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Overview

ID MAG03136
Name PYH1_bin.26
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum BMS3Abin14
Class BMS3Abin14
Order BMS3Abin14
Family
Genus
Species
Assembly information
Completeness (%) 93.24
Contamination (%) 2.34
GC content (%) 66.0
N50 (bp) 18,896
Genome size (bp) 2,179,481

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1964

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1010728_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 551.0
PYH1_k127_1010728_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 527.0
PYH1_k127_1010728_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 390.0
PYH1_k127_1010728_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 325.0
PYH1_k127_1010728_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 307.0
PYH1_k127_1010728_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005282 260.0
PYH1_k127_1010728_6 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000001975 118.0
PYH1_k127_1010728_7 Uncharacterised ArCR, COG2043 - - - 0.000000004702 67.0
PYH1_k127_104969_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 571.0
PYH1_k127_104969_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 569.0
PYH1_k127_104969_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 364.0
PYH1_k127_104969_11 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 355.0
PYH1_k127_104969_12 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 340.0
PYH1_k127_104969_13 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 329.0
PYH1_k127_104969_14 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
PYH1_k127_104969_15 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 319.0
PYH1_k127_104969_16 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 335.0
PYH1_k127_104969_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 325.0
PYH1_k127_104969_18 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
PYH1_k127_104969_19 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
PYH1_k127_104969_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 566.0
PYH1_k127_104969_20 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 310.0
PYH1_k127_104969_21 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 299.0
PYH1_k127_104969_22 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 301.0
PYH1_k127_104969_23 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 280.0
PYH1_k127_104969_24 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 286.0
PYH1_k127_104969_25 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
PYH1_k127_104969_26 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006243 269.0
PYH1_k127_104969_27 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003936 273.0
PYH1_k127_104969_28 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
PYH1_k127_104969_29 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000001165 259.0
PYH1_k127_104969_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 518.0
PYH1_k127_104969_30 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000000005494 212.0
PYH1_k127_104969_31 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000000000005746 218.0
PYH1_k127_104969_32 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000003005 215.0
PYH1_k127_104969_33 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000004181 224.0
PYH1_k127_104969_34 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000125 192.0
PYH1_k127_104969_35 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000002864 194.0
PYH1_k127_104969_36 heptosyltransferase K02841 - - 0.000000000000000000000000000000000000000000000000006127 194.0
PYH1_k127_104969_37 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000000000000000000006563 194.0
PYH1_k127_104969_38 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000002579 181.0
PYH1_k127_104969_39 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000001891 179.0
PYH1_k127_104969_4 surface antigen (D15) K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 484.0
PYH1_k127_104969_40 Psort location Cytoplasmic, score 8.96 K09949 - - 0.0000000000000000000000000000000000000004801 159.0
PYH1_k127_104969_41 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000002075 150.0
PYH1_k127_104969_42 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000002191 154.0
PYH1_k127_104969_43 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000006546 143.0
PYH1_k127_104969_44 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000001132 139.0
PYH1_k127_104969_45 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000008812 119.0
PYH1_k127_104969_46 Phospholipid methyltransferase - - - 0.00000000000000000000000001085 117.0
PYH1_k127_104969_47 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000001507 115.0
PYH1_k127_104969_48 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000004822 108.0
PYH1_k127_104969_49 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000002026 103.0
PYH1_k127_104969_5 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 449.0
PYH1_k127_104969_51 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000004198 89.0
PYH1_k127_104969_52 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001933 83.0
PYH1_k127_104969_53 Protein of unknown function (DUF2905) - - - 0.0000000000000001575 83.0
PYH1_k127_104969_54 Belongs to the UPF0434 family K09791 - - 0.00000000000001123 78.0
PYH1_k127_104969_55 Outer membrane protein (OmpH-like) K06142 - - 0.00000000009055 70.0
PYH1_k127_104969_56 Helix-hairpin-helix motif K02237 - - 0.00001152 56.0
PYH1_k127_104969_57 - - - - 0.0001081 53.0
PYH1_k127_104969_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 434.0
PYH1_k127_104969_7 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 411.0
PYH1_k127_104969_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 400.0
PYH1_k127_104969_9 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 384.0
PYH1_k127_1060847_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 499.0
PYH1_k127_1060847_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000005848 148.0
PYH1_k127_1065605_0 AcrB/AcrD/AcrF family K03296 - - 1.246e-269 846.0
PYH1_k127_1065605_1 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 368.0
PYH1_k127_1078932_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 7.23e-210 680.0
PYH1_k127_1078932_1 IMP dehydrogenase / GMP reductase domain K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 516.0
PYH1_k127_1078932_10 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000001363 168.0
PYH1_k127_1078932_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000001325 165.0
PYH1_k127_1078932_12 Sporulation and spore germination - - - 0.0000000000000000000001169 108.0
PYH1_k127_1078932_13 RDD family - - - 0.00000000000000001373 91.0
PYH1_k127_1078932_14 Transmembrane and - - - 0.00000000000001056 86.0
PYH1_k127_1078932_15 - - - - 0.000001036 51.0
PYH1_k127_1078932_16 Belongs to the pirin family K06911 - - 0.00000182 56.0
PYH1_k127_1078932_2 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 347.0
PYH1_k127_1078932_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
PYH1_k127_1078932_4 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000284 285.0
PYH1_k127_1078932_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001838 268.0
PYH1_k127_1078932_6 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000002659 229.0
PYH1_k127_1078932_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000002146 203.0
PYH1_k127_1078932_8 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000002153 189.0
PYH1_k127_1078932_9 Protein of unknown function (DUF3187) - - - 0.0000000000000000000000000000000000000000005111 171.0
PYH1_k127_1113465_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 556.0
PYH1_k127_1113465_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 460.0
PYH1_k127_1113465_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000005347 144.0
PYH1_k127_1113465_11 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000004503 111.0
PYH1_k127_1113465_12 energy transducer activity K03646,K03832 - - 0.000000000000000000000004354 112.0
PYH1_k127_1113465_14 all-trans-retinol 13,14-reductase activity - - - 0.000004446 59.0
PYH1_k127_1113465_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 377.0
PYH1_k127_1113465_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 334.0
PYH1_k127_1113465_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 336.0
PYH1_k127_1113465_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 295.0
PYH1_k127_1113465_6 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 260.0
PYH1_k127_1113465_7 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
PYH1_k127_1113465_8 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000005254 217.0
PYH1_k127_1113465_9 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000005412 156.0
PYH1_k127_1140753_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 430.0
PYH1_k127_1140753_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 357.0
PYH1_k127_1140753_10 - - - - 0.000001615 60.0
PYH1_k127_1140753_2 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000278 216.0
PYH1_k127_1140753_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000002188 199.0
PYH1_k127_1140753_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000004306 188.0
PYH1_k127_1140753_5 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000006484 111.0
PYH1_k127_1140753_6 Tetratricopeptide repeat - - - 0.0000000000000003345 88.0
PYH1_k127_1140753_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000002778 72.0
PYH1_k127_1140753_8 Peptidase family M28 - - - 0.0000001906 63.0
PYH1_k127_1140753_9 - - - - 0.0000002055 58.0
PYH1_k127_1147411_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
PYH1_k127_1147411_1 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001042 287.0
PYH1_k127_1147411_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
PYH1_k127_1147411_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001607 271.0
PYH1_k127_1147411_4 Scavenger mRNA decapping enzyme C-term binding - - - 0.000000000000000000000000000000000000000000000006229 175.0
PYH1_k127_1147411_5 sequence-specific DNA binding - - - 0.000000000000000000000000000000002376 134.0
PYH1_k127_1147411_6 YCII-related domain - - - 0.00000000000000000000000000007684 117.0
PYH1_k127_1147411_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000004913 61.0
PYH1_k127_1173120_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665,K02619,K03342,K13503,K13950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 439.0
PYH1_k127_1173120_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000005259 240.0
PYH1_k127_1173120_2 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000006418 170.0
PYH1_k127_1173120_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000001621 147.0
PYH1_k127_1173120_4 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000001123 120.0
PYH1_k127_1173120_5 TfoX N-terminal domain - - - 0.00000000000000004282 89.0
PYH1_k127_1173120_6 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000002272 77.0
PYH1_k127_1242596_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 1.259e-249 786.0
PYH1_k127_1242596_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.396e-236 739.0
PYH1_k127_1242596_2 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 595.0
PYH1_k127_1242596_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 458.0
PYH1_k127_1242596_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000028 243.0
PYH1_k127_1242596_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000004505 216.0
PYH1_k127_1242596_6 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000344 186.0
PYH1_k127_1242596_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000001449 181.0
PYH1_k127_1242596_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000001874 144.0
PYH1_k127_1242596_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000006695 138.0
PYH1_k127_1297197_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1230.0
PYH1_k127_1297197_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.215e-205 652.0
PYH1_k127_1297197_10 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000001868 218.0
PYH1_k127_1297197_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000001152 213.0
PYH1_k127_1297197_12 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000001865 128.0
PYH1_k127_1297197_13 - - - - 0.0000000001151 65.0
PYH1_k127_1297197_14 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000001635 57.0
PYH1_k127_1297197_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 591.0
PYH1_k127_1297197_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 434.0
PYH1_k127_1297197_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 407.0
PYH1_k127_1297197_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 395.0
PYH1_k127_1297197_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 355.0
PYH1_k127_1297197_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003273 265.0
PYH1_k127_1297197_8 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000001097 258.0
PYH1_k127_1297197_9 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000005646 224.0
PYH1_k127_13139_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000003443 214.0
PYH1_k127_13139_1 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000003318 151.0
PYH1_k127_13139_2 Chemotaxis protein CheA K03407 - 2.7.13.3 0.00000000000000000000000000000000003164 145.0
PYH1_k127_13139_3 Two component signalling adaptor domain K03408 - - 0.00000000009339 69.0
PYH1_k127_132920_0 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000001185 91.0
PYH1_k127_132920_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000005487 90.0
PYH1_k127_132920_2 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000001223 71.0
PYH1_k127_132920_3 Diguanylate cyclase K21023 - 2.7.7.65 0.000000009679 57.0
PYH1_k127_1334438_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
PYH1_k127_1334438_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000004235 201.0
PYH1_k127_1334438_2 lysyltransferase activity - - - 0.000000000000000000000000001077 125.0
PYH1_k127_1334438_3 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000001403 87.0
PYH1_k127_1399214_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 308.0
PYH1_k127_1399214_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000005098 145.0
PYH1_k127_1399214_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000002637 54.0
PYH1_k127_1450002_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000001291 214.0
PYH1_k127_1450002_1 DNA polymerase beta domain protein region K07075 - - 0.0000000000000008811 79.0
PYH1_k127_1476462_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
PYH1_k127_1476462_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000004084 160.0
PYH1_k127_1476462_2 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000003444 116.0
PYH1_k127_1476462_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000582 91.0
PYH1_k127_1611681_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 511.0
PYH1_k127_1611681_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 305.0
PYH1_k127_1611681_2 Periplasmic binding protein K07121 - - 0.0000000000000000000000000000000000000000000000000000003196 216.0
PYH1_k127_1611681_3 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000001466 188.0
PYH1_k127_1611681_4 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000003461 175.0
PYH1_k127_1661372_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 364.0
PYH1_k127_1661372_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 259.0
PYH1_k127_1661372_2 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003686 269.0
PYH1_k127_1661372_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007413 255.0
PYH1_k127_1661372_4 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000001497 228.0
PYH1_k127_1661372_5 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.0000000000000000000000000000003918 130.0
PYH1_k127_1661372_6 Protein involved in outer membrane biogenesis K07289 - - 0.00000000000001602 86.0
PYH1_k127_1661372_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000003341 87.0
PYH1_k127_1661372_8 - - - - 0.000000000000146 83.0
PYH1_k127_170748_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.299e-226 720.0
PYH1_k127_170748_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001957 217.0
PYH1_k127_170748_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001438 207.0
PYH1_k127_170748_3 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000006011 199.0
PYH1_k127_170748_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000001693 190.0
PYH1_k127_170748_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000003752 169.0
PYH1_k127_170748_6 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000002599 160.0
PYH1_k127_170748_7 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000003254 148.0
PYH1_k127_170748_8 Belongs to the carbohydrate kinase PfkB family K21056 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.212 0.000000000000000000000000003082 118.0
PYH1_k127_170748_9 - - - - 0.0003146 50.0
PYH1_k127_1751112_0 UvrD/REP helicase N-terminal domain - - - 2.028e-232 757.0
PYH1_k127_1751112_1 exonuclease activity K16899 - 3.6.4.12 3.776e-205 675.0
PYH1_k127_1751112_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 542.0
PYH1_k127_1751112_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 356.0
PYH1_k127_1751112_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000376 244.0
PYH1_k127_1751112_5 - - - - 0.0000000000000000000000000000000000000000000000000003089 204.0
PYH1_k127_1751112_6 - - - - 0.000000000000000000000000000000000000000000000007977 176.0
PYH1_k127_1751112_7 - - - - 0.000000000000000000000000000000007954 140.0
PYH1_k127_175622_0 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000000000000003343 179.0
PYH1_k127_1766531_1 cellulase activity K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000001492 179.0
PYH1_k127_1766531_2 Sigma-54 interaction domain - - - 0.0000000001279 63.0
PYH1_k127_1844350_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.149e-273 853.0
PYH1_k127_1844350_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.031e-244 782.0
PYH1_k127_1844350_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 291.0
PYH1_k127_1844350_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000001154 278.0
PYH1_k127_1844350_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
PYH1_k127_1844350_13 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002286 261.0
PYH1_k127_1844350_14 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000008707 229.0
PYH1_k127_1844350_15 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000002337 205.0
PYH1_k127_1844350_16 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000321 197.0
PYH1_k127_1844350_17 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000001831 184.0
PYH1_k127_1844350_18 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000006978 165.0
PYH1_k127_1844350_19 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000459 170.0
PYH1_k127_1844350_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 595.0
PYH1_k127_1844350_20 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000004686 167.0
PYH1_k127_1844350_21 AI-2E family transporter - - - 0.000000000000000000000000000000000000002589 160.0
PYH1_k127_1844350_22 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000004438 137.0
PYH1_k127_1844350_23 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000005222 137.0
PYH1_k127_1844350_24 nucleotidyltransferase activity K01154,K07076,K18842 - 3.1.21.3 0.00000000000000000000000000000005046 128.0
PYH1_k127_1844350_25 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000007401 133.0
PYH1_k127_1844350_26 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000002312 119.0
PYH1_k127_1844350_27 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000005583 115.0
PYH1_k127_1844350_28 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000001064 114.0
PYH1_k127_1844350_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 558.0
PYH1_k127_1844350_30 PFAM S23 ribosomal protein - - - 0.00000000000000000001424 104.0
PYH1_k127_1844350_31 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000003428 91.0
PYH1_k127_1844350_32 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000004481 75.0
PYH1_k127_1844350_33 Helix-turn-helix domain - - - 0.0000000000001579 79.0
PYH1_k127_1844350_34 - - - - 0.00000000007293 70.0
PYH1_k127_1844350_35 HEPN domain K09132 - - 0.000000000451 67.0
PYH1_k127_1844350_36 Chain length determinant protein K16692 - - 0.00000007907 61.0
PYH1_k127_1844350_4 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 515.0
PYH1_k127_1844350_5 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 476.0
PYH1_k127_1844350_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 432.0
PYH1_k127_1844350_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 376.0
PYH1_k127_1844350_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 357.0
PYH1_k127_1844350_9 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 332.0
PYH1_k127_1872087_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 576.0
PYH1_k127_1872087_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 509.0
PYH1_k127_1872087_10 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000007445 66.0
PYH1_k127_1872087_2 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004892 274.0
PYH1_k127_1872087_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
PYH1_k127_1872087_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000002127 209.0
PYH1_k127_1872087_5 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000002903 170.0
PYH1_k127_1872087_6 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000002089 167.0
PYH1_k127_1872087_7 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000003235 150.0
PYH1_k127_1872087_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000437 127.0
PYH1_k127_1872087_9 phosphorelay signal transduction system - - - 0.0000000000000000000000003482 112.0
PYH1_k127_1936041_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 545.0
PYH1_k127_1936041_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 325.0
PYH1_k127_1936041_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
PYH1_k127_1964353_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 310.0
PYH1_k127_1964353_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 255.0
PYH1_k127_1964353_2 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005311 250.0
PYH1_k127_1964353_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000001212 237.0
PYH1_k127_1964353_4 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000001591 194.0
PYH1_k127_1964353_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000004286 63.0
PYH1_k127_2002564_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 529.0
PYH1_k127_2002564_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000005931 228.0
PYH1_k127_2002564_2 PFAM glutaredoxin - - - 0.0000000000000000000000002071 108.0
PYH1_k127_2002564_3 PIN domain K07064 - - 0.000000000000001626 83.0
PYH1_k127_2027663_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1189.0
PYH1_k127_2027663_1 impB/mucB/samB family K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 379.0
PYH1_k127_2106938_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 588.0
PYH1_k127_2106938_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 541.0
PYH1_k127_2106938_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 294.0
PYH1_k127_2106938_11 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
PYH1_k127_2106938_12 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000235 263.0
PYH1_k127_2106938_13 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
PYH1_k127_2106938_14 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000001497 152.0
PYH1_k127_2106938_15 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000001802 126.0
PYH1_k127_2106938_16 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000563 132.0
PYH1_k127_2106938_17 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000454 125.0
PYH1_k127_2106938_18 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000001216 85.0
PYH1_k127_2106938_19 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000002314 57.0
PYH1_k127_2106938_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 517.0
PYH1_k127_2106938_3 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 488.0
PYH1_k127_2106938_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
PYH1_k127_2106938_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 387.0
PYH1_k127_2106938_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 366.0
PYH1_k127_2106938_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 363.0
PYH1_k127_2106938_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 312.0
PYH1_k127_2106938_9 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 325.0
PYH1_k127_2108058_0 CBS domain containing protein K00974 - 2.7.7.72 1.014e-219 707.0
PYH1_k127_2108058_1 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000002257 150.0
PYH1_k127_2108058_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000001891 61.0
PYH1_k127_2138117_0 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 411.0
PYH1_k127_2138117_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 385.0
PYH1_k127_2138117_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000003048 217.0
PYH1_k127_2138117_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000448 194.0
PYH1_k127_2138117_4 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000006437 78.0
PYH1_k127_2138117_5 Protein of unknown function (DUF3343) - - - 0.0002242 50.0
PYH1_k127_2165474_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 372.0
PYH1_k127_2165474_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000001811 154.0
PYH1_k127_2165474_11 Photosynthesis system II assembly factor YCF48 - - - 0.00007729 56.0
PYH1_k127_2165474_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000007639 157.0
PYH1_k127_2165474_3 Thioredoxin-like - - - 0.000000000000000000000000000000000181 140.0
PYH1_k127_2165474_5 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000000000000000001994 130.0
PYH1_k127_2165474_6 NHL repeat - - - 0.0000000000000000000000625 115.0
PYH1_k127_2165474_7 PFAM UvrB UvrC protein - - - 0.000000000001839 75.0
PYH1_k127_2165474_8 GDSL-like Lipase/Acylhydrolase - - - 0.00000000003417 78.0
PYH1_k127_2165474_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000003698 76.0
PYH1_k127_2186985_0 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000004555 185.0
PYH1_k127_2186985_1 Domain of unknown function (DUF4349) - - - 0.0000000000000000000007606 107.0
PYH1_k127_2186985_2 Tetratricopeptide repeat - - - 0.0006269 47.0
PYH1_k127_2251011_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000135 199.0
PYH1_k127_2251011_1 Cytochrome P460 - - - 0.000000000000000000000000000001244 130.0
PYH1_k127_2251011_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000002094 127.0
PYH1_k127_2251011_3 Zn-dependent protease - - - 0.00001961 53.0
PYH1_k127_2251011_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001993 51.0
PYH1_k127_2295654_0 ASPIC and UnbV - - - 4.756e-196 624.0
PYH1_k127_2295654_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 497.0
PYH1_k127_2295654_10 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000000000000000000000000000000000000001126 197.0
PYH1_k127_2295654_11 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000006819 207.0
PYH1_k127_2295654_12 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000009693 163.0
PYH1_k127_2295654_13 - - - - 0.00000000000000000000000000000000000004316 164.0
PYH1_k127_2295654_15 - - - - 0.000000000000000000000002739 114.0
PYH1_k127_2295654_16 amine dehydrogenase activity - - - 0.0000000000000004845 91.0
PYH1_k127_2295654_17 nitric oxide dioxygenase activity - - - 0.000000000000007257 78.0
PYH1_k127_2295654_19 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000004026 70.0
PYH1_k127_2295654_2 denitrification pathway K02569,K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 492.0
PYH1_k127_2295654_20 - - - - 0.00000000005622 67.0
PYH1_k127_2295654_21 Periplasmic copper-binding protein (NosD) - - - 0.00001197 57.0
PYH1_k127_2295654_22 peptidase U32 - - - 0.00004106 56.0
PYH1_k127_2295654_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 409.0
PYH1_k127_2295654_4 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 379.0
PYH1_k127_2295654_5 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
PYH1_k127_2295654_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
PYH1_k127_2295654_7 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001254 255.0
PYH1_k127_2295654_8 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000003033 237.0
PYH1_k127_2372010_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 7.521e-283 886.0
PYH1_k127_2372010_1 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 2.612e-202 640.0
PYH1_k127_2372010_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
PYH1_k127_2372010_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000009153 213.0
PYH1_k127_2372010_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000002159 146.0
PYH1_k127_2372010_5 - - - - 0.000000000000000000001975 100.0
PYH1_k127_2372010_6 4Fe-4S binding domain - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.00000000000000000008567 96.0
PYH1_k127_2372010_7 - - - - 0.0000000000000147 80.0
PYH1_k127_2372010_8 Short C-terminal domain K08982 - - 0.000000000005994 69.0
PYH1_k127_2372010_9 Protein of unknown function (DUF1761) - - - 0.0000000009595 64.0
PYH1_k127_2441103_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000307 184.0
PYH1_k127_2441103_1 ABC transporter substrate binding protein - - - 0.000000002279 68.0
PYH1_k127_2476897_0 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 550.0
PYH1_k127_2476897_1 Domain of unknown function (DUF1925) K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 516.0
PYH1_k127_2476897_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 389.0
PYH1_k127_2476897_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 306.0
PYH1_k127_2477680_0 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000169 217.0
PYH1_k127_2477680_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000004183 179.0
PYH1_k127_2477680_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.0000000000000000000000000000005892 128.0
PYH1_k127_2477680_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000004501 117.0
PYH1_k127_2477680_4 Transmembrane and - - - 0.000000000000004155 87.0
PYH1_k127_2496659_0 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 473.0
PYH1_k127_2496659_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 478.0
PYH1_k127_2519392_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 604.0
PYH1_k127_2519392_1 RnfC Barrel sandwich hybrid domain K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 464.0
PYH1_k127_2519392_10 Part of a membrane complex involved in electron transport K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000002564 111.0
PYH1_k127_2519392_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001097 294.0
PYH1_k127_2519392_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001733 235.0
PYH1_k127_2519392_4 ATP cone domain K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000005207 224.0
PYH1_k127_2519392_5 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000006101 216.0
PYH1_k127_2519392_6 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000000003632 211.0
PYH1_k127_2519392_7 Rnf-Nqr subunit, membrane protein K03617 - - 0.000000000000000000000000000000000000000000000000000003115 199.0
PYH1_k127_2519392_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000001709 189.0
PYH1_k127_2519392_9 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000003564 180.0
PYH1_k127_2551410_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
PYH1_k127_2551410_1 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003182 274.0
PYH1_k127_2551410_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002831 262.0
PYH1_k127_2551410_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008658 243.0
PYH1_k127_2551410_4 ABC-type transport system involved in lipoprotein release permease component - - - 0.000000000000000000000000000000000000000000000000000000002669 216.0
PYH1_k127_2551410_5 - - - - 0.000000000000000000000000000000000002938 141.0
PYH1_k127_2551410_6 - - - - 0.0000000000009004 81.0
PYH1_k127_2583675_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 426.0
PYH1_k127_2583675_1 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000002175 242.0
PYH1_k127_2583675_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000005536 214.0
PYH1_k127_2583675_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000004662 166.0
PYH1_k127_2593885_0 P2 response regulator binding domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 340.0
PYH1_k127_2593885_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 310.0
PYH1_k127_2593885_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000001064 145.0
PYH1_k127_2593885_3 CheC-like family K03410 - - 0.000000000000000000000000000001539 130.0
PYH1_k127_2627521_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 527.0
PYH1_k127_2627521_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 370.0
PYH1_k127_2627521_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 347.0
PYH1_k127_2627521_3 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 333.0
PYH1_k127_2627521_4 domain, Protein - - - 0.0000000002976 68.0
PYH1_k127_2627521_5 Uncharacterized protein family, UPF0114 - - - 0.0008049 50.0
PYH1_k127_2640516_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.355e-279 871.0
PYH1_k127_2640516_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.844e-210 685.0
PYH1_k127_2640516_10 PFAM CBS domain - - - 0.00000000000000000000000000000000001977 148.0
PYH1_k127_2640516_11 PFAM YbbR family protein - - - 0.000000000000000000000000000000002463 137.0
PYH1_k127_2640516_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000005474 118.0
PYH1_k127_2640516_13 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000003651 123.0
PYH1_k127_2640516_14 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00002338 53.0
PYH1_k127_2640516_2 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 565.0
PYH1_k127_2640516_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 464.0
PYH1_k127_2640516_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 429.0
PYH1_k127_2640516_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 396.0
PYH1_k127_2640516_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 327.0
PYH1_k127_2640516_7 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 302.0
PYH1_k127_2640516_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000004514 250.0
PYH1_k127_2640516_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000006768 213.0
PYH1_k127_2655462_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.376e-263 820.0
PYH1_k127_2655462_1 Domain of unknown function (DUF3552) K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 616.0
PYH1_k127_2655462_10 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004479 256.0
PYH1_k127_2655462_11 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000005738 202.0
PYH1_k127_2655462_12 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000001373 222.0
PYH1_k127_2655462_13 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000005095 172.0
PYH1_k127_2655462_14 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000001638 171.0
PYH1_k127_2655462_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000004551 150.0
PYH1_k127_2655462_16 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000339 151.0
PYH1_k127_2655462_17 5-Formyltetrahydrofolate Cyclo-Ligase K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000007843 114.0
PYH1_k127_2655462_18 Roadblock/LC7 domain - - - 0.0000000000000000000002072 101.0
PYH1_k127_2655462_19 Tetratricopeptide repeat - - - 0.0000000000000000002233 104.0
PYH1_k127_2655462_2 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 587.0
PYH1_k127_2655462_20 biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000002234 101.0
PYH1_k127_2655462_21 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000003016 79.0
PYH1_k127_2655462_22 PAP2 superfamily - - - 0.000001104 61.0
PYH1_k127_2655462_23 Sporulation related domain - - - 0.00006807 55.0
PYH1_k127_2655462_3 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 588.0
PYH1_k127_2655462_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
PYH1_k127_2655462_5 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 325.0
PYH1_k127_2655462_6 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
PYH1_k127_2655462_7 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
PYH1_k127_2655462_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003553 263.0
PYH1_k127_2655462_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
PYH1_k127_2803669_0 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 415.0
PYH1_k127_2803669_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 349.0
PYH1_k127_2803669_2 COG1032 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
PYH1_k127_2803669_3 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
PYH1_k127_2803669_4 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006017 249.0
PYH1_k127_2803669_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000009626 201.0
PYH1_k127_2803669_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000142 82.0
PYH1_k127_2877440_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 400.0
PYH1_k127_2877440_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 386.0
PYH1_k127_2877440_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001663 234.0
PYH1_k127_2877440_3 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000002166 220.0
PYH1_k127_2877440_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000002463 131.0
PYH1_k127_2877440_5 - - - - 0.00000000000000000000006186 115.0
PYH1_k127_2979099_0 potassium uptake protein TrkH K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 510.0
PYH1_k127_2979099_1 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 325.0
PYH1_k127_2979099_2 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
PYH1_k127_2979099_3 PFAM cation transporter K03498 - - 0.000000000000000000000000000000000000000000000000000000001964 206.0
PYH1_k127_2979099_4 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
PYH1_k127_2979099_5 domain protein K03499 - - 0.00000000000000000000000000000000000000000000000002191 186.0
PYH1_k127_2979099_6 - - - - 0.000000000000000000002678 102.0
PYH1_k127_32623_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000004062 176.0
PYH1_k127_32623_1 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.000000000000000000000000000005268 137.0
PYH1_k127_3309931_0 Belongs to the glutamate synthase family - - - 1.164e-245 766.0
PYH1_k127_3309931_1 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 1.366e-239 768.0
PYH1_k127_3309931_10 - - - - 0.0002962 43.0
PYH1_k127_3309931_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 566.0
PYH1_k127_3309931_3 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 500.0
PYH1_k127_3309931_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 368.0
PYH1_k127_3309931_5 PFAM glutamate synthase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 276.0
PYH1_k127_3309931_6 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005224 197.0
PYH1_k127_3309931_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000004982 178.0
PYH1_k127_3309931_8 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000004257 174.0
PYH1_k127_3309931_9 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000215 124.0
PYH1_k127_3325203_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 312.0
PYH1_k127_3325203_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006663 241.0
PYH1_k127_3370731_0 Elongation factor Tu domain 2 K02355 - - 6.92e-223 711.0
PYH1_k127_3370731_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 437.0
PYH1_k127_3370731_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 343.0
PYH1_k127_3370731_3 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000009517 239.0
PYH1_k127_3370731_4 Competence protein K02238 - - 0.000000000000000000000000000002204 139.0
PYH1_k127_3370731_5 - - - - 0.00000000000000000000001177 114.0
PYH1_k127_3370731_6 His Kinase A (phosphoacceptor) domain - - - 0.00006682 54.0
PYH1_k127_3388099_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 471.0
PYH1_k127_3404646_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1243.0
PYH1_k127_3404646_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.241e-207 661.0
PYH1_k127_3404646_10 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 381.0
PYH1_k127_3404646_11 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 361.0
PYH1_k127_3404646_12 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 372.0
PYH1_k127_3404646_13 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 354.0
PYH1_k127_3404646_14 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 321.0
PYH1_k127_3404646_15 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 328.0
PYH1_k127_3404646_16 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 304.0
PYH1_k127_3404646_17 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 291.0
PYH1_k127_3404646_18 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
PYH1_k127_3404646_19 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001751 278.0
PYH1_k127_3404646_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 562.0
PYH1_k127_3404646_20 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001404 264.0
PYH1_k127_3404646_21 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
PYH1_k127_3404646_22 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000004322 231.0
PYH1_k127_3404646_23 Ribonuclease HII K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000751 204.0
PYH1_k127_3404646_24 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000738 194.0
PYH1_k127_3404646_25 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000003219 210.0
PYH1_k127_3404646_26 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.0000000000000000000000000000000000000000001408 184.0
PYH1_k127_3404646_27 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000013 158.0
PYH1_k127_3404646_28 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000001386 158.0
PYH1_k127_3404646_29 large ribosomal subunit rRNA binding K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001797 146.0
PYH1_k127_3404646_3 surface antigen variable number repeat protein K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 533.0
PYH1_k127_3404646_30 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000001602 147.0
PYH1_k127_3404646_31 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000001215 142.0
PYH1_k127_3404646_32 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000005097 119.0
PYH1_k127_3404646_33 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000001354 126.0
PYH1_k127_3404646_34 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000001161 117.0
PYH1_k127_3404646_35 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000005272 110.0
PYH1_k127_3404646_36 PFAM FecR protein - - - 0.000000000000000000000001096 119.0
PYH1_k127_3404646_37 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000001334 108.0
PYH1_k127_3404646_38 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000003311 102.0
PYH1_k127_3404646_39 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000006171 88.0
PYH1_k127_3404646_4 ATPase with chaperone activity K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 478.0
PYH1_k127_3404646_40 protein secretion K03116 - - 0.000000000000000003419 85.0
PYH1_k127_3404646_41 regulatory protein, arsR - - - 0.00000000000000000605 86.0
PYH1_k127_3404646_42 PFAM GGDEF domain containing protein - - - 0.00000000000006155 87.0
PYH1_k127_3404646_43 NhaP-type Na H and K H - - - 0.00000000001275 77.0
PYH1_k127_3404646_44 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000001945 74.0
PYH1_k127_3404646_45 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000001112 70.0
PYH1_k127_3404646_46 Part of a membrane complex involved in electron transport K03617 - - 0.000000007211 60.0
PYH1_k127_3404646_47 - - - - 0.0000405 53.0
PYH1_k127_3404646_48 sequence-specific DNA binding K15539 - - 0.00004662 53.0
PYH1_k127_3404646_49 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000551 49.0
PYH1_k127_3404646_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
PYH1_k127_3404646_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 454.0
PYH1_k127_3404646_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 449.0
PYH1_k127_3404646_8 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 448.0
PYH1_k127_3404646_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH1_k127_3416548_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000001307 225.0
PYH1_k127_3416548_1 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000287 185.0
PYH1_k127_3416548_2 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003328 176.0
PYH1_k127_3416548_3 PFAM Integrase catalytic region - - - 0.000000001858 61.0
PYH1_k127_3418240_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000001124 229.0
PYH1_k127_3418240_1 PFAM Glycosyl transferase, family 2 K00721,K00786 - 2.4.1.83 0.000000000000000000000000000004597 128.0
PYH1_k127_3418240_2 histidine kinase A domain protein - - - 0.0000000003647 70.0
PYH1_k127_3459180_0 PFAM ferredoxin-dependent glutamate synthase - - - 9.159e-286 883.0
PYH1_k127_3459180_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.394e-239 753.0
PYH1_k127_3459180_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000007691 149.0
PYH1_k127_3459180_11 SMART regulatory protein ArsR - - - 0.00000000000000000000000000000832 122.0
PYH1_k127_3459180_12 - - - - 0.0000000000000000000000003638 121.0
PYH1_k127_3459180_13 Thioredoxin domain - - - 0.000000000000000000000004033 103.0
PYH1_k127_3459180_15 Protein kinase domain - - - 0.000000004317 61.0
PYH1_k127_3459180_2 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 559.0
PYH1_k127_3459180_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 365.0
PYH1_k127_3459180_4 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 346.0
PYH1_k127_3459180_5 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 328.0
PYH1_k127_3459180_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
PYH1_k127_3459180_7 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000003055 244.0
PYH1_k127_3459180_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000002728 149.0
PYH1_k127_3459180_9 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000003925 142.0
PYH1_k127_3496265_0 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 5.347e-219 721.0
PYH1_k127_3496265_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 604.0
PYH1_k127_3496265_10 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 358.0
PYH1_k127_3496265_11 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001041 293.0
PYH1_k127_3496265_12 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000002233 271.0
PYH1_k127_3496265_13 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000006481 240.0
PYH1_k127_3496265_14 Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing - - - 0.00000000000000000000000000000000000000000000000000005373 193.0
PYH1_k127_3496265_15 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000003646 202.0
PYH1_k127_3496265_16 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000002344 188.0
PYH1_k127_3496265_17 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000007569 186.0
PYH1_k127_3496265_18 acetyltransferase K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000001596 191.0
PYH1_k127_3496265_19 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000002845 198.0
PYH1_k127_3496265_2 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 612.0
PYH1_k127_3496265_20 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000001314 180.0
PYH1_k127_3496265_21 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000002198 170.0
PYH1_k127_3496265_22 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000002335 171.0
PYH1_k127_3496265_23 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000002516 151.0
PYH1_k127_3496265_24 - K16923 - - 0.000000000000000000000000000002511 141.0
PYH1_k127_3496265_25 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000009832 110.0
PYH1_k127_3496265_26 PFAM FMN-binding domain K21559 - - 0.00000000000000000000319 107.0
PYH1_k127_3496265_28 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000001797 69.0
PYH1_k127_3496265_29 Tetratricopeptide repeat - - - 0.0000004043 62.0
PYH1_k127_3496265_3 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 434.0
PYH1_k127_3496265_4 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 412.0
PYH1_k127_3496265_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 414.0
PYH1_k127_3496265_6 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH1_k127_3496265_7 PRTRC system protein D K18640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH1_k127_3496265_8 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 339.0
PYH1_k127_3496265_9 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 347.0
PYH1_k127_3503613_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.561e-298 938.0
PYH1_k127_3503613_1 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 624.0
PYH1_k127_3503613_10 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000004538 82.0
PYH1_k127_3503613_11 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.00000000000009228 78.0
PYH1_k127_3503613_12 Fimbrial assembly family protein K02461 - - 0.0000000007391 71.0
PYH1_k127_3503613_13 Prokaryotic N-terminal methylation motif K02457 - - 0.0000007159 60.0
PYH1_k127_3503613_14 general secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000003366 57.0
PYH1_k127_3503613_15 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0002177 51.0
PYH1_k127_3503613_16 overlaps another CDS with the same product name K02458 - - 0.0006192 51.0
PYH1_k127_3503613_17 Belongs to the peptidase S8 family K13274,K20276 - - 0.0008714 46.0
PYH1_k127_3503613_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 512.0
PYH1_k127_3503613_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 502.0
PYH1_k127_3503613_4 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
PYH1_k127_3503613_5 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
PYH1_k127_3503613_6 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000247 194.0
PYH1_k127_3503613_7 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000000000000000004353 178.0
PYH1_k127_3503613_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000007541 133.0
PYH1_k127_3503613_9 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000001097 141.0
PYH1_k127_3562426_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K00170 - 1.2.7.1 1.211e-299 940.0
PYH1_k127_3562426_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.096e-263 827.0
PYH1_k127_3562426_10 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
PYH1_k127_3562426_11 ferredoxin K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 348.0
PYH1_k127_3562426_12 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 340.0
PYH1_k127_3562426_13 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 304.0
PYH1_k127_3562426_14 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001332 284.0
PYH1_k127_3562426_15 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
PYH1_k127_3562426_16 Cytochrome b5-like Heme/Steroid binding domain K07245,K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000003127 233.0
PYH1_k127_3562426_17 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000001961 178.0
PYH1_k127_3562426_18 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000003517 159.0
PYH1_k127_3562426_19 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000006795 147.0
PYH1_k127_3562426_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.38e-241 758.0
PYH1_k127_3562426_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000001912 143.0
PYH1_k127_3562426_21 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.00000000000000000000000000000003217 132.0
PYH1_k127_3562426_22 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000006367 114.0
PYH1_k127_3562426_23 QueT transporter - - - 0.0000000000000000000007077 103.0
PYH1_k127_3562426_24 Thioesterase superfamily - - - 0.000000000000000001199 93.0
PYH1_k127_3562426_25 Integrin alpha (beta-propellor repeats). - - - 0.0000000003082 72.0
PYH1_k127_3562426_26 HNH endonuclease K07454 - - 0.00000003556 57.0
PYH1_k127_3562426_27 - - - - 0.0001288 50.0
PYH1_k127_3562426_3 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 537.0
PYH1_k127_3562426_4 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 448.0
PYH1_k127_3562426_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 447.0
PYH1_k127_3562426_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 424.0
PYH1_k127_3562426_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 401.0
PYH1_k127_3562426_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 383.0
PYH1_k127_3562426_9 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 372.0
PYH1_k127_3591157_0 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 619.0
PYH1_k127_3615719_0 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 477.0
PYH1_k127_3615719_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000009863 126.0
PYH1_k127_3615719_2 Cytochrome C biogenesis protein - - - 0.0000000000000000000000004469 108.0
PYH1_k127_3615719_3 His Kinase A (phosphoacceptor) domain - - - 0.00000007259 53.0
PYH1_k127_3634855_0 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 327.0
PYH1_k127_3634855_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000005346 152.0
PYH1_k127_3634855_2 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000002424 91.0
PYH1_k127_3634855_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00003771 48.0
PYH1_k127_3720554_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 5.143e-263 831.0
PYH1_k127_3720554_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 1.482e-218 700.0
PYH1_k127_3720554_2 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 486.0
PYH1_k127_3720554_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 311.0
PYH1_k127_3720554_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000005428 229.0
PYH1_k127_3720554_5 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000362 168.0
PYH1_k127_3775269_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
PYH1_k127_3775269_1 PFAM GGDEF domain containing protein, response regulator receiver - - - 0.00000000000000000000000000000000001934 147.0
PYH1_k127_3775269_2 Glutaredoxin K03676 - - 0.000000002038 59.0
PYH1_k127_3806847_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000001574 220.0
PYH1_k127_3806847_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001155 209.0
PYH1_k127_3806847_2 cell redox homeostasis K03671 - - 0.00000000000009718 77.0
PYH1_k127_3806847_3 SurA N-terminal domain K01802,K03770 - 5.2.1.8 0.00006288 56.0
PYH1_k127_386950_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1501.0
PYH1_k127_386950_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 443.0
PYH1_k127_386950_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000003144 194.0
PYH1_k127_386950_11 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000009937 177.0
PYH1_k127_386950_12 cheY-homologous receiver domain - - - 0.0000000000000000000000003768 109.0
PYH1_k127_386950_13 Transglutaminase/protease-like homologues - - - 0.0000000000000000000008584 110.0
PYH1_k127_386950_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 443.0
PYH1_k127_386950_3 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 449.0
PYH1_k127_386950_4 Cytochrome c552 K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 407.0
PYH1_k127_386950_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 392.0
PYH1_k127_386950_6 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 358.0
PYH1_k127_386950_7 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007654 293.0
PYH1_k127_386950_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000001259 212.0
PYH1_k127_386950_9 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000006276 197.0
PYH1_k127_3905387_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000001593 201.0
PYH1_k127_3905387_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000003109 166.0
PYH1_k127_3905387_2 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000336 158.0
PYH1_k127_4047270_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000008752 151.0
PYH1_k127_4047270_1 - - - - 0.00000000000000000000000000000000000707 141.0
PYH1_k127_4047270_2 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000006803 115.0
PYH1_k127_4047270_3 Permease, YjgP YjgQ - - - 0.00000000001237 76.0
PYH1_k127_4047270_4 PA14 domain - - - 0.00000001523 64.0
PYH1_k127_4047270_5 PFAM CheW domain protein K03408 - - 0.00003175 51.0
PYH1_k127_407740_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.071e-228 712.0
PYH1_k127_407740_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 527.0
PYH1_k127_407740_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 445.0
PYH1_k127_407740_3 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007272 289.0
PYH1_k127_407740_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000961 280.0
PYH1_k127_407740_5 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000002048 252.0
PYH1_k127_407740_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002763 254.0
PYH1_k127_407740_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000002911 228.0
PYH1_k127_407740_8 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000001137 222.0
PYH1_k127_407740_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000005303 144.0
PYH1_k127_4207907_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1058.0
PYH1_k127_4207907_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 2.729e-206 662.0
PYH1_k127_4207907_10 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000004664 179.0
PYH1_k127_4207907_11 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000006336 143.0
PYH1_k127_4207907_12 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000001072 142.0
PYH1_k127_4207907_13 PAP2 superfamily - - - 0.000000000000000000000000000000004021 140.0
PYH1_k127_4207907_14 PFAM AzlC family protein - - - 0.00000000000000000000000000004337 130.0
PYH1_k127_4207907_15 CAAX protease self-immunity - - - 0.000000000000000001249 99.0
PYH1_k127_4207907_16 Domain of unknown function DUF302 - - - 0.00000000002627 67.0
PYH1_k127_4207907_17 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000004826 70.0
PYH1_k127_4207907_2 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0019808,GO:0019809,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 415.0
PYH1_k127_4207907_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
PYH1_k127_4207907_4 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
PYH1_k127_4207907_5 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 321.0
PYH1_k127_4207907_6 GHKL domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003133 292.0
PYH1_k127_4207907_7 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000006193 237.0
PYH1_k127_4207907_8 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000003665 184.0
PYH1_k127_4207907_9 3-beta hydroxysteroid dehydrogenase isomerase K21793 - - 0.00000000000000000000000000000000000000000000001488 193.0
PYH1_k127_4220461_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.362e-300 942.0
PYH1_k127_4220461_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 6.589e-249 781.0
PYH1_k127_4220461_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 348.0
PYH1_k127_4220461_11 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
PYH1_k127_4220461_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
PYH1_k127_4220461_13 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 298.0
PYH1_k127_4220461_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004036 271.0
PYH1_k127_4220461_15 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000001192 239.0
PYH1_k127_4220461_16 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000006939 200.0
PYH1_k127_4220461_17 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000003725 160.0
PYH1_k127_4220461_18 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000002179 143.0
PYH1_k127_4220461_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000007607 135.0
PYH1_k127_4220461_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.353e-234 733.0
PYH1_k127_4220461_20 PFAM BioY K03523 - - 0.00000000000000000000000000000006543 131.0
PYH1_k127_4220461_21 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000001377 130.0
PYH1_k127_4220461_22 PIN domain K07063 - - 0.0000000000000000000000000000003059 127.0
PYH1_k127_4220461_23 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000004488 117.0
PYH1_k127_4220461_24 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000003886 123.0
PYH1_k127_4220461_25 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000000000004492 116.0
PYH1_k127_4220461_26 Binds the 23S rRNA K02909 - - 0.0000000000000000000000005365 105.0
PYH1_k127_4220461_27 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003326 109.0
PYH1_k127_4220461_28 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000113 109.0
PYH1_k127_4220461_29 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000002672 107.0
PYH1_k127_4220461_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.746e-231 723.0
PYH1_k127_4220461_30 diguanylate cyclase - - - 0.0000000000000000003481 100.0
PYH1_k127_4220461_31 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000001097 85.0
PYH1_k127_4220461_32 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005781 74.0
PYH1_k127_4220461_33 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000419 68.0
PYH1_k127_4220461_34 - K21495 - - 0.00000001956 58.0
PYH1_k127_4220461_35 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000002829 63.0
PYH1_k127_4220461_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.121e-217 704.0
PYH1_k127_4220461_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.759e-215 687.0
PYH1_k127_4220461_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.011e-198 629.0
PYH1_k127_4220461_7 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 596.0
PYH1_k127_4220461_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 468.0
PYH1_k127_4220461_9 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 387.0
PYH1_k127_4263964_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 578.0
PYH1_k127_4263964_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
PYH1_k127_4263964_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 4.1.1.11 0.00000000000000000000000000000000006673 136.0
PYH1_k127_4263964_3 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000035 95.0
PYH1_k127_4266604_0 Protein of unknown function, DUF255 K06888 - - 5.25e-198 634.0
PYH1_k127_4266604_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 578.0
PYH1_k127_4266604_10 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000001092 197.0
PYH1_k127_4266604_11 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000002799 188.0
PYH1_k127_4266604_12 HD domain K07814 - - 0.00000000000000000000000000000000000002242 166.0
PYH1_k127_4266604_13 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000001348 153.0
PYH1_k127_4266604_14 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.0000000000000000000000000000000007966 148.0
PYH1_k127_4266604_15 Putative TM nitroreductase - - - 0.000000000000000000000000000000006961 134.0
PYH1_k127_4266604_16 - - - - 0.0000000000000000000000000000001634 127.0
PYH1_k127_4266604_17 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000002018 121.0
PYH1_k127_4266604_18 denitrification pathway - - - 0.000000000000007028 89.0
PYH1_k127_4266604_2 Penicillin-binding protein 1A K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 548.0
PYH1_k127_4266604_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 381.0
PYH1_k127_4266604_4 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 383.0
PYH1_k127_4266604_5 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 324.0
PYH1_k127_4266604_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 319.0
PYH1_k127_4266604_7 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001426 274.0
PYH1_k127_4266604_8 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000004127 276.0
PYH1_k127_4266604_9 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003095 250.0
PYH1_k127_4278671_0 NIL - - - 0.00000000000000000000000000000000000299 142.0
PYH1_k127_4278671_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363 - 0.000000000000000000000000000000001185 140.0
PYH1_k127_4310122_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.168e-240 777.0
PYH1_k127_4310122_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 447.0
PYH1_k127_4310122_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
PYH1_k127_4310122_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 319.0
PYH1_k127_4310122_4 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 303.0
PYH1_k127_4310122_5 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000002666 247.0
PYH1_k127_4310122_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000003859 145.0
PYH1_k127_4310260_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 604.0
PYH1_k127_4310260_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000000000000000000001448 201.0
PYH1_k127_4310260_2 Histidine kinase - - - 0.000000000000000000000000008058 127.0
PYH1_k127_4310260_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000008436 78.0
PYH1_k127_4310260_4 - - - - 0.00000000004744 70.0
PYH1_k127_4310260_5 lyase activity - - - 0.000000002605 70.0
PYH1_k127_4334911_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 578.0
PYH1_k127_4334911_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 295.0
PYH1_k127_4334911_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000005417 271.0
PYH1_k127_4334911_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002976 271.0
PYH1_k127_4334911_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000008551 188.0
PYH1_k127_4380568_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.037e-240 761.0
PYH1_k127_4380568_1 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 2.18e-200 648.0
PYH1_k127_4380568_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000003231 163.0
PYH1_k127_4380568_3 Thioredoxin - - - 0.000001271 57.0
PYH1_k127_4380568_4 by MetaGeneAnnotator - - - 0.000006057 49.0
PYH1_k127_4446177_0 SMART Elongator protein 3 MiaB NifB - - - 2.263e-201 662.0
PYH1_k127_4446177_1 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 576.0
PYH1_k127_4446177_10 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
PYH1_k127_4446177_11 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000001387 221.0
PYH1_k127_4446177_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000002297 207.0
PYH1_k127_4446177_13 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000001453 190.0
PYH1_k127_4446177_14 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001047 176.0
PYH1_k127_4446177_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000873 173.0
PYH1_k127_4446177_16 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000002064 169.0
PYH1_k127_4446177_17 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000004881 162.0
PYH1_k127_4446177_18 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000002423 149.0
PYH1_k127_4446177_19 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001803 133.0
PYH1_k127_4446177_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 574.0
PYH1_k127_4446177_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000002394 130.0
PYH1_k127_4446177_21 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000003848 117.0
PYH1_k127_4446177_22 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001572 109.0
PYH1_k127_4446177_23 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000005288 111.0
PYH1_k127_4446177_24 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000001251 91.0
PYH1_k127_4446177_25 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000004197 84.0
PYH1_k127_4446177_26 FmdB family - - - 0.00000000000001109 77.0
PYH1_k127_4446177_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 573.0
PYH1_k127_4446177_4 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 497.0
PYH1_k127_4446177_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 382.0
PYH1_k127_4446177_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 382.0
PYH1_k127_4446177_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 376.0
PYH1_k127_4446177_8 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
PYH1_k127_4446177_9 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005356 274.0
PYH1_k127_4557395_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 520.0
PYH1_k127_4557395_1 PAS domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 498.0
PYH1_k127_4557395_2 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002522 294.0
PYH1_k127_4557395_3 PFAM metal-dependent phosphohydrolase, HD sub domain K02030 - - 0.00000000001937 77.0
PYH1_k127_4557395_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000001252 71.0
PYH1_k127_4602169_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.063e-211 688.0
PYH1_k127_4602169_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 612.0
PYH1_k127_4602169_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000001062 251.0
PYH1_k127_4602169_11 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000009167 250.0
PYH1_k127_4602169_12 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000502 238.0
PYH1_k127_4602169_13 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000001154 236.0
PYH1_k127_4602169_14 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000002144 219.0
PYH1_k127_4602169_15 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000008353 216.0
PYH1_k127_4602169_16 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000001119 197.0
PYH1_k127_4602169_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000114 194.0
PYH1_k127_4602169_18 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000003917 185.0
PYH1_k127_4602169_19 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000007234 195.0
PYH1_k127_4602169_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 446.0
PYH1_k127_4602169_20 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000004662 175.0
PYH1_k127_4602169_21 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000008445 180.0
PYH1_k127_4602169_22 - - - - 0.0000000000000000000000000000000000000000001052 177.0
PYH1_k127_4602169_23 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000002621 137.0
PYH1_k127_4602169_24 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000003123 145.0
PYH1_k127_4602169_25 copper ion binding K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.000000000000000000000000000000002947 138.0
PYH1_k127_4602169_26 cheY-homologous receiver domain - - - 0.00000000000000000000000000000005596 131.0
PYH1_k127_4602169_27 HEAT repeats - - - 0.0000000000000000000000000000001724 142.0
PYH1_k127_4602169_28 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000021 93.0
PYH1_k127_4602169_29 - - - - 0.0000000000000000003582 96.0
PYH1_k127_4602169_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
PYH1_k127_4602169_30 Protein of unknown function (DUF1622) - - - 0.00000000000000001139 87.0
PYH1_k127_4602169_31 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000001635 85.0
PYH1_k127_4602169_32 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000008636 71.0
PYH1_k127_4602169_33 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000001089 81.0
PYH1_k127_4602169_34 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000752 68.0
PYH1_k127_4602169_35 - - - - 0.00000000007786 71.0
PYH1_k127_4602169_36 NusG domain II - - - 0.00000001048 67.0
PYH1_k127_4602169_37 - - - - 0.00000004833 63.0
PYH1_k127_4602169_38 deoxyhypusine monooxygenase activity - - - 0.000009376 56.0
PYH1_k127_4602169_4 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 419.0
PYH1_k127_4602169_5 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 387.0
PYH1_k127_4602169_6 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 371.0
PYH1_k127_4602169_7 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 365.0
PYH1_k127_4602169_8 S4 RNA-binding domain K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 306.0
PYH1_k127_4602169_9 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002112 279.0
PYH1_k127_4634753_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
PYH1_k127_4634753_1 Tetratricopeptide repeat - - - 0.000000000000001778 88.0
PYH1_k127_4676450_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 325.0
PYH1_k127_4676450_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000003634 216.0
PYH1_k127_4676450_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000003947 87.0
PYH1_k127_4681471_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 510.0
PYH1_k127_4681471_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 515.0
PYH1_k127_4681471_10 - - - - 0.000000000000000000000000000000000000000000000000001537 189.0
PYH1_k127_4681471_11 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000001363 175.0
PYH1_k127_4681471_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000001329 143.0
PYH1_k127_4681471_13 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000007015 124.0
PYH1_k127_4681471_14 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000009017 128.0
PYH1_k127_4681471_15 SPTR CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000000000001474 116.0
PYH1_k127_4681471_16 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000008966 114.0
PYH1_k127_4681471_17 - - - - 0.000000000000000002941 90.0
PYH1_k127_4681471_19 RDD family - - - 0.000000001403 64.0
PYH1_k127_4681471_2 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 503.0
PYH1_k127_4681471_20 - - - - 0.00002251 52.0
PYH1_k127_4681471_3 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 477.0
PYH1_k127_4681471_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 449.0
PYH1_k127_4681471_5 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008962 381.0
PYH1_k127_4681471_6 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
PYH1_k127_4681471_7 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 321.0
PYH1_k127_4681471_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009318 284.0
PYH1_k127_4681471_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
PYH1_k127_4685169_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 490.0
PYH1_k127_4685169_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 368.0
PYH1_k127_4685169_10 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000001555 188.0
PYH1_k127_4685169_11 - - - - 0.0000000000000000000000000000000000000001263 151.0
PYH1_k127_4685169_12 - - - - 0.000000000000000000000000000000000000721 141.0
PYH1_k127_4685169_13 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000007685 146.0
PYH1_k127_4685169_14 - - - - 0.00000000000000000000000000001185 123.0
PYH1_k127_4685169_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000003992 129.0
PYH1_k127_4685169_16 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000001983 121.0
PYH1_k127_4685169_17 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.000000000000000003513 98.0
PYH1_k127_4685169_18 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000002274 90.0
PYH1_k127_4685169_19 - - - - 0.00000000000005654 72.0
PYH1_k127_4685169_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
PYH1_k127_4685169_20 COG NOG14552 non supervised orthologous group - - - 0.00000000002794 63.0
PYH1_k127_4685169_21 Bacterial regulatory proteins, crp family K10914 - - 0.00000000007033 68.0
PYH1_k127_4685169_22 Biopolymer transport protein ExbD/TolR - - - 0.000000000323 68.0
PYH1_k127_4685169_23 - - - - 0.000000001513 59.0
PYH1_k127_4685169_24 TPR repeat - - - 0.000000009711 68.0
PYH1_k127_4685169_25 iron ion homeostasis - - - 0.00002146 55.0
PYH1_k127_4685169_26 OmpA family - - - 0.00002407 57.0
PYH1_k127_4685169_27 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.00004236 55.0
PYH1_k127_4685169_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 338.0
PYH1_k127_4685169_4 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 336.0
PYH1_k127_4685169_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 308.0
PYH1_k127_4685169_6 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000005731 207.0
PYH1_k127_4685169_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000000000008121 204.0
PYH1_k127_4685169_8 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000002212 184.0
PYH1_k127_4685169_9 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000002242 186.0
PYH1_k127_470288_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 580.0
PYH1_k127_470288_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 521.0
PYH1_k127_470288_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 392.0
PYH1_k127_470288_11 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 359.0
PYH1_k127_470288_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 362.0
PYH1_k127_470288_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 342.0
PYH1_k127_470288_14 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 322.0
PYH1_k127_470288_15 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
PYH1_k127_470288_16 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005508 281.0
PYH1_k127_470288_17 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001628 270.0
PYH1_k127_470288_18 SMART CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008659 267.0
PYH1_k127_470288_19 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000084 258.0
PYH1_k127_470288_2 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 488.0
PYH1_k127_470288_20 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
PYH1_k127_470288_21 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
PYH1_k127_470288_22 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
PYH1_k127_470288_23 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000009127 240.0
PYH1_k127_470288_24 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
PYH1_k127_470288_25 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000001268 238.0
PYH1_k127_470288_26 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000003535 216.0
PYH1_k127_470288_27 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000002424 198.0
PYH1_k127_470288_28 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000004078 172.0
PYH1_k127_470288_29 PilZ domain - - - 0.0000000000000000000000000000000000002132 149.0
PYH1_k127_470288_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 471.0
PYH1_k127_470288_30 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000003716 143.0
PYH1_k127_470288_31 Yqey-like protein K09117 - - 0.000000000000000000000000000000000002637 143.0
PYH1_k127_470288_32 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000001849 143.0
PYH1_k127_470288_33 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000002377 128.0
PYH1_k127_470288_34 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000006383 117.0
PYH1_k127_470288_35 - - - - 0.00000000000000000000004906 102.0
PYH1_k127_470288_36 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001188 88.0
PYH1_k127_470288_37 50S ribosomal protein L31 K02909 - - 0.0000000000001466 70.0
PYH1_k127_470288_38 - - - - 0.0000001573 61.0
PYH1_k127_470288_39 Forms part of a two-component regulatory system AfsQ1 AfsQ2 involved in secondary metabolism - - - 0.0000008848 60.0
PYH1_k127_470288_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 461.0
PYH1_k127_470288_40 LppC putative lipoprotein - - - 0.0000418 49.0
PYH1_k127_470288_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 438.0
PYH1_k127_470288_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 438.0
PYH1_k127_470288_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
PYH1_k127_470288_8 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 398.0
PYH1_k127_470288_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 392.0
PYH1_k127_4778351_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 544.0
PYH1_k127_4778351_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 447.0
PYH1_k127_4778351_10 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000004601 213.0
PYH1_k127_4778351_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 421.0
PYH1_k127_4778351_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 413.0
PYH1_k127_4778351_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 360.0
PYH1_k127_4778351_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 316.0
PYH1_k127_4778351_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
PYH1_k127_4778351_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000009672 292.0
PYH1_k127_4778351_8 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003086 259.0
PYH1_k127_4778351_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000003545 256.0
PYH1_k127_4791005_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 402.0
PYH1_k127_4791005_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000003664 142.0
PYH1_k127_4791005_2 - - - - 0.0001033 54.0
PYH1_k127_479595_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.475e-265 831.0
PYH1_k127_479595_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 299.0
PYH1_k127_479595_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002899 272.0
PYH1_k127_479595_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000003558 199.0
PYH1_k127_479595_4 PFAM FMN-binding domain - - - 0.000000000000000000000000000000000000000000000000006048 192.0
PYH1_k127_479595_5 Helix-turn-helix domain - - - 0.000000000000000001215 95.0
PYH1_k127_479595_6 DUF218 domain - - - 0.000000000000002189 87.0
PYH1_k127_479595_8 - - - - 0.000002271 54.0
PYH1_k127_4850671_0 DNA polymerase A domain K02335 - 2.7.7.7 6.059e-274 871.0
PYH1_k127_4850671_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.439e-212 698.0
PYH1_k127_4850671_10 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000004623 211.0
PYH1_k127_4850671_11 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000001213 216.0
PYH1_k127_4850671_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000004118 196.0
PYH1_k127_4850671_13 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000003578 109.0
PYH1_k127_4850671_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP - - - 0.000000000000002056 84.0
PYH1_k127_4850671_15 peptidyl-tyrosine sulfation - - - 0.00000002656 66.0
PYH1_k127_4850671_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 563.0
PYH1_k127_4850671_3 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 491.0
PYH1_k127_4850671_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 422.0
PYH1_k127_4850671_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 398.0
PYH1_k127_4850671_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 381.0
PYH1_k127_4850671_7 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 365.0
PYH1_k127_4850671_8 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 254.0
PYH1_k127_4850671_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.000000000000000000000000000000000000000000000000000000000000000000398 239.0
PYH1_k127_4860705_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1055.0
PYH1_k127_4860705_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 4.047e-249 789.0
PYH1_k127_4860705_10 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000006827 94.0
PYH1_k127_4860705_11 - - - - 0.000000000000001318 79.0
PYH1_k127_4860705_12 Flavodoxin domain - - - 0.000001864 56.0
PYH1_k127_4860705_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 543.0
PYH1_k127_4860705_3 PFAM YeeE YedE family (DUF395) K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 481.0
PYH1_k127_4860705_4 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 432.0
PYH1_k127_4860705_5 acetyl-CoA carboxylase, biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000003749 168.0
PYH1_k127_4860705_6 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000001552 182.0
PYH1_k127_4860705_7 Peptidase family M23 - - - 0.000000000000000000000000000000000000000008192 166.0
PYH1_k127_4860705_8 Cold-shock protein - - - 0.0000000000000000000000008736 104.0
PYH1_k127_4860705_9 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000007058 97.0
PYH1_k127_4900727_0 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000001377 111.0
PYH1_k127_4900727_1 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000003401 80.0
PYH1_k127_4945192_0 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 317.0
PYH1_k127_4945192_1 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000234 151.0
PYH1_k127_4945192_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000004668 140.0
PYH1_k127_4945192_3 anaphase-promoting complex binding - - - 0.00003126 50.0
PYH1_k127_4957289_0 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000000000000000000000000000000000000000000000000001629 205.0
PYH1_k127_4957289_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000002532 202.0
PYH1_k127_4987861_0 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 3.851e-208 666.0
PYH1_k127_4987861_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 511.0
PYH1_k127_4987861_10 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000005418 118.0
PYH1_k127_4987861_11 Preprotein translocase subunit K03210 - - 0.00000000000000000000001579 103.0
PYH1_k127_4987861_12 ATP-binding region ATPase domain protein - - - 0.000007569 58.0
PYH1_k127_4987861_2 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 488.0
PYH1_k127_4987861_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 430.0
PYH1_k127_4987861_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 333.0
PYH1_k127_4987861_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 329.0
PYH1_k127_4987861_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004902 285.0
PYH1_k127_4987861_7 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000001478 224.0
PYH1_k127_4987861_8 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000001767 210.0
PYH1_k127_4987861_9 response regulator - - - 0.000000000000000000000000000000501 127.0
PYH1_k127_5106246_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 536.0
PYH1_k127_5106246_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
PYH1_k127_5106246_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000001642 195.0
PYH1_k127_5106246_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000297 145.0
PYH1_k127_5106246_4 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.0000000000000008665 91.0
PYH1_k127_511160_0 Threonine synthase K01733 - 4.2.3.1 1.603e-197 636.0
PYH1_k127_511160_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 559.0
PYH1_k127_511160_2 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 464.0
PYH1_k127_511160_3 PFAM Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
PYH1_k127_511160_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000001899 194.0
PYH1_k127_511160_5 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000003042 158.0
PYH1_k127_511160_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000001087 139.0
PYH1_k127_511160_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.0000000000002072 74.0
PYH1_k127_5125896_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 565.0
PYH1_k127_5125896_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000001592 126.0
PYH1_k127_5221648_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1682.0
PYH1_k127_5221648_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 3.534e-313 989.0
PYH1_k127_5221648_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 501.0
PYH1_k127_5221648_11 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 504.0
PYH1_k127_5221648_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 393.0
PYH1_k127_5221648_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 392.0
PYH1_k127_5221648_14 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
PYH1_k127_5221648_15 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 343.0
PYH1_k127_5221648_16 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 342.0
PYH1_k127_5221648_17 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 353.0
PYH1_k127_5221648_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
PYH1_k127_5221648_19 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
PYH1_k127_5221648_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.287e-261 851.0
PYH1_k127_5221648_20 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 297.0
PYH1_k127_5221648_21 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 293.0
PYH1_k127_5221648_22 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006195 280.0
PYH1_k127_5221648_23 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002887 276.0
PYH1_k127_5221648_24 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003007 292.0
PYH1_k127_5221648_25 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 270.0
PYH1_k127_5221648_26 anaerobic respiration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001264 275.0
PYH1_k127_5221648_27 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
PYH1_k127_5221648_28 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001301 258.0
PYH1_k127_5221648_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002192 256.0
PYH1_k127_5221648_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 2.221e-240 757.0
PYH1_k127_5221648_30 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000004628 266.0
PYH1_k127_5221648_31 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
PYH1_k127_5221648_32 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
PYH1_k127_5221648_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002471 225.0
PYH1_k127_5221648_34 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000001677 213.0
PYH1_k127_5221648_35 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000108 206.0
PYH1_k127_5221648_36 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000001197 213.0
PYH1_k127_5221648_37 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
PYH1_k127_5221648_38 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000004806 206.0
PYH1_k127_5221648_39 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000003684 194.0
PYH1_k127_5221648_4 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.979e-210 672.0
PYH1_k127_5221648_40 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000005005 195.0
PYH1_k127_5221648_41 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001685 189.0
PYH1_k127_5221648_42 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000006994 190.0
PYH1_k127_5221648_43 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000001452 189.0
PYH1_k127_5221648_44 - - - - 0.0000000000000000000000000000000000000000000005936 179.0
PYH1_k127_5221648_45 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000005897 167.0
PYH1_k127_5221648_46 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K01256,K02563,K02652,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.0000000000000000000000000000000000000000000149 178.0
PYH1_k127_5221648_47 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000004647 173.0
PYH1_k127_5221648_48 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000392 160.0
PYH1_k127_5221648_49 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000001386 165.0
PYH1_k127_5221648_5 TIGRFAM formate dehydrogenase, alpha subunit K00123,K00336,K05299 - 1.17.1.10,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 626.0
PYH1_k127_5221648_50 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000001913 161.0
PYH1_k127_5221648_51 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000003035 149.0
PYH1_k127_5221648_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000007698 141.0
PYH1_k127_5221648_53 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000002206 134.0
PYH1_k127_5221648_54 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000007881 126.0
PYH1_k127_5221648_55 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000008037 130.0
PYH1_k127_5221648_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000004621 118.0
PYH1_k127_5221648_57 Belongs to the P(II) protein family - - - 0.0000000000000000000000002129 109.0
PYH1_k127_5221648_58 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.0000000000000000000009574 107.0
PYH1_k127_5221648_59 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000003173 92.0
PYH1_k127_5221648_6 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 580.0
PYH1_k127_5221648_60 Tetratricopeptide repeat - - - 0.000000000000002014 91.0
PYH1_k127_5221648_61 - - - - 0.0000000000003428 75.0
PYH1_k127_5221648_62 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.00000000001654 68.0
PYH1_k127_5221648_63 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000005743 69.0
PYH1_k127_5221648_64 PFAM RNA-binding S4 domain protein - - - 0.00000000007033 68.0
PYH1_k127_5221648_65 PilZ domain - - - 0.0000000007749 64.0
PYH1_k127_5221648_66 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000002713 57.0
PYH1_k127_5221648_67 Pentapeptide repeats (9 copies) - - - 0.0001606 53.0
PYH1_k127_5221648_7 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 554.0
PYH1_k127_5221648_8 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 561.0
PYH1_k127_5221648_9 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 538.0
PYH1_k127_5285631_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1112.0
PYH1_k127_5285631_1 response regulator K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 535.0
PYH1_k127_5285631_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000005687 215.0
PYH1_k127_5285631_3 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000002885 167.0
PYH1_k127_5285631_4 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000004752 94.0
PYH1_k127_5285631_5 Protein of unknown function DUF116 - - - 0.000000000006537 75.0
PYH1_k127_5285631_6 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.000000000008377 75.0
PYH1_k127_5344877_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 356.0
PYH1_k127_5344877_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008813 280.0
PYH1_k127_553257_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1092.0
PYH1_k127_553257_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.429e-226 719.0
PYH1_k127_553257_10 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
PYH1_k127_553257_11 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
PYH1_k127_553257_12 Formate dehydrogenase N, transmembrane K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
PYH1_k127_553257_13 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
PYH1_k127_553257_14 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001876 235.0
PYH1_k127_553257_15 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000008472 245.0
PYH1_k127_553257_16 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
PYH1_k127_553257_17 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.000000000000000000000000000000000000000000000888 169.0
PYH1_k127_553257_18 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000005776 167.0
PYH1_k127_553257_19 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000009843 177.0
PYH1_k127_553257_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 590.0
PYH1_k127_553257_20 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000001642 143.0
PYH1_k127_553257_21 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000004585 122.0
PYH1_k127_553257_22 DNA-binding transcription factor activity K03892 - - 0.00000000000000003888 94.0
PYH1_k127_553257_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000005509 88.0
PYH1_k127_553257_24 Putative regulatory protein - - - 0.00000000000457 68.0
PYH1_k127_553257_25 RNA-binding protein - - - 0.0000004006 56.0
PYH1_k127_553257_26 Transcriptional regulator - - - 0.0001792 48.0
PYH1_k127_553257_3 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 530.0
PYH1_k127_553257_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 447.0
PYH1_k127_553257_5 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 435.0
PYH1_k127_553257_6 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
PYH1_k127_553257_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 385.0
PYH1_k127_553257_8 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 365.0
PYH1_k127_553257_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 327.0
PYH1_k127_5692439_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000238 256.0
PYH1_k127_5692439_1 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000001778 136.0
PYH1_k127_5692439_2 DivIVA protein K04074 - - 0.0000000000000000000000000000000001811 138.0
PYH1_k127_5692439_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000002839 82.0
PYH1_k127_5692439_4 Belongs to the UPF0235 family K09131 - - 0.0000000000000001502 85.0
PYH1_k127_5692439_5 YGGT family K02221 - - 0.00000000000003517 76.0
PYH1_k127_5692439_6 Kelch motif - - - 0.000000000000887 81.0
PYH1_k127_5692439_7 Peptidase MA superfamily - - - 0.000000001767 70.0
PYH1_k127_5692439_8 PEGA domain - - - 0.00002038 57.0
PYH1_k127_5727422_0 response regulator - - - 9.88e-204 644.0
PYH1_k127_5727422_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 567.0
PYH1_k127_5727422_10 - - - - 0.000000000000000000000000000004911 125.0
PYH1_k127_5727422_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000003567 99.0
PYH1_k127_5727422_12 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000003316 67.0
PYH1_k127_5727422_13 - - - - 0.0000007855 53.0
PYH1_k127_5727422_2 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 466.0
PYH1_k127_5727422_3 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 475.0
PYH1_k127_5727422_4 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 376.0
PYH1_k127_5727422_5 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 375.0
PYH1_k127_5727422_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 357.0
PYH1_k127_5727422_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
PYH1_k127_5727422_8 Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000006697 186.0
PYH1_k127_5727422_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000008144 151.0
PYH1_k127_5788458_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 605.0
PYH1_k127_5788458_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 465.0
PYH1_k127_5788458_2 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 460.0
PYH1_k127_5788458_3 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 342.0
PYH1_k127_5788458_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 329.0
PYH1_k127_5788458_5 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
PYH1_k127_5788458_6 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 321.0
PYH1_k127_5788458_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000002467 169.0
PYH1_k127_5788458_8 Thioredoxin-like - - - 0.00000000000000000000000000000000000007407 156.0
PYH1_k127_5788458_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000005806 104.0
PYH1_k127_578887_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 538.0
PYH1_k127_578887_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 401.0
PYH1_k127_578887_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 325.0
PYH1_k127_578887_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000005437 196.0
PYH1_k127_578887_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000004599 174.0
PYH1_k127_578887_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000006093 126.0
PYH1_k127_578887_6 Essential cell division protein K03589 - - 0.0000000000007126 79.0
PYH1_k127_586944_0 PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000001302 208.0
PYH1_k127_586944_1 TPR repeat-containing protein - - - 0.0000000000000000000000005261 115.0
PYH1_k127_586944_2 - - - - 0.000000000000000000000246 103.0
PYH1_k127_5875026_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1329.0
PYH1_k127_5875026_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.562e-262 824.0
PYH1_k127_5875026_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 354.0
PYH1_k127_5875026_11 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 337.0
PYH1_k127_5875026_12 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 340.0
PYH1_k127_5875026_13 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 316.0
PYH1_k127_5875026_14 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 312.0
PYH1_k127_5875026_15 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 293.0
PYH1_k127_5875026_16 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002766 283.0
PYH1_k127_5875026_17 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 288.0
PYH1_k127_5875026_18 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004546 291.0
PYH1_k127_5875026_19 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006478 272.0
PYH1_k127_5875026_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.478e-216 692.0
PYH1_k127_5875026_20 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000002093 241.0
PYH1_k127_5875026_21 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000004961 218.0
PYH1_k127_5875026_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000011 202.0
PYH1_k127_5875026_23 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000007682 199.0
PYH1_k127_5875026_24 DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000004583 194.0
PYH1_k127_5875026_25 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000063 185.0
PYH1_k127_5875026_26 TIGR00255 family - - - 0.0000000000000000000000000000000000000000000000007932 185.0
PYH1_k127_5875026_27 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000001337 171.0
PYH1_k127_5875026_28 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000006109 179.0
PYH1_k127_5875026_29 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000001992 172.0
PYH1_k127_5875026_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.636e-214 677.0
PYH1_k127_5875026_30 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000007665 148.0
PYH1_k127_5875026_31 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000001756 154.0
PYH1_k127_5875026_32 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000388 152.0
PYH1_k127_5875026_33 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000001243 138.0
PYH1_k127_5875026_34 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000004779 131.0
PYH1_k127_5875026_35 regulation of translation K05788 - - 0.000000000000000000000000000009136 121.0
PYH1_k127_5875026_36 Tetratricopeptide repeat - - - 0.0000000000000000000000001162 119.0
PYH1_k127_5875026_37 - - - - 0.000000000000000000000002585 119.0
PYH1_k127_5875026_38 oligosaccharyl transferase activity - - - 0.00000000000000000000003006 115.0
PYH1_k127_5875026_39 peroxiredoxin activity - - - 0.00000000000000000000006685 113.0
PYH1_k127_5875026_4 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 625.0
PYH1_k127_5875026_40 phosphorelay signal transduction system - - - 0.000000000000000000004299 110.0
PYH1_k127_5875026_41 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000004316 90.0
PYH1_k127_5875026_42 Recombination protein O C terminal K03584 - - 0.00000000000000004356 95.0
PYH1_k127_5875026_43 response regulator, receiver K03413 - - 0.00000000000000009307 95.0
PYH1_k127_5875026_45 Domain of unknown function (DUF4115) - - - 0.00000000000005385 83.0
PYH1_k127_5875026_46 - - - - 0.0000000000001147 75.0
PYH1_k127_5875026_48 photosynthesis K02453,K02660 - - 0.00000001103 67.0
PYH1_k127_5875026_49 PFAM Chorismate mutase, type II - - - 0.0000004229 57.0
PYH1_k127_5875026_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 608.0
PYH1_k127_5875026_50 Tetratricopeptide repeat - - - 0.000002371 57.0
PYH1_k127_5875026_51 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00002552 51.0
PYH1_k127_5875026_52 - - - - 0.00005459 55.0
PYH1_k127_5875026_53 Cytochrome c - - - 0.0005687 47.0
PYH1_k127_5875026_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 511.0
PYH1_k127_5875026_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 454.0
PYH1_k127_5875026_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 444.0
PYH1_k127_5875026_9 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 426.0
PYH1_k127_5889745_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.275e-202 637.0
PYH1_k127_5889745_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 392.0
PYH1_k127_5889745_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001401 193.0
PYH1_k127_5889745_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003738 192.0
PYH1_k127_5889745_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000008165 177.0
PYH1_k127_5889745_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000007442 171.0
PYH1_k127_5889745_14 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000008362 164.0
PYH1_k127_5889745_15 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002266 156.0
PYH1_k127_5889745_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000001507 144.0
PYH1_k127_5889745_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000001958 131.0
PYH1_k127_5889745_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000001198 109.0
PYH1_k127_5889745_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005591 104.0
PYH1_k127_5889745_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 387.0
PYH1_k127_5889745_20 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001785 70.0
PYH1_k127_5889745_21 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001058 75.0
PYH1_k127_5889745_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 295.0
PYH1_k127_5889745_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
PYH1_k127_5889745_5 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 292.0
PYH1_k127_5889745_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
PYH1_k127_5889745_7 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000008947 239.0
PYH1_k127_5889745_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000004109 212.0
PYH1_k127_5889745_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000002551 201.0
PYH1_k127_5894063_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.701e-226 733.0
PYH1_k127_5894063_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 446.0
PYH1_k127_5894063_10 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
PYH1_k127_5894063_11 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000005325 145.0
PYH1_k127_5894063_12 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000000005059 140.0
PYH1_k127_5894063_13 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000007746 132.0
PYH1_k127_5894063_14 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.000000000000000000000000000005512 128.0
PYH1_k127_5894063_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 418.0
PYH1_k127_5894063_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 394.0
PYH1_k127_5894063_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 402.0
PYH1_k127_5894063_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 362.0
PYH1_k127_5894063_6 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 366.0
PYH1_k127_5894063_7 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 347.0
PYH1_k127_5894063_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 297.0
PYH1_k127_5894063_9 cheY-homologous receiver domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
PYH1_k127_5894073_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1566.0
PYH1_k127_5894073_1 COG0058 Glucan phosphorylase - - - 7.112e-242 760.0
PYH1_k127_5894073_10 Psort location Extracellular, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001188 231.0
PYH1_k127_5894073_11 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000246 228.0
PYH1_k127_5894073_12 TIGRFAM ABC-2 type transporter, NodJ K09694 - - 0.00000000000000000000000000000000000000000000000000000000000009734 229.0
PYH1_k127_5894073_13 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000001056 219.0
PYH1_k127_5894073_14 NosL - - - 0.00000000000000000000000000000000000000000000000002279 184.0
PYH1_k127_5894073_15 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000008245 178.0
PYH1_k127_5894073_16 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000000006215 169.0
PYH1_k127_5894073_17 PFAM NosL family protein - - - 0.0000000000000000000000000000000000001736 150.0
PYH1_k127_5894073_18 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000008609 138.0
PYH1_k127_5894073_19 GYD domain - - - 0.0000000000000000000000008819 118.0
PYH1_k127_5894073_2 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 568.0
PYH1_k127_5894073_20 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000002954 117.0
PYH1_k127_5894073_21 Thioredoxin-like - - - 0.000000000000000000000003103 109.0
PYH1_k127_5894073_22 TPR repeat-containing protein - - - 0.000000000000000000000006507 114.0
PYH1_k127_5894073_23 - - - - 0.00000000000000000000003533 102.0
PYH1_k127_5894073_24 translation initiation factor activity K03646 - - 0.000000000000002424 89.0
PYH1_k127_5894073_25 Membrane - - - 0.00000000000002925 81.0
PYH1_k127_5894073_26 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000006346 75.0
PYH1_k127_5894073_27 - - - - 0.000000001244 72.0
PYH1_k127_5894073_28 - - - - 0.00000008232 65.0
PYH1_k127_5894073_29 Tetratricopeptide repeat - - - 0.0000009822 61.0
PYH1_k127_5894073_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 441.0
PYH1_k127_5894073_30 oxidoreductase activity - - - 0.000001296 61.0
PYH1_k127_5894073_31 - - - - 0.000001995 50.0
PYH1_k127_5894073_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 363.0
PYH1_k127_5894073_5 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 341.0
PYH1_k127_5894073_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 328.0
PYH1_k127_5894073_7 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 322.0
PYH1_k127_5894073_8 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 312.0
PYH1_k127_5894073_9 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
PYH1_k127_5906512_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 532.0
PYH1_k127_5906512_1 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 297.0
PYH1_k127_5906512_10 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000001137 105.0
PYH1_k127_5906512_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
PYH1_k127_5906512_3 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
PYH1_k127_5906512_4 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
PYH1_k127_5906512_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000009428 197.0
PYH1_k127_5906512_6 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000008548 190.0
PYH1_k127_5906512_7 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000004742 162.0
PYH1_k127_5906512_8 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000000000007497 163.0
PYH1_k127_5906512_9 Belongs to the peptidase S8 family - - - 0.000000000000000000000000001074 129.0
PYH1_k127_5907242_0 alginic acid biosynthetic process K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003157 279.0
PYH1_k127_5907242_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000002338 229.0
PYH1_k127_5907242_2 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000002908 196.0
PYH1_k127_5907242_3 oligosaccharyl transferase activity - - - 0.00000000000000000000000006282 124.0
PYH1_k127_5907242_4 alginic acid biosynthetic process - - - 0.0000000000000000002211 104.0
PYH1_k127_5907242_5 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000002263 81.0
PYH1_k127_5907242_6 OmpA-like transmembrane domain - - - 0.0000001251 60.0
PYH1_k127_5925223_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 608.0
PYH1_k127_5925223_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 518.0
PYH1_k127_5925223_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
PYH1_k127_5925223_3 beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003613 276.0
PYH1_k127_5925223_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000009027 245.0
PYH1_k127_5925223_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000005324 78.0
PYH1_k127_5925223_6 - - - - 0.00000001969 67.0
PYH1_k127_5980573_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.651e-294 923.0
PYH1_k127_5980573_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 316.0
PYH1_k127_5980573_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001033 288.0
PYH1_k127_5980573_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000286 278.0
PYH1_k127_5980573_4 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000433 198.0
PYH1_k127_5980573_5 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000005641 177.0
PYH1_k127_6138975_0 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 561.0
PYH1_k127_6138975_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 364.0
PYH1_k127_6138975_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 302.0
PYH1_k127_6138975_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000009054 71.0
PYH1_k127_6150941_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 482.0
PYH1_k127_6150941_1 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 313.0
PYH1_k127_6150941_2 THIoesterase K18700 - 3.1.2.29 0.00000000000000002305 89.0
PYH1_k127_6155038_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1100.0
PYH1_k127_6155038_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.143e-300 949.0
PYH1_k127_6155038_10 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.00000000000000000000000003068 126.0
PYH1_k127_6155038_11 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000006134 110.0
PYH1_k127_6155038_12 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000001539 92.0
PYH1_k127_6155038_13 Hsp20/alpha crystallin family K13993 - - 0.0000000000000001633 87.0
PYH1_k127_6155038_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0006768 50.0
PYH1_k127_6155038_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 473.0
PYH1_k127_6155038_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 443.0
PYH1_k127_6155038_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
PYH1_k127_6155038_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 301.0
PYH1_k127_6155038_6 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000002409 203.0
PYH1_k127_6155038_7 TPR repeat - - - 0.0000000000000000000000000000000000000000000000001185 195.0
PYH1_k127_6155038_8 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000007177 144.0
PYH1_k127_6155038_9 Lysin motif - - - 0.000000000000000000000000000000000000913 153.0
PYH1_k127_6231239_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 396.0
PYH1_k127_6231239_1 TIGRFAM C_GCAxxG_C_C family - - - 0.000000000000004443 81.0
PYH1_k127_6231239_2 GDYXXLXY protein - - - 0.000000003662 60.0
PYH1_k127_6327841_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 509.0
PYH1_k127_6327841_1 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007452 282.0
PYH1_k127_6327841_2 Type II secretion system K12510 - - 0.0000000000001337 78.0
PYH1_k127_6327841_3 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000001527 83.0
PYH1_k127_6327841_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000263 52.0
PYH1_k127_6352928_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.38e-311 971.0
PYH1_k127_6352928_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 610.0
PYH1_k127_6352928_10 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000005059 151.0
PYH1_k127_6352928_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000002473 144.0
PYH1_k127_6352928_12 ABC transporter K02006 - - 0.000000000000000000000000000000005468 128.0
PYH1_k127_6352928_13 GIY-YIG catalytic domain - - - 0.00000000000000000000000000003173 121.0
PYH1_k127_6352928_14 Protein of unknown function (DUF2628) - - - 0.00000000000000000000000000046 121.0
PYH1_k127_6352928_15 Protein of unknown function (DUF2628) - - - 0.0000000000000000000009136 102.0
PYH1_k127_6352928_18 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000002025 77.0
PYH1_k127_6352928_19 GIY-YIG catalytic domain K07461 - - 0.00000000106 62.0
PYH1_k127_6352928_2 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 534.0
PYH1_k127_6352928_20 - - - - 0.0000003102 57.0
PYH1_k127_6352928_21 anaerobic respiration - - - 0.000007489 54.0
PYH1_k127_6352928_22 Resolvase, N terminal domain - - - 0.00006785 48.0
PYH1_k127_6352928_3 phosphatidate phosphatase activity K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 402.0
PYH1_k127_6352928_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 295.0
PYH1_k127_6352928_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000004268 255.0
PYH1_k127_6352928_6 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000001045 209.0
PYH1_k127_6352928_7 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000005909 205.0
PYH1_k127_6352928_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000056 199.0
PYH1_k127_6352928_9 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000001775 185.0
PYH1_k127_6380351_0 Elongation factor G C-terminus K06207 - - 4.299e-297 921.0
PYH1_k127_6380351_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.794e-200 642.0
PYH1_k127_6380351_10 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000001203 154.0
PYH1_k127_6380351_11 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000005214 126.0
PYH1_k127_6380351_12 Protein of Unknown function (DUF2784) - - - 0.0000000002632 71.0
PYH1_k127_6380351_13 Tetratricopeptide repeat-like domain - - - 0.000000003013 66.0
PYH1_k127_6380351_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 557.0
PYH1_k127_6380351_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 537.0
PYH1_k127_6380351_4 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 377.0
PYH1_k127_6380351_5 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 368.0
PYH1_k127_6380351_6 GDP-mannose 4,6 dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 353.0
PYH1_k127_6380351_7 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009355 231.0
PYH1_k127_6380351_8 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000004826 192.0
PYH1_k127_6380351_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000001081 188.0
PYH1_k127_6514058_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.388e-207 653.0
PYH1_k127_6514058_1 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 380.0
PYH1_k127_6514058_2 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 313.0
PYH1_k127_6514058_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009061 296.0
PYH1_k127_6566813_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 515.0
PYH1_k127_6578751_0 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006164 295.0
PYH1_k127_6578751_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000189 85.0
PYH1_k127_6578751_2 Protein of unknown function (DUF2934) - - - 0.0000000000001393 74.0
PYH1_k127_6578751_3 Rubrerythrin - - - 0.0000000000006179 77.0
PYH1_k127_6578751_4 PilZ domain - - - 0.0000003712 55.0
PYH1_k127_6578751_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0002039 48.0
PYH1_k127_6592957_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 515.0
PYH1_k127_6592957_1 - - - - 0.00002856 46.0
PYH1_k127_6711703_0 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 482.0
PYH1_k127_6711703_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 462.0
PYH1_k127_6711703_10 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004062 311.0
PYH1_k127_6711703_11 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006296 279.0
PYH1_k127_6711703_12 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002529 278.0
PYH1_k127_6711703_13 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000001447 250.0
PYH1_k127_6711703_14 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003201 244.0
PYH1_k127_6711703_15 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001944 227.0
PYH1_k127_6711703_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000002701 183.0
PYH1_k127_6711703_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000003913 168.0
PYH1_k127_6711703_18 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000004511 162.0
PYH1_k127_6711703_19 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000003863 143.0
PYH1_k127_6711703_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 424.0
PYH1_k127_6711703_20 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000005161 141.0
PYH1_k127_6711703_21 Amidohydrolase - - - 0.0000000000000000000000000004625 123.0
PYH1_k127_6711703_22 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000388 113.0
PYH1_k127_6711703_23 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000005336 109.0
PYH1_k127_6711703_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02487 - - 0.00000000000000000005662 98.0
PYH1_k127_6711703_25 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000006004 87.0
PYH1_k127_6711703_26 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000003498 79.0
PYH1_k127_6711703_27 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00001411 55.0
PYH1_k127_6711703_28 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00005442 57.0
PYH1_k127_6711703_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 406.0
PYH1_k127_6711703_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 392.0
PYH1_k127_6711703_5 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 381.0
PYH1_k127_6711703_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 371.0
PYH1_k127_6711703_7 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 347.0
PYH1_k127_6711703_8 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 350.0
PYH1_k127_6711703_9 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
PYH1_k127_6712933_0 methyltransferase - - - 8.912e-211 664.0
PYH1_k127_6712933_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.878e-210 680.0
PYH1_k127_6712933_10 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 439.0
PYH1_k127_6712933_11 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 402.0
PYH1_k127_6712933_12 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 404.0
PYH1_k127_6712933_13 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 398.0
PYH1_k127_6712933_14 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 394.0
PYH1_k127_6712933_15 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 399.0
PYH1_k127_6712933_16 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
PYH1_k127_6712933_17 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 398.0
PYH1_k127_6712933_18 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 377.0
PYH1_k127_6712933_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 348.0
PYH1_k127_6712933_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 600.0
PYH1_k127_6712933_20 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 334.0
PYH1_k127_6712933_21 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 289.0
PYH1_k127_6712933_22 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
PYH1_k127_6712933_23 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007523 267.0
PYH1_k127_6712933_24 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 261.0
PYH1_k127_6712933_25 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH1_k127_6712933_26 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
PYH1_k127_6712933_27 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001271 250.0
PYH1_k127_6712933_28 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000007469 242.0
PYH1_k127_6712933_29 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008599 243.0
PYH1_k127_6712933_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 601.0
PYH1_k127_6712933_30 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000003256 228.0
PYH1_k127_6712933_31 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000002627 233.0
PYH1_k127_6712933_32 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000005662 212.0
PYH1_k127_6712933_33 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000002359 226.0
PYH1_k127_6712933_34 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000009879 203.0
PYH1_k127_6712933_35 Curli production assembly transport component CsgG K04087 - - 0.000000000000000000000000000000000000000000000000000000308 207.0
PYH1_k127_6712933_36 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000003911 200.0
PYH1_k127_6712933_37 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000002453 190.0
PYH1_k127_6712933_38 - - - - 0.0000000000000000000000000000000000000000000002252 178.0
PYH1_k127_6712933_39 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000006556 174.0
PYH1_k127_6712933_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 592.0
PYH1_k127_6712933_40 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000003397 164.0
PYH1_k127_6712933_41 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000003792 158.0
PYH1_k127_6712933_42 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000001406 151.0
PYH1_k127_6712933_43 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000001373 139.0
PYH1_k127_6712933_44 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000106 136.0
PYH1_k127_6712933_45 lysyltransferase activity K07027 - - 0.000000000000000000000000000000004372 143.0
PYH1_k127_6712933_46 Cytochrome b/b6/petB K03620 - - 0.00000000000000000000000000003634 124.0
PYH1_k127_6712933_47 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000006014 124.0
PYH1_k127_6712933_48 Histidine kinase - - - 0.000000000000000000005344 102.0
PYH1_k127_6712933_49 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000001441 106.0
PYH1_k127_6712933_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 539.0
PYH1_k127_6712933_50 CBS domain K00974 - 2.7.7.72 0.000000000000000000173 95.0
PYH1_k127_6712933_51 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000007135 93.0
PYH1_k127_6712933_52 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000001237 81.0
PYH1_k127_6712933_53 HD domain - - - 0.0000000000000001583 84.0
PYH1_k127_6712933_54 FHA Domain - - - 0.000000000000001543 89.0
PYH1_k127_6712933_55 metal-dependent phosphoesterases (PHP family) - - - 0.000000000003094 75.0
PYH1_k127_6712933_56 Sensor diguanylate cyclase, GAF domain-containing - - - 0.00000000003314 76.0
PYH1_k127_6712933_57 VanZ like family - - - 0.0000006197 60.0
PYH1_k127_6712933_58 Mitochondrial domain of unknown function (DUF1713) - - - 0.00003666 47.0
PYH1_k127_6712933_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 521.0
PYH1_k127_6712933_7 Aldehyde dehydrogenase family K00128,K00131 - 1.2.1.3,1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 445.0
PYH1_k127_6712933_8 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 441.0
PYH1_k127_6712933_9 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 435.0
PYH1_k127_6713073_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.47e-205 649.0
PYH1_k127_6722582_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.585e-290 911.0
PYH1_k127_6722582_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 601.0
PYH1_k127_6722582_10 Roadblock/LC7 domain - - - 0.0000007732 61.0
PYH1_k127_6722582_2 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 565.0
PYH1_k127_6722582_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 281.0
PYH1_k127_6722582_4 PFAM Creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000007949 222.0
PYH1_k127_6722582_5 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000008905 157.0
PYH1_k127_6722582_6 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000003304 157.0
PYH1_k127_6722582_7 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000001574 147.0
PYH1_k127_6722582_8 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000004763 123.0
PYH1_k127_6722582_9 4Fe-4S binding domain - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000003095 93.0
PYH1_k127_6757348_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 483.0
PYH1_k127_6757348_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000003267 133.0
PYH1_k127_6825456_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1045.0
PYH1_k127_6825456_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 498.0
PYH1_k127_6825456_10 TonB-dependent receptor K02014,K02456,K02457,K02458,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.00000000000000859 89.0
PYH1_k127_6825456_12 impB/mucB/samB family K02346 - 2.7.7.7 0.000000000003701 69.0
PYH1_k127_6825456_2 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 425.0
PYH1_k127_6825456_3 HI0933-like protein K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 429.0
PYH1_k127_6825456_4 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 299.0
PYH1_k127_6825456_5 MgtE intracellular N domain K02000,K05847 - 3.6.3.32 0.000000000000000000000000000000000000000000000000001149 205.0
PYH1_k127_6825456_6 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000508 125.0
PYH1_k127_6825456_7 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.0000000000000000000000007749 113.0
PYH1_k127_6825456_8 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000004867 105.0
PYH1_k127_6825456_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000000000001178 109.0
PYH1_k127_6836172_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 5.067e-237 748.0
PYH1_k127_6836172_1 Dehydratase family K01687 - 4.2.1.9 2.855e-216 686.0
PYH1_k127_6836172_10 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000492 260.0
PYH1_k127_6836172_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000005049 240.0
PYH1_k127_6836172_12 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001933 219.0
PYH1_k127_6836172_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000005268 213.0
PYH1_k127_6836172_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000009464 179.0
PYH1_k127_6836172_15 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000004312 187.0
PYH1_k127_6836172_16 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000001344 165.0
PYH1_k127_6836172_17 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000007314 133.0
PYH1_k127_6836172_18 - - - - 0.00000000000000000000000000002567 133.0
PYH1_k127_6836172_19 glycoprotease K14742 - - 0.00000000000000000000002573 114.0
PYH1_k127_6836172_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.26e-202 640.0
PYH1_k127_6836172_20 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000001087 71.0
PYH1_k127_6836172_21 Protein of unknown function (DUF465) K09794 - - 0.0000001111 55.0
PYH1_k127_6836172_22 - - - - 0.0000001845 61.0
PYH1_k127_6836172_23 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000001848 56.0
PYH1_k127_6836172_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 605.0
PYH1_k127_6836172_4 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 541.0
PYH1_k127_6836172_5 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 442.0
PYH1_k127_6836172_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 440.0
PYH1_k127_6836172_7 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 426.0
PYH1_k127_6836172_8 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 413.0
PYH1_k127_6836172_9 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 407.0
PYH1_k127_6878363_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.679e-243 770.0
PYH1_k127_6878363_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.163e-215 699.0
PYH1_k127_6878363_10 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000001993 95.0
PYH1_k127_6878363_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000004446 97.0
PYH1_k127_6878363_12 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.0000000000000000005937 94.0
PYH1_k127_6878363_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 457.0
PYH1_k127_6878363_3 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 384.0
PYH1_k127_6878363_4 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 294.0
PYH1_k127_6878363_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000005274 216.0
PYH1_k127_6878363_6 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000396 186.0
PYH1_k127_6878363_7 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000003074 147.0
PYH1_k127_6878363_8 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000003814 137.0
PYH1_k127_6878363_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001891 127.0
PYH1_k127_6915868_0 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
PYH1_k127_6915868_1 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000006647 125.0
PYH1_k127_692034_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001461 209.0
PYH1_k127_692034_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000002335 190.0
PYH1_k127_692034_2 regulator - - - 0.0000000000000000000000000000000000000000000000001412 201.0
PYH1_k127_692034_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000003972 184.0
PYH1_k127_692034_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000004145 198.0
PYH1_k127_692034_5 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000001507 115.0
PYH1_k127_6932144_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 514.0
PYH1_k127_6932144_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 439.0
PYH1_k127_6932144_10 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000006575 189.0
PYH1_k127_6932144_11 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000001272 173.0
PYH1_k127_6932144_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000004662 166.0
PYH1_k127_6932144_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000183 162.0
PYH1_k127_6932144_14 Could be involved in septation K06412 - - 0.00000000000000000000000000000001653 136.0
PYH1_k127_6932144_15 - - - - 0.0000000000000000000000003879 109.0
PYH1_k127_6932144_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000159 53.0
PYH1_k127_6932144_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 419.0
PYH1_k127_6932144_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 331.0
PYH1_k127_6932144_4 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 311.0
PYH1_k127_6932144_5 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
PYH1_k127_6932144_6 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000003628 246.0
PYH1_k127_6932144_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000005376 203.0
PYH1_k127_6932144_8 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000482 203.0
PYH1_k127_6932144_9 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000001586 192.0
PYH1_k127_6972650_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 593.0
PYH1_k127_6972650_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 409.0
PYH1_k127_6972650_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 390.0
PYH1_k127_6972650_3 Domain of unknown function (DUF4912) K09942 - - 0.000000007189 66.0
PYH1_k127_6988406_0 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 396.0
PYH1_k127_6988406_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
PYH1_k127_6988406_2 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001219 287.0
PYH1_k127_7028827_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.837e-251 787.0
PYH1_k127_7028827_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 607.0
PYH1_k127_7028827_10 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 364.0
PYH1_k127_7028827_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 362.0
PYH1_k127_7028827_12 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
PYH1_k127_7028827_13 - K03616 - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
PYH1_k127_7028827_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
PYH1_k127_7028827_15 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000074 190.0
PYH1_k127_7028827_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000004803 185.0
PYH1_k127_7028827_17 TIGRFAM Addiction module antidote protein - - - 0.00000000000000000000000000000000000000000000115 166.0
PYH1_k127_7028827_18 addiction module killer protein - - - 0.000000000000000000000000000000000000004576 147.0
PYH1_k127_7028827_19 beta-propeller repeat - - - 0.0000000000000000000000000000000000007358 156.0
PYH1_k127_7028827_2 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 595.0
PYH1_k127_7028827_20 Flagellar hook protein flgE - - - 0.000000000000000000000000000002854 140.0
PYH1_k127_7028827_21 Transporter, MotA TolQ ExbB proton channel family protein K03561 - - 0.0000000000000000000000000002846 122.0
PYH1_k127_7028827_22 protein kinase related protein - - - 0.000000000000000000000001837 119.0
PYH1_k127_7028827_23 Tetratricopeptide repeat - - - 0.00000000000000000000000335 119.0
PYH1_k127_7028827_24 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000005589 99.0
PYH1_k127_7028827_25 Response regulator receiver K02485 - - 0.000000000000008687 81.0
PYH1_k127_7028827_26 Tetratricopeptide repeat - - - 0.000000000009416 78.0
PYH1_k127_7028827_27 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000001651 74.0
PYH1_k127_7028827_28 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000002735 61.0
PYH1_k127_7028827_29 Tetratricopeptide repeat - - - 0.000001078 62.0
PYH1_k127_7028827_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 523.0
PYH1_k127_7028827_30 toxin-antitoxin pair type II binding - - - 0.0009014 46.0
PYH1_k127_7028827_4 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 507.0
PYH1_k127_7028827_5 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
PYH1_k127_7028827_6 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 463.0
PYH1_k127_7028827_7 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 434.0
PYH1_k127_7028827_8 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 419.0
PYH1_k127_7028827_9 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 391.0
PYH1_k127_7065526_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 476.0
PYH1_k127_7065526_1 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 442.0
PYH1_k127_7065526_2 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
PYH1_k127_7065526_3 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006562 281.0
PYH1_k127_7065526_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
PYH1_k127_7065526_5 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002049 222.0
PYH1_k127_7065526_6 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000002913 156.0
PYH1_k127_7065526_7 nitric oxide dioxygenase activity - - - 0.000000000000005526 79.0
PYH1_k127_7065526_8 Permease MlaE K02066 - - 0.00000002525 55.0
PYH1_k127_7091184_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 368.0
PYH1_k127_7091184_1 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000008423 256.0
PYH1_k127_7091184_2 Met-10+ like-protein - - - 0.000000000000000000000000006894 117.0
PYH1_k127_7091184_3 toxin-antitoxin pair type II binding K19159 - - 0.00000000000000001655 86.0
PYH1_k127_7091184_4 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000002213 73.0
PYH1_k127_7091184_5 - - - - 0.00000006874 60.0
PYH1_k127_7103181_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 501.0
PYH1_k127_7103181_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
PYH1_k127_7103181_10 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000005626 127.0
PYH1_k127_7103181_11 Histidine kinase - - - 0.00000000000000000000000002675 115.0
PYH1_k127_7103181_12 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000008817 89.0
PYH1_k127_7103181_14 Thioredoxin-like - - - 0.0000000000007173 75.0
PYH1_k127_7103181_15 Belongs to the UPF0312 family - - - 0.0000004287 56.0
PYH1_k127_7103181_16 dUTPase K01520 - 3.6.1.23 0.0001369 51.0
PYH1_k127_7103181_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 355.0
PYH1_k127_7103181_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 301.0
PYH1_k127_7103181_4 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
PYH1_k127_7103181_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000003274 216.0
PYH1_k127_7103181_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000001298 196.0
PYH1_k127_7103181_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000008976 177.0
PYH1_k127_7103181_8 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000000000000000000001478 181.0
PYH1_k127_7103181_9 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000006208 129.0
PYH1_k127_7134251_0 Secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 446.0
PYH1_k127_7134251_1 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000001449 177.0
PYH1_k127_7134251_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000009393 79.0
PYH1_k127_7134251_4 - - - - 0.0006129 51.0
PYH1_k127_7137872_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.083e-246 777.0
PYH1_k127_7137872_1 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 373.0
PYH1_k127_7137872_10 Methyltransferase domain - - - 0.00000000000000000002356 100.0
PYH1_k127_7137872_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 329.0
PYH1_k127_7137872_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 300.0
PYH1_k127_7137872_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004336 265.0
PYH1_k127_7137872_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000002457 237.0
PYH1_k127_7137872_6 Sulfatase K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000002797 248.0
PYH1_k127_7137872_7 - - - - 0.0000000000000000000000000000000000000001008 174.0
PYH1_k127_7137872_8 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0000000000000000000000000000000000000002372 169.0
PYH1_k127_7137872_9 PFAM glycosyl transferase family 9 K02849 - - 0.000000000000000000000000006671 113.0
PYH1_k127_7151408_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 506.0
PYH1_k127_7151408_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 400.0
PYH1_k127_7151408_10 DeAcetylase - - - 0.00000000000000000000000000000000000000000000000000000404 209.0
PYH1_k127_7151408_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000002644 179.0
PYH1_k127_7151408_12 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000002542 130.0
PYH1_k127_7151408_13 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000021 137.0
PYH1_k127_7151408_14 Redoxin - - - 0.00000000000000000000000000004652 119.0
PYH1_k127_7151408_15 Thioredoxin - - - 0.00000000000000000002377 100.0
PYH1_k127_7151408_16 Domain of unknown function (DUF1844) - - - 0.0000000000000001533 84.0
PYH1_k127_7151408_17 peptidyl-tyrosine sulfation - - - 0.00000000002708 77.0
PYH1_k127_7151408_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000005734 63.0
PYH1_k127_7151408_2 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 376.0
PYH1_k127_7151408_3 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
PYH1_k127_7151408_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 292.0
PYH1_k127_7151408_5 SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000006208 274.0
PYH1_k127_7151408_6 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001764 257.0
PYH1_k127_7151408_7 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008636 254.0
PYH1_k127_7151408_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000002565 240.0
PYH1_k127_7151408_9 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
PYH1_k127_7171908_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 539.0
PYH1_k127_7171908_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 410.0
PYH1_k127_7171908_10 domain protein - - - 0.00000000000000000000000000000000000000000000000000000001695 212.0
PYH1_k127_7171908_11 HEAT repeat - - - 0.0000000000000000000000000000000000000001239 162.0
PYH1_k127_7171908_13 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000007923 153.0
PYH1_k127_7171908_14 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.00000000000000000000000006741 124.0
PYH1_k127_7171908_15 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000002013 85.0
PYH1_k127_7171908_16 ResB protein required for cytochrome c biosynthesis K07399 - - 0.00000000009041 74.0
PYH1_k127_7171908_17 peptidyl-tyrosine sulfation - - - 0.0001892 51.0
PYH1_k127_7171908_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 397.0
PYH1_k127_7171908_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 338.0
PYH1_k127_7171908_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 286.0
PYH1_k127_7171908_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001727 289.0
PYH1_k127_7171908_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002474 272.0
PYH1_k127_7171908_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001318 246.0
PYH1_k127_7171908_8 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000008134 237.0
PYH1_k127_7171908_9 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000002232 233.0
PYH1_k127_7315576_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 467.0
PYH1_k127_7315576_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 412.0
PYH1_k127_7315576_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 347.0
PYH1_k127_7315576_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 315.0
PYH1_k127_7315576_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 321.0
PYH1_k127_7315576_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 303.0
PYH1_k127_7315576_6 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000002102 178.0
PYH1_k127_7315576_7 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000004487 166.0
PYH1_k127_7315576_8 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000004938 115.0
PYH1_k127_7315576_9 cell redox homeostasis - - - 0.000000000000000000000296 109.0
PYH1_k127_7316008_0 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 288.0
PYH1_k127_7316008_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 255.0
PYH1_k127_7316008_2 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004457 232.0
PYH1_k127_7316008_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000001639 221.0
PYH1_k127_7316008_4 - - - - 0.000000000000000000000000006638 114.0
PYH1_k127_7316008_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000002917 109.0
PYH1_k127_7316008_6 ABC-type uncharacterized transport system - - - 0.00005188 48.0
PYH1_k127_7549629_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.369e-272 863.0
PYH1_k127_7549629_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.086e-245 768.0
PYH1_k127_7549629_10 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 303.0
PYH1_k127_7549629_11 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 292.0
PYH1_k127_7549629_12 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002628 269.0
PYH1_k127_7549629_13 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000001235 240.0
PYH1_k127_7549629_14 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000112 213.0
PYH1_k127_7549629_15 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000002064 184.0
PYH1_k127_7549629_16 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000001531 178.0
PYH1_k127_7549629_17 - - - - 0.00000000000000000000000000000000000000000000007332 173.0
PYH1_k127_7549629_18 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000001042 174.0
PYH1_k127_7549629_19 Nitroreductase family - - - 0.000000000000000000000000000000000000000000002366 170.0
PYH1_k127_7549629_2 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 7.638e-236 740.0
PYH1_k127_7549629_20 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000009215 153.0
PYH1_k127_7549629_21 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000005893 151.0
PYH1_k127_7549629_22 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000007421 145.0
PYH1_k127_7549629_23 Biotin-requiring enzyme - - - 0.000000000000000000000000004215 117.0
PYH1_k127_7549629_24 COG COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00180 - 1.2.7.8 0.00000000000000000000001296 109.0
PYH1_k127_7549629_25 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC K09667 - 2.4.1.255 0.000000000000000000008184 101.0
PYH1_k127_7549629_3 Biotin carboxylase C-terminal domain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 548.0
PYH1_k127_7549629_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 549.0
PYH1_k127_7549629_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 381.0
PYH1_k127_7549629_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
PYH1_k127_7549629_7 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 361.0
PYH1_k127_7549629_8 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 366.0
PYH1_k127_7549629_9 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 360.0
PYH1_k127_7549902_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 445.0
PYH1_k127_7549902_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008599 283.0
PYH1_k127_7549902_2 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000000000005366 228.0
PYH1_k127_7549902_3 PFAM VanZ family protein - - - 0.000004208 59.0
PYH1_k127_7577390_0 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 567.0
PYH1_k127_7577390_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 552.0
PYH1_k127_7577390_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
PYH1_k127_7577390_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000004543 168.0
PYH1_k127_7577390_4 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000209 149.0
PYH1_k127_7577390_5 Tetratricopeptide repeat - - - 0.00000000001448 78.0
PYH1_k127_7577390_6 Displays ATPase and GTPase activities K06958 - - 0.000002515 51.0
PYH1_k127_7644221_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.775e-203 638.0
PYH1_k127_7644221_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 531.0
PYH1_k127_7644221_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
PYH1_k127_7644221_3 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000002217 127.0
PYH1_k127_7644221_4 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000001609 116.0
PYH1_k127_7644221_5 system, mannose fructose sorbose family IID component K02795,K02796,K10986 - - 0.0000000000000000000005369 109.0
PYH1_k127_7644221_6 PTS HPr component phosphorylation site K11189 - - 0.0000000000003163 83.0
PYH1_k127_7644221_7 PTS system sorbose-specific iic component K02795 - - 0.000002024 59.0
PYH1_k127_7648850_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.106e-232 735.0
PYH1_k127_7648850_1 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 4.861e-229 715.0
PYH1_k127_7648850_10 potassium uptake protein TrkH K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 364.0
PYH1_k127_7648850_11 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 258.0
PYH1_k127_7648850_12 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000332 258.0
PYH1_k127_7648850_13 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000007702 218.0
PYH1_k127_7648850_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
PYH1_k127_7648850_15 succinate dehydrogenase K00241 - - 0.000000000000000000001971 97.0
PYH1_k127_7648850_16 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000003222 91.0
PYH1_k127_7648850_17 GIY-YIG catalytic domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000002042 89.0
PYH1_k127_7648850_18 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000001873 69.0
PYH1_k127_7648850_19 His Kinase A (phosphoacceptor) domain - - - 0.0000001786 64.0
PYH1_k127_7648850_2 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 7.895e-201 640.0
PYH1_k127_7648850_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 495.0
PYH1_k127_7648850_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 472.0
PYH1_k127_7648850_5 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 471.0
PYH1_k127_7648850_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 456.0
PYH1_k127_7648850_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 410.0
PYH1_k127_7648850_8 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 394.0
PYH1_k127_7648850_9 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 362.0
PYH1_k127_7675048_0 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 472.0
PYH1_k127_7675048_1 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 454.0
PYH1_k127_7675048_10 Pfam:N_methyl_2 - - - 0.0000001011 67.0
PYH1_k127_7675048_11 Prokaryotic N-terminal methylation motif - - - 0.0000003045 59.0
PYH1_k127_7675048_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 348.0
PYH1_k127_7675048_3 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 325.0
PYH1_k127_7675048_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 288.0
PYH1_k127_7675048_5 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000001623 256.0
PYH1_k127_7675048_6 PFAM helix-turn-helix domain protein - - - 0.0000000000000001643 81.0
PYH1_k127_7675048_7 Pilus assembly protein PilX - - - 0.000000000000001111 91.0
PYH1_k127_7675048_8 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.0000000005743 66.0
PYH1_k127_7675048_9 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000285 66.0
PYH1_k127_7687251_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 350.0
PYH1_k127_7687251_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
PYH1_k127_7687251_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000007799 153.0
PYH1_k127_7687251_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000009421 141.0
PYH1_k127_7687251_4 PFAM Tetratricopeptide repeat - - - 0.0000000000000001794 83.0
PYH1_k127_7720016_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.631e-234 740.0
PYH1_k127_7720016_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 390.0
PYH1_k127_7720016_10 PFAM peptidase - - - 0.0000000000000000000000000005137 123.0
PYH1_k127_7720016_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000002627 67.0
PYH1_k127_7720016_2 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 320.0
PYH1_k127_7720016_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 302.0
PYH1_k127_7720016_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 298.0
PYH1_k127_7720016_5 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000119 316.0
PYH1_k127_7720016_6 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004714 280.0
PYH1_k127_7720016_7 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001297 246.0
PYH1_k127_7720016_8 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002707 258.0
PYH1_k127_7720016_9 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000002183 203.0
PYH1_k127_7735270_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.977e-195 619.0
PYH1_k127_7735270_1 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 556.0
PYH1_k127_7735270_10 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000003976 211.0
PYH1_k127_7735270_11 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000142 196.0
PYH1_k127_7735270_12 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000001953 171.0
PYH1_k127_7735270_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000001572 167.0
PYH1_k127_7735270_14 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000002517 168.0
PYH1_k127_7735270_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000009853 161.0
PYH1_k127_7735270_16 CcmB protein K02194 - - 0.0000000000000000000000000000000000000002249 159.0
PYH1_k127_7735270_17 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000001983 143.0
PYH1_k127_7735270_18 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000003705 141.0
PYH1_k127_7735270_19 lyase activity - - - 0.0000000000000000000000000000001085 143.0
PYH1_k127_7735270_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 513.0
PYH1_k127_7735270_20 phosphorelay signal transduction system - - - 0.0000000000000000000000000008496 119.0
PYH1_k127_7735270_21 Tetratricopeptide repeat - - - 0.00000000000000000000001299 113.0
PYH1_k127_7735270_22 Helix-turn-helix domain - - - 0.0000000000000000000002785 105.0
PYH1_k127_7735270_23 PASTA K12132 - 2.7.11.1 0.000000000000000000005704 108.0
PYH1_k127_7735270_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000006785 94.0
PYH1_k127_7735270_25 YacP-like NYN domain K06962 - - 0.0000000005807 66.0
PYH1_k127_7735270_26 Cell envelope-related transcriptional attenuator domain - - - 0.0009433 51.0
PYH1_k127_7735270_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
PYH1_k127_7735270_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
PYH1_k127_7735270_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000977 280.0
PYH1_k127_7735270_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003651 280.0
PYH1_k127_7735270_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000007871 255.0
PYH1_k127_7735270_8 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000008081 244.0
PYH1_k127_7735270_9 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000008167 207.0
PYH1_k127_7849141_0 Heat shock 70 kDa protein K04043 - - 5.927e-265 829.0
PYH1_k127_7849141_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 297.0
PYH1_k127_7849141_2 YceI-like domain - - - 0.00000000000000000000000000000000000000008597 156.0
PYH1_k127_7849141_3 peroxiredoxin activity - - - 0.000000000000000000000000004715 126.0
PYH1_k127_7849141_4 Thioredoxin-like - - - 0.000000000000000001563 98.0
PYH1_k127_7849141_5 Thiamine-binding protein - - - 0.00000000000002565 77.0
PYH1_k127_7849141_6 - - - - 0.00000007052 65.0
PYH1_k127_7849141_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00009891 54.0
PYH1_k127_7852678_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.22e-230 751.0
PYH1_k127_7852678_1 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 1.208e-205 646.0
PYH1_k127_7852678_2 PFAM ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 601.0
PYH1_k127_7852678_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
PYH1_k127_7852678_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 275.0
PYH1_k127_7854758_0 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.0 1235.0
PYH1_k127_7854758_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.889e-199 636.0
PYH1_k127_7854758_2 cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 348.0
PYH1_k127_7854758_3 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 358.0
PYH1_k127_7854758_5 - - - - 0.000000000000000000000000000000001237 130.0
PYH1_k127_7854758_6 - - - - 0.000000000000000000001571 102.0
PYH1_k127_7854758_7 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000007127 98.0
PYH1_k127_7854758_8 Diguanylate cyclase - - - 0.0000000000000112 86.0
PYH1_k127_794638_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 537.0
PYH1_k127_794638_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 316.0
PYH1_k127_794638_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005072 290.0
PYH1_k127_794638_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 272.0
PYH1_k127_794638_4 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000005106 161.0
PYH1_k127_794638_5 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000006686 133.0
PYH1_k127_794638_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000004912 100.0
PYH1_k127_794638_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000021 93.0
PYH1_k127_794638_8 Predicted membrane protein (DUF2232) - - - 0.0000000002432 72.0
PYH1_k127_7963272_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 437.0
PYH1_k127_7963272_1 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
PYH1_k127_7963272_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000002083 173.0
PYH1_k127_7963272_3 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000003042 153.0
PYH1_k127_7963272_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000049 66.0
PYH1_k127_7963272_5 Displays ATPase and GTPase activities K06958 - - 0.000002064 51.0
PYH1_k127_8052284_0 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 434.0
PYH1_k127_8052284_1 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 360.0
PYH1_k127_8052284_10 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000001486 231.0
PYH1_k127_8052284_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000146 215.0
PYH1_k127_8052284_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
PYH1_k127_8052284_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000006681 195.0
PYH1_k127_8052284_14 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K03273,K15669 - 2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000001074 181.0
PYH1_k127_8052284_15 Methyltransferase domain - - - 0.000000000000000000000000000000001561 139.0
PYH1_k127_8052284_16 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000005247 128.0
PYH1_k127_8052284_17 Polysaccharide biosynthesis C-terminal domain K03328 - - 0.000000000000000000000000000001482 139.0
PYH1_k127_8052284_18 Glycosyl transferases group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.00000000000000000002261 104.0
PYH1_k127_8052284_19 methyltransferase K16215 - 2.1.1.243 0.000000000000000004973 93.0
PYH1_k127_8052284_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 356.0
PYH1_k127_8052284_20 Methyltransferase - - - 0.00000000000000001829 91.0
PYH1_k127_8052284_21 - - - - 0.000001918 60.0
PYH1_k127_8052284_22 Tetratricopeptide TPR_2 repeat protein - - - 0.00007549 48.0
PYH1_k127_8052284_23 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0001573 54.0
PYH1_k127_8052284_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
PYH1_k127_8052284_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 308.0
PYH1_k127_8052284_5 dTDP-4-dehydrorhamnose reductase activity K00067,K01790,K19997 - 1.1.1.133,5.1.3.13,5.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000002368 269.0
PYH1_k127_8052284_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005004 252.0
PYH1_k127_8052284_7 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000001811 247.0
PYH1_k127_8052284_8 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
PYH1_k127_8052284_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000001324 230.0
PYH1_k127_8162999_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 576.0
PYH1_k127_8162999_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 469.0
PYH1_k127_8162999_2 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 447.0
PYH1_k127_8162999_3 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000009824 270.0
PYH1_k127_8162999_4 - - - - 0.00000000426 67.0
PYH1_k127_8225351_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 486.0
PYH1_k127_8225351_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 430.0
PYH1_k127_8225351_10 cellulose binding K07279 - - 0.0005655 50.0
PYH1_k127_8225351_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 374.0
PYH1_k127_8225351_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 339.0
PYH1_k127_8225351_4 4Fe-4S binding domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002778 259.0
PYH1_k127_8225351_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
PYH1_k127_8225351_6 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000009053 219.0
PYH1_k127_8225351_7 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000002681 156.0
PYH1_k127_8225351_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000005197 113.0
PYH1_k127_836414_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 437.0
PYH1_k127_836414_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000004609 265.0
PYH1_k127_836414_2 Bacterial type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000001438 153.0
PYH1_k127_836414_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000007998 128.0
PYH1_k127_871375_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1156.0
PYH1_k127_871375_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 383.0
PYH1_k127_871375_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000002097 230.0
PYH1_k127_871375_11 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000003951 183.0
PYH1_k127_871375_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 376.0
PYH1_k127_871375_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 332.0
PYH1_k127_871375_4 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 333.0
PYH1_k127_871375_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 323.0
PYH1_k127_871375_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 294.0
PYH1_k127_871375_7 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002544 289.0
PYH1_k127_871375_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001763 267.0
PYH1_k127_871375_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
PYH1_k127_93267_0 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 618.0
PYH1_k127_93267_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 580.0
PYH1_k127_93267_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001741 168.0
PYH1_k127_93267_11 Flagellar hook protein flgE - - - 0.000000000000000000000000000000000000000004277 179.0
PYH1_k127_93267_12 Smr domain - - - 0.00000000000000000000000000000002652 132.0
PYH1_k127_93267_13 Putative prokaryotic signal transducing protein - - - 0.0000000000001549 73.0
PYH1_k127_93267_2 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 352.0
PYH1_k127_93267_3 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 314.0
PYH1_k127_93267_4 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002514 293.0
PYH1_k127_93267_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007875 278.0
PYH1_k127_93267_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
PYH1_k127_93267_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000003071 224.0
PYH1_k127_93267_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.00000000000000000000000000000000000000000000000000000006239 197.0
PYH1_k127_93267_9 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.000000000000000000000000000000000000000000009079 187.0
PYH1_k127_934197_0 GAF domain - - - 0.000000000000000000000000000000000000000004719 175.0
PYH1_k127_94575_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 314.0
PYH1_k127_94575_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007828 258.0
PYH1_k127_94575_2 Solute carrier family 16, member 13 K08189 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0012505,GO:0015075,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.0000000000004379 81.0
PYH1_k127_94575_3 membrane protein, required for N-linked glycosylation K07151 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0045229,GO:0045232,GO:0071840 2.4.99.18 0.00000000001291 73.0
PYH1_k127_985737_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.038e-223 705.0
PYH1_k127_985737_1 Uncharacterized conserved protein (DUF2075) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 390.0
PYH1_k127_985737_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000167 179.0
PYH1_k127_985737_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000003884 136.0
PYH1_k127_985737_4 Plasmid stability protein K21495 - - 0.00000000000004535 74.0
PYH1_k127_985737_6 - - - - 0.00007729 48.0
PYH1_k127_98965_0 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 406.0
PYH1_k127_98965_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 389.0
PYH1_k127_98965_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 336.0
PYH1_k127_98965_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 323.0
PYH1_k127_98965_4 PFAM CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000001995 237.0
PYH1_k127_98965_5 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000007331 184.0
PYH1_k127_98965_6 Uncharacterized protein family UPF0054 - - - 0.00000000000000000009967 95.0
PYH1_k127_98965_7 Tetratricopeptide repeat - - - 0.0007856 46.0