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Overview

ID MAG03142
Name PYH1_bin.32
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 72.3
Contamination (%) 3.12
GC content (%) 69.0
N50 (bp) 4,747
Genome size (bp) 2,121,256

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2244

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1047918_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 388.0
PYH1_k127_1047918_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000007124 182.0
PYH1_k127_1047918_2 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000001896 158.0
PYH1_k127_1047918_3 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000177 128.0
PYH1_k127_1047918_4 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000211 112.0
PYH1_k127_1047918_5 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000003818 89.0
PYH1_k127_1059026_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 347.0
PYH1_k127_1059026_1 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
PYH1_k127_1059026_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000002931 90.0
PYH1_k127_1059026_3 17 kDa surface antigen K06077 - - 0.000000000004152 66.0
PYH1_k127_1084396_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1254.0
PYH1_k127_1084396_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.9e-221 690.0
PYH1_k127_1084396_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 552.0
PYH1_k127_1084396_3 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 456.0
PYH1_k127_1084396_4 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 416.0
PYH1_k127_1084396_5 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 365.0
PYH1_k127_1084396_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 353.0
PYH1_k127_1084396_7 - - - - 0.0005039 52.0
PYH1_k127_1085660_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2463.0
PYH1_k127_1085660_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 514.0
PYH1_k127_1085660_2 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003745 274.0
PYH1_k127_1086948_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 7.706e-270 834.0
PYH1_k127_1086948_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.223e-216 679.0
PYH1_k127_1086948_2 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
PYH1_k127_1086948_3 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000004776 153.0
PYH1_k127_1086948_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000004445 83.0
PYH1_k127_1099646_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 541.0
PYH1_k127_1099646_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000003295 261.0
PYH1_k127_1099646_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000001677 228.0
PYH1_k127_1127972_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 507.0
PYH1_k127_1127972_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 301.0
PYH1_k127_1127972_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000002301 174.0
PYH1_k127_1138645_0 PFAM ABC-1 domain protein K03688 - - 2.384e-248 777.0
PYH1_k127_1138645_1 - - - - 0.000000000000000000000000000000000000000000000000000005079 197.0
PYH1_k127_1138645_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000002222 184.0
PYH1_k127_1138645_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0002478 46.0
PYH1_k127_1140888_0 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 464.0
PYH1_k127_1140888_1 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 312.0
PYH1_k127_1140888_2 FMN_bind K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000005272 249.0
PYH1_k127_1140888_3 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000001452 209.0
PYH1_k127_1159186_0 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 485.0
PYH1_k127_1159186_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000003293 193.0
PYH1_k127_1159186_2 Lipocalin-like domain K03098 - - 0.00000000000000000002074 91.0
PYH1_k127_1217997_0 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000709 239.0
PYH1_k127_1223517_0 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 502.0
PYH1_k127_1223517_1 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 367.0
PYH1_k127_1223517_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002674 262.0
PYH1_k127_1223517_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000004102 220.0
PYH1_k127_1223517_4 - - - - 0.00000000000000000000000000000000000000000000003354 178.0
PYH1_k127_1223517_6 - - - - 0.0000002214 57.0
PYH1_k127_1223517_7 Peptidase family M48 - - - 0.0001209 45.0
PYH1_k127_1232908_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1061.0
PYH1_k127_1232908_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.326e-232 726.0
PYH1_k127_1232908_2 Transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
PYH1_k127_1232908_3 Haem-degrading - - - 0.0000000000000000000000000000000000008024 159.0
PYH1_k127_1232908_4 - - - - 0.000000000000000000001682 96.0
PYH1_k127_1232908_5 - - - - 0.000000000000000007538 86.0
PYH1_k127_1261941_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1643.0
PYH1_k127_126851_0 argininosuccinate lyase K01755 - 4.3.2.1 6.106e-211 663.0
PYH1_k127_126851_1 Histidine kinase K08082 - 2.7.13.3 0.00000000007568 68.0
PYH1_k127_1286885_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.937e-265 822.0
PYH1_k127_1286885_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 409.0
PYH1_k127_1286885_2 - - - - 0.0000000000001209 78.0
PYH1_k127_1286885_3 Major facilitator Superfamily - - - 0.0000000006316 66.0
PYH1_k127_1286885_4 Domain of unknown function (DUF4124) - - - 0.00009136 53.0
PYH1_k127_1294548_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.485e-227 718.0
PYH1_k127_1294548_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 503.0
PYH1_k127_1294548_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 412.0
PYH1_k127_1294548_3 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 392.0
PYH1_k127_1294548_4 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000002354 212.0
PYH1_k127_1294548_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000003325 191.0
PYH1_k127_1294548_6 protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000001447 169.0
PYH1_k127_1311005_0 Belongs to the CarB family K01955 - 6.3.5.5 3.71e-299 925.0
PYH1_k127_1311005_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008589 260.0
PYH1_k127_1311005_2 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000008755 123.0
PYH1_k127_1313272_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.017e-210 663.0
PYH1_k127_1313272_1 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000004591 228.0
PYH1_k127_1313272_2 - - - - 0.0000000002233 61.0
PYH1_k127_1313272_3 Staphylococcal nuclease homologues - - - 0.0000000004525 63.0
PYH1_k127_1325082_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1212.0
PYH1_k127_1325082_1 photosynthesis - - - 0.00000000000000000000000000000000000000000000000001506 184.0
PYH1_k127_1326433_0 TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA K03694 - - 0.0 1179.0
PYH1_k127_1326433_1 sulfide dehydrogenase K05301 - 1.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 514.0
PYH1_k127_1326433_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 329.0
PYH1_k127_1326433_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 328.0
PYH1_k127_1326433_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
PYH1_k127_1326433_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000005339 162.0
PYH1_k127_1326433_6 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000005352 149.0
PYH1_k127_1326433_7 cytochrome - - - 0.0000000000000002858 83.0
PYH1_k127_1331408_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.887e-250 779.0
PYH1_k127_1331408_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 560.0
PYH1_k127_1331408_2 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 510.0
PYH1_k127_1331408_3 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 385.0
PYH1_k127_1331408_4 Protein of unknown function (DUF465) - - - 0.0000000000000005323 81.0
PYH1_k127_133469_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1005.0
PYH1_k127_133469_1 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000002917 198.0
PYH1_k127_133469_2 Pfam Glutaredoxin - - - 0.0000000000000000000000000000007446 141.0
PYH1_k127_1338760_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1189.0
PYH1_k127_1338760_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 419.0
PYH1_k127_1338760_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 367.0
PYH1_k127_1338760_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000001087 132.0
PYH1_k127_1338760_4 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.00000000000000000000000000000247 127.0
PYH1_k127_1353056_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 561.0
PYH1_k127_1353056_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005787 263.0
PYH1_k127_1353056_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000009142 153.0
PYH1_k127_1365077_0 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
PYH1_k127_1365077_1 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000172 221.0
PYH1_k127_1365077_2 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000009482 102.0
PYH1_k127_1383888_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1337.0
PYH1_k127_1383888_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 443.0
PYH1_k127_1396597_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 1.539e-271 849.0
PYH1_k127_1396597_1 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 306.0
PYH1_k127_1415945_0 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
PYH1_k127_1415945_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 350.0
PYH1_k127_1415945_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000009547 198.0
PYH1_k127_1415945_3 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000007399 132.0
PYH1_k127_1431380_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1151.0
PYH1_k127_1431380_1 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 275.0
PYH1_k127_1432593_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 595.0
PYH1_k127_1432593_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 462.0
PYH1_k127_1432593_2 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 420.0
PYH1_k127_1432593_3 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 317.0
PYH1_k127_1432593_4 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000003412 205.0
PYH1_k127_1438572_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1120.0
PYH1_k127_1438572_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 610.0
PYH1_k127_1438572_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 561.0
PYH1_k127_1438572_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 365.0
PYH1_k127_1438572_4 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000315 128.0
PYH1_k127_1469874_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 2.044e-266 825.0
PYH1_k127_1469874_1 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
PYH1_k127_1469874_2 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000398 256.0
PYH1_k127_1469874_3 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000007576 234.0
PYH1_k127_1469874_4 maturation - - - 0.0000000000000000000000000000000000000000000009241 171.0
PYH1_k127_1469874_5 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000947 165.0
PYH1_k127_1469874_6 Protein of unknown function (DUF504) - - - 0.00000000000000000003838 101.0
PYH1_k127_1470036_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 385.0
PYH1_k127_1470036_1 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 307.0
PYH1_k127_1470036_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000003228 234.0
PYH1_k127_1470036_3 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000002402 155.0
PYH1_k127_1482449_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 584.0
PYH1_k127_1482449_1 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
PYH1_k127_1482449_2 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000001592 154.0
PYH1_k127_1482449_3 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000004818 156.0
PYH1_k127_1482449_4 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000001015 137.0
PYH1_k127_1482449_5 Cytochrome C assembly protein - - - 0.00000000000001805 86.0
PYH1_k127_1501207_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 595.0
PYH1_k127_1501207_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000005419 148.0
PYH1_k127_1501207_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000001376 118.0
PYH1_k127_1503335_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
PYH1_k127_1503335_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 372.0
PYH1_k127_1503335_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 327.0
PYH1_k127_1503335_3 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
PYH1_k127_1503335_4 Rubredoxin - - - 0.0000000000000000000000004336 118.0
PYH1_k127_1503335_5 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000002274 59.0
PYH1_k127_1503335_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000003902 57.0
PYH1_k127_1509037_0 4Fe-4S double cluster binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 338.0
PYH1_k127_1509037_1 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000002785 129.0
PYH1_k127_1509037_2 SdpI/YhfL protein family - - - 0.000000000000000001734 97.0
PYH1_k127_1509037_3 - - - - 0.0008296 49.0
PYH1_k127_1511660_0 Bacterial regulatory protein, Fis family K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 461.0
PYH1_k127_1511660_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.0000000000000000000000000000000000000000000000005909 177.0
PYH1_k127_157240_0 alpha beta hydrolase fold K03821 - - 5.442e-240 753.0
PYH1_k127_157240_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 350.0
PYH1_k127_157240_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 321.0
PYH1_k127_157240_3 Putative regulatory protein - - - 0.00000000000000000000000000001192 121.0
PYH1_k127_1587942_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.236e-270 841.0
PYH1_k127_1587942_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
PYH1_k127_1587942_2 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000009154 69.0
PYH1_k127_1592339_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 519.0
PYH1_k127_1592339_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 288.0
PYH1_k127_1592339_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000001643 246.0
PYH1_k127_1620943_0 Glucose / Sorbosone dehydrogenase - - - 2.371e-234 730.0
PYH1_k127_1620943_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.112e-215 684.0
PYH1_k127_1620943_2 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 372.0
PYH1_k127_1620943_3 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 264.0
PYH1_k127_1620943_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
PYH1_k127_1620943_5 Cytochrome c - - - 0.00000000000000000000008307 109.0
PYH1_k127_1620943_6 Metallo-beta-lactamase superfamily - - - 0.000000000000003992 76.0
PYH1_k127_1654745_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.5e-323 996.0
PYH1_k127_1654745_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000005914 166.0
PYH1_k127_1667012_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.058e-227 715.0
PYH1_k127_1674377_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 498.0
PYH1_k127_1674377_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
PYH1_k127_1674377_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000262 261.0
PYH1_k127_1691209_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 474.0
PYH1_k127_1691209_1 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 315.0
PYH1_k127_1691339_0 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 520.0
PYH1_k127_1691339_1 glycolate oxidase subunit GlcD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 383.0
PYH1_k127_1721695_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1378.0
PYH1_k127_1721695_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 426.0
PYH1_k127_1721695_2 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
PYH1_k127_1721695_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000004267 240.0
PYH1_k127_1721695_4 - - - - 0.00000000000000000003934 94.0
PYH1_k127_1723929_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 544.0
PYH1_k127_1723929_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
PYH1_k127_1723929_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
PYH1_k127_1723929_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000002158 135.0
PYH1_k127_1724960_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1129.0
PYH1_k127_1724960_1 Insecticidal toxin complex protein TcaC - - - 0.00000000000000000000000000000000000000003395 168.0
PYH1_k127_1726404_0 PFAM multicopper oxidase type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 576.0
PYH1_k127_1726404_1 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007067 234.0
PYH1_k127_1748115_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 589.0
PYH1_k127_1748115_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
PYH1_k127_1764588_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 304.0
PYH1_k127_1764588_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000001815 179.0
PYH1_k127_1764588_2 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000001799 108.0
PYH1_k127_1764588_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00003745 46.0
PYH1_k127_1768123_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1258.0
PYH1_k127_1768123_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 6.309e-209 670.0
PYH1_k127_1768123_2 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 418.0
PYH1_k127_1768123_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
PYH1_k127_1768123_4 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 318.0
PYH1_k127_1768123_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 295.0
PYH1_k127_1768123_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
PYH1_k127_1768123_7 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000182 139.0
PYH1_k127_1782588_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 401.0
PYH1_k127_1782588_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002563 272.0
PYH1_k127_1782588_2 Universal stress protein - - - 0.00000000000000000000000000000000001151 144.0
PYH1_k127_1782588_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000004171 114.0
PYH1_k127_1789420_0 polyphosphate kinase - - - 3.911e-230 722.0
PYH1_k127_1789420_1 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000004968 176.0
PYH1_k127_1790916_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2227.0
PYH1_k127_1790916_1 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 399.0
PYH1_k127_1790916_2 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000002718 197.0
PYH1_k127_1790916_3 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000002936 121.0
PYH1_k127_1797835_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 537.0
PYH1_k127_1797835_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 353.0
PYH1_k127_1797835_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000002918 163.0
PYH1_k127_1797835_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000001734 89.0
PYH1_k127_1797835_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000009228 80.0
PYH1_k127_1800320_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 561.0
PYH1_k127_1809229_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1363.0
PYH1_k127_1809229_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 4.086e-220 689.0
PYH1_k127_1809229_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 556.0
PYH1_k127_1809229_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 463.0
PYH1_k127_1809229_4 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 372.0
PYH1_k127_1809229_5 ArgJ family K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000003245 143.0
PYH1_k127_1809229_6 Protein conserved in bacteria - - - 0.0000000000000912 84.0
PYH1_k127_1816164_0 4Fe-4S dicluster domain - - - 1.181e-232 745.0
PYH1_k127_1816164_1 Protein of unknown function (DUF3306) - - - 0.00000000000000000000000244 107.0
PYH1_k127_1847841_0 Cytochrome b(N-terminal)/b6/petB - - - 1.96e-253 797.0
PYH1_k127_1847841_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 291.0
PYH1_k127_1847841_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 286.0
PYH1_k127_1847841_3 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005494 262.0
PYH1_k127_1847841_4 - - - - 0.0000000000000000000000000000000000000003371 155.0
PYH1_k127_1851587_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 4.365e-199 650.0
PYH1_k127_1851587_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
PYH1_k127_1851587_2 - - - - 0.0000000000000000000001172 104.0
PYH1_k127_1851587_3 Glycine-zipper domain - - - 0.0000000000000000000002511 99.0
PYH1_k127_1857078_0 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 457.0
PYH1_k127_1857078_1 PFAM LemA family K03744 - - 0.00000000000000000000000000009549 117.0
PYH1_k127_1862417_0 ribonuclease, Rne Rng family K08301 - - 6.955e-233 739.0
PYH1_k127_1862417_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000575 271.0
PYH1_k127_1862417_2 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
PYH1_k127_1862417_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000002904 111.0
PYH1_k127_1862417_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000005796 112.0
PYH1_k127_1862417_5 DUF167 K09131 - - 0.00000000000000000000000006413 110.0
PYH1_k127_1868041_0 TonB-dependent receptor K02014 - - 1.041e-216 702.0
PYH1_k127_1868041_1 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 397.0
PYH1_k127_1868041_2 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 385.0
PYH1_k127_1868041_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005394 261.0
PYH1_k127_1868041_4 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
PYH1_k127_1868041_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000006677 199.0
PYH1_k127_1868041_6 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
PYH1_k127_1877732_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
PYH1_k127_1877732_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 290.0
PYH1_k127_1877732_2 - - - - 0.0001283 54.0
PYH1_k127_1892944_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 559.0
PYH1_k127_1892944_1 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 462.0
PYH1_k127_1892944_2 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 467.0
PYH1_k127_1892944_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 446.0
PYH1_k127_1892944_4 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 397.0
PYH1_k127_1990015_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 505.0
PYH1_k127_1990015_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 362.0
PYH1_k127_1990015_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001404 247.0
PYH1_k127_1990015_3 - - - - 0.00000000000003012 79.0
PYH1_k127_1994506_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 8.416e-203 656.0
PYH1_k127_1994506_1 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003087 254.0
PYH1_k127_2014714_0 protein synthesis factor, GTP-binding K06207 - - 1.229e-306 948.0
PYH1_k127_2019894_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 543.0
PYH1_k127_2019894_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000006549 78.0
PYH1_k127_2027794_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.128e-269 837.0
PYH1_k127_2027794_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 319.0
PYH1_k127_2066491_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 454.0
PYH1_k127_2066491_1 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 386.0
PYH1_k127_2066491_2 DsrC like protein K11179 - - 0.000000000000000000000000000000739 126.0
PYH1_k127_2066491_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000001409 65.0
PYH1_k127_210588_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 517.0
PYH1_k127_210588_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 495.0
PYH1_k127_210588_2 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 445.0
PYH1_k127_210588_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
PYH1_k127_210588_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000001212 280.0
PYH1_k127_210588_5 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000000000001326 125.0
PYH1_k127_210588_6 Thioredoxin-like - - - 0.00000000000000000000000000007437 124.0
PYH1_k127_2120699_0 Multicopper oxidase K22349 - 1.16.3.3 8.054e-226 717.0
PYH1_k127_2126309_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 447.0
PYH1_k127_2126309_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
PYH1_k127_2126309_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 356.0
PYH1_k127_2126309_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 341.0
PYH1_k127_2126309_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 318.0
PYH1_k127_2126309_5 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000002484 111.0
PYH1_k127_2138801_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1260.0
PYH1_k127_2138801_1 PFAM Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 542.0
PYH1_k127_2138801_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
PYH1_k127_2138801_3 Protein of unknown function (DUF2934) - - - 0.0000002356 53.0
PYH1_k127_2176757_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000003099 246.0
PYH1_k127_2176757_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000004684 195.0
PYH1_k127_217796_0 FeS assembly protein SufB K09014 - - 3.09e-276 855.0
PYH1_k127_217796_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 589.0
PYH1_k127_217796_10 NnrU protein - - - 0.0000006047 52.0
PYH1_k127_217796_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 456.0
PYH1_k127_217796_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
PYH1_k127_217796_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
PYH1_k127_217796_5 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
PYH1_k127_217796_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002666 172.0
PYH1_k127_217796_7 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000000000000000000000000000000000000006405 154.0
PYH1_k127_217796_8 PaaD-like protein - - - 0.00000000000000000000000000000000000002592 146.0
PYH1_k127_217796_9 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000003005 122.0
PYH1_k127_2181110_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 378.0
PYH1_k127_2181110_1 Methyl-transferase K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 355.0
PYH1_k127_2181110_2 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000005582 196.0
PYH1_k127_2190401_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003042 267.0
PYH1_k127_2190401_1 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000462 207.0
PYH1_k127_2190401_2 ribonuclease II K01147 - 3.1.13.1 0.0000000000000000000000000000000000000002253 152.0
PYH1_k127_2207201_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 2.427e-237 744.0
PYH1_k127_2223875_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.427e-234 747.0
PYH1_k127_2223875_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 531.0
PYH1_k127_2223875_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000004274 209.0
PYH1_k127_2223875_3 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000001206 203.0
PYH1_k127_2223875_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000001162 192.0
PYH1_k127_2223875_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000006969 128.0
PYH1_k127_2223875_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000007991 58.0
PYH1_k127_2245109_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0 1022.0
PYH1_k127_2245109_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 251.0
PYH1_k127_2245109_2 - - - - 0.000000000000000000000000002529 119.0
PYH1_k127_2245109_3 YMGG-like Gly-zipper - - - 0.0000000000000000004187 88.0
PYH1_k127_2249507_0 extracellular solute-binding protein - - - 0.0 1025.0
PYH1_k127_2249507_1 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 598.0
PYH1_k127_2249507_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 520.0
PYH1_k127_2249507_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 429.0
PYH1_k127_2249507_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000002732 197.0
PYH1_k127_2249507_5 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000002815 125.0
PYH1_k127_2249507_6 - - - - 0.00000000004237 65.0
PYH1_k127_225984_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 537.0
PYH1_k127_225984_1 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008768 246.0
PYH1_k127_2318691_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 380.0
PYH1_k127_2318691_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 352.0
PYH1_k127_2318691_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000002922 72.0
PYH1_k127_2318831_0 GMP synthase C terminal domain K01951 - 6.3.5.2 1.485e-299 923.0
PYH1_k127_2318831_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.618e-248 773.0
PYH1_k127_2318831_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000007659 145.0
PYH1_k127_2318831_3 Domain of unknown function (DUF4124) - - - 0.0000000000000007687 85.0
PYH1_k127_2342703_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 6.065e-195 612.0
PYH1_k127_2342703_1 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 377.0
PYH1_k127_2342703_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000008065 237.0
PYH1_k127_2342703_3 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000244 205.0
PYH1_k127_2342703_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000001761 116.0
PYH1_k127_2342703_5 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000005159 70.0
PYH1_k127_2366770_0 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003985 265.0
PYH1_k127_2366770_1 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000004889 195.0
PYH1_k127_2366770_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000006508 130.0
PYH1_k127_2366770_3 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000001138 110.0
PYH1_k127_2416118_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 439.0
PYH1_k127_2416118_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000003035 148.0
PYH1_k127_2443129_0 nitrous oxide reductase K00376 - 1.7.2.4 0.0 1049.0
PYH1_k127_2443129_1 4Fe-4S binding domain - - - 0.0 1040.0
PYH1_k127_2443129_2 Periplasmic copper-binding protein (NosD) K07218 - - 2.89e-211 670.0
PYH1_k127_2443129_3 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 427.0
PYH1_k127_2443129_4 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 404.0
PYH1_k127_2443129_5 NosL K19342 - - 0.000000000000000000000000000000000000000000000000000000000000002193 234.0
PYH1_k127_2443129_6 domain, Protein - - - 0.0000000000000000000000000000000000000000000001834 173.0
PYH1_k127_2443129_7 - - - - 0.0000000000000000000000000001177 121.0
PYH1_k127_2443129_8 - - - - 0.000000000000000000002895 96.0
PYH1_k127_2449113_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1065.0
PYH1_k127_2449113_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
PYH1_k127_2449113_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000009482 229.0
PYH1_k127_2449113_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000006447 197.0
PYH1_k127_2449113_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000001068 171.0
PYH1_k127_2449113_5 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000002592 127.0
PYH1_k127_2449113_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000006835 94.0
PYH1_k127_2449113_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000006258 85.0
PYH1_k127_2460754_0 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000003543 207.0
PYH1_k127_2460754_1 CAAX protease self-immunity K07052 - - 0.000000000000000000007533 101.0
PYH1_k127_250505_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 494.0
PYH1_k127_250505_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 332.0
PYH1_k127_250505_2 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001081 261.0
PYH1_k127_250505_3 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.0003267 46.0
PYH1_k127_2512452_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.897e-214 681.0
PYH1_k127_2512452_1 protein conserved in bacteria K03690 - - 0.000000000000000000001296 98.0
PYH1_k127_2512861_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.867e-196 619.0
PYH1_k127_2512861_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 371.0
PYH1_k127_2523505_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001498 265.0
PYH1_k127_2577966_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
PYH1_k127_2577966_1 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007663 256.0
PYH1_k127_2577966_2 Large family of predicted nucleotide-binding domains K07175 - - 0.00000000000000000000000000000000000000000000000001551 183.0
PYH1_k127_2593174_0 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
PYH1_k127_2593174_1 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
PYH1_k127_2593174_2 Binding-protein-dependent transport system inner membrane component K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001999 287.0
PYH1_k127_2593174_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000001092 111.0
PYH1_k127_2601302_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 610.0
PYH1_k127_2601302_1 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 541.0
PYH1_k127_2601302_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001008 294.0
PYH1_k127_2601302_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
PYH1_k127_2601302_4 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
PYH1_k127_2601302_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000005514 171.0
PYH1_k127_2601302_6 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000001169 131.0
PYH1_k127_2601302_7 Protein of unknown function (DUF3460) - - - 0.0000000000003698 73.0
PYH1_k127_2615970_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.001e-204 643.0
PYH1_k127_2615970_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
PYH1_k127_2615970_2 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 361.0
PYH1_k127_2615970_3 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 317.0
PYH1_k127_2615970_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004661 253.0
PYH1_k127_2615970_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009957 263.0
PYH1_k127_2615970_6 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
PYH1_k127_2615970_7 Rhodanese-like domain - - - 0.000000000000000000000000000799 125.0
PYH1_k127_2615970_8 Bacterial SH3 domain - - - 0.0000000000000000000004618 110.0
PYH1_k127_2628309_0 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.633e-244 764.0
PYH1_k127_2628309_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 467.0
PYH1_k127_2628309_2 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 404.0
PYH1_k127_2628309_3 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 405.0
PYH1_k127_2628309_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 350.0
PYH1_k127_2643476_0 TIGRFAM type I secretion system ATPase K06148,K12536 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 588.0
PYH1_k127_2643476_1 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
PYH1_k127_265576_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.494e-296 938.0
PYH1_k127_265576_1 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
PYH1_k127_265576_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 410.0
PYH1_k127_265576_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
PYH1_k127_265576_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 383.0
PYH1_k127_265576_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 391.0
PYH1_k127_265576_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
PYH1_k127_2656144_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1012.0
PYH1_k127_2656144_1 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 395.0
PYH1_k127_2656144_2 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 349.0
PYH1_k127_2656144_3 - - - - 0.00000000000003452 75.0
PYH1_k127_2656144_4 - - - - 0.00000000003358 73.0
PYH1_k127_2673007_0 Peptidase S24-like - - - 0.000000000000000000000000000000000004262 142.0
PYH1_k127_2673007_1 - - - - 0.0000000000000000000000000000000003871 134.0
PYH1_k127_2673007_2 - - - - 0.000000000000000562 84.0
PYH1_k127_2673007_3 - - - - 0.00000000000003214 81.0
PYH1_k127_2687040_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 9.542e-225 704.0
PYH1_k127_2687040_1 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000001226 211.0
PYH1_k127_2687040_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000005519 178.0
PYH1_k127_2687040_3 Ribosomal protein S18 K02963 - - 0.00000000000000000000000000000000006314 134.0
PYH1_k127_2687631_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 9.504e-241 755.0
PYH1_k127_2687631_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 443.0
PYH1_k127_2687631_2 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 388.0
PYH1_k127_2687631_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006018 258.0
PYH1_k127_2687631_4 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000004946 190.0
PYH1_k127_2713967_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 441.0
PYH1_k127_2713967_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 442.0
PYH1_k127_2713967_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
PYH1_k127_2713967_3 PIN domain - - - 0.00000000000000000000000000000000000000000000009327 172.0
PYH1_k127_2713967_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000003339 155.0
PYH1_k127_2713967_5 positive regulation of growth K01081 - 3.1.3.5 0.00000000000000000000000001165 110.0
PYH1_k127_2714258_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 582.0
PYH1_k127_2714258_1 Belongs to the globin family - - - 0.000000000000000000000000008218 117.0
PYH1_k127_2714258_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000003845 55.0
PYH1_k127_2714258_3 Cytochrome c - - - 0.0005763 44.0
PYH1_k127_2759602_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1641.0
PYH1_k127_2759602_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 535.0
PYH1_k127_2759602_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002059 171.0
PYH1_k127_2764728_0 - - - - 0.00000000001063 77.0
PYH1_k127_2764728_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0006584 46.0
PYH1_k127_2769663_0 Large family of predicted nucleotide-binding domains K07175 - - 3.991e-214 668.0
PYH1_k127_2769663_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 333.0
PYH1_k127_2771447_0 cytochrome - - - 1.679e-254 795.0
PYH1_k127_2771447_1 4Fe-4S single cluster domain - - - 8.715e-226 703.0
PYH1_k127_2771447_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 427.0
PYH1_k127_2771447_3 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
PYH1_k127_2771447_4 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000491 207.0
PYH1_k127_2771447_5 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
PYH1_k127_2772717_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 541.0
PYH1_k127_2772717_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 526.0
PYH1_k127_2772717_2 Thermostable hemolysin - - - 0.000000000000000000000000000000000000000000002597 172.0
PYH1_k127_2772717_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000009103 163.0
PYH1_k127_2774731_0 His Kinase A (phosphoacceptor) domain K19661 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 543.0
PYH1_k127_2774731_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
PYH1_k127_2774731_2 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000003431 205.0
PYH1_k127_2774731_3 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000000000000006505 172.0
PYH1_k127_2774731_4 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000008212 144.0
PYH1_k127_2780476_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1069.0
PYH1_k127_2780476_1 type IV pilus secretin PilQ K02666 - - 2.617e-228 741.0
PYH1_k127_2780476_2 Type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 529.0
PYH1_k127_2780476_3 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
PYH1_k127_2780476_4 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000001097 207.0
PYH1_k127_2780476_5 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000002635 180.0
PYH1_k127_2780476_6 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000003799 185.0
PYH1_k127_2780476_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000004887 110.0
PYH1_k127_2782406_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 8.596e-243 761.0
PYH1_k127_2782406_1 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
PYH1_k127_2782406_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 319.0
PYH1_k127_2786245_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 9.653e-287 894.0
PYH1_k127_2786245_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 406.0
PYH1_k127_2786245_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 349.0
PYH1_k127_2786245_3 4Fe-4S ferredoxin K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 331.0
PYH1_k127_2786245_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002998 263.0
PYH1_k127_2786245_5 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
PYH1_k127_2786245_6 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001169 248.0
PYH1_k127_2786245_7 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002583 224.0
PYH1_k127_2800142_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1009.0
PYH1_k127_2800142_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
PYH1_k127_2800142_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 323.0
PYH1_k127_2800142_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000003984 255.0
PYH1_k127_2800142_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
PYH1_k127_2800142_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001837 150.0
PYH1_k127_2800142_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000004456 77.0
PYH1_k127_2853102_0 PFAM Peptidase M16 K07263 - - 1.044e-210 662.0
PYH1_k127_2853102_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 535.0
PYH1_k127_2853102_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000004155 241.0
PYH1_k127_2853102_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001521 214.0
PYH1_k127_2853102_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000001511 208.0
PYH1_k127_2853102_5 Ferredoxin - - - 0.00000000000000000000000000000000000004365 143.0
PYH1_k127_2853102_6 Ankyrin repeats (many copies) - GO:0003008,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0007010,GO:0007015,GO:0007600,GO:0007605,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0032420,GO:0032421,GO:0032426,GO:0032501,GO:0042995,GO:0043005,GO:0043226,GO:0044085,GO:0044422,GO:0044424,GO:0044463,GO:0044464,GO:0044877,GO:0050877,GO:0050954,GO:0051015,GO:0051017,GO:0061572,GO:0071840,GO:0097435,GO:0097458,GO:0098858,GO:0098862,GO:0120025,GO:0120038 - 0.00009613 48.0
PYH1_k127_2856675_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 532.0
PYH1_k127_2856675_1 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 477.0
PYH1_k127_2856675_2 Zinc-finger domain - - - 0.0000000000000000000000000002722 114.0
PYH1_k127_2856675_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000002348 95.0
PYH1_k127_2857285_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.237e-224 699.0
PYH1_k127_2857285_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 462.0
PYH1_k127_2857285_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 374.0
PYH1_k127_2857285_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
PYH1_k127_2857285_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000002267 149.0
PYH1_k127_2859053_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 573.0
PYH1_k127_2859053_1 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
PYH1_k127_2859053_10 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000361 93.0
PYH1_k127_2859053_11 peptidase activity - - - 0.000001533 53.0
PYH1_k127_2859053_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
PYH1_k127_2859053_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000007803 189.0
PYH1_k127_2859053_4 Trypsin - - - 0.000000000000000000000000000000000000000000000002197 191.0
PYH1_k127_2859053_5 - - - - 0.00000000000000000000000000000000000000001651 160.0
PYH1_k127_2859053_6 DsrC like protein - - - 0.00000000000000000000000000000000000000002531 157.0
PYH1_k127_2859053_7 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000904 145.0
PYH1_k127_2859053_8 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003768 109.0
PYH1_k127_2859053_9 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000002958 98.0
PYH1_k127_2861179_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
PYH1_k127_2861179_1 amino acid ABC transporter K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 476.0
PYH1_k127_2861179_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 392.0
PYH1_k127_2861179_3 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 321.0
PYH1_k127_2861179_4 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000002627 223.0
PYH1_k127_2861179_5 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000003237 134.0
PYH1_k127_2877694_0 Domain of unknown function (DUF3400) - - - 0.0 1957.0
PYH1_k127_2877694_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 338.0
PYH1_k127_2877694_2 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000001152 213.0
PYH1_k127_2877694_3 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000001285 177.0
PYH1_k127_2879893_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 436.0
PYH1_k127_2879893_1 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000002018 186.0
PYH1_k127_2884910_0 PFAM FMN-binding domain protein K19339 - - 0.00000000000000000000000000000000000000000000000000000173 199.0
PYH1_k127_2884910_1 - - - - 0.0000000000000000000000000000000000000000000002661 175.0
PYH1_k127_2884910_2 - - - - 0.000000000000005965 81.0
PYH1_k127_2884910_3 TraB family K09973 - - 0.0000004084 53.0
PYH1_k127_2886921_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.255e-270 861.0
PYH1_k127_2886921_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 602.0
PYH1_k127_2886921_2 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 544.0
PYH1_k127_2886921_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 381.0
PYH1_k127_2886921_4 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 344.0
PYH1_k127_2895873_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 1.726e-195 616.0
PYH1_k127_2895873_1 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 378.0
PYH1_k127_2895873_2 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000009585 195.0
PYH1_k127_2895873_3 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000001519 169.0
PYH1_k127_2901777_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 579.0
PYH1_k127_2921577_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 580.0
PYH1_k127_2921577_1 Modulates RecA activity K03565 - - 0.0000000000001266 81.0
PYH1_k127_2921577_2 Belongs to the CinA family K03743 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 0.0001211 45.0
PYH1_k127_2922215_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 436.0
PYH1_k127_2922215_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 354.0
PYH1_k127_2922215_2 TPM domain K08988 - - 0.0000000000000000000000000000000000000001301 152.0
PYH1_k127_2925411_0 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 328.0
PYH1_k127_2925411_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000008692 224.0
PYH1_k127_2925411_2 Gram-negative porin - - - 0.00000000000000000000000000000000000005116 159.0
PYH1_k127_2925411_3 nuclease activity - - - 0.000000000000000000000000000000006358 131.0
PYH1_k127_2925411_5 Protein of unknown function (DUF2283) - - - 0.00000000000000007997 82.0
PYH1_k127_2925411_6 Domain of unknown function (DUF4258) - - - 0.000000000000002503 78.0
PYH1_k127_2927443_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 519.0
PYH1_k127_2927443_1 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000006307 144.0
PYH1_k127_2927443_2 Nad-dependent epimerase dehydratase - - - 0.00000000004232 64.0
PYH1_k127_2941271_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1470.0
PYH1_k127_2941271_1 blue (type 1) copper - - - 0.0000000000000000000000000000001629 128.0
PYH1_k127_2941271_2 negative regulation of establishment of protein localization K02570 - - 0.000000000000000001812 89.0
PYH1_k127_2946834_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.149e-320 998.0
PYH1_k127_2946834_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004741 261.0
PYH1_k127_2946834_2 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000003542 188.0
PYH1_k127_2946834_3 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.00000000000000000000001061 103.0
PYH1_k127_2951334_0 endonuclease activity K07451 - - 0.000000000000000000000000001304 127.0
PYH1_k127_2951334_1 enzyme binding K00567,K07443 - 2.1.1.63 0.00000002972 57.0
PYH1_k127_2951334_2 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.00007865 48.0
PYH1_k127_2951334_3 endonuclease activity K07451 - - 0.0007838 48.0
PYH1_k127_2952188_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 361.0
PYH1_k127_2952188_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000002184 213.0
PYH1_k127_2952188_2 - - - - 0.00000000000000000000000000000000000000000000000009905 201.0
PYH1_k127_2952188_3 Chaperone - - - 0.0000000000000000000000000000000000000000000000001227 188.0
PYH1_k127_2952188_4 - - - - 0.0000000001878 71.0
PYH1_k127_2952188_5 - - - - 0.000000007655 64.0
PYH1_k127_2954532_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 6.271e-239 761.0
PYH1_k127_2954532_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 304.0
PYH1_k127_2958439_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 466.0
PYH1_k127_2958439_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 382.0
PYH1_k127_2958439_2 Major facilitator Superfamily - - - 0.000000000000000000000000000009838 126.0
PYH1_k127_2962394_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000009158 169.0
PYH1_k127_2962394_1 Phasin protein - - - 0.0000000000000000000000000000000000009384 145.0
PYH1_k127_2962394_2 Dioxygenase - - - 0.0000000000000000000000128 105.0
PYH1_k127_2963008_0 homoserine dehydrogenase K00003 - 1.1.1.3 7.614e-229 714.0
PYH1_k127_2963008_1 Threonine synthase K01733 - 4.2.3.1 5.516e-224 702.0
PYH1_k127_2963008_10 Signal Transduction Histidine Kinase - - - 0.00000001398 68.0
PYH1_k127_2963008_2 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 3.103e-221 694.0
PYH1_k127_2963008_3 Aminotransferase class I and II K14261 - - 2.565e-209 655.0
PYH1_k127_2963008_4 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 311.0
PYH1_k127_2963008_5 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002292 245.0
PYH1_k127_2963008_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000121 237.0
PYH1_k127_2963008_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000009987 142.0
PYH1_k127_2963008_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000003595 130.0
PYH1_k127_2963008_9 Putative diguanylate phosphodiesterase - - - 0.00000000000000009614 95.0
PYH1_k127_2979905_0 CoA-binding domain protein K09181 - - 4.932e-252 790.0
PYH1_k127_2999316_0 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009398 245.0
PYH1_k127_2999316_1 PFAM transcription elongation factor GreA GreB - - - 0.00000000000000000000000000000000000000000000007137 178.0
PYH1_k127_2999316_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000002511 64.0
PYH1_k127_2999316_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000002613 56.0
PYH1_k127_3011520_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 541.0
PYH1_k127_3011520_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 494.0
PYH1_k127_3011520_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
PYH1_k127_3011520_3 PFAM membrane protein of K08972 - - 0.0000000000000000000000000000000001477 136.0
PYH1_k127_3011520_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000002593 88.0
PYH1_k127_3012901_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1023.0
PYH1_k127_3012901_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 7.846e-204 646.0
PYH1_k127_3012901_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
PYH1_k127_3012901_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000006091 119.0
PYH1_k127_3012901_4 Domain of unknown function (DUF4845) - - - 0.000000000000000000003672 100.0
PYH1_k127_3012901_5 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.000000000000000000004211 96.0
PYH1_k127_3019437_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 518.0
PYH1_k127_3024751_0 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000013 205.0
PYH1_k127_3024751_1 - - - - 0.00000000000000000000000000000000000000000000000000000001015 208.0
PYH1_k127_3024751_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000001834 173.0
PYH1_k127_3028385_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1013.0
PYH1_k127_3028385_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.327e-283 875.0
PYH1_k127_3028385_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
PYH1_k127_3028385_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000002549 199.0
PYH1_k127_3028385_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000309 138.0
PYH1_k127_3028385_13 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000003048 88.0
PYH1_k127_3028385_14 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000001585 80.0
PYH1_k127_3028385_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.049e-267 829.0
PYH1_k127_3028385_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 6.394e-207 651.0
PYH1_k127_3028385_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
PYH1_k127_3028385_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 401.0
PYH1_k127_3028385_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 391.0
PYH1_k127_3028385_7 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 361.0
PYH1_k127_3028385_8 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000004916 235.0
PYH1_k127_3028385_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000008326 203.0
PYH1_k127_3037053_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 477.0
PYH1_k127_3037053_1 serine threonine protein kinase - - - 0.0000000000000000000000000000003237 128.0
PYH1_k127_3074658_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 316.0
PYH1_k127_3074658_1 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 321.0
PYH1_k127_3074658_2 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006402 264.0
PYH1_k127_3074658_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000008441 229.0
PYH1_k127_3114623_0 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001995 278.0
PYH1_k127_3114623_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002042 239.0
PYH1_k127_3114623_2 HPP family K07168 - - 0.000000006023 57.0
PYH1_k127_3114623_3 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000006245 49.0
PYH1_k127_3123191_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 585.0
PYH1_k127_3123191_1 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
PYH1_k127_3123191_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 408.0
PYH1_k127_3123191_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 372.0
PYH1_k127_3123191_4 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000244 251.0
PYH1_k127_3123191_5 Protein of unknown function (DUF1318) K09978 - - 0.000000000000000000000000000000000000000000000000001049 190.0
PYH1_k127_3123191_6 - - - - 0.0000000001393 64.0
PYH1_k127_3123191_7 Resolvase, N terminal domain - - - 0.000000001134 65.0
PYH1_k127_3123191_8 Biotin-lipoyl like K02005 - - 0.00009807 51.0
PYH1_k127_3123191_9 - - - - 0.0003573 49.0
PYH1_k127_3133408_0 SPTR Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000003046 83.0
PYH1_k127_3133408_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000007548 62.0
PYH1_k127_31448_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 9.489e-209 654.0
PYH1_k127_31448_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 373.0
PYH1_k127_31448_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
PYH1_k127_31448_3 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000004197 207.0
PYH1_k127_3154468_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 1.424e-226 711.0
PYH1_k127_3154468_1 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000002565 196.0
PYH1_k127_3158827_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1334.0
PYH1_k127_3158827_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 571.0
PYH1_k127_3158827_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 544.0
PYH1_k127_3215431_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1554.0
PYH1_k127_3215431_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000001549 216.0
PYH1_k127_3215431_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000958 164.0
PYH1_k127_3215431_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001434 132.0
PYH1_k127_3215431_4 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000003902 110.0
PYH1_k127_3221533_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 591.0
PYH1_k127_3221533_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
PYH1_k127_3221533_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000006918 217.0
PYH1_k127_3221533_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 0.00000000000000000000000000000001854 130.0
PYH1_k127_3237069_0 PQQ-like domain K00114 - 1.1.2.8 7.645e-319 986.0
PYH1_k127_3237069_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
PYH1_k127_3237069_2 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 328.0
PYH1_k127_3237069_3 Sulphur oxidation protein SoxZ K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 298.0
PYH1_k127_3237069_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003327 269.0
PYH1_k127_3237069_5 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005841 266.0
PYH1_k127_3237069_6 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000009765 181.0
PYH1_k127_3237069_7 - - - - 0.00000000000000000006274 96.0
PYH1_k127_3237069_8 Bacterial regulatory protein, Fis family K21405 - - 0.0000000007086 61.0
PYH1_k127_3298489_0 DNA polymerase X family K02347 - - 1.544e-256 802.0
PYH1_k127_3298489_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 343.0
PYH1_k127_3298489_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000005802 143.0
PYH1_k127_3298489_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000003415 123.0
PYH1_k127_3300505_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 530.0
PYH1_k127_3300505_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000001063 173.0
PYH1_k127_3300505_2 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000003318 160.0
PYH1_k127_332131_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.83e-253 784.0
PYH1_k127_332131_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.101e-235 744.0
PYH1_k127_332131_2 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 525.0
PYH1_k127_332131_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
PYH1_k127_332131_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000003053 169.0
PYH1_k127_3327734_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 580.0
PYH1_k127_3327734_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 501.0
PYH1_k127_3327734_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 419.0
PYH1_k127_3327734_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 325.0
PYH1_k127_3327734_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006707 280.0
PYH1_k127_3327734_5 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000000000298 152.0
PYH1_k127_3338130_0 Belongs to the glycosyl hydrolase 57 family - - - 7.989e-241 755.0
PYH1_k127_3338130_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.098e-203 644.0
PYH1_k127_3338130_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000000000000000000000000000000002773 179.0
PYH1_k127_3338130_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000002354 57.0
PYH1_k127_3358160_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 440.0
PYH1_k127_3358160_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 422.0
PYH1_k127_3358160_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
PYH1_k127_3358160_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
PYH1_k127_3358160_4 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
PYH1_k127_3358160_5 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
PYH1_k127_3358160_6 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000002145 126.0
PYH1_k127_3358160_7 response to antibiotic K07122 - - 0.0000000000000005701 89.0
PYH1_k127_3358160_8 ABC transporter K02065 - - 0.00000000000000792 74.0
PYH1_k127_335891_0 NADPH-dependent glutamate synthase beta - - - 2.638e-305 947.0
PYH1_k127_335891_1 Fe-S oxidoreductase K21834 - - 2.162e-267 828.0
PYH1_k127_335891_10 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000002056 201.0
PYH1_k127_335891_11 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000003575 215.0
PYH1_k127_335891_12 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000001172 187.0
PYH1_k127_335891_13 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000005865 188.0
PYH1_k127_335891_14 DsrC like protein - - - 0.000000000000000000000000000000000000000000007216 164.0
PYH1_k127_335891_15 DsrH like protein K07237 - - 0.000000000000000000000000000000388 125.0
PYH1_k127_335891_16 - - - - 0.000000000000000000000000004002 115.0
PYH1_k127_335891_17 - - - - 0.00000000000000000000001008 102.0
PYH1_k127_335891_2 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.12e-220 689.0
PYH1_k127_335891_3 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 1.696e-217 677.0
PYH1_k127_335891_4 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 501.0
PYH1_k127_335891_5 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 357.0
PYH1_k127_335891_6 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 349.0
PYH1_k127_335891_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 354.0
PYH1_k127_335891_8 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000000001699 214.0
PYH1_k127_335891_9 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
PYH1_k127_3367831_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 394.0
PYH1_k127_3367831_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 347.0
PYH1_k127_3367831_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
PYH1_k127_3367831_3 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
PYH1_k127_3367831_4 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002502 242.0
PYH1_k127_3367831_5 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
PYH1_k127_3367831_6 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000003263 188.0
PYH1_k127_3367831_7 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000008477 111.0
PYH1_k127_3406966_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.188e-315 983.0
PYH1_k127_3406966_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 507.0
PYH1_k127_3406966_2 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 311.0
PYH1_k127_3406966_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000009705 185.0
PYH1_k127_3406966_4 transcriptional - - - 0.0000000000000000000000000000000000000000000000006546 178.0
PYH1_k127_3449605_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 499.0
PYH1_k127_3449605_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 393.0
PYH1_k127_3449605_2 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 360.0
PYH1_k127_3450969_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 4.682e-212 662.0
PYH1_k127_3450969_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 406.0
PYH1_k127_3450969_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
PYH1_k127_3450969_3 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.000000000000000000000000000000000000000001609 162.0
PYH1_k127_3450969_4 transcriptional - - - 0.0000000000000000000000000000000000000000187 157.0
PYH1_k127_3464094_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 365.0
PYH1_k127_3464094_1 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000207 278.0
PYH1_k127_3467467_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 522.0
PYH1_k127_3467467_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000199 105.0
PYH1_k127_3479649_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 421.0
PYH1_k127_3479649_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
PYH1_k127_3479649_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000001484 218.0
PYH1_k127_3479649_3 NusG domain II - - - 0.00000000000002869 74.0
PYH1_k127_3508934_0 Malic enzyme K00029 - 1.1.1.40 1.739e-235 740.0
PYH1_k127_3510621_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1140.0
PYH1_k127_3510621_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.913e-295 923.0
PYH1_k127_3510621_2 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 391.0
PYH1_k127_3512566_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 2.82e-200 639.0
PYH1_k127_3512566_1 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 427.0
PYH1_k127_3512566_2 Domain of unknown function (DUF4124) - - - 0.0000001901 54.0
PYH1_k127_3541688_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000116 248.0
PYH1_k127_3541688_1 Phasin protein - - - 0.00000000000002454 78.0
PYH1_k127_3553853_0 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
PYH1_k127_3553853_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 237.0
PYH1_k127_3553853_2 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000001157 172.0
PYH1_k127_3553853_3 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000006597 162.0
PYH1_k127_3553853_4 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.0000000000000000000000000000000000000000005108 160.0
PYH1_k127_3553853_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000003796 70.0
PYH1_k127_3559588_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 503.0
PYH1_k127_3559588_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000004195 244.0
PYH1_k127_3559588_2 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000001172 215.0
PYH1_k127_3559588_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000003802 106.0
PYH1_k127_3582311_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 503.0
PYH1_k127_3585997_0 Von Willebrand factor A K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 596.0
PYH1_k127_3585997_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 422.0
PYH1_k127_3585997_2 acetyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000001066 76.0
PYH1_k127_3586768_0 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 508.0
PYH1_k127_3586768_1 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 398.0
PYH1_k127_3586768_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 352.0
PYH1_k127_3586768_3 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000713 294.0
PYH1_k127_3586768_4 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000597 241.0
PYH1_k127_3586858_0 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 357.0
PYH1_k127_3586858_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 351.0
PYH1_k127_3586858_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000009029 219.0
PYH1_k127_3586858_3 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000008684 211.0
PYH1_k127_3620922_0 Peptidase S8 K08651,K14645 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 529.0
PYH1_k127_3620922_1 type I secretion membrane fusion K02022,K12537 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 335.0
PYH1_k127_3620922_2 Protein of unknown function (DUF3467) - - - 0.0002032 50.0
PYH1_k127_3634612_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 567.0
PYH1_k127_3634612_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
PYH1_k127_3634612_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 342.0
PYH1_k127_3634612_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000002779 228.0
PYH1_k127_3634612_4 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000002718 221.0
PYH1_k127_3634612_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001636 208.0
PYH1_k127_363581_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 6.602e-249 779.0
PYH1_k127_363581_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.594e-215 695.0
PYH1_k127_3660139_0 type IV-A pilus assembly ATPase PilB K02652 - - 4.614e-251 786.0
PYH1_k127_3660139_1 PFAM type II secretion system K02653 - - 1.209e-200 631.0
PYH1_k127_3660139_2 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 571.0
PYH1_k127_3660139_3 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 276.0
PYH1_k127_3668870_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 5.58e-297 921.0
PYH1_k127_3670874_0 FAD binding domain K00394 - 1.8.99.2 0.0 1260.0
PYH1_k127_3670874_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.728e-220 688.0
PYH1_k127_3670874_2 PFAM AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
PYH1_k127_3670874_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
PYH1_k127_3670874_4 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 308.0
PYH1_k127_3670874_5 PFAM von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000009324 168.0
PYH1_k127_3683923_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 474.0
PYH1_k127_3683923_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 330.0
PYH1_k127_3683923_2 metal cluster binding - - - 0.000000000000000000000000000003496 130.0
PYH1_k127_3687158_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 424.0
PYH1_k127_3687158_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
PYH1_k127_3687158_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000001918 85.0
PYH1_k127_3688825_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.14e-260 835.0
PYH1_k127_3688825_1 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000001456 198.0
PYH1_k127_369696_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 535.0
PYH1_k127_369696_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
PYH1_k127_369696_2 SecretomeP prediction - - - 0.000000002186 63.0
PYH1_k127_3717589_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 6.832e-298 923.0
PYH1_k127_3717589_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 1.826e-232 733.0
PYH1_k127_3717589_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 558.0
PYH1_k127_3717589_3 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 508.0
PYH1_k127_3717589_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
PYH1_k127_3717589_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000008897 222.0
PYH1_k127_3717589_6 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000007614 195.0
PYH1_k127_3717589_7 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000005587 151.0
PYH1_k127_3717589_8 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000004558 110.0
PYH1_k127_3717589_9 General secretory system II protein E domain protein K02454 - - 0.0000000000000000002454 87.0
PYH1_k127_3723353_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.941e-248 775.0
PYH1_k127_3723353_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 1.862e-200 627.0
PYH1_k127_3723353_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 322.0
PYH1_k127_3723353_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000005529 233.0
PYH1_k127_3723353_4 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000003127 164.0
PYH1_k127_3723353_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000008188 135.0
PYH1_k127_374272_0 Acts as a magnesium transporter K06213 - - 2.61e-210 663.0
PYH1_k127_374272_1 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000005007 209.0
PYH1_k127_3759667_0 MMPL family - - - 0.0 1331.0
PYH1_k127_3773135_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1011.0
PYH1_k127_3773135_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 3.427e-194 617.0
PYH1_k127_3773135_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 513.0
PYH1_k127_3773135_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 454.0
PYH1_k127_3773135_4 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
PYH1_k127_3773135_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 419.0
PYH1_k127_3773135_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
PYH1_k127_3773135_7 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 381.0
PYH1_k127_3773587_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 590.0
PYH1_k127_3773587_1 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 293.0
PYH1_k127_3773587_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001199 272.0
PYH1_k127_3773587_3 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000003625 162.0
PYH1_k127_3773587_4 - - - - 0.0008684 44.0
PYH1_k127_3824374_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.391e-227 707.0
PYH1_k127_3824374_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
PYH1_k127_3824374_2 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 315.0
PYH1_k127_3824374_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
PYH1_k127_3824374_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009301 261.0
PYH1_k127_3824374_5 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000002394 208.0
PYH1_k127_3857747_0 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 337.0
PYH1_k127_3857747_1 SpoIIAA-like - - - 0.000000000000000000000000000000000000007459 153.0
PYH1_k127_3857747_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0003116 44.0
PYH1_k127_3875909_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
PYH1_k127_3875909_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002366 261.0
PYH1_k127_3876978_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
PYH1_k127_3876978_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003591 259.0
PYH1_k127_3887353_0 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 416.0
PYH1_k127_3887353_1 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
PYH1_k127_3887353_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001089 254.0
PYH1_k127_3887353_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000937 215.0
PYH1_k127_3887353_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
PYH1_k127_3895854_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
PYH1_k127_3895854_1 LemA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 280.0
PYH1_k127_3895854_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
PYH1_k127_3895854_3 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
PYH1_k127_3895854_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002331 218.0
PYH1_k127_3895854_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
PYH1_k127_3895854_6 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
PYH1_k127_3895854_7 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000002807 57.0
PYH1_k127_3895854_8 Glycine zipper 2TM domain - - - 0.00000009868 60.0
PYH1_k127_3902137_0 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000001228 203.0
PYH1_k127_3902137_1 anaerobic respiration - - - 0.00000000000000000000000000000000000000005799 160.0
PYH1_k127_3902137_2 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000007825 130.0
PYH1_k127_3908418_0 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 605.0
PYH1_k127_3908418_1 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 486.0
PYH1_k127_3908418_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 480.0
PYH1_k127_3908418_3 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 469.0
PYH1_k127_3910040_0 Belongs to the GARS family K01945 - 6.3.4.13 6.547e-204 642.0
PYH1_k127_3910040_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 469.0
PYH1_k127_3952865_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 400.0
PYH1_k127_3952865_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 368.0
PYH1_k127_3990431_0 Sulfate transporter antisigma-factor antagonist STAS - - - 8.037e-245 767.0
PYH1_k127_3990431_1 STAS domain K03321 - - 1.505e-231 733.0
PYH1_k127_3990431_2 Chromate transporter K07240 - - 9.694e-200 635.0
PYH1_k127_3990431_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 323.0
PYH1_k127_3990431_4 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
PYH1_k127_3990431_5 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000000000000000000000002384 201.0
PYH1_k127_3990431_6 Ethylbenzene dehydrogenase - - - 0.0000000000000000000004384 107.0
PYH1_k127_3990431_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000003237 82.0
PYH1_k127_3990431_8 Protein tyrosine kinase - - - 0.0001681 52.0
PYH1_k127_4011541_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 602.0
PYH1_k127_4011541_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 479.0
PYH1_k127_4011541_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000001918 73.0
PYH1_k127_4057386_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 565.0
PYH1_k127_4057386_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
PYH1_k127_4057386_2 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 388.0
PYH1_k127_4057386_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
PYH1_k127_4057806_0 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 572.0
PYH1_k127_4057806_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 430.0
PYH1_k127_4057806_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 395.0
PYH1_k127_4057806_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000006053 190.0
PYH1_k127_4057806_4 - - - - 0.0000000000000000000000000001415 119.0
PYH1_k127_4062203_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1515.0
PYH1_k127_4062203_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
PYH1_k127_4062203_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000002722 127.0
PYH1_k127_4063475_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 9.083e-214 670.0
PYH1_k127_4063475_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000001048 143.0
PYH1_k127_4063475_2 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000009091 61.0
PYH1_k127_409211_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.767e-212 666.0
PYH1_k127_409211_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH1_k127_409211_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000001856 183.0
PYH1_k127_4093990_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 472.0
PYH1_k127_4093990_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 280.0
PYH1_k127_4120444_0 AAA domain - - - 7.824e-194 617.0
PYH1_k127_4122894_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 394.0
PYH1_k127_4122894_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000002412 194.0
PYH1_k127_4122894_2 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.0000000000000000000000000000006386 126.0
PYH1_k127_4122894_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000001986 87.0
PYH1_k127_4140486_0 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 453.0
PYH1_k127_4140486_1 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000145 167.0
PYH1_k127_4140919_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 5.368e-201 631.0
PYH1_k127_4140919_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 486.0
PYH1_k127_4140919_10 - - - - 0.0000000000007549 70.0
PYH1_k127_4140919_2 Major facilitator Superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 460.0
PYH1_k127_4140919_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 453.0
PYH1_k127_4140919_4 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 375.0
PYH1_k127_4140919_5 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
PYH1_k127_4140919_6 Dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000002668 195.0
PYH1_k127_4140919_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001372 139.0
PYH1_k127_4140919_8 Ammonium transporter K03320,K06580 - - 0.00000000000000000000000001519 109.0
PYH1_k127_4140919_9 TIR domain - - - 0.0000000000000000000000006021 118.0
PYH1_k127_4150823_0 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 601.0
PYH1_k127_4150823_1 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000005046 128.0
PYH1_k127_4152496_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 405.0
PYH1_k127_4152496_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003018 173.0
PYH1_k127_4152496_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000001698 143.0
PYH1_k127_417751_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.092e-289 895.0
PYH1_k127_417751_1 Sodium:solute symporter family - - - 6.102e-284 889.0
PYH1_k127_417751_2 SMART CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 616.0
PYH1_k127_417751_3 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 481.0
PYH1_k127_417751_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000007351 169.0
PYH1_k127_417751_5 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000005619 157.0
PYH1_k127_417751_6 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000004874 146.0
PYH1_k127_417790_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 482.0
PYH1_k127_417790_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 308.0
PYH1_k127_418366_0 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001301 222.0
PYH1_k127_418366_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000002762 139.0
PYH1_k127_419162_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 395.0
PYH1_k127_419162_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 361.0
PYH1_k127_419162_2 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000001875 118.0
PYH1_k127_419162_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000002723 111.0
PYH1_k127_4243842_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1149.0
PYH1_k127_4243842_1 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000005008 198.0
PYH1_k127_4243842_2 DNA recombination-mediator protein A K04096 - - 0.00000000000005343 72.0
PYH1_k127_4244528_0 AAA ATPase central domain protein K07478 - - 7.741e-221 691.0
PYH1_k127_4244528_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.254e-209 657.0
PYH1_k127_4244528_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 604.0
PYH1_k127_4244528_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
PYH1_k127_4244528_4 Helix-turn-helix type 11 - - - 0.0000000000000000000000000000000000000000007183 158.0
PYH1_k127_4271850_0 Male sterility - - - 5.132e-284 887.0
PYH1_k127_4271850_1 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000001964 152.0
PYH1_k127_4271850_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000005086 134.0
PYH1_k127_4271850_3 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000003032 136.0
PYH1_k127_4306809_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.5e-323 997.0
PYH1_k127_4306809_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
PYH1_k127_4306809_2 Planctomycete cytochrome C - - - 0.0000000000000000000000000000001809 128.0
PYH1_k127_4306809_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000634 82.0
PYH1_k127_4306809_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000004104 72.0
PYH1_k127_4314834_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 590.0
PYH1_k127_4314834_1 - - - - 0.00000000000000000001179 99.0
PYH1_k127_4326127_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1213.0
PYH1_k127_4326127_1 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000003386 68.0
PYH1_k127_4333664_0 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 303.0
PYH1_k127_4333664_1 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000002182 252.0
PYH1_k127_4341118_0 Cysteine-rich domain - - - 2.95e-228 717.0
PYH1_k127_4341118_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 568.0
PYH1_k127_4341118_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 520.0
PYH1_k127_4341118_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
PYH1_k127_4341118_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
PYH1_k127_4341118_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000004008 213.0
PYH1_k127_4341118_6 CNP1-like family - - - 0.0000000000000000000000000000000000005759 161.0
PYH1_k127_4341118_7 Protein of unknown function (DUF3617) - - - 0.0000000000000004357 92.0
PYH1_k127_4345230_0 Formyl transferase K19640 - - 6.795e-205 648.0
PYH1_k127_4345230_1 Belongs to the HypD family K04654 - - 9.138e-199 628.0
PYH1_k127_4345230_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 583.0
PYH1_k127_4345230_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000001131 193.0
PYH1_k127_4345230_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000001181 117.0
PYH1_k127_4363011_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 468.0
PYH1_k127_4363011_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 304.0
PYH1_k127_4364150_0 elongation factor G K02355 - - 5e-324 1005.0
PYH1_k127_4364150_1 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
PYH1_k127_4364150_2 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
PYH1_k127_4364150_3 Lipase maturation factor - - - 0.000000000000000000000000000000000000001679 154.0
PYH1_k127_4364150_4 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000008404 145.0
PYH1_k127_4364150_5 - - - - 0.00000000000000000000000000000001337 128.0
PYH1_k127_4380211_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
PYH1_k127_4380211_1 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000005422 242.0
PYH1_k127_43891_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 460.0
PYH1_k127_43891_1 Involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 337.0
PYH1_k127_4475462_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000002431 244.0
PYH1_k127_4475462_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000001045 210.0
PYH1_k127_4475462_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000001148 117.0
PYH1_k127_4475462_3 Belongs to the UPF0434 family K09791 - - 0.000000000000000000002749 99.0
PYH1_k127_4498248_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1428.0
PYH1_k127_4498248_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 475.0
PYH1_k127_4498248_2 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 471.0
PYH1_k127_4498248_3 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 383.0
PYH1_k127_4498248_4 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000001134 95.0
PYH1_k127_4498248_5 - - - - 0.00000001079 58.0
PYH1_k127_4498248_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000001171 52.0
PYH1_k127_4515941_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1570.0
PYH1_k127_4515941_1 Sugar (and other) transporter - - - 5.996e-202 642.0
PYH1_k127_4515941_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 461.0
PYH1_k127_4515941_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
PYH1_k127_4526432_0 SNARE associated Golgi protein - - - 0.0 1041.0
PYH1_k127_4526432_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 561.0
PYH1_k127_4526432_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 447.0
PYH1_k127_4526432_3 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 326.0
PYH1_k127_4526432_4 ABC transporter K06158 - - 0.000000000000000000000002477 106.0
PYH1_k127_4530764_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 401.0
PYH1_k127_4530764_1 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 287.0
PYH1_k127_4530764_2 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000003504 184.0
PYH1_k127_4530764_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.0000000000000000005243 100.0
PYH1_k127_4541063_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.313e-272 847.0
PYH1_k127_4541063_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 615.0
PYH1_k127_4541063_2 dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 306.0
PYH1_k127_4541063_3 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000006027 149.0
PYH1_k127_4554857_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 473.0
PYH1_k127_4554857_1 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 295.0
PYH1_k127_4554857_2 Resolvase - - - 0.000000389 53.0
PYH1_k127_4571545_0 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 451.0
PYH1_k127_4571545_1 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001974 275.0
PYH1_k127_4571545_2 lipid carrier protein - - - 0.00000000000000000000000000000000007597 137.0
PYH1_k127_4575705_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 9.644e-225 709.0
PYH1_k127_4575705_1 glutaminyl-tRNA K01886 - 6.1.1.18 2.808e-221 695.0
PYH1_k127_4575705_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
PYH1_k127_4575705_3 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
PYH1_k127_4575705_4 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
PYH1_k127_4575705_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
PYH1_k127_4575705_6 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
PYH1_k127_4575705_7 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000007464 112.0
PYH1_k127_4575705_8 - - - - 0.0002787 48.0
PYH1_k127_4577729_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 382.0
PYH1_k127_4577729_1 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 357.0
PYH1_k127_4577729_2 Polysaccharide biosynthesis protein K08679,K17947 - 5.1.3.25,5.1.3.6 0.0006911 42.0
PYH1_k127_4582738_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 606.0
PYH1_k127_4582738_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 408.0
PYH1_k127_4582738_2 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 374.0
PYH1_k127_4582738_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
PYH1_k127_4582738_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001003 237.0
PYH1_k127_4582738_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000002307 143.0
PYH1_k127_4613073_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 469.0
PYH1_k127_4613073_1 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 332.0
PYH1_k127_4613073_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000006192 235.0
PYH1_k127_4613073_3 tellurite resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000193 216.0
PYH1_k127_4613073_4 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.00000000000000000000000000000000000000000000007804 177.0
PYH1_k127_4677319_0 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001978 252.0
PYH1_k127_4677319_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000005657 202.0
PYH1_k127_4680545_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003291 277.0
PYH1_k127_4680545_1 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001489 261.0
PYH1_k127_4680545_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
PYH1_k127_4680545_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000008376 83.0
PYH1_k127_4685260_0 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 426.0
PYH1_k127_4685260_1 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002179 271.0
PYH1_k127_4685260_2 MaoC like domain - - - 0.000000000000000000000000000000000000000006294 171.0
PYH1_k127_4688207_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1254.0
PYH1_k127_4688207_1 signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000003251 252.0
PYH1_k127_4688207_2 PFAM response regulator receiver K15012 - - 0.0000000000000000000000000000000000000000000000000000000007536 209.0
PYH1_k127_4688207_3 LuxR family transcriptional regulator K13041 - - 0.00000000000002822 74.0
PYH1_k127_4690181_0 transposase - - - 0.0000000000000000000000000000000000000000000000000000000000001779 229.0
PYH1_k127_4690181_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000001796 54.0
PYH1_k127_4691937_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 492.0
PYH1_k127_4691937_1 abc transporter K06158 - - 0.00000000002273 66.0
PYH1_k127_4697499_0 Iron-sulfur cluster-binding domain K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 557.0
PYH1_k127_4697499_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 389.0
PYH1_k127_4697499_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000002779 228.0
PYH1_k127_4697499_3 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000001083 196.0
PYH1_k127_4700082_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
PYH1_k127_4700082_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000002628 211.0
PYH1_k127_4700082_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000004918 160.0
PYH1_k127_4724780_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 575.0
PYH1_k127_4724780_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000007997 121.0
PYH1_k127_4734006_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 9.44e-210 660.0
PYH1_k127_4734006_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 298.0
PYH1_k127_4734006_2 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002159 258.0
PYH1_k127_4734006_3 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
PYH1_k127_4740774_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.28e-302 940.0
PYH1_k127_4740774_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 360.0
PYH1_k127_4740774_2 SMART ATP-binding region ATPase domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000004619 127.0
PYH1_k127_474841_0 von Willebrand factor, type A - - - 0.0 1185.0
PYH1_k127_474841_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.415e-196 613.0
PYH1_k127_474841_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 567.0
PYH1_k127_474841_3 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
PYH1_k127_474841_4 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
PYH1_k127_474841_5 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
PYH1_k127_474841_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000589 96.0
PYH1_k127_474841_7 - - - - 0.000000000000000001754 91.0
PYH1_k127_4749949_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 3.71e-277 867.0
PYH1_k127_4749949_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000004927 74.0
PYH1_k127_4752745_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 313.0
PYH1_k127_4752745_1 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002291 267.0
PYH1_k127_4752745_2 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000001703 143.0
PYH1_k127_4752745_3 Rhs Element Vgr Protein - - - 0.0000000000000000000000000004646 115.0
PYH1_k127_4758419_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 3.805e-297 918.0
PYH1_k127_4758419_1 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 314.0
PYH1_k127_4766317_0 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 604.0
PYH1_k127_4766317_1 transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 539.0
PYH1_k127_4766317_2 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 367.0
PYH1_k127_4766317_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005023 278.0
PYH1_k127_4766317_4 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000502 202.0
PYH1_k127_4766317_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000004372 165.0
PYH1_k127_4779513_0 Esterase of the alpha-beta hydrolase superfamily - - - 7.097e-196 633.0
PYH1_k127_4779513_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001376 224.0
PYH1_k127_4779513_2 Patatin-like phospholipase - - - 0.0000000000000000005914 94.0
PYH1_k127_4779513_3 Tetratricopeptide repeat - - - 0.0000000004463 62.0
PYH1_k127_4779513_4 transcriptional regulator, SARP family - - - 0.000002324 59.0
PYH1_k127_4779513_5 TIR domain - - - 0.00009022 54.0
PYH1_k127_4790149_0 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
PYH1_k127_4790149_1 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000009769 133.0
PYH1_k127_4790149_2 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000000000000000000001013 108.0
PYH1_k127_4790149_3 Rubredoxin - - - 0.00000000000000000000002218 109.0
PYH1_k127_4790149_4 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000005727 94.0
PYH1_k127_4796074_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 570.0
PYH1_k127_4796074_1 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 366.0
PYH1_k127_4796074_2 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
PYH1_k127_4796074_3 amp-dependent synthetase and ligase - - - 0.00000000000000003668 84.0
PYH1_k127_4797612_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.222e-320 986.0
PYH1_k127_4797612_1 PFAM Cysteine-rich - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 516.0
PYH1_k127_4797612_2 - - - - 0.0000000000000000003272 91.0
PYH1_k127_4799107_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.103e-274 848.0
PYH1_k127_4799107_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 602.0
PYH1_k127_4799107_2 Cytochrome c oxidase, subunit K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 387.0
PYH1_k127_4799107_3 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 337.0
PYH1_k127_4799107_4 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000002601 159.0
PYH1_k127_4799107_5 FixH K09926 - - 0.00000000000000000000008799 107.0
PYH1_k127_4799107_6 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000001559 79.0
PYH1_k127_4799107_7 Cbb3-type cytochrome oxidase K00407 - - 0.00000000001071 69.0
PYH1_k127_4801878_0 Multicopper oxidase K22349 - 1.16.3.3 5.02e-206 660.0
PYH1_k127_4821626_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.03e-292 910.0
PYH1_k127_4821626_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 314.0
PYH1_k127_4821626_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000003002 171.0
PYH1_k127_4843522_0 PFAM Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 362.0
PYH1_k127_4843522_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 324.0
PYH1_k127_4843522_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000002778 52.0
PYH1_k127_4872386_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.003e-214 672.0
PYH1_k127_4872386_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000001746 237.0
PYH1_k127_4872386_2 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000007192 150.0
PYH1_k127_4888736_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 8.414e-277 858.0
PYH1_k127_4888736_1 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 504.0
PYH1_k127_4888736_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002109 259.0
PYH1_k127_4890200_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 565.0
PYH1_k127_4890200_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000007071 104.0
PYH1_k127_4890200_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000176 93.0
PYH1_k127_4890200_3 - - - - 0.00000934 48.0
PYH1_k127_4905799_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
PYH1_k127_4905799_1 Molybdenum ABC transporter K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
PYH1_k127_4905799_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000002702 79.0
PYH1_k127_4911527_0 Transport of potassium into the cell K03549 - - 1.871e-273 853.0
PYH1_k127_4911527_1 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000005552 151.0
PYH1_k127_4941213_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 535.0
PYH1_k127_4941213_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 372.0
PYH1_k127_4941213_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007665 256.0
PYH1_k127_4941213_3 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000003314 96.0
PYH1_k127_4942445_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 611.0
PYH1_k127_4942445_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 532.0
PYH1_k127_4942445_2 Transcriptional regulator K15539 - - 0.000000000000000000001064 96.0
PYH1_k127_4946112_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 2.137e-242 755.0
PYH1_k127_4946112_1 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
PYH1_k127_4946112_10 - - - - 0.00000000002171 68.0
PYH1_k127_4946112_2 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002046 270.0
PYH1_k127_4946112_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
PYH1_k127_4946112_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000006998 199.0
PYH1_k127_4946112_5 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000001392 168.0
PYH1_k127_4946112_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000003609 152.0
PYH1_k127_4946112_7 psiF repeat - - - 0.00000000000000000001688 102.0
PYH1_k127_4946112_8 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000173 85.0
PYH1_k127_4946112_9 KTSC domain - - - 0.000000000000000009446 85.0
PYH1_k127_4954122_0 Malic enzyme K00029 - 1.1.1.40 0.0 1077.0
PYH1_k127_4954122_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
PYH1_k127_4954122_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 284.0
PYH1_k127_4954122_3 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
PYH1_k127_4954122_4 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000002265 153.0
PYH1_k127_4954122_5 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001151 144.0
PYH1_k127_4954122_6 - - - - 0.00000000000001998 80.0
PYH1_k127_4954122_7 Outer membrane lipoprotein K07285 - - 0.0006833 51.0
PYH1_k127_4960391_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.688e-227 712.0
PYH1_k127_4960391_1 Peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000009176 248.0
PYH1_k127_4960391_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
PYH1_k127_4981691_0 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
PYH1_k127_4981691_1 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000001031 218.0
PYH1_k127_4981691_2 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000003377 157.0
PYH1_k127_4981691_3 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000008 135.0
PYH1_k127_4981691_4 Acetyltransferase (GNAT) domain K02348 - - 0.000000003358 58.0
PYH1_k127_4986585_0 Histidine kinase - - - 4.778e-219 696.0
PYH1_k127_4986585_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
PYH1_k127_4986585_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000705 196.0
PYH1_k127_4986585_3 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000003854 180.0
PYH1_k127_4986585_4 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000007862 126.0
PYH1_k127_4986585_5 Putative zinc-finger - - - 0.000000000001084 72.0
PYH1_k127_4986585_6 - - - - 0.00000001124 63.0
PYH1_k127_4998051_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.907e-220 689.0
PYH1_k127_5003765_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 4.296e-208 659.0
PYH1_k127_5003765_1 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 438.0
PYH1_k127_5003765_2 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000008235 150.0
PYH1_k127_5003765_3 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000001391 143.0
PYH1_k127_5003765_4 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000431 116.0
PYH1_k127_5003765_5 Fe-S protein K06938 - - 0.00000000004691 66.0
PYH1_k127_5010403_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 347.0
PYH1_k127_5010403_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
PYH1_k127_5010403_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003791 179.0
PYH1_k127_5010403_3 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000002077 129.0
PYH1_k127_5019315_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1230.0
PYH1_k127_5019315_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 356.0
PYH1_k127_5019315_2 regulatory protein Crp K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002827 265.0
PYH1_k127_5019315_3 methyltransferase K03437 - - 0.000000000000000001956 87.0
PYH1_k127_5019315_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.000001727 54.0
PYH1_k127_5045780_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 461.0
PYH1_k127_5045780_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 383.0
PYH1_k127_5045780_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 323.0
PYH1_k127_5045780_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
PYH1_k127_5045780_4 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
PYH1_k127_5045780_5 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002005 246.0
PYH1_k127_5045780_6 Part of a membrane complex involved in electron transport K03615 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - 0.00000000000000000000000000000001066 139.0
PYH1_k127_5048458_0 TIGRFAM transposase, IS605 OrfB K07496 - - 0.0000000000000000000000000000000000000000000000000000002663 211.0
PYH1_k127_5048458_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000002053 58.0
PYH1_k127_5048458_2 DNA-binding domain - - - 0.00000009573 56.0
PYH1_k127_5053593_0 Multicopper oxidase K22349 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 516.0
PYH1_k127_5053593_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 337.0
PYH1_k127_5053593_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 327.0
PYH1_k127_5053593_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000004907 193.0
PYH1_k127_5053593_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000003538 138.0
PYH1_k127_5053593_5 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000005616 132.0
PYH1_k127_5063916_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.713e-222 701.0
PYH1_k127_5063916_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 509.0
PYH1_k127_5063916_2 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
PYH1_k127_5063916_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000055 292.0
PYH1_k127_5063916_4 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004964 242.0
PYH1_k127_5063916_5 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000004911 192.0
PYH1_k127_5063916_6 MazG-like family - - - 0.0000000000000000000000000000000004216 138.0
PYH1_k127_5063916_7 Protein of unknown function (DUF465) K09794 - - 0.000000006148 63.0
PYH1_k127_5073213_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 502.0
PYH1_k127_5073213_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
PYH1_k127_5073213_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000007552 177.0
PYH1_k127_5073213_3 - - - - 0.000000000000001389 79.0
PYH1_k127_508317_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1089.0
PYH1_k127_508317_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
PYH1_k127_508317_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000001233 199.0
PYH1_k127_508317_3 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000005267 161.0
PYH1_k127_5102687_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 344.0
PYH1_k127_5102687_1 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000002196 236.0
PYH1_k127_5102687_2 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000619 183.0
PYH1_k127_5102687_3 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000002764 175.0
PYH1_k127_513824_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.712e-252 786.0
PYH1_k127_513824_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
PYH1_k127_513824_2 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000001086 261.0
PYH1_k127_5146187_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 503.0
PYH1_k127_5146187_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 344.0
PYH1_k127_5146187_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000096 288.0
PYH1_k127_5147706_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 532.0
PYH1_k127_5147706_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000006168 235.0
PYH1_k127_5147706_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000004514 57.0
PYH1_k127_5161354_0 Isocitrate lyase K01637 - 4.1.3.1 4.897e-249 774.0
PYH1_k127_5161354_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.817e-207 653.0
PYH1_k127_5161354_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 582.0
PYH1_k127_5161354_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
PYH1_k127_5161354_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000004745 205.0
PYH1_k127_5161354_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000003086 196.0
PYH1_k127_516274_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 379.0
PYH1_k127_516274_1 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 334.0
PYH1_k127_516274_2 Iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001707 221.0
PYH1_k127_516274_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000005136 160.0
PYH1_k127_5206006_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 531.0
PYH1_k127_5206006_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
PYH1_k127_5228337_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 521.0
PYH1_k127_5228337_1 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 360.0
PYH1_k127_5265537_0 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 2.562e-219 694.0
PYH1_k127_5265537_1 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 336.0
PYH1_k127_5268721_0 GGDEF domain - - - 9.169e-208 661.0
PYH1_k127_5300627_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 9.617e-249 773.0
PYH1_k127_5300627_1 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 427.0
PYH1_k127_5300627_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 331.0
PYH1_k127_5300627_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000005773 214.0
PYH1_k127_5300627_4 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000001041 185.0
PYH1_k127_533563_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.145e-270 845.0
PYH1_k127_533563_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.411e-207 662.0
PYH1_k127_533563_2 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
PYH1_k127_533563_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000002324 128.0
PYH1_k127_533563_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000002113 124.0
PYH1_k127_5358964_0 (GGDEF) domain K21024 - 3.1.4.52 1.369e-197 651.0
PYH1_k127_5358964_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 384.0
PYH1_k127_5358964_2 Rhodanese Homology Domain - - - 0.000000000000000000000002257 102.0
PYH1_k127_5368963_0 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
PYH1_k127_5368963_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000003011 220.0
PYH1_k127_5368963_2 GDSL-like Lipase/Acylhydrolase - - - 0.000001662 61.0
PYH1_k127_5369224_0 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
PYH1_k127_5369224_1 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 262.0
PYH1_k127_5369224_2 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000001629 194.0
PYH1_k127_5401174_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1709.0
PYH1_k127_5401174_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
PYH1_k127_5401174_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 450.0
PYH1_k127_5401174_3 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000005574 226.0
PYH1_k127_5401174_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001362 212.0
PYH1_k127_5401174_5 cystathionine K01739 - 2.5.1.48 0.0000000000000000004961 87.0
PYH1_k127_5462127_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 576.0
PYH1_k127_5462127_1 - - - - 0.0000000000000000000000000000000004636 138.0
PYH1_k127_5463022_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 571.0
PYH1_k127_5463022_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
PYH1_k127_5463022_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 395.0
PYH1_k127_5463022_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
PYH1_k127_5463022_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 323.0
PYH1_k127_5463022_5 type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH1_k127_5463022_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000003111 207.0
PYH1_k127_5465116_0 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 305.0
PYH1_k127_5465116_1 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000001965 175.0
PYH1_k127_5471781_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000004157 211.0
PYH1_k127_5471781_1 transposase activity - - - 0.000000000000000000000000000000000000000512 153.0
PYH1_k127_5471781_2 required for the transposition of insertion element IS2404 - - - 0.000000000000000000000000000000001439 136.0
PYH1_k127_5475396_0 serine threonine protein kinase K12132 - 2.7.11.1 9.392e-312 976.0
PYH1_k127_5475396_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 360.0
PYH1_k127_5475396_2 (FHA) domain - - - 0.00000000000000000000000000000000000000000000002439 171.0
PYH1_k127_5484282_0 Multicopper oxidase K22349 - 1.16.3.3 1.697e-290 907.0
PYH1_k127_5515479_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 493.0
PYH1_k127_5515479_1 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000002047 270.0
PYH1_k127_5515479_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000001164 176.0
PYH1_k127_5537867_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 367.0
PYH1_k127_5537867_1 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 319.0
PYH1_k127_5550531_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.366e-230 716.0
PYH1_k127_5550531_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000002065 94.0
PYH1_k127_5550531_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000008438 61.0
PYH1_k127_5550877_0 type II secretion system protein K02454 - - 1.947e-243 763.0
PYH1_k127_5550877_1 domain, Protein K15923 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 454.0
PYH1_k127_5550877_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 357.0
PYH1_k127_5564006_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.048e-264 826.0
PYH1_k127_5618606_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 509.0
PYH1_k127_5618606_1 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 382.0
PYH1_k127_5618606_2 FR47-like protein - - - 0.0000000000000000000000001584 109.0
PYH1_k127_5619593_0 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 504.0
PYH1_k127_5619593_1 zinc protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 383.0
PYH1_k127_5619593_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002255 225.0
PYH1_k127_5639770_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000353 258.0
PYH1_k127_5639770_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005477 267.0
PYH1_k127_5639770_2 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000001836 135.0
PYH1_k127_5639770_3 Heavy metal-associated domain protein K07213 - - 0.00000000000000000001244 93.0
PYH1_k127_5641826_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1382.0
PYH1_k127_5641826_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.115e-232 728.0
PYH1_k127_5641826_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.685e-207 651.0
PYH1_k127_5641826_3 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 442.0
PYH1_k127_5641826_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000003112 128.0
PYH1_k127_5641826_5 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000005172 77.0
PYH1_k127_5649482_0 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 611.0
PYH1_k127_5649482_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
PYH1_k127_5649482_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002887 276.0
PYH1_k127_5649482_3 - - - - 0.00000000000000000000000000000217 136.0
PYH1_k127_5649482_4 Universal stress protein family - - - 0.00000000000000000000003038 104.0
PYH1_k127_565411_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1438.0
PYH1_k127_565411_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 7.84e-198 646.0
PYH1_k127_5697962_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.759e-227 712.0
PYH1_k127_5697962_1 Chaperone protein TorD - - - 0.0000000000000000000000000000000000000003229 153.0
PYH1_k127_5726916_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 9.192e-312 970.0
PYH1_k127_5726916_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 7.739e-195 618.0
PYH1_k127_5726916_2 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 453.0
PYH1_k127_5726916_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 411.0
PYH1_k127_5726916_4 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 402.0
PYH1_k127_5726916_5 blue (type 1) copper - - - 0.00000000000000000001328 93.0
PYH1_k127_5741169_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
PYH1_k127_5741169_1 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 299.0
PYH1_k127_5741169_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000008177 108.0
PYH1_k127_5741169_3 PFAM EAL domain - - - 0.00006845 52.0
PYH1_k127_5742072_0 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 429.0
PYH1_k127_5742072_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003038 259.0
PYH1_k127_5742072_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001209 261.0
PYH1_k127_5742072_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000000000001701 154.0
PYH1_k127_5742072_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000009096 123.0
PYH1_k127_575002_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.357e-251 783.0
PYH1_k127_575002_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 2.244e-233 727.0
PYH1_k127_575002_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
PYH1_k127_575002_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 497.0
PYH1_k127_575002_4 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 347.0
PYH1_k127_575002_5 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000008138 171.0
PYH1_k127_575002_6 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000004249 162.0
PYH1_k127_5755571_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1420.0
PYH1_k127_5801987_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 456.0
PYH1_k127_5801987_1 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 324.0
PYH1_k127_5801987_2 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000006058 165.0
PYH1_k127_5801987_3 - - - - 0.0000000000000000000000000000000000000007986 154.0
PYH1_k127_5838956_0 ABC transporter transmembrane region K06147 - - 2.927e-303 938.0
PYH1_k127_5838956_1 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 606.0
PYH1_k127_5838956_2 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 345.0
PYH1_k127_5838956_3 Methyltransferase K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 352.0
PYH1_k127_5838956_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
PYH1_k127_5838956_5 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 307.0
PYH1_k127_5838956_6 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00002798 48.0
PYH1_k127_5846776_0 Response regulator receiver K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 598.0
PYH1_k127_5846776_1 PFAM Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 536.0
PYH1_k127_5846776_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002447 106.0
PYH1_k127_5846776_3 Sel1-like repeats. K07126 - - 0.000000000000001363 86.0
PYH1_k127_5852470_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 472.0
PYH1_k127_5852470_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 448.0
PYH1_k127_5852470_10 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000008739 86.0
PYH1_k127_5852470_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 343.0
PYH1_k127_5852470_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH1_k127_5852470_4 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
PYH1_k127_5852470_5 - - - - 0.000000000000000000000000000000000000000000000003008 182.0
PYH1_k127_5852470_6 regulation of methylation-dependent chromatin silencing K03684,K09968 - 3.1.13.5 0.0000000000000000000000000000000000000001795 154.0
PYH1_k127_5852470_7 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000305 138.0
PYH1_k127_5852470_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000008057 134.0
PYH1_k127_5858694_0 Transcriptional regulator, Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
PYH1_k127_5858694_1 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000002429 249.0
PYH1_k127_5858694_2 His Kinase A (phosphoacceptor) domain - - - 0.000002408 53.0
PYH1_k127_5859093_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 310.0
PYH1_k127_5870424_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 9.642e-274 854.0
PYH1_k127_5870424_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 604.0
PYH1_k127_5870424_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 475.0
PYH1_k127_5870424_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
PYH1_k127_5870424_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
PYH1_k127_5870424_5 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000006199 135.0
PYH1_k127_5870424_6 Thioredoxin K05838 - - 0.0000000000000000003021 89.0
PYH1_k127_5884650_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.46e-271 848.0
PYH1_k127_5884650_1 - - - - 0.000000000000000000000002052 112.0
PYH1_k127_5895105_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.107e-301 928.0
PYH1_k127_5895105_1 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.458e-219 687.0
PYH1_k127_5895105_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 576.0
PYH1_k127_5895105_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 362.0
PYH1_k127_5895105_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
PYH1_k127_5895105_5 4Fe-4S dicluster domain K18930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 319.0
PYH1_k127_5895105_6 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000003824 130.0
PYH1_k127_59129_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1065.0
PYH1_k127_59129_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.449e-235 733.0
PYH1_k127_59129_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000002177 70.0
PYH1_k127_59129_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000108 65.0
PYH1_k127_5920_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.437e-208 653.0
PYH1_k127_5920_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 497.0
PYH1_k127_5920_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
PYH1_k127_5920_3 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 387.0
PYH1_k127_5920_4 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000000000000000000001536 174.0
PYH1_k127_5920_5 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000005523 111.0
PYH1_k127_5920_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001086 57.0
PYH1_k127_5922089_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.634e-261 816.0
PYH1_k127_5922089_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 392.0
PYH1_k127_5922089_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000001516 67.0
PYH1_k127_5922089_4 Subtilase family - - - 0.0001101 52.0
PYH1_k127_5931111_0 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
PYH1_k127_5931111_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
PYH1_k127_5931111_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
PYH1_k127_5931111_3 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000002447 199.0
PYH1_k127_5931111_4 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000005727 186.0
PYH1_k127_5931111_5 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000009941 153.0
PYH1_k127_5931111_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000001428 118.0
PYH1_k127_5931111_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000004797 107.0
PYH1_k127_5957349_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000003327 276.0
PYH1_k127_5957349_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000009143 244.0
PYH1_k127_5957349_2 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000000000000000000000000000000001281 213.0
PYH1_k127_5957349_3 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.0000000000000000000000000000000000000000000000000007504 191.0
PYH1_k127_5957349_4 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000004996 139.0
PYH1_k127_5957349_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000003778 56.0
PYH1_k127_596744_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 434.0
PYH1_k127_596744_1 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
PYH1_k127_596744_2 - - - - 0.0000000000000000000001015 100.0
PYH1_k127_596744_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000002074 91.0
PYH1_k127_5969586_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 296.0
PYH1_k127_5969586_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 269.0
PYH1_k127_5969586_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
PYH1_k127_5969586_3 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000001046 220.0
PYH1_k127_5969586_4 Rubredoxin - - - 0.000000000000000000000000009988 119.0
PYH1_k127_5980677_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 611.0
PYH1_k127_5980677_1 Belongs to the UPF0753 family K09822 - - 0.00000000000000000001209 107.0
PYH1_k127_6012909_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 340.0
PYH1_k127_6012909_1 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000000000489 181.0
PYH1_k127_6012909_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000006663 134.0
PYH1_k127_6012909_3 - - - - 0.00001885 53.0
PYH1_k127_6023391_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
PYH1_k127_6023391_1 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
PYH1_k127_6023391_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
PYH1_k127_6110620_0 Belongs to the GPI family K01810 - 5.3.1.9 2.04e-266 828.0
PYH1_k127_6110620_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 445.0
PYH1_k127_6110620_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000002585 143.0
PYH1_k127_6110620_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000009169 92.0
PYH1_k127_6165930_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1704.0
PYH1_k127_6165930_1 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 509.0
PYH1_k127_6165930_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 371.0
PYH1_k127_6165930_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 348.0
PYH1_k127_6165930_4 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
PYH1_k127_6165930_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006193 182.0
PYH1_k127_6165930_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000000000000000000000000000000000006372 173.0
PYH1_k127_6165930_7 - - - - 0.0000000000000000000000000000000000000000003758 177.0
PYH1_k127_6193450_0 Signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
PYH1_k127_6193450_1 PFAM response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000000000005179 230.0
PYH1_k127_6193450_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000006173 111.0
PYH1_k127_6197904_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 558.0
PYH1_k127_6197904_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000006491 170.0
PYH1_k127_6197904_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000001403 136.0
PYH1_k127_6197904_3 PFAM Patatin K07001 - - 0.000000000145 64.0
PYH1_k127_6213524_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 395.0
PYH1_k127_6213524_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000008761 235.0
PYH1_k127_6213524_2 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000001613 207.0
PYH1_k127_6213524_3 protein conserved in bacteria K09806 - - 0.000000000000000000000002086 105.0
PYH1_k127_6220322_0 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 384.0
PYH1_k127_6220322_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007803 269.0
PYH1_k127_6220322_2 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
PYH1_k127_6260203_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.152e-251 786.0
PYH1_k127_6268868_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.574e-271 852.0
PYH1_k127_6268868_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 3.022e-217 679.0
PYH1_k127_6268868_2 III protein, CoA-transferase family K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 422.0
PYH1_k127_6268868_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
PYH1_k127_6268868_4 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000001152 164.0
PYH1_k127_6268868_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000009457 127.0
PYH1_k127_6268868_6 toxin-antitoxin pair type II binding - - - 0.0000000000000008445 79.0
PYH1_k127_6268868_7 - - - - 0.0002172 51.0
PYH1_k127_6288067_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 461.0
PYH1_k127_6288067_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004977 291.0
PYH1_k127_6288067_2 ATP-grasp domain - - - 0.00000001249 57.0
PYH1_k127_6307297_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 407.0
PYH1_k127_6307297_1 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 353.0
PYH1_k127_6307473_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.06e-223 702.0
PYH1_k127_6307473_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00004487 45.0
PYH1_k127_6322660_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 538.0
PYH1_k127_6350576_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 531.0
PYH1_k127_6350576_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 334.0
PYH1_k127_6370400_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 5.867e-230 719.0
PYH1_k127_6370400_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
PYH1_k127_6370400_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000008298 87.0
PYH1_k127_6384909_0 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 463.0
PYH1_k127_6384909_1 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000001147 161.0
PYH1_k127_6384909_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000005991 84.0
PYH1_k127_638739_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 610.0
PYH1_k127_638739_1 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000002934 174.0
PYH1_k127_638739_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000325 153.0
PYH1_k127_6392994_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
PYH1_k127_6392994_1 - - - - 0.0000000000000000000000000000000004333 149.0
PYH1_k127_6393400_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001496 297.0
PYH1_k127_6393400_1 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000001322 258.0
PYH1_k127_6393400_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000003548 233.0
PYH1_k127_6397498_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
PYH1_k127_6397498_1 Glycosyl transferase family 41 - - - 0.000000000000000002148 90.0
PYH1_k127_6397498_2 COGs COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000006812 72.0
PYH1_k127_6408008_0 Ammonium Transporter K03320 - - 2.698e-219 687.0
PYH1_k127_6408008_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 1.278e-216 679.0
PYH1_k127_6408008_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 434.0
PYH1_k127_6408008_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 427.0
PYH1_k127_6408008_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000003955 109.0
PYH1_k127_6461834_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 386.0
PYH1_k127_6461834_1 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
PYH1_k127_6461834_2 - - - - 0.000000000000000000000001386 106.0
PYH1_k127_6461834_3 - - - - 0.00000000000000000001957 102.0
PYH1_k127_6475396_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1165.0
PYH1_k127_6475396_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.042e-211 665.0
PYH1_k127_6475396_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 608.0
PYH1_k127_6475396_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 575.0
PYH1_k127_6475396_4 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 550.0
PYH1_k127_6475396_5 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002683 231.0
PYH1_k127_647722_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1064.0
PYH1_k127_6488184_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 472.0
PYH1_k127_6488184_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
PYH1_k127_6488184_2 Protein of unknown function DUF72 - - - 0.00000000006247 66.0
PYH1_k127_6496798_0 UvrD REP K03657 - 3.6.4.12 0.0 1011.0
PYH1_k127_6496798_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.662e-198 623.0
PYH1_k127_6496798_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 480.0
PYH1_k127_6496798_3 - - - - 0.00000000000000001129 88.0
PYH1_k127_6513217_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 7.078e-207 650.0
PYH1_k127_6513217_1 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000005325 226.0
PYH1_k127_6513217_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
PYH1_k127_6513217_3 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
PYH1_k127_6513217_4 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000001222 100.0
PYH1_k127_6513217_5 - - - - 0.0000000000001994 72.0
PYH1_k127_6513217_7 COG NOG14600 non supervised orthologous group - - - 0.0004132 44.0
PYH1_k127_6522544_0 chain 5 L K00341 - 1.6.5.3 9.971e-300 933.0
PYH1_k127_6522544_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000003088 171.0
PYH1_k127_6522544_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000002607 108.0
PYH1_k127_6524971_0 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000054 259.0
PYH1_k127_6524971_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000007206 227.0
PYH1_k127_6524971_2 YCII-related domain K09780 - - 0.0000000000000000000000000000000001229 144.0
PYH1_k127_6541995_0 24 kD subunit K00122 - 1.17.1.9 1.448e-245 767.0
PYH1_k127_6541995_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000173 199.0
PYH1_k127_655538_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 479.0
PYH1_k127_655538_1 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000001644 167.0
PYH1_k127_655538_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000003357 132.0
PYH1_k127_655737_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 4.412e-194 611.0
PYH1_k127_655737_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 446.0
PYH1_k127_655737_2 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000003516 145.0
PYH1_k127_6580951_0 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 419.0
PYH1_k127_6580951_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000003555 151.0
PYH1_k127_6612353_0 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 541.0
PYH1_k127_6612353_1 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 421.0
PYH1_k127_6612353_2 heat shock protein binding K03686 - - 0.000000001225 62.0
PYH1_k127_6636316_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 437.0
PYH1_k127_6636316_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 281.0
PYH1_k127_6636316_2 response to hydrogen peroxide K08985 - - 0.0000001592 61.0
PYH1_k127_6647857_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 312.0
PYH1_k127_6647857_1 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000000000000000000000001184 247.0
PYH1_k127_6647857_2 nitrogen regulatory protein P-II - - - 0.00000000000005562 72.0
PYH1_k127_6647857_3 haloacid dehalogenase K01560 - 3.8.1.2 0.0006524 42.0
PYH1_k127_6647858_0 Beta-Casp domain K07576 - - 1.71e-196 627.0
PYH1_k127_6647858_1 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 573.0
PYH1_k127_6647858_2 membrane - - - 0.0000000000000000000000000000000000000000008664 162.0
PYH1_k127_6647858_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000002582 125.0
PYH1_k127_6647858_4 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000003372 128.0
PYH1_k127_6667405_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 8.517e-254 793.0
PYH1_k127_6682931_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
PYH1_k127_6682931_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
PYH1_k127_6682931_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000007697 221.0
PYH1_k127_6682931_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000007072 171.0
PYH1_k127_6682931_4 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000002155 132.0
PYH1_k127_6695795_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.815e-266 828.0
PYH1_k127_6745908_0 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 428.0
PYH1_k127_6745908_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000007883 235.0
PYH1_k127_674722_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 504.0
PYH1_k127_674722_1 - - - - 0.0000000000004594 71.0
PYH1_k127_6750547_0 acyl-CoA dehydrogenase K06445 - - 6.697e-238 747.0
PYH1_k127_6771287_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.66e-236 740.0
PYH1_k127_6771287_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 518.0
PYH1_k127_6771287_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 373.0
PYH1_k127_6771287_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000001832 107.0
PYH1_k127_6771617_0 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000005137 229.0
PYH1_k127_6771617_1 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000001118 180.0
PYH1_k127_6771617_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000277 106.0
PYH1_k127_6771617_3 KR domain - - - 0.000001906 59.0
PYH1_k127_677225_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.523e-217 683.0
PYH1_k127_677225_2 PFAM Cytochrome c assembly protein - - - 0.0001133 44.0
PYH1_k127_680399_0 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 334.0
PYH1_k127_680399_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
PYH1_k127_680399_2 TIGRFAM DnaA regulatory inactivator Hda K10763 - - 0.00000000000000000000000000007115 117.0
PYH1_k127_682337_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 468.0
PYH1_k127_6844734_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.483e-261 812.0
PYH1_k127_6844734_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 409.0
PYH1_k127_6844734_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
PYH1_k127_6844734_3 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000442 127.0
PYH1_k127_6844734_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000002041 78.0
PYH1_k127_6856867_0 Poly-beta-hydroxybutyrate K03821 - - 6.723e-212 673.0
PYH1_k127_6856867_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.66e-211 665.0
PYH1_k127_6856867_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000004317 61.0
PYH1_k127_6856867_2 TrkA-N domain protein K03499 - - 7.984e-205 647.0
PYH1_k127_6856867_3 chemotaxis K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 497.0
PYH1_k127_6856867_4 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 354.0
PYH1_k127_6856867_5 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
PYH1_k127_6856867_6 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
PYH1_k127_6856867_7 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002247 198.0
PYH1_k127_6856867_8 PFAM CheW domain protein K02659 - - 0.000000000000000000000000000000000000000000004014 171.0
PYH1_k127_6856867_9 Histidine kinase K02487,K06596 - - 0.00000000000000000000429 97.0
PYH1_k127_6859992_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1287.0
PYH1_k127_6859992_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 608.0
PYH1_k127_6859992_10 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000001261 150.0
PYH1_k127_6859992_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000008933 132.0
PYH1_k127_6859992_12 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000003374 79.0
PYH1_k127_6859992_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 582.0
PYH1_k127_6859992_3 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 578.0
PYH1_k127_6859992_4 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 544.0
PYH1_k127_6859992_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 523.0
PYH1_k127_6859992_6 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 465.0
PYH1_k127_6859992_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 346.0
PYH1_k127_6859992_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 334.0
PYH1_k127_6859992_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000005387 178.0
PYH1_k127_6861739_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000004791 198.0
PYH1_k127_6861739_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001733 187.0
PYH1_k127_6861739_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000002196 99.0
PYH1_k127_6912830_0 PQQ-like domain - - - 0.0 1106.0
PYH1_k127_6912830_1 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 450.0
PYH1_k127_6912830_2 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 382.0
PYH1_k127_6912830_3 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
PYH1_k127_6912830_4 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004521 250.0
PYH1_k127_6912830_5 Pterin 4 alpha carbinolamine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000002629 219.0
PYH1_k127_6912830_6 - - - - 0.0000000000000000000000000000000000000000000000000000008787 203.0
PYH1_k127_6912830_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000002771 154.0
PYH1_k127_6912830_8 Cytochrome c - - - 0.00000000000000000000000000003808 132.0
PYH1_k127_6944690_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2050.0
PYH1_k127_6944690_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1922.0
PYH1_k127_6944690_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000002761 117.0
PYH1_k127_694609_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000164 126.0
PYH1_k127_694609_1 - - - - 0.000000000000000000002325 100.0
PYH1_k127_694609_2 Site-specific recombinase - - - 0.00000000000000000004343 104.0
PYH1_k127_694609_3 - - - - 0.00006775 53.0
PYH1_k127_6964090_0 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 608.0
PYH1_k127_6964090_1 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000000000001192 189.0
PYH1_k127_6978726_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 571.0
PYH1_k127_6978726_1 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 524.0
PYH1_k127_6978726_2 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 396.0
PYH1_k127_6978726_3 integral membrane protein - - - 0.0000000000000000000002388 97.0
PYH1_k127_6978726_5 Predicted integral membrane protein (DUF2269) - - - 0.00000000004248 67.0
PYH1_k127_6978726_6 - - - - 0.0000000009836 61.0
PYH1_k127_6978726_8 integral membrane protein - - - 0.00002196 47.0
PYH1_k127_6983630_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1334.0
PYH1_k127_6988002_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 527.0
PYH1_k127_6999280_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000769 110.0
PYH1_k127_6999280_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000008579 58.0
PYH1_k127_7003391_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.436e-251 781.0
PYH1_k127_7003391_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 1.501e-209 657.0
PYH1_k127_7003391_2 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
PYH1_k127_7003391_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000004044 61.0
PYH1_k127_7014673_0 Magnesium transport protein CorA - - - 3.854e-229 721.0
PYH1_k127_7014673_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 402.0
PYH1_k127_7014673_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000004321 170.0
PYH1_k127_7035207_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 340.0
PYH1_k127_7035207_1 Sulphur oxidation protein SoxZ K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 348.0
PYH1_k127_7050227_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
PYH1_k127_7050227_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000005761 176.0
PYH1_k127_7050227_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000002033 160.0
PYH1_k127_7050227_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000003812 141.0
PYH1_k127_7050227_4 - - - - 0.000003874 53.0
PYH1_k127_7096541_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 506.0
PYH1_k127_7096541_1 - - - - 0.000000000000000000000000000000000000000000000000000000000007061 231.0
PYH1_k127_7102717_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 449.0
PYH1_k127_7102717_1 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000005974 160.0
PYH1_k127_7102717_2 Prokaryotic N-terminal methylation motif - - - 0.0000005826 51.0
PYH1_k127_7107858_0 Pfam Fatty acid - - - 0.0 1069.0
PYH1_k127_7107858_1 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 433.0
PYH1_k127_7107858_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 422.0
PYH1_k127_7107858_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 362.0
PYH1_k127_7107858_4 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 327.0
PYH1_k127_7107858_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000003154 208.0
PYH1_k127_7107858_6 - - - - 0.000000000000000000000000000000000001264 150.0
PYH1_k127_7107858_7 Na -dependent transporter K03453 - - 0.00000000005973 70.0
PYH1_k127_7107858_8 DNA repair photolyase - - - 0.00004098 46.0
PYH1_k127_7126345_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 7.081e-208 679.0
PYH1_k127_7126345_1 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 368.0
PYH1_k127_7126345_2 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
PYH1_k127_7126345_3 - - - - 0.00000000000000000000009504 108.0
PYH1_k127_7132395_0 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 313.0
PYH1_k127_7132395_1 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000007831 246.0
PYH1_k127_7132395_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000001626 137.0
PYH1_k127_7161164_0 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 597.0
PYH1_k127_7161164_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
PYH1_k127_7161164_10 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000007515 247.0
PYH1_k127_7161164_11 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000001189 158.0
PYH1_k127_7161164_12 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000001162 115.0
PYH1_k127_7161164_13 ThiS family K03154 - - 0.000000000000000000002249 95.0
PYH1_k127_7161164_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 541.0
PYH1_k127_7161164_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 445.0
PYH1_k127_7161164_4 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 424.0
PYH1_k127_7161164_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 365.0
PYH1_k127_7161164_6 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 335.0
PYH1_k127_7161164_7 Formaldehyde-activating enzyme (Fae) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 304.0
PYH1_k127_7161164_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 293.0
PYH1_k127_7161164_9 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 270.0
PYH1_k127_7205367_0 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
PYH1_k127_7205367_1 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 260.0
PYH1_k127_7205367_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
PYH1_k127_7215704_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 581.0
PYH1_k127_7215704_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 356.0
PYH1_k127_7215704_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
PYH1_k127_7215704_3 Protein of unknown function DUF45 K07043 - - 0.0000007198 61.0
PYH1_k127_7227986_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 9.927e-209 655.0
PYH1_k127_7227986_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 535.0
PYH1_k127_7255652_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 425.0
PYH1_k127_7255652_1 Belongs to the UPF0337 (CsbD) family - - - 0.000000776 55.0
PYH1_k127_7274695_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 8.285e-224 701.0
PYH1_k127_7274695_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
PYH1_k127_7274695_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
PYH1_k127_7275755_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1007.0
PYH1_k127_7275755_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.448e-281 871.0
PYH1_k127_7275755_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 561.0
PYH1_k127_7275755_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 382.0
PYH1_k127_7275755_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
PYH1_k127_7275755_5 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002873 265.0
PYH1_k127_7275755_6 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000277 276.0
PYH1_k127_7275755_7 Protein of unknown function (DUF2905) - - - 0.000000000000000000000099 99.0
PYH1_k127_7285707_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.44e-229 716.0
PYH1_k127_7285707_1 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 7.762e-203 650.0
PYH1_k127_7285707_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 426.0
PYH1_k127_7285707_3 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
PYH1_k127_7285707_4 Phasin protein - - - 0.00000000000000000000000000000000000000003474 159.0
PYH1_k127_7285707_5 - - - - 0.0001697 46.0
PYH1_k127_7312660_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 5.818e-248 772.0
PYH1_k127_7312660_1 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
PYH1_k127_7321528_0 Acyl-CoA dehydrogenase N terminal K20035 - - 1.069e-258 809.0
PYH1_k127_7321528_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 431.0
PYH1_k127_7321528_2 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
PYH1_k127_7321528_3 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 393.0
PYH1_k127_7321528_4 acyl-CoA dehydrogenase K06445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001808 265.0
PYH1_k127_7321528_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
PYH1_k127_7330704_0 Nitronate monooxygenase K00459 - 1.13.12.16 6.932e-224 701.0
PYH1_k127_7330704_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 560.0
PYH1_k127_7330704_2 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
PYH1_k127_7330704_3 - - - - 0.0000000002743 66.0
PYH1_k127_7330704_4 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0006269 47.0
PYH1_k127_7386923_0 SMART Elongator protein 3 MiaB NifB K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 493.0
PYH1_k127_7386923_1 lipoate-protein ligase A K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 475.0
PYH1_k127_7386923_2 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 322.0
PYH1_k127_7386923_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
PYH1_k127_7386923_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000004977 211.0
PYH1_k127_7386923_5 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000002649 179.0
PYH1_k127_7386923_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000007935 138.0
PYH1_k127_7386923_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000002589 117.0
PYH1_k127_7386923_8 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000001237 80.0
PYH1_k127_7392992_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 5.596e-224 710.0
PYH1_k127_7401765_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
PYH1_k127_7401765_1 Alpha beta hydrolase - - - 0.00000000000000005406 82.0
PYH1_k127_7450429_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.782e-250 778.0
PYH1_k127_7450429_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.094e-218 685.0
PYH1_k127_7450429_10 membrane K06077 - - 0.00000000000000001258 86.0
PYH1_k127_7450429_2 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 564.0
PYH1_k127_7450429_3 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
PYH1_k127_7450429_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 304.0
PYH1_k127_7450429_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
PYH1_k127_7450429_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000005051 192.0
PYH1_k127_7450429_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000002016 177.0
PYH1_k127_7450429_8 HNH nucleases - - - 0.00000000000000000000000000000000000000000000001097 177.0
PYH1_k127_7450429_9 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000002018 85.0
PYH1_k127_7462094_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.407e-265 832.0
PYH1_k127_7462094_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
PYH1_k127_7462094_2 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000001257 115.0
PYH1_k127_7462094_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000008778 98.0
PYH1_k127_7478425_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.994e-228 711.0
PYH1_k127_7478425_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.11e-217 686.0
PYH1_k127_7478425_2 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 238.0
PYH1_k127_7491051_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 498.0
PYH1_k127_7491051_1 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 352.0
PYH1_k127_7511785_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 462.0
PYH1_k127_7511785_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
PYH1_k127_7511785_2 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000001234 195.0
PYH1_k127_7511785_3 Protein of unknown function (DUF3568) - - - 0.0000000000000000000000001193 111.0
PYH1_k127_7512762_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1069.0
PYH1_k127_7512762_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 302.0
PYH1_k127_7512762_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000718 69.0
PYH1_k127_7512762_2 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008862 275.0
PYH1_k127_7512762_3 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000004183 182.0
PYH1_k127_7512762_4 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000004284 175.0
PYH1_k127_7512762_5 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000001109 143.0
PYH1_k127_7512762_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000004627 139.0
PYH1_k127_7512762_7 CBS domain - - - 0.0000000000000000000000000000001708 135.0
PYH1_k127_7512762_8 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000000001849 126.0
PYH1_k127_7512762_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005082 113.0
PYH1_k127_7513251_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 550.0
PYH1_k127_7513251_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 371.0
PYH1_k127_7513251_2 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000002293 167.0
PYH1_k127_7513251_3 response regulator - - - 0.0000000000000000001348 94.0
PYH1_k127_7538487_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.531e-208 659.0
PYH1_k127_7538487_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 611.0
PYH1_k127_7538487_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 355.0
PYH1_k127_7538487_3 AMMECR1 - - - 0.000000000000000000000000000000000000000000000000000000000000000005606 233.0
PYH1_k127_7538487_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000001588 162.0
PYH1_k127_7555775_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 458.0
PYH1_k127_7555775_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000004212 242.0
PYH1_k127_7564364_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 364.0
PYH1_k127_7564364_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
PYH1_k127_7564364_2 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000005964 213.0
PYH1_k127_7564364_3 metallophosphoesterase - - - 0.00000000001281 66.0
PYH1_k127_757183_0 ABC transporter K15738 - - 8.331e-212 666.0
PYH1_k127_757183_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
PYH1_k127_757183_2 Bile acid K03453 - - 0.0000001391 55.0
PYH1_k127_7593154_0 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 411.0
PYH1_k127_7593154_1 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000004957 168.0
PYH1_k127_7593154_2 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396,K17950 - 4.4.1.15,4.4.1.25 0.0000000000000000000000000000421 118.0
PYH1_k127_7593154_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.0000000000000000000000001544 106.0
PYH1_k127_7598642_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 303.0
PYH1_k127_7598642_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 300.0
PYH1_k127_7598642_2 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000001893 174.0
PYH1_k127_7610243_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 434.0
PYH1_k127_7610243_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000286 203.0
PYH1_k127_7611853_0 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 410.0
PYH1_k127_7611853_1 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 312.0
PYH1_k127_7611853_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000003283 250.0
PYH1_k127_7611853_3 Major Facilitator Superfamily - - - 0.00000000000000000009444 90.0
PYH1_k127_7622313_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
PYH1_k127_7622313_1 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 351.0
PYH1_k127_7622313_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 311.0
PYH1_k127_7622313_3 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000619 183.0
PYH1_k127_7622313_4 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000008066 156.0
PYH1_k127_7633057_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.974e-211 665.0
PYH1_k127_7633057_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 374.0
PYH1_k127_7633057_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 333.0
PYH1_k127_7633057_3 esterase, PHB depolymerase - - - 0.0000000000000000000000000000000000000000001457 177.0
PYH1_k127_7650283_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.16e-235 747.0
PYH1_k127_7650283_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000291 244.0
PYH1_k127_7650283_2 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000003335 57.0
PYH1_k127_7658541_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 5.723e-218 708.0
PYH1_k127_7658541_1 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 488.0
PYH1_k127_7658541_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000133 91.0
PYH1_k127_7659697_0 Competence protein ComEC Rec2 K02238 - - 8.074e-223 703.0
PYH1_k127_7661233_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1054.0
PYH1_k127_7661233_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000003161 173.0
PYH1_k127_766443_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.63e-237 741.0
PYH1_k127_766443_1 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 409.0
PYH1_k127_766443_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
PYH1_k127_766443_3 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000006979 199.0
PYH1_k127_766443_4 RDD family - - - 0.000000000000000000000000001201 114.0
PYH1_k127_7666528_0 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 502.0
PYH1_k127_7666528_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 485.0
PYH1_k127_7666528_2 DNA mismatch repair protein, C-terminal domain K03572 - - 0.0000000000000000000000000000000000000000000001808 169.0
PYH1_k127_7666528_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000002224 145.0
PYH1_k127_7669903_0 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000002788 249.0
PYH1_k127_7669903_1 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000001371 208.0
PYH1_k127_7669903_2 PFAM molydopterin dinucleotide-binding region K00203,K00336 - 1.2.7.12,1.6.5.3 0.00000000000000003861 85.0
PYH1_k127_7680206_0 His Kinase A (phosphoacceptor) domain K11711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 383.0
PYH1_k127_7680206_1 response regulator K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
PYH1_k127_7680206_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000002312 119.0
PYH1_k127_7691117_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 7.57e-280 867.0
PYH1_k127_7691117_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000003939 258.0
PYH1_k127_7691117_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
PYH1_k127_7691117_3 - - - - 0.000000000000000000000000006593 111.0
PYH1_k127_7693292_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.685e-250 782.0
PYH1_k127_7693292_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 352.0
PYH1_k127_7693292_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 322.0
PYH1_k127_7694281_0 AMP-binding enzyme C-terminal domain K00666 - - 2.623e-282 874.0
PYH1_k127_7694281_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.633e-226 707.0
PYH1_k127_7694281_2 ABC transporter K01999 - - 1.69e-198 625.0
PYH1_k127_7694281_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 493.0
PYH1_k127_7694281_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
PYH1_k127_7694281_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 380.0
PYH1_k127_7694281_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 286.0
PYH1_k127_7694281_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000005313 188.0
PYH1_k127_7694281_8 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000006571 188.0
PYH1_k127_7694281_9 - - - - 0.000000000000000007393 100.0
PYH1_k127_770041_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
PYH1_k127_770041_1 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000002703 132.0
PYH1_k127_770041_2 PFAM TOBE domain protein - - - 0.000000000000000001779 87.0
PYH1_k127_7704402_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 6.723e-249 774.0
PYH1_k127_7704402_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 347.0
PYH1_k127_7704402_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000009575 153.0
PYH1_k127_7714160_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 343.0
PYH1_k127_7714160_1 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000008335 125.0
PYH1_k127_7721124_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 308.0
PYH1_k127_7721124_1 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003606 181.0
PYH1_k127_7721124_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000008467 94.0
PYH1_k127_7721124_3 transcriptional regulator - - - 0.00000000000009991 72.0
PYH1_k127_7738510_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1009.0
PYH1_k127_7738510_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 396.0
PYH1_k127_7738510_2 - - - - 0.0000000000000000000000000000000003959 140.0
PYH1_k127_7744702_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 482.0
PYH1_k127_7744702_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
PYH1_k127_7744702_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
PYH1_k127_7744702_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000001654 71.0
PYH1_k127_7757047_0 Transmembrane secretion effector - - - 2.364e-243 771.0
PYH1_k127_7757047_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 581.0
PYH1_k127_7757047_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 355.0
PYH1_k127_7757047_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
PYH1_k127_7757047_4 AsmA family K07289,K07290 - - 0.00000000000000000000000000000312 127.0
PYH1_k127_7757047_5 - - - - 0.000001692 56.0
PYH1_k127_7764178_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1035.0
PYH1_k127_7764178_1 TonB-dependent Receptor Plug K02014 - - 3.011e-251 798.0
PYH1_k127_7764178_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 534.0
PYH1_k127_7764178_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 302.0
PYH1_k127_7764178_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
PYH1_k127_7764178_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
PYH1_k127_7764178_6 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000001661 239.0
PYH1_k127_7764178_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000002981 108.0
PYH1_k127_7764178_8 Mut7-C ubiquitin - - - 0.00000000000000000000001721 113.0
PYH1_k127_7764178_9 - - - - 0.0000000000000002644 89.0
PYH1_k127_7771390_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 554.0
PYH1_k127_7771390_1 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 325.0
PYH1_k127_7771390_2 Dolichyl-phosphate-mannose-protein mannosyltransferase K00786 - - 0.0000000000000000000000000000000000000000000000000009515 192.0
PYH1_k127_7771390_3 GtrA-like protein - - - 0.000000000000000000000000178 112.0
PYH1_k127_7771545_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 331.0
PYH1_k127_7771545_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 302.0
PYH1_k127_7771545_2 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000000000000000001148 140.0
PYH1_k127_7771545_3 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000000402 98.0
PYH1_k127_7771545_4 Protein of unknown function DUF99 K09120 - - 0.00001745 50.0
PYH1_k127_7774777_0 PFAM ATPase associated with various cellular activities, AAA_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 480.0
PYH1_k127_7774777_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000003338 133.0
PYH1_k127_7775285_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 389.0
PYH1_k127_7775285_2 import inner membrane translocase subunit Tim44 - - - 0.00002705 47.0
PYH1_k127_7789695_0 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 540.0
PYH1_k127_7789695_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 460.0
PYH1_k127_7789695_2 Type II secretion system protein B K02451 - - 0.000000000000000004677 87.0
PYH1_k127_7792251_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 578.0
PYH1_k127_7792251_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000005005 196.0
PYH1_k127_7792251_2 TolA C-terminal K03646 - - 0.00000000000000000000000000000004403 133.0
PYH1_k127_7792251_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000002024 92.0
PYH1_k127_7815550_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 445.0
PYH1_k127_7815550_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 306.0
PYH1_k127_7815550_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005469 230.0
PYH1_k127_7815550_3 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000001293 127.0
PYH1_k127_7835288_0 Belongs to the malate synthase family K01638 - 2.3.3.9 5.902e-279 867.0
PYH1_k127_7835288_1 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 565.0
PYH1_k127_7835288_2 (ABC) transporter K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
PYH1_k127_7835288_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002703 254.0
PYH1_k127_7835288_4 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
PYH1_k127_7835288_5 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000003481 170.0
PYH1_k127_7841132_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.085e-272 844.0
PYH1_k127_7841132_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 502.0
PYH1_k127_7841132_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 477.0
PYH1_k127_7841132_3 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000002872 171.0
PYH1_k127_7841132_4 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000236 128.0
PYH1_k127_7857915_0 Molecular chaperone. Has ATPase activity K04079 - - 2.53e-288 899.0
PYH1_k127_7857915_1 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 292.0
PYH1_k127_7858167_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0 1184.0
PYH1_k127_7858167_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000002153 195.0
PYH1_k127_7869007_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 3.616e-269 839.0
PYH1_k127_7869007_1 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
PYH1_k127_7883336_0 Outer membrane protein beta-barrel family - - - 1.503e-276 872.0
PYH1_k127_7883336_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000001141 138.0
PYH1_k127_7891184_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 370.0
PYH1_k127_7891184_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000008109 202.0
PYH1_k127_7891184_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000001768 193.0
PYH1_k127_7891184_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000001644 132.0
PYH1_k127_7894697_0 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003664 293.0
PYH1_k127_7894697_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000003272 214.0
PYH1_k127_7896892_0 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 265.0
PYH1_k127_7896892_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
PYH1_k127_7896892_2 Glycine zipper 2TM domain - - - 0.0000551 49.0
PYH1_k127_7898788_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1179.0
PYH1_k127_7903271_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 322.0
PYH1_k127_7903271_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0000000000000000000000000000000103 128.0
PYH1_k127_7903271_2 diguanylate cyclase - - - 0.0000000000000000000000000006668 127.0
PYH1_k127_7903271_3 diguanylate cyclase - - - 0.000003989 49.0
PYH1_k127_7907888_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000006207 237.0
PYH1_k127_7907888_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
PYH1_k127_7907888_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000005483 183.0
PYH1_k127_7907888_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000000000861 66.0
PYH1_k127_7911523_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 571.0
PYH1_k127_7911523_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 538.0
PYH1_k127_791657_0 PFAM multicopper oxidase type 2 K22350 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 582.0
PYH1_k127_791657_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 387.0
PYH1_k127_791657_2 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
PYH1_k127_791657_3 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000003077 136.0
PYH1_k127_7923420_0 Homospermidine synthase K00808 - 2.5.1.44 2.745e-216 684.0
PYH1_k127_7923420_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 314.0
PYH1_k127_7923420_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 271.0
PYH1_k127_7923420_3 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000001547 213.0
PYH1_k127_7923420_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000007422 180.0
PYH1_k127_7923420_5 Protein of unknown function (DUF3567) - - - 0.00000000001197 68.0
PYH1_k127_7933441_0 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 414.0
PYH1_k127_7933441_1 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
PYH1_k127_7933441_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
PYH1_k127_7933441_3 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000001542 139.0
PYH1_k127_7933441_4 - - - - 0.0000007764 55.0
PYH1_k127_7939306_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1116.0
PYH1_k127_7941231_0 ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 557.0
PYH1_k127_7941231_1 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 319.0
PYH1_k127_7941231_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000002599 83.0
PYH1_k127_7944410_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000002455 198.0
PYH1_k127_7944410_1 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000009448 201.0
PYH1_k127_7944410_2 - - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
PYH1_k127_7944410_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000001183 182.0
PYH1_k127_7949214_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
PYH1_k127_7949214_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 406.0
PYH1_k127_7964653_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1140.0
PYH1_k127_7964653_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 419.0
PYH1_k127_7964653_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000003835 165.0
PYH1_k127_7965957_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1244.0
PYH1_k127_7965957_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 549.0
PYH1_k127_7965957_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
PYH1_k127_7965957_3 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 432.0
PYH1_k127_7965957_4 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
PYH1_k127_7965957_5 Molecular chaperone K05516 - - 0.0000000000000000000000000000000000000000001364 161.0
PYH1_k127_7965957_6 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.00000000000000000000000000000007329 129.0
PYH1_k127_7965957_7 MerR HTH family regulatory protein K18997 - - 0.00000000004978 68.0
PYH1_k127_7967059_0 Heat shock 70 kDa protein K04043 - - 2.036e-321 993.0
PYH1_k127_7967059_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 606.0
PYH1_k127_7967059_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000004758 178.0
PYH1_k127_7967059_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000001824 64.0
PYH1_k127_7984348_0 Member of a two-component regulatory system K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 372.0
PYH1_k127_7984348_1 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 317.0
PYH1_k127_7984348_2 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 313.0
PYH1_k127_7984348_3 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
PYH1_k127_7984348_4 - K09004 - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
PYH1_k127_7984348_5 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000001025 144.0
PYH1_k127_7987176_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 593.0
PYH1_k127_7987176_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 506.0
PYH1_k127_7992252_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.05e-208 658.0
PYH1_k127_7995087_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 327.0
PYH1_k127_7995087_1 - - - - 0.000000000000000000000000000000000000000000000000000004542 200.0
PYH1_k127_7995087_2 Cysteine-rich CWC - - - 0.0003881 44.0
PYH1_k127_8013910_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 527.0
PYH1_k127_8013910_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 452.0
PYH1_k127_8013910_10 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000424 110.0
PYH1_k127_8013910_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 443.0
PYH1_k127_8013910_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 323.0
PYH1_k127_8013910_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000006849 262.0
PYH1_k127_8013910_5 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 256.0
PYH1_k127_8013910_6 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
PYH1_k127_8013910_7 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.0000000000000000000000000000000000001355 147.0
PYH1_k127_8013910_8 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000002447 132.0
PYH1_k127_8013910_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000002562 97.0
PYH1_k127_80195_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 523.0
PYH1_k127_80195_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 439.0
PYH1_k127_80195_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 336.0
PYH1_k127_80195_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
PYH1_k127_80195_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000392 203.0
PYH1_k127_80195_5 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000000000000002637 191.0
PYH1_k127_8025166_0 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 329.0
PYH1_k127_8025166_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001108 299.0
PYH1_k127_8025166_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003661 244.0
PYH1_k127_8025166_3 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
PYH1_k127_8026735_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.726e-219 688.0
PYH1_k127_8026735_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
PYH1_k127_8026735_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000007601 89.0
PYH1_k127_8030211_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 317.0
PYH1_k127_8030211_1 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
PYH1_k127_8030211_2 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000001406 191.0
PYH1_k127_8030211_3 NusG domain II - - - 0.0000000000002612 71.0
PYH1_k127_8037262_0 O-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 589.0
PYH1_k127_8037262_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 335.0
PYH1_k127_8042033_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 4.261e-207 663.0
PYH1_k127_8052544_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000006262 190.0
PYH1_k127_8052544_1 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000001832 154.0
PYH1_k127_805718_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 533.0
PYH1_k127_805718_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000002553 211.0
PYH1_k127_805718_2 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis K08906 - - 0.000001141 55.0
PYH1_k127_8074198_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1433.0
PYH1_k127_8074198_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.799e-318 987.0
PYH1_k127_8074198_2 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 402.0
PYH1_k127_8074198_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
PYH1_k127_8074198_4 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 251.0
PYH1_k127_8074198_5 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000009149 131.0
PYH1_k127_8074198_6 Protein of unknown function (DUF2889) - - - 0.000000004419 62.0
PYH1_k127_8075335_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 578.0
PYH1_k127_8075335_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000002013 228.0
PYH1_k127_8075335_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000001219 169.0
PYH1_k127_8075335_3 - - - - 0.000000000000000000000000000000000000000001338 172.0
PYH1_k127_8075335_4 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000008561 132.0
PYH1_k127_8075335_5 Ion channel - - - 0.0000000000000002405 88.0
PYH1_k127_8095562_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1301.0
PYH1_k127_8095562_1 DNA polymerase III K02342 - 2.7.7.7 1.222e-238 757.0
PYH1_k127_8095562_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.21e-205 686.0
PYH1_k127_8095562_3 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002828 280.0
PYH1_k127_8095562_4 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000008179 175.0
PYH1_k127_8095562_5 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000001848 131.0
PYH1_k127_8095562_6 - - - - 0.000000000000001895 78.0
PYH1_k127_8095562_7 Metallo-beta-lactamase superfamily - - - 0.000000000004607 66.0
PYH1_k127_8117156_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1423.0
PYH1_k127_8118720_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.926e-253 801.0
PYH1_k127_8118720_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 464.0
PYH1_k127_8118720_2 2Fe-2S iron-sulfur cluster binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000001184 161.0
PYH1_k127_8118720_3 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000003015 133.0
PYH1_k127_8118720_4 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000007236 118.0
PYH1_k127_8130906_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 559.0
PYH1_k127_8130906_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
PYH1_k127_8130906_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 333.0
PYH1_k127_8131959_0 Tripartite tricarboxylate transporter TctA family K07793 - - 9.052e-257 799.0
PYH1_k127_8131959_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 527.0
PYH1_k127_8131959_2 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
PYH1_k127_8131959_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 379.0
PYH1_k127_8131959_4 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
PYH1_k127_814522_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 297.0
PYH1_k127_814522_1 Polysaccharide biosynthesis protein K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000004604 141.0
PYH1_k127_814522_2 O-Antigen ligase K02847 - - 0.00000000000008699 72.0
PYH1_k127_8152050_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 425.0
PYH1_k127_8152050_1 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007124 237.0
PYH1_k127_8152050_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000538 126.0
PYH1_k127_8155115_0 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 593.0
PYH1_k127_8155115_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
PYH1_k127_8155115_2 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
PYH1_k127_8155115_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000008254 95.0
PYH1_k127_8159352_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 401.0
PYH1_k127_8159352_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 386.0
PYH1_k127_8159352_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
PYH1_k127_8159352_3 ApaG domain - - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
PYH1_k127_816154_0 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000003852 180.0
PYH1_k127_816154_1 - - - - 0.00000000000000000000000000000000000006208 156.0
PYH1_k127_816154_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000001248 115.0
PYH1_k127_8183046_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 518.0
PYH1_k127_8183046_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 532.0
PYH1_k127_8183046_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 357.0
PYH1_k127_8183046_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 338.0
PYH1_k127_8183046_4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
PYH1_k127_8183046_5 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000002477 182.0
PYH1_k127_8184830_0 Polysaccharide biosynthesis protein - - - 1.603e-255 799.0
PYH1_k127_8204325_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
PYH1_k127_8204325_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 350.0
PYH1_k127_8204325_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000002366 254.0
PYH1_k127_8204325_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000001354 203.0
PYH1_k127_8221211_0 PA domain - - - 1.98e-200 637.0
PYH1_k127_8336290_0 Protein of unknown function (DUF3141) - - - 0.0 1032.0
PYH1_k127_8336290_1 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 3.895e-241 759.0
PYH1_k127_8336290_10 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000005469 149.0
PYH1_k127_8336290_11 - - - - 0.00000000000000000000000003099 110.0
PYH1_k127_8336290_12 - - - - 0.00000000000000002774 87.0
PYH1_k127_8336290_13 - - - - 0.0000000028 63.0
PYH1_k127_8336290_14 - - - - 0.000000008634 58.0
PYH1_k127_8336290_15 - - - - 0.00001554 50.0
PYH1_k127_8336290_2 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 603.0
PYH1_k127_8336290_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 572.0
PYH1_k127_8336290_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 547.0
PYH1_k127_8336290_5 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 464.0
PYH1_k127_8336290_6 phosphate K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
PYH1_k127_8336290_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 437.0
PYH1_k127_8336290_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
PYH1_k127_8336290_9 lipid catabolic process - - - 0.0000000000000000000000000000000000000000000005543 184.0
PYH1_k127_858053_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.369e-287 886.0
PYH1_k127_858053_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 411.0
PYH1_k127_858053_2 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.000000000000000000000000000000000000000000000000002023 188.0
PYH1_k127_858053_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000001745 75.0
PYH1_k127_859141_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 613.0
PYH1_k127_859141_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 517.0
PYH1_k127_859141_10 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000006445 104.0
PYH1_k127_859141_11 Protein of unknown function (DUF2788) - - - 0.000000000000000000000006778 102.0
PYH1_k127_859141_12 - - - - 0.0000004668 61.0
PYH1_k127_859141_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 463.0
PYH1_k127_859141_3 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 386.0
PYH1_k127_859141_4 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 397.0
PYH1_k127_859141_5 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
PYH1_k127_859141_6 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 273.0
PYH1_k127_859141_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
PYH1_k127_859141_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000002442 248.0
PYH1_k127_859141_9 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
PYH1_k127_862183_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.324e-269 841.0
PYH1_k127_875389_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 609.0
PYH1_k127_875389_1 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 382.0
PYH1_k127_875389_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003005 235.0
PYH1_k127_875389_3 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000005207 164.0
PYH1_k127_875389_4 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000003336 108.0
PYH1_k127_904225_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.614e-250 784.0
PYH1_k127_904225_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.482e-232 726.0
PYH1_k127_904225_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000002436 134.0
PYH1_k127_904225_11 - - - - 0.000000000000000000000000000000008954 132.0
PYH1_k127_904225_12 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000002042 119.0
PYH1_k127_904225_13 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000005378 79.0
PYH1_k127_904225_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.062e-196 617.0
PYH1_k127_904225_3 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 545.0
PYH1_k127_904225_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 544.0
PYH1_k127_904225_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
PYH1_k127_904225_6 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
PYH1_k127_904225_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 303.0
PYH1_k127_904225_8 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000001033 183.0
PYH1_k127_904225_9 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000003956 136.0
PYH1_k127_915448_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.002e-206 649.0
PYH1_k127_915448_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 517.0
PYH1_k127_915448_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000001014 233.0
PYH1_k127_915448_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000011 142.0
PYH1_k127_915448_4 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000006002 65.0
PYH1_k127_947797_0 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000002047 229.0
PYH1_k127_947797_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000347 211.0
PYH1_k127_947797_2 methyltransferase activity - - - 0.000000000000000000000000000000005086 134.0
PYH1_k127_959796_0 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 568.0
PYH1_k127_959796_1 Diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 319.0
PYH1_k127_970084_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 2.496e-210 667.0
PYH1_k127_970084_1 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 410.0
PYH1_k127_970084_2 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0