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Overview

ID MAG03143
Name PYH1_bin.35
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family JAHECP01
Genus
Species
Assembly information
Completeness (%) 75.3
Contamination (%) 1.65
GC content (%) 67.0
N50 (bp) 15,141
Genome size (bp) 2,981,125

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2469

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1001110_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 454.0
PYH1_k127_1001110_1 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 398.0
PYH1_k127_1001110_10 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000004089 119.0
PYH1_k127_1001110_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000172 103.0
PYH1_k127_1001110_12 Bacterial DNA-binding protein K03530 - - 0.00000000000000000002779 93.0
PYH1_k127_1001110_2 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 400.0
PYH1_k127_1001110_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001061 285.0
PYH1_k127_1001110_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000001207 238.0
PYH1_k127_1001110_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000229 241.0
PYH1_k127_1001110_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000006533 222.0
PYH1_k127_1001110_7 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000001476 194.0
PYH1_k127_1001110_8 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000001192 181.0
PYH1_k127_1001110_9 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000000000000000000000000006675 138.0
PYH1_k127_1005032_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.218e-215 678.0
PYH1_k127_1005032_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 597.0
PYH1_k127_1005032_2 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 603.0
PYH1_k127_1005032_3 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 541.0
PYH1_k127_1005032_4 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 411.0
PYH1_k127_1005032_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 301.0
PYH1_k127_1005032_6 transferase activity, transferring acyl groups other than amino-acyl groups K03466 - - 0.00000000000000000000000000000000000004447 157.0
PYH1_k127_1009288_0 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000003388 92.0
PYH1_k127_1010696_0 AcrB/AcrD/AcrF family K03296 - - 4.032e-231 769.0
PYH1_k127_1010696_1 Aldo Keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000003439 208.0
PYH1_k127_1010696_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000004714 93.0
PYH1_k127_1010696_3 - - - - 0.000000000000000795 87.0
PYH1_k127_1042162_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000226 141.0
PYH1_k127_1042162_1 COGs COG2442 conserved - - - 0.00000000000000000000000000009019 117.0
PYH1_k127_1042162_2 - - - - 0.00000000000000000000000001956 113.0
PYH1_k127_1042162_3 GIY-YIG catalytic domain - - - 0.0000000000000000001462 95.0
PYH1_k127_105125_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 479.0
PYH1_k127_105125_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 385.0
PYH1_k127_105125_10 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000003835 184.0
PYH1_k127_105125_11 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000208 153.0
PYH1_k127_105125_12 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000001872 111.0
PYH1_k127_105125_13 FHA domain - - - 0.000000000006382 71.0
PYH1_k127_105125_14 Flavin containing amine oxidoreductase - - - 0.0001691 51.0
PYH1_k127_105125_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 370.0
PYH1_k127_105125_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 334.0
PYH1_k127_105125_4 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009 287.0
PYH1_k127_105125_5 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003642 259.0
PYH1_k127_105125_6 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000525 216.0
PYH1_k127_105125_7 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000007799 214.0
PYH1_k127_105125_8 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000009183 211.0
PYH1_k127_105125_9 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000001109 201.0
PYH1_k127_1063024_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 574.0
PYH1_k127_1063024_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000518 72.0
PYH1_k127_1083646_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 536.0
PYH1_k127_1100737_0 PFAM HEPN domain - - - 0.0000000000000000000000000000000000000000000000001183 182.0
PYH1_k127_1100737_1 nucleotidyltransferase activity K07075,K07076 - - 0.00000000000000000000000000000000000000000000001224 176.0
PYH1_k127_1100737_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000001399 171.0
PYH1_k127_113061_0 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 607.0
PYH1_k127_113061_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 559.0
PYH1_k127_113061_2 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 310.0
PYH1_k127_113061_3 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 297.0
PYH1_k127_113061_4 NADPH:quinone reductase activity - - - 0.000000000000000008443 84.0
PYH1_k127_115509_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 311.0
PYH1_k127_115509_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004622 257.0
PYH1_k127_115509_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000071 106.0
PYH1_k127_115509_3 methyltransferase - - - 0.000000000000002482 79.0
PYH1_k127_1181061_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 483.0
PYH1_k127_1181061_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 355.0
PYH1_k127_1181061_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 310.0
PYH1_k127_1181061_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 292.0
PYH1_k127_1181061_4 esterase - - - 0.000000000000000000000000000000000000000000000000000001461 216.0
PYH1_k127_1186773_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 514.0
PYH1_k127_1186773_1 iron-sulfur cluster assembly K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 400.0
PYH1_k127_1186773_2 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 370.0
PYH1_k127_1262689_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 436.0
PYH1_k127_1262689_1 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000000000003627 177.0
PYH1_k127_1262689_2 transport - - - 0.000000000000000996 83.0
PYH1_k127_1262689_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000002021 78.0
PYH1_k127_127564_0 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 2.674e-209 658.0
PYH1_k127_127564_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000001086 266.0
PYH1_k127_1279135_0 enterobactin catabolic process - - - 2.146e-272 880.0
PYH1_k127_1279135_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 6.311e-202 645.0
PYH1_k127_1279135_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000001104 94.0
PYH1_k127_1279135_11 Domain of unknown function (DUF362) - - - 0.0000000000000008821 89.0
PYH1_k127_1279135_12 Bacterial antitoxin of type II TA system, VapB - - - 0.00001451 55.0
PYH1_k127_1279135_13 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0005693 43.0
PYH1_k127_1279135_2 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 561.0
PYH1_k127_1279135_3 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 400.0
PYH1_k127_1279135_4 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 350.0
PYH1_k127_1279135_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 332.0
PYH1_k127_1279135_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 327.0
PYH1_k127_1279135_7 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003903 263.0
PYH1_k127_1279135_8 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000003902 198.0
PYH1_k127_1279135_9 AraC-like ligand binding domain - - - 0.00000000000000000000000285 105.0
PYH1_k127_1318251_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 2.551e-199 636.0
PYH1_k127_1318251_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 570.0
PYH1_k127_1318251_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 358.0
PYH1_k127_1318251_3 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000001786 229.0
PYH1_k127_1318251_4 Putative restriction endonuclease - - - 0.0000000000000000001784 96.0
PYH1_k127_1318251_5 ubiE/COQ5 methyltransferase family - - - 0.0003097 53.0
PYH1_k127_1336494_0 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 492.0
PYH1_k127_1336494_1 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 417.0
PYH1_k127_1336494_2 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 332.0
PYH1_k127_1336494_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000001899 244.0
PYH1_k127_1336494_4 - - - - 0.000000000000000000000000000000000000000000000000000000000005982 224.0
PYH1_k127_1336494_5 response regulator K02479 - - 0.000000000000000000000000000000000000000000000000000001701 198.0
PYH1_k127_1336494_6 Histidine kinase K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000009024 180.0
PYH1_k127_1336494_7 Cytochrome b/b6/petB K00127 - - 0.0000000000000000000006124 109.0
PYH1_k127_1336494_8 Surface antigen - - - 0.000000000009012 77.0
PYH1_k127_1336494_9 - - - - 0.00000000002448 68.0
PYH1_k127_1338472_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.906e-194 631.0
PYH1_k127_1338472_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 310.0
PYH1_k127_1338472_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 296.0
PYH1_k127_1338472_3 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002612 264.0
PYH1_k127_1338472_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000001653 201.0
PYH1_k127_1338472_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000001243 89.0
PYH1_k127_1338472_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000001692 56.0
PYH1_k127_1343043_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001095 257.0
PYH1_k127_1343043_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000779 206.0
PYH1_k127_1343043_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000002717 106.0
PYH1_k127_1369066_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 492.0
PYH1_k127_1369066_1 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 374.0
PYH1_k127_1369066_10 Cation transport protein K03498 - - 0.0000000000000000000003083 100.0
PYH1_k127_1369066_11 PFAM von Willebrand factor type A - - - 0.0000000000000000000003703 108.0
PYH1_k127_1369066_12 PFAM Amino acid-binding ACT - - - 0.000000001032 64.0
PYH1_k127_1369066_2 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 350.0
PYH1_k127_1369066_3 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 320.0
PYH1_k127_1369066_4 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001292 266.0
PYH1_k127_1369066_5 TrkA-C domain K03499 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000007981 230.0
PYH1_k127_1369066_6 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000003341 241.0
PYH1_k127_1369066_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000001308 209.0
PYH1_k127_1369066_8 Belongs to the ompA family - - - 0.000000000000000000000000001588 120.0
PYH1_k127_1369066_9 DoxX K15977 - - 0.0000000000000000000000006456 111.0
PYH1_k127_1406805_0 DNA-templated transcription, initiation - - - 0.000000000000000000000000000001225 128.0
PYH1_k127_1406805_1 MatE - - - 0.00000000000000000000006988 100.0
PYH1_k127_1484766_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 7.5e-322 1010.0
PYH1_k127_1484766_1 topoisomerase K02469 - 5.99.1.3 1.297e-274 867.0
PYH1_k127_1484766_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 471.0
PYH1_k127_1484766_3 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 446.0
PYH1_k127_1484766_4 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 360.0
PYH1_k127_1484766_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000000008857 203.0
PYH1_k127_1484766_6 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000005284 147.0
PYH1_k127_1484766_7 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000005774 109.0
PYH1_k127_1484766_9 MatE - - - 0.0000000000000000004187 88.0
PYH1_k127_1540526_0 transporter K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 413.0
PYH1_k127_1540526_1 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000008381 224.0
PYH1_k127_1547173_0 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 319.0
PYH1_k127_1547173_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005788 264.0
PYH1_k127_1547173_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000005749 198.0
PYH1_k127_1547173_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000000000000000000000000000000000000000000006866 184.0
PYH1_k127_1547173_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000001709 85.0
PYH1_k127_165734_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 466.0
PYH1_k127_165734_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 381.0
PYH1_k127_165734_10 - - - - 0.00000000000000000000002819 111.0
PYH1_k127_165734_12 Protein of unknown function (DUF1569) - - - 0.0000000000000000005265 98.0
PYH1_k127_165734_13 Endoribonuclease L-PSP K09021 - - 0.000000000000005892 87.0
PYH1_k127_165734_14 translation initiation inhibitor, yjgF family K09022 - 3.5.99.10 0.000000000003197 78.0
PYH1_k127_165734_15 Endoribonuclease L-PSP - - - 0.00000000001765 76.0
PYH1_k127_165734_16 - - - - 0.0003884 52.0
PYH1_k127_165734_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 340.0
PYH1_k127_165734_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000004727 256.0
PYH1_k127_165734_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000001852 228.0
PYH1_k127_165734_5 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000008897 204.0
PYH1_k127_165734_6 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.00000000000000000000000000000000000000000000000001072 199.0
PYH1_k127_165734_7 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000008057 191.0
PYH1_k127_165734_8 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000278 121.0
PYH1_k127_165734_9 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000009169 119.0
PYH1_k127_1685806_0 Amidohydrolase family - - - 0.0 1090.0
PYH1_k127_1685806_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000002393 102.0
PYH1_k127_1685806_2 GIY-YIG catalytic domain - - - 0.0000000000000000001597 95.0
PYH1_k127_1685806_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00009953 48.0
PYH1_k127_169103_0 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 496.0
PYH1_k127_169103_1 MgtE intracellular N domain - - - 0.0000000000000000000000000000008658 132.0
PYH1_k127_1719802_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 479.0
PYH1_k127_1719802_1 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 474.0
PYH1_k127_1719802_10 metal cluster binding - - - 0.000000000000000003572 91.0
PYH1_k127_1719802_11 Outer membrane protein beta-barrel domain - - - 0.000000000000001286 85.0
PYH1_k127_1719802_12 - - - - 0.00000007655 65.0
PYH1_k127_1719802_14 - - - - 0.00002848 47.0
PYH1_k127_1719802_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 437.0
PYH1_k127_1719802_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 352.0
PYH1_k127_1719802_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 293.0
PYH1_k127_1719802_5 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002929 255.0
PYH1_k127_1719802_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000001999 241.0
PYH1_k127_1719802_7 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000003264 216.0
PYH1_k127_1719802_8 LVIVD repeat - - - 0.00000000000000000000000000000000001124 146.0
PYH1_k127_1739488_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.308e-203 652.0
PYH1_k127_1739488_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 606.0
PYH1_k127_1739488_10 Pfam:N_methyl_2 - - - 0.00000000000000001069 93.0
PYH1_k127_1739488_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 448.0
PYH1_k127_1739488_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 439.0
PYH1_k127_1739488_4 zinc finger K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 340.0
PYH1_k127_1739488_5 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 312.0
PYH1_k127_1739488_6 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002674 284.0
PYH1_k127_1739488_7 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000000000000000001264 143.0
PYH1_k127_1739488_8 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000002862 141.0
PYH1_k127_1739488_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000001675 113.0
PYH1_k127_1747110_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 398.0
PYH1_k127_1747110_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 334.0
PYH1_k127_1747110_2 Aerotolerance regulator N-terminal - - - 0.00000000000000000000003476 114.0
PYH1_k127_1753883_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 578.0
PYH1_k127_1753883_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000003612 132.0
PYH1_k127_1753883_2 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000002296 93.0
PYH1_k127_1753883_3 PFAM BNR Asp-box repeat - - - 0.00000000000002333 76.0
PYH1_k127_1757809_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.533e-195 618.0
PYH1_k127_1757809_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 547.0
PYH1_k127_1757809_10 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000001537 119.0
PYH1_k127_1757809_12 Sulfatase - - - 0.000000000115 73.0
PYH1_k127_1757809_13 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000001639 62.0
PYH1_k127_1757809_2 Type I phosphodiesterase / nucleotide pyrophosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 461.0
PYH1_k127_1757809_3 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 421.0
PYH1_k127_1757809_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 347.0
PYH1_k127_1757809_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 317.0
PYH1_k127_1757809_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000001491 194.0
PYH1_k127_1757809_7 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000002972 190.0
PYH1_k127_1757809_8 Peptidase, M23 - - - 0.00000000000000000000000000000000000000000000005831 182.0
PYH1_k127_1757809_9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07264 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016763,GO:0033692,GO:0034637,GO:0034645,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.43 0.000000000000000000000000000000000006226 156.0
PYH1_k127_1785051_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.153e-303 942.0
PYH1_k127_1785051_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.952e-239 767.0
PYH1_k127_1785051_10 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000214 133.0
PYH1_k127_1785051_11 BON domain - - - 0.0000000000000000000000000007974 121.0
PYH1_k127_1785051_12 - - - - 0.0000000000000000000001787 103.0
PYH1_k127_1785051_13 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 0.0000000000000000000002082 98.0
PYH1_k127_1785051_14 Acetyltransferase (GNAT) family - - - 0.00000000000000001611 91.0
PYH1_k127_1785051_15 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K03183 - 2.1.1.163,2.1.1.201 0.000000002264 66.0
PYH1_k127_1785051_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.215e-206 649.0
PYH1_k127_1785051_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 349.0
PYH1_k127_1785051_4 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007548 261.0
PYH1_k127_1785051_5 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000005826 227.0
PYH1_k127_1785051_6 Type II secretory pathway component ExeA K02450 - - 0.000000000000000000000000000000000000000000000000000000000000002624 232.0
PYH1_k127_1785051_7 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000002625 220.0
PYH1_k127_1785051_8 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000006997 148.0
PYH1_k127_1785051_9 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000001593 145.0
PYH1_k127_1808616_1 - - - - 0.00000000000000000000000000000002714 134.0
PYH1_k127_1808616_2 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000007518 105.0
PYH1_k127_1816854_0 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 606.0
PYH1_k127_1816854_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 561.0
PYH1_k127_1816854_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 460.0
PYH1_k127_1816854_3 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 439.0
PYH1_k127_1816854_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 404.0
PYH1_k127_1816854_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000005942 155.0
PYH1_k127_1832897_0 cellulose binding - - - 0.0 1119.0
PYH1_k127_1832897_1 toxic component of a K07065 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000002519 65.0
PYH1_k127_1860440_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 393.0
PYH1_k127_1860440_1 DnaB-like helicase N terminal domain K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 317.0
PYH1_k127_1860440_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000001888 196.0
PYH1_k127_1860440_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K02528,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.1.1.182,2.7.1.148 0.000000000000000000000000000000000000000000000000001526 196.0
PYH1_k127_1860440_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000003533 183.0
PYH1_k127_1860440_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000002406 177.0
PYH1_k127_1860440_6 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000007262 158.0
PYH1_k127_1860440_7 Ribosomal protein S18 K02963 - - 0.000000000000000000000002166 104.0
PYH1_k127_1860440_8 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000001278 106.0
PYH1_k127_1860440_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000104 57.0
PYH1_k127_1864585_0 serine-type peptidase activity - - - 1.989e-201 652.0
PYH1_k127_1929673_0 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 579.0
PYH1_k127_1929673_1 Proline racemase K01777,K12658 - 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 539.0
PYH1_k127_1929673_2 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 341.0
PYH1_k127_1929673_3 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003847 288.0
PYH1_k127_1929673_4 acyl carrier protein - - - 0.0000003583 61.0
PYH1_k127_1940344_0 ABC transporter C-terminal domain K06158 - - 1.121e-211 678.0
PYH1_k127_1940344_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 435.0
PYH1_k127_1940344_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
PYH1_k127_1940344_3 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001229 193.0
PYH1_k127_1940344_4 Chaperone - - - 0.000000000001528 78.0
PYH1_k127_1940344_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000021 63.0
PYH1_k127_1940344_6 amine dehydrogenase activity K12132 - 2.7.11.1 0.0001133 56.0
PYH1_k127_1940344_7 Cell division protein K03749 - - 0.000259 55.0
PYH1_k127_1956532_0 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 558.0
PYH1_k127_1956532_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 408.0
PYH1_k127_1956532_2 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 333.0
PYH1_k127_1956532_3 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000001295 224.0
PYH1_k127_1956532_4 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000002735 229.0
PYH1_k127_1956532_5 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000001493 176.0
PYH1_k127_1956532_6 AAA domain K02282 - - 0.000000000000000000000000000000000000000001125 172.0
PYH1_k127_1956532_7 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000002552 167.0
PYH1_k127_1956532_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000001182 122.0
PYH1_k127_1956532_9 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000001332 98.0
PYH1_k127_1957469_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1154.0
PYH1_k127_1957469_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 4.566e-311 969.0
PYH1_k127_1957469_2 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 3.629e-267 836.0
PYH1_k127_1957469_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 3.704e-238 754.0
PYH1_k127_1957469_4 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 619.0
PYH1_k127_1957469_5 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 405.0
PYH1_k127_1957469_6 Putative restriction endonuclease - - - 0.00000000000000000000000002885 119.0
PYH1_k127_1957469_7 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 0.00000000004607 67.0
PYH1_k127_1957569_0 serine-type peptidase activity K08676 - - 0.0 1308.0
PYH1_k127_1957569_1 Sodium:solute symporter family - - - 3.12e-305 947.0
PYH1_k127_1957569_10 Protein of unknown function (DUF1223) - - - 0.00000000001041 71.0
PYH1_k127_1957569_11 peptidyl-tyrosine sulfation - - - 0.00007601 50.0
PYH1_k127_1957569_2 Amidase K01426 - 3.5.1.4 2.449e-226 715.0
PYH1_k127_1957569_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 469.0
PYH1_k127_1957569_4 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 397.0
PYH1_k127_1957569_5 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 342.0
PYH1_k127_1957569_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 329.0
PYH1_k127_1957569_7 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000000001005 166.0
PYH1_k127_1957569_8 Transposase IS200 like K07491 - - 0.000000000000000000000000000000001009 139.0
PYH1_k127_2008041_0 serine-type peptidase activity K08676 - - 0.0 1183.0
PYH1_k127_2008041_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1125.0
PYH1_k127_2008041_10 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 583.0
PYH1_k127_2008041_11 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 485.0
PYH1_k127_2008041_12 Aldehyde dehydrogenase family K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 495.0
PYH1_k127_2008041_13 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 475.0
PYH1_k127_2008041_14 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 438.0
PYH1_k127_2008041_15 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 443.0
PYH1_k127_2008041_16 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 453.0
PYH1_k127_2008041_17 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 396.0
PYH1_k127_2008041_18 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 401.0
PYH1_k127_2008041_19 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 393.0
PYH1_k127_2008041_2 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1080.0
PYH1_k127_2008041_20 PFAM Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 385.0
PYH1_k127_2008041_21 Radical SAM superfamily K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 380.0
PYH1_k127_2008041_22 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 360.0
PYH1_k127_2008041_23 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 310.0
PYH1_k127_2008041_24 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
PYH1_k127_2008041_25 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 294.0
PYH1_k127_2008041_26 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 292.0
PYH1_k127_2008041_27 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002321 274.0
PYH1_k127_2008041_28 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 256.0
PYH1_k127_2008041_29 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000002775 249.0
PYH1_k127_2008041_3 oxidoreductase K00311,K00313 - 1.5.5.1 3.177e-294 912.0
PYH1_k127_2008041_30 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000002487 229.0
PYH1_k127_2008041_32 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000000000000000000000003399 230.0
PYH1_k127_2008041_33 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000001027 225.0
PYH1_k127_2008041_34 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000001367 217.0
PYH1_k127_2008041_35 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000007471 204.0
PYH1_k127_2008041_36 - - - - 0.00000000000000000000000000000000000000000000000005354 197.0
PYH1_k127_2008041_37 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000005446 171.0
PYH1_k127_2008041_38 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000001967 177.0
PYH1_k127_2008041_39 Participates in the control of copper homeostasis K06201 GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.00000000000000000000000000000000000000000002668 170.0
PYH1_k127_2008041_4 PFAM Radical SAM - - - 5.721e-227 718.0
PYH1_k127_2008041_40 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000001333 155.0
PYH1_k127_2008041_41 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000235 168.0
PYH1_k127_2008041_42 NUDIX domain - - - 0.000000000000000000000000000000000000005979 158.0
PYH1_k127_2008041_43 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000004315 151.0
PYH1_k127_2008041_44 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000004593 141.0
PYH1_k127_2008041_45 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000007066 126.0
PYH1_k127_2008041_46 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000001173 131.0
PYH1_k127_2008041_47 Peptidase family M48 - - - 0.00000000000000000000000009017 122.0
PYH1_k127_2008041_48 oxidoreductase activity K12511 - - 0.000000000000000000000008704 114.0
PYH1_k127_2008041_49 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000003515 117.0
PYH1_k127_2008041_5 Peptidase S46 - - - 2.763e-205 660.0
PYH1_k127_2008041_50 lactoylglutathione lyase activity - - - 0.00000000000000000001301 96.0
PYH1_k127_2008041_51 - - - - 0.000000000000002526 91.0
PYH1_k127_2008041_52 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000003496 80.0
PYH1_k127_2008041_53 nucleotidyltransferase activity K07076 - - 0.00000000006987 71.0
PYH1_k127_2008041_54 Transport permease protein K01992 - - 0.0000002743 63.0
PYH1_k127_2008041_55 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000007552 55.0
PYH1_k127_2008041_6 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 1.012e-201 664.0
PYH1_k127_2008041_7 PFAM peptidase - - - 2.437e-197 630.0
PYH1_k127_2008041_8 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 609.0
PYH1_k127_2008041_9 negative regulation of protein lipidation K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 555.0
PYH1_k127_2078323_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1233.0
PYH1_k127_2078323_1 Zinc carboxypeptidase K14054 - - 0.0 1227.0
PYH1_k127_2078323_10 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 340.0
PYH1_k127_2078323_11 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 344.0
PYH1_k127_2078323_12 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 300.0
PYH1_k127_2078323_13 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 306.0
PYH1_k127_2078323_14 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 257.0
PYH1_k127_2078323_15 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004594 259.0
PYH1_k127_2078323_16 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003134 233.0
PYH1_k127_2078323_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000001049 233.0
PYH1_k127_2078323_18 DinB family - - - 0.00000000000000000000000000000000000000000000000002971 184.0
PYH1_k127_2078323_19 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000001823 171.0
PYH1_k127_2078323_2 4Fe-4S dicluster domain K00184 - - 0.0 1179.0
PYH1_k127_2078323_20 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000006565 185.0
PYH1_k127_2078323_21 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000043 169.0
PYH1_k127_2078323_22 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000006802 147.0
PYH1_k127_2078323_23 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000009282 154.0
PYH1_k127_2078323_24 Outer membrane efflux protein - - - 0.0000000000000000000000000000000007912 147.0
PYH1_k127_2078323_25 PFAM methyltransferase - - - 0.000000000000000000000000005962 121.0
PYH1_k127_2078323_26 Thioredoxin domain - - - 0.0000000000000000000002275 102.0
PYH1_k127_2078323_27 - - - - 0.0000000000000000000004307 98.0
PYH1_k127_2078323_28 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000496 98.0
PYH1_k127_2078323_29 - - - - 0.0000000000000000000009754 100.0
PYH1_k127_2078323_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.864e-270 839.0
PYH1_k127_2078323_30 - - - - 0.0000000000000007034 84.0
PYH1_k127_2078323_32 Thioredoxin domain - - - 0.000000000005988 67.0
PYH1_k127_2078323_33 Nitroreductase family - - - 0.0000007159 52.0
PYH1_k127_2078323_4 Polysulphide reductase, NrfD K00185 - - 6.15e-212 666.0
PYH1_k127_2078323_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 599.0
PYH1_k127_2078323_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 418.0
PYH1_k127_2078323_7 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 417.0
PYH1_k127_2078323_8 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 358.0
PYH1_k127_2078323_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 353.0
PYH1_k127_209309_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 337.0
PYH1_k127_211919_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 505.0
PYH1_k127_211919_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002766 283.0
PYH1_k127_211919_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000002134 219.0
PYH1_k127_211919_3 FtsX-like permease family K02004 - - 0.000000000000000000000001165 110.0
PYH1_k127_2122531_0 response regulator - - - 3.935e-215 677.0
PYH1_k127_2122531_1 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 543.0
PYH1_k127_2122531_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 495.0
PYH1_k127_2122531_3 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000002171 184.0
PYH1_k127_2176455_0 transcription factor binding K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 394.0
PYH1_k127_2176455_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004773 246.0
PYH1_k127_2176455_2 - - - - 0.00000000000000004091 89.0
PYH1_k127_2176455_3 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000009193 62.0
PYH1_k127_2189264_0 Transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 562.0
PYH1_k127_2189264_1 Cation transporter/ATPase, N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 493.0
PYH1_k127_2189264_2 - - - - 0.0000000000000000000000000000000001654 137.0
PYH1_k127_2189264_3 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000000003034 111.0
PYH1_k127_2189264_4 HEPN domain - - - 0.000000000000000000004512 99.0
PYH1_k127_2189264_5 HEPN domain - - - 0.00007828 46.0
PYH1_k127_2201043_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1227.0
PYH1_k127_2201043_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1111.0
PYH1_k127_2201043_10 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 481.0
PYH1_k127_2201043_11 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 473.0
PYH1_k127_2201043_12 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 436.0
PYH1_k127_2201043_13 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 418.0
PYH1_k127_2201043_14 Peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 363.0
PYH1_k127_2201043_15 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 358.0
PYH1_k127_2201043_16 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 354.0
PYH1_k127_2201043_17 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 359.0
PYH1_k127_2201043_18 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 359.0
PYH1_k127_2201043_19 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 304.0
PYH1_k127_2201043_2 PFAM Type II secretion system protein E K02652 - - 2.793e-226 713.0
PYH1_k127_2201043_20 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 298.0
PYH1_k127_2201043_21 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000267 287.0
PYH1_k127_2201043_22 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000009625 254.0
PYH1_k127_2201043_23 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000003899 243.0
PYH1_k127_2201043_24 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000001751 218.0
PYH1_k127_2201043_25 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000009811 194.0
PYH1_k127_2201043_26 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000002045 186.0
PYH1_k127_2201043_27 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000008215 171.0
PYH1_k127_2201043_28 PFAM GDSL-like Lipase Acylhydrolase - - - 0.000000000000000000000000000000000000000002223 162.0
PYH1_k127_2201043_29 PFAM microcompartments protein K04027 - - 0.00000000000000000000000000000000000001408 146.0
PYH1_k127_2201043_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 618.0
PYH1_k127_2201043_30 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000003695 149.0
PYH1_k127_2201043_31 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000001503 137.0
PYH1_k127_2201043_32 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000208 122.0
PYH1_k127_2201043_33 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000001119 111.0
PYH1_k127_2201043_35 Pilus assembly protein K02662 - - 0.0000000000000000002882 102.0
PYH1_k127_2201043_36 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.000000000000000002706 91.0
PYH1_k127_2201043_37 - - - - 0.00000000000468 70.0
PYH1_k127_2201043_38 PFAM Fimbrial assembly family protein K02663 - - 0.0000000667 63.0
PYH1_k127_2201043_39 - - - - 0.0000003431 59.0
PYH1_k127_2201043_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 578.0
PYH1_k127_2201043_40 Prokaryotic N-terminal methylation motif K08084 - - 0.00003191 53.0
PYH1_k127_2201043_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 574.0
PYH1_k127_2201043_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 545.0
PYH1_k127_2201043_7 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 510.0
PYH1_k127_2201043_8 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 498.0
PYH1_k127_2201043_9 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 470.0
PYH1_k127_2211417_0 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 5.382e-198 632.0
PYH1_k127_2211417_1 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 536.0
PYH1_k127_2211417_2 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006139 249.0
PYH1_k127_2211417_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000003336 169.0
PYH1_k127_2211417_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000301 157.0
PYH1_k127_2211417_5 - - - - 0.0000000000000000000000000000000000002957 146.0
PYH1_k127_2211417_6 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000746 149.0
PYH1_k127_2211417_7 - - - - 0.0000000000001472 72.0
PYH1_k127_2215310_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.792e-250 785.0
PYH1_k127_2215310_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 392.0
PYH1_k127_2215310_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 374.0
PYH1_k127_2215310_3 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 376.0
PYH1_k127_2215310_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001374 258.0
PYH1_k127_2215310_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000002432 258.0
PYH1_k127_2215310_6 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000001672 116.0
PYH1_k127_2215310_7 Putative regulatory protein - - - 0.0000000000000000001499 96.0
PYH1_k127_2215310_8 Protein of unknown function DUF86 - - - 0.0000168 55.0
PYH1_k127_2228872_0 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 574.0
PYH1_k127_2228872_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 417.0
PYH1_k127_2244195_0 cell adhesion involved in biofilm formation K13735,K20276 - - 6.59e-235 769.0
PYH1_k127_2244195_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 588.0
PYH1_k127_2244195_10 - - - - 0.00000000000000000000000001852 126.0
PYH1_k127_2244195_11 Biotin-lipoyl like K03543 - - 0.0000000000000000001154 104.0
PYH1_k127_2244195_12 D-aminopeptidase K16203 - - 0.00000000000000005647 93.0
PYH1_k127_2244195_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000003688 72.0
PYH1_k127_2244195_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 565.0
PYH1_k127_2244195_3 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 507.0
PYH1_k127_2244195_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 423.0
PYH1_k127_2244195_5 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 418.0
PYH1_k127_2244195_6 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 377.0
PYH1_k127_2244195_7 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000009255 220.0
PYH1_k127_2244195_8 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000009621 156.0
PYH1_k127_2244195_9 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000002856 170.0
PYH1_k127_2262616_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 503.0
PYH1_k127_2262616_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000006271 181.0
PYH1_k127_2262616_2 YceI-like domain - - - 0.000000000000000000000000005064 118.0
PYH1_k127_2262616_3 Phosphopantetheine attachment site K02078 - - 0.0000000001378 69.0
PYH1_k127_2278361_0 metallocarboxypeptidase activity K14054 - - 0.0 1220.0
PYH1_k127_2278361_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 2.581e-255 797.0
PYH1_k127_2278361_2 protein secretion by the type I secretion system K11085 - - 1.486e-242 766.0
PYH1_k127_2278361_3 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 581.0
PYH1_k127_2278361_4 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 265.0
PYH1_k127_2278361_5 - - - - 0.0000000000000000000000007288 114.0
PYH1_k127_2278361_6 Pfam:N_methyl_2 - - - 0.000000001504 67.0
PYH1_k127_2278361_7 TonB dependent receptor K02014 - - 0.00002573 54.0
PYH1_k127_2314530_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 311.0
PYH1_k127_2314530_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000004426 168.0
PYH1_k127_2314530_2 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000001435 132.0
PYH1_k127_2398933_0 PFAM LmbE family protein K22136 - - 1.915e-284 904.0
PYH1_k127_2398933_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 616.0
PYH1_k127_2398933_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 439.0
PYH1_k127_2398933_3 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 325.0
PYH1_k127_2398933_4 serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000188 94.0
PYH1_k127_2398933_5 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.00000004255 55.0
PYH1_k127_2402652_0 BadF BadG BcrA BcrD - - - 0.0 1301.0
PYH1_k127_2402652_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 597.0
PYH1_k127_2402652_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000001026 248.0
PYH1_k127_2402652_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000006624 194.0
PYH1_k127_2402652_4 - - - - 0.000000003258 63.0
PYH1_k127_2479519_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1265.0
PYH1_k127_2479519_1 Molybdenum cofactor sulfurase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 547.0
PYH1_k127_2479519_10 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000407 182.0
PYH1_k127_2479519_11 Polymer-forming cytoskeletal - - - 0.000000000000000004838 89.0
PYH1_k127_2479519_12 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000001235 63.0
PYH1_k127_2479519_2 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 494.0
PYH1_k127_2479519_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 362.0
PYH1_k127_2479519_4 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 342.0
PYH1_k127_2479519_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 316.0
PYH1_k127_2479519_6 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001437 291.0
PYH1_k127_2479519_7 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000252 287.0
PYH1_k127_2479519_8 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 273.0
PYH1_k127_2479519_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000008813 250.0
PYH1_k127_2558796_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 4.122e-283 893.0
PYH1_k127_2558796_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.528e-254 795.0
PYH1_k127_2558796_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.232e-219 686.0
PYH1_k127_2558796_3 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000000000001723 226.0
PYH1_k127_2558796_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000799 145.0
PYH1_k127_2558796_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000003789 126.0
PYH1_k127_2558796_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001205 117.0
PYH1_k127_2585842_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 517.0
PYH1_k127_2585842_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 317.0
PYH1_k127_2590604_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 309.0
PYH1_k127_2590604_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 308.0
PYH1_k127_2590604_2 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000001524 254.0
PYH1_k127_2590604_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000001612 227.0
PYH1_k127_2590604_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000007917 174.0
PYH1_k127_2590604_5 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000002089 160.0
PYH1_k127_2590604_6 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.00000000000002278 82.0
PYH1_k127_2590604_7 trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000004152 61.0
PYH1_k127_259377_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000004275 222.0
PYH1_k127_259377_1 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000008947 220.0
PYH1_k127_259377_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015318,GO:0015679,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030288,GO:0030313,GO:0031975,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1990169 - 0.00003569 49.0
PYH1_k127_2628721_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1065.0
PYH1_k127_2628721_1 Por secretion system C-terminal sorting domain-containing protein - - - 0.0 1055.0
PYH1_k127_2628721_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 357.0
PYH1_k127_2628721_11 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 347.0
PYH1_k127_2628721_12 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 328.0
PYH1_k127_2628721_13 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 320.0
PYH1_k127_2628721_14 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 314.0
PYH1_k127_2628721_15 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 324.0
PYH1_k127_2628721_16 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000008357 258.0
PYH1_k127_2628721_17 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000001057 255.0
PYH1_k127_2628721_18 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000001304 222.0
PYH1_k127_2628721_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000002705 200.0
PYH1_k127_2628721_2 Sortilin, neurotensin receptor 3, - - - 0.0 1026.0
PYH1_k127_2628721_20 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000003441 220.0
PYH1_k127_2628721_21 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000000000000000002412 195.0
PYH1_k127_2628721_22 Protein of unknown function (DUF475) K05794 - - 0.00000000000000000000000000000000000000000005778 169.0
PYH1_k127_2628721_23 domain protein - - - 0.000000000000000000000000000000000000000009535 174.0
PYH1_k127_2628721_24 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000006044 130.0
PYH1_k127_2628721_25 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000002377 108.0
PYH1_k127_2628721_26 Universal bacterial protein YeaZ K14742 - - 0.000000000000000000000009062 110.0
PYH1_k127_2628721_27 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000123 94.0
PYH1_k127_2628721_28 Protein tyrosine kinase - - - 0.0000000000001055 83.0
PYH1_k127_2628721_29 Tetratricopeptide repeat - - - 0.00000006015 63.0
PYH1_k127_2628721_3 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.022e-272 865.0
PYH1_k127_2628721_30 Protein of unknown function (DUF465) - - - 0.000001405 55.0
PYH1_k127_2628721_31 Histidine kinase-like ATPases - - - 0.0003146 50.0
PYH1_k127_2628721_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 8.744e-208 662.0
PYH1_k127_2628721_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 433.0
PYH1_k127_2628721_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 374.0
PYH1_k127_2628721_7 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 374.0
PYH1_k127_2628721_8 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 368.0
PYH1_k127_2628721_9 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 355.0
PYH1_k127_2631401_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000004757 213.0
PYH1_k127_2631401_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000004644 58.0
PYH1_k127_2631401_2 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00006766 51.0
PYH1_k127_2657342_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 466.0
PYH1_k127_2657342_1 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 467.0
PYH1_k127_2657342_2 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 400.0
PYH1_k127_2657342_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000005568 89.0
PYH1_k127_2667836_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 587.0
PYH1_k127_2667836_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 565.0
PYH1_k127_2667836_10 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000004157 184.0
PYH1_k127_2667836_11 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000166 161.0
PYH1_k127_2667836_12 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000000001954 157.0
PYH1_k127_2667836_13 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000295 151.0
PYH1_k127_2667836_14 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000728 124.0
PYH1_k127_2667836_15 cell redox homeostasis - - - 0.000000000001084 76.0
PYH1_k127_2667836_2 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 552.0
PYH1_k127_2667836_3 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 410.0
PYH1_k127_2667836_4 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 406.0
PYH1_k127_2667836_5 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 385.0
PYH1_k127_2667836_6 Pfam Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 374.0
PYH1_k127_2667836_7 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 335.0
PYH1_k127_2667836_8 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 315.0
PYH1_k127_2667836_9 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000003952 212.0
PYH1_k127_2675179_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000005656 228.0
PYH1_k127_2675179_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000001389 204.0
PYH1_k127_2675179_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 - 2.5.1.47 0.00000000000000004905 82.0
PYH1_k127_2692418_0 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000001805 231.0
PYH1_k127_2692418_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000001081 146.0
PYH1_k127_2692418_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000004502 148.0
PYH1_k127_2700230_0 transport - - - 0.0 1230.0
PYH1_k127_2700230_1 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 3.731e-218 702.0
PYH1_k127_2700230_2 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 557.0
PYH1_k127_2700230_3 Carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 496.0
PYH1_k127_2700230_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000006589 251.0
PYH1_k127_2700230_5 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
PYH1_k127_2700230_6 Phosphotransferase enzyme family K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003647 224.0
PYH1_k127_2700230_7 Calcineurin-like phosphoesterase - - - 0.00000000000000000436 96.0
PYH1_k127_2721929_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.338e-255 801.0
PYH1_k127_2721929_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 401.0
PYH1_k127_2721929_2 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 391.0
PYH1_k127_2721929_3 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000001441 134.0
PYH1_k127_2752775_0 Peptidase M14, carboxypeptidase A - - - 3.155e-198 627.0
PYH1_k127_2752775_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000001002 141.0
PYH1_k127_2789395_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 489.0
PYH1_k127_2789395_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 310.0
PYH1_k127_2789395_2 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004665 232.0
PYH1_k127_2789395_3 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000000008918 188.0
PYH1_k127_2791394_0 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
PYH1_k127_2791394_1 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
PYH1_k127_2791394_2 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000005165 156.0
PYH1_k127_2791394_3 response regulator K15012 - - 0.0000003143 61.0
PYH1_k127_2793872_0 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 350.0
PYH1_k127_2793872_1 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000008178 216.0
PYH1_k127_2840535_0 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 411.0
PYH1_k127_2840535_1 Predicted Permease Membrane Region - - - 0.0000000000000000000000000000000000000000000000000000000001926 204.0
PYH1_k127_2840535_2 Protein conserved in bacteria K11891,K11902,K11910 - - 0.0000000000000000000000196 104.0
PYH1_k127_2840535_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000003428 75.0
PYH1_k127_2872596_0 Oligopeptide transporter OPT - - - 1.558e-238 756.0
PYH1_k127_2872596_1 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 523.0
PYH1_k127_2872596_2 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000006221 188.0
PYH1_k127_2872596_3 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000007834 161.0
PYH1_k127_2872596_4 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000002556 157.0
PYH1_k127_2872596_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000711 139.0
PYH1_k127_2872596_6 Polyphosphate AMP phosphotransferase - - - 0.00000000000000000005824 89.0
PYH1_k127_2882374_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.787e-249 779.0
PYH1_k127_2882374_1 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 520.0
PYH1_k127_2886084_0 response regulator K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 433.0
PYH1_k127_2886084_1 response regulator - - - 0.000000000000000000003885 101.0
PYH1_k127_2886084_2 Histidine kinase - - - 0.00000001019 57.0
PYH1_k127_2926477_0 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 464.0
PYH1_k127_2926477_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000875 197.0
PYH1_k127_2926477_2 - - - - 0.0000000000000000000000000000000000003137 152.0
PYH1_k127_2926477_3 PFAM peptidase - - - 0.000000000000000000000000000403 131.0
PYH1_k127_2926477_4 Opacity protein - - - 0.00000000000000000977 93.0
PYH1_k127_2926477_5 DNA-templated transcription, initiation K02405 - - 0.000000000001993 73.0
PYH1_k127_2926477_6 Domain of unknown function (DUF4390) - - - 0.0000000001776 68.0
PYH1_k127_3052973_0 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000003492 184.0
PYH1_k127_3052973_1 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000001528 116.0
PYH1_k127_3052973_2 - - - - 0.00000000000000000000003284 108.0
PYH1_k127_3052973_3 protein-S-isoprenylcysteine methyltransferase - - - 0.0000007014 52.0
PYH1_k127_3052973_4 Transposase is116 is110 is902 family K07486 - - 0.000002823 52.0
PYH1_k127_3069002_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.105e-266 844.0
PYH1_k127_3069002_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 546.0
PYH1_k127_3069002_10 - - - - 0.000005563 50.0
PYH1_k127_3069002_2 Surface antigen variable number K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 392.0
PYH1_k127_3069002_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 322.0
PYH1_k127_3069002_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 295.0
PYH1_k127_3069002_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000016 242.0
PYH1_k127_3069002_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000005883 142.0
PYH1_k127_3069002_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000005509 119.0
PYH1_k127_3069002_8 - - - - 0.00000000000000006162 85.0
PYH1_k127_3069002_9 - - - - 0.000000000002722 73.0
PYH1_k127_3099857_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 361.0
PYH1_k127_3099857_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000002337 205.0
PYH1_k127_3099857_2 solute binding protein K02035 - - 0.000000633 58.0
PYH1_k127_3099857_3 Outer membrane protein beta-barrel domain - - - 0.00001302 55.0
PYH1_k127_3149669_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.04e-318 986.0
PYH1_k127_3149669_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000131 127.0
PYH1_k127_3149669_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002737 81.0
PYH1_k127_3172364_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.000000000000000000000000000000000000000002756 169.0
PYH1_k127_3234092_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1126.0
PYH1_k127_3234092_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 439.0
PYH1_k127_3234092_10 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000000000000006528 138.0
PYH1_k127_3234092_11 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000008439 138.0
PYH1_k127_3234092_12 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000008493 109.0
PYH1_k127_3234092_13 Phosphotransferase System K11189 - - 0.00000000000000000001332 94.0
PYH1_k127_3234092_14 Outer membrane lipoprotein - - - 0.00000000000000000005723 103.0
PYH1_k127_3234092_15 lipopolysaccharide transport K09774 - - 0.000000000000006155 89.0
PYH1_k127_3234092_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 436.0
PYH1_k127_3234092_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 418.0
PYH1_k127_3234092_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 363.0
PYH1_k127_3234092_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 314.0
PYH1_k127_3234092_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 293.0
PYH1_k127_3234092_7 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003251 284.0
PYH1_k127_3234092_8 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000001499 168.0
PYH1_k127_3234092_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000106 163.0
PYH1_k127_325814_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 301.0
PYH1_k127_325814_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000003794 229.0
PYH1_k127_325814_2 SdpI/YhfL protein family - - - 0.000000000000008397 83.0
PYH1_k127_3362646_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1181.0
PYH1_k127_3362646_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.858e-280 883.0
PYH1_k127_3362646_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000001814 158.0
PYH1_k127_3362646_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000001413 125.0
PYH1_k127_3362646_12 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000007449 120.0
PYH1_k127_3362646_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001354 118.0
PYH1_k127_3362646_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004926 104.0
PYH1_k127_3362646_15 PFAM amino acid permease-associated region - - - 0.0000000000002777 70.0
PYH1_k127_3362646_16 STAS domain K04749 - - 0.00000005613 62.0
PYH1_k127_3362646_18 - - - - 0.000006826 56.0
PYH1_k127_3362646_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 473.0
PYH1_k127_3362646_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 379.0
PYH1_k127_3362646_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 358.0
PYH1_k127_3362646_5 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 333.0
PYH1_k127_3362646_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 297.0
PYH1_k127_3362646_7 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000001034 250.0
PYH1_k127_3362646_8 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000002014 169.0
PYH1_k127_3362646_9 Competence protein - - - 0.000000000000000000000000000000000000001148 157.0
PYH1_k127_3365790_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1052.0
PYH1_k127_3365790_1 Succinyl-CoA ligase like flavodoxin domain - - - 1.163e-253 812.0
PYH1_k127_3365790_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 351.0
PYH1_k127_3365790_11 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 322.0
PYH1_k127_3365790_12 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 312.0
PYH1_k127_3365790_13 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 306.0
PYH1_k127_3365790_14 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000231 292.0
PYH1_k127_3365790_15 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002292 278.0
PYH1_k127_3365790_16 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
PYH1_k127_3365790_17 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007074 264.0
PYH1_k127_3365790_18 Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004591 258.0
PYH1_k127_3365790_19 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000003072 220.0
PYH1_k127_3365790_2 Putative carbohydrate binding domain K12373 - 3.2.1.52 5.831e-241 768.0
PYH1_k127_3365790_20 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000001799 205.0
PYH1_k127_3365790_21 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000002705 161.0
PYH1_k127_3365790_22 Putative outer membrane beta-barrel porin, MtrB/PioB K22110 - - 0.00000000000000000000000000000000000003518 165.0
PYH1_k127_3365790_23 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000124 145.0
PYH1_k127_3365790_24 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000003186 146.0
PYH1_k127_3365790_25 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000005499 136.0
PYH1_k127_3365790_26 AMP binding - - - 0.00000000000000000000000000000004245 130.0
PYH1_k127_3365790_27 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000001149 101.0
PYH1_k127_3365790_28 PFAM Alcohol dehydrogenase - - - 0.0000000000000004231 81.0
PYH1_k127_3365790_29 PFAM NifU-like domain - - - 0.00000000000001846 85.0
PYH1_k127_3365790_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 5.49e-219 687.0
PYH1_k127_3365790_30 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.0000000000005727 81.0
PYH1_k127_3365790_31 NosL K19342 - - 0.00000000001349 72.0
PYH1_k127_3365790_32 Redoxin K03564 - 1.11.1.15 0.00000000008223 66.0
PYH1_k127_3365790_33 FeoA K04758 - - 0.00000009992 56.0
PYH1_k127_3365790_34 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000008686 56.0
PYH1_k127_3365790_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 606.0
PYH1_k127_3365790_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 566.0
PYH1_k127_3365790_6 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 535.0
PYH1_k127_3365790_7 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 499.0
PYH1_k127_3365790_8 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 477.0
PYH1_k127_3365790_9 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
PYH1_k127_3368267_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 413.0
PYH1_k127_3368267_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 295.0
PYH1_k127_3375221_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 533.0
PYH1_k127_3375221_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 345.0
PYH1_k127_3375221_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 323.0
PYH1_k127_3375221_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 312.0
PYH1_k127_3375221_4 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 314.0
PYH1_k127_3375221_5 S1 P1 Nuclease - - - 0.0000000000000000000000000000000000000000001787 169.0
PYH1_k127_3375221_6 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000001434 161.0
PYH1_k127_3375221_7 - - - - 0.00000000000000001263 91.0
PYH1_k127_3375221_8 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.000000003187 69.0
PYH1_k127_3376731_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 345.0
PYH1_k127_3376731_1 Response regulator receiver - - - 0.000000000000000000000000000000002056 137.0
PYH1_k127_3394670_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 4.295e-196 617.0
PYH1_k127_3394670_1 protein deglycation K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 392.0
PYH1_k127_3394670_2 Aldo/keto reductase family K00002 - 1.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 331.0
PYH1_k127_3394670_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 296.0
PYH1_k127_3394670_4 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000003479 210.0
PYH1_k127_3420112_0 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 439.0
PYH1_k127_3420112_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 285.0
PYH1_k127_3420112_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000002742 162.0
PYH1_k127_3420112_3 Domain of unknown function (DUF4149) - - - 0.00001217 55.0
PYH1_k127_3420776_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 437.0
PYH1_k127_3420776_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000381 131.0
PYH1_k127_3420776_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000008026 126.0
PYH1_k127_3420776_3 - - - - 0.0000000000000104 89.0
PYH1_k127_3420776_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000001467 61.0
PYH1_k127_3420776_5 oxidoreductase activity - - - 0.0000001079 66.0
PYH1_k127_3420776_6 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.0000221 57.0
PYH1_k127_3420776_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00002464 52.0
PYH1_k127_3421041_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 1.155e-237 759.0
PYH1_k127_3421041_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 511.0
PYH1_k127_3421041_2 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 296.0
PYH1_k127_3421041_3 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000002016 236.0
PYH1_k127_3440164_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001646 195.0
PYH1_k127_3440164_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000001621 205.0
PYH1_k127_3440164_2 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000002261 143.0
PYH1_k127_3441547_0 Dienelactone hydrolase family - - - 5.315e-230 730.0
PYH1_k127_3441547_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 3.654e-205 668.0
PYH1_k127_3441547_10 - - - - 0.0000000004074 74.0
PYH1_k127_3441547_11 oxidoreductase activity - - - 0.0001573 55.0
PYH1_k127_3441547_2 COG1228 Imidazolonepropionase and related K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 582.0
PYH1_k127_3441547_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 362.0
PYH1_k127_3441547_4 Aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 348.0
PYH1_k127_3441547_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000005481 211.0
PYH1_k127_3441547_6 von Willebrand factor, type A - - - 0.000000000000000000000000000000000721 148.0
PYH1_k127_3441547_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000001366 98.0
PYH1_k127_3441547_8 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.0000000000000000006484 95.0
PYH1_k127_3441547_9 energy transducer activity - - - 0.0000000000000004415 91.0
PYH1_k127_3444367_0 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 434.0
PYH1_k127_3444367_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 380.0
PYH1_k127_3444367_10 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) - - - 0.000000000000004359 88.0
PYH1_k127_3444367_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000003256 73.0
PYH1_k127_3444367_12 cytochrome C - - - 0.00000000004878 73.0
PYH1_k127_3444367_13 Protein of unknown function (DUF3347) - - - 0.0000000006938 68.0
PYH1_k127_3444367_14 - - - - 0.000000004182 65.0
PYH1_k127_3444367_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0004662 49.0
PYH1_k127_3444367_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 379.0
PYH1_k127_3444367_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 322.0
PYH1_k127_3444367_4 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 319.0
PYH1_k127_3444367_5 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 307.0
PYH1_k127_3444367_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 299.0
PYH1_k127_3444367_7 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007669 274.0
PYH1_k127_3444367_8 O-methyltransferase - - - 0.0000000000000000000000000000000000008557 149.0
PYH1_k127_3444367_9 membrane - - - 0.0000000000000000000000000000000002158 135.0
PYH1_k127_345370_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 382.0
PYH1_k127_345370_1 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 376.0
PYH1_k127_345370_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000007535 233.0
PYH1_k127_345370_3 Non-specific serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000001084 184.0
PYH1_k127_3466052_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.74e-228 728.0
PYH1_k127_3466052_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 347.0
PYH1_k127_3466052_2 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003412 290.0
PYH1_k127_3466052_3 succinyl-diaminopimelate desuccinylase activity K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000006024 166.0
PYH1_k127_3466052_4 Phosphate acyltransferases K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 0.0000000000000000000000001888 120.0
PYH1_k127_3485861_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
PYH1_k127_3485861_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000001251 174.0
PYH1_k127_3485861_2 to nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000000000000000000000000000327 157.0
PYH1_k127_3485861_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000001564 84.0
PYH1_k127_3490189_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
PYH1_k127_3490189_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000003678 136.0
PYH1_k127_351746_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 413.0
PYH1_k127_351746_1 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 297.0
PYH1_k127_351746_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003161 280.0
PYH1_k127_351746_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004 257.0
PYH1_k127_351746_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000006177 240.0
PYH1_k127_351746_5 BadF/BadG/BcrA/BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000001419 179.0
PYH1_k127_351746_6 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.00000000000000000000000000000000000002894 158.0
PYH1_k127_351746_7 PHP domain protein - - - 0.00000000000000000000000000003617 136.0
PYH1_k127_351746_8 general secretion pathway protein K02456,K02650 - - 0.00000000000000000432 96.0
PYH1_k127_351746_9 Bacterial Ig-like domain (group 1) - - - 0.00009106 54.0
PYH1_k127_3519453_0 enoyl-coa hydratase carnithine racemase K15513 - 4.1.2.44 1.757e-224 708.0
PYH1_k127_3519453_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 6.316e-211 664.0
PYH1_k127_3519453_10 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002599 286.0
PYH1_k127_3519453_11 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000006382 248.0
PYH1_k127_3519453_12 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000001279 196.0
PYH1_k127_3519453_13 NHL repeat - - - 0.0000000000000000000000000000000000000000001995 175.0
PYH1_k127_3519453_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000007613 145.0
PYH1_k127_3519453_2 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 1.533e-199 632.0
PYH1_k127_3519453_3 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 584.0
PYH1_k127_3519453_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 515.0
PYH1_k127_3519453_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 447.0
PYH1_k127_3519453_6 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 437.0
PYH1_k127_3519453_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 392.0
PYH1_k127_3519453_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 367.0
PYH1_k127_3519453_9 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004256 278.0
PYH1_k127_3522321_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 501.0
PYH1_k127_3522321_1 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 453.0
PYH1_k127_3522321_10 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000003222 123.0
PYH1_k127_3522321_11 - - - - 0.00000000000000009793 93.0
PYH1_k127_3522321_12 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000003332 68.0
PYH1_k127_3522321_13 - - - - 0.00000003149 64.0
PYH1_k127_3522321_14 BON domain - - - 0.000001176 59.0
PYH1_k127_3522321_15 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000568 48.0
PYH1_k127_3522321_2 Deoxyhypusine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 376.0
PYH1_k127_3522321_3 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 313.0
PYH1_k127_3522321_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 289.0
PYH1_k127_3522321_5 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 279.0
PYH1_k127_3522321_6 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002305 291.0
PYH1_k127_3522321_7 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000139 239.0
PYH1_k127_3522321_8 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000006609 174.0
PYH1_k127_3522321_9 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000193 155.0
PYH1_k127_3536213_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 499.0
PYH1_k127_3536213_1 TIGRFAM Potassium uptake protein TrkH K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 350.0
PYH1_k127_3536213_2 2Fe-2S -binding domain protein K13483 - - 0.0000000000000000000000000000000000000000000000001385 184.0
PYH1_k127_3538245_0 Sulfatase - - - 8.01e-277 859.0
PYH1_k127_3538245_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 457.0
PYH1_k127_3538245_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 322.0
PYH1_k127_3538245_3 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 319.0
PYH1_k127_3538245_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000001819 177.0
PYH1_k127_3538245_5 - - - - 0.000000000000000000000000003098 120.0
PYH1_k127_3538245_6 PFAM Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000002 113.0
PYH1_k127_3538245_7 PIN domain - - - 0.000000000000000007528 91.0
PYH1_k127_3538250_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5.814e-313 979.0
PYH1_k127_3538250_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.647e-264 840.0
PYH1_k127_3538250_10 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000135 72.0
PYH1_k127_3538250_11 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000363 74.0
PYH1_k127_3538250_12 Ribosomal protein S20 K02968 - - 0.0000000002422 68.0
PYH1_k127_3538250_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 486.0
PYH1_k127_3538250_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 427.0
PYH1_k127_3538250_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
PYH1_k127_3538250_5 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 271.0
PYH1_k127_3538250_6 Transglycosylase SLT domain K01185 - 3.2.1.17 0.000000000000000000000000000000000000002351 155.0
PYH1_k127_3538250_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000002538 156.0
PYH1_k127_3538250_8 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000005166 130.0
PYH1_k127_3538250_9 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.00000000000006194 77.0
PYH1_k127_3543257_0 Zinc carboxypeptidase - - - 3.885e-211 687.0
PYH1_k127_3543257_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 572.0
PYH1_k127_3543257_10 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 419.0
PYH1_k127_3543257_11 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 388.0
PYH1_k127_3543257_12 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 375.0
PYH1_k127_3543257_13 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 375.0
PYH1_k127_3543257_14 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 366.0
PYH1_k127_3543257_15 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 356.0
PYH1_k127_3543257_16 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 338.0
PYH1_k127_3543257_17 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005148 291.0
PYH1_k127_3543257_18 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003758 274.0
PYH1_k127_3543257_19 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000001675 246.0
PYH1_k127_3543257_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 591.0
PYH1_k127_3543257_20 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000002083 240.0
PYH1_k127_3543257_21 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000001553 225.0
PYH1_k127_3543257_22 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000004729 215.0
PYH1_k127_3543257_23 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000005238 192.0
PYH1_k127_3543257_24 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000007809 192.0
PYH1_k127_3543257_25 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000009501 182.0
PYH1_k127_3543257_26 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000005636 173.0
PYH1_k127_3543257_27 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.0000000000000000000000000000000000000000007645 173.0
PYH1_k127_3543257_28 Confers resistance to fosfomycin and deoxycholate K08161 - - 0.00000000000000000000000000000000000000003274 170.0
PYH1_k127_3543257_29 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000001187 153.0
PYH1_k127_3543257_3 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 520.0
PYH1_k127_3543257_30 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000002887 159.0
PYH1_k127_3543257_31 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000008891 148.0
PYH1_k127_3543257_32 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000186 128.0
PYH1_k127_3543257_33 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000002245 126.0
PYH1_k127_3543257_34 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.0000000000000000000000000004216 122.0
PYH1_k127_3543257_35 - - - - 0.000000000000000000000001062 122.0
PYH1_k127_3543257_36 23S rRNA-intervening sequence protein - - - 0.0000000000000000003047 92.0
PYH1_k127_3543257_37 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000001147 95.0
PYH1_k127_3543257_38 Regulatory protein - - - 0.000000000000001175 85.0
PYH1_k127_3543257_39 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000000006121 68.0
PYH1_k127_3543257_4 PFAM Peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 522.0
PYH1_k127_3543257_40 Alpha galactosidase A - - - 0.000000276 63.0
PYH1_k127_3543257_41 methyltransferase - - - 0.00000218 58.0
PYH1_k127_3543257_42 Sulfotransferase - - - 0.000007756 59.0
PYH1_k127_3543257_43 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00008544 47.0
PYH1_k127_3543257_5 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 499.0
PYH1_k127_3543257_6 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 475.0
PYH1_k127_3543257_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 443.0
PYH1_k127_3543257_8 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 426.0
PYH1_k127_3543257_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 422.0
PYH1_k127_3551372_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005743 288.0
PYH1_k127_3551372_1 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000000009045 164.0
PYH1_k127_3551372_2 Adenylate cyclase - - - 0.000158 44.0
PYH1_k127_3571188_0 Transposase DDE domain - - - 2.19e-226 714.0
PYH1_k127_3645835_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 370.0
PYH1_k127_3645835_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000005047 241.0
PYH1_k127_3645835_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000009671 222.0
PYH1_k127_3645835_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000002983 184.0
PYH1_k127_3645835_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000003587 82.0
PYH1_k127_3652513_0 proline dipeptidase activity - - - 7.596e-210 659.0
PYH1_k127_3652513_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 510.0
PYH1_k127_3652513_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 452.0
PYH1_k127_3652513_3 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 422.0
PYH1_k127_3652513_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 350.0
PYH1_k127_3652513_5 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 312.0
PYH1_k127_3652513_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 303.0
PYH1_k127_3652513_7 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000001569 226.0
PYH1_k127_3652513_8 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000001141 98.0
PYH1_k127_36527_0 Flavodoxin-like fold K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 265.0
PYH1_k127_36527_1 Asparaginase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 261.0
PYH1_k127_36527_2 UvrD/REP helicase N-terminal domain K01144 - 3.1.11.5 0.0000000000000000000000000000000000000000000005581 188.0
PYH1_k127_36527_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000004603 104.0
PYH1_k127_36527_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000001388 70.0
PYH1_k127_3700705_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 379.0
PYH1_k127_3700705_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 357.0
PYH1_k127_3700705_2 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 307.0
PYH1_k127_3700705_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001798 269.0
PYH1_k127_3700705_4 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000003552 230.0
PYH1_k127_3700705_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000009501 202.0
PYH1_k127_3700705_6 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000247 162.0
PYH1_k127_3700705_7 cheY-homologous receiver domain K07658 - - 0.0000000000000000000003295 102.0
PYH1_k127_3700705_8 PFAM response regulator receiver - - - 0.000000000000000000007074 104.0
PYH1_k127_3758544_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 475.0
PYH1_k127_3758544_1 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 457.0
PYH1_k127_3767489_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 579.0
PYH1_k127_3767489_1 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 531.0
PYH1_k127_3767489_2 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 473.0
PYH1_k127_3767489_3 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000003219 226.0
PYH1_k127_3767489_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000001737 211.0
PYH1_k127_3767489_5 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000004668 178.0
PYH1_k127_3767489_6 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000003002 168.0
PYH1_k127_3767489_7 - - - - 0.000000000000000000000000000000000000009237 166.0
PYH1_k127_3767489_8 thioesterase K07107 - - 0.0000000000000000000002427 104.0
PYH1_k127_381331_0 import. Responsible for energy coupling to the transport system K02056,K10441,K10542,K10545,K10562,K17204,K17215 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 441.0
PYH1_k127_381331_1 Belongs to the binding-protein-dependent transport system permease family K17203 - - 0.0004167 46.0
PYH1_k127_381331_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0004857 43.0
PYH1_k127_3818183_0 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000004801 222.0
PYH1_k127_3818183_1 Sigma-54 interaction domain K07715 - - 0.0000000000002848 78.0
PYH1_k127_3899961_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003472 246.0
PYH1_k127_3899961_1 ketosteroid isomerase - - - 0.00000000000000000000000000000000000008184 153.0
PYH1_k127_3940490_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000001219 234.0
PYH1_k127_3940490_1 Type II restriction enzyme, methylase subunits - - - 0.000000000000000000000000000000000000001421 166.0
PYH1_k127_3940490_2 Histidine kinase - - - 0.000001414 60.0
PYH1_k127_3966033_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 378.0
PYH1_k127_3966033_1 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 338.0
PYH1_k127_3966033_2 Transcriptional regulator - - - 0.000000000000000000000000000000003391 134.0
PYH1_k127_3966033_3 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000904 119.0
PYH1_k127_3966033_4 Beta-lactamase - - - 0.0004981 44.0
PYH1_k127_4014932_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 424.0
PYH1_k127_4014932_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 365.0
PYH1_k127_4014932_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000009976 114.0
PYH1_k127_4054279_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 8.702e-302 936.0
PYH1_k127_4054279_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 8.792e-208 660.0
PYH1_k127_4054279_10 Receptor - - - 0.0000000001844 73.0
PYH1_k127_4054279_11 Glyoxalase-like domain - - - 0.000000004872 65.0
PYH1_k127_4054279_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 606.0
PYH1_k127_4054279_3 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001693 276.0
PYH1_k127_4054279_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008383 256.0
PYH1_k127_4054279_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000008609 220.0
PYH1_k127_4054279_6 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000003545 196.0
PYH1_k127_4054279_7 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000007411 177.0
PYH1_k127_4054279_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000006098 146.0
PYH1_k127_4054279_9 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000008665 100.0
PYH1_k127_4151456_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 596.0
PYH1_k127_4151456_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 471.0
PYH1_k127_4151456_10 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000169 237.0
PYH1_k127_4151456_11 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000001527 213.0
PYH1_k127_4151456_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000001221 209.0
PYH1_k127_4151456_13 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000000000000000000000000000454 204.0
PYH1_k127_4151456_14 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000006827 187.0
PYH1_k127_4151456_15 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000004938 115.0
PYH1_k127_4151456_16 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000138 114.0
PYH1_k127_4151456_17 Ribosomal L32p protein family K02911 - - 0.0000000000000000000003764 96.0
PYH1_k127_4151456_18 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000002241 62.0
PYH1_k127_4151456_19 TonB C terminal - - - 0.0000004204 61.0
PYH1_k127_4151456_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 414.0
PYH1_k127_4151456_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 389.0
PYH1_k127_4151456_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 317.0
PYH1_k127_4151456_5 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 312.0
PYH1_k127_4151456_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 303.0
PYH1_k127_4151456_7 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007626 280.0
PYH1_k127_4151456_8 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000003164 261.0
PYH1_k127_4151456_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000006405 236.0
PYH1_k127_4171104_0 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
PYH1_k127_4171104_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000134 198.0
PYH1_k127_4171104_2 - - - - 0.0000000000000000000000000000000000000002567 171.0
PYH1_k127_4171104_3 Tryptophan halogenase K21401 - 1.3.99.38 0.00000000000000000000000000002033 121.0
PYH1_k127_4171104_4 GtrA-like protein - - - 0.00000000000000001109 98.0
PYH1_k127_4196504_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 612.0
PYH1_k127_4196504_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 620.0
PYH1_k127_4196504_10 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000001526 177.0
PYH1_k127_4196504_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000009527 161.0
PYH1_k127_4196504_12 DinB family - - - 0.000000000000000000000000000000000001634 154.0
PYH1_k127_4196504_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000004179 143.0
PYH1_k127_4196504_14 spore germination - - - 0.000000000000000000000000000000000004447 151.0
PYH1_k127_4196504_15 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000003631 135.0
PYH1_k127_4196504_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000003124 133.0
PYH1_k127_4196504_17 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000001383 121.0
PYH1_k127_4196504_18 von Willebrand factor, type A K07114 - - 0.000000000000000001778 98.0
PYH1_k127_4196504_19 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000005323 79.0
PYH1_k127_4196504_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 588.0
PYH1_k127_4196504_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000006551 82.0
PYH1_k127_4196504_21 BON domain - - - 0.00000000000006544 81.0
PYH1_k127_4196504_22 HEAT repeats - - - 0.000002794 59.0
PYH1_k127_4196504_23 Putative zinc-finger - - - 0.00009044 53.0
PYH1_k127_4196504_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 488.0
PYH1_k127_4196504_4 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 432.0
PYH1_k127_4196504_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 424.0
PYH1_k127_4196504_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 396.0
PYH1_k127_4196504_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 379.0
PYH1_k127_4196504_8 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000001221 222.0
PYH1_k127_4196504_9 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000131 188.0
PYH1_k127_4202780_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 1.453e-268 845.0
PYH1_k127_4202780_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000004164 121.0
PYH1_k127_4216285_0 PfkB domain protein K00874 - 2.7.1.45 9.295e-198 620.0
PYH1_k127_4216285_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.907e-195 618.0
PYH1_k127_4216285_10 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 292.0
PYH1_k127_4216285_11 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002356 291.0
PYH1_k127_4216285_12 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000001677 187.0
PYH1_k127_4216285_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000000008277 157.0
PYH1_k127_4216285_14 IgA Peptidase M64 - - - 0.00000000000000000000000000000005214 126.0
PYH1_k127_4216285_15 - - - - 0.0000000000000000001535 104.0
PYH1_k127_4216285_16 SnoaL-like polyketide cyclase - - - 0.00000000000004117 79.0
PYH1_k127_4216285_17 - - - - 0.000000000001296 74.0
PYH1_k127_4216285_18 SNARE associated Golgi protein - - - 0.0002999 44.0
PYH1_k127_4216285_2 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 597.0
PYH1_k127_4216285_3 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 539.0
PYH1_k127_4216285_4 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 435.0
PYH1_k127_4216285_5 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 385.0
PYH1_k127_4216285_6 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 393.0
PYH1_k127_4216285_7 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 320.0
PYH1_k127_4216285_8 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 334.0
PYH1_k127_4216285_9 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 325.0
PYH1_k127_422300_0 C-terminus of AA_permease K03294 - - 2.654e-224 704.0
PYH1_k127_422300_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 356.0
PYH1_k127_422300_2 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 282.0
PYH1_k127_422300_3 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001108 278.0
PYH1_k127_422300_4 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000953 249.0
PYH1_k127_422300_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000003276 201.0
PYH1_k127_422300_6 NlpC P60 family protein - - - 0.000000000000000000000000000001347 126.0
PYH1_k127_422300_7 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00005303 47.0
PYH1_k127_4228383_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 1.021e-224 709.0
PYH1_k127_4228383_1 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 587.0
PYH1_k127_4228383_10 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000000001039 156.0
PYH1_k127_4228383_11 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000005117 156.0
PYH1_k127_4228383_12 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000008357 137.0
PYH1_k127_4228383_13 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000002669 139.0
PYH1_k127_4228383_14 PIN domain - - - 0.00000000000000000000000000004803 122.0
PYH1_k127_4228383_15 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000001056 109.0
PYH1_k127_4228383_16 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000003267 84.0
PYH1_k127_4228383_17 positive regulation of growth - - - 0.0000000000000131 78.0
PYH1_k127_4228383_18 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.0000000241 61.0
PYH1_k127_4228383_19 PFAM Bacterial regulatory protein, arsR family - - - 0.00000003237 58.0
PYH1_k127_4228383_2 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 560.0
PYH1_k127_4228383_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 506.0
PYH1_k127_4228383_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 441.0
PYH1_k127_4228383_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 315.0
PYH1_k127_4228383_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 289.0
PYH1_k127_4228383_7 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000122 271.0
PYH1_k127_4228383_8 DREV methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001865 244.0
PYH1_k127_4228383_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000002079 213.0
PYH1_k127_4231266_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 4.093e-213 670.0
PYH1_k127_4231266_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 520.0
PYH1_k127_4231266_2 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
PYH1_k127_4231266_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000002379 223.0
PYH1_k127_4231266_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000005581 110.0
PYH1_k127_4231266_5 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000219 106.0
PYH1_k127_4231411_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 379.0
PYH1_k127_4231411_1 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000005459 118.0
PYH1_k127_4246834_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 495.0
PYH1_k127_4246834_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000002391 205.0
PYH1_k127_4246834_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000002555 74.0
PYH1_k127_4252318_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
PYH1_k127_4252318_1 TonB dependent receptor - - - 0.00000000000000000000000001007 117.0
PYH1_k127_4259080_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 576.0
PYH1_k127_4259080_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K00156,K01652 - 1.2.5.1,2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 469.0
PYH1_k127_4259080_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 422.0
PYH1_k127_4259080_3 Protein of unknown function (DUF1177) - - - 0.0000000000000000002346 93.0
PYH1_k127_4266721_0 Peptidase family M1 domain - - - 1.566e-194 622.0
PYH1_k127_4266721_1 peptidyl-tyrosine sulfation - - - 0.000001613 61.0
PYH1_k127_4266721_2 COG0607 Rhodanese-related sulfurtransferase - - - 0.00005258 49.0
PYH1_k127_428085_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 1.037e-214 677.0
PYH1_k127_428085_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 480.0
PYH1_k127_428085_10 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000005407 138.0
PYH1_k127_428085_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000002003 94.0
PYH1_k127_428085_12 aminopeptidase activity K07004 - - 0.0000000000008664 69.0
PYH1_k127_428085_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 350.0
PYH1_k127_428085_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 313.0
PYH1_k127_428085_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
PYH1_k127_428085_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
PYH1_k127_428085_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000001243 243.0
PYH1_k127_428085_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000005418 183.0
PYH1_k127_428085_8 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000002553 185.0
PYH1_k127_428085_9 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000008176 168.0
PYH1_k127_4304000_0 PFAM Prolyl oligopeptidase family - - - 4.572e-231 734.0
PYH1_k127_4304000_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 503.0
PYH1_k127_4304000_10 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000001342 166.0
PYH1_k127_4304000_11 glycine D-amino acid - - - 0.00000000000000000000000000000000004657 149.0
PYH1_k127_4304000_12 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000003198 55.0
PYH1_k127_4304000_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 494.0
PYH1_k127_4304000_3 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 351.0
PYH1_k127_4304000_4 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 331.0
PYH1_k127_4304000_5 4Fe-4S binding domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 313.0
PYH1_k127_4304000_6 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000116 264.0
PYH1_k127_4304000_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
PYH1_k127_4304000_8 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001597 260.0
PYH1_k127_4304000_9 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003094 250.0
PYH1_k127_4316766_0 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000036 233.0
PYH1_k127_433429_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 546.0
PYH1_k127_433429_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 481.0
PYH1_k127_433429_10 allophanate hydrolase subunit 2 K01457,K01941,K06350 - 3.5.1.54,6.3.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
PYH1_k127_433429_11 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000001528 222.0
PYH1_k127_433429_12 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000008637 209.0
PYH1_k127_433429_13 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000005381 201.0
PYH1_k127_433429_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000001912 195.0
PYH1_k127_433429_15 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000002728 152.0
PYH1_k127_433429_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000389 141.0
PYH1_k127_433429_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K10810 - 2.5.1.3,5.3.99.10 0.0000000000000000000000000000000745 134.0
PYH1_k127_433429_18 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000000003612 129.0
PYH1_k127_433429_19 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000001318 121.0
PYH1_k127_433429_2 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 424.0
PYH1_k127_433429_20 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000007126 112.0
PYH1_k127_433429_21 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000008097 103.0
PYH1_k127_433429_22 - - - - 0.000000000000000000000008862 113.0
PYH1_k127_433429_23 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000001809 109.0
PYH1_k127_433429_24 Helix-turn-helix domain K15539 - - 0.000000000000000000002838 104.0
PYH1_k127_433429_25 Tetratricopeptide repeats - - - 0.00000000000000003195 96.0
PYH1_k127_433429_26 Belongs to the UPF0109 family K06960 - - 0.000000003394 63.0
PYH1_k127_433429_27 RDD family - - - 0.0000000267 65.0
PYH1_k127_433429_28 - - - - 0.0000002071 58.0
PYH1_k127_433429_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 317.0
PYH1_k127_433429_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 314.0
PYH1_k127_433429_5 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 320.0
PYH1_k127_433429_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 305.0
PYH1_k127_433429_7 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 287.0
PYH1_k127_433429_8 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 291.0
PYH1_k127_433429_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000002382 287.0
PYH1_k127_4337669_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 336.0
PYH1_k127_4337669_1 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 303.0
PYH1_k127_4337669_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 292.0
PYH1_k127_4337669_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000003266 199.0
PYH1_k127_4337669_4 serine-type peptidase activity - - - 0.000000000000001599 77.0
PYH1_k127_4352121_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 427.0
PYH1_k127_4352121_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000009787 192.0
PYH1_k127_4352121_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000001278 184.0
PYH1_k127_4361235_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 2.134e-285 885.0
PYH1_k127_4361235_1 Cyclic nucleotide-monophosphate binding domain - - - 9.01e-200 632.0
PYH1_k127_4361235_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 567.0
PYH1_k127_4361235_3 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 305.0
PYH1_k127_4361235_4 mRNA binding K07339 - - 0.00000001633 57.0
PYH1_k127_4361235_5 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000001086 50.0
PYH1_k127_4361235_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0001065 51.0
PYH1_k127_4365675_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 555.0
PYH1_k127_4365675_1 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 511.0
PYH1_k127_4365675_10 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000004681 63.0
PYH1_k127_4365675_11 - - - - 0.000683 49.0
PYH1_k127_4365675_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 444.0
PYH1_k127_4365675_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 388.0
PYH1_k127_4365675_4 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008129 299.0
PYH1_k127_4365675_5 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001336 290.0
PYH1_k127_4365675_6 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002605 250.0
PYH1_k127_4365675_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000179 203.0
PYH1_k127_4365675_8 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000002303 161.0
PYH1_k127_4365675_9 Putative adhesin - - - 0.00000000000000000000000000000004962 138.0
PYH1_k127_4432195_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 494.0
PYH1_k127_4432195_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 439.0
PYH1_k127_4432195_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 423.0
PYH1_k127_4432195_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 391.0
PYH1_k127_4432195_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 364.0
PYH1_k127_4432195_5 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
PYH1_k127_4432195_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
PYH1_k127_4432195_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000255 287.0
PYH1_k127_4432195_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000006669 130.0
PYH1_k127_4432195_9 Evidence 5 No homology to any previously reported sequences - - - 0.0000003951 59.0
PYH1_k127_4452409_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 4.793e-251 785.0
PYH1_k127_4477063_0 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 238.0
PYH1_k127_4477063_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000005312 166.0
PYH1_k127_4477063_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000007309 109.0
PYH1_k127_4482715_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 396.0
PYH1_k127_4482715_1 Von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 289.0
PYH1_k127_4482715_2 von Willebrand factor type A - - - 0.00006222 50.0
PYH1_k127_4535527_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 430.0
PYH1_k127_4535527_1 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 404.0
PYH1_k127_4535527_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 331.0
PYH1_k127_4535527_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 320.0
PYH1_k127_4535527_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 291.0
PYH1_k127_4535527_5 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000002036 231.0
PYH1_k127_4535527_6 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000001298 149.0
PYH1_k127_4535527_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000001271 134.0
PYH1_k127_4535527_8 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000001523 111.0
PYH1_k127_4562075_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000001458 211.0
PYH1_k127_4562075_1 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000003352 128.0
PYH1_k127_4562075_2 Caspase domain - - - 0.00000000000000000000000000004137 128.0
PYH1_k127_4661780_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 393.0
PYH1_k127_4661780_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 294.0
PYH1_k127_4677694_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 389.0
PYH1_k127_4677694_1 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 376.0
PYH1_k127_4677694_10 thioesterase K07107 - - 0.00000000000000000000000000000008787 138.0
PYH1_k127_4677694_11 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00009259 53.0
PYH1_k127_4677694_12 Peptidoglycan-binding LysM - - - 0.0001565 52.0
PYH1_k127_4677694_2 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 295.0
PYH1_k127_4677694_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 296.0
PYH1_k127_4677694_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007726 263.0
PYH1_k127_4677694_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000006542 250.0
PYH1_k127_4677694_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000007698 182.0
PYH1_k127_4677694_7 Outer membrane lipoprotein K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000002854 163.0
PYH1_k127_4677694_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000003019 162.0
PYH1_k127_4677694_9 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.000000000000000000000000000000001826 140.0
PYH1_k127_4709940_0 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 432.0
PYH1_k127_4709940_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 416.0
PYH1_k127_4709940_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000003595 213.0
PYH1_k127_4709940_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000001143 63.0
PYH1_k127_473385_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 509.0
PYH1_k127_473385_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 467.0
PYH1_k127_473385_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000006948 73.0
PYH1_k127_4747196_0 Tricorn protease homolog K08676 - - 0.0 1335.0
PYH1_k127_4747196_1 PFAM amidohydrolase - - - 2.267e-235 747.0
PYH1_k127_4747196_10 DinB family - - - 0.0000000002262 67.0
PYH1_k127_4747196_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 458.0
PYH1_k127_4747196_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 435.0
PYH1_k127_4747196_4 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 393.0
PYH1_k127_4747196_5 methyltransferase K09846,K21255 - 2.1.1.210 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 326.0
PYH1_k127_4747196_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005943 243.0
PYH1_k127_4747196_7 homoserine transmembrane transporter activity K06600,K06895 - - 0.000000000000000000000000000000000000000002011 164.0
PYH1_k127_4747196_8 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000002267 161.0
PYH1_k127_4747196_9 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000005865 159.0
PYH1_k127_4760107_0 lytic transglycosylase activity K08309 - - 0.0000000000000000000000000002131 121.0
PYH1_k127_4760107_1 COG1555 DNA uptake protein and related DNA-binding proteins - - - 0.000000178 64.0
PYH1_k127_4761476_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.596e-293 932.0
PYH1_k127_4761476_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000006435 175.0
PYH1_k127_4761476_2 - - - - 0.00004552 50.0
PYH1_k127_4810583_0 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 2.94e-292 912.0
PYH1_k127_4810583_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 500.0
PYH1_k127_4810583_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 372.0
PYH1_k127_4810583_3 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000009494 261.0
PYH1_k127_4810583_4 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000002057 255.0
PYH1_k127_4810583_5 Protein of unknown function (DUF1295) - - - 0.00003972 53.0
PYH1_k127_4869641_0 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 366.0
PYH1_k127_4869641_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 293.0
PYH1_k127_4869641_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000008516 89.0
PYH1_k127_497482_0 Tricorn protease homolog - - - 0.0 1437.0
PYH1_k127_497482_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 612.0
PYH1_k127_497482_10 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000001925 76.0
PYH1_k127_497482_11 - - - - 0.0003865 49.0
PYH1_k127_497482_2 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 424.0
PYH1_k127_497482_3 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008789 255.0
PYH1_k127_497482_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000945 184.0
PYH1_k127_497482_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000003849 182.0
PYH1_k127_497482_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000008095 163.0
PYH1_k127_497482_7 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000001664 168.0
PYH1_k127_497482_8 - - - - 0.000000000000000000000000000008355 132.0
PYH1_k127_497482_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000004469 118.0
PYH1_k127_4977095_0 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 523.0
PYH1_k127_4977095_1 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 417.0
PYH1_k127_4977095_2 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 389.0
PYH1_k127_4977095_3 PFAM Formiminotransferase K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 354.0
PYH1_k127_4977095_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000009232 201.0
PYH1_k127_4977095_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000006148 148.0
PYH1_k127_4977095_6 - - - - 0.00000007942 64.0
PYH1_k127_4977095_7 Bacterial regulatory protein, Fis family - - - 0.000006552 54.0
PYH1_k127_5034923_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 442.0
PYH1_k127_5034923_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 436.0
PYH1_k127_5034923_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
PYH1_k127_5034923_3 TIGRFAM hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000004174 158.0
PYH1_k127_5035595_0 Zinc carboxypeptidase - - - 0.0 1053.0
PYH1_k127_5035595_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.411e-303 940.0
PYH1_k127_5035595_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
PYH1_k127_5035595_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000001207 206.0
PYH1_k127_5035595_12 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000001551 211.0
PYH1_k127_5035595_13 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000008614 115.0
PYH1_k127_5035595_14 transcriptional regulator, ArsR family protein K03892 - - 0.000000000000000000000003213 109.0
PYH1_k127_5035595_15 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000208 91.0
PYH1_k127_5035595_16 Trypsin K04771 - 3.4.21.107 0.00000000000002667 85.0
PYH1_k127_5035595_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000006938 82.0
PYH1_k127_5035595_18 PFAM Peptidase family M28 - - - 0.0000004772 62.0
PYH1_k127_5035595_2 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 1.316e-301 946.0
PYH1_k127_5035595_3 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 9.319e-265 826.0
PYH1_k127_5035595_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 524.0
PYH1_k127_5035595_5 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 487.0
PYH1_k127_5035595_6 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 372.0
PYH1_k127_5035595_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 363.0
PYH1_k127_5035595_8 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 337.0
PYH1_k127_5035595_9 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 340.0
PYH1_k127_5041885_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 341.0
PYH1_k127_5041885_1 ABC transporter K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001704 274.0
PYH1_k127_5041885_2 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
PYH1_k127_5041885_3 - - - - 0.00000000000000000000000000000000000000000000000007517 181.0
PYH1_k127_5041885_4 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.000000000000000000000000000000000000000000001997 181.0
PYH1_k127_5041885_5 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.000000000000000000000000000000000000000004606 179.0
PYH1_k127_5062371_0 - - - - 2.626e-245 783.0
PYH1_k127_5084486_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1651.0
PYH1_k127_5084486_1 Domain of unknown function (DUF362) - - - 5.43e-209 658.0
PYH1_k127_5084486_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 342.0
PYH1_k127_5084486_11 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 305.0
PYH1_k127_5084486_12 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004388 280.0
PYH1_k127_5084486_13 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000009067 239.0
PYH1_k127_5084486_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000004554 188.0
PYH1_k127_5084486_15 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000001036 177.0
PYH1_k127_5084486_16 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000007839 147.0
PYH1_k127_5084486_17 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000003541 128.0
PYH1_k127_5084486_18 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000005686 130.0
PYH1_k127_5084486_19 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000002785 100.0
PYH1_k127_5084486_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 576.0
PYH1_k127_5084486_20 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000003465 102.0
PYH1_k127_5084486_22 TRAM domain - - - 0.000000000002998 73.0
PYH1_k127_5084486_23 SMART Elongator protein 3 MiaB NifB K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000001032 70.0
PYH1_k127_5084486_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 514.0
PYH1_k127_5084486_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 501.0
PYH1_k127_5084486_5 BAAT / Acyl-CoA thioester hydrolase C terminal K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 467.0
PYH1_k127_5084486_6 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
PYH1_k127_5084486_7 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 412.0
PYH1_k127_5084486_8 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 414.0
PYH1_k127_5084486_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 404.0
PYH1_k127_5089637_0 PFAM Radical SAM - - - 0.0 1110.0
PYH1_k127_5089637_1 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1095.0
PYH1_k127_5089637_10 radical SAM domain protein K15045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 469.0
PYH1_k127_5089637_11 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 458.0
PYH1_k127_5089637_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 440.0
PYH1_k127_5089637_13 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 441.0
PYH1_k127_5089637_14 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 439.0
PYH1_k127_5089637_15 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 421.0
PYH1_k127_5089637_16 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 422.0
PYH1_k127_5089637_17 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 381.0
PYH1_k127_5089637_18 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 379.0
PYH1_k127_5089637_19 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 371.0
PYH1_k127_5089637_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.059e-290 904.0
PYH1_k127_5089637_20 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 374.0
PYH1_k127_5089637_21 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 392.0
PYH1_k127_5089637_22 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 349.0
PYH1_k127_5089637_23 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 302.0
PYH1_k127_5089637_24 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003946 285.0
PYH1_k127_5089637_25 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 278.0
PYH1_k127_5089637_26 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003923 279.0
PYH1_k127_5089637_27 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000008856 265.0
PYH1_k127_5089637_28 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
PYH1_k127_5089637_29 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000001991 250.0
PYH1_k127_5089637_3 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.72e-231 743.0
PYH1_k127_5089637_30 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000007282 244.0
PYH1_k127_5089637_31 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000011 224.0
PYH1_k127_5089637_32 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000008857 203.0
PYH1_k127_5089637_33 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000762 212.0
PYH1_k127_5089637_34 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000001131 193.0
PYH1_k127_5089637_35 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000152 200.0
PYH1_k127_5089637_36 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000002707 192.0
PYH1_k127_5089637_37 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.000000000000000000000000000000000000000000000002294 175.0
PYH1_k127_5089637_38 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000025 171.0
PYH1_k127_5089637_39 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000001205 166.0
PYH1_k127_5089637_4 Response regulator receiver - - - 2.945e-203 642.0
PYH1_k127_5089637_40 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000493 153.0
PYH1_k127_5089637_41 DinB family - - - 0.00000000000000000000000000000001785 133.0
PYH1_k127_5089637_42 von Willebrand factor, type A - - - 0.000000000000000000000000000004619 132.0
PYH1_k127_5089637_43 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000001222 121.0
PYH1_k127_5089637_44 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000001554 123.0
PYH1_k127_5089637_45 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000001735 109.0
PYH1_k127_5089637_46 Protein of unknown function (DUF1706) - - - 0.000000000000000000001903 101.0
PYH1_k127_5089637_47 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000005741 98.0
PYH1_k127_5089637_48 ACT domain - - - 0.00000000000000001111 88.0
PYH1_k127_5089637_49 - - - - 0.0000000000359 68.0
PYH1_k127_5089637_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.08e-198 636.0
PYH1_k127_5089637_50 gas vesicle protein - - - 0.0000117 50.0
PYH1_k127_5089637_6 catalyzes the formation of indole and pyruvate from tryptophan K01667 - 4.1.99.1 5.019e-198 628.0
PYH1_k127_5089637_7 Bacterial DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 614.0
PYH1_k127_5089637_8 Recombination factor protein RarA K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 509.0
PYH1_k127_5089637_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 511.0
PYH1_k127_5092328_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.036e-219 691.0
PYH1_k127_5092328_1 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
PYH1_k127_5092328_2 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 295.0
PYH1_k127_5092328_3 With GsiBCD is involved in glutathione import K02031,K02032 - - 0.00000000000000000000002187 108.0
PYH1_k127_5105130_0 PFAM Glycosyl Hydrolase - - - 0.0 1047.0
PYH1_k127_5105130_1 Serine hydrolase (FSH1) - - - 4.516e-251 793.0
PYH1_k127_5105130_10 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 359.0
PYH1_k127_5105130_11 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 344.0
PYH1_k127_5105130_12 Amidohydrolase family K01465,K01466 - 3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 343.0
PYH1_k127_5105130_13 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
PYH1_k127_5105130_14 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000007351 261.0
PYH1_k127_5105130_15 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000087 231.0
PYH1_k127_5105130_16 Thiamine-binding protein - - - 0.0000000000000000000000000000000000000000005181 169.0
PYH1_k127_5105130_17 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001701 115.0
PYH1_k127_5105130_18 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000006474 113.0
PYH1_k127_5105130_19 - - - - 0.0000000000000000001345 91.0
PYH1_k127_5105130_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.622e-247 773.0
PYH1_k127_5105130_20 - - - - 0.000000005438 59.0
PYH1_k127_5105130_21 membrane - - - 0.000009048 57.0
PYH1_k127_5105130_3 lysine biosynthetic process via aminoadipic acid - - - 3.198e-241 768.0
PYH1_k127_5105130_4 membrane K07027,K14205 - 2.3.2.3 6.006e-218 704.0
PYH1_k127_5105130_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 626.0
PYH1_k127_5105130_6 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 591.0
PYH1_k127_5105130_7 Lamin Tail Domain K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 588.0
PYH1_k127_5105130_8 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 478.0
PYH1_k127_5105130_9 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 448.0
PYH1_k127_5112363_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 606.0
PYH1_k127_5112363_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 344.0
PYH1_k127_5112363_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 335.0
PYH1_k127_5112363_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 291.0
PYH1_k127_5112363_4 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000001571 194.0
PYH1_k127_5112363_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000001132 198.0
PYH1_k127_5112363_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000007782 155.0
PYH1_k127_5112363_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000001368 131.0
PYH1_k127_5112363_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000004589 123.0
PYH1_k127_5112363_9 outer membrane autotransporter barrel domain protein - - - 0.000008291 56.0
PYH1_k127_5116568_1 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 372.0
PYH1_k127_5116568_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 331.0
PYH1_k127_5116568_3 molybdenum ion binding K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 305.0
PYH1_k127_5116568_4 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
PYH1_k127_5116568_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
PYH1_k127_5120405_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 418.0
PYH1_k127_5120405_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000566 281.0
PYH1_k127_5134481_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 426.0
PYH1_k127_5134481_1 Acetyltransferase (GNAT) domain - - - 0.000007896 51.0
PYH1_k127_5145436_0 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 489.0
PYH1_k127_5145436_1 Tripartite ATP-independent periplasmic transporter, DctM component K03300 - - 0.0000000000000000000000000000000000000000000000000000000003131 205.0
PYH1_k127_5145436_2 - - - - 0.00000000000006151 72.0
PYH1_k127_5163402_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0 1246.0
PYH1_k127_5163402_1 Sulfatase - - - 0.00000000003115 64.0
PYH1_k127_5188811_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000001201 174.0
PYH1_k127_5188811_1 OsmC-like protein K04063 - - 0.0000000000000000002151 101.0
PYH1_k127_5188811_2 Domain of unknown function (DUF4203) - - - 0.0000001006 61.0
PYH1_k127_5195024_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 6.474e-197 620.0
PYH1_k127_5195024_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 599.0
PYH1_k127_5195024_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 568.0
PYH1_k127_5195024_3 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 352.0
PYH1_k127_5216038_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 412.0
PYH1_k127_5216038_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 307.0
PYH1_k127_5216038_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000004047 156.0
PYH1_k127_5216038_3 amine dehydrogenase activity - - - 0.0000000000000000000000001047 121.0
PYH1_k127_5216038_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000003438 84.0
PYH1_k127_522730_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1370.0
PYH1_k127_522730_1 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 447.0
PYH1_k127_522730_2 Competence protein K02238 - - 0.000000000000000311 93.0
PYH1_k127_522730_3 PFAM PEGA domain - - - 0.000000000005268 69.0
PYH1_k127_5279929_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 514.0
PYH1_k127_5324368_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 596.0
PYH1_k127_5324368_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 522.0
PYH1_k127_5324368_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 468.0
PYH1_k127_5324368_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 463.0
PYH1_k127_5324368_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 350.0
PYH1_k127_5324368_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 299.0
PYH1_k127_5324368_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001588 282.0
PYH1_k127_5324368_7 Peptidase M56 - - - 0.0000000001764 72.0
PYH1_k127_5324368_8 guanyl-nucleotide exchange factor activity K14475,K20276 - - 0.00006727 56.0
PYH1_k127_5339863_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 366.0
PYH1_k127_5339863_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001159 282.0
PYH1_k127_5339863_2 transport system involved in gliding motility, auxiliary K01992 - - 0.0000000000000000004295 93.0
PYH1_k127_5342037_0 Imidazolonepropionase and related - - - 1.34e-200 657.0
PYH1_k127_5342037_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 588.0
PYH1_k127_5342037_10 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 318.0
PYH1_k127_5342037_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000005389 275.0
PYH1_k127_5342037_12 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000002192 226.0
PYH1_k127_5342037_13 rRNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000185 222.0
PYH1_k127_5342037_14 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000006022 194.0
PYH1_k127_5342037_15 Disulphide isomerase - - - 0.0000000000000000000000000000000000000000000000000001243 188.0
PYH1_k127_5342037_16 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000002543 195.0
PYH1_k127_5342037_17 Universal stress protein family - - - 0.0000000000000000000000000000000000000000006934 161.0
PYH1_k127_5342037_18 - - - - 0.000000000000000000000000000000000000000001791 168.0
PYH1_k127_5342037_19 Response regulator receiver - - - 0.00000000000000000000000000000000000000001025 173.0
PYH1_k127_5342037_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 535.0
PYH1_k127_5342037_20 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000000000002564 156.0
PYH1_k127_5342037_21 Putative restriction endonuclease - - - 0.00000000000000000000000000000000001802 138.0
PYH1_k127_5342037_22 Domain of unknown function (DUF4177) - - - 0.00000000000001593 75.0
PYH1_k127_5342037_23 - - - - 0.00000000001156 69.0
PYH1_k127_5342037_24 Putative regulatory protein - - - 0.000000005181 59.0
PYH1_k127_5342037_25 Acetyltransferase (GNAT) family - - - 0.000000006631 66.0
PYH1_k127_5342037_26 subunit of a heme lyase K02198,K02200 - - 0.00000005193 63.0
PYH1_k127_5342037_27 Cytochrome c - - - 0.00004476 52.0
PYH1_k127_5342037_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 513.0
PYH1_k127_5342037_4 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 470.0
PYH1_k127_5342037_5 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 476.0
PYH1_k127_5342037_6 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 376.0
PYH1_k127_5342037_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 319.0
PYH1_k127_5342037_8 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 316.0
PYH1_k127_5342037_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 316.0
PYH1_k127_5357460_0 Glycogen debranching enzyme - - - 2.886e-228 741.0
PYH1_k127_5357460_1 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 311.0
PYH1_k127_5357460_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000004499 72.0
PYH1_k127_5357460_2 ABC-type multidrug transport system ATPase K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 295.0
PYH1_k127_5357460_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
PYH1_k127_5357460_4 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005537 267.0
PYH1_k127_5357460_5 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000005238 224.0
PYH1_k127_5357460_6 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000001108 169.0
PYH1_k127_5357460_7 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.0000000000000000000000000000000000000000001329 162.0
PYH1_k127_5357460_8 Cyclic phosphodiesterase-like protein - - - 0.00000000000000005885 92.0
PYH1_k127_5357899_0 glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 616.0
PYH1_k127_5357899_1 glycosyl hydrolase, family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000004698 202.0
PYH1_k127_5357899_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000003436 81.0
PYH1_k127_5359372_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 2.33e-253 802.0
PYH1_k127_5382862_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 514.0
PYH1_k127_5382862_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 451.0
PYH1_k127_5382862_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 403.0
PYH1_k127_5382862_3 Cell division protein FtsQ K03589 - - 0.000000000001493 78.0
PYH1_k127_5382862_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000001359 61.0
PYH1_k127_5397970_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 383.0
PYH1_k127_5450830_0 Beta-L-arabinofuranosidase, GH127 - - - 3.642e-239 755.0
PYH1_k127_5450830_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 432.0
PYH1_k127_5450830_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000002733 218.0
PYH1_k127_5450830_3 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000000000000000000225 196.0
PYH1_k127_5450830_4 PIN domain K18828 - - 0.000000000000000000000000000000005083 132.0
PYH1_k127_5450830_5 - - - - 0.0000000000002312 73.0
PYH1_k127_5450830_6 Response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes K07712 - - 0.0001373 48.0
PYH1_k127_5473213_0 Hydrolase CocE NonD family - - - 0.0 1011.0
PYH1_k127_5473213_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 3.481e-267 834.0
PYH1_k127_5473213_11 Protein tyrosine kinase - - - 0.000000000000000000006971 97.0
PYH1_k127_5473213_12 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000001072 94.0
PYH1_k127_5473213_13 CAAX protease self-immunity K07052 - - 0.0000000000000000169 94.0
PYH1_k127_5473213_2 PFAM Carbohydrate kinase K00853 - 2.7.1.16 1.271e-259 808.0
PYH1_k127_5473213_3 L-fucose isomerase, C-terminal domain - - - 3.092e-243 758.0
PYH1_k127_5473213_4 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 345.0
PYH1_k127_5473213_5 PFAM Class II aldolase K03077 - 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 304.0
PYH1_k127_5473213_6 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001048 286.0
PYH1_k127_5473213_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001991 261.0
PYH1_k127_5473213_8 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
PYH1_k127_5473213_9 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000742 214.0
PYH1_k127_5520214_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 7.258e-253 806.0
PYH1_k127_5520214_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 583.0
PYH1_k127_5520214_10 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001515 242.0
PYH1_k127_5520214_11 Phospholipase/Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000003828 227.0
PYH1_k127_5520214_12 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000003038 177.0
PYH1_k127_5520214_13 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000004115 160.0
PYH1_k127_5520214_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000001096 139.0
PYH1_k127_5520214_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000002246 115.0
PYH1_k127_5520214_16 Sigma-70, region 4 K03088 - - 0.0000000000000000000000003995 112.0
PYH1_k127_5520214_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 549.0
PYH1_k127_5520214_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 507.0
PYH1_k127_5520214_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 373.0
PYH1_k127_5520214_5 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 304.0
PYH1_k127_5520214_6 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001173 294.0
PYH1_k127_5520214_7 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001406 274.0
PYH1_k127_5520214_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008548 247.0
PYH1_k127_5520214_9 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000003928 252.0
PYH1_k127_5571866_0 DEAD/H associated K03724 - - 0.0 1595.0
PYH1_k127_5571866_1 Domain of unknown function (DUF5117) - - - 2.896e-310 972.0
PYH1_k127_5571866_10 - - - - 0.0000007102 58.0
PYH1_k127_5571866_2 efflux transmembrane transporter activity - - - 2.881e-232 745.0
PYH1_k127_5571866_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 1.198e-200 652.0
PYH1_k127_5571866_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002041 274.0
PYH1_k127_5571866_5 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
PYH1_k127_5571866_6 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000105 243.0
PYH1_k127_5571866_7 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000008229 149.0
PYH1_k127_5571866_8 - - - - 0.00000000000000000000000000000001021 143.0
PYH1_k127_5571866_9 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000002309 96.0
PYH1_k127_5601611_0 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000724 224.0
PYH1_k127_5601611_1 - - - - 0.000000000000006625 79.0
PYH1_k127_5652960_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.733e-231 748.0
PYH1_k127_5652960_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.794e-220 692.0
PYH1_k127_5652960_10 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005274 261.0
PYH1_k127_5652960_11 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000005383 196.0
PYH1_k127_5652960_12 PFAM beta-lactamase domain protein K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000007958 188.0
PYH1_k127_5652960_13 PIN domain - - - 0.0000000000000000000000000000000000000000000005779 171.0
PYH1_k127_5652960_14 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000005954 159.0
PYH1_k127_5652960_15 acetyltransferase - - - 0.00000000000000000000000002123 119.0
PYH1_k127_5652960_16 Protein of unknown function (DUF2892) - - - 0.000000000000000000007215 96.0
PYH1_k127_5652960_17 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000002419 61.0
PYH1_k127_5652960_19 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00004878 52.0
PYH1_k127_5652960_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 457.0
PYH1_k127_5652960_3 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 453.0
PYH1_k127_5652960_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 425.0
PYH1_k127_5652960_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 363.0
PYH1_k127_5652960_6 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 334.0
PYH1_k127_5652960_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 311.0
PYH1_k127_5652960_8 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 301.0
PYH1_k127_5652960_9 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002352 297.0
PYH1_k127_5731566_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 387.0
PYH1_k127_5731566_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 351.0
PYH1_k127_5731566_2 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001516 293.0
PYH1_k127_5731566_3 response regulator K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
PYH1_k127_5731566_4 recA bacterial DNA recombination protein - - - 0.0000000000000000000000000004134 123.0
PYH1_k127_5822680_0 Sortilin, neurotensin receptor 3, - - - 0.0 1024.0
PYH1_k127_5822680_1 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 3.829e-270 861.0
PYH1_k127_5822680_2 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 2.241e-259 816.0
PYH1_k127_5822680_3 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 487.0
PYH1_k127_5822680_4 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 392.0
PYH1_k127_5822680_5 - K01865 - 5.4.4.1 0.00000000000000000000000001745 114.0
PYH1_k127_5822680_6 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.00000000000006905 81.0
PYH1_k127_5879739_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 591.0
PYH1_k127_5879739_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 554.0
PYH1_k127_5879739_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 514.0
PYH1_k127_5879739_3 peptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007692 486.0
PYH1_k127_5879739_4 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 428.0
PYH1_k127_5879739_5 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000005436 221.0
PYH1_k127_5879739_6 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000208 195.0
PYH1_k127_5879739_7 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000003053 151.0
PYH1_k127_5879739_8 Endoribonuclease L-PSP - - - 0.00000000000000131 83.0
PYH1_k127_5885649_0 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004162 254.0
PYH1_k127_5885649_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003333 250.0
PYH1_k127_5885649_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000005735 55.0
PYH1_k127_5893846_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.134e-195 622.0
PYH1_k127_5893846_1 PFAM peptidase S10 serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 446.0
PYH1_k127_5893846_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 440.0
PYH1_k127_5893846_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 320.0
PYH1_k127_5893846_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000007763 169.0
PYH1_k127_5893846_5 - - - - 0.00000000000000000000000000000000000000000001603 168.0
PYH1_k127_5898757_0 oligopeptide transport K03305 - - 1.333e-213 675.0
PYH1_k127_5898757_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000006719 240.0
PYH1_k127_5898757_3 - - - - 0.0000000000000000000000000000000000000000000000004106 180.0
PYH1_k127_5898757_4 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000002463 184.0
PYH1_k127_5898757_5 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000005328 123.0
PYH1_k127_5898757_6 DsrC like protein K11179 - - 0.00000000000000000000000000002262 120.0
PYH1_k127_5909597_0 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 460.0
PYH1_k127_5909597_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 347.0
PYH1_k127_5909597_2 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005533 263.0
PYH1_k127_5909597_3 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000001829 242.0
PYH1_k127_5909597_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.000000000000000000000000000000000000124 153.0
PYH1_k127_5909597_5 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000003841 148.0
PYH1_k127_5909597_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000007786 109.0
PYH1_k127_5909597_7 AcrB/AcrD/AcrF family K03296 - - 0.000000000002221 76.0
PYH1_k127_5909597_8 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.000000002432 66.0
PYH1_k127_5909597_9 Heavy-metal resistance - - - 0.00000003048 61.0
PYH1_k127_5930631_0 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000498 284.0
PYH1_k127_5930631_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000001325 217.0
PYH1_k127_5930631_2 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000007705 186.0
PYH1_k127_5930631_3 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001181 181.0
PYH1_k127_5983258_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000001909 201.0
PYH1_k127_5983258_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000001659 186.0
PYH1_k127_5983258_2 Belongs to the ompA family K03640 - - 0.00000000000000000000003934 107.0
PYH1_k127_5983258_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000001027 104.0
PYH1_k127_6015071_0 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 480.0
PYH1_k127_6015071_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 466.0
PYH1_k127_6015071_10 Belongs to the aldehyde dehydrogenase family K00138,K18370 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.000000000000000000000001036 109.0
PYH1_k127_6015071_11 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000004853 102.0
PYH1_k127_6015071_12 Polymer-forming cytoskeletal - - - 0.00000000000000001153 88.0
PYH1_k127_6015071_13 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.00000000000006548 75.0
PYH1_k127_6015071_14 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000691 53.0
PYH1_k127_6015071_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 308.0
PYH1_k127_6015071_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001446 253.0
PYH1_k127_6015071_4 lyase activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001934 272.0
PYH1_k127_6015071_5 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006904 274.0
PYH1_k127_6015071_6 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000989 254.0
PYH1_k127_6015071_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
PYH1_k127_6015071_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000007343 199.0
PYH1_k127_6015071_9 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000002026 196.0
PYH1_k127_6027810_0 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 450.0
PYH1_k127_6027810_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 272.0
PYH1_k127_6027810_2 Transcription termination factor nusG - - - 0.0000000000000000000000000000000001351 141.0
PYH1_k127_6027810_3 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000005074 126.0
PYH1_k127_6027810_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000004468 92.0
PYH1_k127_6027810_5 Stress responsive A/B Barrel Domain - - - 0.00008862 53.0
PYH1_k127_6034562_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 409.0
PYH1_k127_6034562_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 396.0
PYH1_k127_6034562_10 WxcM-like, C-terminal K01790 - 5.1.3.13 0.0000000009836 61.0
PYH1_k127_6034562_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 353.0
PYH1_k127_6034562_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
PYH1_k127_6034562_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
PYH1_k127_6034562_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001957 275.0
PYH1_k127_6034562_6 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000004084 240.0
PYH1_k127_6034562_7 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000005436 209.0
PYH1_k127_6034562_8 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.0000000000000000000000000000000000000000000000000000002518 219.0
PYH1_k127_6034562_9 E-Z type HEAT repeats - - - 0.000000000005639 78.0
PYH1_k127_6048074_0 Carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 425.0
PYH1_k127_6048074_1 cellulose binding - - - 0.000000000000000000000000000000000001017 145.0
PYH1_k127_6048651_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 467.0
PYH1_k127_6048651_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 388.0
PYH1_k127_6048651_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 304.0
PYH1_k127_6048651_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0007783 46.0
PYH1_k127_6048872_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.099e-318 996.0
PYH1_k127_6048872_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.171e-262 823.0
PYH1_k127_6048872_10 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 368.0
PYH1_k127_6048872_11 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 347.0
PYH1_k127_6048872_12 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 331.0
PYH1_k127_6048872_13 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 329.0
PYH1_k127_6048872_14 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 286.0
PYH1_k127_6048872_15 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001468 272.0
PYH1_k127_6048872_16 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008854 257.0
PYH1_k127_6048872_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000001513 178.0
PYH1_k127_6048872_18 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000000000104 148.0
PYH1_k127_6048872_19 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000001491 147.0
PYH1_k127_6048872_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.662e-237 744.0
PYH1_k127_6048872_20 diguanylate cyclase - - - 0.000000000000000000000000000000003989 147.0
PYH1_k127_6048872_21 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000004101 128.0
PYH1_k127_6048872_22 succinate dehydrogenase activity K00242,K00246 - - 0.0000000000000002271 83.0
PYH1_k127_6048872_23 Protein of unknown function (DUF2905) - - - 0.000000000002927 68.0
PYH1_k127_6048872_3 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 4.583e-221 699.0
PYH1_k127_6048872_4 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 578.0
PYH1_k127_6048872_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 499.0
PYH1_k127_6048872_6 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 486.0
PYH1_k127_6048872_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 414.0
PYH1_k127_6048872_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 406.0
PYH1_k127_6048872_9 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 358.0
PYH1_k127_6082279_0 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000006308 183.0
PYH1_k127_6082279_1 DEAD DEAH box helicase domain protein K06877 - - 0.00000000000000000000000000000000000000000001765 172.0
PYH1_k127_6082279_2 denitrification pathway - - - 0.00000000000000000000000007357 109.0
PYH1_k127_6082279_3 amine dehydrogenase activity K21449 - - 0.0000000000000000000001998 107.0
PYH1_k127_6096972_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1204.0
PYH1_k127_6096972_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1149.0
PYH1_k127_6096972_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 384.0
PYH1_k127_6096972_11 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 362.0
PYH1_k127_6096972_12 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 359.0
PYH1_k127_6096972_13 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 364.0
PYH1_k127_6096972_14 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 333.0
PYH1_k127_6096972_15 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 329.0
PYH1_k127_6096972_16 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
PYH1_k127_6096972_17 Phosphoesterase, PA-phosphatase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 246.0
PYH1_k127_6096972_18 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000000000000000000000001987 200.0
PYH1_k127_6096972_19 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000001336 203.0
PYH1_k127_6096972_2 copper-translocating P-type ATPase K17686 - 3.6.3.54 4.255e-295 932.0
PYH1_k127_6096972_20 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000009052 186.0
PYH1_k127_6096972_21 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000000000000000000000004039 157.0
PYH1_k127_6096972_22 Hydrogenase maturation protease - - - 0.00000000000000000000000000001643 124.0
PYH1_k127_6096972_23 Plasmid stability protein K21495 - - 0.0000000000002778 72.0
PYH1_k127_6096972_24 - - - - 0.00003745 46.0
PYH1_k127_6096972_3 Enterochelin esterase - - - 2.456e-212 672.0
PYH1_k127_6096972_4 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 580.0
PYH1_k127_6096972_5 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 572.0
PYH1_k127_6096972_6 proline dipeptidase activity K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 507.0
PYH1_k127_6096972_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 475.0
PYH1_k127_6096972_8 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 448.0
PYH1_k127_6096972_9 2 iron, 2 sulfur cluster binding K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 377.0
PYH1_k127_6101871_0 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 4.319e-258 817.0
PYH1_k127_6101871_1 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 485.0
PYH1_k127_6101871_10 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000001822 78.0
PYH1_k127_6101871_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 454.0
PYH1_k127_6101871_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 357.0
PYH1_k127_6101871_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002519 246.0
PYH1_k127_6101871_5 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000009895 190.0
PYH1_k127_6101871_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000002964 143.0
PYH1_k127_6101871_7 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000001839 154.0
PYH1_k127_6101871_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000001691 145.0
PYH1_k127_6101871_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000007758 90.0
PYH1_k127_6120611_0 PFAM BNR Asp-box repeat - - - 3.956e-195 631.0
PYH1_k127_6120611_1 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 476.0
PYH1_k127_6136643_0 ABC transporter, transmembrane K18890 - - 1.041e-196 629.0
PYH1_k127_6136643_1 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 579.0
PYH1_k127_6136643_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 526.0
PYH1_k127_6136643_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000004023 218.0
PYH1_k127_6136643_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000777 154.0
PYH1_k127_6136643_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000001121 98.0
PYH1_k127_6136643_6 3D domain - - - 0.0000000000000009799 86.0
PYH1_k127_6136643_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000002467 70.0
PYH1_k127_6136643_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000001985 59.0
PYH1_k127_6214254_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 452.0
PYH1_k127_6214254_1 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000001044 148.0
PYH1_k127_6226041_0 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 400.0
PYH1_k127_6226041_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004081 231.0
PYH1_k127_6226041_2 transferase activity, transferring glycosyl groups K00713,K03280 - 2.4.1.56 0.000000000000000000000000000000000000000000000001145 192.0
PYH1_k127_6226041_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000002591 179.0
PYH1_k127_6226041_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000001016 168.0
PYH1_k127_6226041_5 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000001567 154.0
PYH1_k127_6226041_6 Methyltransferase domain - - - 0.00000000000000000000006442 104.0
PYH1_k127_6226041_7 Glycosyl transferases group 1 - - - 0.00000000000000101 90.0
PYH1_k127_6226041_8 PFAM Glycosyl transferases group 1 - - - 0.00001029 56.0
PYH1_k127_6226041_9 O-Antigen ligase - - - 0.00007542 55.0
PYH1_k127_6277475_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.102e-216 689.0
PYH1_k127_6277475_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 590.0
PYH1_k127_6277475_2 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 561.0
PYH1_k127_6277475_3 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 529.0
PYH1_k127_6277475_4 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 395.0
PYH1_k127_6277475_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 400.0
PYH1_k127_6277475_6 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000002856 225.0
PYH1_k127_6310299_0 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 399.0
PYH1_k127_6310299_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 380.0
PYH1_k127_6310299_10 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.000001308 61.0
PYH1_k127_6310299_2 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000002929 242.0
PYH1_k127_6310299_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
PYH1_k127_6310299_4 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000001881 213.0
PYH1_k127_6310299_5 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000005378 180.0
PYH1_k127_6310299_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000006284 122.0
PYH1_k127_6310299_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000006787 115.0
PYH1_k127_6310299_8 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000004927 112.0
PYH1_k127_6326598_0 Cystathionine beta-synthase K01697 - 4.2.1.22 2.019e-201 636.0
PYH1_k127_6326598_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 491.0
PYH1_k127_6326598_2 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 318.0
PYH1_k127_6350456_0 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 554.0
PYH1_k127_6350456_1 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 347.0
PYH1_k127_6350456_10 Domain of unknown function (DUF4956) - - - 0.0000000000000002988 91.0
PYH1_k127_6350456_11 STAS domain - - - 0.00001513 57.0
PYH1_k127_6350456_2 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003915 286.0
PYH1_k127_6350456_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009139 280.0
PYH1_k127_6350456_4 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000003086 259.0
PYH1_k127_6350456_5 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000002515 181.0
PYH1_k127_6350456_6 phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000203 184.0
PYH1_k127_6350456_7 Spore coat protein CotH - - - 0.0000000000000000000000000000000000000000001507 175.0
PYH1_k127_6350456_8 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.000000000000000000000000000000004758 145.0
PYH1_k127_6350456_9 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000005656 127.0
PYH1_k127_6432316_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 476.0
PYH1_k127_6495216_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1122.0
PYH1_k127_6495216_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 364.0
PYH1_k127_6495216_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000004369 208.0
PYH1_k127_6512695_0 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 1.166e-201 633.0
PYH1_k127_6512695_1 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 1.058e-196 623.0
PYH1_k127_6512695_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 443.0
PYH1_k127_6512695_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 408.0
PYH1_k127_6512695_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 385.0
PYH1_k127_6512695_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 344.0
PYH1_k127_6512695_6 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000006802 241.0
PYH1_k127_6512695_7 radical SAM domain protein - - - 0.0000000000000000000001755 112.0
PYH1_k127_6512695_9 ubiE/COQ5 methyltransferase family - - - 0.00000004638 66.0
PYH1_k127_6613331_0 Beta-lactamase class C - - - 5.963e-223 707.0
PYH1_k127_666594_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 559.0
PYH1_k127_666594_1 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 512.0
PYH1_k127_666594_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 346.0
PYH1_k127_666594_3 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 345.0
PYH1_k127_666594_4 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005219 246.0
PYH1_k127_666594_5 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000001446 239.0
PYH1_k127_6667765_0 Glutamine synthetase type III K01915 - 6.3.1.2 2.055e-300 938.0
PYH1_k127_6667765_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 545.0
PYH1_k127_6667765_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 403.0
PYH1_k127_6667765_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
PYH1_k127_6667765_4 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001226 285.0
PYH1_k127_6667765_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000006243 156.0
PYH1_k127_6667765_6 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000003816 143.0
PYH1_k127_6667765_7 Sigma-70 region 3 K02405,K03093 - - 0.00000000000002159 81.0
PYH1_k127_6667765_8 - - - - 0.0000003043 59.0
PYH1_k127_6667765_9 Tetratricopeptide repeat - - - 0.00008538 55.0
PYH1_k127_670110_0 metallocarboxypeptidase activity K14054 - - 0.0 1107.0
PYH1_k127_670110_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 553.0
PYH1_k127_670110_10 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000007016 81.0
PYH1_k127_670110_12 - - - - 0.00009613 48.0
PYH1_k127_670110_13 DNA-sulfur modification-associated - - - 0.0004241 53.0
PYH1_k127_670110_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 542.0
PYH1_k127_670110_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 447.0
PYH1_k127_670110_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 349.0
PYH1_k127_670110_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
PYH1_k127_670110_6 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000001283 205.0
PYH1_k127_670110_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000002114 162.0
PYH1_k127_670110_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000217 156.0
PYH1_k127_670110_9 sulfopyruvate decarboxylase, alpha subunit K06034 - 4.1.1.79 0.0000000000000000000008018 104.0
PYH1_k127_6733495_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1386.0
PYH1_k127_6733495_1 Peptidase family M49 - - - 4.297e-197 627.0
PYH1_k127_6733495_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000003822 113.0
PYH1_k127_6760248_0 Ferredoxin - - - 0.0000000000000000000000000000000006004 132.0
PYH1_k127_6760248_1 Integrase, catalytic region - - - 0.00000000000000000000000001054 112.0
PYH1_k127_6760248_2 Predicted membrane protein (DUF2079) - - - 0.000000000105 74.0
PYH1_k127_6760987_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 606.0
PYH1_k127_6760987_1 Thioredoxin domain - - - 0.0000000000000000000000000000000000000002246 155.0
PYH1_k127_6760987_2 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000001134 138.0
PYH1_k127_6760987_3 alkyl hydroperoxide reductase activity - - - 0.0000000000000000000001739 98.0
PYH1_k127_6794988_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 518.0
PYH1_k127_6794988_1 Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000542 174.0
PYH1_k127_6798966_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.6e-233 739.0
PYH1_k127_6798966_1 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 455.0
PYH1_k127_6798966_2 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008992 286.0
PYH1_k127_6798966_3 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000001965 192.0
PYH1_k127_6798966_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000001431 179.0
PYH1_k127_6798966_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000001879 113.0
PYH1_k127_6798966_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00002077 52.0
PYH1_k127_6837673_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.028e-270 843.0
PYH1_k127_6846666_0 RmlD substrate binding domain K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 504.0
PYH1_k127_6846666_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 261.0
PYH1_k127_6846666_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005254 255.0
PYH1_k127_6873037_0 ThiC-associated domain K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 6.735e-275 855.0
PYH1_k127_6873037_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 574.0
PYH1_k127_6873037_2 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 547.0
PYH1_k127_6873037_3 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 368.0
PYH1_k127_6873037_4 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000114 240.0
PYH1_k127_6873037_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000001314 218.0
PYH1_k127_6873037_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000001176 177.0
PYH1_k127_6873037_7 peptidyl-tyrosine sulfation - - - 0.00000000002345 75.0
PYH1_k127_6883745_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 608.0
PYH1_k127_6883745_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000001561 184.0
PYH1_k127_6911985_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1039.0
PYH1_k127_6911985_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.09e-278 879.0
PYH1_k127_6911985_10 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000005286 134.0
PYH1_k127_6911985_11 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000002882 124.0
PYH1_k127_6911985_12 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000001152 125.0
PYH1_k127_6911985_13 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000002948 110.0
PYH1_k127_6911985_14 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000001021 101.0
PYH1_k127_6911985_15 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001012 90.0
PYH1_k127_6911985_16 phosphatase activity K07025 - - 0.00000000000000003172 94.0
PYH1_k127_6911985_17 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000003049 85.0
PYH1_k127_6911985_18 - - - - 0.000000009096 65.0
PYH1_k127_6911985_19 Cytochrome c554 and c-prime - - - 0.0000001359 63.0
PYH1_k127_6911985_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.659e-243 770.0
PYH1_k127_6911985_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 351.0
PYH1_k127_6911985_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 316.0
PYH1_k127_6911985_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001801 287.0
PYH1_k127_6911985_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002951 258.0
PYH1_k127_6911985_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000003131 220.0
PYH1_k127_6911985_8 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000112 192.0
PYH1_k127_6911985_9 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000008851 162.0
PYH1_k127_6918505_0 cellulose binding - - - 4.394e-239 754.0
PYH1_k127_6918505_1 COG1012 NAD-dependent aldehyde dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 478.0
PYH1_k127_6918505_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 450.0
PYH1_k127_6927239_0 ADP-glyceromanno-heptose 6-epimerase activity K01784,K12454 - 5.1.3.10,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 511.0
PYH1_k127_6927239_1 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 430.0
PYH1_k127_6927239_10 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000007953 133.0
PYH1_k127_6927239_11 CobQ CobB MinD ParA nucleotide binding domain - - - 0.000002399 59.0
PYH1_k127_6927239_12 O-Antigen ligase - - - 0.0004972 52.0
PYH1_k127_6927239_2 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 308.0
PYH1_k127_6927239_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002679 249.0
PYH1_k127_6927239_4 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008107 237.0
PYH1_k127_6927239_5 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000004622 188.0
PYH1_k127_6927239_6 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000002926 185.0
PYH1_k127_6927239_7 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.000000000000000000000000000000000000003349 163.0
PYH1_k127_6927239_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000006129 148.0
PYH1_k127_6927239_9 Chain length determinant protein - - - 0.00000000000000000000000000000000004342 153.0
PYH1_k127_6927689_0 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 337.0
PYH1_k127_6927689_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000362 262.0
PYH1_k127_6927689_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000003722 110.0
PYH1_k127_6927689_3 Hydrogenase nickel incorporation protein hypA K04651 - - 0.00000000000000000007057 93.0
PYH1_k127_6934824_0 FtsX-like permease family K02004 - - 1.673e-232 745.0
PYH1_k127_6934824_1 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 344.0
PYH1_k127_6934824_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003516 211.0
PYH1_k127_6934824_3 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000009472 135.0
PYH1_k127_6934824_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000008143 96.0
PYH1_k127_6934824_5 PFAM Glycosyl transferases group 1 - - - 0.0000000000009605 81.0
PYH1_k127_7015443_0 Domain of unknown function (DUF4976) - - - 5.396e-250 779.0
PYH1_k127_7015443_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 488.0
PYH1_k127_7015443_10 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 257.0
PYH1_k127_7015443_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000001384 261.0
PYH1_k127_7015443_12 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
PYH1_k127_7015443_13 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000001387 161.0
PYH1_k127_7015443_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000004771 143.0
PYH1_k127_7015443_15 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000003052 147.0
PYH1_k127_7015443_16 Tetratricopeptide repeat - - - 0.000000000000000003972 98.0
PYH1_k127_7015443_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 417.0
PYH1_k127_7015443_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 398.0
PYH1_k127_7015443_4 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 350.0
PYH1_k127_7015443_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 349.0
PYH1_k127_7015443_6 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 339.0
PYH1_k127_7015443_7 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007819 298.0
PYH1_k127_7015443_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003744 281.0
PYH1_k127_7015443_9 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006834 288.0
PYH1_k127_7055868_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 1.325e-300 955.0
PYH1_k127_7055868_1 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
PYH1_k127_7055868_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 316.0
PYH1_k127_7055868_3 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000001102 235.0
PYH1_k127_7055868_4 response to heat K03668,K06079,K09914 - - 0.00000000000000000000004019 110.0
PYH1_k127_7055868_5 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.000000000000000008195 96.0
PYH1_k127_7055868_6 PFAM Tetratricopeptide repeat - - - 0.0000001012 65.0
PYH1_k127_7055868_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.00005706 49.0
PYH1_k127_7061837_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 387.0
PYH1_k127_7061837_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 374.0
PYH1_k127_7061837_2 ATP:ADP antiporter activity K01932,K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 308.0
PYH1_k127_7064543_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000001569 161.0
PYH1_k127_7064543_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000005111 62.0
PYH1_k127_7071683_0 Zinc carboxypeptidase - - - 0.0 1336.0
PYH1_k127_7071683_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 557.0
PYH1_k127_7071683_2 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 355.0
PYH1_k127_7071683_3 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000288 179.0
PYH1_k127_7071683_4 Periplasmic or secreted lipoprotein - - - 0.00000000000000000001953 104.0
PYH1_k127_7103447_0 enterobactin catabolic process - - - 7.093e-198 633.0
PYH1_k127_7103447_1 nuclear chromosome segregation - - - 1.753e-197 658.0
PYH1_k127_7103447_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000001409 215.0
PYH1_k127_7103447_3 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000004321 207.0
PYH1_k127_7103447_4 oxidoreductase activity - - - 0.000000000000000000000000000000777 138.0
PYH1_k127_7103447_5 Protein of unknown function (DUF454) K09790 - - 0.0000000001048 70.0
PYH1_k127_7159793_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 557.0
PYH1_k127_7159793_1 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 283.0
PYH1_k127_723066_0 serine-type peptidase activity K01278 - 3.4.14.5 5.507e-229 732.0
PYH1_k127_723066_1 Oligopeptidase F K08602 - - 2.449e-198 638.0
PYH1_k127_723066_2 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 376.0
PYH1_k127_723066_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
PYH1_k127_723066_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001721 198.0
PYH1_k127_723066_5 nuclear chromosome segregation K09971,K21449 - - 0.000000514 60.0
PYH1_k127_723066_6 - - - - 0.00000121 56.0
PYH1_k127_7242774_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1729.0
PYH1_k127_7242774_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 514.0
PYH1_k127_7242774_10 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
PYH1_k127_7242774_11 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004559 272.0
PYH1_k127_7242774_12 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000644 187.0
PYH1_k127_7242774_13 OsmC-like protein - - - 0.000000000000000000000000000000004646 133.0
PYH1_k127_7242774_14 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000000000001422 123.0
PYH1_k127_7242774_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000005529 114.0
PYH1_k127_7242774_16 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.0000000000000000000001126 110.0
PYH1_k127_7242774_17 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000128 100.0
PYH1_k127_7242774_18 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000005547 91.0
PYH1_k127_7242774_19 - - - - 0.000000000000002952 88.0
PYH1_k127_7242774_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 498.0
PYH1_k127_7242774_20 CAAX protease self-immunity K07052 - - 0.0000003857 61.0
PYH1_k127_7242774_21 - - - - 0.0000005165 60.0
PYH1_k127_7242774_23 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000005261 53.0
PYH1_k127_7242774_24 inositol 2-dehydrogenase activity - - - 0.00005305 49.0
PYH1_k127_7242774_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 461.0
PYH1_k127_7242774_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 434.0
PYH1_k127_7242774_5 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 428.0
PYH1_k127_7242774_6 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 429.0
PYH1_k127_7242774_7 cobalamin-transporting ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 394.0
PYH1_k127_7242774_8 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 322.0
PYH1_k127_7242774_9 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 315.0
PYH1_k127_7250125_0 glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich K01190 - 3.2.1.23 4.927e-318 1019.0
PYH1_k127_7250125_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001329 269.0
PYH1_k127_7250125_2 Tetratricopeptide repeat - - - 0.000000000000000000001198 100.0
PYH1_k127_7250125_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000001208 93.0
PYH1_k127_7254221_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 370.0
PYH1_k127_7254221_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 321.0
PYH1_k127_7254221_2 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000006647 125.0
PYH1_k127_7255261_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 503.0
PYH1_k127_7255261_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 301.0
PYH1_k127_7255261_2 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000001181 229.0
PYH1_k127_7255261_3 PIN domain - - - 0.00000000000000000000000001196 113.0
PYH1_k127_7255261_4 Transposase - - - 0.0001912 50.0
PYH1_k127_7266755_0 Beta-L-arabinofuranosidase, GH127 - - - 3.703e-239 757.0
PYH1_k127_7266755_1 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 323.0
PYH1_k127_7266755_2 PIN domain K18828 - - 0.000000000000000000000000000000004157 134.0
PYH1_k127_7266755_3 PFAM Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000131 117.0
PYH1_k127_7266755_4 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000001303 103.0
PYH1_k127_7266755_5 - - - - 0.00000000000003265 76.0
PYH1_k127_7266755_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000002605 78.0
PYH1_k127_7266755_7 - - - - 0.0000000002147 66.0
PYH1_k127_7266755_8 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0004362 43.0
PYH1_k127_7282562_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.327e-197 623.0
PYH1_k127_7282562_1 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000003797 175.0
PYH1_k127_7294183_0 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 484.0
PYH1_k127_7294183_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 465.0
PYH1_k127_7294183_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484 - 2.7.13.3 0.000000000000000000000000000000266 124.0
PYH1_k127_7294183_11 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000004153 111.0
PYH1_k127_7294183_12 CHAD domain containing protein - - - 0.000000004329 68.0
PYH1_k127_7294183_13 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0008264 43.0
PYH1_k127_7294183_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 462.0
PYH1_k127_7294183_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 442.0
PYH1_k127_7294183_4 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 406.0
PYH1_k127_7294183_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 398.0
PYH1_k127_7294183_6 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002168 276.0
PYH1_k127_7294183_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000004733 238.0
PYH1_k127_7294183_8 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000053 240.0
PYH1_k127_7294183_9 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000001055 199.0
PYH1_k127_730267_0 Dienelactone hydrolase family - - - 4.163e-231 739.0
PYH1_k127_730267_1 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 543.0
PYH1_k127_730267_10 DinB superfamily - - - 0.00000000000000000000000000000000000000000000001142 188.0
PYH1_k127_730267_11 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000003166 170.0
PYH1_k127_730267_12 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.0000000000000000001469 96.0
PYH1_k127_730267_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 525.0
PYH1_k127_730267_3 protease-associated PA domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 490.0
PYH1_k127_730267_4 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 402.0
PYH1_k127_730267_5 Surface antigen K07277,K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 430.0
PYH1_k127_730267_6 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 382.0
PYH1_k127_730267_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 378.0
PYH1_k127_730267_8 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 386.0
PYH1_k127_730267_9 Substrate binding domain of ABC-type glycine betaine transport system K05772 - - 0.00000000000000000000000000000000000000000000000004668 189.0
PYH1_k127_7343003_0 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 348.0
PYH1_k127_7343003_1 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 300.0
PYH1_k127_7343003_3 Pfam:UPF0118 - - - 0.00000000000000000000000000000005581 130.0
PYH1_k127_7343003_4 - - - - 0.0000000000005302 79.0
PYH1_k127_7369223_0 G-rich domain on putative tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 369.0
PYH1_k127_7369223_1 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 314.0
PYH1_k127_7369223_10 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000000006322 82.0
PYH1_k127_7369223_11 Transglutaminase-like superfamily - - - 0.00003361 53.0
PYH1_k127_7369223_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 308.0
PYH1_k127_7369223_3 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 312.0
PYH1_k127_7369223_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000001754 184.0
PYH1_k127_7369223_5 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.000000000000000000000000000000000000000000000007267 187.0
PYH1_k127_7369223_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000006842 160.0
PYH1_k127_7369223_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000003991 98.0
PYH1_k127_7369223_8 Methyltransferase small domain - - - 0.00000000000000003413 94.0
PYH1_k127_7369223_9 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000007556 78.0
PYH1_k127_7427884_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1234.0
PYH1_k127_7427884_1 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 564.0
PYH1_k127_7427884_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000001307 61.0
PYH1_k127_7427884_2 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 511.0
PYH1_k127_7427884_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001 261.0
PYH1_k127_7427884_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009083 274.0
PYH1_k127_7427884_5 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000002225 260.0
PYH1_k127_7427884_6 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001282 247.0
PYH1_k127_7427884_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002759 221.0
PYH1_k127_7427884_8 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000004781 149.0
PYH1_k127_7427884_9 Biotin-requiring enzyme - - - 0.0000000000000000000005496 103.0
PYH1_k127_7435830_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 456.0
PYH1_k127_7435830_1 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 430.0
PYH1_k127_7435830_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000003222 91.0
PYH1_k127_7463708_0 Sortilin, neurotensin receptor 3, - - - 5.931e-302 958.0
PYH1_k127_7463708_1 Cytochrome c-type biogenesis protein K02198 - - 3.224e-236 749.0
PYH1_k127_7463708_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000005932 89.0
PYH1_k127_7463708_12 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000009057 82.0
PYH1_k127_7463708_13 - - - - 0.0000000000005721 79.0
PYH1_k127_7463708_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.00012 49.0
PYH1_k127_7463708_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 507.0
PYH1_k127_7463708_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 490.0
PYH1_k127_7463708_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 359.0
PYH1_k127_7463708_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000257 221.0
PYH1_k127_7463708_6 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000002147 198.0
PYH1_k127_7463708_7 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000001327 197.0
PYH1_k127_7463708_8 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000403 189.0
PYH1_k127_7463708_9 23S rRNA-intervening sequence protein - - - 0.00000000000000000002131 96.0
PYH1_k127_7498167_0 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001614 286.0
PYH1_k127_7498167_1 Hydrogenase maturation protease K03605 - - 0.0002177 51.0
PYH1_k127_7553883_0 radical SAM domain protein K22318 - - 2.575e-240 754.0
PYH1_k127_7553883_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 9.635e-208 656.0
PYH1_k127_7553883_10 Protein of unknown function (DUF2892) - - - 0.0000008475 53.0
PYH1_k127_7553883_11 Putative zinc-finger - - - 0.0003156 48.0
PYH1_k127_7553883_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 405.0
PYH1_k127_7553883_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 371.0
PYH1_k127_7553883_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 323.0
PYH1_k127_7553883_5 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000007345 229.0
PYH1_k127_7553883_6 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000002864 199.0
PYH1_k127_7553883_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000002413 124.0
PYH1_k127_7553883_8 hemerythrin HHE cation binding domain - - - 0.0000000000000000000839 96.0
PYH1_k127_7553883_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000001576 66.0
PYH1_k127_7582534_0 Belongs to the carbamoyltransferase HypF family K04656 - - 5.032e-284 899.0
PYH1_k127_7582534_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 586.0
PYH1_k127_7582534_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 346.0
PYH1_k127_7582534_3 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000005415 249.0
PYH1_k127_7582534_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000803 168.0
PYH1_k127_7582534_5 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000000001483 119.0
PYH1_k127_7582534_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000005942 97.0
PYH1_k127_7610138_0 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 281.0
PYH1_k127_7610138_1 Protein of unknown function (DUF1345) - - - 0.0000000000000000000000000000000000000000000002489 175.0
PYH1_k127_7612529_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.724e-301 933.0
PYH1_k127_7626083_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 503.0
PYH1_k127_7626083_1 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000753 201.0
PYH1_k127_7626083_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000002471 141.0
PYH1_k127_7626083_3 Nucleotidyltransferase domain - - - 0.00002639 50.0
PYH1_k127_7637170_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 443.0
PYH1_k127_7637170_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000656 138.0
PYH1_k127_7648070_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 443.0
PYH1_k127_7648070_1 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000000001154 238.0
PYH1_k127_7648070_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000001659 203.0
PYH1_k127_7648070_3 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.0000000000000000000000000000000000000000000000002579 182.0
PYH1_k127_7648070_4 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000001286 128.0
PYH1_k127_7661505_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1116.0
PYH1_k127_7661505_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 1.655e-267 852.0
PYH1_k127_7661505_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008528 144.0
PYH1_k127_7661505_11 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000221 58.0
PYH1_k127_7661505_2 FMN binding - - - 9.482e-248 775.0
PYH1_k127_7661505_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.98e-233 734.0
PYH1_k127_7661505_4 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 8.464e-221 691.0
PYH1_k127_7661505_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 565.0
PYH1_k127_7661505_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 451.0
PYH1_k127_7661505_7 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001682 285.0
PYH1_k127_7661505_8 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000003744 207.0
PYH1_k127_7661505_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000007064 183.0
PYH1_k127_7674882_0 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000002842 241.0
PYH1_k127_7674882_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000001811 165.0
PYH1_k127_7674882_2 - - - - 0.0000001454 56.0
PYH1_k127_7691387_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 499.0
PYH1_k127_7691387_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 470.0
PYH1_k127_7691387_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 332.0
PYH1_k127_7691387_3 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
PYH1_k127_7691387_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000198 137.0
PYH1_k127_7691387_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000009503 94.0
PYH1_k127_7693225_0 Aldo/keto reductase family K00002 - 1.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
PYH1_k127_7693225_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000004685 216.0
PYH1_k127_7693225_2 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000006105 155.0
PYH1_k127_7696818_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 397.0
PYH1_k127_7696818_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000005376 163.0
PYH1_k127_7696818_2 multi-organism process - - - 0.00000000009201 72.0
PYH1_k127_7710538_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 322.0
PYH1_k127_7710538_1 Protein of unknown function (DUF3810) - - - 0.00000000000000007952 92.0
PYH1_k127_7727058_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.276e-270 850.0
PYH1_k127_7727058_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.915e-236 745.0
PYH1_k127_7727058_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 339.0
PYH1_k127_7727058_3 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000108 262.0
PYH1_k127_7727058_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000501 243.0
PYH1_k127_7727058_5 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000001358 226.0
PYH1_k127_7727058_6 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004828 136.0
PYH1_k127_7727058_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000002864 115.0
PYH1_k127_7727058_8 Protein of unknown function (DUF503) K09764 - - 0.00000000000000003386 84.0
PYH1_k127_7727058_9 nitrous oxide reductase K00376 - 1.7.2.4 0.0000000002483 68.0
PYH1_k127_7728078_0 efflux protein, MATE family K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 445.0
PYH1_k127_7728078_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 384.0
PYH1_k127_7728078_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 313.0
PYH1_k127_7728078_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 289.0
PYH1_k127_7728078_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000008879 179.0
PYH1_k127_7728078_5 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000005404 145.0
PYH1_k127_7728078_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000582 64.0
PYH1_k127_7747786_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 450.0
PYH1_k127_7747786_1 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 389.0
PYH1_k127_7747786_2 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 378.0
PYH1_k127_7747786_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 337.0
PYH1_k127_7747786_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 313.0
PYH1_k127_7747786_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000693 286.0
PYH1_k127_7747786_6 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000002975 225.0
PYH1_k127_7747786_7 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000003886 180.0
PYH1_k127_7747786_8 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000004031 164.0
PYH1_k127_7747786_9 Involved in the tonB-independent uptake of proteins - GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575 - 0.000000000000000000000000000000001512 141.0
PYH1_k127_7754929_0 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 297.0
PYH1_k127_7754929_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001809 259.0
PYH1_k127_7754929_2 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000000005395 229.0
PYH1_k127_7754929_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000000000000000003127 216.0
PYH1_k127_7754929_4 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000005561 140.0
PYH1_k127_7754929_5 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000003587 115.0
PYH1_k127_7754929_6 - - - - 0.0000000000000000004855 87.0
PYH1_k127_7754929_7 Uracil-DNA glycosylase - - - 0.00001639 54.0
PYH1_k127_7757795_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 493.0
PYH1_k127_7757795_1 RibD C-terminal domain - - - 0.000000000000000000353 88.0
PYH1_k127_7770887_0 serine-type peptidase activity - - - 0.0 1159.0
PYH1_k127_7770887_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 574.0
PYH1_k127_7770887_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 489.0
PYH1_k127_7770887_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
PYH1_k127_7770887_4 - K06921 - - 0.00000000000000000000000000000000000000000000000000000000000001549 229.0
PYH1_k127_7770887_5 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000003646 202.0
PYH1_k127_7770887_6 23S rRNA-intervening sequence protein - - - 0.00000000000000000002044 104.0
PYH1_k127_7770887_7 - - - - 0.000000000000008255 85.0
PYH1_k127_7834700_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 3.804e-312 973.0
PYH1_k127_7834700_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.459e-265 831.0
PYH1_k127_7834700_10 serine-type D-Ala-D-Ala carboxypeptidase activity K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 313.0
PYH1_k127_7834700_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
PYH1_k127_7834700_12 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005953 270.0
PYH1_k127_7834700_13 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000005674 276.0
PYH1_k127_7834700_14 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 274.0
PYH1_k127_7834700_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000005231 276.0
PYH1_k127_7834700_16 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 265.0
PYH1_k127_7834700_17 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004116 256.0
PYH1_k127_7834700_18 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000139 262.0
PYH1_k127_7834700_19 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000002698 253.0
PYH1_k127_7834700_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 451.0
PYH1_k127_7834700_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000405 206.0
PYH1_k127_7834700_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000203 199.0
PYH1_k127_7834700_22 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000003372 148.0
PYH1_k127_7834700_23 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000000000388 125.0
PYH1_k127_7834700_24 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000002761 121.0
PYH1_k127_7834700_25 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000176 129.0
PYH1_k127_7834700_26 PFAM regulatory protein ArsR K21903 - - 0.000000000000000000000000002437 116.0
PYH1_k127_7834700_27 Tetratricopeptide repeat - - - 0.00000000000000000000000003384 116.0
PYH1_k127_7834700_28 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000002253 100.0
PYH1_k127_7834700_29 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000004797 79.0
PYH1_k127_7834700_3 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 405.0
PYH1_k127_7834700_30 PFAM YbbR family protein - - - 0.0000000003686 71.0
PYH1_k127_7834700_31 ArsC family K00537 - 1.20.4.1 0.000000003675 61.0
PYH1_k127_7834700_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 410.0
PYH1_k127_7834700_5 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 375.0
PYH1_k127_7834700_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 345.0
PYH1_k127_7834700_7 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 339.0
PYH1_k127_7834700_8 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 347.0
PYH1_k127_7834700_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 305.0
PYH1_k127_7844554_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 472.0
PYH1_k127_7844554_1 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 367.0
PYH1_k127_7844554_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 336.0
PYH1_k127_7844554_3 Putative esterase K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003715 276.0
PYH1_k127_7844554_4 PFAM CoA-binding domain protein K06929 - - 0.0000000000000008313 79.0
PYH1_k127_7856874_0 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000001631 148.0
PYH1_k127_7856874_1 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000002749 127.0
PYH1_k127_7856874_2 nucleotidyltransferase activity - - - 0.000000000000000000001141 99.0
PYH1_k127_7856874_3 repeat protein - - - 0.00000000000001627 83.0
PYH1_k127_7856874_4 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000000000001284 80.0
PYH1_k127_7888927_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 9.171e-228 715.0
PYH1_k127_7888927_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 454.0
PYH1_k127_7888927_10 Mo-molybdopterin cofactor metabolic process K03636,K03637,K03752,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12,4.6.1.17 0.00000000000006154 80.0
PYH1_k127_7888927_11 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00007302 46.0
PYH1_k127_7888927_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001953 283.0
PYH1_k127_7888927_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000001763 222.0
PYH1_k127_7888927_4 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000001926 173.0
PYH1_k127_7888927_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000007172 171.0
PYH1_k127_7888927_6 PFAM BioY protein K03523 - - 0.00000000000000000000000000000000000005741 160.0
PYH1_k127_7888927_7 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000004523 146.0
PYH1_k127_7888927_8 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000005569 134.0
PYH1_k127_7888927_9 Belongs to the Fur family K03711 - - 0.00000000000000000001424 104.0
PYH1_k127_7902473_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.402e-286 897.0
PYH1_k127_7902473_1 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 5.379e-240 754.0
PYH1_k127_7902473_10 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000002315 209.0
PYH1_k127_7902473_11 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000003414 179.0
PYH1_k127_7902473_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000001266 170.0
PYH1_k127_7902473_13 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000008321 152.0
PYH1_k127_7902473_14 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000005423 152.0
PYH1_k127_7902473_15 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000009844 142.0
PYH1_k127_7902473_16 YqeY-like protein K09117 - - 0.00000000000000000000000000003354 122.0
PYH1_k127_7902473_17 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000003172 119.0
PYH1_k127_7902473_18 TQO small subunit DoxD K16937 - 1.8.5.2 0.000003766 56.0
PYH1_k127_7902473_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 460.0
PYH1_k127_7902473_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 436.0
PYH1_k127_7902473_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 409.0
PYH1_k127_7902473_5 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 340.0
PYH1_k127_7902473_6 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 343.0
PYH1_k127_7902473_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 310.0
PYH1_k127_7902473_8 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000001044 241.0
PYH1_k127_7902473_9 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000751 244.0
PYH1_k127_7943178_0 Prolyl oligopeptidase family - - - 9.676e-245 768.0
PYH1_k127_7943178_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000003538 248.0
PYH1_k127_7943178_2 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000001056 214.0
PYH1_k127_7943178_3 HNH nucleases - - - 0.00000000000000000000000000000000417 135.0
PYH1_k127_7943178_4 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000001066 139.0
PYH1_k127_7943178_5 Receptor - - - 0.00000002829 63.0
PYH1_k127_7943178_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001032 45.0
PYH1_k127_7966958_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 3.347e-198 647.0
PYH1_k127_7966958_1 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 473.0
PYH1_k127_7966958_11 WHG domain - - - 0.0000000000000000000001207 108.0
PYH1_k127_7966958_12 efflux transmembrane transporter activity - - - 0.0000000000000000005523 100.0
PYH1_k127_7966958_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 463.0
PYH1_k127_7966958_3 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005075 288.0
PYH1_k127_7966958_4 Alanine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001098 267.0
PYH1_k127_7966958_5 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000000000000000000001258 201.0
PYH1_k127_7966958_6 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000006501 196.0
PYH1_k127_7966958_7 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000447 193.0
PYH1_k127_7966958_8 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000261 169.0
PYH1_k127_7966958_9 BMC domain - - - 0.000000000000000000000000000009062 120.0
PYH1_k127_7973402_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 463.0
PYH1_k127_7973402_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 394.0
PYH1_k127_7973402_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000008236 209.0
PYH1_k127_7973402_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000008353 194.0
PYH1_k127_7973402_12 OmpA family K03640 - - 0.000000000000000000000000000000000001044 142.0
PYH1_k127_7973402_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000002966 133.0
PYH1_k127_7973402_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000001784 102.0
PYH1_k127_7973402_15 PFAM glutaredoxin 2 - - - 0.00000000000008796 77.0
PYH1_k127_7973402_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 342.0
PYH1_k127_7973402_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000302 258.0
PYH1_k127_7973402_4 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001471 258.0
PYH1_k127_7973402_5 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007855 264.0
PYH1_k127_7973402_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001825 253.0
PYH1_k127_7973402_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001631 234.0
PYH1_k127_7973402_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
PYH1_k127_7973402_9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000003115 219.0
PYH1_k127_8041581_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 525.0
PYH1_k127_8041581_1 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 370.0
PYH1_k127_8041581_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002176 284.0
PYH1_k127_8041581_3 Replicative DNA helicase K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000009286 234.0
PYH1_k127_8041581_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000002875 173.0
PYH1_k127_8041581_5 B3/4 domain - - - 0.00000000000000000000000000003972 132.0
PYH1_k127_8046963_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2036.0
PYH1_k127_8052589_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.645e-243 781.0
PYH1_k127_8052589_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.022e-205 661.0
PYH1_k127_8052589_10 Coenzyme A transferase K01027,K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 332.0
PYH1_k127_8052589_11 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 318.0
PYH1_k127_8052589_12 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 302.0
PYH1_k127_8052589_13 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000001442 279.0
PYH1_k127_8052589_14 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000004211 255.0
PYH1_k127_8052589_15 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004088 263.0
PYH1_k127_8052589_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
PYH1_k127_8052589_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000007424 234.0
PYH1_k127_8052589_18 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000004317 212.0
PYH1_k127_8052589_19 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000002292 219.0
PYH1_k127_8052589_2 Ftsk_gamma K03466 - - 1.843e-197 640.0
PYH1_k127_8052589_20 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000232 207.0
PYH1_k127_8052589_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000004842 181.0
PYH1_k127_8052589_22 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000004242 140.0
PYH1_k127_8052589_23 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000001697 131.0
PYH1_k127_8052589_24 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000003016 118.0
PYH1_k127_8052589_25 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000049 110.0
PYH1_k127_8052589_26 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000001857 93.0
PYH1_k127_8052589_27 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00001189 55.0
PYH1_k127_8052589_28 Domain of unknown function (DUF4349) - - - 0.0001043 53.0
PYH1_k127_8052589_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 545.0
PYH1_k127_8052589_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 516.0
PYH1_k127_8052589_5 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 509.0
PYH1_k127_8052589_6 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 490.0
PYH1_k127_8052589_7 Short chain fatty K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 464.0
PYH1_k127_8052589_8 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 454.0
PYH1_k127_8052589_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 396.0
PYH1_k127_8055797_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 314.0
PYH1_k127_8055797_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000004713 194.0
PYH1_k127_8076558_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 591.0
PYH1_k127_8076558_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 516.0
PYH1_k127_8076558_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 302.0
PYH1_k127_8076558_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000006411 199.0
PYH1_k127_8076558_4 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000008031 211.0
PYH1_k127_8076558_5 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000000000000000000000000001271 207.0
PYH1_k127_8076558_6 PAP2 superfamily - - - 0.00000000000000000000000000000000001749 144.0
PYH1_k127_8076558_7 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000005648 136.0
PYH1_k127_8076558_8 - - - - 0.000001581 60.0
PYH1_k127_8076558_9 PIN domain K07063 - - 0.0004293 46.0
PYH1_k127_8083870_0 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000004135 258.0
PYH1_k127_8083870_1 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000019 166.0
PYH1_k127_8097577_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1267.0
PYH1_k127_8097577_1 xanthine dehydrogenase activity - - - 1.662e-310 965.0
PYH1_k127_8097577_10 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000001862 200.0
PYH1_k127_8097577_12 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000008297 135.0
PYH1_k127_8097577_13 - - - - 0.00000000000000000016 102.0
PYH1_k127_8097577_15 dihydroorotate dehydrogenase activity - - - 0.00000002049 61.0
PYH1_k127_8097577_2 Pyridoxal-phosphate dependent enzyme - - - 1.132e-207 657.0
PYH1_k127_8097577_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 479.0
PYH1_k127_8097577_4 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 473.0
PYH1_k127_8097577_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
PYH1_k127_8097577_6 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 400.0
PYH1_k127_8097577_7 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 382.0
PYH1_k127_8097577_8 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 355.0
PYH1_k127_8097577_9 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005436 275.0
PYH1_k127_8120308_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1073.0
PYH1_k127_8120308_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.039e-199 640.0
PYH1_k127_8120308_10 Phospholipid N-methyltransferase - - - 0.000000000000000000000000000000000003978 144.0
PYH1_k127_8120308_11 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000008396 134.0
PYH1_k127_8120308_2 Histidine kinase internal region K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 329.0
PYH1_k127_8120308_3 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007774 263.0
PYH1_k127_8120308_4 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000006081 243.0
PYH1_k127_8120308_5 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000002375 247.0
PYH1_k127_8120308_6 - - - - 0.000000000000000000000000000000000000000000000000002884 188.0
PYH1_k127_8120308_7 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000001624 184.0
PYH1_k127_8120308_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000001961 178.0
PYH1_k127_8120308_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000008137 159.0
PYH1_k127_8288872_0 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 539.0
PYH1_k127_8288872_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 343.0
PYH1_k127_8288872_2 Protein of unknown function (DUF1177) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008825 237.0
PYH1_k127_8288872_3 YCII-related domain K09780 - - 0.0000000000000000000000000000000000000008838 149.0
PYH1_k127_8288872_4 AroM protein K14591 - - 0.00000000000001852 83.0
PYH1_k127_829_0 Urocanase C-terminal domain K01712 - 4.2.1.49 4.121e-263 821.0
PYH1_k127_829_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 492.0
PYH1_k127_829_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 424.0
PYH1_k127_829_3 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 317.0
PYH1_k127_829_4 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001352 282.0
PYH1_k127_829_5 COG0006 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001059 268.0
PYH1_k127_829_6 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000009548 222.0
PYH1_k127_829_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000003559 209.0
PYH1_k127_829_8 - - - - 0.00000001538 65.0
PYH1_k127_829_9 AAA ATPase domain - - - 0.00000005053 65.0
PYH1_k127_8335218_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 7.741e-226 720.0
PYH1_k127_8335218_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 559.0
PYH1_k127_8335218_10 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000000000000000005478 216.0
PYH1_k127_8335218_11 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000002165 156.0
PYH1_k127_8335218_12 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000005214 150.0
PYH1_k127_8335218_13 Tetratricopeptide repeat - - - 0.00000000000000000002721 104.0
PYH1_k127_8335218_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 413.0
PYH1_k127_8335218_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 319.0
PYH1_k127_8335218_4 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 312.0
PYH1_k127_8335218_5 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002764 280.0
PYH1_k127_8335218_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000001502 252.0
PYH1_k127_8335218_7 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000002499 254.0
PYH1_k127_8335218_8 COG3938 Proline racemase K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000003148 240.0
PYH1_k127_8335218_9 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000000000007804 222.0
PYH1_k127_8354331_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 7.512e-204 659.0
PYH1_k127_8354331_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
PYH1_k127_8354331_2 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000003839 218.0
PYH1_k127_8354331_3 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000002197 220.0
PYH1_k127_8354331_4 beta-lactamase - - - 0.00000003286 61.0
PYH1_k127_8354331_5 Lipid A oxidase K12980 - - 0.0000006672 60.0
PYH1_k127_861515_0 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 395.0
PYH1_k127_861515_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000002985 158.0
PYH1_k127_924721_0 Amidohydrolase family - - - 2.787e-239 752.0
PYH1_k127_924721_1 Amidohydrolase family - - - 3.462e-226 717.0
PYH1_k127_924721_10 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000004842 206.0
PYH1_k127_924721_11 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000000000000000000000008516 177.0
PYH1_k127_924721_12 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000516 164.0
PYH1_k127_924721_13 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000521 103.0
PYH1_k127_924721_14 Putative beta-barrel porin 2 K20920 - - 0.00008517 55.0
PYH1_k127_924721_2 Belongs to the aldehyde dehydrogenase family K00130,K00135,K09472,K22187 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99 7.473e-207 655.0
PYH1_k127_924721_3 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 564.0
PYH1_k127_924721_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 411.0
PYH1_k127_924721_5 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 381.0
PYH1_k127_924721_6 alcohol dehydrogenase K00001,K00004,K00098 - 1.1.1.1,1.1.1.264,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 311.0
PYH1_k127_924721_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 289.0
PYH1_k127_924721_8 Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs K05544 - 1.3.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000002239 262.0
PYH1_k127_924721_9 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000002058 224.0
PYH1_k127_941658_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001134 259.0
PYH1_k127_941658_1 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000002052 241.0
PYH1_k127_941658_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000001584 188.0
PYH1_k127_941658_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000477 171.0
PYH1_k127_941658_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000002375 174.0
PYH1_k127_941658_5 Acetyltransferase (Isoleucine patch superfamily) - - - 0.0000000000000000000000000000000000000003183 158.0
PYH1_k127_941658_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000001441 149.0
PYH1_k127_946289_0 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 455.0
PYH1_k127_946289_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 250.0
PYH1_k127_946289_2 Binding-protein-dependent transport system inner membrane component K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000009427 248.0
PYH1_k127_990591_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 6.068e-247 784.0
PYH1_k127_990591_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 595.0
PYH1_k127_990591_10 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000001693 165.0
PYH1_k127_990591_11 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000009521 150.0
PYH1_k127_990591_12 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000003157 136.0
PYH1_k127_990591_13 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000007728 126.0
PYH1_k127_990591_14 CYTH K05873 - 4.6.1.1 0.00000000000000000001773 98.0
PYH1_k127_990591_15 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000001703 99.0
PYH1_k127_990591_17 beta' subunit K01754 - 4.3.1.19 0.0000005834 52.0
PYH1_k127_990591_18 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0007587 49.0
PYH1_k127_990591_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 495.0
PYH1_k127_990591_3 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 440.0
PYH1_k127_990591_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 422.0
PYH1_k127_990591_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004289 274.0
PYH1_k127_990591_6 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000004122 243.0
PYH1_k127_990591_7 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000001206 253.0
PYH1_k127_990591_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000008424 220.0
PYH1_k127_990591_9 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000000000000000002519 202.0
PYH1_k127_993851_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 501.0
PYH1_k127_993851_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 436.0
PYH1_k127_993851_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 312.0
PYH1_k127_993851_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000005624 156.0