Overview

ID MAG03135
Name PYH1_bin.25
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class UBA9217
Order UBA9217
Family UBA9217
Genus JAAXXJ01
Species
Assembly information
Completeness (%) 68.94
Contamination (%) 1.59
GC content (%) 60.0
N50 (bp) 5,918
Genome size (bp) 1,839,609

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1897

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1023250_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.963e-201 639.0
PYH1_k127_1023250_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000004669 231.0
PYH1_k127_1023250_2 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000008241 188.0
PYH1_k127_1023250_3 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000002392 154.0
PYH1_k127_1023250_4 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000009116 117.0
PYH1_k127_1023250_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000004565 108.0
PYH1_k127_1023250_6 Domain of unknown function (DUF4253) - - - 0.00000000000008114 81.0
PYH1_k127_1023660_0 family UPF0324 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 428.0
PYH1_k127_1023660_1 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000114 273.0
PYH1_k127_1023660_2 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000006134 227.0
PYH1_k127_1023660_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000005969 114.0
PYH1_k127_1023660_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000001046 124.0
PYH1_k127_1023660_5 Methylamine utilisation protein MauE - - - 0.0000000000000000003807 94.0
PYH1_k127_1028464_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 411.0
PYH1_k127_1028464_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000007596 166.0
PYH1_k127_1028464_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000003718 108.0
PYH1_k127_1030721_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 490.0
PYH1_k127_1030721_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 323.0
PYH1_k127_1030721_2 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000118 224.0
PYH1_k127_1030721_3 cytochrome - - - 0.0000000000000000000001146 104.0
PYH1_k127_1030721_4 Serine Threonine protein kinase K08738 - - 0.000000000005759 78.0
PYH1_k127_1030721_5 Belongs to the HesB IscA family K13628 - - 0.00000000001988 70.0
PYH1_k127_1031032_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 497.0
PYH1_k127_1031032_1 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 306.0
PYH1_k127_1031032_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 301.0
PYH1_k127_1031032_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005051 271.0
PYH1_k127_1031032_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000001103 197.0
PYH1_k127_1031032_5 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000000118 161.0
PYH1_k127_1031032_6 Roadblock/LC7 domain - - - 0.0000000000000000000000005583 111.0
PYH1_k127_1031032_7 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.0000000000000002877 92.0
PYH1_k127_1051864_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 474.0
PYH1_k127_1051864_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 471.0
PYH1_k127_1051864_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000001879 233.0
PYH1_k127_1051864_3 Belongs to the DsbB family K03611 - - 0.0000000000000000000000000000000000000000000007399 169.0
PYH1_k127_1054684_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 479.0
PYH1_k127_1054684_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 296.0
PYH1_k127_1054684_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000002891 75.0
PYH1_k127_1054684_11 Cupin 2, conserved barrel domain protein - - - 0.0000000003357 66.0
PYH1_k127_1054684_2 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000008892 238.0
PYH1_k127_1054684_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
PYH1_k127_1054684_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000003886 199.0
PYH1_k127_1054684_5 Hemerythrin HHE cation binding K07322 - - 0.0000000000000000000000000000000000003434 145.0
PYH1_k127_1054684_6 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000001276 134.0
PYH1_k127_1054684_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000000009155 142.0
PYH1_k127_1054684_8 PFAM CBS domain - - - 0.0000000000000000000000000001041 123.0
PYH1_k127_1054684_9 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000000006639 96.0
PYH1_k127_1069283_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 417.0
PYH1_k127_1069283_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 299.0
PYH1_k127_1069283_2 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000001931 156.0
PYH1_k127_1069283_3 cobalamin synthesis protein, P47K - - - 0.0000000000000000000000000000000000000002615 161.0
PYH1_k127_1069283_4 Tetratricopeptide repeat - - - 0.000000000000000000000000001258 120.0
PYH1_k127_1069283_5 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.00000003307 55.0
PYH1_k127_1069283_6 cheY-homologous receiver domain - - - 0.0003415 49.0
PYH1_k127_1092391_0 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003281 260.0
PYH1_k127_1092391_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000009197 261.0
PYH1_k127_1092391_2 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
PYH1_k127_1092391_3 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000004584 193.0
PYH1_k127_1092391_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000004875 176.0
PYH1_k127_11163_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 492.0
PYH1_k127_11163_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 459.0
PYH1_k127_11163_2 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 331.0
PYH1_k127_11163_3 Belongs to the MraZ family K03925 - - 0.00000000000000000001223 93.0
PYH1_k127_11163_4 antisigma factor binding - - - 0.0000000229 60.0
PYH1_k127_11163_5 Cell division protein FtsL - - - 0.0002024 51.0
PYH1_k127_1127699_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 423.0
PYH1_k127_1127699_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 376.0
PYH1_k127_1127699_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000007814 146.0
PYH1_k127_1146062_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 339.0
PYH1_k127_1146062_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000005654 138.0
PYH1_k127_1217181_0 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 2.67e-219 709.0
PYH1_k127_1217181_1 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 425.0
PYH1_k127_1217181_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 414.0
PYH1_k127_1217181_3 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000727 213.0
PYH1_k127_1217181_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000002183 178.0
PYH1_k127_1217181_5 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.000000000000000000000000006179 111.0
PYH1_k127_1217181_7 Histidine kinase - - - 0.00000001092 58.0
PYH1_k127_122715_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 294.0
PYH1_k127_122715_1 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002026 261.0
PYH1_k127_122715_2 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000003337 231.0
PYH1_k127_122715_3 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000000000000000000000000000001321 230.0
PYH1_k127_1227528_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 523.0
PYH1_k127_1227528_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 482.0
PYH1_k127_1227528_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000449 241.0
PYH1_k127_1227528_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000006194 161.0
PYH1_k127_1227528_4 PFAM response regulator receiver - - - 0.0000000000000000000000000000000799 127.0
PYH1_k127_1228642_0 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
PYH1_k127_1228642_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 263.0
PYH1_k127_1228642_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 256.0
PYH1_k127_1228642_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000004383 225.0
PYH1_k127_1228642_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
PYH1_k127_1228642_5 Long-chain acyl-CoA synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000237 136.0
PYH1_k127_1228642_7 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000465 128.0
PYH1_k127_1228642_8 - - - - 0.000000000000000002558 93.0
PYH1_k127_1228642_9 PFAM amino acid-binding ACT domain protein - - - 0.0000003125 60.0
PYH1_k127_1241568_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 486.0
PYH1_k127_1241568_1 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003597 262.0
PYH1_k127_1241568_2 HNH nucleases - - - 0.00000000000000000000000000000000000000001265 156.0
PYH1_k127_1241568_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000699 145.0
PYH1_k127_1244317_0 TPR repeat - - - 7.868e-294 925.0
PYH1_k127_1244317_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 568.0
PYH1_k127_1244317_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 414.0
PYH1_k127_1244317_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 370.0
PYH1_k127_1244317_4 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001569 249.0
PYH1_k127_1244317_5 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002413 227.0
PYH1_k127_1244317_6 polysaccharide deacetylase K11931,K21478 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016787,GO:0016810,GO:0043170,GO:0043412,GO:0071704,GO:0098732 - 0.0000000000000000000000000000000000000000000000000002631 199.0
PYH1_k127_1244317_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000228 169.0
PYH1_k127_1252259_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1104.0
PYH1_k127_1252259_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
PYH1_k127_1252259_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 306.0
PYH1_k127_1252259_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001888 284.0
PYH1_k127_1252259_4 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000006464 144.0
PYH1_k127_1252259_5 PFAM response regulator receiver - - - 0.000000000000000000000000000000002957 132.0
PYH1_k127_1252259_6 cheY-homologous receiver domain - - - 0.000000000000000000000000001639 127.0
PYH1_k127_1270208_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 585.0
PYH1_k127_1270208_1 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000001183 150.0
PYH1_k127_1270208_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000003587 68.0
PYH1_k127_1290350_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
PYH1_k127_1290350_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000008246 269.0
PYH1_k127_1290350_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000002685 166.0
PYH1_k127_1290350_3 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000001889 123.0
PYH1_k127_1290350_4 Regulatory protein, FmdB family - - - 0.000000000000000002092 90.0
PYH1_k127_1290350_5 domain protein - - - 0.00002489 53.0
PYH1_k127_1290350_6 PilZ domain - - - 0.0002609 48.0
PYH1_k127_1290350_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0003215 45.0
PYH1_k127_1329789_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 545.0
PYH1_k127_1329789_1 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 308.0
PYH1_k127_1329789_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
PYH1_k127_1329789_3 response regulator receiver - - - 0.000000000000000000000000000000000000000000003712 168.0
PYH1_k127_1329789_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000001235 123.0
PYH1_k127_1329789_5 DsrE/DsrF-like family - - - 0.0000002415 57.0
PYH1_k127_143291_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.059e-210 673.0
PYH1_k127_143291_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 312.0
PYH1_k127_143291_2 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000006934 250.0
PYH1_k127_143291_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000107 113.0
PYH1_k127_143291_4 TIGRFAM regulatory protein, FmdB - - - 0.00000000004079 67.0
PYH1_k127_1541611_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 527.0
PYH1_k127_1541611_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 480.0
PYH1_k127_1541611_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 398.0
PYH1_k127_1541611_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 327.0
PYH1_k127_1541611_4 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001142 285.0
PYH1_k127_1541611_5 Domain of unknown function (DUF1844) - - - 0.0000000000000000000243 98.0
PYH1_k127_1541611_6 CbiX K03794,K03795 - 4.99.1.3,4.99.1.4 0.000000000000005528 82.0
PYH1_k127_157237_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 414.0
PYH1_k127_157237_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 373.0
PYH1_k127_157237_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002469 194.0
PYH1_k127_157237_3 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000276 173.0
PYH1_k127_157237_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000001647 166.0
PYH1_k127_157237_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000001424 147.0
PYH1_k127_157237_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000002992 79.0
PYH1_k127_1576467_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 255.0
PYH1_k127_1576467_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008138 199.0
PYH1_k127_1576467_2 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000006673 124.0
PYH1_k127_1576467_3 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000008876 117.0
PYH1_k127_1576467_4 Ribosomal L29 protein K02904 - - 0.000000000000006837 76.0
PYH1_k127_166285_0 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 547.0
PYH1_k127_166285_1 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 370.0
PYH1_k127_166285_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000009524 138.0
PYH1_k127_1693287_0 phosphate binding protein K02040 - - 0.0000000000000000000000002204 115.0
PYH1_k127_1693287_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00006063 54.0
PYH1_k127_1705360_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 499.0
PYH1_k127_1705360_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 409.0
PYH1_k127_1705360_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 358.0
PYH1_k127_1705360_3 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 329.0
PYH1_k127_1705360_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
PYH1_k127_1705360_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003053 267.0
PYH1_k127_1705360_6 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000005277 181.0
PYH1_k127_1705360_7 - - - - 0.000000000000001512 82.0
PYH1_k127_1705360_8 small metal-binding protein - - - 0.00007738 50.0
PYH1_k127_1780178_0 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 493.0
PYH1_k127_1780178_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 0.0000000000000000000000000000000000001096 145.0
PYH1_k127_1780178_3 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000006877 57.0
PYH1_k127_1780588_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.367e-197 623.0
PYH1_k127_1780588_1 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000098 250.0
PYH1_k127_1780588_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000002802 134.0
PYH1_k127_1786344_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 350.0
PYH1_k127_1786344_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
PYH1_k127_1786344_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000155 193.0
PYH1_k127_1786344_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000003485 123.0
PYH1_k127_1786344_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000000001839 84.0
PYH1_k127_1800839_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1185.0
PYH1_k127_1800839_1 Alpha/beta hydrolase family K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 411.0
PYH1_k127_1800839_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 304.0
PYH1_k127_1800839_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001079 273.0
PYH1_k127_1800839_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000001448 201.0
PYH1_k127_1800839_5 Cysteine-rich small domain K07162 - - 0.00000000000000000000001273 103.0
PYH1_k127_1800839_6 Alcohol dehydrogenase - - - 0.0000000000000266 73.0
PYH1_k127_1805683_0 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 381.0
PYH1_k127_1805683_1 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000926 274.0
PYH1_k127_1805683_2 Tetratricopeptide repeat - - - 0.000000007847 58.0
PYH1_k127_1812462_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.243e-208 659.0
PYH1_k127_1812462_1 elongation factor G domain IV K02355 - - 1.582e-207 667.0
PYH1_k127_1812462_2 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 569.0
PYH1_k127_1812462_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 516.0
PYH1_k127_1812462_4 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 410.0
PYH1_k127_1812462_5 NIL - - - 0.000000000000000000000005603 103.0
PYH1_k127_1812462_6 - - - - 0.000000000000000000008151 95.0
PYH1_k127_1812462_7 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000001528 72.0
PYH1_k127_1816607_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 346.0
PYH1_k127_1816607_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000005249 193.0
PYH1_k127_1816607_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000006675 149.0
PYH1_k127_1816607_3 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000003117 109.0
PYH1_k127_1816607_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000007305 98.0
PYH1_k127_1830769_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 433.0
PYH1_k127_1830769_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
PYH1_k127_1830769_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000004569 206.0
PYH1_k127_1830769_3 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000005034 208.0
PYH1_k127_1830769_4 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000156 124.0
PYH1_k127_1830769_5 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000004871 116.0
PYH1_k127_1830769_6 - - - - 0.000000000000000000003969 98.0
PYH1_k127_1830769_7 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000007206 89.0
PYH1_k127_1830769_8 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000001231 61.0
PYH1_k127_1836133_0 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 359.0
PYH1_k127_1836133_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 308.0
PYH1_k127_1836133_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000003277 139.0
PYH1_k127_1836133_4 TonB C terminal K03832 - - 0.00000005286 63.0
PYH1_k127_1836167_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 5.782e-240 758.0
PYH1_k127_1836167_1 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 348.0
PYH1_k127_1836167_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 319.0
PYH1_k127_1836167_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000765 209.0
PYH1_k127_1836167_4 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000003773 168.0
PYH1_k127_1836167_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000006419 163.0
PYH1_k127_1836167_6 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000004619 108.0
PYH1_k127_1836167_7 - - - - 0.00000000000000003315 85.0
PYH1_k127_1843077_0 ATP-dependent helicase K03579 - 3.6.4.13 1.408e-195 633.0
PYH1_k127_1843077_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000003298 75.0
PYH1_k127_185189_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 391.0
PYH1_k127_185189_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005802 250.0
PYH1_k127_185189_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000001313 209.0
PYH1_k127_185189_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001687 157.0
PYH1_k127_185189_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002156 126.0
PYH1_k127_185189_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000005323 116.0
PYH1_k127_185189_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000009402 114.0
PYH1_k127_1858717_0 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 357.0
PYH1_k127_1858717_1 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000009216 200.0
PYH1_k127_1858717_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000001815 164.0
PYH1_k127_1858717_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000003221 124.0
PYH1_k127_1858717_4 Domain of unknown function (DUF1858) - - - 0.000000000000000003478 86.0
PYH1_k127_1858717_5 - - - - 0.00000000000000003421 87.0
PYH1_k127_1858717_6 - - - - 0.0000008931 52.0
PYH1_k127_1871354_0 protein histidine kinase activity K02491,K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000003865 180.0
PYH1_k127_1871354_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000002564 156.0
PYH1_k127_1871354_2 Tetratricopeptide repeat protein - - - 0.0000002981 59.0
PYH1_k127_1897384_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 6.004e-248 780.0
PYH1_k127_1897384_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 322.0
PYH1_k127_1897384_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000001185 83.0
PYH1_k127_1904367_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 244.0
PYH1_k127_1904367_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000001508 235.0
PYH1_k127_1904367_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000248 127.0
PYH1_k127_1904367_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0003502 49.0
PYH1_k127_1945361_1 Copper chaperone PCu(A)C K09796 - - 0.0000000000000001752 85.0
PYH1_k127_1945361_2 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000002351 68.0
PYH1_k127_2006144_0 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 1.195e-251 786.0
PYH1_k127_2006144_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000005359 203.0
PYH1_k127_2006144_2 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000000000000000000001745 151.0
PYH1_k127_2006144_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.000000000000000000000000000000000007249 140.0
PYH1_k127_2033822_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 309.0
PYH1_k127_2033822_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000006904 213.0
PYH1_k127_2033822_2 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000005601 151.0
PYH1_k127_2055061_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 260.0
PYH1_k127_2055061_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
PYH1_k127_2055061_2 NHL repeat - - - 0.0000000000000000000005658 108.0
PYH1_k127_2079931_0 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 426.0
PYH1_k127_2079931_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000004706 207.0
PYH1_k127_2079931_2 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000001328 192.0
PYH1_k127_2079931_3 EAL domain K20963 - 3.1.4.52 0.000000000000000000000000000000001596 139.0
PYH1_k127_2079931_4 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000001123 131.0
PYH1_k127_2079931_5 PFAM response regulator receiver - - - 0.00000000003844 70.0
PYH1_k127_2103253_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006637 252.0
PYH1_k127_2103253_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000003155 216.0
PYH1_k127_2108879_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 490.0
PYH1_k127_2108879_1 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 359.0
PYH1_k127_2108879_10 Protein of unknown function (DUF3185) - - - 0.00008068 48.0
PYH1_k127_2108879_11 cellulase activity - - - 0.00009437 51.0
PYH1_k127_2108879_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 342.0
PYH1_k127_2108879_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 327.0
PYH1_k127_2108879_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
PYH1_k127_2108879_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006488 279.0
PYH1_k127_2108879_6 channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 261.0
PYH1_k127_2108879_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000008242 186.0
PYH1_k127_2108879_9 chemotaxis protein K03406 - - 0.0000005986 58.0
PYH1_k127_2125916_0 Pyruvate kinase, alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 402.0
PYH1_k127_2125916_1 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000634 209.0
PYH1_k127_2125916_2 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000005596 204.0
PYH1_k127_2125916_3 - - - - 0.0000000000008271 77.0
PYH1_k127_2125916_4 cheY-homologous receiver domain - - - 0.0000000005399 66.0
PYH1_k127_2125916_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000008603 63.0
PYH1_k127_2147139_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 7.86e-209 653.0
PYH1_k127_2147139_1 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000002692 121.0
PYH1_k127_2147139_2 Domain of unknown function (DUF4416) - - - 0.00000000000000441 78.0
PYH1_k127_2147139_3 domain protein K20276 - - 0.000000004905 67.0
PYH1_k127_2147139_4 LPP20 lipoprotein - - - 0.0000001163 63.0
PYH1_k127_2154143_0 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000009466 233.0
PYH1_k127_2154143_1 SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000000000000000000005346 207.0
PYH1_k127_2154143_2 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000005919 207.0
PYH1_k127_2154143_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000001728 190.0
PYH1_k127_2154143_4 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.000000000000000536 83.0
PYH1_k127_2154143_5 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000006461 83.0
PYH1_k127_2161797_0 DNA polymerase A domain K02335 - 2.7.7.7 3.332e-302 951.0
PYH1_k127_2161797_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000001254 239.0
PYH1_k127_2161797_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000001459 233.0
PYH1_k127_2161797_3 PFAM Late competence development protein ComFB K02241 - - 0.00000005592 58.0
PYH1_k127_2161797_4 PFAM NHL repeat containing protein - - - 0.000003837 53.0
PYH1_k127_217748_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.966e-202 644.0
PYH1_k127_217748_1 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000001573 200.0
PYH1_k127_2246627_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000006679 204.0
PYH1_k127_2246627_1 YHS domain protein - - - 0.000000000000000000000000000000000000000000000000000003005 196.0
PYH1_k127_2246627_2 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000000000002762 173.0
PYH1_k127_2246627_3 - - - - 0.000004673 49.0
PYH1_k127_233818_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 582.0
PYH1_k127_233818_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 477.0
PYH1_k127_233818_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
PYH1_k127_233818_11 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000004437 194.0
PYH1_k127_233818_12 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000002863 170.0
PYH1_k127_233818_13 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000009786 145.0
PYH1_k127_233818_14 - - - - 0.00000000000000000000000004013 119.0
PYH1_k127_233818_15 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000004533 79.0
PYH1_k127_233818_17 peptidyl-tyrosine sulfation - - - 0.000000000009607 72.0
PYH1_k127_233818_18 Domain of unknown function (DUF3786) - - - 0.0000000004924 68.0
PYH1_k127_233818_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 423.0
PYH1_k127_233818_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 376.0
PYH1_k127_233818_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
PYH1_k127_233818_5 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 301.0
PYH1_k127_233818_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 305.0
PYH1_k127_233818_7 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002772 288.0
PYH1_k127_233818_8 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
PYH1_k127_233818_9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000003058 258.0
PYH1_k127_2338651_0 CoA-substrate-specific enzyme activase - - - 4.37e-203 656.0
PYH1_k127_2338651_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 342.0
PYH1_k127_2457153_0 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000007353 227.0
PYH1_k127_2457153_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000004969 123.0
PYH1_k127_2457153_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00004346 49.0
PYH1_k127_2467268_0 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 380.0
PYH1_k127_2467268_1 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 373.0
PYH1_k127_2467268_2 HlyD family secretion protein K02005 - - 0.000000000009222 65.0
PYH1_k127_249124_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 533.0
PYH1_k127_249124_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000003525 220.0
PYH1_k127_249124_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000008656 187.0
PYH1_k127_249124_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000001513 190.0
PYH1_k127_249124_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000003074 126.0
PYH1_k127_249124_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000005988 125.0
PYH1_k127_2533758_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008727 263.0
PYH1_k127_2533758_1 - - - - 0.000000000000000000007447 105.0
PYH1_k127_254322_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 524.0
PYH1_k127_254322_1 PFAM Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000002926 151.0
PYH1_k127_254322_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000002212 130.0
PYH1_k127_254322_3 Tetratricopeptide repeat - - - 0.0000000000000000000000001232 113.0
PYH1_k127_254322_4 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000001255 55.0
PYH1_k127_2557430_0 Putative diguanylate phosphodiesterase - - - 2.71e-197 643.0
PYH1_k127_2557430_1 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 311.0
PYH1_k127_2557430_2 response regulator K07814 - - 0.000000000004783 75.0
PYH1_k127_2557430_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000001238 74.0
PYH1_k127_2569448_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 3.033e-239 753.0
PYH1_k127_2569448_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
PYH1_k127_2569448_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000624 235.0
PYH1_k127_2569448_3 PFAM FMN-binding domain - - - 0.0000000000000000000000000000000001434 149.0
PYH1_k127_2569448_4 Tetratricopeptide repeat - - - 0.000000555 61.0
PYH1_k127_2585286_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 582.0
PYH1_k127_2585286_1 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 307.0
PYH1_k127_2585286_10 general secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00006739 53.0
PYH1_k127_2585286_11 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0008791 47.0
PYH1_k127_2585286_2 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000001817 181.0
PYH1_k127_2585286_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000005219 91.0
PYH1_k127_2585286_4 Type IV pilus assembly protein PilM; K02461 - - 0.000000000000006183 88.0
PYH1_k127_2585286_5 Outer membrane protease K08566 - 3.4.23.48 0.00000000004215 74.0
PYH1_k127_2585286_6 - - - - 0.00000001973 62.0
PYH1_k127_2585286_7 Type II secretion system (T2SS), protein K K02460 - - 0.000005014 58.0
PYH1_k127_2585286_8 - - - - 0.000009277 57.0
PYH1_k127_2585286_9 Prokaryotic N-terminal methylation motif K02457 - - 0.00001895 55.0
PYH1_k127_2596822_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 362.0
PYH1_k127_2596822_1 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 295.0
PYH1_k127_2596822_2 - - - - 0.0003874 48.0
PYH1_k127_2599780_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 529.0
PYH1_k127_2599780_1 membrane - - - 0.00000000000000000000000000000001883 141.0
PYH1_k127_2599780_2 acid phosphatase activity K03651 - 3.1.4.53 0.0000000000000000000000000006627 125.0
PYH1_k127_2599780_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000009189 52.0
PYH1_k127_2639883_0 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 309.0
PYH1_k127_2639883_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000001868 212.0
PYH1_k127_2639883_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000418 101.0
PYH1_k127_2671912_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 6.574e-234 743.0
PYH1_k127_2671912_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 409.0
PYH1_k127_2671912_2 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000107 246.0
PYH1_k127_2671912_3 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000494 235.0
PYH1_k127_2671912_4 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000002157 153.0
PYH1_k127_2671912_5 chemotaxis sensory transducer K03406,K05874 - - 0.0000000000000000000002045 105.0
PYH1_k127_2671912_6 STAS domain - - - 0.00000000001059 70.0
PYH1_k127_2671912_7 Universal stress protein family - - - 0.000002384 55.0
PYH1_k127_2679492_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003717 286.0
PYH1_k127_2679492_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000004406 142.0
PYH1_k127_2679492_2 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000001849 115.0
PYH1_k127_2679492_3 PFAM Glutaredoxin K06191 - - 0.000000000000000000007325 99.0
PYH1_k127_2679492_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000001094 94.0
PYH1_k127_2686913_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
PYH1_k127_2686913_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000005952 222.0
PYH1_k127_2697266_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 338.0
PYH1_k127_2697266_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000008597 181.0
PYH1_k127_2697266_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000001649 121.0
PYH1_k127_2722530_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.617e-252 792.0
PYH1_k127_2722530_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001013 244.0
PYH1_k127_2722530_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000007377 145.0
PYH1_k127_2722530_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000001024 117.0
PYH1_k127_2722716_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 484.0
PYH1_k127_2722716_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 254.0
PYH1_k127_2722716_2 Peptidase S24-like K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000001233 202.0
PYH1_k127_2722716_3 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000008496 194.0
PYH1_k127_2722716_4 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000001171 174.0
PYH1_k127_2745970_0 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 374.0
PYH1_k127_2745970_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 250.0
PYH1_k127_2745970_2 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000003275 106.0
PYH1_k127_2745970_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000255 79.0
PYH1_k127_2765751_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 449.0
PYH1_k127_2765751_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 348.0
PYH1_k127_2765751_2 - - - - 0.0000000001046 63.0
PYH1_k127_2800305_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1523.0
PYH1_k127_2800305_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 548.0
PYH1_k127_2800305_10 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000001339 196.0
PYH1_k127_2800305_11 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000002862 183.0
PYH1_k127_2800305_12 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000001343 173.0
PYH1_k127_2800305_13 PFAM OmpA family K02557 - - 0.0000000000000000000000000000000001294 141.0
PYH1_k127_2800305_14 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000007672 87.0
PYH1_k127_2800305_15 Tetratricopeptide repeat K04734,K09553,K16362 GO:0000003,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006950,GO:0007275,GO:0007568,GO:0008022,GO:0008150,GO:0008340,GO:0009266,GO:0009408,GO:0009628,GO:0010259,GO:0012505,GO:0030234,GO:0030544,GO:0031072,GO:0032501,GO:0032502,GO:0032780,GO:0032991,GO:0042030,GO:0043086,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0048856,GO:0050790,GO:0050896,GO:0051087,GO:0051336,GO:0051346,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772,GO:0101031 - 0.00000703 58.0
PYH1_k127_2800305_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 546.0
PYH1_k127_2800305_3 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
PYH1_k127_2800305_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 394.0
PYH1_k127_2800305_5 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 346.0
PYH1_k127_2800305_6 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 353.0
PYH1_k127_2800305_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004838 275.0
PYH1_k127_2800305_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001995 277.0
PYH1_k127_2800305_9 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009425 251.0
PYH1_k127_2809396_0 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000233 292.0
PYH1_k127_2809396_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000139 90.0
PYH1_k127_284880_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000009004 256.0
PYH1_k127_284880_1 - - - - 0.000000000000000000000000000000000000104 147.0
PYH1_k127_284880_2 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000002566 125.0
PYH1_k127_288719_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 538.0
PYH1_k127_288719_1 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
PYH1_k127_288719_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 381.0
PYH1_k127_288719_3 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008304 274.0
PYH1_k127_288719_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001534 226.0
PYH1_k127_288719_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000006138 179.0
PYH1_k127_288719_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000007411 177.0
PYH1_k127_288719_7 methyltransferase - - - 0.000000000000000000000000000000000000001334 154.0
PYH1_k127_288719_8 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000007806 137.0
PYH1_k127_288719_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000133 119.0
PYH1_k127_296958_0 PFAM Transketolase K00615 - 2.2.1.1 1.024e-239 755.0
PYH1_k127_296958_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 328.0
PYH1_k127_296958_2 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 287.0
PYH1_k127_296958_3 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000007088 108.0
PYH1_k127_2970693_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 508.0
PYH1_k127_2970693_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000004242 140.0
PYH1_k127_2970693_2 PFAM Cyclic nucleotide-binding - - - 0.0000000000000001333 83.0
PYH1_k127_2981888_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 458.0
PYH1_k127_2981888_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 378.0
PYH1_k127_2981888_2 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000001777 134.0
PYH1_k127_2981888_3 Thioredoxin domain - - - 0.00000000000000000208 95.0
PYH1_k127_2981888_4 Cytochrome c7 and related cytochrome c - - - 0.000000387 56.0
PYH1_k127_2990170_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 361.0
PYH1_k127_2990170_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
PYH1_k127_2990170_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000001035 88.0
PYH1_k127_2990170_3 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000003868 70.0
PYH1_k127_2995488_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 553.0
PYH1_k127_2995488_1 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 256.0
PYH1_k127_2995488_2 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000005982 169.0
PYH1_k127_2995488_3 Crp-like helix-turn-helix domain K10914 - - 0.0000000000000000000000000000000000000000003704 166.0
PYH1_k127_2995488_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000003731 164.0
PYH1_k127_2995488_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000002345 120.0
PYH1_k127_2995488_6 Thiamine-binding protein - - - 0.000000000000000000000000002073 116.0
PYH1_k127_2995488_7 HNH nucleases - - - 0.0000000004846 59.0
PYH1_k127_3007159_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 8.955e-244 783.0
PYH1_k127_3007159_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000003473 207.0
PYH1_k127_3007159_2 FixH - - - 0.0000000000000007035 81.0
PYH1_k127_3007159_3 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000001266 85.0
PYH1_k127_3007159_4 membrane K12340 - - 0.00000000000007208 83.0
PYH1_k127_3007159_5 Cytochrome oxidase maturation protein - - - 0.000000000001202 73.0
PYH1_k127_304555_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 437.0
PYH1_k127_304555_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 358.0
PYH1_k127_304555_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001077 274.0
PYH1_k127_304555_3 Universal stress protein family - - - 0.000000003394 63.0
PYH1_k127_3092782_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 344.0
PYH1_k127_3092782_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
PYH1_k127_3092782_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000005363 172.0
PYH1_k127_3092782_3 Bacterial PH domain - - - 0.00004962 53.0
PYH1_k127_3172726_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 449.0
PYH1_k127_3172726_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 417.0
PYH1_k127_3172726_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 373.0
PYH1_k127_3172726_3 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000001126 148.0
PYH1_k127_3195927_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.508e-275 857.0
PYH1_k127_3195927_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008321 256.0
PYH1_k127_3195927_2 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003671 244.0
PYH1_k127_3195927_3 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000002067 220.0
PYH1_k127_3195927_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000001555 217.0
PYH1_k127_3195927_5 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002459 216.0
PYH1_k127_3195927_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000007733 166.0
PYH1_k127_3195927_7 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000208 105.0
PYH1_k127_3195927_8 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000002329 101.0
PYH1_k127_3195927_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000001513 61.0
PYH1_k127_3217817_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
PYH1_k127_3217817_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000005315 142.0
PYH1_k127_331057_0 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 338.0
PYH1_k127_331057_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
PYH1_k127_331057_2 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003136 248.0
PYH1_k127_331057_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000001083 217.0
PYH1_k127_331057_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000005042 94.0
PYH1_k127_331057_5 - - - - 0.0000002358 59.0
PYH1_k127_331321_0 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008607 259.0
PYH1_k127_331321_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21030 - 2.7.7.40,2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000008871 237.0
PYH1_k127_331321_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000634 82.0
PYH1_k127_3325625_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.983e-275 864.0
PYH1_k127_3325625_1 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
PYH1_k127_3325625_2 Belongs to the Smg family K03747 - - 0.00004961 52.0
PYH1_k127_3359731_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 357.0
PYH1_k127_3359731_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 346.0
PYH1_k127_3359731_10 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000002256 136.0
PYH1_k127_3359731_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 338.0
PYH1_k127_3359731_3 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 329.0
PYH1_k127_3359731_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 301.0
PYH1_k127_3359731_5 CMP dCMP deaminase, zinc-binding - - - 0.00000000000000000000000000000000000000000000000000000000000001004 226.0
PYH1_k127_3359731_6 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000006527 180.0
PYH1_k127_3359731_7 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000005656 166.0
PYH1_k127_3359731_8 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000002846 140.0
PYH1_k127_3359731_9 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000003568 139.0
PYH1_k127_3375877_0 ATPase BadF BadG BcrA BcrD type - - - 2.282e-315 996.0
PYH1_k127_3381685_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 501.0
PYH1_k127_3381685_1 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 378.0
PYH1_k127_3381685_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005793 281.0
PYH1_k127_3381685_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000007083 187.0
PYH1_k127_3381685_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000001933 117.0
PYH1_k127_3381685_5 antisigma factor binding K04749 - - 0.00000000000000449 80.0
PYH1_k127_3381685_6 Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family K02003,K02004 - - 0.00000005622 55.0
PYH1_k127_3381685_7 PBS lyase HEAT-like repeat - - - 0.00001515 57.0
PYH1_k127_3385388_0 diguanylate cyclase - - - 0.00000000000000000000000000003994 135.0
PYH1_k127_3385388_1 Protein of unknown function (DUF507) - - - 0.000000000004491 70.0
PYH1_k127_3385388_2 Predicted membrane protein (DUF2232) - - - 0.00000000009181 73.0
PYH1_k127_3385388_3 Protein of unknown function (DUF507) - - - 0.0000000004959 65.0
PYH1_k127_3385388_4 rRNA binding K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000004107 57.0
PYH1_k127_3386176_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 532.0
PYH1_k127_3386176_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000003474 190.0
PYH1_k127_3393487_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 352.0
PYH1_k127_3393487_1 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005558 281.0
PYH1_k127_3393487_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000005954 71.0
PYH1_k127_3402721_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 297.0
PYH1_k127_3402721_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000003545 230.0
PYH1_k127_3402721_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000003109 166.0
PYH1_k127_3402721_3 PFAM CBS domain - - - 0.00000000000000000000000000000000000000001488 157.0
PYH1_k127_3407431_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 553.0
PYH1_k127_3407431_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 323.0
PYH1_k127_3407431_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000001675 203.0
PYH1_k127_3426350_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 479.0
PYH1_k127_3426350_1 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000006608 144.0
PYH1_k127_3450782_0 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 441.0
PYH1_k127_3450782_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 442.0
PYH1_k127_3450782_10 - - - - 0.00002718 56.0
PYH1_k127_3450782_11 Family of unknown function (DUF5336) - - - 0.0005894 52.0
PYH1_k127_3450782_2 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 418.0
PYH1_k127_3450782_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 377.0
PYH1_k127_3450782_4 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 331.0
PYH1_k127_3450782_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007071 274.0
PYH1_k127_3450782_6 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000004008 185.0
PYH1_k127_3450782_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000001221 97.0
PYH1_k127_3450782_8 Helix-turn-helix domain - - - 0.0000000000000001344 91.0
PYH1_k127_3450782_9 peptidyl-tyrosine sulfation - - - 0.00000000000005617 83.0
PYH1_k127_3451978_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 384.0
PYH1_k127_3451978_1 Bacterial regulatory proteins, crp family K01420 - - 0.0000000000000000000000000000000000000000000005663 174.0
PYH1_k127_3451978_2 FecR protein - - - 0.0000003665 60.0
PYH1_k127_3455326_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
PYH1_k127_3455326_1 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 300.0
PYH1_k127_3455326_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000004805 117.0
PYH1_k127_3455326_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000005542 105.0
PYH1_k127_3455326_5 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001016 98.0
PYH1_k127_3455885_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 574.0
PYH1_k127_3455885_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 356.0
PYH1_k127_3462484_0 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 388.0
PYH1_k127_3462484_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 338.0
PYH1_k127_3462484_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
PYH1_k127_3462484_3 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008876 281.0
PYH1_k127_3462484_4 S4 domain protein - - - 0.0000000000000038 84.0
PYH1_k127_3465082_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
PYH1_k127_3465082_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 426.0
PYH1_k127_3465082_2 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000001644 125.0
PYH1_k127_3478991_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 362.0
PYH1_k127_3478991_1 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 310.0
PYH1_k127_3478991_2 ferrous iron binding K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000005308 198.0
PYH1_k127_3478991_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000246 94.0
PYH1_k127_3478991_5 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0002378 45.0
PYH1_k127_3485699_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 471.0
PYH1_k127_3485699_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000002073 159.0
PYH1_k127_3485699_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000002501 124.0
PYH1_k127_3485699_3 protein phosphatase 2C domain protein - - - 0.0000000001515 71.0
PYH1_k127_3487313_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1469.0
PYH1_k127_3487313_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 295.0
PYH1_k127_3487313_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000008487 146.0
PYH1_k127_3487313_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000003067 119.0
PYH1_k127_3487313_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000007624 93.0
PYH1_k127_3493653_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 494.0
PYH1_k127_3493653_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 306.0
PYH1_k127_3493653_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004518 251.0
PYH1_k127_3493653_3 helix_turn_helix, mercury resistance - - - 0.0000000000000000003302 96.0
PYH1_k127_3493653_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000001239 70.0
PYH1_k127_3493653_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000002923 72.0
PYH1_k127_3493653_6 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000803 51.0
PYH1_k127_3505470_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 605.0
PYH1_k127_3505470_1 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000007532 161.0
PYH1_k127_3505470_2 - - - - 0.000000000000000000222 92.0
PYH1_k127_3505470_3 RmuC family K09760 - - 0.000000005667 58.0
PYH1_k127_3509877_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 319.0
PYH1_k127_3509877_1 PFAM Cupin - - - 0.000000000000000000000000000000000000000000006766 166.0
PYH1_k127_3509877_2 SMART Cold shock protein K03704 - - 0.00000000000000000000002757 106.0
PYH1_k127_3509877_3 AMP-binding enzyme C-terminal domain - - - 0.000001676 54.0
PYH1_k127_3532371_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.081e-234 731.0
PYH1_k127_3532371_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 294.0
PYH1_k127_3532371_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000008646 248.0
PYH1_k127_3566801_0 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 334.0
PYH1_k127_3566801_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000478 284.0
PYH1_k127_3566801_2 membrane organization K20543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000515 267.0
PYH1_k127_3566801_3 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000374 242.0
PYH1_k127_3566801_4 CGGC - - - 0.0000000000000000000000000000000000000000000000000000000008397 205.0
PYH1_k127_3566801_5 double-strand break repair protein AddB K16899 - 3.6.4.12 0.00000000000000000000683 104.0
PYH1_k127_3566801_6 translation initiation factor activity K03646 - - 0.0001873 50.0
PYH1_k127_3584764_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.995e-212 668.0
PYH1_k127_3584764_1 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 584.0
PYH1_k127_3584764_10 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000004239 235.0
PYH1_k127_3584764_11 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000308 188.0
PYH1_k127_3584764_12 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000006203 186.0
PYH1_k127_3584764_13 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000006225 180.0
PYH1_k127_3584764_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000001244 134.0
PYH1_k127_3584764_15 cobalt ion transport K02009 - - 0.000000000000000000000000000202 119.0
PYH1_k127_3584764_16 PBS lyase HEAT-like repeat - - - 0.000000000000003714 90.0
PYH1_k127_3584764_18 - - - - 0.0000009881 50.0
PYH1_k127_3584764_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 570.0
PYH1_k127_3584764_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 301.0
PYH1_k127_3584764_4 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 295.0
PYH1_k127_3584764_5 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 264.0
PYH1_k127_3584764_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000001094 252.0
PYH1_k127_3584764_7 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001439 248.0
PYH1_k127_3584764_8 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001732 241.0
PYH1_k127_3584764_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001049 233.0
PYH1_k127_3600101_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 507.0
PYH1_k127_3600101_1 Putative metallopeptidase - - - 0.000000000000000000008122 104.0
PYH1_k127_3620315_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1135.0
PYH1_k127_3620315_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 357.0
PYH1_k127_3620315_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000002282 100.0
PYH1_k127_3620315_11 Sporulation and spore germination - - - 0.000000000000002903 83.0
PYH1_k127_3620315_13 Ami_3 K01448 - 3.5.1.28 0.0000000001056 73.0
PYH1_k127_3620315_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000003703 63.0
PYH1_k127_3620315_15 rhodanese-related sulfurtransferase - - - 0.0005305 48.0
PYH1_k127_3620315_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 323.0
PYH1_k127_3620315_3 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 306.0
PYH1_k127_3620315_4 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001063 251.0
PYH1_k127_3620315_5 - K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
PYH1_k127_3620315_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000002978 220.0
PYH1_k127_3620315_7 - K07112 - - 0.0000000000000000000000000000000000000000000000000003421 193.0
PYH1_k127_3620315_8 CutA1 divalent ion tolerance protein K01733,K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 4.2.3.1 0.00000000000000000000000000165 115.0
PYH1_k127_3620315_9 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000001916 112.0
PYH1_k127_3630496_0 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000004854 158.0
PYH1_k127_3630496_1 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000001484 128.0
PYH1_k127_3630496_2 isopentenyl-diphosphate delta-isomerase activity - - - 0.0000000000000000000000000002456 126.0
PYH1_k127_3630496_3 Thioredoxin domain - - - 0.0000000000000001161 84.0
PYH1_k127_3630496_4 Iron-sulphur cluster biosynthesis K13628 - - 0.00007796 47.0
PYH1_k127_3630890_0 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 347.0
PYH1_k127_3630890_1 - - - - 0.00000000000000000000000000000001453 137.0
PYH1_k127_3630890_2 AsmA-like C-terminal region - - - 0.00000000000000000000000438 117.0
PYH1_k127_3630890_3 Domain of unknown function (DUF4136) - - - 0.00000000000000002242 89.0
PYH1_k127_3635163_0 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 339.0
PYH1_k127_3635163_1 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
PYH1_k127_3635163_2 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000151 231.0
PYH1_k127_3635163_3 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000006131 195.0
PYH1_k127_3635163_4 HupE / UreJ protein - - - 0.0000000000000000000000000000000005218 144.0
PYH1_k127_3645860_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000004357 266.0
PYH1_k127_3645860_1 Iron-sulfur cluster-binding domain K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001352 245.0
PYH1_k127_3645860_2 auxin-activated signaling pathway K07088 - - 0.0000000000000000000000000000000000000000000000000000006746 204.0
PYH1_k127_3645860_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000001105 161.0
PYH1_k127_365364_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008299 244.0
PYH1_k127_365364_1 PFAM PHP domain - - - 0.00000000000000000000000000000000000000003452 160.0
PYH1_k127_365364_2 - - - - 0.0000000000000000000000000000000000000002311 158.0
PYH1_k127_365364_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000274 119.0
PYH1_k127_365364_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000000003774 103.0
PYH1_k127_365364_5 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000005732 86.0
PYH1_k127_365364_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000001835 64.0
PYH1_k127_365364_7 cheY-homologous receiver domain - - - 0.00004194 54.0
PYH1_k127_3656815_0 CBS domain containing protein K00974 - 2.7.7.72 1.037e-259 827.0
PYH1_k127_3656815_1 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 396.0
PYH1_k127_3656815_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 364.0
PYH1_k127_3656815_3 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 313.0
PYH1_k127_3656815_4 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000013 220.0
PYH1_k127_3656815_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000002588 196.0
PYH1_k127_3656815_6 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000008649 186.0
PYH1_k127_3656815_7 Rhs Family K20276 - - 0.000000000000002245 88.0
PYH1_k127_3656815_8 Sporulation related domain - - - 0.00000000003638 74.0
PYH1_k127_3656815_9 self proteolysis - - - 0.00000001733 60.0
PYH1_k127_368281_0 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 357.0
PYH1_k127_368281_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 314.0
PYH1_k127_368281_2 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000003418 197.0
PYH1_k127_368281_3 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000001369 173.0
PYH1_k127_3689852_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 4.986e-240 778.0
PYH1_k127_3689852_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
PYH1_k127_3689852_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000002344 147.0
PYH1_k127_3689852_3 Thioesterase superfamily - - - 0.0000000000000000000000008488 108.0
PYH1_k127_3693663_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
PYH1_k127_3693663_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 363.0
PYH1_k127_3693663_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 291.0
PYH1_k127_3695855_0 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 555.0
PYH1_k127_3695855_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 390.0
PYH1_k127_37004_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 522.0
PYH1_k127_37004_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
PYH1_k127_37004_2 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000006486 98.0
PYH1_k127_3722310_0 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 529.0
PYH1_k127_3722310_1 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001149 263.0
PYH1_k127_3722310_2 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003372 234.0
PYH1_k127_3722310_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000003115 152.0
PYH1_k127_3722310_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000003596 140.0
PYH1_k127_3722310_5 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.0003196 46.0
PYH1_k127_3726505_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 447.0
PYH1_k127_3726505_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 390.0
PYH1_k127_3726505_2 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 293.0
PYH1_k127_3745581_0 GMC oxidoreductase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 5.356e-215 680.0
PYH1_k127_3745581_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 322.0
PYH1_k127_3745581_2 Phospholipase D. Active site motifs. K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.00000000000000000000000000000003981 130.0
PYH1_k127_3779326_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 601.0
PYH1_k127_3779326_1 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 439.0
PYH1_k127_3779326_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 426.0
PYH1_k127_3779326_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 430.0
PYH1_k127_3779326_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000008363 207.0
PYH1_k127_3779326_5 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000003005 66.0
PYH1_k127_378943_0 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 2.774e-198 625.0
PYH1_k127_378943_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 295.0
PYH1_k127_378943_2 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001722 251.0
PYH1_k127_378943_3 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000003875 150.0
PYH1_k127_3815987_0 General secretory system II, protein E domain protein K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 612.0
PYH1_k127_3815987_1 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003467 262.0
PYH1_k127_3815987_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000001318 75.0
PYH1_k127_3833376_0 long-chain fatty acid transport protein - - - 4.412e-236 750.0
PYH1_k127_3833376_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 418.0
PYH1_k127_3833376_2 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 396.0
PYH1_k127_3833376_3 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH1_k127_3833376_4 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000904 252.0
PYH1_k127_3833376_5 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000004352 234.0
PYH1_k127_3833376_6 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000647 189.0
PYH1_k127_3833376_7 - - - - 0.000000000000000000000003722 110.0
PYH1_k127_3843473_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1073.0
PYH1_k127_3843473_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 2.395e-206 657.0
PYH1_k127_3843473_10 - - - - 0.0000000000000000001547 91.0
PYH1_k127_3843473_2 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 604.0
PYH1_k127_3843473_3 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 533.0
PYH1_k127_3843473_4 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 478.0
PYH1_k127_3843473_5 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 332.0
PYH1_k127_3843473_6 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003125 280.0
PYH1_k127_3843473_7 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000004389 254.0
PYH1_k127_3843473_8 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000004579 145.0
PYH1_k127_3843473_9 cyclic nucleotide-binding - - - 0.0000000000000000000000000000007301 130.0
PYH1_k127_3845067_0 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 374.0
PYH1_k127_3845067_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000003606 213.0
PYH1_k127_3845067_2 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000005201 95.0
PYH1_k127_3845067_3 PFAM 4Fe-4S ferredoxin - - - 0.00000000000000003155 83.0
PYH1_k127_3845067_4 NifU-like N terminal domain - - - 0.00000189 50.0
PYH1_k127_3870117_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 527.0
PYH1_k127_3870117_1 pfam abc K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 297.0
PYH1_k127_3870117_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000004138 227.0
PYH1_k127_3870117_3 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000001063 100.0
PYH1_k127_3968533_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 374.0
PYH1_k127_3968533_1 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 349.0
PYH1_k127_3968533_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
PYH1_k127_3968533_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000008694 110.0
PYH1_k127_3968533_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000008475 83.0
PYH1_k127_3968533_5 cell envelope organization K05807,K08309 - - 0.000000000002433 77.0
PYH1_k127_3968533_6 protein related to C-terminal domain of eukaryotic chaperone SACSIN - - - 0.0001873 50.0
PYH1_k127_3969002_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 319.0
PYH1_k127_3969002_1 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000001939 183.0
PYH1_k127_4030725_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 319.0
PYH1_k127_4030725_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001853 265.0
PYH1_k127_4030725_2 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000001272 188.0
PYH1_k127_4030725_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.00000000000002532 84.0
PYH1_k127_4030725_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000004406 51.0
PYH1_k127_4105843_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.432e-313 972.0
PYH1_k127_4105843_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000005544 149.0
PYH1_k127_4105843_2 lipoprotein involved in nitrous oxide reduction - - - 0.00000009747 57.0
PYH1_k127_4187436_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 605.0
PYH1_k127_4187436_1 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000000004361 151.0
PYH1_k127_4187436_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0001024 46.0
PYH1_k127_4205994_0 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 367.0
PYH1_k127_4205994_1 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 314.0
PYH1_k127_4205994_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001746 249.0
PYH1_k127_4205994_3 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000001748 214.0
PYH1_k127_4205994_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000349 156.0
PYH1_k127_4212474_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 606.0
PYH1_k127_4212474_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 486.0
PYH1_k127_4212474_2 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 396.0
PYH1_k127_4212474_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000000000009453 192.0
PYH1_k127_4212474_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000001521 138.0
PYH1_k127_4212474_5 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000001879 126.0
PYH1_k127_4212474_6 Rhodanese domain protein - - - 0.0000000000000000001931 94.0
PYH1_k127_4212474_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000002375 81.0
PYH1_k127_4212474_8 Putative regulatory protein - - - 0.000004514 51.0
PYH1_k127_4212474_9 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0002916 46.0
PYH1_k127_4239787_0 GMP synthase C terminal domain K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 556.0
PYH1_k127_4239787_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 476.0
PYH1_k127_4239787_2 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 455.0
PYH1_k127_4239787_3 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
PYH1_k127_4239787_4 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000003414 143.0
PYH1_k127_4248204_0 Belongs to the aldehyde dehydrogenase family K00128,K00129 - 1.2.1.3,1.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 565.0
PYH1_k127_4248204_1 Histidine Phosphotransfer domain K03413,K07662,K07667,K11443 - - 0.00000000000000000000000000000000000000001263 168.0
PYH1_k127_4248204_2 Domain of unknown function (DUF4149) - - - 0.00002533 48.0
PYH1_k127_4278468_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1132.0
PYH1_k127_4278468_1 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000002461 122.0
PYH1_k127_4278468_2 Conserved carboxylase domain K01958 - 6.4.1.1 0.000000000000000003463 84.0
PYH1_k127_4297183_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 576.0
PYH1_k127_4297183_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000003182 200.0
PYH1_k127_4297183_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000037 147.0
PYH1_k127_4305762_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 436.0
PYH1_k127_4305762_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000001547 53.0
PYH1_k127_4313560_0 Cache domain - - - 1.392e-245 772.0
PYH1_k127_4313560_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 363.0
PYH1_k127_4313560_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
PYH1_k127_4313560_3 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000004833 224.0
PYH1_k127_4313560_4 PFAM PASTA domain - - - 0.00000000000000001 93.0
PYH1_k127_4313749_0 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000002524 118.0
PYH1_k127_4313749_1 Papain-like cysteine protease AvrRpt2 - - - 0.000000000000000000000008383 109.0
PYH1_k127_4313749_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.000000000002004 72.0
PYH1_k127_4313749_4 - - - - 0.0003695 46.0
PYH1_k127_4316033_0 Domain of unknown function (DUF4139) - - - 1.059e-204 647.0
PYH1_k127_4316033_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 291.0
PYH1_k127_4316033_2 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002324 250.0
PYH1_k127_4316033_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000004444 194.0
PYH1_k127_4316033_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000003386 163.0
PYH1_k127_4316033_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000485 118.0
PYH1_k127_4316033_6 Putative zinc-finger - - - 0.0000000000000009895 89.0
PYH1_k127_4317470_0 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000004265 231.0
PYH1_k127_4317470_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000002787 222.0
PYH1_k127_4317470_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000002969 146.0
PYH1_k127_4317470_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000002815 78.0
PYH1_k127_4360295_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 430.0
PYH1_k127_4360295_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 391.0
PYH1_k127_4360295_2 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000002166 202.0
PYH1_k127_4360295_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000001358 151.0
PYH1_k127_4370618_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1520.0
PYH1_k127_4370618_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 493.0
PYH1_k127_4370618_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 367.0
PYH1_k127_4370618_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 357.0
PYH1_k127_4370618_4 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000002615 143.0
PYH1_k127_4370618_5 YtkA-like - - - 0.000000000000000000000000004403 116.0
PYH1_k127_4370618_6 Outer membrane lipoprotein - - - 0.000000000000000000000002216 116.0
PYH1_k127_4377760_0 SMART Elongator protein 3 MiaB NifB - - - 1.103e-204 646.0
PYH1_k127_4377760_1 GAF domain - - - 0.0000000000000000000000000000000000225 139.0
PYH1_k127_447548_0 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 343.0
PYH1_k127_447548_1 Type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000004992 192.0
PYH1_k127_447548_2 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000005364 112.0
PYH1_k127_447548_3 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000001429 107.0
PYH1_k127_447548_4 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000426 100.0
PYH1_k127_447548_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.0000000000000007364 80.0
PYH1_k127_4498637_0 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002945 269.0
PYH1_k127_4498637_1 HD domain - - - 0.000000000000000000000000000000000000000000824 167.0
PYH1_k127_4498637_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000001011 56.0
PYH1_k127_4522789_0 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 520.0
PYH1_k127_4522789_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 505.0
PYH1_k127_4522789_2 Ion channel K10716 - - 0.0000000000000000000000000000000000000006128 151.0
PYH1_k127_4533424_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.792e-229 734.0
PYH1_k127_4533424_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 464.0
PYH1_k127_4533424_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000002391 265.0
PYH1_k127_4533424_3 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002899 233.0
PYH1_k127_4533424_4 protein with SCP PR1 domains - - - 0.0000000000000000000000000000000000000000000000000004483 191.0
PYH1_k127_4533424_5 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000002225 158.0
PYH1_k127_4533424_6 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000002458 134.0
PYH1_k127_4533424_7 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000007323 76.0
PYH1_k127_4533424_8 lipoprotein involved in nitrous oxide reduction - - - 0.000000002483 66.0
PYH1_k127_4599399_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.646e-217 683.0
PYH1_k127_4599399_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
PYH1_k127_4599399_2 radical SAM domain protein - - - 0.0003874 48.0
PYH1_k127_4615550_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 590.0
PYH1_k127_4615550_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 588.0
PYH1_k127_4615550_2 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 415.0
PYH1_k127_4615550_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002317 277.0
PYH1_k127_4615550_4 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
PYH1_k127_4615550_5 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000003433 69.0
PYH1_k127_4615550_6 - - - - 0.0000000002171 64.0
PYH1_k127_4663884_0 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 406.0
PYH1_k127_4663884_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 352.0
PYH1_k127_4663884_10 - - - - 0.0000000000000000000000000000000000000000000000000001101 208.0
PYH1_k127_4663884_11 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000006056 192.0
PYH1_k127_4663884_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000007824 178.0
PYH1_k127_4663884_13 Peptide nickel ABC transporter, permease K02034 - - 0.0000000000000000000000000000000000000000000000131 192.0
PYH1_k127_4663884_14 NmrA-like family - - - 0.00000000000000000000000000003788 125.0
PYH1_k127_4663884_15 - - - - 0.0000000000000000000000000001449 122.0
PYH1_k127_4663884_16 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000004088 110.0
PYH1_k127_4663884_17 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000003321 113.0
PYH1_k127_4663884_19 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0003911 54.0
PYH1_k127_4663884_2 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 363.0
PYH1_k127_4663884_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 340.0
PYH1_k127_4663884_4 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 301.0
PYH1_k127_4663884_5 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
PYH1_k127_4663884_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004279 271.0
PYH1_k127_4663884_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
PYH1_k127_4663884_8 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000002787 203.0
PYH1_k127_4663884_9 - - - - 0.00000000000000000000000000000000000000000000000000006315 189.0
PYH1_k127_4677772_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 476.0
PYH1_k127_4677772_1 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
PYH1_k127_4677772_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000003759 203.0
PYH1_k127_4677772_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH1_k127_4677772_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000005641 156.0
PYH1_k127_4677772_5 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.00000000000000000000000000000000000000007028 154.0
PYH1_k127_4677772_6 part of a sulfur-relay system K11179 - - 0.0000000000000000000000006636 108.0
PYH1_k127_4677772_7 Cold shock K03704 - - 0.0000000000000000000000016 103.0
PYH1_k127_4730306_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.523e-319 995.0
PYH1_k127_4730306_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 324.0
PYH1_k127_4730306_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 295.0
PYH1_k127_4730306_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000002037 114.0
PYH1_k127_4730306_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000001079 97.0
PYH1_k127_4730306_5 - - - - 0.000000005867 56.0
PYH1_k127_4783986_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 493.0
PYH1_k127_4783986_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 420.0
PYH1_k127_4783986_2 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000005376 225.0
PYH1_k127_4783986_3 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.00000000000000000000000000000000000000000000000007637 183.0
PYH1_k127_4836116_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 504.0
PYH1_k127_4836116_1 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001017 273.0
PYH1_k127_4836116_2 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000000000000000000000000002252 176.0
PYH1_k127_4836116_3 HEPN domain - - - 0.00000000000000003792 87.0
PYH1_k127_4838520_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 404.0
PYH1_k127_4838520_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004407 256.0
PYH1_k127_4838520_2 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001267 219.0
PYH1_k127_4838520_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000005805 224.0
PYH1_k127_4838520_4 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000007125 191.0
PYH1_k127_4845864_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 466.0
PYH1_k127_4845864_1 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 316.0
PYH1_k127_4845864_2 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 306.0
PYH1_k127_4845864_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000005005 82.0
PYH1_k127_4845864_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000002899 61.0
PYH1_k127_4893847_0 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 337.0
PYH1_k127_4893847_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 325.0
PYH1_k127_4893847_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000051 213.0
PYH1_k127_4893847_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000006758 131.0
PYH1_k127_4893990_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 291.0
PYH1_k127_4893990_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001443 271.0
PYH1_k127_4893990_2 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004876 247.0
PYH1_k127_4893990_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000002118 199.0
PYH1_k127_4893990_4 YGGT family K02221 - - 0.00000000000000000000000000003864 120.0
PYH1_k127_4893990_5 DivIVA protein K04074 - - 0.0000000000000000000000000002316 120.0
PYH1_k127_4893990_6 Belongs to the UPF0235 family K09131 - - 0.000000000000000000002624 96.0
PYH1_k127_4897004_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 1.063e-196 637.0
PYH1_k127_4897004_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 490.0
PYH1_k127_4897004_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 459.0
PYH1_k127_4897004_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 422.0
PYH1_k127_4897004_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 326.0
PYH1_k127_4897004_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
PYH1_k127_4897004_6 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000000000000000001109 201.0
PYH1_k127_4897004_7 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000005431 182.0
PYH1_k127_4897004_8 Cell surface protein - - - 0.00000000000000000006305 105.0
PYH1_k127_491769_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 4.79e-207 655.0
PYH1_k127_491769_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 582.0
PYH1_k127_491769_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 482.0
PYH1_k127_491769_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000001201 170.0
PYH1_k127_491769_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000001372 117.0
PYH1_k127_4964205_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 561.0
PYH1_k127_4964205_1 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000000005827 146.0
PYH1_k127_4964205_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000193 132.0
PYH1_k127_4964205_3 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000001944 121.0
PYH1_k127_496968_0 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000346 186.0
PYH1_k127_496968_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000002769 141.0
PYH1_k127_496968_2 Domain of unknown function (DUF4388) - - - 0.00000000000158 81.0
PYH1_k127_496968_3 Domain of unknown function (DUF3395) K09531 GO:0001671,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008047,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0017038,GO:0019867,GO:0030150,GO:0030234,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032781,GO:0033036,GO:0033365,GO:0034613,GO:0042407,GO:0042886,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044093,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051336,GO:0051345,GO:0051641,GO:0051649,GO:0055085,GO:0060589,GO:0060590,GO:0061024,GO:0065002,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0098588,GO:0098772,GO:0098805,GO:1990542 - 0.000000005009 69.0
PYH1_k127_498173_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000005069 202.0
PYH1_k127_498173_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000000002611 162.0
PYH1_k127_498173_2 - - - - 0.0000000000000000000000000000007981 124.0
PYH1_k127_498173_3 - - - - 0.00000001488 56.0
PYH1_k127_5049381_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1160.0
PYH1_k127_5049381_1 proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 299.0
PYH1_k127_5049381_2 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004843 256.0
PYH1_k127_5049381_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000001193 216.0
PYH1_k127_5049381_4 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000000000000000646 163.0
PYH1_k127_5049381_5 Response regulator receiver domain - - - 0.00000000000000000000000000000000000001468 149.0
PYH1_k127_5049381_6 - - - - 0.0000000000000000000000000006242 121.0
PYH1_k127_5049381_7 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000006697 115.0
PYH1_k127_5074961_0 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 437.0
PYH1_k127_5074961_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 346.0
PYH1_k127_5074961_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 285.0
PYH1_k127_5074961_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003477 269.0
PYH1_k127_5074961_4 cyclic nucleotide-binding K10914 - - 0.000003497 51.0
PYH1_k127_5077042_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 315.0
PYH1_k127_5077042_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000005825 259.0
PYH1_k127_5077042_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000001248 139.0
PYH1_k127_5077042_3 Could be involved in septation K06412 - - 0.000000000000000000000000000000001494 132.0
PYH1_k127_5098602_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1371.0
PYH1_k127_5098602_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 322.0
PYH1_k127_5098602_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000001095 229.0
PYH1_k127_5098602_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001335 217.0
PYH1_k127_5098602_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000005185 177.0
PYH1_k127_5098602_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000005491 170.0
PYH1_k127_5098602_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000001971 88.0
PYH1_k127_5098602_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008823 74.0
PYH1_k127_5098602_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000001631 65.0
PYH1_k127_5114470_0 aconitate hydratase K01681 - 4.2.1.3 3.538e-280 875.0
PYH1_k127_5114470_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.298e-209 663.0
PYH1_k127_5114470_10 cysteine-type peptidase activity K19223 - - 0.00004244 52.0
PYH1_k127_5114470_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 435.0
PYH1_k127_5114470_3 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000003742 225.0
PYH1_k127_5114470_4 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000002743 167.0
PYH1_k127_5114470_5 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000633 144.0
PYH1_k127_5114470_6 Universal stress protein family - - - 0.00000000000000000000000000000000007857 139.0
PYH1_k127_5114470_7 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000005432 127.0
PYH1_k127_5114470_8 Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing - - - 0.00000000000000000000001122 117.0
PYH1_k127_5114470_9 NlpC/P60 family K20742 - 3.4.14.13 0.00000000000008328 83.0
PYH1_k127_5115284_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000006675 254.0
PYH1_k127_5115284_1 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000008925 221.0
PYH1_k127_5126817_0 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 565.0
PYH1_k127_5126817_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001574 248.0
PYH1_k127_5126817_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000008278 48.0
PYH1_k127_5126817_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000001224 184.0
PYH1_k127_5126817_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000297 152.0
PYH1_k127_5126817_4 PTS system mannose fructose sorbose family IID component K02795,K02796 - - 0.000000000000000000000000000000005351 138.0
PYH1_k127_5126817_5 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000001255 121.0
PYH1_k127_5126817_6 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000000001706 124.0
PYH1_k127_5126817_7 PTS system sorbose subfamily IIB component K02769,K02793,K02794 - 2.7.1.191,2.7.1.202 0.000000000000000000000000001115 118.0
PYH1_k127_5126817_8 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000001016 100.0
PYH1_k127_5126817_9 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000005704 96.0
PYH1_k127_5133418_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.484e-213 670.0
PYH1_k127_5133418_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 544.0
PYH1_k127_5133418_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 506.0
PYH1_k127_5133418_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 454.0
PYH1_k127_5133418_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 396.0
PYH1_k127_5133418_5 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 333.0
PYH1_k127_5133418_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000003729 224.0
PYH1_k127_5133418_7 Binds the 23S rRNA K02909 - - 0.000000000000000000000001819 106.0
PYH1_k127_5133418_8 SMART Tetratricopeptide - - - 0.0000001793 57.0
PYH1_k127_5157624_0 PFAM ABC transporter related K06020 - 3.6.3.25 6.903e-209 654.0
PYH1_k127_5157624_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000001371 175.0
PYH1_k127_5157624_3 - - - - 0.00000004912 64.0
PYH1_k127_5157624_4 - - - - 0.0000002551 59.0
PYH1_k127_5157624_5 Predicted membrane protein (DUF2207) - - - 0.000103 53.0
PYH1_k127_5181337_0 helicase activity K06915,K19172 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 391.0
PYH1_k127_5181337_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 370.0
PYH1_k127_5181337_2 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 316.0
PYH1_k127_5181337_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000001364 233.0
PYH1_k127_5181337_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000155 233.0
PYH1_k127_5181337_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000003978 98.0
PYH1_k127_5181337_6 Protein conserved in bacteria K11719 - - 0.00000000012 70.0
PYH1_k127_5181884_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1021.0
PYH1_k127_5181884_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000004365 188.0
PYH1_k127_5181884_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000002585 126.0
PYH1_k127_5181884_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000003202 91.0
PYH1_k127_5181884_4 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000008181 74.0
PYH1_k127_5188800_0 Heat shock 70 kDa protein K04043 - - 1.442e-300 934.0
PYH1_k127_5188800_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 581.0
PYH1_k127_5188800_10 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
PYH1_k127_5188800_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000335 194.0
PYH1_k127_5188800_12 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000008038 192.0
PYH1_k127_5188800_13 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000002154 167.0
PYH1_k127_5188800_14 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000002203 136.0
PYH1_k127_5188800_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000007995 130.0
PYH1_k127_5188800_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000007335 119.0
PYH1_k127_5188800_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 566.0
PYH1_k127_5188800_3 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 567.0
PYH1_k127_5188800_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 543.0
PYH1_k127_5188800_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 399.0
PYH1_k127_5188800_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 374.0
PYH1_k127_5188800_7 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 313.0
PYH1_k127_5188800_8 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 312.0
PYH1_k127_5188800_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 291.0
PYH1_k127_5207920_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 327.0
PYH1_k127_5207920_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000388 199.0
PYH1_k127_5207920_2 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000001936 154.0
PYH1_k127_5207920_3 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000002256 81.0
PYH1_k127_5246955_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.908e-263 824.0
PYH1_k127_5246955_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000001178 134.0
PYH1_k127_5256732_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.863e-237 741.0
PYH1_k127_5256732_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000001787 245.0
PYH1_k127_5256732_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000002259 204.0
PYH1_k127_5256732_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000003281 195.0
PYH1_k127_5256732_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000004546 195.0
PYH1_k127_5256732_5 Histidine kinase K07636 - 2.7.13.3 0.000000000004161 78.0
PYH1_k127_5276237_0 fibronectin type III domain protein K06882 - - 3.313e-200 671.0
PYH1_k127_5276237_1 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 406.0
PYH1_k127_5276237_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 337.0
PYH1_k127_5276237_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007111 265.0
PYH1_k127_5276237_4 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000000002549 113.0
PYH1_k127_5276237_5 DNA-directed DNA polymerase activity - - - 0.00000000000001412 88.0
PYH1_k127_5276237_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000002683 76.0
PYH1_k127_5276237_7 - - - - 0.00000918 54.0
PYH1_k127_5295717_0 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 613.0
PYH1_k127_5295717_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 486.0
PYH1_k127_5295717_2 Capsule polysaccharide biosynthesis protein K07265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 403.0
PYH1_k127_5295717_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000001322 108.0
PYH1_k127_5296957_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 598.0
PYH1_k127_5296957_1 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000001052 128.0
PYH1_k127_5300985_0 PFAM Radical SAM - - - 6.606e-204 646.0
PYH1_k127_5300985_1 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000000000000000001455 203.0
PYH1_k127_5300985_2 oligopeptide transporter - - - 0.0001075 47.0
PYH1_k127_5301390_0 Fatty acid cis/trans isomerase (CTI) - - - 1.052e-308 953.0
PYH1_k127_5305760_0 Neisseria PilC beta-propeller domain K02674 - - 1.974e-269 879.0
PYH1_k127_5305760_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000007627 199.0
PYH1_k127_5305760_2 Prokaryotic N-terminal methylation motif - - - 0.000000000871 66.0
PYH1_k127_5305760_3 - - - - 0.0000001446 62.0
PYH1_k127_5305760_4 self proteolysis - - - 0.0001268 53.0
PYH1_k127_5305760_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08084 - - 0.00058 51.0
PYH1_k127_5310511_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 483.0
PYH1_k127_5310511_1 cell cycle K05589,K12065,K13052 - - 0.000000009582 61.0
PYH1_k127_5330664_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 437.0
PYH1_k127_5330664_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 404.0
PYH1_k127_5330664_2 response regulator receiver K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000001053 235.0
PYH1_k127_5330664_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000007923 241.0
PYH1_k127_5330664_4 - - - - 0.000000000000000000000000002305 122.0
PYH1_k127_5330664_5 Heavy metal transport detoxification protein K07213 - - 0.0000000000006261 70.0
PYH1_k127_5345321_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 360.0
PYH1_k127_5345321_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000003111 200.0
PYH1_k127_5346801_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 9.335e-221 719.0
PYH1_k127_5346801_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 330.0
PYH1_k127_5346801_2 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000008438 198.0
PYH1_k127_5346801_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000001731 102.0
PYH1_k127_5346801_4 - - - - 0.0003276 44.0
PYH1_k127_5356938_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.539e-197 629.0
PYH1_k127_5356938_1 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 382.0
PYH1_k127_5356938_2 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 390.0
PYH1_k127_5356938_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 341.0
PYH1_k127_5356938_4 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000316 213.0
PYH1_k127_5356938_5 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000001286 194.0
PYH1_k127_5356938_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000002133 119.0
PYH1_k127_5356938_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000000000000000000000005497 119.0
PYH1_k127_5356938_8 Roadblock/LC7 domain - - - 0.000000000009902 69.0
PYH1_k127_5357251_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 335.0
PYH1_k127_5357251_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 316.0
PYH1_k127_5357251_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 291.0
PYH1_k127_5357251_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005865 282.0
PYH1_k127_5357251_4 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000838 229.0
PYH1_k127_5357251_5 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000007905 129.0
PYH1_k127_5376894_0 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 306.0
PYH1_k127_5376894_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000001705 192.0
PYH1_k127_5376894_2 Protein of unknown function (DUF2845) - - - 0.0000000000000000000000000000000003 138.0
PYH1_k127_5376894_3 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000788 84.0
PYH1_k127_5449708_0 PFAM MscS Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 322.0
PYH1_k127_5449708_1 Protein of unknown function (DUF3570) - - - 0.00000000004386 70.0
PYH1_k127_5449708_2 response regulator - - - 0.000000000723 69.0
PYH1_k127_5458141_0 Sulfatase K01130 - 3.1.6.1 0.0 1429.0
PYH1_k127_5458141_1 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000009954 106.0
PYH1_k127_5458141_2 - - - - 0.00003922 47.0
PYH1_k127_548842_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 481.0
PYH1_k127_548842_1 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 401.0
PYH1_k127_548842_2 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 400.0
PYH1_k127_548842_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000009963 156.0
PYH1_k127_5581112_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008538 285.0
PYH1_k127_5604667_0 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 417.0
PYH1_k127_5604667_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 308.0
PYH1_k127_5604667_2 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003835 257.0
PYH1_k127_5604667_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000335 261.0
PYH1_k127_5604667_4 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000007242 214.0
PYH1_k127_5604667_5 regulation of translation K03530 - - 0.0000000000000000000000000000000000009007 141.0
PYH1_k127_5604667_6 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000002969 133.0
PYH1_k127_5604667_7 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000005598 108.0
PYH1_k127_5604667_8 - - - - 0.00000004816 58.0
PYH1_k127_5632891_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.253e-236 739.0
PYH1_k127_5632891_1 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000001641 83.0
PYH1_k127_5637297_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.056e-201 646.0
PYH1_k127_5669386_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 343.0
PYH1_k127_56757_0 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 362.0
PYH1_k127_56757_1 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
PYH1_k127_56757_2 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000000005177 215.0
PYH1_k127_56757_3 CHASE - - - 0.0000004862 60.0
PYH1_k127_56757_4 Methyltransferase type 11 - - - 0.000003151 52.0
PYH1_k127_56757_5 PilZ domain - - - 0.000952 47.0
PYH1_k127_575780_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 409.0
PYH1_k127_575780_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 298.0
PYH1_k127_575780_2 PFAM methyltransferase small K15460 - 2.1.1.223 0.00000000000000000000000000000000000000001078 166.0
PYH1_k127_575780_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000001137 128.0
PYH1_k127_575780_4 Protein of unknown function (DUF721) - - - 0.000000000000000000001964 99.0
PYH1_k127_5802201_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 5.855e-222 691.0
PYH1_k127_5802201_1 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 379.0
PYH1_k127_5802201_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 359.0
PYH1_k127_5802201_3 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000006401 243.0
PYH1_k127_5802201_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
PYH1_k127_5857657_0 Peptidase M50 K16922 - - 4.893e-226 721.0
PYH1_k127_5857657_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 508.0
PYH1_k127_5857657_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000004002 115.0
PYH1_k127_5857657_3 Protein of unknown function (DUF3467) - - - 0.00000004624 58.0
PYH1_k127_5893301_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 479.0
PYH1_k127_5893301_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 372.0
PYH1_k127_5893301_2 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000000000000000000000001753 217.0
PYH1_k127_5893301_3 Ion channel - - - 0.00000000000000000000000000000134 131.0
PYH1_k127_5913689_0 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000002524 221.0
PYH1_k127_5913689_1 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000009156 139.0
PYH1_k127_5913689_2 - - - - 0.000000000000000006061 88.0
PYH1_k127_5913689_3 - - - - 0.00000000000000874 79.0
PYH1_k127_5921538_0 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 428.0
PYH1_k127_5921538_1 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000006589 151.0
PYH1_k127_5937512_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 287.0
PYH1_k127_5937512_1 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000006147 254.0
PYH1_k127_5937512_2 PBP superfamily domain K05772 - - 0.000000000000000000000000000004492 119.0
PYH1_k127_5939478_0 Predicted membrane protein (DUF2318) - - - 0.00000000000000008739 86.0
PYH1_k127_5939478_1 - - - - 0.00000006123 56.0
PYH1_k127_5939478_2 SurA N-terminal domain K03771 - 5.2.1.8 0.000005372 58.0
PYH1_k127_5967352_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001288 272.0
PYH1_k127_5967352_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001661 260.0
PYH1_k127_5967352_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000002372 254.0
PYH1_k127_5967352_3 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000000000000000000001131 232.0
PYH1_k127_5967352_4 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000001834 197.0
PYH1_k127_5967352_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000001868 206.0
PYH1_k127_5967352_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000007632 116.0
PYH1_k127_5967352_7 Methionine biosynthesis protein MetW - - - 0.000000000000000000000008135 111.0
PYH1_k127_5967352_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000005849 93.0
PYH1_k127_5977794_0 SMART Nucleotide binding protein, PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 553.0
PYH1_k127_5977794_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 327.0
PYH1_k127_5977794_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000975 147.0
PYH1_k127_5977794_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000003118 121.0
PYH1_k127_6031903_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008375 269.0
PYH1_k127_6031903_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000003783 267.0
PYH1_k127_6031903_2 cellulase activity - - - 0.0000000000000000000000000001096 131.0
PYH1_k127_6041841_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 4.81e-221 711.0
PYH1_k127_6041841_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 447.0
PYH1_k127_6041841_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000002235 226.0
PYH1_k127_6041841_3 RNA recognition motif - - - 0.00000000000000000000000001189 113.0
PYH1_k127_6041841_4 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001163 64.0
PYH1_k127_6052475_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 1.776e-204 656.0
PYH1_k127_6052475_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 376.0
PYH1_k127_6052475_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000009548 213.0
PYH1_k127_6052475_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000005944 172.0
PYH1_k127_6052475_4 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000001117 92.0
PYH1_k127_6059802_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.382e-251 786.0
PYH1_k127_6059802_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 377.0
PYH1_k127_6059802_2 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 327.0
PYH1_k127_6059802_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000007462 117.0
PYH1_k127_6059802_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000005648 111.0
PYH1_k127_6059802_5 cytochrome c5 - - - 0.00000000000000000000004642 102.0
PYH1_k127_6059802_6 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000005838 106.0
PYH1_k127_6059802_7 ATP synthesis coupled proton transport K02109 - - 0.00000000000002654 79.0
PYH1_k127_6059802_8 Uncharacterized integral membrane protein (DUF2301) - - - 0.000000001202 66.0
PYH1_k127_6068496_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 529.0
PYH1_k127_6068496_1 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000001145 229.0
PYH1_k127_6068496_2 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000001689 219.0
PYH1_k127_6068496_4 - - - - 0.000000000000008553 80.0
PYH1_k127_607097_1 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000008463 162.0
PYH1_k127_607097_3 protein conserved in bacteria K09796 - - 0.0000000000002346 76.0
PYH1_k127_607097_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00009953 48.0
PYH1_k127_6072143_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 430.0
PYH1_k127_6072143_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000009707 242.0
PYH1_k127_6072143_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000004628 232.0
PYH1_k127_6072143_3 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000003425 209.0
PYH1_k127_6072143_4 ATPase involved in DNA repair - - - 0.00000000001205 78.0
PYH1_k127_6072143_5 PFAM PSP1 domain protein - - - 0.00001942 54.0
PYH1_k127_6072990_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 353.0
PYH1_k127_6072990_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000002131 67.0
PYH1_k127_6072990_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000002223 60.0
PYH1_k127_6072990_3 mRNA binding - - - 0.000000009896 60.0
PYH1_k127_6072990_4 helix_turn_helix, mercury resistance - - - 0.0000005811 60.0
PYH1_k127_6092351_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 312.0
PYH1_k127_6092351_1 purine nucleobase transmembrane transporter activity K06901 - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
PYH1_k127_6092351_2 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000001232 149.0
PYH1_k127_6092351_3 GYD domain - - - 0.00000000000000000000000000000000000001167 149.0
PYH1_k127_6092351_4 Protein of unknown function (DUF3187) - - - 0.00000000000000000000004497 111.0
PYH1_k127_6092351_5 Predicted RNA-binding protein - - - 0.00000001312 58.0
PYH1_k127_6094240_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 336.0
PYH1_k127_6094240_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
PYH1_k127_6094240_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000006877 230.0
PYH1_k127_6094240_3 Universal stress protein - - - 0.0000000000000000000000000000000000001336 147.0
PYH1_k127_6094240_4 mttA/Hcf106 family K03116 - - 0.000000000009172 68.0
PYH1_k127_6116433_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005861 250.0
PYH1_k127_6116433_1 Elongator protein 3, MiaB family, Radical SAM K02585 - - 0.0000000000000000000000000002724 124.0
PYH1_k127_6138770_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 458.0
PYH1_k127_6138770_1 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 310.0
PYH1_k127_6138770_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006893 283.0
PYH1_k127_6138770_3 Histidine kinase - - - 0.00001519 55.0
PYH1_k127_6165488_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 492.0
PYH1_k127_6165488_1 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 457.0
PYH1_k127_6165488_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 327.0
PYH1_k127_6165488_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 302.0
PYH1_k127_6165488_4 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001278 244.0
PYH1_k127_6165488_5 Fe-S cluster domain protein - - - 0.000000000000000003941 91.0
PYH1_k127_6165488_6 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - GO:0008150,GO:0008152,GO:0009058,GO:0042618,GO:0042619,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000004859 68.0
PYH1_k127_6168778_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 424.0
PYH1_k127_6168778_1 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000002136 184.0
PYH1_k127_6168778_2 PFAM cobalbumin biosynthesis K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000005045 181.0
PYH1_k127_6168778_3 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000001417 158.0
PYH1_k127_6168778_4 Thioredoxin-like - - - 0.0000000000000000000000000000000000104 145.0
PYH1_k127_6168778_5 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.00000000000000000000000000935 128.0
PYH1_k127_6168778_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000008445 79.0
PYH1_k127_6168778_7 4Fe-4S binding domain - - - 0.000000000001037 70.0
PYH1_k127_6168778_8 - - - - 0.0001742 47.0
PYH1_k127_6184998_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 312.0
PYH1_k127_6184998_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 288.0
PYH1_k127_6184998_2 NosL - - - 0.0000000000000000000000000000000002903 133.0
PYH1_k127_6184998_3 Predicted membrane protein (DUF2318) - - - 0.00000000002139 72.0
PYH1_k127_6184998_4 Protein of unknown function (DUF2892) - - - 0.0000000004355 67.0
PYH1_k127_6195621_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.414e-212 679.0
PYH1_k127_6195621_1 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 351.0
PYH1_k127_6195621_10 Domain of unknown function (DUF4388) - - - 0.00001218 54.0
PYH1_k127_6195621_2 - - - - 0.0000000000000000000000000000000000000000000000000000000008351 215.0
PYH1_k127_6195621_3 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000006101 207.0
PYH1_k127_6195621_4 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000002031 187.0
PYH1_k127_6195621_5 FecR protein - - - 0.0000000000000000000000000000000000000000000004097 176.0
PYH1_k127_6195621_6 response regulator receiver K02481 - - 0.000000000000000000000005619 106.0
PYH1_k127_6195621_7 Transglutaminase-like superfamily - - - 0.000000000000000000001906 109.0
PYH1_k127_6195621_8 Domain of unknown function (DUF4416) - - - 0.00000000000000000003041 93.0
PYH1_k127_6195621_9 - - - - 0.0000000000005222 69.0
PYH1_k127_622831_0 Sulfatase - - - 1.076e-233 740.0
PYH1_k127_622831_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.008e-222 705.0
PYH1_k127_622831_10 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001608 188.0
PYH1_k127_622831_11 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 3.5.1.44 0.000000000000000000000000000000000000000000000000494 181.0
PYH1_k127_622831_12 Twitching motility two-component system response regulator PilH K02658 - - 0.0000000000000000000000000000000000000000446 154.0
PYH1_k127_622831_13 Smr domain - - - 0.000000000000000000000000000000000000002781 155.0
PYH1_k127_622831_14 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000001291 145.0
PYH1_k127_622831_15 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000003027 136.0
PYH1_k127_622831_16 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000008724 136.0
PYH1_k127_622831_17 - - - - 0.000000000000000000002895 96.0
PYH1_k127_622831_18 chemotaxis K03408 - - 0.0000000000000002848 85.0
PYH1_k127_622831_19 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000004401 69.0
PYH1_k127_622831_2 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 565.0
PYH1_k127_622831_3 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 510.0
PYH1_k127_622831_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 404.0
PYH1_k127_622831_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 293.0
PYH1_k127_622831_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002384 240.0
PYH1_k127_622831_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000003154 225.0
PYH1_k127_622831_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000004485 202.0
PYH1_k127_622831_9 response regulator K02658 - - 0.00000000000000000000000000000000000000000000000000001067 205.0
PYH1_k127_6238069_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 599.0
PYH1_k127_6238069_1 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 510.0
PYH1_k127_6238069_10 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000001988 106.0
PYH1_k127_6238069_11 electron transfer activity K05337,K17247 - - 0.00000000000000000001267 93.0
PYH1_k127_6238069_12 Cytochrome c - - - 0.0000001733 57.0
PYH1_k127_6238069_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 505.0
PYH1_k127_6238069_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 444.0
PYH1_k127_6238069_4 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 374.0
PYH1_k127_6238069_5 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 328.0
PYH1_k127_6238069_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 303.0
PYH1_k127_6238069_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000007714 262.0
PYH1_k127_6238069_8 translation initiation factor activity - - - 0.00000000000000000000000000000004725 135.0
PYH1_k127_6238069_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000001947 113.0
PYH1_k127_6241761_0 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 350.0
PYH1_k127_6241761_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008554 261.0
PYH1_k127_6241761_2 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0000000000000001973 80.0
PYH1_k127_6276051_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 334.0
PYH1_k127_6276051_1 Domain of unknown function (DUF4145) - - - 0.000000000000000000000000000000000000000000000004036 181.0
PYH1_k127_6276051_2 Tetratricopeptide repeat - - - 0.00000001698 66.0
PYH1_k127_6276051_3 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000007769 58.0
PYH1_k127_6339541_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000001247 161.0
PYH1_k127_6339541_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000002922 139.0
PYH1_k127_6339541_2 - - - - 0.00000000000000000000000000000001161 134.0
PYH1_k127_6339541_3 - - - - 0.0000000000000000005895 94.0
PYH1_k127_6339541_4 - - - - 0.00000002884 63.0
PYH1_k127_6350440_0 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001526 248.0
PYH1_k127_6350440_1 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009211 252.0
PYH1_k127_6350440_2 proline betaine transporter - - - 0.0000000000000000000000000000000000000000000000000000000000006468 215.0
PYH1_k127_6350440_3 BadF BadG BcrA BcrD - - - 0.000000000004459 72.0
PYH1_k127_6350440_4 phosphorelay signal transduction system - - - 0.000000003855 66.0
PYH1_k127_6364371_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000001679 269.0
PYH1_k127_6364371_2 ABC1 family - - - 0.000000309 55.0
PYH1_k127_6413950_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 351.0
PYH1_k127_6413950_1 ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 306.0
PYH1_k127_6413950_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 267.0
PYH1_k127_6413950_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005475 266.0
PYH1_k127_6413950_4 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000007444 236.0
PYH1_k127_6413950_5 NOG31153 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000002017 222.0
PYH1_k127_6413950_6 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000001021 122.0
PYH1_k127_6413950_7 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000001672 116.0
PYH1_k127_6413950_9 electron transfer activity K05337,K17247 - - 0.0000000005569 61.0
PYH1_k127_643710_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 468.0
PYH1_k127_643710_1 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009173 257.0
PYH1_k127_643710_2 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 256.0
PYH1_k127_643710_3 Rhodanese domain protein - - - 0.00000000000000000000000005123 118.0
PYH1_k127_6444625_0 Capsule polysaccharide K07266 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 379.0
PYH1_k127_6444625_2 capsule polysaccharide K07265 - - 0.000000000000000000000000000000000012 138.0
PYH1_k127_6504116_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1211.0
PYH1_k127_6504116_1 nitric oxide dioxygenase activity K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 491.0
PYH1_k127_6504116_2 Phosphate-starvation-inducible E - - - 0.0000000000000005081 83.0
PYH1_k127_6546551_0 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 565.0
PYH1_k127_6546551_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000007891 134.0
PYH1_k127_6546551_2 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000001198 117.0
PYH1_k127_6546551_3 - - - - 0.000000000000000000004375 103.0
PYH1_k127_6554244_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 388.0
PYH1_k127_6554244_1 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 331.0
PYH1_k127_6554244_2 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 321.0
PYH1_k127_6554244_3 Capsule polysaccharide K07266 - - 0.0000000000000000000000000000000000000000000000000000000000000002641 228.0
PYH1_k127_6570588_0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000001178 108.0
PYH1_k127_6570588_1 Appr-1'-p processing enzyme - - - 0.000000000000000000003607 95.0
PYH1_k127_6587254_0 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 524.0
PYH1_k127_6587254_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
PYH1_k127_6587254_2 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000002109 173.0
PYH1_k127_6587254_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000011 145.0
PYH1_k127_6620195_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 6.825e-213 668.0
PYH1_k127_6620195_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 375.0
PYH1_k127_6620195_2 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000001424 162.0
PYH1_k127_6640066_0 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 396.0
PYH1_k127_6640066_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 380.0
PYH1_k127_6640066_2 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
PYH1_k127_6640066_3 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000003999 205.0
PYH1_k127_6640066_4 membrane K00389 - - 0.0000000000000000000000000000000000000000005867 161.0
PYH1_k127_6640066_5 - - - - 0.00000000000000000000000000000000000016 151.0
PYH1_k127_6640066_6 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000001596 127.0
PYH1_k127_6640066_7 - - - - 0.0000000008313 66.0
PYH1_k127_6699192_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 582.0
PYH1_k127_6699192_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 395.0
PYH1_k127_6699192_2 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 303.0
PYH1_k127_6699192_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000002435 264.0
PYH1_k127_6699192_4 DNA topoisomerase II activity K02470,K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 5.99.1.3 0.0000000000000000000000000000000000000000000000000007566 186.0
PYH1_k127_6699192_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000001602 96.0
PYH1_k127_6730306_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1151.0
PYH1_k127_6730306_1 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 548.0
PYH1_k127_6730306_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 361.0
PYH1_k127_6730306_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001183 183.0
PYH1_k127_6730306_4 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000003664 132.0
PYH1_k127_6730306_5 lyase activity - - - 0.00000000000000002238 87.0
PYH1_k127_6730306_6 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000003117 66.0
PYH1_k127_6745052_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000001503 193.0
PYH1_k127_6745052_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000004173 181.0
PYH1_k127_6745052_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000004694 175.0
PYH1_k127_6745052_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000007011 154.0
PYH1_k127_6745052_4 TIGRFAM transcriptional regulator, AbrB family - - - 0.0000000000000000136 84.0
PYH1_k127_6745052_5 PFAM Rubrerythrin - - - 0.0000000000000002747 84.0
PYH1_k127_675777_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 3.641e-197 629.0
PYH1_k127_675777_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 351.0
PYH1_k127_675777_2 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
PYH1_k127_675777_3 PFAM YaeQ family protein - - - 0.00000000000000000000000000000000000000000000000000003004 189.0
PYH1_k127_6768683_0 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
PYH1_k127_6768683_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000009803 178.0
PYH1_k127_6768683_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000005116 119.0
PYH1_k127_6768683_3 Dolichol kinase - - - 0.00000000000006003 79.0
PYH1_k127_6768683_4 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00005332 52.0
PYH1_k127_6772379_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000005412 156.0
PYH1_k127_6772379_2 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000000001794 123.0
PYH1_k127_6781625_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 529.0
PYH1_k127_6781625_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 289.0
PYH1_k127_6781625_2 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006373 271.0
PYH1_k127_6781625_3 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000003692 182.0
PYH1_k127_6781625_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000006704 158.0
PYH1_k127_6781625_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000006272 145.0
PYH1_k127_6781625_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000001958 129.0
PYH1_k127_6781625_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000306 130.0
PYH1_k127_6785464_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.917e-305 943.0
PYH1_k127_6785464_1 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 491.0
PYH1_k127_6785464_10 - - - - 0.0000002782 59.0
PYH1_k127_6785464_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 466.0
PYH1_k127_6785464_3 PFAM MltA K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 342.0
PYH1_k127_6785464_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000005451 254.0
PYH1_k127_6785464_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000001371 212.0
PYH1_k127_6785464_6 - - - - 0.000000000000000000000000000000129 132.0
PYH1_k127_6785464_7 PFAM thiamineS protein - - - 0.00000000004012 66.0
PYH1_k127_6790720_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 399.0
PYH1_k127_6790720_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000002985 165.0
PYH1_k127_6790720_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000009426 129.0
PYH1_k127_6790765_0 Two component regulator three Y domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 386.0
PYH1_k127_6790765_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006431 231.0
PYH1_k127_6790765_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000036 191.0
PYH1_k127_6790765_3 diguanylate cyclase - - - 0.00000000000004013 82.0
PYH1_k127_6798707_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2055.0
PYH1_k127_6798707_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1051.0
PYH1_k127_6798707_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 442.0
PYH1_k127_6798707_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000003048 229.0
PYH1_k127_6798707_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002665 217.0
PYH1_k127_6798707_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000004563 108.0
PYH1_k127_6800822_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 488.0
PYH1_k127_6800822_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002334 289.0
PYH1_k127_6804560_0 General secretory system II, protein E domain protein K02652 - - 9.614e-219 694.0
PYH1_k127_6804560_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001262 283.0
PYH1_k127_6804560_2 Large extracellular alpha-helical protein - - - 0.000000000000000000000143 114.0
PYH1_k127_6815248_0 PAS domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 525.0
PYH1_k127_6815248_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006929 252.0
PYH1_k127_6815248_2 Lysin motif - - - 0.0000000000000000000000000000128 133.0
PYH1_k127_6815248_3 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000004204 117.0
PYH1_k127_6815248_4 Rhodanese Homology Domain - - - 0.00000000000000001032 88.0
PYH1_k127_6815248_5 - - - - 0.0000000000000135 73.0
PYH1_k127_685623_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 312.0
PYH1_k127_685623_1 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001796 254.0
PYH1_k127_685623_2 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000004092 228.0
PYH1_k127_685623_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000002487 133.0
PYH1_k127_6869635_0 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001455 268.0
PYH1_k127_6869635_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000005054 189.0
PYH1_k127_6869635_2 - - - - 0.0000000000000000000000006362 105.0
PYH1_k127_6869635_3 radical SAM domain protein - - - 0.00000000000000009005 81.0
PYH1_k127_6874829_0 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
PYH1_k127_6874829_1 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000006255 231.0
PYH1_k127_6874829_2 OsmC-like protein K07397 - - 0.0000000000000000000001164 107.0
PYH1_k127_6876329_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 482.0
PYH1_k127_6876329_1 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 338.0
PYH1_k127_6876329_3 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000001135 120.0
PYH1_k127_6876329_5 NosL - - - 0.0000002207 53.0
PYH1_k127_6877310_0 ABC transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 327.0
PYH1_k127_6877310_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
PYH1_k127_6877310_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000004181 158.0
PYH1_k127_6877310_3 PAS fold - - - 0.0000000000000000001204 102.0
PYH1_k127_6881521_0 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 7.292e-204 645.0
PYH1_k127_6881521_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008607 269.0
PYH1_k127_6881521_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000414 170.0
PYH1_k127_6883268_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1511.0
PYH1_k127_6883268_1 mannitol 2-dehydrogenase activity K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 555.0
PYH1_k127_6883268_10 PEP-CTERM motif - - - 0.00000000000000003093 96.0
PYH1_k127_6883268_11 Autoinducer binding domain - - - 0.000000000001358 70.0
PYH1_k127_6883268_12 Ceramidase - - - 0.000006251 51.0
PYH1_k127_6883268_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 443.0
PYH1_k127_6883268_3 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002645 291.0
PYH1_k127_6883268_4 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006486 259.0
PYH1_k127_6883268_5 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003773 250.0
PYH1_k127_6883268_6 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000008604 165.0
PYH1_k127_6883268_7 Ceramidase - - - 0.0000000000000000000000000000000000000000001314 166.0
PYH1_k127_6883268_8 His Kinase A (phosphoacceptor) domain K13533 - 2.7.13.3 0.00000000000000000000000000000000000000002309 169.0
PYH1_k127_6883268_9 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000004227 154.0
PYH1_k127_6900825_0 COG0058 Glucan phosphorylase - - - 2.479e-255 799.0
PYH1_k127_6900825_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000652 230.0
PYH1_k127_6900825_2 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000002089 160.0
PYH1_k127_6913184_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1204.0
PYH1_k127_6913184_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 609.0
PYH1_k127_6913184_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000003708 243.0
PYH1_k127_6913184_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000001795 164.0
PYH1_k127_6913184_4 cellulase activity - - - 0.000000000000000000003659 106.0
PYH1_k127_6913184_6 polyketide synthase - - - 0.0006871 51.0
PYH1_k127_6923703_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 583.0
PYH1_k127_6923703_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 401.0
PYH1_k127_6923703_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 382.0
PYH1_k127_6923703_3 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 335.0
PYH1_k127_6923703_4 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000377 198.0
PYH1_k127_6923703_5 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000004794 198.0
PYH1_k127_6923703_6 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000002468 121.0
PYH1_k127_6923703_7 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000007761 78.0
PYH1_k127_6932654_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 509.0
PYH1_k127_6932654_1 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 246.0
PYH1_k127_6932654_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000001628 229.0
PYH1_k127_6932654_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000001038 179.0
PYH1_k127_6932654_4 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000002619 145.0
PYH1_k127_6932654_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.0000000004012 70.0
PYH1_k127_6933570_0 AMP-binding enzyme C-terminal domain K00666 - - 1.216e-262 819.0
PYH1_k127_6933570_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 349.0
PYH1_k127_6933570_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000004363 77.0
PYH1_k127_6933570_3 peroxiredoxin activity K03564 - 1.11.1.15 0.0003761 47.0
PYH1_k127_6954179_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 346.0
PYH1_k127_6954179_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
PYH1_k127_6954179_2 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000001735 203.0
PYH1_k127_6954179_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000021 184.0
PYH1_k127_6954179_4 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000002651 185.0
PYH1_k127_6985479_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 379.0
PYH1_k127_6985479_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 346.0
PYH1_k127_6985479_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000595 124.0
PYH1_k127_7023754_0 PFAM Tetratricopeptide repeat - - - 7.465e-198 635.0
PYH1_k127_7023754_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 445.0
PYH1_k127_7023754_2 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 296.0
PYH1_k127_7023754_3 integral membrane protein - - - 0.00000000000008357 79.0
PYH1_k127_7044035_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 457.0
PYH1_k127_7044035_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 393.0
PYH1_k127_7050241_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 519.0
PYH1_k127_7050241_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000001472 154.0
PYH1_k127_7050241_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000001035 129.0
PYH1_k127_7054056_0 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 415.0
PYH1_k127_7054056_1 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000002224 145.0
PYH1_k127_7078324_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 387.0
PYH1_k127_7078324_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 379.0
PYH1_k127_7078324_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 315.0
PYH1_k127_7157453_0 aspartate-tRNA(Asn) ligase activity K01876 - 6.1.1.12 1.949e-248 779.0
PYH1_k127_7157453_1 Hemerythrin K07216 - - 0.0000000001416 67.0
PYH1_k127_7185384_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 406.0
PYH1_k127_7185384_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004661 268.0
PYH1_k127_7185384_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000126 225.0
PYH1_k127_7185384_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000004839 190.0
PYH1_k127_7185384_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000002221 181.0
PYH1_k127_7185384_5 Belongs to the UPF0250 family K09158 - - 0.000000000000000015 85.0
PYH1_k127_7185384_6 PD-(D/E)XK nuclease superfamily - - - 0.00000005281 59.0
PYH1_k127_7185384_7 PD-(D/E)XK nuclease superfamily - - - 0.000003079 51.0
PYH1_k127_7194031_0 Pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 496.0
PYH1_k127_7194031_1 protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000001015 195.0
PYH1_k127_7194031_2 SNARE associated Golgi protein - - - 0.000000000000000000000007913 110.0
PYH1_k127_7195131_0 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 536.0
PYH1_k127_7195131_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002434 244.0
PYH1_k127_7195131_2 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000007631 196.0
PYH1_k127_7195131_3 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000005352 132.0
PYH1_k127_7327872_0 Major facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 376.0
PYH1_k127_7327872_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000001588 174.0
PYH1_k127_7327872_2 - - - - 0.000000000000004438 83.0
PYH1_k127_7346156_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 362.0
PYH1_k127_7346156_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
PYH1_k127_7346156_2 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000008109 176.0
PYH1_k127_7346156_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000005575 145.0
PYH1_k127_7346156_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000003 102.0
PYH1_k127_7346156_5 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.000000000001083 78.0
PYH1_k127_7346156_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00002803 55.0
PYH1_k127_7363447_0 Tripartite tricarboxylate transporter TctA family K07793 - - 8.185e-242 758.0
PYH1_k127_7363447_1 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 332.0
PYH1_k127_7363447_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 307.0
PYH1_k127_7363447_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 307.0
PYH1_k127_7363447_4 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000005885 169.0
PYH1_k127_7363447_5 Immunity protein 35 - - - 0.00000000000000000000000000000000000005743 144.0
PYH1_k127_7363447_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000005194 105.0
PYH1_k127_7363447_7 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000102 81.0
PYH1_k127_7363447_8 COG4670 Acyl CoA acetate 3-ketoacid CoA transferase K13929 - 2.3.1.187 0.0000009973 51.0
PYH1_k127_7368818_0 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000002682 142.0
PYH1_k127_7368818_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000005291 85.0
PYH1_k127_7368818_2 TIGRFAM Outer membrane protein K13735,K20276 - - 0.0000002959 64.0
PYH1_k127_7398546_0 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 441.0
PYH1_k127_7398546_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000003545 230.0
PYH1_k127_7398546_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000006961 176.0
PYH1_k127_7424_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 612.0
PYH1_k127_7424_1 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000349 252.0
PYH1_k127_7424_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000001406 93.0
PYH1_k127_7424_3 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000002788 90.0
PYH1_k127_7486713_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.748e-196 627.0
PYH1_k127_7486713_1 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 385.0
PYH1_k127_7486713_2 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000001687 240.0
PYH1_k127_7486713_3 YbbR-like protein - - - 0.0000000000000000000000000000000005408 139.0
PYH1_k127_7486713_4 - - - - 0.0000000000000003276 84.0
PYH1_k127_7486713_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000003252 56.0
PYH1_k127_7552974_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 572.0
PYH1_k127_7552974_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 465.0
PYH1_k127_7552974_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 394.0
PYH1_k127_7552974_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
PYH1_k127_7552974_4 - K00712 - 2.4.1.52 0.0000000000000000000000000000000000004392 154.0
PYH1_k127_7552974_5 DNA ligase K01971 - 6.5.1.1 0.000000000000004894 75.0
PYH1_k127_7552974_6 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000005097 53.0
PYH1_k127_7552974_7 - - - - 0.0000007086 54.0
PYH1_k127_7582380_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.529e-315 985.0
PYH1_k127_7582380_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.75e-298 935.0
PYH1_k127_7582380_10 peptidyl-tyrosine sulfation - - - 0.000000000005563 76.0
PYH1_k127_7582380_12 Recombinase zinc beta ribbon domain - - - 0.0002309 48.0
PYH1_k127_7582380_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 557.0
PYH1_k127_7582380_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 444.0
PYH1_k127_7582380_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 386.0
PYH1_k127_7582380_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.000000000000000000000000000000000000000000000003333 179.0
PYH1_k127_7582380_6 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000008597 155.0
PYH1_k127_7582380_7 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000734 151.0
PYH1_k127_7582380_8 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000005482 131.0
PYH1_k127_7582380_9 Tetratricopeptide repeat - - - 0.000000000004975 75.0
PYH1_k127_759871_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 336.0
PYH1_k127_759871_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 308.0
PYH1_k127_759871_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 306.0
PYH1_k127_759871_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 287.0
PYH1_k127_759871_4 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002737 250.0
PYH1_k127_759871_5 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000003109 152.0
PYH1_k127_759871_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.000000000000342 71.0
PYH1_k127_7622220_0 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 517.0
PYH1_k127_7622220_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 438.0
PYH1_k127_7622220_2 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000000000004255 78.0
PYH1_k127_7648105_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 601.0
PYH1_k127_7648105_1 purine nucleobase transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 411.0
PYH1_k127_7648105_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 353.0
PYH1_k127_7648105_3 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 315.0
PYH1_k127_7648105_4 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000001366 222.0
PYH1_k127_7648105_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
PYH1_k127_7676407_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 486.0
PYH1_k127_7676407_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 350.0
PYH1_k127_7685279_1 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 325.0
PYH1_k127_7697894_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 584.0
PYH1_k127_7697894_1 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
PYH1_k127_7697894_2 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 410.0
PYH1_k127_7697894_3 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 370.0
PYH1_k127_7697894_4 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 362.0
PYH1_k127_7697894_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000005303 223.0
PYH1_k127_7697894_6 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000006033 192.0
PYH1_k127_7697894_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000003254 186.0
PYH1_k127_7697894_8 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000004359 65.0
PYH1_k127_7699905_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1108.0
PYH1_k127_7699905_1 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
PYH1_k127_7699905_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 295.0
PYH1_k127_7699905_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006635 284.0
PYH1_k127_7699905_4 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005976 272.0
PYH1_k127_7699905_5 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009377 242.0
PYH1_k127_7699905_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000002076 210.0
PYH1_k127_7699905_7 NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000003248 123.0
PYH1_k127_7699905_8 Bacterial protein of unknown function (DUF922) - - - 0.00000000000000000000766 100.0
PYH1_k127_7706792_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 407.0
PYH1_k127_7706792_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 325.0
PYH1_k127_7706792_10 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000001264 143.0
PYH1_k127_7706792_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003364 66.0
PYH1_k127_7706792_12 Putative diguanylate phosphodiesterase - - - 0.000000008325 66.0
PYH1_k127_7706792_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 301.0
PYH1_k127_7706792_3 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 313.0
PYH1_k127_7706792_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000003773 245.0
PYH1_k127_7706792_5 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000001995 224.0
PYH1_k127_7706792_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003057 198.0
PYH1_k127_7706792_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000002608 208.0
PYH1_k127_7706792_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000001678 171.0
PYH1_k127_7706792_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000004303 140.0
PYH1_k127_7711082_0 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 552.0
PYH1_k127_7711082_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 328.0
PYH1_k127_7711082_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000395 296.0
PYH1_k127_7711082_3 - - - - 0.000000000000006966 80.0
PYH1_k127_7720547_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 338.0
PYH1_k127_7720547_1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000007756 234.0
PYH1_k127_7720547_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000022 211.0
PYH1_k127_7720547_3 Major facilitator Superfamily - - - 0.00001595 57.0
PYH1_k127_7748479_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 477.0
PYH1_k127_7748479_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 445.0
PYH1_k127_7748479_2 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 434.0
PYH1_k127_7748479_3 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 429.0
PYH1_k127_7748479_4 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 377.0
PYH1_k127_7748479_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004394 239.0
PYH1_k127_7748479_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000005534 223.0
PYH1_k127_7748479_7 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000329 183.0
PYH1_k127_7748479_8 RF-1 domain - - - 0.00000000000000000000000008983 113.0
PYH1_k127_7776539_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 553.0
PYH1_k127_7776539_1 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000001066 223.0
PYH1_k127_7776539_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 GO:0008150,GO:0008219,GO:0009987 - 0.00000000000000000000000000000005526 127.0
PYH1_k127_7776539_3 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000001141 126.0
PYH1_k127_7776539_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000004082 104.0
PYH1_k127_7776539_5 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000001318 67.0
PYH1_k127_7776539_6 SpoIIAA-like - - - 0.000000009546 57.0
PYH1_k127_7782764_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 493.0
PYH1_k127_7782764_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 410.0
PYH1_k127_7782764_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 371.0
PYH1_k127_7782764_3 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 335.0
PYH1_k127_7782764_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
PYH1_k127_7783568_0 PFAM ABC transporter related K06020 - 3.6.3.25 1.015e-300 928.0
PYH1_k127_7783568_1 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 318.0
PYH1_k127_7783568_2 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000004433 183.0
PYH1_k127_7783568_3 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000128 120.0
PYH1_k127_7783568_4 Cytochrome b/b6/petB K03887 - - 0.000000000000000001995 86.0
PYH1_k127_7787955_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 296.0
PYH1_k127_7787955_1 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000001702 276.0
PYH1_k127_7787955_2 Protein of unknown function DUF116 - - - 0.000000000000000001117 96.0
PYH1_k127_7787955_3 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000001905 90.0
PYH1_k127_7803900_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000001901 196.0
PYH1_k127_7803900_1 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000001905 162.0
PYH1_k127_7803900_2 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000001463 128.0
PYH1_k127_7803900_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000788 84.0
PYH1_k127_7806895_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.197e-202 637.0
PYH1_k127_7806895_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 488.0
PYH1_k127_7806895_2 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 351.0
PYH1_k127_7806895_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009648 265.0
PYH1_k127_7849739_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 518.0
PYH1_k127_7849739_1 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 505.0
PYH1_k127_7849739_2 - - - - 0.00000000000000000000000008522 116.0
PYH1_k127_7849739_3 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000001574 100.0
PYH1_k127_7849739_4 - - - - 0.000000000007635 68.0
PYH1_k127_7860684_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 439.0
PYH1_k127_7860684_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000132 102.0
PYH1_k127_7862977_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.991e-205 653.0
PYH1_k127_7862977_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 295.0
PYH1_k127_7862977_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009767 278.0
PYH1_k127_7862977_3 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
PYH1_k127_7862977_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000004964 223.0
PYH1_k127_7862977_5 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000131 117.0
PYH1_k127_7862977_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000679 78.0
PYH1_k127_7862977_7 Histidine kinase - - - 0.000009026 49.0
PYH1_k127_7905397_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 514.0
PYH1_k127_7905397_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 347.0
PYH1_k127_7905397_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000007287 118.0
PYH1_k127_7905397_11 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000007355 124.0
PYH1_k127_7905397_12 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000003392 114.0
PYH1_k127_7905397_13 NifU-like domain - - - 0.00000000000000000000000152 106.0
PYH1_k127_7905397_14 GTP-binding GTPase Middle Region K03665 - - 0.0000000000000000000000191 105.0
PYH1_k127_7905397_15 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000001382 100.0
PYH1_k127_7905397_16 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000002757 87.0
PYH1_k127_7905397_17 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000738 72.0
PYH1_k127_7905397_2 PFAM glycosyl transferase, family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 317.0
PYH1_k127_7905397_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004518 280.0
PYH1_k127_7905397_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000003823 267.0
PYH1_k127_7905397_5 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
PYH1_k127_7905397_6 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000104 221.0
PYH1_k127_7905397_7 Smr domain - - - 0.00000000000000000000000000000000007713 141.0
PYH1_k127_7905397_8 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000001259 137.0
PYH1_k127_7905397_9 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000007054 130.0
PYH1_k127_7922430_0 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002303 292.0
PYH1_k127_7922430_1 Type II secretion system protein E K02243,K02652 - - 0.000000000000000000000005649 111.0
PYH1_k127_7922430_2 Protein of unknown function (DUF1573) - - - 0.00002496 49.0
PYH1_k127_7945123_0 transporter antisigma-factor antagonist STAS K03321 - - 2.079e-208 662.0
PYH1_k127_7945123_1 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 387.0
PYH1_k127_7945123_2 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000005445 204.0
PYH1_k127_7945123_4 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000367 153.0
PYH1_k127_7945123_5 Methyltransferase domain - - - 0.000000000000000000000000000000001447 139.0
PYH1_k127_7945123_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000004678 91.0
PYH1_k127_7945123_7 Tetratricopeptide repeat - - - 0.00000002474 62.0
PYH1_k127_7976326_0 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 475.0
PYH1_k127_7976326_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 439.0
PYH1_k127_7976326_2 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000002378 147.0
PYH1_k127_7976326_3 type II secretion system protein G K02456 - - 0.00000000000000000000000000000001018 135.0
PYH1_k127_7976326_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000174 93.0
PYH1_k127_7976326_5 Pilus assembly protein K02662 - - 0.000000000000000001288 97.0
PYH1_k127_7976326_6 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.0000000001415 71.0
PYH1_k127_7976326_7 Pilus assembly protein, PilO K02664 - - 0.0000000004468 68.0
PYH1_k127_7982774_0 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 382.0
PYH1_k127_7982774_1 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000003954 184.0
PYH1_k127_7982774_2 response regulator - - - 0.00000000002576 74.0
PYH1_k127_7982774_3 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000007276 64.0
PYH1_k127_7994676_0 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 416.0
PYH1_k127_7994676_1 Universal stress protein family K07090 - - 0.0000000000000000000000000000000004976 139.0
PYH1_k127_8016675_0 Telomere recombination K04656 - - 3.558e-226 729.0
PYH1_k127_8016675_1 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 432.0
PYH1_k127_8016675_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 378.0
PYH1_k127_8016675_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
PYH1_k127_8016675_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000282 153.0
PYH1_k127_8016675_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 0.00000000000000000000000000000000009748 133.0
PYH1_k127_8016675_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000106 96.0
PYH1_k127_8016675_7 carbon dioxide binding K04653,K04654 - - 0.0004406 49.0
PYH1_k127_8022755_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 488.0
PYH1_k127_8022755_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000001809 220.0
PYH1_k127_8022755_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000002515 137.0
PYH1_k127_8022755_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001148 95.0
PYH1_k127_806254_0 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000007893 186.0
PYH1_k127_806254_1 - - - - 0.0000000000000000000000000000000000000000000000002366 188.0
PYH1_k127_806254_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000002361 166.0
PYH1_k127_806254_3 Putative MetA-pathway of phenol degradation - - - 0.00003569 49.0
PYH1_k127_8093789_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 456.0
PYH1_k127_8093789_1 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 316.0
PYH1_k127_8093789_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000002757 213.0
PYH1_k127_8093789_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000002898 161.0
PYH1_k127_8093789_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000001943 124.0
PYH1_k127_8096400_0 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000000000000000000000000000006157 216.0
PYH1_k127_8096400_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000001512 207.0
PYH1_k127_8096400_2 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000003317 195.0
PYH1_k127_8096400_3 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000003819 159.0
PYH1_k127_8111375_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 292.0
PYH1_k127_8111375_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000002834 155.0
PYH1_k127_8111375_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000207 149.0
PYH1_k127_8111375_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000008468 117.0
PYH1_k127_8120109_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 307.0
PYH1_k127_8120109_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000001002 109.0
PYH1_k127_8127337_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 7.588e-248 770.0
PYH1_k127_8127337_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 482.0
PYH1_k127_8127337_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000004264 245.0
PYH1_k127_8127337_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000001039 59.0
PYH1_k127_8128945_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
PYH1_k127_8128945_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000002399 206.0
PYH1_k127_8128945_2 HD domain - - - 0.00000000000000000000000000000000000000000001044 178.0
PYH1_k127_8128945_4 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000761 63.0
PYH1_k127_8128945_5 sigma factor antagonist activity K04757 - 2.7.11.1 0.000001065 61.0
PYH1_k127_8178563_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 478.0
PYH1_k127_8178563_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
PYH1_k127_8178563_2 synthase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000009098 256.0
PYH1_k127_8253248_0 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000000002108 186.0
PYH1_k127_8253248_1 - - - - 0.0000000000000000000000000000000000000000002487 162.0
PYH1_k127_8253248_2 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000006993 118.0
PYH1_k127_8253248_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000004473 106.0
PYH1_k127_8253248_4 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.0000000000000000006117 92.0
PYH1_k127_8253248_5 PFAM Rubrerythrin - - - 0.000000000000000001016 86.0
PYH1_k127_8253248_6 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000001812 74.0
PYH1_k127_8253248_8 Flavin reductase like domain - - - 0.00000006159 60.0
PYH1_k127_8263746_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 486.0
PYH1_k127_8263746_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 390.0
PYH1_k127_8263746_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 385.0
PYH1_k127_8263746_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000004812 191.0
PYH1_k127_8298590_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 501.0
PYH1_k127_8298590_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000001679 154.0
PYH1_k127_8298590_2 Protein of unknown function (DUF1365) K09701 - - 0.00000000000001481 74.0
PYH1_k127_8322455_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 580.0
PYH1_k127_8322455_1 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 542.0
PYH1_k127_8322455_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 532.0
PYH1_k127_8322455_3 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000001181 161.0
PYH1_k127_843128_0 Thioredoxin-like - - - 0.00000000001761 68.0
PYH1_k127_843128_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000008566 67.0
PYH1_k127_867633_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 526.0
PYH1_k127_867633_1 Pfam Response regulator receiver - - - 0.000000000000000000000000000001944 125.0
PYH1_k127_867633_2 PAS fold - - - 0.000000000000000003933 98.0
PYH1_k127_868936_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 446.0
PYH1_k127_868936_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
PYH1_k127_868936_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000001755 182.0
PYH1_k127_889500_0 Pfam:CPSase_L_chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 506.0
PYH1_k127_939580_0 GXGXG motif - - - 3.958e-263 825.0
PYH1_k127_939580_1 L-glutamate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 317.0
PYH1_k127_953870_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 419.0
PYH1_k127_953870_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 398.0
PYH1_k127_953870_2 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 380.0
PYH1_k127_953870_3 ABC transporter C-terminal domain K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 367.0
PYH1_k127_953870_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 339.0
PYH1_k127_953870_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
PYH1_k127_953870_7 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000006367 119.0
PYH1_k127_959571_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 385.0
PYH1_k127_959571_1 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000002747 61.0
PYH1_k127_966495_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 597.0
PYH1_k127_966495_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 326.0
PYH1_k127_966495_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000578 125.0
PYH1_k127_966495_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000009128 126.0
PYH1_k127_966495_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000004325 115.0
PYH1_k127_966495_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001988 103.0
PYH1_k127_966495_14 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003992 76.0
PYH1_k127_966495_15 Ribosomal L29 protein K02904 - - 0.000000000000006837 76.0
PYH1_k127_966495_16 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0005102 43.0
PYH1_k127_966495_2 ribosomal L5P family C-terminus K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 262.0
PYH1_k127_966495_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000007938 227.0
PYH1_k127_966495_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002442 218.0
PYH1_k127_966495_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004984 200.0
PYH1_k127_966495_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000005053 203.0
PYH1_k127_966495_7 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003861 191.0
PYH1_k127_966495_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000004565 178.0
PYH1_k127_966495_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000001579 153.0
PYH1_k127_966567_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1138.0
PYH1_k127_966567_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.606e-250 797.0
PYH1_k127_966567_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000003921 213.0
PYH1_k127_966567_11 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000001013 205.0
PYH1_k127_966567_12 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000002163 141.0
PYH1_k127_966567_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000005939 135.0
PYH1_k127_966567_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000002968 124.0
PYH1_k127_966567_15 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.00000000000000000000000008402 114.0
PYH1_k127_966567_16 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000004671 108.0
PYH1_k127_966567_17 C-3'',4'' desaturase CrtD - - - 0.00000001369 67.0
PYH1_k127_966567_18 Hypothetical glycosyl hydrolase family 13 K11931 - - 0.0000008006 61.0
PYH1_k127_966567_19 unfolded protein binding K06142 - - 0.000001979 57.0
PYH1_k127_966567_2 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.041e-249 787.0
PYH1_k127_966567_3 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 510.0
PYH1_k127_966567_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 435.0
PYH1_k127_966567_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 332.0
PYH1_k127_966567_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 301.0
PYH1_k127_966567_7 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000009105 255.0
PYH1_k127_966567_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000107 241.0
PYH1_k127_966567_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000002511 246.0
PYH1_k127_976322_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
PYH1_k127_976322_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 323.0
PYH1_k127_976322_2 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
PYH1_k127_976322_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000001471 190.0
PYH1_k127_976322_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000464 136.0
PYH1_k127_976322_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000007783 128.0
PYH1_k127_976322_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000008377 120.0
PYH1_k127_976322_7 - - - - 0.000003301 55.0
PYH1_k127_981053_0 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000007093 194.0
PYH1_k127_981053_1 Nitroreductase family - - - 0.000000000000000000000000000000008974 134.0
PYH1_k127_9864_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 321.0
PYH1_k127_9864_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000001906 193.0
PYH1_k127_9864_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000005734 179.0
PYH1_k127_9864_3 E-Z type HEAT repeats - - - 0.00000000000004851 82.0
PYH1_k127_994913_0 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000005333 116.0
PYH1_k127_994913_1 Universal stress protein - - - 0.0001671 51.0
PYH1_k127_995022_0 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 599.0
PYH1_k127_995022_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 359.0