95.0
PYH1_k127_3394156_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 597.0
PYH1_k127_3394156_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
PYH1_k127_3395079_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.974e-225 710.0
PYH1_k127_3395079_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 475.0
PYH1_k127_3395079_2 ISXO2-like transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
PYH1_k127_3395079_3 FecR protein - - - 0.0000000000000000000000000000000000003793 148.0
PYH1_k127_3395079_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000001421 115.0
PYH1_k127_3395079_5 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000001137 65.0
PYH1_k127_3417927_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 556.0
PYH1_k127_3417927_1 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
PYH1_k127_3417927_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000207 130.0
PYH1_k127_3417927_3 Domain of unknown function (DUF4390) - - - 0.00001217 55.0
PYH1_k127_3417927_4 ADP-glyceromanno-heptose 6-epimerase activity K00754,K08678,K13613 - 4.1.1.35 0.00001516 49.0
PYH1_k127_3418901_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 558.0
PYH1_k127_3418901_1 - K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 391.0
PYH1_k127_3418901_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 307.0
PYH1_k127_3418901_3 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 289.0
PYH1_k127_3418901_4 Diguanylate cyclase K21084 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000006268 287.0
PYH1_k127_3418901_5 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000003863 243.0
PYH1_k127_3418901_6 Methyltransferase MtaA K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000007175 205.0
PYH1_k127_3418901_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000003198 145.0
PYH1_k127_3418901_8 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000002571 138.0
PYH1_k127_3418901_9 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000007633 81.0
PYH1_k127_3426951_0 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000000000001523 190.0
PYH1_k127_3426951_1 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000000000002525 180.0
PYH1_k127_3426951_2 denitrification pathway - - - 0.0000000000000000000000000000000000000008242 160.0
PYH1_k127_3426951_3 12 heme-binding sites - - - 0.000000000000000000000000000000000000005977 156.0
PYH1_k127_3435847_0 Belongs to the protease inhibitor I11 (ecotin) family K08276 - - 0.00000000000000000000000000000000000000000000000000000000000000000002488 235.0
PYH1_k127_3435847_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000002837 196.0
PYH1_k127_3435847_2 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.000000000000000000000000000000000000000000000006563 182.0
PYH1_k127_3452155_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1147.0
PYH1_k127_3455009_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007225 267.0
PYH1_k127_3455009_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001769 247.0
PYH1_k127_3455009_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
PYH1_k127_3455009_3 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
PYH1_k127_3455009_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000003653 203.0
PYH1_k127_3455009_5 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000008352 154.0
PYH1_k127_3455009_6 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000003309 141.0
PYH1_k127_3455009_7 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000001113 123.0
PYH1_k127_3455009_8 energy transducer activity K03646,K03832 - - 0.00000000000000000009109 98.0
PYH1_k127_3455009_9 Outer membrane lipoprotein - - - 0.000004603 53.0
PYH1_k127_3472471_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007148 265.0
PYH1_k127_3472471_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000001889 149.0
PYH1_k127_3472471_2 - - - - 0.000000000001173 72.0
PYH1_k127_3472471_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000002662 68.0
PYH1_k127_3472471_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000002398 64.0
PYH1_k127_3482048_0 chelatase, subunit ChlI K07391 - - 0.000000000000000000000000000000000000000000000000000001885 194.0
PYH1_k127_3482048_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000001418 189.0
PYH1_k127_3482048_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000007632 116.0
PYH1_k127_3482472_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 464.0
PYH1_k127_3482472_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 454.0
PYH1_k127_3482472_2 lysyltransferase activity K07027 - - 0.0000000000000000000107 97.0
PYH1_k127_3492973_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.156e-267 830.0
PYH1_k127_3492973_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 2.738e-254 800.0
PYH1_k127_3492973_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 357.0
PYH1_k127_3492973_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
PYH1_k127_3492973_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000002609 189.0
PYH1_k127_3492973_5 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000002443 188.0
PYH1_k127_3496123_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000006867 194.0
PYH1_k127_3496123_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000006972 121.0
PYH1_k127_3496123_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000003097 120.0
PYH1_k127_3501099_0 Fructose-bisphosphate aldolase class-II - - - 7.464e-197 623.0
PYH1_k127_3501099_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 614.0
PYH1_k127_3501099_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 569.0
PYH1_k127_3501099_3 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 341.0
PYH1_k127_3501099_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 297.0
PYH1_k127_3501099_5 - - - - 0.000000000000000000000000000000000000000000000000000002241 202.0
PYH1_k127_3501099_6 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000003882 188.0
PYH1_k127_3501099_7 - - - - 0.000000004699 59.0
PYH1_k127_3501099_8 DNA polymerase X family K02347 - - 0.000002439 51.0
PYH1_k127_3511023_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 560.0
PYH1_k127_3511023_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 468.0
PYH1_k127_3511023_10 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000002011 75.0
PYH1_k127_3511023_2 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 379.0
PYH1_k127_3511023_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 332.0
PYH1_k127_3511023_4 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 301.0
PYH1_k127_3511023_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006555 267.0
PYH1_k127_3511023_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000001046 190.0
PYH1_k127_3511023_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000003853 170.0
PYH1_k127_3511023_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000001257 148.0
PYH1_k127_3511023_9 - K07112 - - 0.000000000000000000000000000000000003666 143.0
PYH1_k127_3517083_0 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 264.0
PYH1_k127_3517083_1 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000004522 171.0
PYH1_k127_3517083_2 Protein of unknown function (DUF2905) - - - 0.00000000000000000000818 94.0
PYH1_k127_352279_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 541.0
PYH1_k127_352279_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000002695 228.0
PYH1_k127_352279_2 MlaC protein K07323 - - 0.000000000000000000000000000000000000001857 149.0
PYH1_k127_352279_3 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000002002 74.0
PYH1_k127_3572020_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 6.016e-201 637.0
PYH1_k127_3572020_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 314.0
PYH1_k127_3572020_2 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000001149 231.0
PYH1_k127_3572020_3 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000001239 128.0
PYH1_k127_3572020_4 - - - - 0.0000000000000000003182 99.0
PYH1_k127_3572020_5 Glycosyl transferases group 1 - - - 0.000000000000008867 78.0
PYH1_k127_3572020_6 - - - - 0.0000001273 55.0
PYH1_k127_3579881_0 PFAM transposase mutator type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 547.0
PYH1_k127_3579881_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000009424 232.0
PYH1_k127_3579881_2 PFAM nuclease (SNase domain protein) - - - 0.000000000000000003832 87.0
PYH1_k127_3579881_3 Staphylococcal nuclease homologues - - - 0.000000002666 59.0
PYH1_k127_3613137_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 464.0
PYH1_k127_3613137_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001931 294.0
PYH1_k127_3613137_2 Glycosyltransferase like family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007288 273.0
PYH1_k127_3613137_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000174 266.0
PYH1_k127_3613137_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000001004 222.0
PYH1_k127_3613137_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000004053 110.0
PYH1_k127_3613137_6 CoA-binding domain K00996 - 2.7.8.6 0.00000000000000001695 89.0
PYH1_k127_3614730_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000002668 189.0
PYH1_k127_3614730_1 pfam abc K09691 - - 0.000000000000000006907 86.0
PYH1_k127_3614730_2 Iron-sulfur cluster-binding domain - - - 0.0000000000001058 75.0
PYH1_k127_3619353_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004246 283.0
PYH1_k127_3619353_1 methyl-accepting chemotaxis K03406 - - 0.000459 52.0
PYH1_k127_3622594_0 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 463.0
PYH1_k127_3622594_1 L-glutamate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 439.0
PYH1_k127_3622594_2 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 353.0
PYH1_k127_3651849_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 491.0
PYH1_k127_3651849_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 453.0
PYH1_k127_3651849_2 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 443.0
PYH1_k127_3651849_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 341.0
PYH1_k127_3651849_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000006722 98.0
PYH1_k127_3680993_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
PYH1_k127_3680993_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 329.0
PYH1_k127_3680993_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 298.0
PYH1_k127_3680993_3 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 290.0
PYH1_k127_3680993_4 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003759 276.0
PYH1_k127_3680993_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000007131 235.0
PYH1_k127_3680993_6 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000001505 192.0
PYH1_k127_3680993_7 Glycosyl transferase family 2 - - - 0.000000000000006193 77.0
PYH1_k127_3680993_8 Lipid A core - O-antigen ligase and K02847 - - 0.000000001721 70.0
PYH1_k127_3734897_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1115.0
PYH1_k127_3734897_1 PFAM Acetyl-CoA hydrolase transferase K18122 - - 2.572e-296 921.0
PYH1_k127_3734897_2 Protein of unknown function, DUF255 K06888 - - 2.497e-236 747.0
PYH1_k127_3734897_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 353.0
PYH1_k127_3734897_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 321.0
PYH1_k127_3734897_5 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000002333 226.0
PYH1_k127_3734897_6 - - - - 0.000000000000000000002095 94.0
PYH1_k127_3734897_9 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0009201 45.0
PYH1_k127_3760442_0 response regulator receiver K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 397.0
PYH1_k127_3760442_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 352.0
PYH1_k127_3760442_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 343.0
PYH1_k127_3760442_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 286.0
PYH1_k127_3760442_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000007206 227.0
PYH1_k127_3760442_5 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001025 197.0
PYH1_k127_3760442_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000001661 152.0
PYH1_k127_3760442_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000002507 102.0
PYH1_k127_3760442_8 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000003202 77.0
PYH1_k127_3768863_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 348.0
PYH1_k127_3768863_1 Ftsk_gamma K03466 - - 0.00000000000000000381 84.0
PYH1_k127_3789694_0 K channel, inward rectifier, conserved region 2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 378.0
PYH1_k127_3789694_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
PYH1_k127_3789694_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003567 277.0
PYH1_k127_3789694_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 257.0
PYH1_k127_3789694_4 MarR family transcriptional K15973 - - 0.000000000000000000000000000000000000000000000007781 175.0
PYH1_k127_3789694_5 Translation initiation factor SUI1 K03113 - - 0.00000000000000000000001512 103.0
PYH1_k127_3789694_6 Transposase zinc-ribbon domain K07488 - - 0.00000004283 54.0
PYH1_k127_3789694_7 - - - - 0.0000003622 52.0
PYH1_k127_3803361_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 556.0
PYH1_k127_3803361_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 302.0
PYH1_k127_3803361_2 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000001308 169.0
PYH1_k127_3808436_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004279 259.0
PYH1_k127_3808436_1 - - - - 0.000000000006733 74.0
PYH1_k127_3825591_0 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 441.0
PYH1_k127_3825591_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000002416 239.0
PYH1_k127_3825591_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000008788 165.0
PYH1_k127_3830468_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.126e-209 660.0
PYH1_k127_3830468_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 391.0
PYH1_k127_3830468_10 CHASE3 domain - - - 0.0000008843 53.0
PYH1_k127_3830468_2 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 373.0
PYH1_k127_3830468_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 331.0
PYH1_k127_3830468_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000001403 179.0
PYH1_k127_3830468_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000005759 174.0
PYH1_k127_3830468_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000003435 156.0
PYH1_k127_3830468_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000001446 111.0
PYH1_k127_3830468_8 COG0784 FOG CheY-like receiver - - - 0.000000000008552 74.0
PYH1_k127_3830468_9 GGDEF domain - - - 0.00000002358 58.0
PYH1_k127_3867010_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1149.0
PYH1_k127_3867010_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 340.0
PYH1_k127_3867010_2 response to heat K07090 - - 0.000000000000000000000000000000000000000007294 156.0
PYH1_k127_3867010_3 GAF domain - - - 0.00000000003039 74.0
PYH1_k127_388840_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 9.288e-197 618.0
PYH1_k127_388840_1 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 436.0
PYH1_k127_388840_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 337.0
PYH1_k127_388840_3 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 318.0
PYH1_k127_388840_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001581 231.0
PYH1_k127_388840_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000013 225.0
PYH1_k127_388840_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000006726 162.0
PYH1_k127_3948375_0 ATP-grasp domain K01955 - 6.3.5.5 4.41e-199 626.0
PYH1_k127_3948375_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 387.0
PYH1_k127_3968840_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000099 278.0
PYH1_k127_3981409_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 598.0
PYH1_k127_3981409_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 331.0
PYH1_k127_3981409_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002583 232.0
PYH1_k127_3981409_3 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000008015 231.0
PYH1_k127_3981409_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000002377 204.0
PYH1_k127_3981409_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000006645 117.0
PYH1_k127_3982965_0 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 401.0
PYH1_k127_3982965_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 389.0
PYH1_k127_3982965_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 273.0
PYH1_k127_3982965_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000002636 96.0
PYH1_k127_3982965_4 PFAM DsrE family protein K07235 - - 0.00000001549 61.0
PYH1_k127_3982965_5 sulfur relay protein TusB DsrH K07237 - - 0.00000114 54.0
PYH1_k127_4002931_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 320.0
PYH1_k127_4002931_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000006983 186.0
PYH1_k127_4002931_2 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000008384 173.0
PYH1_k127_4002931_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000003344 89.0
PYH1_k127_4016670_0 TonB-dependent receptor - - - 0.00001786 52.0
PYH1_k127_4016670_1 HEAT repeat-containing protein - - - 0.00003418 56.0
PYH1_k127_4018335_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 599.0
PYH1_k127_4018335_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
PYH1_k127_4018335_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000003533 162.0
PYH1_k127_4056544_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001593 214.0
PYH1_k127_4056544_1 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000000001314 171.0
PYH1_k127_4056544_2 amine dehydrogenase activity - - - 0.0000000000000000001609 96.0
PYH1_k127_4061027_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 338.0
PYH1_k127_4061027_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 306.0
PYH1_k127_4061027_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006339 254.0
PYH1_k127_4061027_3 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000002805 237.0
PYH1_k127_4064785_0 Belongs to the GPI family K01810 - 5.3.1.9 2.756e-287 889.0
PYH1_k127_4064785_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000008048 257.0
PYH1_k127_4064785_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000003985 241.0
PYH1_k127_4064785_3 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000003087 203.0
PYH1_k127_4073181_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 516.0
PYH1_k127_4073181_2 CutA1 divalent ion tolerance protein K03926 - - 0.0000000004693 61.0
PYH1_k127_4178853_0 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000008681 164.0
PYH1_k127_4178853_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000007278 130.0
PYH1_k127_4178853_3 Predicted RNA-binding protein - - - 0.00000000000001198 75.0
PYH1_k127_4197570_0 Histidine kinase K07642,K18143 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 383.0
PYH1_k127_4197570_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 295.0
PYH1_k127_4197570_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000001114 102.0
PYH1_k127_4203875_0 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 507.0
PYH1_k127_4203875_1 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 443.0
PYH1_k127_4203875_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K05927,K06282,K18008 - 1.12.2.1,1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000005642 147.0
PYH1_k127_4203875_3 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000000001426 138.0
PYH1_k127_4213577_0 Protein conserved in bacteria - - - 7.554e-201 650.0
PYH1_k127_4213577_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 591.0
PYH1_k127_4213577_2 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 519.0
PYH1_k127_4213577_3 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 289.0
PYH1_k127_4213577_4 COG1522 Transcriptional regulators - - - 0.0000000003442 63.0
PYH1_k127_4213577_5 Type II secretion system protein B - - - 0.0002844 47.0
PYH1_k127_4220430_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.061e-219 686.0
PYH1_k127_4220430_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 542.0
PYH1_k127_4220430_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 524.0
PYH1_k127_4220430_3 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000008171 149.0
PYH1_k127_4220430_4 ThiS family K03636 - - 0.00000000000000000000000000000005825 128.0
PYH1_k127_4220430_5 NIL - - - 0.000000000000000000000000000006889 119.0
PYH1_k127_4220430_6 PFAM Type IV pilus assembly PilZ - - - 0.0005883 50.0
PYH1_k127_4221144_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 434.0
PYH1_k127_4221144_1 PFAM Bacterial protein of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 334.0
PYH1_k127_4221144_10 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000001438 153.0
PYH1_k127_4221144_11 Sulfurtransferase TusA - - - 0.000000000000000000000000004955 111.0
PYH1_k127_4221144_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000006797 115.0
PYH1_k127_4221144_13 - - - - 0.00000000000000000000000008366 111.0
PYH1_k127_4221144_14 Regulatory protein, FmdB family - - - 0.0000004889 54.0
PYH1_k127_4221144_15 Recombinase zinc beta ribbon domain - - - 0.000000653 53.0
PYH1_k127_4221144_16 - - - - 0.0000009881 50.0
PYH1_k127_4221144_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 315.0
PYH1_k127_4221144_3 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000001477 226.0
PYH1_k127_4221144_4 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000000004575 206.0
PYH1_k127_4221144_5 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000000000004388 204.0
PYH1_k127_4221144_6 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000001857 190.0
PYH1_k127_4221144_7 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000001576 181.0
PYH1_k127_4221144_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000005626 160.0
PYH1_k127_4221144_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000007852 155.0
PYH1_k127_4227546_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 516.0
PYH1_k127_4227546_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 323.0
PYH1_k127_4227546_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000001338 173.0
PYH1_k127_4241778_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000001099 199.0
PYH1_k127_4241778_1 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000001576 158.0
PYH1_k127_4241778_2 phosphorelay signal transduction system - - - 0.000000000000001337 81.0
PYH1_k127_4255636_0 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 375.0
PYH1_k127_4255636_1 DEAD DEAH box helicase K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000004752 248.0
PYH1_k127_4255636_2 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000008964 59.0
PYH1_k127_4256217_0 Aconitase C-terminal domain K01681 - 4.2.1.3 7.701e-296 921.0
PYH1_k127_4256217_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 532.0
PYH1_k127_4256217_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 446.0
PYH1_k127_4256217_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 324.0
PYH1_k127_4256217_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000003224 196.0
PYH1_k127_4256217_6 - - - - 0.00007671 46.0
PYH1_k127_4307476_0 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 286.0
PYH1_k127_4307476_1 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000001266 158.0
PYH1_k127_4307476_2 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000002434 104.0
PYH1_k127_4348016_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 573.0
PYH1_k127_4349175_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 290.0
PYH1_k127_4349175_1 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007491 219.0
PYH1_k127_4349175_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000003449 171.0
PYH1_k127_4349175_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000001732 114.0
PYH1_k127_4349175_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000002662 68.0
PYH1_k127_435527_0 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000004338 206.0
PYH1_k127_435527_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000003129 180.0
PYH1_k127_435527_2 MlaD protein K02067 - - 0.00000000000000000000000000000004544 134.0
PYH1_k127_4362468_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 358.0
PYH1_k127_4362468_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000003997 238.0
PYH1_k127_4362468_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000276 211.0
PYH1_k127_4362468_3 cyclopropane-fatty-acyl-phospholipid synthase K00568 - 2.1.1.222,2.1.1.64 0.00002046 53.0
PYH1_k127_4372631_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.293e-211 666.0
PYH1_k127_4372631_1 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 271.0
PYH1_k127_4372631_2 Ribonuclease E/G family K08300 - 3.1.26.12 0.000000000000000000000000000000000000438 144.0
PYH1_k127_4372631_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000004115 67.0
PYH1_k127_4378393_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 400.0
PYH1_k127_4378393_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000005072 232.0
PYH1_k127_4378393_2 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000002308 119.0
PYH1_k127_4449875_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.274e-215 674.0
PYH1_k127_4449875_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 361.0
PYH1_k127_4449875_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001437 67.0
PYH1_k127_4449875_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 319.0
PYH1_k127_4449875_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 287.0
PYH1_k127_4449875_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000001299 202.0
PYH1_k127_4449875_5 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001347 181.0
PYH1_k127_4449875_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000003412 177.0
PYH1_k127_4449875_7 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001905 171.0
PYH1_k127_4449875_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000003591 164.0
PYH1_k127_4449875_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000008081 134.0
PYH1_k127_4462624_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.295e-229 745.0
PYH1_k127_4462624_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 341.0
PYH1_k127_4462624_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000006074 206.0
PYH1_k127_4462624_3 PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000005576 142.0
PYH1_k127_4462624_4 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000006114 141.0
PYH1_k127_4462624_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001584 145.0
PYH1_k127_4477147_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 332.0
PYH1_k127_4477147_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
PYH1_k127_4477147_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000003852 198.0
PYH1_k127_4477147_3 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000005092 184.0
PYH1_k127_4477147_4 oligoendopeptidase F K08602 - - 0.0000000000000000000000000000000000000009405 156.0
PYH1_k127_4477147_5 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000001807 148.0
PYH1_k127_4477147_6 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000002433 148.0
PYH1_k127_4477147_7 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000504 85.0
PYH1_k127_4477147_8 signal transduction protein with EFhand domain - - - 0.00001771 48.0
PYH1_k127_4481562_0 General secretory system II, protein E domain protein K02652 - - 7.489e-219 694.0
PYH1_k127_4481562_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 535.0
PYH1_k127_4481562_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 463.0
PYH1_k127_4481562_3 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 460.0
PYH1_k127_4481562_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 371.0
PYH1_k127_4481562_5 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002788 293.0
PYH1_k127_4481562_6 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000048 261.0
PYH1_k127_4524191_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 357.0
PYH1_k127_4524191_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004208 258.0
PYH1_k127_4524191_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000005208 240.0
PYH1_k127_4524191_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
PYH1_k127_4524191_4 - - - - 0.0000000000000000000000000001973 117.0
PYH1_k127_4524191_5 serine-type endopeptidase activity K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000002342 79.0
PYH1_k127_4600378_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 343.0
PYH1_k127_4600378_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003023 267.0
PYH1_k127_4600378_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001519 217.0
PYH1_k127_4600378_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000114 145.0
PYH1_k127_4600378_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000001732 114.0
PYH1_k127_4600378_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000001585 80.0
PYH1_k127_4600378_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000006944 63.0
PYH1_k127_4638619_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 527.0
PYH1_k127_4638619_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 383.0
PYH1_k127_4638619_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 387.0
PYH1_k127_4638619_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
PYH1_k127_4638619_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 306.0
PYH1_k127_4638619_5 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 287.0
PYH1_k127_4638619_6 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000006196 221.0
PYH1_k127_4638619_7 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000001833 184.0
PYH1_k127_4638619_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000006877 57.0
PYH1_k127_4642925_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 474.0
PYH1_k127_4642925_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 402.0
PYH1_k127_4642925_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 256.0
PYH1_k127_4642925_3 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000003161 241.0
PYH1_k127_4642925_4 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000004754 147.0
PYH1_k127_4642925_5 Uncharacterized conserved protein (DUF2249) K07322 - - 0.0000000000000000000000000006029 115.0
PYH1_k127_4642925_6 Domain of unknown function (DUF1858) - - - 0.000000000000000000001167 96.0
PYH1_k127_4642925_7 4Fe-4S binding domain - - - 0.00001681 48.0
PYH1_k127_464985_0 Aconitase C-terminal domain K01681 - 4.2.1.3 3.207e-233 729.0
PYH1_k127_464985_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 363.0
PYH1_k127_464985_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 324.0
PYH1_k127_464985_3 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000000000000000008076 221.0
PYH1_k127_464985_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000001694 194.0
PYH1_k127_464985_5 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000008439 174.0
PYH1_k127_464985_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000005685 135.0
PYH1_k127_464985_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000002419 71.0
PYH1_k127_4651954_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1022.0
PYH1_k127_4651954_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 381.0
PYH1_k127_4651954_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000006869 127.0
PYH1_k127_4651954_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000007544 97.0
PYH1_k127_4651954_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000001419 88.0
PYH1_k127_4651954_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000005983 72.0
PYH1_k127_4655656_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.294e-275 853.0
PYH1_k127_4655656_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 584.0
PYH1_k127_4655656_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 468.0
PYH1_k127_4655656_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 324.0
PYH1_k127_4655656_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 292.0
PYH1_k127_4655656_5 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000002604 230.0
PYH1_k127_4655656_6 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000004098 175.0
PYH1_k127_4655656_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000001471 134.0
PYH1_k127_4655656_8 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000001744 99.0
PYH1_k127_4668204_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.24e-273 854.0
PYH1_k127_4668204_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 516.0
PYH1_k127_4668204_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 447.0
PYH1_k127_4668204_3 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 325.0
PYH1_k127_4668204_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000005969 209.0
PYH1_k127_4668204_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000001691 196.0
PYH1_k127_4668204_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000001093 159.0
PYH1_k127_4668221_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000003719 237.0
PYH1_k127_4668221_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000001505 167.0
PYH1_k127_4668221_2 SMART Elongator protein 3 MiaB NifB K22226 - - 0.0000000000000000000000000000000000000000005887 160.0
PYH1_k127_467728_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 5.508e-243 761.0
PYH1_k127_4717993_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.727e-275 861.0
PYH1_k127_4717993_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
PYH1_k127_4717993_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 400.0
PYH1_k127_4717993_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 398.0
PYH1_k127_4717993_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
PYH1_k127_4717993_5 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000006241 233.0
PYH1_k127_4717993_6 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000000000000004259 155.0
PYH1_k127_4736207_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1107.0
PYH1_k127_4736207_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001881 269.0
PYH1_k127_4736207_2 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003251 268.0
PYH1_k127_4736207_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000002512 207.0
PYH1_k127_4736207_4 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000001883 147.0
PYH1_k127_4736207_5 Protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000000007666 149.0
PYH1_k127_4736207_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000004238 144.0
PYH1_k127_4736207_7 Iron-sulfur cluster-binding domain - - - 0.000003131 58.0
PYH1_k127_4736207_8 Belongs to the 'phage' integrase family - - - 0.0001193 46.0
PYH1_k127_4737216_0 FecR protein - - - 0.0 1126.0
PYH1_k127_4737216_1 CHASE2 K01768 - 4.6.1.1 3.469e-216 688.0
PYH1_k127_4737216_2 heat shock protein binding - - - 0.000000000000000000000000000000000001834 149.0
PYH1_k127_4854022_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 386.0
PYH1_k127_4854022_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
PYH1_k127_4854022_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000002211 200.0
PYH1_k127_4854022_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000001959 136.0
PYH1_k127_4854022_4 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000000001879 123.0
PYH1_k127_4854022_5 Tetratricopeptide repeat - - - 0.00000000000000000000009066 110.0
PYH1_k127_4854022_6 Roadblock/LC7 domain - - - 0.0001525 47.0
PYH1_k127_4882073_0 4Fe-4S dicluster domain - - - 1.019e-291 902.0
PYH1_k127_4882073_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 551.0
PYH1_k127_4882073_2 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 444.0
PYH1_k127_4882073_3 4 iron, 4 sulfur cluster binding K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 362.0
PYH1_k127_4882073_4 - - - - 0.0000000000000000000000000000000000000000000000000001858 188.0
PYH1_k127_4882073_5 4Fe-4S binding domain - - - 0.00000000000004836 73.0
PYH1_k127_4882073_6 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000007223 59.0
PYH1_k127_4892345_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 578.0
PYH1_k127_4892345_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 488.0
PYH1_k127_4892345_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 416.0
PYH1_k127_4892345_3 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 371.0
PYH1_k127_4892345_4 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 326.0
PYH1_k127_4892345_5 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007734 265.0
PYH1_k127_4892345_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000006771 164.0
PYH1_k127_4892345_7 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000002612 162.0
PYH1_k127_491272_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 352.0
PYH1_k127_491272_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 342.0
PYH1_k127_491272_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006289 282.0
PYH1_k127_491272_3 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000002441 238.0
PYH1_k127_491272_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000226 167.0
PYH1_k127_4929740_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.406e-243 779.0
PYH1_k127_4929740_1 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 494.0
PYH1_k127_4929740_10 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000000000000000001825 206.0
PYH1_k127_4929740_11 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000009868 187.0
PYH1_k127_4929740_12 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000002093 132.0
PYH1_k127_4929740_13 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000002959 117.0
PYH1_k127_4929740_14 PFAM thioesterase superfamily K02614 - - 0.0000000000000007214 83.0
PYH1_k127_4929740_15 Beta-lactamase - - - 0.0000001104 57.0
PYH1_k127_4929740_2 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 378.0
PYH1_k127_4929740_3 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 335.0
PYH1_k127_4929740_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
PYH1_k127_4929740_5 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
PYH1_k127_4929740_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 292.0
PYH1_k127_4929740_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 289.0
PYH1_k127_4929740_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000001576 246.0
PYH1_k127_4929740_9 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000001902 234.0
PYH1_k127_4975905_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 349.0
PYH1_k127_4975905_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000001433 58.0
PYH1_k127_4981443_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1382.0
PYH1_k127_4981443_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 538.0
PYH1_k127_4981443_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000001954 159.0
PYH1_k127_4981443_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000001005 145.0
PYH1_k127_4981443_4 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000003949 109.0
PYH1_k127_4981443_5 protein complex oligomerization - - - 0.0000000000000000000002155 106.0
PYH1_k127_4981443_7 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000006032 54.0
PYH1_k127_4989179_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 344.0
PYH1_k127_4989179_1 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 295.0
PYH1_k127_4989179_2 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
PYH1_k127_4989179_3 Helix-turn-helix domain - - - 0.000000000000000000004038 102.0
PYH1_k127_4989179_4 Radical SAM superfamily K03639 - 4.1.99.22 0.0000000000000000007072 96.0
PYH1_k127_4989179_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000002528 64.0
PYH1_k127_4989179_6 - - - - 0.00001286 55.0
PYH1_k127_4989179_7 family 9 - - - 0.00009355 52.0
PYH1_k127_499958_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 454.0
PYH1_k127_499979_0 Peptidase family M28 - - - 1.138e-220 705.0
PYH1_k127_499979_1 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
PYH1_k127_499979_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000001632 192.0
PYH1_k127_499979_3 gas vesicle protein - - - 0.00000000000000000005805 94.0
PYH1_k127_499979_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000005941 86.0
PYH1_k127_5016339_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 2.032e-226 715.0
PYH1_k127_5016339_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 443.0
PYH1_k127_5016339_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000001634 57.0
PYH1_k127_5074233_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000001151 174.0
PYH1_k127_5074233_1 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000006138 160.0
PYH1_k127_5074233_2 IMP dehydrogenase activity - - - 0.0000000000000000000000000000003686 128.0
PYH1_k127_5080039_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.095e-318 985.0
PYH1_k127_5080039_1 K transport systems K10716 - - 0.000000000000000000000000000000000000000000000004761 175.0
PYH1_k127_5080039_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000004474 128.0
PYH1_k127_5082713_0 GTP-binding protein TypA K06207 - - 2.784e-266 831.0
PYH1_k127_5082713_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 597.0
PYH1_k127_5082713_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000003196 225.0
PYH1_k127_5116122_0 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007613 254.0
PYH1_k127_5116122_1 PFAM Cache, type 2 - - - 0.00000000000000000000000000000000000000000000008597 173.0
PYH1_k127_5116122_2 PFAM chemotaxis K03406 - - 0.00000000000000000000000000000000000006516 147.0
PYH1_k127_5116122_3 Four helix bundle sensory module for signal transduction K03406,K03776,K05875 - - 0.00000000009909 70.0
PYH1_k127_5125822_0 Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 488.0
PYH1_k127_5125822_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 356.0
PYH1_k127_5125822_2 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
PYH1_k127_5125822_3 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
PYH1_k127_5125822_4 Ecotin K08276 - - 0.000000000000000000000000000000000000000000000000000000000002771 212.0
PYH1_k127_5125822_5 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000005309 104.0
PYH1_k127_5125822_7 chaperone-mediated protein complex assembly K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000004767 79.0
PYH1_k127_5125822_8 Belongs to the HesB IscA family K15724 - - 0.00000004596 56.0
PYH1_k127_5125822_9 Cytochrome C oxidase subunit II, periplasmic domain protein K00376 - 1.7.2.4 0.00000006489 60.0
PYH1_k127_5131156_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.391e-261 817.0
PYH1_k127_5131156_1 membrane K09133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 345.0
PYH1_k127_5131156_2 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.000000000004829 69.0
PYH1_k127_5131156_3 Recombinase - - - 0.0000747 47.0
PYH1_k127_5137519_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 397.0
PYH1_k127_5137519_1 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.00000000000000000000000000000001154 134.0
PYH1_k127_5166219_0 4Fe-4S binding domain - - - 4.018e-227 713.0
PYH1_k127_5166219_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000173 167.0
PYH1_k127_5166219_2 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000306 153.0
PYH1_k127_5174227_0 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 343.0
PYH1_k127_5174227_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 337.0
PYH1_k127_5174227_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000001309 148.0
PYH1_k127_5176006_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1058.0
PYH1_k127_5176006_1 - - - - 0.0000000000000000000000000000002156 126.0
PYH1_k127_5184667_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 320.0
PYH1_k127_5184667_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000008172 221.0
PYH1_k127_5184667_2 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000001652 209.0
PYH1_k127_5184667_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000004326 154.0
PYH1_k127_5184667_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000513 119.0
PYH1_k127_5184667_6 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000008789 107.0
PYH1_k127_5184667_7 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000316 108.0
PYH1_k127_5187171_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1516.0
PYH1_k127_5187171_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 374.0
PYH1_k127_5204567_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 542.0
PYH1_k127_5204567_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 424.0
PYH1_k127_5204567_2 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 333.0
PYH1_k127_5204567_3 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 292.0
PYH1_k127_5204567_4 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006455 289.0
PYH1_k127_5204567_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0006261 53.0
PYH1_k127_5225484_0 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000002505 245.0
PYH1_k127_5250040_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 606.0
PYH1_k127_5250040_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 456.0
PYH1_k127_5250040_2 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 416.0
PYH1_k127_5250040_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000006025 219.0
PYH1_k127_5250040_4 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000002297 167.0
PYH1_k127_5261753_0 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 433.0
PYH1_k127_5261753_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004675 252.0
PYH1_k127_5261753_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000008648 120.0
PYH1_k127_5272664_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.485e-299 931.0
PYH1_k127_5272664_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 6.564e-268 843.0
PYH1_k127_5272664_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 501.0
PYH1_k127_5272664_3 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 283.0
PYH1_k127_5272664_4 - - - - 0.000000000000000000000000000000000000000000000000003917 186.0
PYH1_k127_5311139_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 443.0
PYH1_k127_5311139_1 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000005468 187.0
PYH1_k127_5311139_2 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000002533 60.0
PYH1_k127_5312405_0 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 572.0
PYH1_k127_5312405_1 sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 427.0
PYH1_k127_5312405_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 365.0
PYH1_k127_5312405_3 Prokaryotic N-terminal methylation motif - - - 0.000009327 55.0
PYH1_k127_5312405_4 Prokaryotic N-terminal methylation motif K02458 - - 0.0009897 48.0
PYH1_k127_5345742_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.138e-279 869.0
PYH1_k127_5345742_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.206e-260 815.0
PYH1_k127_5345742_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 359.0
PYH1_k127_5345742_11 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 330.0
PYH1_k127_5345742_12 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 304.0
PYH1_k127_5345742_13 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002275 275.0
PYH1_k127_5345742_14 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
PYH1_k127_5345742_15 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000053 261.0
PYH1_k127_5345742_16 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000002114 204.0
PYH1_k127_5345742_17 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000001646 181.0
PYH1_k127_5345742_18 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000004531 166.0
PYH1_k127_5345742_19 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000002253 152.0
PYH1_k127_5345742_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.636e-249 779.0
PYH1_k127_5345742_20 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000000004608 147.0
PYH1_k127_5345742_22 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.00000000000000000000000285 105.0
PYH1_k127_5345742_23 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000009883 88.0
PYH1_k127_5345742_26 - - - - 0.0003371 47.0
PYH1_k127_5345742_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.48e-209 660.0
PYH1_k127_5345742_4 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 587.0
PYH1_k127_5345742_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 538.0
PYH1_k127_5345742_6 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 522.0
PYH1_k127_5345742_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 459.0
PYH1_k127_5345742_8 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 442.0
PYH1_k127_5345742_9 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 378.0
PYH1_k127_5349349_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 492.0
PYH1_k127_5349349_1 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
PYH1_k127_5349349_2 phosphorelay signal transduction system - - - 0.00000000000000278 81.0
PYH1_k127_5394748_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 519.0
PYH1_k127_5394748_1 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 389.0
PYH1_k127_5394748_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 386.0
PYH1_k127_5394748_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 354.0
PYH1_k127_5394748_4 Cell wall formation K00075 - 1.3.1.98 0.0000000000000008686 80.0
PYH1_k127_5410625_0 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 363.0
PYH1_k127_5410625_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000003942 139.0
PYH1_k127_5410625_2 UDP-N-acetylmuramate dehydrogenase activity K00075,K01921 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 0.0000000000000000000007301 96.0
PYH1_k127_5410625_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000001759 63.0
PYH1_k127_5415559_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 429.0
PYH1_k127_5415559_1 COGs COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - - 0.00000000000000000000002364 115.0
PYH1_k127_5415559_2 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000002134 75.0
PYH1_k127_5415559_3 Universal stress protein family - - - 0.0000000008051 68.0
PYH1_k127_5430976_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 529.0
PYH1_k127_5430976_1 YbbR-like protein - - - 0.00000000000000000000000000000000000009869 149.0
PYH1_k127_5430976_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000003329 65.0
PYH1_k127_5449359_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 377.0
PYH1_k127_5449359_1 Belongs to the peptidase M16 family - - - 0.00000000000000000000008948 102.0
PYH1_k127_5449359_2 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000004367 48.0
PYH1_k127_5451321_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 509.0
PYH1_k127_5451321_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000005416 141.0
PYH1_k127_5451321_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000001263 106.0
PYH1_k127_5475760_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 517.0
PYH1_k127_5475760_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003433 284.0
PYH1_k127_5475760_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000002444 185.0
PYH1_k127_5475760_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000001056 132.0
PYH1_k127_5493382_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.529e-219 688.0
PYH1_k127_5493382_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008507 235.0
PYH1_k127_5493382_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000004699 164.0
PYH1_k127_5493382_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000005545 161.0
PYH1_k127_5493382_4 reductase K00059 - 1.1.1.100 0.000000000000003802 76.0
PYH1_k127_5551500_0 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
PYH1_k127_5551500_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000003333 181.0
PYH1_k127_5551500_2 electron transfer activity K05337,K17247 - - 0.0000000000000000000000000002911 114.0
PYH1_k127_5551500_3 Cupin 2, conserved barrel domain protein - - - 0.00000000004313 68.0
PYH1_k127_5551500_4 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000557 56.0
PYH1_k127_562027_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 315.0
PYH1_k127_562027_1 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000007304 223.0
PYH1_k127_562027_2 ABC transporter, ATP-binding protein K16786,K16787 - - 0.00003024 47.0
PYH1_k127_5668508_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1644.0
PYH1_k127_5668508_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1201.0
PYH1_k127_5668508_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000009501 194.0
PYH1_k127_5681947_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 588.0
PYH1_k127_5681947_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000984 267.0
PYH1_k127_5681947_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000001014 166.0
PYH1_k127_5681947_3 - - - - 0.0000000000000000007329 93.0
PYH1_k127_5691610_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1061.0
PYH1_k127_5691610_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 485.0
PYH1_k127_5691610_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 326.0
PYH1_k127_5691610_3 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 295.0
PYH1_k127_5691610_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 269.0
PYH1_k127_5697154_0 Elongation factor G, domain IV K02355 - - 5.845e-308 957.0
PYH1_k127_5697154_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000001122 174.0
PYH1_k127_5697154_2 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000004088 63.0
PYH1_k127_5703154_0 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 372.0
PYH1_k127_5703154_1 Pilus assembly protein, PilP K02665 - - 0.000000002186 63.0
PYH1_k127_5732577_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 475.0
PYH1_k127_5732577_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 396.0
PYH1_k127_5732577_2 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000001929 234.0
PYH1_k127_5732577_3 Response regulator receiver - - - 0.00000000000000000000000000000003521 129.0
PYH1_k127_5732577_4 photoreceptor activity - - - 0.00000000000003083 87.0
PYH1_k127_5732577_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00001881 53.0
PYH1_k127_5761767_0 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 427.0
PYH1_k127_5761767_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 414.0
PYH1_k127_5761767_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 351.0
PYH1_k127_5761767_3 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 315.0
PYH1_k127_5761767_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000217 295.0
PYH1_k127_5761767_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000002611 241.0
PYH1_k127_5761767_6 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000001259 212.0
PYH1_k127_5761767_8 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000003864 79.0
PYH1_k127_5761767_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000001623 62.0
PYH1_k127_5799573_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 428.0
PYH1_k127_5799573_1 Appr-1'-p processing enzyme - - - 0.000000000000000000000000001689 113.0
PYH1_k127_5822194_0 COG3209 Rhs family protein - - - 0.00000000000000000000001719 114.0
PYH1_k127_5822194_1 Hep Hag repeat protein - - - 0.000000000000000005986 97.0
PYH1_k127_5822194_2 Belongs to the peptidase S8 family - - - 0.0000000001378 69.0
PYH1_k127_58741_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 0.0 1054.0
PYH1_k127_58741_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 350.0
PYH1_k127_58741_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000002107 153.0
PYH1_k127_58741_3 Nitrate reductase delta subunit - - - 0.00000000000000000000000007589 117.0
PYH1_k127_58741_4 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000002565 64.0
PYH1_k127_5875074_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.214e-318 992.0
PYH1_k127_5875074_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 5.362e-238 758.0
PYH1_k127_5875074_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 438.0
PYH1_k127_5875074_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000356 264.0
PYH1_k127_5875074_4 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000101 158.0
PYH1_k127_5875074_5 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000001318 154.0
PYH1_k127_5875074_6 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000001905 155.0
PYH1_k127_5875074_7 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000002232 140.0
PYH1_k127_5875074_8 transcriptional regulator - - - 0.00000000009225 67.0
PYH1_k127_5878062_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 349.0
PYH1_k127_5878062_1 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000001073 144.0
PYH1_k127_5878062_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000005842 143.0
PYH1_k127_5878522_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 531.0
PYH1_k127_5878522_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 345.0
PYH1_k127_5878522_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000008836 129.0
PYH1_k127_5878522_3 - - - - 0.00000000003777 68.0
PYH1_k127_5901375_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 470.0
PYH1_k127_5901375_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 287.0
PYH1_k127_5901375_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000239 161.0
PYH1_k127_5905033_0 - - - - 0.00000000000000000000000000000000000000000000000000000000003541 207.0
PYH1_k127_5905033_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000002034 196.0
PYH1_k127_5905033_2 Histidine Phosphotransfer domain - - - 0.00004781 50.0
PYH1_k127_5918801_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 484.0
PYH1_k127_5918801_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 334.0
PYH1_k127_5918801_2 PFAM diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000000000000000000000000000000000000003658 186.0
PYH1_k127_5918801_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000002165 106.0
PYH1_k127_5918801_4 - - - - 0.0000000000000000000001696 103.0
PYH1_k127_5918801_5 PFAM Stage II sporulation K06381 - - 0.0000000000000002848 79.0
PYH1_k127_5918801_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01448,K02519 - 3.5.1.28 0.00001698 54.0
PYH1_k127_5926948_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 538.0
PYH1_k127_5926948_1 heat shock protein binding K05516,K05801 - - 0.00000000000000000049 95.0
PYH1_k127_5926948_2 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000531 85.0
PYH1_k127_5949787_0 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 370.0
PYH1_k127_5949787_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001324 284.0
PYH1_k127_5949787_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003651 282.0
PYH1_k127_5949787_3 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000002422 152.0
PYH1_k127_5949787_4 PglZ domain - - - 0.00008369 49.0
PYH1_k127_5988614_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 562.0
PYH1_k127_5988614_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 484.0
PYH1_k127_5988614_2 Involved in the tonB-independent uptake of proteins K13669 - - 0.000004406 57.0
PYH1_k127_5997677_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.348e-285 900.0
PYH1_k127_5997677_1 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000002175 194.0
PYH1_k127_5997677_2 Belongs to the pirin family K06911 - - 0.00000000000000002731 81.0
PYH1_k127_5997677_3 PFAM DsrE DsrF-like family - - - 0.000000000864 64.0
PYH1_k127_5997677_4 - - - - 0.000008596 49.0
PYH1_k127_6015421_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.03e-255 806.0
PYH1_k127_6015421_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000138 115.0
PYH1_k127_6015421_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000152 50.0
PYH1_k127_6016189_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 603.0
PYH1_k127_6016189_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 550.0
PYH1_k127_6016189_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 521.0
PYH1_k127_6016189_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 424.0
PYH1_k127_6016189_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000001638 131.0
PYH1_k127_6016189_5 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000009818 131.0
PYH1_k127_6016189_6 RDD family - - - 0.00000000000000000000000005368 113.0
PYH1_k127_6016189_7 lyase activity - - - 0.0000000000000002952 81.0
PYH1_k127_6016189_8 shape-determining protein MreD K03571 - - 0.0000001742 59.0
PYH1_k127_6049058_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1146.0
PYH1_k127_6049058_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 5.061e-314 966.0
PYH1_k127_6049058_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000002608 151.0
PYH1_k127_6049058_3 Epimerase K07071 - - 0.00000000000000002031 83.0
PYH1_k127_6071344_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.528e-289 903.0
PYH1_k127_6071344_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.408e-257 815.0
PYH1_k127_6071344_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 438.0
PYH1_k127_6071344_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 397.0
PYH1_k127_6071344_4 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 332.0
PYH1_k127_6071344_5 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 314.0
PYH1_k127_6071344_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000004201 220.0
PYH1_k127_6071344_7 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000283 153.0
PYH1_k127_6071344_8 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000000000007779 157.0
PYH1_k127_6071344_9 Uncharacterised protein family UPF0047 - - - 0.0000000007581 60.0
PYH1_k127_6074152_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 506.0
PYH1_k127_6074152_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000008603 117.0
PYH1_k127_6090020_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1061.0
PYH1_k127_6090020_1 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 351.0
PYH1_k127_6090020_2 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000007651 68.0
PYH1_k127_6101315_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000007478 237.0
PYH1_k127_6101315_1 ABC transporter substrate binding protein K01989 - - 0.00000007931 62.0
PYH1_k127_6101315_2 Histidine kinase - - - 0.000001536 58.0
PYH1_k127_6102702_0 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 368.0
PYH1_k127_6102702_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 322.0
PYH1_k127_6102702_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 303.0
PYH1_k127_610606_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 388.0
PYH1_k127_610606_1 Trypsin K04771 - 3.4.21.107 0.0000003043 59.0
PYH1_k127_6113207_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 4.491e-201 632.0
PYH1_k127_6113207_1 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000004542 201.0
PYH1_k127_6113207_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000298 152.0
PYH1_k127_6113207_3 Transglutaminase/protease-like homologues - - - 0.000000000000000001716 91.0
PYH1_k127_6119301_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.615e-221 698.0
PYH1_k127_6119301_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 362.0
PYH1_k127_6119301_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 362.0
PYH1_k127_6119301_3 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 316.0
PYH1_k127_6119301_4 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
PYH1_k127_6119301_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000009585 195.0
PYH1_k127_6119301_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000004066 154.0
PYH1_k127_6119301_7 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000008726 144.0
PYH1_k127_6119301_8 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000000001716 110.0
PYH1_k127_6161051_0 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004681 267.0
PYH1_k127_6161051_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004646 235.0
PYH1_k127_6161051_2 DUF167 K09131 - - 0.0000000000000000000000000000000000000000000000000000000004447 213.0
PYH1_k127_6161051_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000009582 205.0
PYH1_k127_6161051_4 YacP-like NYN domain K06962 - - 0.00000000000000000000174 102.0
PYH1_k127_6161051_5 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000003935 82.0
PYH1_k127_6161051_6 Belongs to the UPF0235 family K09131 - - 0.00000004477 57.0
PYH1_k127_6179143_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 406.0
PYH1_k127_6179143_1 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 344.0
PYH1_k127_6219506_0 Belongs to the 'phage' integrase family - - - 0.0000184 48.0
PYH1_k127_621954_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000004648 238.0
PYH1_k127_621954_1 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000001051 148.0
PYH1_k127_621954_2 - - - - 0.000000000584 70.0
PYH1_k127_6231632_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
PYH1_k127_6231632_1 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000002932 205.0
PYH1_k127_6231632_2 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000001882 166.0
PYH1_k127_6231632_3 PFAM MOSC domain - - - 0.000000000000000000000000000000000000003549 147.0
PYH1_k127_6231632_5 Regulatory protein, FmdB family - - - 0.000000000000000001075 87.0
PYH1_k127_6249537_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 480.0
PYH1_k127_6249537_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003904 257.0
PYH1_k127_6249537_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
PYH1_k127_6249537_3 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000002206 210.0
PYH1_k127_6249537_4 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000652 158.0
PYH1_k127_6249537_5 - - - - 0.0000000000000000000000000000000000000005017 155.0
PYH1_k127_6249537_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000002287 148.0
PYH1_k127_6249537_7 - - - - 0.000000000000000001146 91.0
PYH1_k127_6253823_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 507.0
PYH1_k127_6253823_1 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 497.0
PYH1_k127_6255548_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 447.0
PYH1_k127_6255548_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000002269 235.0
PYH1_k127_6255548_2 Protein of unknown function DUF72 - - - 0.0000000000000000000002634 99.0
PYH1_k127_6255548_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.0005343 46.0
PYH1_k127_6264438_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.163e-223 699.0
PYH1_k127_6264438_1 rubredoxin - - - 0.0000000000000000000000007173 104.0
PYH1_k127_6264438_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000006311 71.0
PYH1_k127_6284430_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.431e-256 807.0
PYH1_k127_6284430_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008512 237.0
PYH1_k127_6284430_2 PFAM PSP1 domain protein - - - 0.0000000001559 68.0
PYH1_k127_6293070_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 2.341e-232 737.0
PYH1_k127_6293070_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 374.0
PYH1_k127_6293070_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 365.0
PYH1_k127_6293070_3 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 383.0
PYH1_k127_6293070_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001492 251.0
PYH1_k127_6293070_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.000000000000000000000000000000000000000000004314 167.0
PYH1_k127_6293070_6 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000001303 170.0
PYH1_k127_6293070_7 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000003177 162.0
PYH1_k127_6312896_0 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 579.0
PYH1_k127_6312896_1 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 288.0
PYH1_k127_6312896_2 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
PYH1_k127_6312896_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
PYH1_k127_6312896_4 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000007358 224.0
PYH1_k127_6312896_5 - - - - 0.0000000000000000000000000000000000000000008309 162.0
PYH1_k127_6312896_6 PFAM Methylamine - - - 0.0000000000000009577 84.0
PYH1_k127_6312896_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000003988 61.0
PYH1_k127_6312896_8 Redoxin - - - 0.0002104 48.0
PYH1_k127_6330169_0 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001937 256.0
PYH1_k127_6330169_1 - - - - 0.000000000000000000000003474 114.0
PYH1_k127_6337910_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 398.0
PYH1_k127_6337910_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000006996 244.0
PYH1_k127_6337910_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000001312 164.0
PYH1_k127_6390999_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 436.0
PYH1_k127_6390999_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 401.0
PYH1_k127_6390999_2 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000001526 217.0
PYH1_k127_6395833_0 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 411.0
PYH1_k127_6395833_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 298.0
PYH1_k127_6395833_2 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.0000000000003259 71.0
PYH1_k127_6395833_3 peptidyl-tyrosine sulfation - - - 0.00000008147 61.0
PYH1_k127_6490568_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 5.913e-211 665.0
PYH1_k127_6490568_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 405.0
PYH1_k127_6490568_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000008591 246.0
PYH1_k127_6490568_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
PYH1_k127_6490568_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000003501 221.0
PYH1_k127_6490568_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000001946 199.0
PYH1_k127_6490568_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000001167 185.0
PYH1_k127_6490568_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000002722 127.0
PYH1_k127_6493378_0 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000009822 218.0
PYH1_k127_6493378_1 - - - - 0.000000000000000002119 91.0
PYH1_k127_6493378_2 3-deoxy-7-phosphoheptulonate synthase activity K03856 - 2.5.1.54 0.00000000001711 66.0
PYH1_k127_6512632_0 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 531.0
PYH1_k127_6512632_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 361.0
PYH1_k127_6512632_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000004698 64.0
PYH1_k127_655457_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 602.0
PYH1_k127_655457_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 323.0
PYH1_k127_655457_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000008794 231.0
PYH1_k127_655457_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000004147 217.0
PYH1_k127_655457_4 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000005538 147.0
PYH1_k127_655457_5 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000003333 103.0
PYH1_k127_6561091_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 556.0
PYH1_k127_6561091_1 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 349.0
PYH1_k127_6561091_10 cyclic nucleotide-binding - - - 0.0000000000000004638 84.0
PYH1_k127_6561091_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001804 275.0
PYH1_k127_6561091_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001535 215.0
PYH1_k127_6561091_4 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000283 203.0
PYH1_k127_6561091_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000007357 185.0
PYH1_k127_6561091_6 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000003533 162.0
PYH1_k127_6561091_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000001435 148.0
PYH1_k127_6561091_8 sigma factor antagonist activity K20977 - - 0.00000000000000000000000000113 116.0
PYH1_k127_6561091_9 DRTGG domain - - - 0.000000000000000000000000001361 115.0
PYH1_k127_6619776_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.466e-221 690.0
PYH1_k127_6619776_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 437.0
PYH1_k127_6619776_2 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 383.0
PYH1_k127_6619776_3 - - - - 0.00000000000000000000000000000004239 144.0
PYH1_k127_6658687_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 333.0
PYH1_k127_6658687_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000001665 217.0
PYH1_k127_6729378_0 Elongation factor SelB, winged helix K03833 - - 2.589e-209 669.0
PYH1_k127_6729378_1 OsmC-like protein K07397 - - 0.000000000000000000000001036 109.0
PYH1_k127_6729378_2 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000003162 98.0
PYH1_k127_6729378_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000006764 51.0
PYH1_k127_6730666_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 511.0
PYH1_k127_6730666_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 357.0
PYH1_k127_6730666_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000003422 242.0
PYH1_k127_6730666_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000003513 86.0
PYH1_k127_6733491_0 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 2.238e-209 655.0
PYH1_k127_6733491_1 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 6.63e-196 614.0
PYH1_k127_6733491_2 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 332.0
PYH1_k127_6742062_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 441.0
PYH1_k127_6742062_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 361.0
PYH1_k127_6742062_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 319.0
PYH1_k127_6742062_3 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000006488 238.0
PYH1_k127_6742062_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000004956 163.0
PYH1_k127_6742062_5 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000007222 148.0
PYH1_k127_6742181_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 427.0
PYH1_k127_6742181_1 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000008576 201.0
PYH1_k127_6742181_2 PFAM CBS domain K07182 - - 0.000000000000000000000532 101.0
PYH1_k127_6751363_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 491.0
PYH1_k127_6751363_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005847 276.0
PYH1_k127_6751363_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003601 266.0
PYH1_k127_6751363_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000001349 244.0
PYH1_k127_6751363_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007982 238.0
PYH1_k127_6751363_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000005882 132.0
PYH1_k127_6751363_6 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000002005 119.0
PYH1_k127_6753493_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 297.0
PYH1_k127_6753493_1 - - - - 0.0000000000000000000000000000000086 135.0
PYH1_k127_6784543_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 356.0
PYH1_k127_6784543_1 Pkd domain containing protein - - - 0.0000000000000002147 94.0
PYH1_k127_6784543_2 CAAX protease self-immunity K07052 - - 0.00000001162 65.0
PYH1_k127_6837093_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000127 209.0
PYH1_k127_6837093_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000000002561 188.0
PYH1_k127_6837093_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000003788 172.0
PYH1_k127_6837093_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000001253 142.0
PYH1_k127_6844955_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 278.0
PYH1_k127_6844955_1 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000004567 150.0
PYH1_k127_6844955_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000001974 58.0
PYH1_k127_6861699_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002138 241.0
PYH1_k127_6861699_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000007825 169.0
PYH1_k127_6861699_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000001568 143.0
PYH1_k127_6871446_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 358.0
PYH1_k127_6871446_1 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 262.0
PYH1_k127_6871446_2 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000004018 183.0
PYH1_k127_6871446_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000006093 121.0
PYH1_k127_6871446_4 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000001536 102.0
PYH1_k127_6871446_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.0000000001708 67.0
PYH1_k127_6888987_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 513.0
PYH1_k127_6888987_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 326.0
PYH1_k127_6888987_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000009995 250.0
PYH1_k127_6888987_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000005925 183.0
PYH1_k127_6888987_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000008835 100.0
PYH1_k127_689492_0 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 317.0
PYH1_k127_689492_1 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008466 255.0
PYH1_k127_689492_2 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000001313 153.0
PYH1_k127_689492_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000003825 147.0
PYH1_k127_689492_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000003614 98.0
PYH1_k127_689492_7 phosphorelay sensor kinase activity - - - 0.0000000368 65.0
PYH1_k127_6905706_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 9.579e-295 912.0
PYH1_k127_6905706_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 9.352e-238 749.0
PYH1_k127_6905706_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 6.825e-204 648.0
PYH1_k127_6905706_3 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 556.0
PYH1_k127_6905706_4 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002568 252.0
PYH1_k127_6905706_5 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000009606 200.0
PYH1_k127_6905706_6 Protein of unknown function (DUF2934) - - - 0.00002515 51.0
PYH1_k127_6997091_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 323.0
PYH1_k127_6997091_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
PYH1_k127_6997091_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000001044 85.0
PYH1_k127_701448_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 426.0
PYH1_k127_701448_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000004405 220.0
PYH1_k127_701448_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000001191 177.0
PYH1_k127_7044951_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1184.0
PYH1_k127_7044951_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.103e-274 859.0
PYH1_k127_7044951_2 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 323.0
PYH1_k127_7044951_3 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006967 134.0
PYH1_k127_7068190_0 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 451.0
PYH1_k127_7068190_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 302.0
PYH1_k127_7068190_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003423 280.0
PYH1_k127_7068190_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 267.0
PYH1_k127_7068190_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000002041 237.0
PYH1_k127_7068190_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000001987 135.0
PYH1_k127_7068190_6 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000004905 96.0
PYH1_k127_7068190_7 Lipopolysaccharide-assembly, LptC-related - - - 0.0001595 51.0
PYH1_k127_7070655_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 413.0
PYH1_k127_7070655_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 387.0
PYH1_k127_7070655_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000007237 248.0
PYH1_k127_7070655_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000003435 163.0
PYH1_k127_7070655_4 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000004916 96.0
PYH1_k127_7070655_5 Alginate export - - - 0.00000004526 54.0
PYH1_k127_7089433_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 508.0
PYH1_k127_7089433_1 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 504.0
PYH1_k127_7089433_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000008907 148.0
PYH1_k127_7089433_3 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000002221 116.0
PYH1_k127_7089433_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000003779 53.0
PYH1_k127_7089433_5 RecX family K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0009972 48.0
PYH1_k127_7129727_0 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 354.0
PYH1_k127_7129727_1 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000833 195.0
PYH1_k127_7129727_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000637 162.0
PYH1_k127_7129727_3 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000001497 127.0
PYH1_k127_7129727_4 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000009045 106.0
PYH1_k127_7141936_0 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 342.0
PYH1_k127_7141936_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000001202 141.0
PYH1_k127_721479_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1464.0
PYH1_k127_721479_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 529.0
PYH1_k127_721479_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 378.0
PYH1_k127_721479_3 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000002111 219.0
PYH1_k127_7222550_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 577.0
PYH1_k127_7222550_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 554.0
PYH1_k127_7222550_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000006074 68.0
PYH1_k127_7235365_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 2.302e-242 761.0
PYH1_k127_7235365_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 458.0
PYH1_k127_7235365_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000002252 178.0
PYH1_k127_7245613_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002975 278.0
PYH1_k127_7245613_1 HypF finger K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000001113 244.0
PYH1_k127_7345710_0 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 409.0
PYH1_k127_7345710_1 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003253 231.0
PYH1_k127_7345710_2 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000006946 223.0
PYH1_k127_7345710_3 Transposase K07491 - - 0.00000000002511 64.0
PYH1_k127_7369282_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 349.0
PYH1_k127_7369282_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000001656 229.0
PYH1_k127_7369282_2 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000006521 115.0
PYH1_k127_7447551_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 445.0
PYH1_k127_7447551_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001445 238.0
PYH1_k127_7447551_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000002368 229.0
PYH1_k127_7447551_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000001933 79.0
PYH1_k127_7453812_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.15e-231 722.0
PYH1_k127_7453812_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 7.944e-204 644.0
PYH1_k127_7453812_2 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 555.0
PYH1_k127_7453812_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000001583 185.0
PYH1_k127_7453812_4 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000002335 131.0
PYH1_k127_7453812_5 Transcriptional regulator K02529 - - 0.00000000000000003185 91.0
PYH1_k127_7453812_6 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000001338 74.0
PYH1_k127_7456315_0 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000129 193.0
PYH1_k127_7456315_1 PAS fold - - - 0.0000000000000000000000000000000000000001502 162.0
PYH1_k127_7456315_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000002257 141.0
PYH1_k127_7456315_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000003305 115.0
PYH1_k127_7472721_0 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000004558 213.0
PYH1_k127_7472721_1 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000007646 142.0
PYH1_k127_7472721_2 deoxyhypusine monooxygenase activity - - - 0.000000000000000000005138 101.0
PYH1_k127_7472721_3 - - - - 0.00000000000002762 75.0
PYH1_k127_7472721_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000001984 66.0
PYH1_k127_7510465_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 578.0
PYH1_k127_7510465_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 527.0
PYH1_k127_7510465_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 269.0
PYH1_k127_7573819_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 410.0
PYH1_k127_7573819_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 378.0
PYH1_k127_7573819_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 318.0
PYH1_k127_7573819_3 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000002763 228.0
PYH1_k127_7573819_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000004564 90.0
PYH1_k127_7573819_5 Glycosyl hydrolase family 57 - - - 0.000000000000004009 80.0
PYH1_k127_7576728_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 364.0
PYH1_k127_7576728_1 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 286.0
PYH1_k127_7580928_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 297.0
PYH1_k127_7580928_1 - - - - 0.00000000000000000000005482 104.0
PYH1_k127_7606835_0 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 464.0
PYH1_k127_7606835_1 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000007038 225.0
PYH1_k127_7606835_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000001135 167.0
PYH1_k127_7606835_3 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000003531 94.0
PYH1_k127_7610450_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 5.786e-217 690.0
PYH1_k127_7610450_1 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 405.0
PYH1_k127_7610450_2 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000001842 109.0
PYH1_k127_7617416_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
PYH1_k127_7617416_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000003014 232.0
PYH1_k127_7621425_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 505.0
PYH1_k127_7621425_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 422.0
PYH1_k127_7621425_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 397.0
PYH1_k127_7621425_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000001783 222.0
PYH1_k127_7621425_4 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000005305 143.0
PYH1_k127_7625146_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 496.0
PYH1_k127_7625146_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 352.0
PYH1_k127_7625146_2 ADP-glucose pyrophosphohydrolase activity K00652,K01515,K13987 - 2.3.1.47,2.7.7.96,3.6.1.13,3.6.1.58 0.0000000000000001757 89.0
PYH1_k127_7625146_3 HIT domain K02503 - - 0.00000000000009099 71.0
PYH1_k127_7693052_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 479.0
PYH1_k127_7693052_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 344.0
PYH1_k127_7693052_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000001166 186.0
PYH1_k127_7693052_3 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000001486 148.0
PYH1_k127_7693052_4 cheY-homologous receiver domain - - - 0.00000000000000000000000006191 117.0
PYH1_k127_7693052_5 iron-sulfur cluster assembly - - - 0.000000000000000000001312 96.0
PYH1_k127_7693052_6 cobalt transport protein K16785 - - 0.000000128 61.0
PYH1_k127_7715599_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 3.657e-210 668.0
PYH1_k127_7715599_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004508 263.0
PYH1_k127_7715599_2 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000002002 220.0
PYH1_k127_7751845_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 548.0
PYH1_k127_7751845_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 329.0
PYH1_k127_7751845_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000002673 113.0
PYH1_k127_7761526_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 447.0
PYH1_k127_7761526_1 transposition K07497 - - 0.00000000000000000000000005355 109.0
PYH1_k127_7767886_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 497.0
PYH1_k127_7767886_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 369.0
PYH1_k127_7767886_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002362 260.0
PYH1_k127_7767886_3 - - - - 0.00000000000000000000000000000000000000000000000000000006536 209.0
PYH1_k127_7767886_4 Chemotaxis phosphatase CheX - - - 0.0000000000000000000000000000000000000000000000000001929 196.0
PYH1_k127_7767886_5 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000001051 147.0
PYH1_k127_7767886_6 Protein of unknown function DUF86 - - - 0.0000000000000000000000000003484 117.0
PYH1_k127_7767886_7 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000000000000000002148 106.0
PYH1_k127_7767886_8 ABC-2 type transporter K09694 - - 0.00002083 47.0
PYH1_k127_7808939_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 583.0
PYH1_k127_7808939_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 345.0
PYH1_k127_7808939_2 Glutaredoxin K03676 - - 0.00000000000009024 72.0
PYH1_k127_7846488_0 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 565.0
PYH1_k127_7846488_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 390.0
PYH1_k127_7846488_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 311.0
PYH1_k127_7846488_3 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000003474 55.0
PYH1_k127_7846488_4 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000004853 51.0
PYH1_k127_7846488_5 - - - - 0.0002677 44.0
PYH1_k127_785059_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 473.0
PYH1_k127_785059_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 373.0
PYH1_k127_785059_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 325.0
PYH1_k127_785059_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 263.0
PYH1_k127_785059_4 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000006794 208.0
PYH1_k127_785059_5 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.0000000000000000000000000000000000000001042 153.0
PYH1_k127_7875948_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.575e-273 856.0
PYH1_k127_7875948_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 302.0
PYH1_k127_7875948_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000001086 88.0
PYH1_k127_7902366_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 401.0
PYH1_k127_7902366_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 302.0
PYH1_k127_7902366_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000325 115.0
PYH1_k127_7902366_3 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000002882 89.0
PYH1_k127_792077_0 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 456.0
PYH1_k127_792077_1 - - - - 0.0000000000000000000000000000000000000000000133 166.0
PYH1_k127_792077_2 Cytochrome c K08906,K12263 - - 0.0000000000000000000001116 102.0
PYH1_k127_792077_3 Universal stress protein family K07090 - - 0.000000000000000000004543 99.0
PYH1_k127_792077_4 Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01886 - 6.1.1.18 0.000006587 48.0
PYH1_k127_7960543_0 Glycosyl hydrolase family 57 - - - 1.927e-209 669.0
PYH1_k127_7960543_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 444.0
PYH1_k127_7960543_2 - - - - 0.000000000000000000000000000003861 135.0
PYH1_k127_7960543_3 cell cycle K05589,K12065,K13052 - - 0.000000000000001907 80.0
PYH1_k127_8033736_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.729e-289 899.0
PYH1_k127_8033736_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 368.0
PYH1_k127_8033736_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 332.0
PYH1_k127_8033736_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 296.0
PYH1_k127_8033736_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000009603 82.0
PYH1_k127_8070037_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 583.0
PYH1_k127_8070037_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 450.0
PYH1_k127_8070037_10 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000005576 63.0
PYH1_k127_8070037_11 Membrane - - - 0.00000001887 58.0
PYH1_k127_8070037_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 322.0
PYH1_k127_8070037_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007748 281.0
PYH1_k127_8070037_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000232 265.0
PYH1_k127_8070037_5 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000008441 235.0
PYH1_k127_8070037_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000003733 206.0
PYH1_k127_8070037_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000002664 123.0
PYH1_k127_8070037_9 RNA recognition motif - - - 0.000000000000000000000000002347 115.0
PYH1_k127_8098786_0 heat shock protein binding - - - 0.0000000000000000000000000000000000007707 150.0
PYH1_k127_8098786_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000004927 93.0
PYH1_k127_8172244_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 362.0
PYH1_k127_8172244_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 306.0
PYH1_k127_8172244_2 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.00000000000000000000000000000000002296 144.0
PYH1_k127_8172244_3 auxin-activated signaling pathway K07088 - - 0.00000000002488 66.0
PYH1_k127_8183679_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 364.0
PYH1_k127_8183679_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 353.0
PYH1_k127_8183679_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 338.0
PYH1_k127_8183679_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
PYH1_k127_8183679_4 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000004392 221.0
PYH1_k127_8183679_5 EamA-like transporter family - - - 0.000000000000679 76.0
PYH1_k127_8204309_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000009124 163.0
PYH1_k127_8204309_1 Crp Fnr family transcriptional regulator - - - 0.0000000504 63.0
PYH1_k127_8212132_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 478.0
PYH1_k127_8212132_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 351.0
PYH1_k127_828607_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 1.584e-247 774.0
PYH1_k127_828607_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 550.0
PYH1_k127_828607_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 415.0
PYH1_k127_8365462_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 342.0
PYH1_k127_8365462_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 311.0
PYH1_k127_8365462_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
PYH1_k127_8365462_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 290.0
PYH1_k127_8365462_4 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000001704 163.0
PYH1_k127_8365462_5 PBS lyase HEAT-like repeat - - - 0.0000000001016 70.0
PYH1_k127_85567_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 428.0
PYH1_k127_85567_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000911 126.0
PYH1_k127_888825_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 339.0
PYH1_k127_888825_1 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001044 225.0
PYH1_k127_888825_2 - - - - 0.000000000000000000001893 102.0
PYH1_k127_888825_3 - - - - 0.00000000000000006195 90.0
PYH1_k127_890181_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.402e-303 949.0
PYH1_k127_890181_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 532.0
PYH1_k127_890181_2 SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 327.0
PYH1_k127_890181_3 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000004608 197.0
PYH1_k127_890181_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00004633 46.0
PYH1_k127_890181_5 - - - - 0.00006738 54.0
PYH1_k127_89523_0 Heat shock 70 kDa protein K04043 - - 2.66e-275 851.0
PYH1_k127_89523_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 448.0
PYH1_k127_89523_2 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 420.0
PYH1_k127_89523_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 310.0
PYH1_k127_89523_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000002667 156.0
PYH1_k127_92408_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 419.0
PYH1_k127_92408_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 347.0
PYH1_k127_92408_2 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000001495 241.0
PYH1_k127_92408_3 - - - - 0.000000000000009681 82.0
PYH1_k127_942438_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 417.0
PYH1_k127_942438_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002047 248.0
PYH1_k127_942438_2 DEAD DEAH box helicase domain protein K06877 - - 0.00000003256 57.0
PYH1_k127_944500_0 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 394.0
PYH1_k127_944500_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
PYH1_k127_944500_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 372.0
PYH1_k127_944500_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000002477 171.0
PYH1_k127_944500_4 Sulfurtransferase TusA - - - 0.0000000000000000000174 93.0
PYH1_k127_944500_5 - - - - 0.000000000000002515 83.0
PYH1_k127_946721_0 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000952 102.0
PYH1_k127_946721_1 peptidyl-tyrosine sulfation - - - 0.0000009548 61.0
PYH1_k127_948034_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 296.0
PYH1_k127_948034_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 283.0
PYH1_k127_948034_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000007956 111.0
PYH1_k127_961847_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 514.0
PYH1_k127_961847_1 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 428.0
PYH1_k127_961847_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 307.0
PYH1_k127_961847_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000001511 197.0
PYH1_k127_961847_4 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000005697 156.0
PYH1_k127_961852_0 FMN binding - - - 9.972e-276 854.0
PYH1_k127_961852_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 589.0
PYH1_k127_961852_10 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000001768 104.0
PYH1_k127_961852_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 501.0
PYH1_k127_961852_3 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 421.0
PYH1_k127_961852_4 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 404.0
PYH1_k127_961852_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 338.0
PYH1_k127_961852_6 PFAM ferredoxin-dependent glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 314.0
PYH1_k127_961852_7 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000001403 202.0
PYH1_k127_961852_8 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000008341 182.0
PYH1_k127_961852_9 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000001977 117.0
PYH1_k127_978607_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 561.0
PYH1_k127_978607_1 FAD binding domain K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000009735 261.0
PYH1_k127_978607_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000007608 252.0
PYH1_k127_98493_0 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005323 255.0
PYH1_k127_98493_1 Transcriptional regulator - - - 0.00000000000000000000001664 103.0
PYH1_k127_98493_2 Tetratricopeptide repeat-like domain - - - 0.0000000000003874 78.0
PYH1_k127_991021_0 ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 449.0
PYH1_k127_991021_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000024 85.0