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Overview

ID MAG03147
Name PYH1_bin.4
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Sulfuricellaceae
Genus Sulfuricella
Species
Assembly information
Completeness (%) 79.72
Contamination (%) 3.15
GC content (%) 57.0
N50 (bp) 8,796
Genome size (bp) 2,318,862

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2413

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1022442_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2677.0
PYH1_k127_1022442_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 999.0
PYH1_k127_1022442_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 529.0
PYH1_k127_1022442_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009134 429.0
PYH1_k127_1022442_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 353.0
PYH1_k127_1022442_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 329.0
PYH1_k127_1022442_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 280.0
PYH1_k127_1022442_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000000000001225 213.0
PYH1_k127_1022442_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000000000000000000000005522 206.0
PYH1_k127_1022442_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000835 50.0
PYH1_k127_1032496_0 AsmA family K07289 - - 0.0 1084.0
PYH1_k127_1032496_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 499.0
PYH1_k127_1032496_2 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 432.0
PYH1_k127_1032496_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 427.0
PYH1_k127_1032496_4 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000000000000000000008063 128.0
PYH1_k127_1032496_5 PFAM PsiF repeat protein - - - 0.0000000000000000003745 87.0
PYH1_k127_1034317_0 Diguanylate cyclase - - - 0.0 1714.0
PYH1_k127_1034317_1 Threonine synthase K01733 - 4.2.3.1 1.023e-296 917.0
PYH1_k127_1034317_2 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 4.161e-267 823.0
PYH1_k127_1034317_3 homoserine dehydrogenase K00003 - 1.1.1.3 1.279e-263 814.0
PYH1_k127_1034317_4 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000000000000000000000000007073 226.0
PYH1_k127_1034317_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000001763 133.0
PYH1_k127_1034317_6 periplasmic secreted protein - - - 0.00000000000000000003315 96.0
PYH1_k127_1049796_0 Protein of unknown function - - - 0.0 2325.0
PYH1_k127_1049796_1 CoA-binding domain protein K09181 - - 0.0 1677.0
PYH1_k127_1049796_10 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005488 226.0
PYH1_k127_1049796_12 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000002464 173.0
PYH1_k127_1049796_13 Histidine kinase - - - 0.0000000000152 66.0
PYH1_k127_1049796_2 peptidase U62, modulator of DNA gyrase K03568 - - 2.181e-311 955.0
PYH1_k127_1049796_3 AAA domain K07028 - - 8.995e-270 836.0
PYH1_k127_1049796_4 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 604.0
PYH1_k127_1049796_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 561.0
PYH1_k127_1049796_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 505.0
PYH1_k127_1049796_7 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 440.0
PYH1_k127_1049796_8 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004119 259.0
PYH1_k127_1049796_9 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002677 241.0
PYH1_k127_1054187_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1187.0
PYH1_k127_1054187_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.94e-299 927.0
PYH1_k127_1054187_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.887e-294 906.0
PYH1_k127_1054187_3 Cell shape determining protein, MreB Mrl family K03569 - - 4.221e-216 672.0
PYH1_k127_1054187_4 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 515.0
PYH1_k127_1054187_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 486.0
PYH1_k127_1054187_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 451.0
PYH1_k127_1054187_7 COG2202 FOG PAS PAC domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 378.0
PYH1_k127_1054187_8 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 330.0
PYH1_k127_1054187_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000004173 173.0
PYH1_k127_1054681_0 FAD dependent oxidoreductase K09471 - - 2.572e-221 695.0
PYH1_k127_1054681_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 445.0
PYH1_k127_1064609_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 2.17e-297 912.0
PYH1_k127_1064609_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 604.0
PYH1_k127_1064609_2 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 417.0
PYH1_k127_1064609_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 351.0
PYH1_k127_1064609_4 - - - - 0.0000000000000000000000000000000000000000000000000000000008401 203.0
PYH1_k127_10857_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 412.0
PYH1_k127_10857_1 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
PYH1_k127_10857_2 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001163 274.0
PYH1_k127_10857_3 NTPase - - - 0.000000000000000000000000000000000000000000000000007439 185.0
PYH1_k127_10857_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000003373 128.0
PYH1_k127_1103797_0 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 610.0
PYH1_k127_1103797_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 407.0
PYH1_k127_1103797_2 HTH-type transcriptional regulator (heavy metal copper efflux protein) - - - 0.00000000000404 71.0
PYH1_k127_1106153_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.649e-221 688.0
PYH1_k127_1106153_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 550.0
PYH1_k127_1148673_0 Diguanylate cyclase - - - 0.0 1209.0
PYH1_k127_1148673_1 HDOD domain - - - 0.0 1205.0
PYH1_k127_1148673_2 transporter component K07112 - - 1.139e-237 747.0
PYH1_k127_1148673_3 Histidine Phosphotransfer domain - - - 2.291e-220 685.0
PYH1_k127_1148673_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 368.0
PYH1_k127_1148673_5 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000005795 235.0
PYH1_k127_1148673_6 Rhodanese Homology Domain - - - 0.000000000000000001643 85.0
PYH1_k127_1150675_0 Diguanylate cyclase - - - 0.0 1430.0
PYH1_k127_1158330_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 464.0
PYH1_k127_1158330_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 463.0
PYH1_k127_1158330_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 441.0
PYH1_k127_1158330_3 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 392.0
PYH1_k127_1158330_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 302.0
PYH1_k127_1235262_0 Cytochrome c bacterial - - - 2.071e-303 930.0
PYH1_k127_1235262_1 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 405.0
PYH1_k127_1235262_2 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000000000000003737 214.0
PYH1_k127_1258917_0 PFAM glycosyl transferase family 39 - - - 0.0 1025.0
PYH1_k127_1258917_1 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 471.0
PYH1_k127_1258917_2 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 307.0
PYH1_k127_1258917_3 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
PYH1_k127_1258917_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000003945 167.0
PYH1_k127_1267068_0 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 4.584e-194 630.0
PYH1_k127_1267068_1 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000001159 88.0
PYH1_k127_1276389_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1e-321 991.0
PYH1_k127_1276389_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 4.502e-286 889.0
PYH1_k127_1276389_2 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 558.0
PYH1_k127_1276389_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 340.0
PYH1_k127_1276389_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 304.0
PYH1_k127_1280274_0 D-Amino acid dehydrogenase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 1.175e-194 610.0
PYH1_k127_1280274_1 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 378.0
PYH1_k127_1280274_2 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 283.0
PYH1_k127_1280274_3 type 4 fimbrial biogenesis K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009752 279.0
PYH1_k127_1280274_4 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000000000000001053 184.0
PYH1_k127_1280274_5 Prokaryotic N-terminal methylation motif K02655 - - 0.0000000000000000000000000000000000000001005 154.0
PYH1_k127_1280274_6 Tfp pilus assembly protein - - - 0.0000000000000000000000000000000001121 138.0
PYH1_k127_1280274_7 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000018 137.0
PYH1_k127_1289773_0 fad dependent oxidoreductase K07137 - - 0.0 1043.0
PYH1_k127_1289773_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000001187 70.0
PYH1_k127_1346055_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 581.0
PYH1_k127_1346055_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 494.0
PYH1_k127_1346055_2 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004515 254.0
PYH1_k127_1346055_3 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000000006389 183.0
PYH1_k127_1346055_4 NusG domain II - - - 0.00000000000000000000000000000000000007259 142.0
PYH1_k127_1383070_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0 1001.0
PYH1_k127_1383070_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 9.842e-213 667.0
PYH1_k127_1383070_2 CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 524.0
PYH1_k127_1383070_3 Response regulators consisting of a CheY-like receiver domain and a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 424.0
PYH1_k127_1384841_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 4.868e-225 702.0
PYH1_k127_1384841_1 lipopolysaccharide heptosyltransferase I K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 291.0
PYH1_k127_1384841_2 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000114 186.0
PYH1_k127_1400811_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 438.0
PYH1_k127_1400811_1 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 350.0
PYH1_k127_1400811_2 - - - - 0.0000000002353 68.0
PYH1_k127_1402881_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 547.0
PYH1_k127_1402881_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 550.0
PYH1_k127_1402881_2 RNA polymerase sigma factor RpoS K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 507.0
PYH1_k127_1402881_3 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 462.0
PYH1_k127_1402881_4 Sigma factor PP2C-like phosphatases K20977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 474.0
PYH1_k127_1402881_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 419.0
PYH1_k127_1402881_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 325.0
PYH1_k127_1402881_7 CheD chemotactic sensory transduction K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 300.0
PYH1_k127_1402881_8 methyl-accepting chemotaxis protein K03406,K03776,K05874,K05875 - - 0.00000000000000000000000000000000000000000000001744 175.0
PYH1_k127_1402881_9 STAS domain K20978 - - 0.00000000000000000000000002844 110.0
PYH1_k127_1404311_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0 1464.0
PYH1_k127_1404311_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1345.0
PYH1_k127_1404311_10 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 370.0
PYH1_k127_1404311_11 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 346.0
PYH1_k127_1404311_12 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 336.0
PYH1_k127_1404311_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 292.0
PYH1_k127_1404311_15 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
PYH1_k127_1404311_16 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000000000002488 224.0
PYH1_k127_1404311_17 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000000000004088 131.0
PYH1_k127_1404311_19 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000001983 113.0
PYH1_k127_1404311_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1264.0
PYH1_k127_1404311_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 6.333e-247 764.0
PYH1_k127_1404311_4 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 604.0
PYH1_k127_1404311_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 595.0
PYH1_k127_1404311_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 520.0
PYH1_k127_1404311_7 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 450.0
PYH1_k127_1404311_8 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 416.0
PYH1_k127_1404311_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 411.0
PYH1_k127_143096_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0 1415.0
PYH1_k127_143096_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 4.227e-242 750.0
PYH1_k127_143096_2 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 384.0
PYH1_k127_143096_3 PFAM globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009241 243.0
PYH1_k127_143096_4 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000003266 173.0
PYH1_k127_1440827_0 Sodium:solute symporter family K14393 - - 0.0 1165.0
PYH1_k127_1440827_1 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 421.0
PYH1_k127_1440827_2 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000006345 177.0
PYH1_k127_1440827_3 - - - - 0.0000000000000000000000000000000000000000000005666 169.0
PYH1_k127_1440827_4 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000000000000301 159.0
PYH1_k127_1440827_5 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000008001 89.0
PYH1_k127_1443598_0 dinuclear metal center protein, YbgI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 446.0
PYH1_k127_1443598_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 368.0
PYH1_k127_1443598_2 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 335.0
PYH1_k127_1443598_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 325.0
PYH1_k127_1504860_0 GGDEF domain - - - 8.357e-207 679.0
PYH1_k127_1504860_1 Methyltransferase, YaeB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 450.0
PYH1_k127_1504860_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 416.0
PYH1_k127_1504860_3 Molydopterin dinucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 361.0
PYH1_k127_1504860_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 351.0
PYH1_k127_1504860_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 312.0
PYH1_k127_1504860_6 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000003824 100.0
PYH1_k127_1523952_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0 1360.0
PYH1_k127_1523952_1 Belongs to the HypD family K04654 - - 5.949e-234 724.0
PYH1_k127_1523952_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000006092 152.0
PYH1_k127_1523952_3 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000000000000002285 141.0
PYH1_k127_1523952_4 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000008221 127.0
PYH1_k127_1541418_0 Helicase K03722 - 3.6.4.12 0.0 1247.0
PYH1_k127_1541418_1 Peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 412.0
PYH1_k127_1541418_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 365.0
PYH1_k127_1541418_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 291.0
PYH1_k127_1541418_4 HIRAN - - - 0.000000000000000000000000000000000000000000000000000000000006416 209.0
PYH1_k127_1541418_5 hydrogenase maturation protease - - - 0.000000000000000000005991 92.0
PYH1_k127_1567319_0 RNA binding S1 domain protein K06959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 339.0
PYH1_k127_1567319_1 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 322.0
PYH1_k127_1567319_2 - - - - 0.000000000000000000000000000000004232 130.0
PYH1_k127_1582431_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.718e-233 729.0
PYH1_k127_1582431_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 337.0
PYH1_k127_1582431_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002019 276.0
PYH1_k127_1582431_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000657 144.0
PYH1_k127_1582431_4 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000003849 91.0
PYH1_k127_1582431_5 ATP synthase subunit C K02110 - - 0.000000000000001822 79.0
PYH1_k127_1582431_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000003178 79.0
PYH1_k127_1611224_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 1.428e-235 732.0
PYH1_k127_1611224_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 535.0
PYH1_k127_1611224_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 488.0
PYH1_k127_1611224_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 450.0
PYH1_k127_1611224_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 346.0
PYH1_k127_1611224_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000176 242.0
PYH1_k127_1684641_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0 1114.0
PYH1_k127_1684641_1 Part of a membrane complex involved in electron transport K03615 - - 3.45e-292 902.0
PYH1_k127_1684641_10 - - - - 0.00000000000000000000000000000000000000000000000000000000002936 207.0
PYH1_k127_1684641_11 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000009007 183.0
PYH1_k127_1684641_12 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000004241 131.0
PYH1_k127_1684641_2 FIST_C - - - 5.202e-221 687.0
PYH1_k127_1684641_3 Part of a membrane complex involved in electron transport K03614 - - 4.229e-195 612.0
PYH1_k127_1684641_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 572.0
PYH1_k127_1684641_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 418.0
PYH1_k127_1684641_6 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 421.0
PYH1_k127_1684641_7 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 386.0
PYH1_k127_1684641_8 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 355.0
PYH1_k127_1684641_9 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 343.0
PYH1_k127_1690043_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1684.0
PYH1_k127_1690043_1 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 9.106e-314 960.0
PYH1_k127_1690043_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000988 253.0
PYH1_k127_1690043_11 response regulator K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000006194 77.0
PYH1_k127_1690043_2 Acts as a magnesium transporter K06213 - - 1.29e-279 864.0
PYH1_k127_1690043_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 5.292e-227 706.0
PYH1_k127_1690043_4 Phosphate transporter K03306 - - 4.034e-202 632.0
PYH1_k127_1690043_5 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 2.061e-196 616.0
PYH1_k127_1690043_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 546.0
PYH1_k127_1690043_7 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 376.0
PYH1_k127_1690043_8 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 366.0
PYH1_k127_1690043_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 359.0
PYH1_k127_1694540_0 Putative diguanylate phosphodiesterase - - - 0.0 1551.0
PYH1_k127_1694540_1 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 572.0
PYH1_k127_1694540_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 574.0
PYH1_k127_1694540_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 351.0
PYH1_k127_1694540_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
PYH1_k127_1694600_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1665.0
PYH1_k127_1694600_1 oxidoreductase FAD NAD(P)-binding domain protein - - - 1.621e-300 925.0
PYH1_k127_1694600_10 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 323.0
PYH1_k127_1694600_12 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001089 236.0
PYH1_k127_1694600_13 - - - - 0.000000000000000000000000000000002269 130.0
PYH1_k127_1694600_2 Major facilitator Superfamily K06902 - - 6.366e-253 785.0
PYH1_k127_1694600_3 Diguanylate cyclase K02488 - 2.7.7.65 3.906e-225 699.0
PYH1_k127_1694600_4 Chemotaxis sensory transducer K03406 - - 4.363e-208 651.0
PYH1_k127_1694600_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 559.0
PYH1_k127_1694600_6 ketose-bisphosphate aldolase K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 523.0
PYH1_k127_1694600_7 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 470.0
PYH1_k127_1694600_8 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 379.0
PYH1_k127_1694600_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 323.0
PYH1_k127_1703652_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1411.0
PYH1_k127_1703652_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1292.0
PYH1_k127_1703652_10 malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 571.0
PYH1_k127_1703652_11 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 423.0
PYH1_k127_1703652_12 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
PYH1_k127_1703652_13 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 362.0
PYH1_k127_1703652_14 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 343.0
PYH1_k127_1703652_15 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 306.0
PYH1_k127_1703652_16 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001615 276.0
PYH1_k127_1703652_17 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000000003389 126.0
PYH1_k127_1703652_18 Modulator of Rho-dependent transcription termination (ROF) K19000 - - 0.00000000000000000000000000001787 123.0
PYH1_k127_1703652_2 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0 1132.0
PYH1_k127_1703652_20 Belongs to the 'phage' integrase family - - - 0.0001627 48.0
PYH1_k127_1703652_3 acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 1.079e-304 935.0
PYH1_k127_1703652_4 Aminotransferase K00812 - 2.6.1.1 7.452e-246 761.0
PYH1_k127_1703652_5 Protein involved in outer membrane biogenesis - - - 6.491e-236 735.0
PYH1_k127_1703652_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 3.338e-209 651.0
PYH1_k127_1703652_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 1.049e-201 629.0
PYH1_k127_1703652_8 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 7.674e-196 612.0
PYH1_k127_1703652_9 peptidase, S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 589.0
PYH1_k127_1704189_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 543.0
PYH1_k127_1704189_1 Mota tolq exbb proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 374.0
PYH1_k127_1704189_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000797 279.0
PYH1_k127_1704189_3 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007191 248.0
PYH1_k127_1704189_4 Trm112p-like protein K09791 - - 0.0000000000000007925 78.0
PYH1_k127_1770676_0 Major Facilitator - - - 2.607e-280 864.0
PYH1_k127_1770676_1 Major Facilitator Superfamily K02575 - - 8.556e-265 821.0
PYH1_k127_1770676_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000001587 230.0
PYH1_k127_1770676_11 Redoxin - - - 0.000000000000000000000000000000000000000000000000005427 186.0
PYH1_k127_1770676_12 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000009854 181.0
PYH1_k127_1770676_13 - - - - 0.00000000000000000000000000000000000000000000001253 178.0
PYH1_k127_1770676_14 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000001052 84.0
PYH1_k127_1770676_2 Major Facilitator Superfamily K02575 - - 4.506e-231 720.0
PYH1_k127_1770676_3 Flagellar assembly protein T, middle domain - - - 1.371e-227 714.0
PYH1_k127_1770676_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07673 - 2.7.13.3 3.125e-196 632.0
PYH1_k127_1770676_5 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 484.0
PYH1_k127_1770676_6 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 421.0
PYH1_k127_1770676_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 404.0
PYH1_k127_1770676_8 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 382.0
PYH1_k127_1770676_9 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 294.0
PYH1_k127_1825686_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1389.0
PYH1_k127_1825686_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 306.0
PYH1_k127_1825686_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008381 250.0
PYH1_k127_1825686_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000003034 87.0
PYH1_k127_183185_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 6.75e-262 807.0
PYH1_k127_183185_1 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 301.0
PYH1_k127_183185_2 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008253 273.0
PYH1_k127_183185_3 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH1_k127_183185_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000001137 227.0
PYH1_k127_1833994_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1154.0
PYH1_k127_1833994_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 375.0
PYH1_k127_1833994_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 348.0
PYH1_k127_1833994_3 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 286.0
PYH1_k127_1835471_0 Protein of unknown function (DUF3485) - - - 2.98e-273 845.0
PYH1_k127_1835471_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 421.0
PYH1_k127_1835471_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 407.0
PYH1_k127_1871519_0 HflC and HflK could encode or regulate a protease K04088 - - 6.87e-230 715.0
PYH1_k127_1871519_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 578.0
PYH1_k127_1871519_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 488.0
PYH1_k127_1907847_0 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 1.549e-243 753.0
PYH1_k127_1907847_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 596.0
PYH1_k127_1907847_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 410.0
PYH1_k127_1907847_3 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 389.0
PYH1_k127_1916502_0 PFAM Transposase DDE domain K07495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 455.0
PYH1_k127_1916502_1 phospholipase C K01114 - 3.1.4.3 0.0000002968 53.0
PYH1_k127_1916502_2 Transcriptional regulator K06921 - - 0.0003485 46.0
PYH1_k127_1916653_0 EAL domain - - - 0.0 1073.0
PYH1_k127_1916653_1 Response regulator receiver - - - 5.679e-292 903.0
PYH1_k127_1916653_10 Psort location CytoplasmicMembrane, score - - - 0.00001554 55.0
PYH1_k127_1916653_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 566.0
PYH1_k127_1916653_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 545.0
PYH1_k127_1916653_4 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 470.0
PYH1_k127_1916653_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 293.0
PYH1_k127_1916653_6 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
PYH1_k127_1916653_7 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000001197 144.0
PYH1_k127_1916653_8 - - - - 0.0000000000000000000000000000000000003458 141.0
PYH1_k127_1916653_9 - - - - 0.00000000000000000000000000000000242 130.0
PYH1_k127_1923951_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0 1097.0
PYH1_k127_1923951_1 response regulator K10943 - - 6.95e-264 816.0
PYH1_k127_1923951_10 VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 444.0
PYH1_k127_1923951_11 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 423.0
PYH1_k127_1923951_12 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 318.0
PYH1_k127_1923951_13 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002652 248.0
PYH1_k127_1923951_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009693 243.0
PYH1_k127_1923951_15 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000002548 215.0
PYH1_k127_1923951_16 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000001031 180.0
PYH1_k127_1923951_17 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000000000000000004796 138.0
PYH1_k127_1923951_2 PFAM EAL domain protein - - - 2.484e-239 745.0
PYH1_k127_1923951_3 signal transduction histidine kinase K10942 - 2.7.13.3 1.349e-217 680.0
PYH1_k127_1923951_4 DMSO reductase anchor subunit (DmsC) K21309 - - 7.137e-194 608.0
PYH1_k127_1923951_5 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 592.0
PYH1_k127_1923951_6 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 583.0
PYH1_k127_1923951_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 553.0
PYH1_k127_1923951_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 516.0
PYH1_k127_1923951_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 510.0
PYH1_k127_1992304_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1132.0
PYH1_k127_1992304_1 Carbohydrate kinase - - - 6.262e-232 724.0
PYH1_k127_1992304_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 289.0
PYH1_k127_2000595_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1095.0
PYH1_k127_2000595_1 Participates in both transcription termination and antitermination K02600 - - 1.137e-295 911.0
PYH1_k127_2000595_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 574.0
PYH1_k127_2000595_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001813 275.0
PYH1_k127_2000595_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000000000000000000002142 236.0
PYH1_k127_2000595_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000008191 104.0
PYH1_k127_20059_0 Helix-turn-helix type 11 - - - 1.412e-203 635.0
PYH1_k127_20059_1 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 427.0
PYH1_k127_20059_11 hydrolases of HD superfamily K06952 - - 0.00000000003128 64.0
PYH1_k127_20059_2 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 360.0
PYH1_k127_20059_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 339.0
PYH1_k127_20059_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 320.0
PYH1_k127_20059_5 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 257.0
PYH1_k127_20059_7 - - - - 0.00000000000000000000000000000000000000008173 151.0
PYH1_k127_2081629_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0 1262.0
PYH1_k127_2081629_1 oxidoreductase FAD NAD(P)-binding domain protein K00523 - 1.17.1.1 2.063e-211 660.0
PYH1_k127_2081629_10 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007118 231.0
PYH1_k127_2081629_11 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000003395 214.0
PYH1_k127_2081629_13 HemY domain protein K02498 - - 0.0000000000004449 68.0
PYH1_k127_2081629_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 579.0
PYH1_k127_2081629_4 acetyl-CoA carboxylase biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 396.0
PYH1_k127_2081629_5 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
PYH1_k127_2081629_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 308.0
PYH1_k127_2081629_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003558 276.0
PYH1_k127_2081629_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008978 264.0
PYH1_k127_2081629_9 FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000000000000000000000000000000005715 235.0
PYH1_k127_2165890_0 (ABC) transporter K05685,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 343.0
PYH1_k127_2165890_1 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002896 265.0
PYH1_k127_2165890_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
PYH1_k127_2167887_0 Belongs to the peptidase S16 family - - - 0.0 1201.0
PYH1_k127_2167887_1 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 4.415e-220 686.0
PYH1_k127_2167887_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 341.0
PYH1_k127_2167887_11 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 327.0
PYH1_k127_2167887_12 Histidine kinase K07675,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 338.0
PYH1_k127_2167887_13 PFAM transport-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 321.0
PYH1_k127_2167887_14 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 297.0
PYH1_k127_2167887_15 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 297.0
PYH1_k127_2167887_16 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
PYH1_k127_2167887_17 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 271.0
PYH1_k127_2167887_18 Bacterial regulatory protein, arsR family K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002884 242.0
PYH1_k127_2167887_19 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000005739 197.0
PYH1_k127_2167887_2 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 576.0
PYH1_k127_2167887_20 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000001642 204.0
PYH1_k127_2167887_21 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000001676 177.0
PYH1_k127_2167887_22 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000006012 166.0
PYH1_k127_2167887_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000128 156.0
PYH1_k127_2167887_24 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000000003109 152.0
PYH1_k127_2167887_26 tigrfam pas - - - 0.00000000000000000000000000000000002588 145.0
PYH1_k127_2167887_27 - - - - 0.000000000000000000000000000000003118 129.0
PYH1_k127_2167887_28 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000005425 129.0
PYH1_k127_2167887_29 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.00000000000000000000000000000001036 126.0
PYH1_k127_2167887_3 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 568.0
PYH1_k127_2167887_30 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000005378 124.0
PYH1_k127_2167887_4 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 569.0
PYH1_k127_2167887_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 531.0
PYH1_k127_2167887_6 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 522.0
PYH1_k127_2167887_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 390.0
PYH1_k127_2167887_8 Cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 365.0
PYH1_k127_2167887_9 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 354.0
PYH1_k127_2171756_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 3.554e-278 856.0
PYH1_k127_2171756_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 489.0
PYH1_k127_2171756_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000000000003632 187.0
PYH1_k127_2171756_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000002449 105.0
PYH1_k127_2187238_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 607.0
PYH1_k127_2187238_1 SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 308.0
PYH1_k127_22002_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1354.0
PYH1_k127_22002_1 Inositol-1-monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 502.0
PYH1_k127_22002_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 379.0
PYH1_k127_22002_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000872 178.0
PYH1_k127_225579_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 552.0
PYH1_k127_225579_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 402.0
PYH1_k127_225579_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 401.0
PYH1_k127_225579_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000000281 202.0
PYH1_k127_225579_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000000000000008816 201.0
PYH1_k127_225579_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000004611 186.0
PYH1_k127_2280462_0 ABC transporter transmembrane region K06148 - - 0.0 1090.0
PYH1_k127_2280462_1 PFAM CHASE2 domain - - - 0.0 1015.0
PYH1_k127_2280462_11 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000002949 158.0
PYH1_k127_2280462_12 - - - - 0.00000000000000000000000000000000004306 143.0
PYH1_k127_2280462_2 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 4.049e-223 694.0
PYH1_k127_2280462_3 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 517.0
PYH1_k127_2280462_4 Pfam Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 408.0
PYH1_k127_2280462_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 361.0
PYH1_k127_2280462_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 345.0
PYH1_k127_2280462_7 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 293.0
PYH1_k127_2280462_8 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 286.0
PYH1_k127_2280462_9 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000000000000000000004637 233.0
PYH1_k127_228112_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0 1057.0
PYH1_k127_228112_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 5.491e-306 940.0
PYH1_k127_228112_2 NADH ubiquinone oxidoreductase K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 432.0
PYH1_k127_228112_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 331.0
PYH1_k127_228112_4 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 287.0
PYH1_k127_228112_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000001601 91.0
PYH1_k127_228112_6 Helicase K03722 - 3.6.4.12 0.0000000005304 61.0
PYH1_k127_2311478_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 0.0 1242.0
PYH1_k127_2311478_1 RESPONSE REGULATOR receiver - - - 0.0 1151.0
PYH1_k127_2311478_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 531.0
PYH1_k127_2311478_11 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 494.0
PYH1_k127_2311478_12 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 401.0
PYH1_k127_2311478_13 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 390.0
PYH1_k127_2311478_14 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
PYH1_k127_2311478_15 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 297.0
PYH1_k127_2311478_16 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000000000006061 205.0
PYH1_k127_2311478_18 aminopeptidase activity - - - 0.0000003583 51.0
PYH1_k127_2311478_2 DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity K02343 - 2.7.7.7 1.934e-298 925.0
PYH1_k127_2311478_3 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 1.891e-279 862.0
PYH1_k127_2311478_4 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.1e-276 856.0
PYH1_k127_2311478_5 Dehydrogenase E1 component K00164 - 1.2.4.2 9.966e-262 808.0
PYH1_k127_2311478_6 PFAM AFG1-family ATPase K06916 - - 2.776e-209 654.0
PYH1_k127_2311478_7 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 1.904e-196 617.0
PYH1_k127_2311478_8 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 5.905e-194 608.0
PYH1_k127_2311478_9 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 605.0
PYH1_k127_2349831_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0 1375.0
PYH1_k127_2349831_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 5.311e-238 736.0
PYH1_k127_2349831_2 Major facilitator Superfamily K05820 - - 4.278e-232 721.0
PYH1_k127_2349831_3 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 563.0
PYH1_k127_2349831_4 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 505.0
PYH1_k127_2349831_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008445 261.0
PYH1_k127_2349831_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000000001194 184.0
PYH1_k127_2349831_7 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000000000000000002501 173.0
PYH1_k127_2349831_8 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000001609 166.0
PYH1_k127_2349831_9 Protein of unknown function (DUF3018) - - - 0.00000000000000000000000000000000001151 136.0
PYH1_k127_241936_0 Protein of unknown function (DUF1015) - - - 2.684e-246 763.0
PYH1_k127_241936_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000008425 194.0
PYH1_k127_2441884_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1345.0
PYH1_k127_2441884_1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 518.0
PYH1_k127_2441884_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 384.0
PYH1_k127_2441884_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000001093 135.0
PYH1_k127_25008_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1763.0
PYH1_k127_25008_1 type II secretion system protein E K02454,K02504,K02652,K12276 - - 0.0 1094.0
PYH1_k127_25008_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 562.0
PYH1_k127_25008_11 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
PYH1_k127_25008_12 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 482.0
PYH1_k127_25008_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 470.0
PYH1_k127_25008_14 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 402.0
PYH1_k127_25008_15 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 318.0
PYH1_k127_25008_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000456 246.0
PYH1_k127_25008_17 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000000000000000000000000000000000000000729 228.0
PYH1_k127_25008_18 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000004671 82.0
PYH1_k127_25008_19 - - - - 0.00004516 48.0
PYH1_k127_25008_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.82e-260 802.0
PYH1_k127_25008_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 3.839e-238 741.0
PYH1_k127_25008_4 CBS domain containing protein - - - 8.325e-235 730.0
PYH1_k127_25008_5 Type II secretion system K02653 - - 5.698e-233 724.0
PYH1_k127_25008_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 4.568e-231 717.0
PYH1_k127_25008_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 588.0
PYH1_k127_25008_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 565.0
PYH1_k127_25008_9 peptidase K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 563.0
PYH1_k127_2517659_0 Metal-dependent hydrolase HDOD - - - 0.0 1462.0
PYH1_k127_2517659_1 Metal-dependent hydrolase HDOD - - - 0.0 1356.0
PYH1_k127_2517659_2 von Willebrand factor, type A K02448 - - 0.0 1164.0
PYH1_k127_2517659_3 PFAM NnrS family protein K07234 - - 2.809e-253 782.0
PYH1_k127_2517659_4 Radical_SAM C-terminal domain K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 604.0
PYH1_k127_2517659_5 COG2202 FOG PAS PAC domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 541.0
PYH1_k127_2517659_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 494.0
PYH1_k127_2517659_7 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005485 247.0
PYH1_k127_2517659_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005468 243.0
PYH1_k127_2517659_9 SlyX K03745 - - 0.00000000000000000000000000001942 119.0
PYH1_k127_2519927_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 1.159e-273 846.0
PYH1_k127_2519927_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 449.0
PYH1_k127_2519927_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000004207 238.0
PYH1_k127_2531154_0 serine threonine protein kinase - - - 8.071e-197 615.0
PYH1_k127_2531154_1 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 584.0
PYH1_k127_2531154_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 317.0
PYH1_k127_2537823_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1887.0
PYH1_k127_2537823_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1639.0
PYH1_k127_2537823_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 591.0
PYH1_k127_2537823_3 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 593.0
PYH1_k127_2537823_4 PFAM HI0933 family protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 551.0
PYH1_k127_2537823_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 291.0
PYH1_k127_2537823_6 - - - - 0.000000000000000000000000000000000000000000000000000009485 190.0
PYH1_k127_2606706_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 0.0 1095.0
PYH1_k127_2606706_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 3.268e-247 766.0
PYH1_k127_2606706_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 502.0
PYH1_k127_2606706_3 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 392.0
PYH1_k127_2606706_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 346.0
PYH1_k127_2606706_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
PYH1_k127_2606706_6 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000002054 192.0
PYH1_k127_2606706_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000000000002349 140.0
PYH1_k127_2611366_0 MacB-like periplasmic core domain K02004 - - 6.808e-212 664.0
PYH1_k127_2611366_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 547.0
PYH1_k127_2611366_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 394.0
PYH1_k127_2611366_3 PIN domain - - - 0.0000006066 51.0
PYH1_k127_2612657_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.0 1118.0
PYH1_k127_2612657_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1067.0
PYH1_k127_2612657_10 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 298.0
PYH1_k127_2612657_11 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 290.0
PYH1_k127_2612657_12 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 291.0
PYH1_k127_2612657_13 Cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
PYH1_k127_2612657_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 284.0
PYH1_k127_2612657_16 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000006105 179.0
PYH1_k127_2612657_17 Protein of unknown function (DUF2288) - - - 0.000000000000000000000000000000000000000000002274 168.0
PYH1_k127_2612657_18 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000000001023 155.0
PYH1_k127_2612657_19 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000008638 153.0
PYH1_k127_2612657_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.408e-297 913.0
PYH1_k127_2612657_20 - K06078 - - 0.0000000000000000000000000000000000000001642 152.0
PYH1_k127_2612657_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 6.642e-199 621.0
PYH1_k127_2612657_4 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 578.0
PYH1_k127_2612657_5 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 569.0
PYH1_k127_2612657_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 553.0
PYH1_k127_2612657_7 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 531.0
PYH1_k127_2612657_8 Opioid growth factor receptor (OGFr) conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 311.0
PYH1_k127_2612657_9 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 302.0
PYH1_k127_2616048_0 GAF domain K20962 - 3.1.4.52 0.0 1405.0
PYH1_k127_2616048_1 Belongs to the peptidase S16 family - - - 1.293e-202 632.0
PYH1_k127_2616048_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
PYH1_k127_2641227_0 Heat shock 70 kDa protein K04043 - - 1.5e-297 923.0
PYH1_k127_2641227_1 Abc transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 505.0
PYH1_k127_2641227_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 510.0
PYH1_k127_2641227_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
PYH1_k127_2641227_4 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 300.0
PYH1_k127_2641227_5 Translation initiation factor K03113 - - 0.00000000000000000000000000000000000000000000000000000000000000001435 227.0
PYH1_k127_2641227_6 Peptidoglycan-binding domain 1 protein K03194,K07273,K08307,K08309,K12089 - - 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
PYH1_k127_2641227_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000000000000000000000001524 185.0
PYH1_k127_2661062_0 Phosphate-selective porin O and P - - - 1.073e-217 683.0
PYH1_k127_2661062_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 545.0
PYH1_k127_2661062_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 345.0
PYH1_k127_2661062_3 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 299.0
PYH1_k127_2661062_4 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000000000000002004 195.0
PYH1_k127_2723803_0 protein conserved in bacteria K07793 - - 1.019e-245 766.0
PYH1_k127_2723803_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 458.0
PYH1_k127_2723803_2 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000000000009328 203.0
PYH1_k127_2723803_3 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000174 189.0
PYH1_k127_2740100_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1344.0
PYH1_k127_2740100_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 565.0
PYH1_k127_2773701_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 2.175e-207 644.0
PYH1_k127_2773701_1 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 386.0
PYH1_k127_2773701_2 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 311.0
PYH1_k127_2773701_3 Histidine kinase K07679 - 2.7.13.3 0.00000000000000000000000001597 113.0
PYH1_k127_2776700_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1522.0
PYH1_k127_2776700_1 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 4.07e-272 845.0
PYH1_k127_2776700_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000000000000005382 205.0
PYH1_k127_2776700_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000000003242 167.0
PYH1_k127_2776700_12 PQ loop repeat K15383 - - 0.000000000000000000000000000000000000000006647 156.0
PYH1_k127_2776700_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000004347 118.0
PYH1_k127_2776700_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.42e-225 700.0
PYH1_k127_2776700_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 9.423e-218 681.0
PYH1_k127_2776700_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 606.0
PYH1_k127_2776700_5 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 597.0
PYH1_k127_2776700_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 494.0
PYH1_k127_2776700_7 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 416.0
PYH1_k127_2776700_8 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 397.0
PYH1_k127_2776700_9 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 374.0
PYH1_k127_2801407_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
PYH1_k127_2801407_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 291.0
PYH1_k127_2801407_2 CYTH domain - - - 0.000000000000000000000000000000000000000000000000000000004996 204.0
PYH1_k127_2801407_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000007227 190.0
PYH1_k127_2802007_0 Putative diguanylate phosphodiesterase - - - 0.0 1613.0
PYH1_k127_2802007_1 von Willebrand factor, type A - - - 0.0 1472.0
PYH1_k127_2802007_10 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 338.0
PYH1_k127_2802007_11 NADH ubiquinone plastoquinone (Complex I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 291.0
PYH1_k127_2802007_12 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000001758 239.0
PYH1_k127_2802007_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0 1009.0
PYH1_k127_2802007_3 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 6.732e-320 979.0
PYH1_k127_2802007_4 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 2.23e-303 932.0
PYH1_k127_2802007_5 Transcriptional regulator K21703 - - 2.727e-201 628.0
PYH1_k127_2802007_6 Carboxysome Shell Carbonic Anhydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 578.0
PYH1_k127_2802007_7 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 544.0
PYH1_k127_2802007_8 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 542.0
PYH1_k127_2802007_9 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 374.0
PYH1_k127_2837292_0 glycosyl hydrolase of K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 589.0
PYH1_k127_2837292_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 415.0
PYH1_k127_2837292_2 TPR repeat - - - 0.0003529 53.0
PYH1_k127_28596_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0 1029.0
PYH1_k127_28596_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 1.04e-321 989.0
PYH1_k127_28596_10 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 335.0
PYH1_k127_28596_11 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009264 264.0
PYH1_k127_28596_12 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000000000000000005375 253.0
PYH1_k127_28596_13 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000005666 186.0
PYH1_k127_28596_14 phosphocarrier protein Hpr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000007812 164.0
PYH1_k127_28596_2 ATP synthase F1, epsilon subunit - - - 2.405e-266 829.0
PYH1_k127_28596_3 glutamate--cysteine ligase K01919 - 6.3.2.2 1.623e-259 802.0
PYH1_k127_28596_4 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 4.59e-246 760.0
PYH1_k127_28596_5 twitching motility protein K02670 - - 1.261e-233 725.0
PYH1_k127_28596_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 4.041e-195 612.0
PYH1_k127_28596_7 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 565.0
PYH1_k127_28596_8 COG2202 FOG PAS PAC domain K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 529.0
PYH1_k127_28596_9 twitching motility protein K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 349.0
PYH1_k127_2864832_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.392e-314 965.0
PYH1_k127_2864832_1 histidine kinase A domain protein K07679 - 2.7.13.3 1.304e-196 658.0
PYH1_k127_2864832_2 Histidine kinase K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 528.0
PYH1_k127_2864832_3 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 318.0
PYH1_k127_2864832_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000004866 170.0
PYH1_k127_2864832_5 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0002416 44.0
PYH1_k127_289348_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1121.0
PYH1_k127_289348_1 The M ring may be actively involved in energy transduction K02409 - - 2.581e-315 969.0
PYH1_k127_289348_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 340.0
PYH1_k127_289348_11 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 311.0
PYH1_k127_289348_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 306.0
PYH1_k127_289348_13 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 284.0
PYH1_k127_289348_14 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 285.0
PYH1_k127_289348_15 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 284.0
PYH1_k127_289348_16 Flagellar export protein FliJ K02413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002792 266.0
PYH1_k127_289348_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000001262 245.0
PYH1_k127_289348_18 PFAM flagellar biosynthesis protein, FliO K02418 - - 0.00000000000000000000000000000000000000000000000000000000000000001781 226.0
PYH1_k127_289348_19 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000002793 224.0
PYH1_k127_289348_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 6.114e-252 790.0
PYH1_k127_289348_20 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000005558 211.0
PYH1_k127_289348_21 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.000000000000000000000000000000000000000000000000000319 191.0
PYH1_k127_289348_22 flagellar motor switch protein K02417 - - 0.000000000000000000000000000000000000000000000000719 180.0
PYH1_k127_289348_23 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000000000000000000001446 153.0
PYH1_k127_289348_25 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000004008 125.0
PYH1_k127_289348_3 (Lipo)protein K07287 - - 7.141e-220 685.0
PYH1_k127_289348_4 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 1.457e-209 660.0
PYH1_k127_289348_5 Flagellar motor switch protein K02416 - - 2.043e-205 640.0
PYH1_k127_289348_6 Flagellar hook-length control protein K02414 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 495.0
PYH1_k127_289348_7 flagellar motor switch protein K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 474.0
PYH1_k127_289348_8 Flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 464.0
PYH1_k127_289348_9 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 421.0
PYH1_k127_2902604_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1236.0
PYH1_k127_2902604_1 protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 342.0
PYH1_k127_2902604_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 323.0
PYH1_k127_2902604_3 protein conserved in bacteria K09796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
PYH1_k127_2902604_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001278 273.0
PYH1_k127_2902604_5 PFAM Carbohydrate-selective porin OprB K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007448 279.0
PYH1_k127_2902604_6 Protein of unknown function (DUF3135) - - - 0.0000000000000000000005813 99.0
PYH1_k127_291468_0 argininosuccinate lyase K01755 - 4.3.2.1 2.207e-292 903.0
PYH1_k127_291468_1 HemY domain protein K02498 - - 3.078e-220 687.0
PYH1_k127_291468_10 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002774 231.0
PYH1_k127_291468_11 Ribonucleotide reductase subunit alpha - - - 0.000000000000000000000000000000000000007573 149.0
PYH1_k127_291468_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.728e-211 658.0
PYH1_k127_291468_3 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 3.94e-199 623.0
PYH1_k127_291468_4 Histidine kinase K08082 - 2.7.13.3 2.369e-195 614.0
PYH1_k127_291468_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 583.0
PYH1_k127_291468_6 synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 452.0
PYH1_k127_291468_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 443.0
PYH1_k127_291468_8 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 310.0
PYH1_k127_291468_9 Peptidase S24-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004482 241.0
PYH1_k127_2934869_0 Ferrous iron transport protein B K04759 - - 0.0 1118.0
PYH1_k127_2934869_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1095.0
PYH1_k127_2934869_10 PFAM FeoA family protein K04758 - - 0.00000000000002612 86.0
PYH1_k127_2934869_2 Metal-dependent hydrolase HDOD - - - 1.084e-280 867.0
PYH1_k127_2934869_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 7.113e-254 785.0
PYH1_k127_2934869_4 PFAM type II secretion system protein E K02670 - - 9.506e-219 684.0
PYH1_k127_2934869_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 627.0
PYH1_k127_2934869_6 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 548.0
PYH1_k127_2934869_7 methyltransferase K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 412.0
PYH1_k127_2934869_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 350.0
PYH1_k127_2934869_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000000000000000000000000000008722 205.0
PYH1_k127_2938928_0 - K07341 - - 0.0000000000000000000000000000000000000000002468 162.0
PYH1_k127_2938928_2 acid phosphatase activity - - - 0.000000002609 59.0
PYH1_k127_2938928_3 Sulfatase-modifying factor enzyme 1 - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135 - 0.00000002735 61.0
PYH1_k127_2938928_4 Domain of unknown function (DUF4143) - - - 0.00003168 53.0
PYH1_k127_2953152_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1887.0
PYH1_k127_2953152_1 Major facilitator Superfamily - - - 3.935e-273 846.0
PYH1_k127_2953152_10 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001458 269.0
PYH1_k127_2953152_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008029 254.0
PYH1_k127_2953152_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009314 252.0
PYH1_k127_2953152_13 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004237 246.0
PYH1_k127_2953152_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001402 244.0
PYH1_k127_2953152_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
PYH1_k127_2953152_16 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000003081 231.0
PYH1_k127_2953152_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000001713 225.0
PYH1_k127_2953152_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000009142 216.0
PYH1_k127_2953152_19 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
PYH1_k127_2953152_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.004e-265 821.0
PYH1_k127_2953152_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000000000001068 182.0
PYH1_k127_2953152_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000002738 167.0
PYH1_k127_2953152_22 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000002031 147.0
PYH1_k127_2953152_23 Ribosomal protein L30 K02907 - - 0.000000000000000000000000000002266 120.0
PYH1_k127_2953152_24 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000005297 115.0
PYH1_k127_2953152_25 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001275 68.0
PYH1_k127_2953152_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 8.4e-206 642.0
PYH1_k127_2953152_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 459.0
PYH1_k127_2953152_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 416.0
PYH1_k127_2953152_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 361.0
PYH1_k127_2953152_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 337.0
PYH1_k127_2953152_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 331.0
PYH1_k127_2953152_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 294.0
PYH1_k127_2967700_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002456 255.0
PYH1_k127_2967700_1 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000002133 190.0
PYH1_k127_300031_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004208 239.0
PYH1_k127_300031_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000005985 213.0
PYH1_k127_3030826_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 490.0
PYH1_k127_3030826_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 460.0
PYH1_k127_3030826_2 Thioredoxin-like K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 319.0
PYH1_k127_3030826_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 289.0
PYH1_k127_3032859_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.167e-274 846.0
PYH1_k127_3032859_1 Zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 490.0
PYH1_k127_3032859_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 368.0
PYH1_k127_3032859_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001812 261.0
PYH1_k127_3032859_5 - - - - 0.0000000000000000000000000000000000000000000000007239 175.0
PYH1_k127_3032859_6 Heavy metal-associated domain protein K07213 - - 0.000000000000000000000000000833 113.0
PYH1_k127_3076475_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1183.0
PYH1_k127_3076475_1 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001435 242.0
PYH1_k127_3076475_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000001229 175.0
PYH1_k127_3076475_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000005164 163.0
PYH1_k127_3081868_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 3.888e-220 684.0
PYH1_k127_3081868_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 5.846e-198 617.0
PYH1_k127_3081868_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 462.0
PYH1_k127_3081868_3 COG2202 FOG PAS PAC domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 471.0
PYH1_k127_3081868_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 402.0
PYH1_k127_3081868_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 377.0
PYH1_k127_3081868_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 341.0
PYH1_k127_3081868_7 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003724 221.0
PYH1_k127_3081868_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000001037 183.0
PYH1_k127_3095953_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1842.0
PYH1_k127_3095953_1 Belongs to the CarA family K01956 - 6.3.5.5 1.403e-232 721.0
PYH1_k127_3095953_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 377.0
PYH1_k127_3104691_0 FAD linked oxidase domain protein - - - 1.513e-240 745.0
PYH1_k127_3104691_1 SMART Elongator protein 3 MiaB NifB - - - 7.562e-196 622.0
PYH1_k127_3104691_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001102 240.0
PYH1_k127_313874_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 3.348e-234 728.0
PYH1_k127_313874_1 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 407.0
PYH1_k127_3220483_0 PFAM UMUC domain protein DNA-repair protein K03502 - - 1.238e-245 761.0
PYH1_k127_3220483_1 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 572.0
PYH1_k127_3220483_2 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 564.0
PYH1_k127_3220483_3 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 380.0
PYH1_k127_3220483_4 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000009752 214.0
PYH1_k127_3237938_0 Transposase DDE domain group 1 - - - 4.217e-215 676.0
PYH1_k127_324511_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1613.0
PYH1_k127_324511_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1448.0
PYH1_k127_324511_10 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000589 217.0
PYH1_k127_324511_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000000001647 203.0
PYH1_k127_324511_12 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000000000005315 149.0
PYH1_k127_324511_13 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000000000001043 131.0
PYH1_k127_324511_14 - - - - 0.00000000000000000000000000000001251 128.0
PYH1_k127_324511_15 Domain of unknown function (DUF4124) - - - 0.000000000000003721 83.0
PYH1_k127_324511_2 peptidase m48, ste24p - - - 2.317e-276 853.0
PYH1_k127_324511_3 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 7.643e-276 848.0
PYH1_k127_324511_4 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 6.668e-274 846.0
PYH1_k127_324511_5 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 2.736e-267 825.0
PYH1_k127_324511_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 550.0
PYH1_k127_324511_7 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 396.0
PYH1_k127_324511_8 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 342.0
PYH1_k127_324511_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 287.0
PYH1_k127_3251202_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1456.0
PYH1_k127_3251202_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.533e-284 874.0
PYH1_k127_3251202_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.517e-230 714.0
PYH1_k127_3251202_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 7.327e-196 615.0
PYH1_k127_3251202_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 595.0
PYH1_k127_3251202_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 451.0
PYH1_k127_3251202_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004914 244.0
PYH1_k127_3251202_7 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
PYH1_k127_3251202_8 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000000000000000000000000000000000000000000001354 203.0
PYH1_k127_3251202_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000000000003106 181.0
PYH1_k127_3254565_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1183.0
PYH1_k127_3254565_1 NADH ubiquinone plastoquinone (Complex I) - - - 7.498e-279 864.0
PYH1_k127_3254565_2 overlaps another CDS with the same product name K00342 - 1.6.5.3 4.291e-199 631.0
PYH1_k127_3254565_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 613.0
PYH1_k127_3254565_4 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 557.0
PYH1_k127_3254565_5 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 554.0
PYH1_k127_3254565_6 Peptidase family S51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 388.0
PYH1_k127_3254565_7 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 370.0
PYH1_k127_3254565_8 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000005284 124.0
PYH1_k127_325693_0 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000004114 233.0
PYH1_k127_325693_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000000000000000000006963 198.0
PYH1_k127_325693_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 0.0000000000000000000000000000000000000000000000000000001892 198.0
PYH1_k127_3277606_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 449.0
PYH1_k127_3277606_1 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 443.0
PYH1_k127_3277606_2 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 297.0
PYH1_k127_3277606_3 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003394 256.0
PYH1_k127_3277606_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000003179 239.0
PYH1_k127_3282495_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 6.093e-212 661.0
PYH1_k127_3282495_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 431.0
PYH1_k127_3282495_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 408.0
PYH1_k127_3282495_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008942 246.0
PYH1_k127_3282495_4 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003716 238.0
PYH1_k127_3287111_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 4.587e-270 833.0
PYH1_k127_3287111_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 475.0
PYH1_k127_3287111_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 410.0
PYH1_k127_3287111_4 - - - - 0.00000000000000000000000001016 109.0
PYH1_k127_3288203_0 DinB superfamily - - - 0.0 1325.0
PYH1_k127_3288203_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 1.091e-261 812.0
PYH1_k127_3288203_2 Histidine kinase K07673 - 2.7.13.3 1.599e-244 757.0
PYH1_k127_3288203_3 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 521.0
PYH1_k127_3288203_4 response regulator K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 419.0
PYH1_k127_3288203_5 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006023 248.0
PYH1_k127_333751_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1482.0
PYH1_k127_333751_1 zinc metalloprotease K11749 - - 3.675e-268 829.0
PYH1_k127_333751_2 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 290.0
PYH1_k127_333751_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000003724 183.0
PYH1_k127_3366868_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1180.0
PYH1_k127_3366868_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - 0.0 1102.0
PYH1_k127_3366868_10 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 443.0
PYH1_k127_3366868_11 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 407.0
PYH1_k127_3366868_12 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 382.0
PYH1_k127_3366868_13 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 359.0
PYH1_k127_3366868_14 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005591 280.0
PYH1_k127_3366868_15 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 290.0
PYH1_k127_3366868_16 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005441 272.0
PYH1_k127_3366868_17 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001991 229.0
PYH1_k127_3366868_18 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000000000000000000000000006415 199.0
PYH1_k127_3366868_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000001971 135.0
PYH1_k127_3366868_2 photosynthesis K00575,K02453,K02656,K20543 - 2.1.1.80 0.0 1034.0
PYH1_k127_3366868_20 PFAM FecR protein - - - 0.000000000000000000000000000001278 139.0
PYH1_k127_3366868_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 2.199e-287 900.0
PYH1_k127_3366868_4 Polyphosphate kinase 2 (PPK2) - - - 9.337e-275 849.0
PYH1_k127_3366868_5 HD domain - - - 1.883e-224 707.0
PYH1_k127_3366868_6 PFAM CHAD domain containing protein - - - 7.627e-223 703.0
PYH1_k127_3366868_7 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 622.0
PYH1_k127_3366868_8 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 515.0
PYH1_k127_3366868_9 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 524.0
PYH1_k127_3384772_0 - - - - 0.000000000000000000000000000000000000000000000000001224 188.0
PYH1_k127_3384772_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000153 143.0
PYH1_k127_3384772_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000001047 107.0
PYH1_k127_3413966_0 peptidoglycan turnover - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001764 281.0
PYH1_k127_3413966_1 N-4 methylation of cytosine K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000007457 211.0
PYH1_k127_3413966_2 carboxylic ester hydrolase activity - - - 0.00000000000005415 74.0
PYH1_k127_3417687_0 mechanosensitive ion channel - - - 1.737e-220 689.0
PYH1_k127_3417687_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 539.0
PYH1_k127_3417687_2 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
PYH1_k127_3417687_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000000002411 162.0
PYH1_k127_3417687_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000000001211 114.0
PYH1_k127_3417687_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000006338 65.0
PYH1_k127_3420088_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 319.0
PYH1_k127_3444614_0 Pfam Aminotransferase class I and II K14267 - 2.6.1.17 3.947e-268 826.0
PYH1_k127_3444614_1 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 558.0
PYH1_k127_3444614_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 503.0
PYH1_k127_3444614_3 Atypical PilZ domain, cyclic di-GMP receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 319.0
PYH1_k127_3444614_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001258 232.0
PYH1_k127_3444614_5 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000006906 166.0
PYH1_k127_3448179_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 1.943e-261 807.0
PYH1_k127_3448179_1 Uncharacterised protein family (UPF0160) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 569.0
PYH1_k127_3448179_10 Cupredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000002632 178.0
PYH1_k127_3448179_11 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000001914 173.0
PYH1_k127_3448179_12 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000000000000004248 137.0
PYH1_k127_3448179_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 531.0
PYH1_k127_3448179_3 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 489.0
PYH1_k127_3448179_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 436.0
PYH1_k127_3448179_5 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 434.0
PYH1_k127_3448179_6 Psort location CytoplasmicMembrane, score K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 422.0
PYH1_k127_3448179_8 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 389.0
PYH1_k127_3448179_9 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000368 211.0
PYH1_k127_34593_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1533.0
PYH1_k127_34593_1 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1397.0
PYH1_k127_34593_10 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 332.0
PYH1_k127_34593_11 Sterol-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 291.0
PYH1_k127_34593_12 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361 282.0
PYH1_k127_34593_13 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
PYH1_k127_34593_14 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001116 209.0
PYH1_k127_34593_15 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000001219 204.0
PYH1_k127_34593_16 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000006926 191.0
PYH1_k127_34593_17 Ferredoxin-type protein NapF K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000001893 184.0
PYH1_k127_34593_18 - - - - 0.00000000000000000000000000000000003773 136.0
PYH1_k127_34593_19 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000000000000000007199 129.0
PYH1_k127_34593_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 9.608e-320 980.0
PYH1_k127_34593_20 CRP FNR family K21563 - - 0.000000005406 57.0
PYH1_k127_34593_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 2.76e-295 909.0
PYH1_k127_34593_4 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 2.136e-267 824.0
PYH1_k127_34593_5 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 573.0
PYH1_k127_34593_6 PFAM RIO-like kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 538.0
PYH1_k127_34593_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 436.0
PYH1_k127_34593_8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 424.0
PYH1_k127_34593_9 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 401.0
PYH1_k127_3533065_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004848 273.0
PYH1_k127_3537925_0 Polysaccharide chain length determinant protein - - - 2.319e-274 850.0
PYH1_k127_3537925_1 Protein conserved in bacteria - - - 2.173e-272 845.0
PYH1_k127_3537925_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 1.705e-228 709.0
PYH1_k127_3537925_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 2.579e-222 692.0
PYH1_k127_3537925_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 8.705e-220 683.0
PYH1_k127_3537925_5 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 590.0
PYH1_k127_3537925_6 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
PYH1_k127_3537925_7 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 364.0
PYH1_k127_3537925_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 321.0
PYH1_k127_3537925_9 AAA domain K08252,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
PYH1_k127_3553882_0 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 429.0
PYH1_k127_3553882_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 291.0
PYH1_k127_3553882_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000001134 158.0
PYH1_k127_3576989_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 8.208e-259 800.0
PYH1_k127_3576989_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 482.0
PYH1_k127_3576989_2 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 282.0
PYH1_k127_3576989_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004653 267.0
PYH1_k127_3576989_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000007678 66.0
PYH1_k127_3648402_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 2.905e-252 798.0
PYH1_k127_3648402_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 554.0
PYH1_k127_3648402_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 361.0
PYH1_k127_3648402_3 Domain of unknown function (DUF1854) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 273.0
PYH1_k127_3648402_4 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003685 244.0
PYH1_k127_3648402_5 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.000000000000000000000000000000000009134 136.0
PYH1_k127_3650426_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.574e-270 831.0
PYH1_k127_3650426_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.041e-217 676.0
PYH1_k127_3650426_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 422.0
PYH1_k127_3650426_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000001538 156.0
PYH1_k127_3676971_0 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 340.0
PYH1_k127_3676971_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 307.0
PYH1_k127_3676971_2 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000000000000000000000001864 172.0
PYH1_k127_3676971_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000124 76.0
PYH1_k127_3687370_0 pyridine - - - 1.002e-270 835.0
PYH1_k127_3687370_1 Belongs to the methyltransferase superfamily K07444 - - 7.796e-232 725.0
PYH1_k127_3687370_10 Serine aminopeptidase, S33 K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000004572 234.0
PYH1_k127_3687370_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005584 226.0
PYH1_k127_3687370_12 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000002958 194.0
PYH1_k127_3687370_13 Stress responsive alpha-beta barrel - - - 0.00000000000000000000000000000000000000000000000000001978 188.0
PYH1_k127_3687370_14 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000000000000000007067 163.0
PYH1_k127_3687370_15 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000005703 158.0
PYH1_k127_3687370_16 Transcriptional regulator - - - 0.00000000000000000000000000000000004084 134.0
PYH1_k127_3687370_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 2.911e-200 627.0
PYH1_k127_3687370_3 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 5.072e-194 605.0
PYH1_k127_3687370_4 Aminotransferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 526.0
PYH1_k127_3687370_5 Transport permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 492.0
PYH1_k127_3687370_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 389.0
PYH1_k127_3687370_7 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 364.0
PYH1_k127_3687370_8 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 315.0
PYH1_k127_3687370_9 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 282.0
PYH1_k127_372926_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 526.0
PYH1_k127_372926_1 RNA polymerase sigma factor RpoS K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 418.0
PYH1_k127_372926_2 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 404.0
PYH1_k127_372926_3 TIGRFAM outer membrane adhesin like proteiin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 347.0
PYH1_k127_372926_4 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
PYH1_k127_372926_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000288 198.0
PYH1_k127_372926_6 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K20276 - 3.4.24.40 0.00000000000002655 87.0
PYH1_k127_3742013_0 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 3.672e-261 815.0
PYH1_k127_3742013_1 PFAM Prenyltransferase squalene oxidase - - - 5.129e-251 778.0
PYH1_k127_3742013_10 Formyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 343.0
PYH1_k127_3742013_2 Wzy family polymerase, exosortase system type 1 associated - - - 3.368e-238 741.0
PYH1_k127_3742013_3 glycosyl transferase group 1 - - - 3.706e-229 715.0
PYH1_k127_3742013_4 - - - - 1.092e-209 656.0
PYH1_k127_3742013_5 Glycosyl transferases group 1 - - - 8.064e-202 632.0
PYH1_k127_3742013_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 577.0
PYH1_k127_3742013_7 Glycosyl transferase 4-like domain K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 544.0
PYH1_k127_3742013_8 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 531.0
PYH1_k127_3742013_9 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 413.0
PYH1_k127_3757559_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 2231.0
PYH1_k127_3757559_1 similarity to GP 17427840 K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 455.0
PYH1_k127_3757559_2 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 299.0
PYH1_k127_3757559_3 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001264 235.0
PYH1_k127_3757559_4 TIGRFAM yecA family protein K07039 - - 0.00000000000000000000000000000000001027 140.0
PYH1_k127_3757559_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000009974 104.0
PYH1_k127_3757559_6 - - - - 0.0000006868 51.0
PYH1_k127_3804177_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.377e-208 647.0
PYH1_k127_382766_0 Carboxypeptidase regulatory-like domain - - - 4.538e-236 749.0
PYH1_k127_3925684_0 Dynamin family - - - 0.0 1221.0
PYH1_k127_3925684_1 Belongs to the peptidase M16 family K07263 - - 8.385e-272 843.0
PYH1_k127_3925684_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 580.0
PYH1_k127_3925684_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 540.0
PYH1_k127_3925684_4 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 522.0
PYH1_k127_3925684_5 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 422.0
PYH1_k127_3925684_6 methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
PYH1_k127_3925684_7 Cell division ATP-binding protein ftsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 362.0
PYH1_k127_3925684_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
PYH1_k127_3925684_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000522 179.0
PYH1_k127_3970591_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003162 266.0
PYH1_k127_3970591_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004431 250.0
PYH1_k127_3970591_2 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000005975 132.0
PYH1_k127_3970591_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479,K07692 - - 0.0000000000000001869 85.0
PYH1_k127_3986498_0 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 518.0
PYH1_k127_3986498_1 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 423.0
PYH1_k127_3986498_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001529 269.0
PYH1_k127_3986498_3 Phosphate-starvation-inducible E K13256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006729 244.0
PYH1_k127_3986498_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000007828 210.0
PYH1_k127_3986498_5 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000004343 145.0
PYH1_k127_3986498_6 ketose-bisphosphate aldolase K01624 - 4.1.2.13 0.0000000000000000000000000000000007973 131.0
PYH1_k127_4040727_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 374.0
PYH1_k127_4040727_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 351.0
PYH1_k127_4040727_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
PYH1_k127_4049596_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2306.0
PYH1_k127_4049596_1 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 1.752e-314 965.0
PYH1_k127_4049596_2 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 494.0
PYH1_k127_4049596_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 508.0
PYH1_k127_4049596_4 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 336.0
PYH1_k127_4049596_5 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
PYH1_k127_4049596_6 Nitrate reductase K00373 - - 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
PYH1_k127_4049596_7 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000005164 173.0
PYH1_k127_4049596_8 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000001061 165.0
PYH1_k127_4049596_9 PFAM cytochrome c, class I K08738 - - 0.000000000000000000361 93.0
PYH1_k127_4076202_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 3.252e-277 854.0
PYH1_k127_4076202_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 467.0
PYH1_k127_4076202_2 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 425.0
PYH1_k127_4076202_3 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 410.0
PYH1_k127_4076202_4 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000158 243.0
PYH1_k127_4076202_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000001047 188.0
PYH1_k127_4086340_0 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 388.0
PYH1_k127_4086340_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 356.0
PYH1_k127_4086340_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 325.0
PYH1_k127_4086340_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007385 247.0
PYH1_k127_4086340_4 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000000000000000000000000000000000000000000000006327 190.0
PYH1_k127_4086340_6 - - - - 0.000000000000000764 81.0
PYH1_k127_4155134_0 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 563.0
PYH1_k127_4155134_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 545.0
PYH1_k127_4155134_2 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000166 220.0
PYH1_k127_415896_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002568 243.0
PYH1_k127_415896_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000001728 173.0
PYH1_k127_415896_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000001289 172.0
PYH1_k127_415896_3 transferase activity, transferring glycosyl groups - - - 0.0000000000001259 77.0
PYH1_k127_4204612_0 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 409.0
PYH1_k127_4204612_1 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 402.0
PYH1_k127_4204612_2 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004182 248.0
PYH1_k127_4256084_0 Histidine kinase K20974 - 2.7.13.3 4.702e-214 686.0
PYH1_k127_4258159_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1079.0
PYH1_k127_4258159_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.373e-270 834.0
PYH1_k127_4258159_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008536 274.0
PYH1_k127_4258159_11 YqeY-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
PYH1_k127_4258159_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000000000002058 230.0
PYH1_k127_4258159_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000000000000005476 224.0
PYH1_k127_4258159_14 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000000242 158.0
PYH1_k127_4258159_15 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000000006324 136.0
PYH1_k127_4258159_16 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000004 111.0
PYH1_k127_4258159_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 6.717e-204 637.0
PYH1_k127_4258159_3 Tyrosine recombinase xerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 570.0
PYH1_k127_4258159_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 502.0
PYH1_k127_4258159_5 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 493.0
PYH1_k127_4258159_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 378.0
PYH1_k127_4258159_7 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 358.0
PYH1_k127_4258159_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 342.0
PYH1_k127_4258159_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001711 279.0
PYH1_k127_426278_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.513e-286 878.0
PYH1_k127_426278_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000003506 256.0
PYH1_k127_426278_2 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.00000000000000000000000007054 107.0
PYH1_k127_4266995_0 ribonuclease, Rne Rng family K08301 - - 3.383e-283 871.0
PYH1_k127_4266995_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.336e-250 774.0
PYH1_k127_4266995_10 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 554.0
PYH1_k127_4266995_11 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 551.0
PYH1_k127_4266995_12 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 561.0
PYH1_k127_4266995_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 528.0
PYH1_k127_4266995_14 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 503.0
PYH1_k127_4266995_15 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 458.0
PYH1_k127_4266995_16 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 447.0
PYH1_k127_4266995_17 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 449.0
PYH1_k127_4266995_18 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 417.0
PYH1_k127_4266995_19 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 414.0
PYH1_k127_4266995_2 phosphate-selective porin O and P - - - 1.519e-249 775.0
PYH1_k127_4266995_20 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 383.0
PYH1_k127_4266995_21 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 351.0
PYH1_k127_4266995_22 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 321.0
PYH1_k127_4266995_23 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000002745 220.0
PYH1_k127_4266995_24 coa-binding K06929 - - 0.000000000000000000000000000000000000000000000000000163 189.0
PYH1_k127_4266995_25 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000007356 169.0
PYH1_k127_4266995_27 - - - - 0.000000000000000000000000000000000006218 141.0
PYH1_k127_4266995_28 PEP-CTERM motif - - - 0.0000000000000000000000000000000001132 141.0
PYH1_k127_4266995_29 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000001636 127.0
PYH1_k127_4266995_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.544e-247 771.0
PYH1_k127_4266995_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.95e-243 754.0
PYH1_k127_4266995_5 Pfam Major Facilitator Superfamily - - - 8.354e-240 745.0
PYH1_k127_4266995_6 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 597.0
PYH1_k127_4266995_7 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 580.0
PYH1_k127_4266995_8 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 576.0
PYH1_k127_4266995_9 Periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 557.0
PYH1_k127_4281114_0 Peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 522.0
PYH1_k127_4281114_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 536.0
PYH1_k127_4281114_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 306.0
PYH1_k127_4281114_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001829 283.0
PYH1_k127_4281114_4 - - - - 0.0000000000000000000000000000000000000000000000000000005106 194.0
PYH1_k127_4281114_5 DsrE/DsrF-like family K06039 - - 0.00000000000000000000001203 104.0
PYH1_k127_4313962_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 3.339e-242 748.0
PYH1_k127_4313962_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 519.0
PYH1_k127_4313962_2 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000001151 233.0
PYH1_k127_4315795_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 367.0
PYH1_k127_4315795_1 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005257 275.0
PYH1_k127_4331172_0 trisaccharide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009216 296.0
PYH1_k127_4331172_1 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000005575 162.0
PYH1_k127_4346230_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 4.457e-218 679.0
PYH1_k127_4346230_1 chorismate mutase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 329.0
PYH1_k127_4346230_2 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000006952 163.0
PYH1_k127_4397079_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 531.0
PYH1_k127_4397079_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 515.0
PYH1_k127_4397079_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 428.0
PYH1_k127_4397079_3 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000007207 121.0
PYH1_k127_4397121_0 Heavy metal translocating P-type atpase K01533 - 3.6.3.4 0.0 1490.0
PYH1_k127_4397121_1 Cytochrome c oxidase accessory protein ccog - - - 1.531e-297 917.0
PYH1_k127_4397121_10 Cbb3-type cytochrome oxidase component FixQ - - - 0.0000000000000000000000001865 107.0
PYH1_k127_4397121_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 591.0
PYH1_k127_4397121_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 532.0
PYH1_k127_4397121_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 515.0
PYH1_k127_4397121_5 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 488.0
PYH1_k127_4397121_6 cytochrome c oxidase cbb3-type, subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 481.0
PYH1_k127_4397121_7 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 479.0
PYH1_k127_4397121_8 Cell division ATP-binding protein ftsE K09812 - - 0.000000000000000000000000000000001397 130.0
PYH1_k127_4397121_9 Cytochrome oxidase maturation protein - - - 0.000000000000000000000000004843 115.0
PYH1_k127_4400802_0 Transport permease protein K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 512.0
PYH1_k127_4400802_1 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 454.0
PYH1_k127_4400802_2 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 320.0
PYH1_k127_4400802_3 abc transporter K09691 - - 0.00000000000000000000000000000000000000000001311 163.0
PYH1_k127_4439559_0 von Willebrand factor, type A - - - 1.871e-281 869.0
PYH1_k127_4439559_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.124e-196 612.0
PYH1_k127_4439559_2 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 509.0
PYH1_k127_4445328_0 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 597.0
PYH1_k127_4445328_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 538.0
PYH1_k127_4445328_2 hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 511.0
PYH1_k127_4445328_3 orn lys arg decarboxylase K01584 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 507.0
PYH1_k127_4445328_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 314.0
PYH1_k127_4445328_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000003067 170.0
PYH1_k127_4465502_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 398.0
PYH1_k127_4465502_1 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 309.0
PYH1_k127_4465502_2 PFAM ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000004283 147.0
PYH1_k127_4465502_3 - - - - 0.000000005576 63.0
PYH1_k127_4501279_0 GTP-binding protein TypA K06207 - - 0.0 1181.0
PYH1_k127_4501279_1 protein conserved in bacteria K09760 - - 3.335e-264 816.0
PYH1_k127_4501279_2 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 1.582e-209 662.0
PYH1_k127_4501279_4 Diguanylate cyclase K03320 - - 0.000000000000000000001032 96.0
PYH1_k127_450267_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 458.0
PYH1_k127_450267_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003291 240.0
PYH1_k127_450267_2 - - - - 0.000000000000000000000000000000000000000000000000001654 183.0
PYH1_k127_450267_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001098 184.0
PYH1_k127_450267_5 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000000007883 152.0
PYH1_k127_450267_6 Glyoxalase-like domain - - - 0.00000000000000000000000000000002823 129.0
PYH1_k127_450267_7 Transcriptional regulator, Crp Fnr family - - - 0.0000001155 56.0
PYH1_k127_4502937_0 alcohol dehydrogenase K00001 - 1.1.1.1 3.479e-236 732.0
PYH1_k127_4502937_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 509.0
PYH1_k127_4502937_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 334.0
PYH1_k127_4502937_3 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000001884 197.0
PYH1_k127_4502937_4 Extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000001308 180.0
PYH1_k127_4516506_0 Ornithine-acyl acyl carrier protein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 479.0
PYH1_k127_4516506_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 427.0
PYH1_k127_4516506_2 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000003544 204.0
PYH1_k127_4516506_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000001162 187.0
PYH1_k127_4532394_0 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 4.82e-244 755.0
PYH1_k127_4532394_1 Abc transporter K06147 - - 2.015e-212 661.0
PYH1_k127_4532394_2 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 565.0
PYH1_k127_4532394_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 286.0
PYH1_k127_4532394_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001287 275.0
PYH1_k127_4532394_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000001096 147.0
PYH1_k127_4532394_6 Cold shock protein K03704 - - 0.0000000000000000000000000000000000002803 140.0
PYH1_k127_4532394_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000009478 77.0
PYH1_k127_4535126_0 4Fe-4S dicluster domain K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 559.0
PYH1_k127_4535126_1 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 519.0
PYH1_k127_4535126_2 Cytochrome d1, heme K15864 - 1.7.2.1,1.7.99.1 0.00000000000000000000000000000000000000000003796 162.0
PYH1_k127_4535126_3 NapD protein K02570 - - 0.00000000000000000000000000002342 119.0
PYH1_k127_4535126_4 Flagellar Assembly Protein A K09749 - - 0.0000000000000000301 90.0
PYH1_k127_461620_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 2.251e-206 643.0
PYH1_k127_461620_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 568.0
PYH1_k127_461620_2 - - - - 0.00000004551 55.0
PYH1_k127_461919_0 peptidase U62, modulator of DNA gyrase K03592 - - 1.103e-230 715.0
PYH1_k127_461919_1 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH1_k127_4621710_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 9.321e-229 709.0
PYH1_k127_4621710_1 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000007548 127.0
PYH1_k127_4621710_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000001026 59.0
PYH1_k127_4639503_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 2.635e-262 811.0
PYH1_k127_4639503_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 8.301e-255 786.0
PYH1_k127_4639503_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.065e-216 677.0
PYH1_k127_4639503_3 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 474.0
PYH1_k127_4639503_4 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 333.0
PYH1_k127_4639503_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006105 270.0
PYH1_k127_4639503_6 iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000001372 224.0
PYH1_k127_4639503_7 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000000000000004491 219.0
PYH1_k127_4646228_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 3038.0
PYH1_k127_4646228_1 COG0457 FOG TPR repeat - - - 0.0 1489.0
PYH1_k127_4646228_10 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 522.0
PYH1_k127_4646228_11 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 530.0
PYH1_k127_4646228_12 lytic transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 496.0
PYH1_k127_4646228_13 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 473.0
PYH1_k127_4646228_14 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 462.0
PYH1_k127_4646228_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 372.0
PYH1_k127_4646228_16 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 348.0
PYH1_k127_4646228_17 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001308 248.0
PYH1_k127_4646228_18 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005087 233.0
PYH1_k127_4646228_19 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000002858 218.0
PYH1_k127_4646228_2 Histidine kinase - - - 0.0 1230.0
PYH1_k127_4646228_20 PEP-CTERM motif - - - 0.000000000000000000000000246 115.0
PYH1_k127_4646228_21 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000009077 83.0
PYH1_k127_4646228_22 PFAM Transposase IS200 like - - - 0.00004934 48.0
PYH1_k127_4646228_3 COG0457 FOG TPR repeat - - - 0.0 1202.0
PYH1_k127_4646228_4 Heparinase II/III-like protein - - - 0.0 1186.0
PYH1_k127_4646228_5 Asparagine synthase K01953 - 6.3.5.4 0.0 1077.0
PYH1_k127_4646228_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 1.166e-277 868.0
PYH1_k127_4646228_7 response regulator K02481,K10941 - - 3.766e-260 806.0
PYH1_k127_4646228_8 Sugar transferase K21303 - 2.7.8.40 2.138e-252 783.0
PYH1_k127_4646228_9 UDP binding domain K02474 - - 2.64e-231 722.0
PYH1_k127_4775987_0 HPr kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 583.0
PYH1_k127_4775987_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 551.0
PYH1_k127_4775987_2 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 317.0
PYH1_k127_4775987_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 294.0
PYH1_k127_4775987_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004536 265.0
PYH1_k127_4775987_5 Autotransporter beta-domain K12685 - - 0.00000000000000000000000000000000000000000001453 171.0
PYH1_k127_4775987_6 - - - - 0.000000000000000000000000000000000000000002346 157.0
PYH1_k127_4793688_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1328.0
PYH1_k127_4816484_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002861 273.0
PYH1_k127_4816484_1 transposase - - - 0.00000000000000000000000000000000000001356 149.0
PYH1_k127_4816484_2 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000000000415 130.0
PYH1_k127_4816484_3 Belongs to the 'phage' integrase family K04763 - - 0.000002395 51.0
PYH1_k127_4825123_0 type II and III secretion system protein K02453,K12282 - - 0.0 1081.0
PYH1_k127_4825123_1 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1056.0
PYH1_k127_4825123_10 Prokaryotic N-terminal methylation motif K10924 - - 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
PYH1_k127_4825123_11 - K12281 - - 0.0000000000000000000000000000000000000000000000008949 177.0
PYH1_k127_4825123_12 Pilus assembly protein PilX K12286 - - 0.000000000000000000000000000000000000000000000001431 179.0
PYH1_k127_4825123_13 Tfp pilus assembly protein FimT K10926 - - 0.00000000000000000000000000000000000000000000003957 173.0
PYH1_k127_4825123_14 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000000000000000003515 156.0
PYH1_k127_4825123_15 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000000000007146 123.0
PYH1_k127_4825123_2 Type II secretion system K02455,K12278 - - 3.785e-232 722.0
PYH1_k127_4825123_3 PFAM Fimbrial assembly family protein K12279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 516.0
PYH1_k127_4825123_4 Prokaryotic N-terminal methylation motif K12285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 456.0
PYH1_k127_4825123_5 AAA domain K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 417.0
PYH1_k127_4825123_6 Conserved repeat domain K12287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 417.0
PYH1_k127_4825123_7 carbon utilization K12280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 361.0
PYH1_k127_4825123_8 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 331.0
PYH1_k127_4825123_9 PFAM Fimbrial assembly family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 329.0
PYH1_k127_483500_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.193e-316 970.0
PYH1_k127_483500_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 504.0
PYH1_k127_483500_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 437.0
PYH1_k127_483500_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001658 200.0
PYH1_k127_485336_0 EAL domain - - - 0.0 1244.0
PYH1_k127_485336_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.86e-293 902.0
PYH1_k127_485336_10 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000000002807 158.0
PYH1_k127_485336_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000007956 130.0
PYH1_k127_485336_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 3.072e-255 790.0
PYH1_k127_485336_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 2.831e-231 719.0
PYH1_k127_485336_4 - - - - 1.37e-225 702.0
PYH1_k127_485336_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.334e-221 686.0
PYH1_k127_485336_6 Type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 465.0
PYH1_k127_485336_7 Transcriptional regulator K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 451.0
PYH1_k127_485336_8 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
PYH1_k127_485336_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000002676 202.0
PYH1_k127_4865543_0 chemotaxis K03406 - - 1.18e-315 974.0
PYH1_k127_4865543_1 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 392.0
PYH1_k127_4865543_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 382.0
PYH1_k127_4865543_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 370.0
PYH1_k127_4865543_4 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000396 220.0
PYH1_k127_4885428_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1173.0
PYH1_k127_4885428_1 SMART AAA ATPase K02450 - - 5.097e-295 911.0
PYH1_k127_4885428_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 527.0
PYH1_k127_4885428_3 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 491.0
PYH1_k127_4885428_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 402.0
PYH1_k127_4885428_5 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 395.0
PYH1_k127_4885428_6 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000000000000000006094 218.0
PYH1_k127_4885428_7 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000000000000000001362 201.0
PYH1_k127_4885428_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000000000000000004659 153.0
PYH1_k127_4912201_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 475.0
PYH1_k127_4912201_1 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004825 294.0
PYH1_k127_4912201_2 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.000000000000000000000000000000000000000000000000000006298 200.0
PYH1_k127_4912201_3 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000003392 121.0
PYH1_k127_4912201_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000001316 116.0
PYH1_k127_4912201_5 - - - - 0.0000000000000009141 79.0
PYH1_k127_4912201_6 aminopeptidase activity K09612,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.10,3.4.11.24,3.4.11.6 0.000006218 55.0
PYH1_k127_4912201_7 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.00005441 46.0
PYH1_k127_4963178_0 PFAM Sulfatase K01130 - 3.1.6.1 1.075e-195 623.0
PYH1_k127_4963178_1 PFAM peptidase M28 - - - 0.0000000000000000000007096 100.0
PYH1_k127_5021882_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1273.0
PYH1_k127_5021882_1 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 460.0
PYH1_k127_5021882_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 346.0
PYH1_k127_5021882_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 340.0
PYH1_k127_5039803_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1476.0
PYH1_k127_5039803_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1089.0
PYH1_k127_5039803_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.143e-268 830.0
PYH1_k127_5039803_3 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 565.0
PYH1_k127_5046009_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 582.0
PYH1_k127_5046009_1 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 538.0
PYH1_k127_5046009_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 516.0
PYH1_k127_5046009_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000006104 166.0
PYH1_k127_5046009_4 - - - - 0.000000000000000000000000000000000001806 139.0
PYH1_k127_5098537_0 Dimerisation domain - - - 1.973e-205 646.0
PYH1_k127_5098537_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 474.0
PYH1_k127_5098537_2 Cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 368.0
PYH1_k127_5098537_3 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
PYH1_k127_5098537_4 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
PYH1_k127_5098537_5 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001225 244.0
PYH1_k127_5098537_6 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004159 239.0
PYH1_k127_5098537_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000008789 201.0
PYH1_k127_5100458_0 histidine kinase A domain protein K07679 - 2.7.13.3 1.435e-216 708.0
PYH1_k127_5100458_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0002003 45.0
PYH1_k127_5108388_0 ABC transporter transmembrane region K12541 - - 1.613e-292 914.0
PYH1_k127_5108388_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 5.26e-233 726.0
PYH1_k127_5108388_2 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 1.205e-225 703.0
PYH1_k127_5108388_3 endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 499.0
PYH1_k127_5108388_4 type I secretion membrane fusion protein, HlyD family K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 480.0
PYH1_k127_5108388_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 429.0
PYH1_k127_5108388_6 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 289.0
PYH1_k127_5108388_7 tryptophan synthase subunit beta - - - 0.0000000000000000004419 91.0
PYH1_k127_512388_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.416e-212 659.0
PYH1_k127_512388_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 421.0
PYH1_k127_512388_2 response to toxic substance K16347,K16348 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000002636 56.0
PYH1_k127_5131239_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 2.527e-256 792.0
PYH1_k127_5131239_1 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 8.863e-245 762.0
PYH1_k127_5131239_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 3.593e-221 687.0
PYH1_k127_5131239_3 Diguanylate cyclase K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 579.0
PYH1_k127_5131239_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 331.0
PYH1_k127_5131239_5 response regulator K02483,K07666 - - 0.000000000000000000000000000000000000000000000000267 176.0
PYH1_k127_5131239_6 - - - - 0.00000009169 56.0
PYH1_k127_5138247_0 AMP-binding enzyme C-terminal domain K00666 - - 2.548e-272 850.0
PYH1_k127_5138247_1 PFAM EAL domain protein - - - 1.687e-207 651.0
PYH1_k127_5138247_10 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 366.0
PYH1_k127_5138247_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005772 265.0
PYH1_k127_5138247_12 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000005925 162.0
PYH1_k127_5138247_13 THUMP - - - 0.0000000000000000000000000000000000004824 146.0
PYH1_k127_5138247_14 - - - - 0.000000000000000000000000000000000004179 143.0
PYH1_k127_5138247_15 PFAM ThiJ PfpI K05520 - 3.5.1.124 0.000003815 50.0
PYH1_k127_5138247_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 581.0
PYH1_k127_5138247_3 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 559.0
PYH1_k127_5138247_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 466.0
PYH1_k127_5138247_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 466.0
PYH1_k127_5138247_6 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
PYH1_k127_5138247_7 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
PYH1_k127_5138247_8 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 384.0
PYH1_k127_5138247_9 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 359.0
PYH1_k127_5162677_0 Nitric oxide reductase K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 540.0
PYH1_k127_5162677_1 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 523.0
PYH1_k127_5162677_2 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 369.0
PYH1_k127_5162677_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008211 231.0
PYH1_k127_5162677_4 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000000000000000000000000000000000000000000000001287 177.0
PYH1_k127_5162677_5 - - - - 0.0000000000000000000000000000001342 128.0
PYH1_k127_5171192_0 diguanylate cyclase - - - 0.0 1133.0
PYH1_k127_5171192_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 484.0
PYH1_k127_5171192_2 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 439.0
PYH1_k127_5171192_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000009989 167.0
PYH1_k127_5185355_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 495.0
PYH1_k127_5185355_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000001243 62.0
PYH1_k127_5191415_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1088.0
PYH1_k127_5191415_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 299.0
PYH1_k127_5191415_2 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000000000000000000000000000000000000000000181 216.0
PYH1_k127_5191415_3 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000000000000000000000000000001286 195.0
PYH1_k127_5191415_4 YqjK-like protein - - - 0.000000000003527 70.0
PYH1_k127_5215683_0 PFAM ABC-1 domain protein K03688 - - 0.0 1045.0
PYH1_k127_5215683_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.632e-260 804.0
PYH1_k127_5215683_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 375.0
PYH1_k127_5215743_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001754 241.0
PYH1_k127_5215743_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000002206 239.0
PYH1_k127_5215743_2 response regulator receiver K07814 - - 0.000000002715 58.0
PYH1_k127_5226343_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004625 281.0
PYH1_k127_5226343_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001005 212.0
PYH1_k127_5228605_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 535.0
PYH1_k127_5228605_1 UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 470.0
PYH1_k127_5228605_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 433.0
PYH1_k127_5228605_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000003456 203.0
PYH1_k127_5228605_4 PFAM TatD-related deoxyribonuclease K03424 - - 0.0000000000000000000000000000000000000007295 148.0
PYH1_k127_5228605_5 - - - - 0.0000000000000000000000000000236 120.0
PYH1_k127_524820_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000005081 161.0
PYH1_k127_524820_1 IMG reference gene - - - 0.0000000000000000000006779 110.0
PYH1_k127_5255336_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0 1061.0
PYH1_k127_5255336_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00005127 46.0
PYH1_k127_5258431_0 Nad-dependent epimerase dehydratase - - - 7.504e-227 703.0
PYH1_k127_5258431_1 polysaccharide deacetylase - - - 8.004e-195 609.0
PYH1_k127_5258431_2 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 585.0
PYH1_k127_5258431_3 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 388.0
PYH1_k127_5258431_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002221 277.0
PYH1_k127_5261241_0 malic enzyme K00029 - 1.1.1.40 3.002e-244 756.0
PYH1_k127_5261241_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 371.0
PYH1_k127_5261241_2 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000000000000000000000004236 197.0
PYH1_k127_5261241_3 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000000000000000001988 167.0
PYH1_k127_5301321_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1549.0
PYH1_k127_5301321_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1495.0
PYH1_k127_5301321_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.873e-293 900.0
PYH1_k127_5301321_11 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.297e-278 857.0
PYH1_k127_5301321_12 Belongs to the GARS family K01945 - 6.3.4.13 1.985e-269 830.0
PYH1_k127_5301321_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 5.649e-254 785.0
PYH1_k127_5301321_14 response regulator - - - 7.832e-244 756.0
PYH1_k127_5301321_15 Amino acid permease K03294 - - 4.116e-226 707.0
PYH1_k127_5301321_16 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 8.847e-213 664.0
PYH1_k127_5301321_17 PFAM Peptidoglycan-binding LysM - - - 4.901e-212 660.0
PYH1_k127_5301321_18 DNA protecting protein DprA K04096 - - 2.557e-206 644.0
PYH1_k127_5301321_19 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 2.842e-201 631.0
PYH1_k127_5301321_2 Histidine kinase - - - 0.0 1246.0
PYH1_k127_5301321_20 - - - - 7.251e-198 619.0
PYH1_k127_5301321_21 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 558.0
PYH1_k127_5301321_22 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 545.0
PYH1_k127_5301321_23 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 541.0
PYH1_k127_5301321_24 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 530.0
PYH1_k127_5301321_25 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 525.0
PYH1_k127_5301321_26 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 521.0
PYH1_k127_5301321_27 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 496.0
PYH1_k127_5301321_28 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 492.0
PYH1_k127_5301321_29 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 489.0
PYH1_k127_5301321_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1224.0
PYH1_k127_5301321_30 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 452.0
PYH1_k127_5301321_31 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 433.0
PYH1_k127_5301321_32 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 410.0
PYH1_k127_5301321_33 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 376.0
PYH1_k127_5301321_34 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 373.0
PYH1_k127_5301321_35 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 368.0
PYH1_k127_5301321_36 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
PYH1_k127_5301321_37 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 318.0
PYH1_k127_5301321_38 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 312.0
PYH1_k127_5301321_39 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 299.0
PYH1_k127_5301321_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1202.0
PYH1_k127_5301321_40 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 279.0
PYH1_k127_5301321_41 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002318 262.0
PYH1_k127_5301321_42 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 246.0
PYH1_k127_5301321_43 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
PYH1_k127_5301321_44 ATP synthase I chain K02116 - - 0.0000000000000000000000000000000000000000000000000000003359 196.0
PYH1_k127_5301321_45 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000009626 143.0
PYH1_k127_5301321_46 PFAM cytochrome c, class I K08738 - - 0.000000000000000000000000000000008676 129.0
PYH1_k127_5301321_47 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000001717 121.0
PYH1_k127_5301321_48 VanZ like family - - - 0.00000000000000000000031 106.0
PYH1_k127_5301321_49 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000001925 91.0
PYH1_k127_5301321_5 Transport of potassium into the cell K03549 - - 0.0 1190.0
PYH1_k127_5301321_50 Selenoprotein, putative - - - 0.000000000000000002196 86.0
PYH1_k127_5301321_51 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002395 79.0
PYH1_k127_5301321_52 Protein of unknown function, DUF255 K06888 - - 0.00000000000008267 75.0
PYH1_k127_5301321_53 Protein of unknown function, DUF255 K06888 - - 0.000000001578 58.0
PYH1_k127_5301321_54 Protein of unknown function, DUF255 K06888 - - 0.000000002561 58.0
PYH1_k127_5301321_55 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000004739 63.0
PYH1_k127_5301321_56 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000008318 59.0
PYH1_k127_5301321_6 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1141.0
PYH1_k127_5301321_7 PFAM Carbon starvation protein CstA K06200 - - 0.0 1138.0
PYH1_k127_5301321_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0 998.0
PYH1_k127_5301321_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.191e-320 984.0
PYH1_k127_5306059_0 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 577.0
PYH1_k127_5306059_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 494.0
PYH1_k127_5329538_0 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 376.0
PYH1_k127_5329538_1 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 335.0
PYH1_k127_5329538_2 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 283.0
PYH1_k127_5329538_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000004785 48.0
PYH1_k127_535224_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 1.605e-221 689.0
PYH1_k127_535224_1 permease - - - 1.777e-203 638.0
PYH1_k127_535224_2 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 299.0
PYH1_k127_535224_3 Protein of unknown function (DUF3301) - - - 0.00000000000000000000000000000000000000000000000000000000000001894 215.0
PYH1_k127_535224_4 Cold shock protein K03704 - - 0.000000000000000000000000000000000000688 141.0
PYH1_k127_5360887_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.919e-272 845.0
PYH1_k127_5360887_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.206e-259 804.0
PYH1_k127_5360887_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 2.879e-232 722.0
PYH1_k127_5360887_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 5.401e-221 691.0
PYH1_k127_5360887_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 1.234e-215 672.0
PYH1_k127_5360887_5 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 486.0
PYH1_k127_5360887_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 425.0
PYH1_k127_5424290_0 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1007.0
PYH1_k127_5424290_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 594.0
PYH1_k127_5424290_2 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004065 266.0
PYH1_k127_5426177_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1379.0
PYH1_k127_5426177_1 Outer membrane efflux protein - - - 1.013e-222 699.0
PYH1_k127_5426177_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 376.0
PYH1_k127_5426177_3 Protein of unknown function (DUF3240) - - - 0.000000000000000000000000000000000000000000000000000000009552 198.0
PYH1_k127_5443_0 Diguanylate cyclase - - - 0.0 1031.0
PYH1_k127_5443_1 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000001987 192.0
PYH1_k127_5443_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000001624 109.0
PYH1_k127_5467730_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2446.0
PYH1_k127_5467730_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1339.0
PYH1_k127_5467730_10 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000000000000000000000001923 171.0
PYH1_k127_5467730_11 response regulator - - - 0.0000000000000000000000000000000000000000000001197 169.0
PYH1_k127_5467730_12 PFAM CcdB protein K19163 - - 0.000000000000000000000000000000000005278 139.0
PYH1_k127_5467730_13 Post-segregation antitoxin CcdA K19164 - - 0.00000000000000000000002162 101.0
PYH1_k127_5467730_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 3.918e-263 811.0
PYH1_k127_5467730_3 SMART phosphoesterase PHP domain protein K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 533.0
PYH1_k127_5467730_4 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 494.0
PYH1_k127_5467730_5 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 421.0
PYH1_k127_5467730_6 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 395.0
PYH1_k127_5467730_7 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 389.0
PYH1_k127_5467730_8 response regulator K20977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 311.0
PYH1_k127_5467730_9 PFAM YCII-related K09780 - - 0.000000000000000000000000000000000000000000000000001118 184.0
PYH1_k127_5487744_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000001715 214.0
PYH1_k127_5487744_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000001881 149.0
PYH1_k127_5487744_2 - - - - 0.00000000000000004674 86.0
PYH1_k127_5487744_3 Oxidoreductase family, NAD-binding Rossmann fold K13327 - 1.1.1.384 0.000000001897 60.0
PYH1_k127_549370_0 AmpG muropeptide MFS transporter K08218 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 601.0
PYH1_k127_549370_1 exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 523.0
PYH1_k127_549370_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 414.0
PYH1_k127_549370_3 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
PYH1_k127_549370_4 COG2202 FOG PAS PAC domain K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000007434 221.0
PYH1_k127_5513418_0 type I secretion outer membrane protein, TolC K12340 - - 6.763e-221 691.0
PYH1_k127_5513418_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000004683 245.0
PYH1_k127_5513418_2 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000007704 64.0
PYH1_k127_5676875_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.239e-309 949.0
PYH1_k127_5676875_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.984e-291 896.0
PYH1_k127_5676875_2 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 7.705e-222 691.0
PYH1_k127_5676875_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 584.0
PYH1_k127_5676875_4 acetyl-CoA carboxylase biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 578.0
PYH1_k127_5676875_5 MJ0042 family finger-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
PYH1_k127_5676875_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 331.0
PYH1_k127_5676875_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009693 243.0
PYH1_k127_5729496_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1262.0
PYH1_k127_5729496_1 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 1.2e-260 806.0
PYH1_k127_5729496_10 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000002957 169.0
PYH1_k127_5729496_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000000000000000000000495 149.0
PYH1_k127_5729496_12 Fe-S assembly protein IscX - - - 0.000000000000000000000003647 101.0
PYH1_k127_5729496_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 4.222e-211 659.0
PYH1_k127_5729496_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 1.723e-198 621.0
PYH1_k127_5729496_4 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 458.0
PYH1_k127_5729496_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 449.0
PYH1_k127_5729496_6 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 424.0
PYH1_k127_5729496_7 molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 284.0
PYH1_k127_5729496_8 PFAM FlgN family protein K02399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 281.0
PYH1_k127_5729496_9 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
PYH1_k127_5753983_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 1.483e-214 667.0
PYH1_k127_5753983_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 394.0
PYH1_k127_5753983_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 304.0
PYH1_k127_5753983_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 286.0
PYH1_k127_5753983_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 284.0
PYH1_k127_5753983_5 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000003792 264.0
PYH1_k127_5753983_6 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007958 255.0
PYH1_k127_5753983_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000008777 230.0
PYH1_k127_5763512_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 566.0
PYH1_k127_5763512_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000008208 213.0
PYH1_k127_5793628_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 9.473e-298 914.0
PYH1_k127_5793628_1 Polysulphide reductase, NrfD - - - 5.767e-225 700.0
PYH1_k127_5793628_2 formate dehydrogenase, beta subunit - - - 8.962e-204 635.0
PYH1_k127_5807485_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15576,K22067 - - 9.54e-257 794.0
PYH1_k127_5807485_1 response regulator K07183 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
PYH1_k127_5807485_2 Uncharacterized protein conserved in bacteria (DUF2058) K09912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009651 273.0
PYH1_k127_5807485_3 Water Stress and Hypersensitive response - - - 0.00000000000000000000000000000000000000000000000000009204 191.0
PYH1_k127_58531_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000001204 179.0
PYH1_k127_58531_1 - - - - 0.0000000000000000000000000000004856 138.0
PYH1_k127_5870722_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.821e-203 636.0
PYH1_k127_5870722_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 7.32e-200 624.0
PYH1_k127_5870722_2 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 604.0
PYH1_k127_5870722_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 445.0
PYH1_k127_5881067_0 FtsK SpoIIIE K03466 - - 0.0 1432.0
PYH1_k127_5881067_1 PFAM glycosyl transferase family 39 - - - 2.727e-284 876.0
PYH1_k127_5881067_10 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000000000000000000000000000000000000000000000000000000000000003627 250.0
PYH1_k127_5881067_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.423e-250 773.0
PYH1_k127_5881067_3 Pfam Glycosyl transferase family 2 - - - 1.375e-205 644.0
PYH1_k127_5881067_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 3.288e-204 636.0
PYH1_k127_5881067_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 550.0
PYH1_k127_5881067_6 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 474.0
PYH1_k127_5881067_7 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 438.0
PYH1_k127_5881067_8 DnaJ-class molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 344.0
PYH1_k127_5881067_9 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 319.0
PYH1_k127_5894439_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1010.0
PYH1_k127_5894439_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000662 205.0
PYH1_k127_5894439_2 - - - - 0.00004127 47.0
PYH1_k127_5914713_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 4.945e-319 984.0
PYH1_k127_5914713_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.759e-237 742.0
PYH1_k127_5914713_10 protein conserved in bacteria K09806 - - 0.00000000000000000000000000000000131 132.0
PYH1_k127_5914713_11 Ammonium transporter K03320 - - 0.00000001202 59.0
PYH1_k127_5914713_2 anti-sigma regulatory factor - - - 5.248e-225 698.0
PYH1_k127_5914713_3 PFAM Type II secretion system protein E K02670 - - 4.15e-222 693.0
PYH1_k127_5914713_4 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 552.0
PYH1_k127_5914713_5 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 328.0
PYH1_k127_5914713_6 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002689 268.0
PYH1_k127_5914713_7 - K17762 - - 0.000000000000000000000000000000000000000000000000000000000000000001315 227.0
PYH1_k127_5914713_8 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000000002164 221.0
PYH1_k127_5914713_9 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000008626 222.0
PYH1_k127_5928395_0 Arylsulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 409.0
PYH1_k127_5928395_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 327.0
PYH1_k127_5928395_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 318.0
PYH1_k127_5928395_3 - - - - 0.0000000000000000000000000000000000002654 145.0
PYH1_k127_5967854_0 DNA polymerase X family K02347 - - 9.041e-312 961.0
PYH1_k127_5967854_1 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.585e-248 769.0
PYH1_k127_5967854_10 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 437.0
PYH1_k127_5967854_11 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 411.0
PYH1_k127_5967854_12 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 346.0
PYH1_k127_5967854_13 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
PYH1_k127_5967854_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
PYH1_k127_5967854_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002773 188.0
PYH1_k127_5967854_16 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH1_k127_5967854_17 protein conserved in bacteria - - - 0.00000000000000000000000000000000000002777 145.0
PYH1_k127_5967854_18 - - - - 0.00000000000000000000000000000000001254 142.0
PYH1_k127_5967854_19 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000005275 54.0
PYH1_k127_5967854_2 RNA binding S1 domain protein K06959 - - 2.129e-218 679.0
PYH1_k127_5967854_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 6.624e-209 655.0
PYH1_k127_5967854_4 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 520.0
PYH1_k127_5967854_5 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 516.0
PYH1_k127_5967854_6 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 514.0
PYH1_k127_5967854_7 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 482.0
PYH1_k127_5967854_8 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
PYH1_k127_5967854_9 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 443.0
PYH1_k127_5971567_0 Diguanylate cyclase K13590 - 2.7.7.65 0.0 1063.0
PYH1_k127_5971567_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 548.0
PYH1_k127_5971567_2 PFAM flagellar basal body FlaE domain protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 432.0
PYH1_k127_5971567_3 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 370.0
PYH1_k127_5971567_4 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 323.0
PYH1_k127_5971567_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 281.0
PYH1_k127_5971567_6 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001282 248.0
PYH1_k127_5971567_7 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000000001824 188.0
PYH1_k127_5973903_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 395.0
PYH1_k127_5973903_1 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 349.0
PYH1_k127_5973903_2 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 298.0
PYH1_k127_6008115_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0 1591.0
PYH1_k127_6008115_1 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0 1193.0
PYH1_k127_6008115_2 Involved in the tonB-independent uptake of proteins K03641 - - 1.324e-261 809.0
PYH1_k127_6008115_3 Mota tolq exbb proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 428.0
PYH1_k127_6008115_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 417.0
PYH1_k127_6008115_5 Cell division and transport-associated protein TolA K03646 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 368.0
PYH1_k127_6008115_6 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 319.0
PYH1_k127_6008115_7 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008881 239.0
PYH1_k127_6008115_8 tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.00000000000000000007657 88.0
PYH1_k127_6008115_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.000000000000001629 86.0
PYH1_k127_6023187_0 Acetolactate synthase K01652 - 2.2.1.6 0.0 1133.0
PYH1_k127_6023187_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.894e-319 978.0
PYH1_k127_6023187_10 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006607 237.0
PYH1_k127_6023187_11 Protein of unknown function (DUF3619) - - - 0.000000000000000000000000000000000000000000000000000000000003955 209.0
PYH1_k127_6023187_12 - - - - 0.00000000000000000000000000000000000000000000000000000000001797 207.0
PYH1_k127_6023187_13 membrane - - - 0.000000000000000000000000000000000000000000000000000000225 196.0
PYH1_k127_6023187_14 Permease, YjgP YjgQ family K07091 - - 0.00000000000000000000000000002424 117.0
PYH1_k127_6023187_15 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000004887 117.0
PYH1_k127_6023187_16 - - - - 0.00000000000000000000000001583 111.0
PYH1_k127_6023187_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.048e-218 679.0
PYH1_k127_6023187_3 Permease, YjgP YjgQ family K11720 - - 2.846e-215 674.0
PYH1_k127_6023187_4 UPF0761 membrane protein K07058 - - 1.949e-208 653.0
PYH1_k127_6023187_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 503.0
PYH1_k127_6023187_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 462.0
PYH1_k127_6023187_7 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 440.0
PYH1_k127_6023187_8 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 382.0
PYH1_k127_6023187_9 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 292.0
PYH1_k127_6057123_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 328.0
PYH1_k127_6057123_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002377 260.0
PYH1_k127_6061059_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002295 293.0
PYH1_k127_6061059_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000006927 160.0
PYH1_k127_606418_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0 999.0
PYH1_k127_606418_1 ubiquinone biosynthetic process from chorismate K03690 GO:0006082,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0019752,GO:0032150,GO:0042180,GO:0042181,GO:0043436,GO:0043648,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046417,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 302.0
PYH1_k127_6073464_0 Abc transporter K06158 - - 0.0 1145.0
PYH1_k127_6073464_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 2.4e-322 990.0
PYH1_k127_6073464_10 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000001339 209.0
PYH1_k127_6073464_11 DinB superfamily - - - 0.00000000000000000000000000164 118.0
PYH1_k127_6073464_2 PFAM aminotransferase class I and II K00842,K14155 - 4.4.1.8 6.413e-236 738.0
PYH1_k127_6073464_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 552.0
PYH1_k127_6073464_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 534.0
PYH1_k127_6073464_5 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 428.0
PYH1_k127_6073464_6 had-superfamily hydrolase subfamily ia, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 424.0
PYH1_k127_6073464_7 transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 338.0
PYH1_k127_6073464_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 358.0
PYH1_k127_6073464_9 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 287.0
PYH1_k127_6098586_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 6.76e-272 839.0
PYH1_k127_6098586_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 449.0
PYH1_k127_6098586_2 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004018 260.0
PYH1_k127_6098586_3 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000001052 162.0
PYH1_k127_6103784_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 439.0
PYH1_k127_6103784_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 422.0
PYH1_k127_6103784_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009012 273.0
PYH1_k127_6108387_0 Aminotransferase K01845 - 5.4.3.8 7.132e-268 827.0
PYH1_k127_6108387_1 Putative metallopeptidase domain - - - 1.153e-228 710.0
PYH1_k127_6108387_2 associated with various cellular activities - - - 4.187e-227 704.0
PYH1_k127_6108387_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 525.0
PYH1_k127_6108387_4 C4-dicarboxylate transporter malic acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 518.0
PYH1_k127_6108387_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 361.0
PYH1_k127_6108387_6 PFAM CheW domain protein K02659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 340.0
PYH1_k127_6108387_7 chemotaxis K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 327.0
PYH1_k127_6108387_8 RESPONSE REGULATOR receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003447 257.0
PYH1_k127_6108387_9 RESPONSE REGULATOR receiver K02658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007438 241.0
PYH1_k127_6124946_0 Protein conserved in bacteria - - - 0.0 1145.0
PYH1_k127_6124946_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 580.0
PYH1_k127_6124946_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 454.0
PYH1_k127_6124946_3 3-5 exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002853 257.0
PYH1_k127_6124946_4 Protein of unknown function (DUF1318) K09978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 249.0
PYH1_k127_6124946_5 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000003298 217.0
PYH1_k127_6124946_6 Competence protein ComEA K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000001919 160.0
PYH1_k127_6124946_7 - - - - 0.000000000000000000000005328 106.0
PYH1_k127_615086_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.4e-322 989.0
PYH1_k127_6158849_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 536.0
PYH1_k127_6158849_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
PYH1_k127_6158849_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 286.0
PYH1_k127_6171502_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 7.491e-233 724.0
PYH1_k127_6171502_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 391.0
PYH1_k127_6171502_2 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 307.0
PYH1_k127_6171502_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000003891 201.0
PYH1_k127_6171502_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000003573 118.0
PYH1_k127_6194032_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.891e-287 884.0
PYH1_k127_6194032_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 336.0
PYH1_k127_6216259_0 Ribosomal RNA adenine dimethylase - - - 0.0 1376.0
PYH1_k127_6216259_1 ligase activity - - - 1.733e-226 705.0
PYH1_k127_6216259_10 flagellar protein FlaG K06603 - - 0.0000000000000000000000001287 110.0
PYH1_k127_6216259_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000007112 97.0
PYH1_k127_6216259_13 Transcriptional regulator - - - 0.00000003899 57.0
PYH1_k127_6216259_2 Pyridoxal-dependent decarboxylase K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 581.0
PYH1_k127_6216259_3 Flagellar hook-length control protein FliK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 545.0
PYH1_k127_6216259_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 479.0
PYH1_k127_6216259_5 Protein of unknown function (DUF2802) - - - 0.00000000000000000000000000000000000000000000000000000000001264 209.0
PYH1_k127_6216259_6 Flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000006482 150.0
PYH1_k127_6216259_7 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.00000000000000000000000000000002042 128.0
PYH1_k127_6216259_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000007476 129.0
PYH1_k127_6229523_0 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.602e-271 845.0
PYH1_k127_6229523_1 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 7.029e-252 780.0
PYH1_k127_6229523_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 3.425e-207 652.0
PYH1_k127_6229523_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 8.925e-199 620.0
PYH1_k127_6229523_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 585.0
PYH1_k127_6229523_5 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 384.0
PYH1_k127_6229523_6 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 317.0
PYH1_k127_6229523_7 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0000000000000000413 82.0
PYH1_k127_6249231_0 Molecular chaperone. Has ATPase activity K04079 - - 1.254e-268 828.0
PYH1_k127_6249231_1 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 352.0
PYH1_k127_6306497_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 549.0
PYH1_k127_6306497_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 521.0
PYH1_k127_6306497_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000001837 154.0
PYH1_k127_6306497_3 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000002829 130.0
PYH1_k127_6306497_4 membrane - - - 0.00000000000000000000000000000001741 126.0
PYH1_k127_6336443_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.064e-315 969.0
PYH1_k127_6336443_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 384.0
PYH1_k127_6336443_2 Anti sigma-E protein RseA K03597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007972 254.0
PYH1_k127_6336443_3 negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000000000000000000000000000000000003335 217.0
PYH1_k127_6370270_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.613e-216 674.0
PYH1_k127_6370270_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 597.0
PYH1_k127_6370270_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 298.0
PYH1_k127_6370270_3 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 294.0
PYH1_k127_6370270_4 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 287.0
PYH1_k127_6370270_5 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003023 267.0
PYH1_k127_6370270_6 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001134 246.0
PYH1_k127_6370270_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000000000000007351 169.0
PYH1_k127_6370270_8 Sulfurtransferase - - - 0.000000000000000000000000000000000000201 141.0
PYH1_k127_6370270_9 type II secretion system protein E K02454,K02652,K12276 - - 0.000000000000000006889 83.0
PYH1_k127_6407430_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 595.0
PYH1_k127_6407430_1 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 571.0
PYH1_k127_6407430_2 membrane protein, terc K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 554.0
PYH1_k127_6407430_3 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 554.0
PYH1_k127_6407430_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 529.0
PYH1_k127_6407430_5 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 317.0
PYH1_k127_6407430_6 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000002288 211.0
PYH1_k127_6407430_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000001263 129.0
PYH1_k127_6407430_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000004776 130.0
PYH1_k127_6430509_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.43e-286 884.0
PYH1_k127_6430509_1 Metallo-beta-lactamase superfamily - - - 5.582e-211 659.0
PYH1_k127_6430509_2 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 426.0
PYH1_k127_6430509_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
PYH1_k127_6430509_4 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 303.0
PYH1_k127_6430509_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 294.0
PYH1_k127_6430509_6 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000007775 213.0
PYH1_k127_6430509_7 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000009056 200.0
PYH1_k127_6433924_0 Diguanylate cyclase - - - 0.0 1368.0
PYH1_k127_6433924_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 3.31e-208 651.0
PYH1_k127_6433924_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 481.0
PYH1_k127_6433924_3 Short-chain dehydrogenase reductase (SDR) K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 456.0
PYH1_k127_6433924_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
PYH1_k127_6436681_0 Belongs to the heme-copper respiratory oxidase family - - - 1.873e-228 713.0
PYH1_k127_6436681_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 583.0
PYH1_k127_6436681_2 Nitric oxide reductase K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 455.0
PYH1_k127_6436681_3 cytochrome C K02305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 295.0
PYH1_k127_6436681_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004568 269.0
PYH1_k127_6436681_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004948 264.0
PYH1_k127_6436681_6 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000000372 179.0
PYH1_k127_6438916_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1304.0
PYH1_k127_6438916_1 4Fe-4S dicluster domain - - - 0.0 1016.0
PYH1_k127_6438916_10 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000000000000000000000000000000000000001347 213.0
PYH1_k127_6438916_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000001775 192.0
PYH1_k127_6438916_12 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000168 146.0
PYH1_k127_6438916_13 Protein of unknown function (DUF504) - - - 0.0000000000000000000000000000004073 123.0
PYH1_k127_6438916_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 1.217e-263 818.0
PYH1_k127_6438916_3 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 599.0
PYH1_k127_6438916_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 511.0
PYH1_k127_6438916_5 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 481.0
PYH1_k127_6438916_6 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 472.0
PYH1_k127_6438916_7 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 350.0
PYH1_k127_6438916_8 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 339.0
PYH1_k127_6438916_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 323.0
PYH1_k127_6441307_0 Seven times multi-haem cytochrome CxxCH - - - 1.115e-211 669.0
PYH1_k127_6441307_1 Cell division inhibitor - - - 0.00000000000000001892 83.0
PYH1_k127_6454491_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.196e-282 867.0
PYH1_k127_6454491_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 3.24e-256 790.0
PYH1_k127_6454491_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.755e-248 767.0
PYH1_k127_6454491_3 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 563.0
PYH1_k127_6454491_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 397.0
PYH1_k127_6454491_5 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000006444 231.0
PYH1_k127_6454491_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000000000006623 190.0
PYH1_k127_6454491_7 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000000000000000000000000000000006253 152.0
PYH1_k127_6464089_0 Molybdopterin oxidoreductase Fe4S4 domain K00372 - - 0.0 1107.0
PYH1_k127_6464089_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K05297 - 1.18.1.1,1.7.1.15 0.00000001368 58.0
PYH1_k127_6467571_0 transglycosylase K08307 - - 2.311e-270 836.0
PYH1_k127_6467571_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 533.0
PYH1_k127_6481039_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 2.014e-219 683.0
PYH1_k127_6481039_1 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 293.0
PYH1_k127_6481039_3 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000003662 195.0
PYH1_k127_6493183_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 6.517e-290 893.0
PYH1_k127_6493183_1 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 484.0
PYH1_k127_6493183_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000000000000000000008484 235.0
PYH1_k127_6493183_3 Uncharacterized ACR, COG1993 - - - 0.00000000000000000000000000000000000000000000003449 171.0
PYH1_k127_6493183_4 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000000003345 164.0
PYH1_k127_6509276_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1208.0
PYH1_k127_6509276_1 IS30 family K07482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 379.0
PYH1_k127_6509276_2 Protein of unknown function (DUF560) - - - 0.00000008388 60.0
PYH1_k127_6509276_3 - - - - 0.000002675 49.0
PYH1_k127_6519931_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 607.0
PYH1_k127_6519931_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 542.0
PYH1_k127_6519931_2 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000004699 164.0
PYH1_k127_6519931_3 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000000000000000000003352 150.0
PYH1_k127_6572918_0 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 426.0
PYH1_k127_6572918_1 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 302.0
PYH1_k127_6572918_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 292.0
PYH1_k127_6572918_3 - - - - 0.000000000000000000000000000000000000000000000005685 175.0
PYH1_k127_6741410_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 4.548e-216 673.0
PYH1_k127_6741410_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 2.206e-210 656.0
PYH1_k127_6741410_2 Transcriptional regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 436.0
PYH1_k127_6741410_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 413.0
PYH1_k127_6741410_4 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001247 246.0
PYH1_k127_6741410_5 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000407 159.0
PYH1_k127_6741410_6 abc transporter K02003 - - 0.0000000000000000000000000000000001971 135.0
PYH1_k127_6750340_0 - - - - 0.00000000000000000000000000000000004756 150.0
PYH1_k127_6750340_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000001311 62.0
PYH1_k127_6777284_0 Periplasmic copper-binding K07218 - - 3.005e-203 640.0
PYH1_k127_6777284_1 4Fe-4S binding domain K02574 - - 1.501e-198 621.0
PYH1_k127_6777284_10 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000372 179.0
PYH1_k127_6777284_2 4Fe-4S dicluster domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 554.0
PYH1_k127_6777284_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 544.0
PYH1_k127_6777284_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 539.0
PYH1_k127_6777284_5 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 524.0
PYH1_k127_6777284_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 463.0
PYH1_k127_6777284_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 416.0
PYH1_k127_6777284_8 NosL - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002226 274.0
PYH1_k127_6777284_9 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000003142 240.0
PYH1_k127_6851270_0 response regulator K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.093e-287 884.0
PYH1_k127_6851270_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 2.093e-267 824.0
PYH1_k127_6851270_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 485.0
PYH1_k127_6851270_3 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 348.0
PYH1_k127_6851270_4 Pfam Glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 295.0
PYH1_k127_6851270_5 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 272.0
PYH1_k127_6851270_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003847 256.0
PYH1_k127_6851270_7 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002217 254.0
PYH1_k127_6851270_8 Thioredoxin domain - - - 0.00000000000000000000000000000000028 132.0
PYH1_k127_6851270_9 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000001371 76.0
PYH1_k127_6864585_0 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 573.0
PYH1_k127_6864585_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 493.0
PYH1_k127_6864585_2 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 458.0
PYH1_k127_6864585_3 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 374.0
PYH1_k127_6864585_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 330.0
PYH1_k127_6864585_5 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001164 276.0
PYH1_k127_6867784_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0 1095.0
PYH1_k127_6867784_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 5.705e-311 955.0
PYH1_k127_6867784_10 Short C-terminal domain K08982 - - 0.0000000000001542 73.0
PYH1_k127_6867784_11 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000002764 62.0
PYH1_k127_6867784_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 9.328e-239 739.0
PYH1_k127_6867784_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 8.419e-235 733.0
PYH1_k127_6867784_4 Putative diguanylate phosphodiesterase - - - 1.59e-224 726.0
PYH1_k127_6867784_5 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 482.0
PYH1_k127_6867784_6 17 kDa surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 293.0
PYH1_k127_6867784_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000000001591 164.0
PYH1_k127_6867784_8 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000003049 156.0
PYH1_k127_6867784_9 - - - - 0.00000000000000000001014 93.0
PYH1_k127_6869673_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 571.0
PYH1_k127_6869673_1 ADP-glyceromanno-heptose 6-epimerase activity K00091,K01710 - 1.1.1.219,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 353.0
PYH1_k127_6869673_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000001401 203.0
PYH1_k127_6889135_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1675.0
PYH1_k127_6889135_1 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.776e-315 968.0
PYH1_k127_6889135_2 PFAM EAL domain protein - - - 2.84e-225 702.0
PYH1_k127_6889135_3 - - - - 0.0000000000000000000000000000000000000000000000000000000003239 203.0
PYH1_k127_6889135_4 Modulates RecA activity K03565 - - 0.0000000000000000000000002735 104.0
PYH1_k127_6906333_0 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002147 243.0
PYH1_k127_6906333_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000003598 220.0
PYH1_k127_6906333_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000003898 154.0
PYH1_k127_6920509_0 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 426.0
PYH1_k127_6920509_1 Aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 376.0
PYH1_k127_6920509_2 Tetratricopeptide repeat K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 361.0
PYH1_k127_6920509_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000004769 225.0
PYH1_k127_6924057_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.502e-268 831.0
PYH1_k127_6924057_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 599.0
PYH1_k127_6924057_2 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 460.0
PYH1_k127_6924057_3 protein conserved in bacteria K11719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 372.0
PYH1_k127_6924057_4 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 335.0
PYH1_k127_6924057_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000000003966 199.0
PYH1_k127_6924057_6 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000007818 181.0
PYH1_k127_6924057_7 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000002636 120.0
PYH1_k127_6962240_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 4.381e-317 972.0
PYH1_k127_6962240_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 427.0
PYH1_k127_6962240_2 Cation efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 371.0
PYH1_k127_6962240_3 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 329.0
PYH1_k127_6962240_4 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009835 270.0
PYH1_k127_6962240_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 255.0
PYH1_k127_6962240_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000216 213.0
PYH1_k127_6962240_7 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000001304 189.0
PYH1_k127_6962240_8 - - - - 0.000000000000000000000000000000000000000000000006784 172.0
PYH1_k127_6962240_9 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000004973 160.0
PYH1_k127_696410_0 ribonuclease II K01147 - 3.1.13.1 0.0 1185.0
PYH1_k127_696410_1 Diguanylate cyclase - - - 0.0 1160.0
PYH1_k127_696410_10 esterase K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 346.0
PYH1_k127_696410_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 321.0
PYH1_k127_696410_12 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
PYH1_k127_696410_13 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004206 265.0
PYH1_k127_696410_14 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
PYH1_k127_696410_15 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000001502 221.0
PYH1_k127_696410_16 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000002413 165.0
PYH1_k127_696410_17 sulfur carrier activity K04085,K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000000002801 104.0
PYH1_k127_696410_2 Diguanylate cyclase (GGDEF) domain - - - 0.0 1035.0
PYH1_k127_696410_3 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 6.922e-284 874.0
PYH1_k127_696410_4 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 568.0
PYH1_k127_696410_5 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 519.0
PYH1_k127_696410_6 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 519.0
PYH1_k127_696410_7 sulfur carrier activity K04085,K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 467.0
PYH1_k127_696410_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 367.0
PYH1_k127_696410_9 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
PYH1_k127_6974729_0 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 482.0
PYH1_k127_6974729_1 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 388.0
PYH1_k127_6974729_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
PYH1_k127_6974729_3 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000114 67.0
PYH1_k127_6977022_0 Putative transposase - - - 1.809e-195 614.0
PYH1_k127_6977022_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 407.0
PYH1_k127_6977022_3 HTH-type transcriptional regulator (heavy metal copper efflux protein) - - - 0.0000000000003546 73.0
PYH1_k127_6977022_4 - - - - 0.0000000003779 60.0
PYH1_k127_6977022_5 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000001313 57.0
PYH1_k127_6990480_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 4.837e-273 841.0
PYH1_k127_6990480_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 2.931e-257 801.0
PYH1_k127_6990480_2 Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 556.0
PYH1_k127_6990480_3 - - - - 0.00000000000000000000000000000000000000003801 153.0
PYH1_k127_6998712_0 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 0.0 1586.0
PYH1_k127_6998712_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.046e-285 876.0
PYH1_k127_6998712_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.187e-285 876.0
PYH1_k127_6998712_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 482.0
PYH1_k127_6998712_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 332.0
PYH1_k127_6998712_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 299.0
PYH1_k127_6998712_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005876 279.0
PYH1_k127_6998712_7 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
PYH1_k127_6998712_8 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000000000000000000000000004722 206.0
PYH1_k127_7018316_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1944.0
PYH1_k127_7018316_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 1.993e-216 676.0
PYH1_k127_7018316_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.925e-196 617.0
PYH1_k127_7018316_3 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 422.0
PYH1_k127_7018316_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 301.0
PYH1_k127_7018316_6 GAF domain protein - - - 0.000601 43.0
PYH1_k127_7021901_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1272.0
PYH1_k127_7021901_1 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 598.0
PYH1_k127_7021901_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 290.0
PYH1_k127_7029377_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 518.0
PYH1_k127_7029377_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 488.0
PYH1_k127_7029377_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 355.0
PYH1_k127_7029377_3 PFAM cytochrome c - - - 0.0000000000000002887 88.0
PYH1_k127_7036141_0 Membrane protein FdrA - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 419.0
PYH1_k127_7036141_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 319.0
PYH1_k127_7036141_2 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
PYH1_k127_7036141_3 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000007861 149.0
PYH1_k127_7036141_4 - - - - 0.0000000002419 62.0
PYH1_k127_704154_0 flagellar hook-associated protein K02396 - - 2.129e-229 728.0
PYH1_k127_704154_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 1.812e-206 646.0
PYH1_k127_704154_2 flagellar basal-body rod protein K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 476.0
PYH1_k127_704154_3 Flagellar rod assembly protein muramidase FlgJ K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 463.0
PYH1_k127_704154_4 Belongs to the flagella basal body rod proteins family K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 448.0
PYH1_k127_704154_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 440.0
PYH1_k127_704154_6 Bacterial flagellin N-terminal helical region K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 404.0
PYH1_k127_704154_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000003174 174.0
PYH1_k127_704154_8 Flagellar basal body rod FlgEFG protein C-terminal K02390 - - 0.000000000003702 66.0
PYH1_k127_7065116_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 396.0
PYH1_k127_7065116_1 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 379.0
PYH1_k127_7065116_2 Involved in initiation control of chromosome replication - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
PYH1_k127_7065116_3 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000004401 145.0
PYH1_k127_7065116_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000003426 118.0
PYH1_k127_7065116_5 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.000002566 51.0
PYH1_k127_7089977_0 Histidine kinase - - - 0.0 1390.0
PYH1_k127_7089977_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0 1056.0
PYH1_k127_7089977_10 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001811 272.0
PYH1_k127_7089977_11 PFAM AMMECR1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004171 253.0
PYH1_k127_7089977_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
PYH1_k127_7089977_13 - - - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
PYH1_k127_7089977_14 PFAM NLP P60 protein - - - 0.00000000000000000000000000000000000000000000004778 174.0
PYH1_k127_7089977_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000000009743 164.0
PYH1_k127_7089977_16 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000003694 74.0
PYH1_k127_7089977_17 - - - - 0.0000000002142 63.0
PYH1_k127_7089977_18 - - - - 0.000002525 49.0
PYH1_k127_7089977_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.153e-306 941.0
PYH1_k127_7089977_3 Radical SAM K04069 - 1.97.1.4 1.947e-238 741.0
PYH1_k127_7089977_4 Diguanylate cyclase - - - 1.257e-224 717.0
PYH1_k127_7089977_5 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 529.0
PYH1_k127_7089977_6 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 500.0
PYH1_k127_7089977_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 441.0
PYH1_k127_7089977_8 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 391.0
PYH1_k127_7089977_9 Histidine kinase K03413,K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 346.0
PYH1_k127_7095142_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.772e-221 686.0
PYH1_k127_7095142_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 1.374e-212 663.0
PYH1_k127_7095142_2 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 357.0
PYH1_k127_7095142_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 302.0
PYH1_k127_7095142_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002234 269.0
PYH1_k127_7097224_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 415.0
PYH1_k127_7097224_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 400.0
PYH1_k127_7097224_2 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 340.0
PYH1_k127_7106757_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1354.0
PYH1_k127_7106757_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 286.0
PYH1_k127_7106757_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 278.0
PYH1_k127_7106757_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
PYH1_k127_7106757_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000006708 215.0
PYH1_k127_7106757_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000000000005239 169.0
PYH1_k127_7124167_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1793.0
PYH1_k127_7124167_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 499.0
PYH1_k127_7124167_2 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 472.0
PYH1_k127_7124167_3 PFAM pentapeptide repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 416.0
PYH1_k127_7124167_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 372.0
PYH1_k127_7128427_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 594.0
PYH1_k127_7128427_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 310.0
PYH1_k127_7128427_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001216 209.0
PYH1_k127_7128427_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000008503 202.0
PYH1_k127_7128427_4 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000005277 175.0
PYH1_k127_7145141_0 HI0933 family K07007 - - 4.851e-255 787.0
PYH1_k127_7145141_1 Periplasmic copper-binding K07218 - - 2.189e-232 722.0
PYH1_k127_7145141_2 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 2.81e-218 679.0
PYH1_k127_7145141_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 548.0
PYH1_k127_7145141_4 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 522.0
PYH1_k127_7145141_5 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 341.0
PYH1_k127_7145141_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000001198 185.0
PYH1_k127_7189235_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 5.911e-267 822.0
PYH1_k127_7189235_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 594.0
PYH1_k127_7189235_2 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 588.0
PYH1_k127_7189235_3 Anthranilate synthase K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 499.0
PYH1_k127_7189235_4 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 490.0
PYH1_k127_7189235_5 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 481.0
PYH1_k127_7189235_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000887 278.0
PYH1_k127_7189235_7 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000004289 183.0
PYH1_k127_7189235_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000001021 147.0
PYH1_k127_7189235_9 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000002588 81.0
PYH1_k127_7204805_0 Putative diguanylate phosphodiesterase - - - 0.0 1274.0
PYH1_k127_7204805_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.848e-295 906.0
PYH1_k127_7204805_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 2.149e-245 761.0
PYH1_k127_7204805_3 transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 556.0
PYH1_k127_7204805_4 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 551.0
PYH1_k127_7204805_5 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000000000000004568 210.0
PYH1_k127_7204805_6 Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000000000000009801 169.0
PYH1_k127_7204805_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000003764 150.0
PYH1_k127_7209073_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 3.727e-266 822.0
PYH1_k127_7212227_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 582.0
PYH1_k127_7212227_1 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 585.0
PYH1_k127_7212227_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 558.0
PYH1_k127_7212227_3 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 415.0
PYH1_k127_7212227_4 CRP FNR family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 408.0
PYH1_k127_7212227_5 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 366.0
PYH1_k127_7212227_6 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 340.0
PYH1_k127_7212227_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 319.0
PYH1_k127_7239970_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.479e-312 957.0
PYH1_k127_7239970_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 1.183e-237 736.0
PYH1_k127_7239970_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 538.0
PYH1_k127_7239970_3 TRANSCRIPTIONal REGULATOR, GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 481.0
PYH1_k127_7239970_4 malate dehydrogenase (decarboxylating) (NAD+) activity K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000068 53.0
PYH1_k127_7253488_0 TonB dependent receptor K02014 - - 0.0 1070.0
PYH1_k127_7253488_1 Outer membrane protein beta-barrel family - - - 4.433e-255 805.0
PYH1_k127_7253488_10 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 370.0
PYH1_k127_7253488_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 351.0
PYH1_k127_7253488_12 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002746 280.0
PYH1_k127_7253488_13 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000029 267.0
PYH1_k127_7253488_14 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001915 263.0
PYH1_k127_7253488_15 Pfam Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 250.0
PYH1_k127_7253488_16 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000002896 93.0
PYH1_k127_7253488_2 membrane-bound lytic murein transglycosylase K08304 - - 7.133e-209 650.0
PYH1_k127_7253488_3 4 iron, 4 sulfur cluster binding K00226,K02574 - 1.3.98.1 1.915e-205 641.0
PYH1_k127_7253488_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 601.0
PYH1_k127_7253488_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 568.0
PYH1_k127_7253488_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 464.0
PYH1_k127_7253488_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 449.0
PYH1_k127_7253488_8 Mota tolq exbb proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 400.0
PYH1_k127_7253488_9 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 376.0
PYH1_k127_7254764_0 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1108.0
PYH1_k127_7254764_1 - - - - 4.14e-261 813.0
PYH1_k127_7254764_2 Type II secretion system K02653 - - 3.692e-237 736.0
PYH1_k127_7254764_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 345.0
PYH1_k127_7254764_4 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000509 186.0
PYH1_k127_7257772_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.0 1185.0
PYH1_k127_7257772_1 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 6.625e-253 784.0
PYH1_k127_7286388_0 Histidine kinase K02487,K06596 - - 0.0 1699.0
PYH1_k127_7286388_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000008944 89.0
PYH1_k127_7369047_0 Belongs to the peptidase M17 family K01255 - 3.4.11.1 7.833e-292 898.0
PYH1_k127_7369047_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000005298 181.0
PYH1_k127_7369047_2 - - - - 0.0000000000000001401 87.0
PYH1_k127_7369852_0 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 472.0
PYH1_k127_7369852_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 452.0
PYH1_k127_7369852_2 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000004624 134.0
PYH1_k127_7543246_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0 1058.0
PYH1_k127_7543246_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.859e-278 859.0
PYH1_k127_7543246_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 580.0
PYH1_k127_7543246_3 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 296.0
PYH1_k127_7543246_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000001138 248.0
PYH1_k127_7543246_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000000000000000000000000009553 163.0
PYH1_k127_7565015_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1597.0
PYH1_k127_7565015_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.357e-311 956.0
PYH1_k127_7565015_2 Permease, YjgP YjgQ family K07091 - - 1.658e-198 621.0
PYH1_k127_7565015_3 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 286.0
PYH1_k127_7573705_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0 1342.0
PYH1_k127_7573705_1 von Willebrand factor (vWF) type A domain K02448 - - 0.0 1287.0
PYH1_k127_7573705_10 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004513 269.0
PYH1_k127_7573705_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000006193 228.0
PYH1_k127_7573705_12 - - - - 0.000000000001658 66.0
PYH1_k127_7573705_2 PUA-like domain K00958 - 2.7.7.4 7.042e-270 830.0
PYH1_k127_7573705_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 580.0
PYH1_k127_7573705_4 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 523.0
PYH1_k127_7573705_5 beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 448.0
PYH1_k127_7573705_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 428.0
PYH1_k127_7573705_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 409.0
PYH1_k127_7573705_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 353.0
PYH1_k127_7573705_9 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 299.0
PYH1_k127_7577289_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1658.0
PYH1_k127_7577289_1 Helicase K03657 - 3.6.4.12 0.0 1373.0
PYH1_k127_7577289_10 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000000000000000000000000000000006824 160.0
PYH1_k127_7577289_11 Mo-molybdopterin cofactor metabolic process K03636,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 0.00000000000000000000000000000000000000002195 153.0
PYH1_k127_7577289_12 acetyl-CoA hydrolase K18288 - - 0.0000000005149 61.0
PYH1_k127_7577289_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 5.827e-197 615.0
PYH1_k127_7577289_3 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 605.0
PYH1_k127_7577289_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 574.0
PYH1_k127_7577289_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 453.0
PYH1_k127_7577289_6 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 451.0
PYH1_k127_7577289_7 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 354.0
PYH1_k127_7577289_8 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 345.0
PYH1_k127_7577289_9 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004825 229.0
PYH1_k127_7580623_0 peptidase - - - 2.12e-262 812.0
PYH1_k127_7580623_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.562e-248 767.0
PYH1_k127_7580623_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000001547 231.0
PYH1_k127_7603803_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1350.0
PYH1_k127_7603803_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1140.0
PYH1_k127_7603803_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.779e-310 957.0
PYH1_k127_7603803_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 5.658e-227 704.0
PYH1_k127_7603803_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 477.0
PYH1_k127_7603803_5 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 401.0
PYH1_k127_7603803_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 390.0
PYH1_k127_7603803_7 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 378.0
PYH1_k127_7603803_8 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 317.0
PYH1_k127_7603803_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 286.0
PYH1_k127_7605803_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.462e-250 775.0
PYH1_k127_7605803_1 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 552.0
PYH1_k127_7605803_2 Sporulation related domain K03749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 324.0
PYH1_k127_7605803_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 314.0
PYH1_k127_7605803_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000267 278.0
PYH1_k127_7605803_5 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 259.0
PYH1_k127_7605803_6 - - - - 0.0000000000000000000000000000000000000000000000000000003227 194.0
PYH1_k127_76210_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1146.0
PYH1_k127_76210_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1139.0
PYH1_k127_76210_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.77e-264 815.0
PYH1_k127_76210_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 481.0
PYH1_k127_76210_4 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K00240,K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 0.0000000000000000000003721 102.0
PYH1_k127_76210_5 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.0000000000000000001107 88.0
PYH1_k127_7626923_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0 1133.0
PYH1_k127_7626923_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 9.33e-218 679.0
PYH1_k127_7626923_2 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 494.0
PYH1_k127_7626923_3 Pfam ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 424.0
PYH1_k127_7626923_4 sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000213 273.0
PYH1_k127_7626923_5 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000002501 221.0
PYH1_k127_7626923_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000006221 200.0
PYH1_k127_7626923_7 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000000000000000001979 195.0
PYH1_k127_7626923_8 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000001841 176.0
PYH1_k127_7626923_9 Putative motility protein - - - 0.0003365 45.0
PYH1_k127_7628304_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0 1079.0
PYH1_k127_7628304_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 2.352e-244 758.0
PYH1_k127_7628304_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 357.0
PYH1_k127_7628304_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001594 274.0
PYH1_k127_7628304_4 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000006122 201.0
PYH1_k127_7628304_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000009963 156.0
PYH1_k127_7631679_0 FAD linked oxidase domain protein - - - 0.0 1818.0
PYH1_k127_7631679_1 - - - - 3.957e-302 931.0
PYH1_k127_7631679_2 Histidine kinase K07636 - 2.7.13.3 5.18e-262 810.0
PYH1_k127_7631679_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 488.0
PYH1_k127_7631679_4 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 468.0
PYH1_k127_7631679_5 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 451.0
PYH1_k127_7631679_6 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004597 273.0
PYH1_k127_7633353_0 Cytochrome d1, heme K15864 - 1.7.2.1,1.7.99.1 8.265e-300 921.0
PYH1_k127_7633353_1 Radical SAM - - - 2.491e-255 788.0
PYH1_k127_7633353_10 blue (type 1) copper - - - 0.00000000000000000000000000000000000000000003344 162.0
PYH1_k127_7633353_11 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000000000000000000916 150.0
PYH1_k127_7633353_2 cytochrome d1, heme region K19345 - - 9.052e-250 771.0
PYH1_k127_7633353_3 COG1522 Transcriptional regulators - - - 3.841e-206 644.0
PYH1_k127_7633353_4 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 528.0
PYH1_k127_7633353_5 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 443.0
PYH1_k127_7633353_6 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 394.0
PYH1_k127_7633353_7 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 357.0
PYH1_k127_7633353_8 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 305.0
PYH1_k127_7633353_9 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003849 273.0
PYH1_k127_7641953_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 9.802e-255 788.0
PYH1_k127_7641953_1 DNA polymerase III delta subunit K02340 - 2.7.7.7 1.748e-201 629.0
PYH1_k127_7641953_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 395.0
PYH1_k127_7641953_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 362.0
PYH1_k127_7641953_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 308.0
PYH1_k127_7641953_5 - - - - 0.0000000000000000000000000000000000000000000000000001418 186.0
PYH1_k127_7641953_6 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000002287 152.0
PYH1_k127_7641953_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000001058 156.0
PYH1_k127_7644246_0 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000006986 149.0
PYH1_k127_7644246_1 - - - - 0.00000000000000000000007825 106.0
PYH1_k127_7644246_2 - - - - 0.0000005972 53.0
PYH1_k127_7644246_3 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00001401 47.0
PYH1_k127_7645853_0 RimK-like ATPgrasp N-terminal domain - - - 3.332e-249 779.0
PYH1_k127_7645853_1 PFAM VanZ family protein - - - 3.84e-234 728.0
PYH1_k127_7645853_2 Glutamate-cysteine ligase family 2(GCS2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 599.0
PYH1_k127_7645853_3 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 449.0
PYH1_k127_7645853_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 424.0
PYH1_k127_7645853_5 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 336.0
PYH1_k127_7645853_6 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 293.0
PYH1_k127_7645853_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000004406 216.0
PYH1_k127_7645853_8 MazG-like family - - - 0.0000000000000000000000000000015 126.0
PYH1_k127_7685593_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0 1019.0
PYH1_k127_7685593_1 'signal transduction protein - - - 4.967e-265 821.0
PYH1_k127_7685593_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 4.969e-231 717.0
PYH1_k127_7685593_3 PFAM Outer membrane efflux protein - - - 2.584e-224 702.0
PYH1_k127_7685593_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 546.0
PYH1_k127_7685593_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 521.0
PYH1_k127_7685593_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 475.0
PYH1_k127_7685593_7 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000000009191 213.0
PYH1_k127_7685593_8 Copper binding periplasmic protein CusF - - - 0.000000000000000000000000000000000000003132 147.0
PYH1_k127_7685593_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000002187 139.0
PYH1_k127_7690818_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1054.0
PYH1_k127_7690818_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 3.706e-294 905.0
PYH1_k127_7690818_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.341e-289 893.0
PYH1_k127_7690818_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 3.949e-196 612.0
PYH1_k127_7690818_4 heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 598.0
PYH1_k127_7690818_5 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 452.0
PYH1_k127_7690818_6 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 385.0
PYH1_k127_7690818_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000006363 142.0
PYH1_k127_7690818_8 Bacterial type II and III secretion system protein - - - 0.0000000000000000000000000001647 114.0
PYH1_k127_7713710_0 SMART Tetratricopeptide domain protein - - - 9.352e-320 985.0
PYH1_k127_7713710_1 transport system - - - 5.947e-269 839.0
PYH1_k127_7713710_2 Abc transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 443.0
PYH1_k127_7713710_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 438.0
PYH1_k127_7713710_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 436.0
PYH1_k127_7713710_5 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 330.0
PYH1_k127_7713710_6 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000287 132.0
PYH1_k127_7732208_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 7.686e-206 645.0
PYH1_k127_7732208_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001353 252.0
PYH1_k127_7732208_4 - - - - 0.0000879 45.0
PYH1_k127_7733976_0 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 305.0
PYH1_k127_7733976_1 PFAM beta-lactamase - - - 0.0000000003799 67.0
PYH1_k127_7764141_0 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 306.0
PYH1_k127_7764141_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000002304 131.0
PYH1_k127_7787479_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.413e-247 766.0
PYH1_k127_7787479_1 protein conserved in bacteria K09919 - - 4.348e-238 737.0
PYH1_k127_7787479_2 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 408.0
PYH1_k127_7826195_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0 1003.0
PYH1_k127_7826195_1 PFAM PhoH family protein K07175 - - 2.543e-305 936.0
PYH1_k127_7826195_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975,K03743 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008081,GO:0008104,GO:0008150,GO:0008452,GO:0008664,GO:0009966,GO:0010646,GO:0010738,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0023051,GO:0033036,GO:0034237,GO:0042578,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:0140098,GO:1902531 3.1.4.58,3.5.1.42 0.000000000000000000000000000000000000000000007223 169.0
PYH1_k127_7826195_11 Protein required for attachment to host cells - - - 0.00000000000000000000000000003776 116.0
PYH1_k127_7826195_2 major facilitator superfamily - - - 3.246e-247 766.0
PYH1_k127_7826195_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 557.0
PYH1_k127_7826195_4 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 430.0
PYH1_k127_7826195_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 373.0
PYH1_k127_7826195_6 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 368.0
PYH1_k127_7826195_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 293.0
PYH1_k127_7826195_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003458 252.0
PYH1_k127_7826195_9 - - - - 0.0000000000000000000000000000000000000000000000000000597 191.0
PYH1_k127_7834433_0 Atp-dependent helicase K03578 - 3.6.4.13 5.161e-211 657.0
PYH1_k127_7834433_1 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 428.0
PYH1_k127_7834433_2 Regulatory protein MarR - - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
PYH1_k127_7834433_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000008623 210.0
PYH1_k127_7834433_4 HPP family K07168 - - 0.0000000000000000000000000000000000000000000000000000000371 205.0
PYH1_k127_7834433_5 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000002467 195.0
PYH1_k127_7834433_6 - - - - 0.0000000000000000000000000000006774 129.0
PYH1_k127_7834433_7 Atp-dependent helicase K03578 - 3.6.4.13 0.000000002118 61.0
PYH1_k127_7850276_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1523.0
PYH1_k127_7850276_1 Peptidase M48 K06013 - 3.4.24.84 5.964e-250 773.0
PYH1_k127_7850276_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 367.0
PYH1_k127_7850276_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000001241 210.0
PYH1_k127_7850276_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000005456 74.0
PYH1_k127_7875457_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1115.0
PYH1_k127_7875457_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 9.049e-296 908.0
PYH1_k127_7875457_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 568.0
PYH1_k127_7875457_3 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 524.0
PYH1_k127_7875457_4 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
PYH1_k127_7875457_5 Preprotein translocase K03210 - - 0.00000000000000000000000000000000000000000000000007146 179.0
PYH1_k127_7926243_0 His Kinase A (phosphoacceptor) domain - - - 8.033e-246 782.0
PYH1_k127_7926243_1 SMART Signal transduction response regulator, receiver region K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 497.0
PYH1_k127_7934536_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 599.0
PYH1_k127_7934536_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 494.0
PYH1_k127_7934536_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 464.0
PYH1_k127_7934536_3 chemotaxis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 449.0
PYH1_k127_7934536_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000002591 250.0
PYH1_k127_7937717_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0 1416.0
PYH1_k127_7937717_1 Cytochrome c7 and related cytochrome c - - - 0.0 1152.0
PYH1_k127_7937717_2 Diguanylate cyclase - - - 9.473e-304 936.0
PYH1_k127_7937717_3 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 471.0
PYH1_k127_7937717_4 cytochrome complex assembly K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 392.0
PYH1_k127_7937717_5 Abc transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 371.0
PYH1_k127_7937717_6 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000000000000000000000000000000000000000000000000000000000001637 226.0
PYH1_k127_7963568_0 PFAM PhoH family protein K06217 - - 1.037e-194 608.0
PYH1_k127_7963568_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 593.0
PYH1_k127_7963568_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 307.0
PYH1_k127_7976503_0 K+ potassium transporter K03549 - - 2.334e-293 907.0
PYH1_k127_7976503_1 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 329.0
PYH1_k127_7978041_0 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 509.0
PYH1_k127_7978041_1 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 358.0
PYH1_k127_7978041_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 346.0
PYH1_k127_7978041_3 CNP1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 293.0
PYH1_k127_7978041_4 YqjK-like protein - - - 0.0000000003967 63.0
PYH1_k127_7988932_0 PFAM Transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 553.0
PYH1_k127_7995040_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1208.0
PYH1_k127_7995040_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.22e-286 880.0
PYH1_k127_7995040_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 442.0
PYH1_k127_7995040_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 404.0
PYH1_k127_7995040_4 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 289.0
PYH1_k127_7995040_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 282.0
PYH1_k127_7995040_6 rna-binding protein K07574 - - 0.00000000000000000000000000000000000000000000000000001187 189.0
PYH1_k127_8018230_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 476.0
PYH1_k127_8018230_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 418.0
PYH1_k127_8018230_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 400.0
PYH1_k127_8018230_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 384.0
PYH1_k127_8018230_4 Cytochrome c554 and c-prime - - - 0.000000000000000000000757 95.0
PYH1_k127_8025197_0 pilus assembly protein FimV K08086 - - 0.0 1465.0
PYH1_k127_8025197_1 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1139.0
PYH1_k127_8025197_10 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 571.0
PYH1_k127_8025197_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 525.0
PYH1_k127_8025197_12 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 523.0
PYH1_k127_8025197_13 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 491.0
PYH1_k127_8025197_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 396.0
PYH1_k127_8025197_15 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 390.0
PYH1_k127_8025197_16 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 377.0
PYH1_k127_8025197_17 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 327.0
PYH1_k127_8025197_18 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 305.0
PYH1_k127_8025197_19 PFAM Sporulation domain protein K03749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 305.0
PYH1_k127_8025197_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.491e-315 968.0
PYH1_k127_8025197_20 colicin v production K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 289.0
PYH1_k127_8025197_21 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000003266 213.0
PYH1_k127_8025197_22 - - - - 0.0000000000000092 77.0
PYH1_k127_8025197_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 8.617e-292 896.0
PYH1_k127_8025197_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.577e-263 811.0
PYH1_k127_8025197_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 5.721e-259 801.0
PYH1_k127_8025197_6 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.58e-249 771.0
PYH1_k127_8025197_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.656e-240 743.0
PYH1_k127_8025197_8 ErfK YbiS YcfS YnhG family protein - - - 1.772e-228 715.0
PYH1_k127_8025197_9 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 5.11e-225 699.0
PYH1_k127_8080100_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 1.119e-319 984.0
PYH1_k127_8080100_1 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 415.0
PYH1_k127_8080100_2 Isochorismate synthase K01851,K02361,K02552 - 5.4.4.2 0.0000000000001547 70.0
PYH1_k127_8130940_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.861e-238 737.0
PYH1_k127_8130940_1 TIGRFAM Diguanylate cyclase K13069,K21085 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 540.0
PYH1_k127_8130940_2 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000003669 167.0
PYH1_k127_8132125_0 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 6.315e-234 728.0
PYH1_k127_8132125_1 serine threonine protein kinase K12132 - 2.7.11.1 9.168e-230 719.0
PYH1_k127_8132125_2 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 541.0
PYH1_k127_8132125_3 dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 486.0
PYH1_k127_8132125_4 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 479.0
PYH1_k127_8132125_5 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 409.0
PYH1_k127_8132125_6 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 314.0
PYH1_k127_8132125_7 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000001397 244.0
PYH1_k127_8132125_8 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002206 242.0
PYH1_k127_8169820_0 Glycosyltransferase 36 associated - - - 4.317e-267 840.0
PYH1_k127_8169820_1 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000471 183.0
PYH1_k127_8196698_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 1.125e-312 959.0
PYH1_k127_8196698_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 436.0
PYH1_k127_8196698_2 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 329.0
PYH1_k127_8196698_3 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002272 234.0
PYH1_k127_8205921_0 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001743 278.0
PYH1_k127_8205921_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000001081 214.0
PYH1_k127_8205921_2 N-terminal domain of toast_rack, DUF2154 - - - 0.0000000000000000000000000000000000000002734 158.0
PYH1_k127_8205921_3 TAP-like protein - - - 0.00000000000000000000000000003636 122.0
PYH1_k127_8205921_4 metal-dependent membrane protease - - - 0.0000000000000000000224 100.0
PYH1_k127_8205921_5 Beta-lactamase - - - 0.00001418 50.0
PYH1_k127_8220287_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1349.0
PYH1_k127_8220287_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 529.0
PYH1_k127_8220287_2 mandelate racemase muconate lactonizing K01856,K01860,K02549,K19802,K21617,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20,5.1.1.22,5.5.1.1,5.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 529.0
PYH1_k127_8220287_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 494.0
PYH1_k127_8220287_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
PYH1_k127_8220287_5 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
PYH1_k127_8223118_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.271e-255 791.0
PYH1_k127_8223118_1 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 9.642e-216 671.0
PYH1_k127_8223118_2 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 419.0
PYH1_k127_826168_0 PFAM Glycosyl transferase, group 1 K00786 - - 6.208e-241 749.0
PYH1_k127_826168_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002422 259.0
PYH1_k127_826168_2 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000005672 142.0
PYH1_k127_8272186_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1189.0
PYH1_k127_8272186_1 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 537.0
PYH1_k127_8272186_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 475.0
PYH1_k127_8272186_3 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000000000000000009132 233.0
PYH1_k127_8278293_0 Sulfate permease family K03321 - - 7.295e-245 770.0
PYH1_k127_8278293_1 23S rRNA-intervening sequence protein - - - 0.0001643 45.0
PYH1_k127_8307030_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.412e-314 966.0
PYH1_k127_8307030_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 597.0
PYH1_k127_8307030_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 490.0
PYH1_k127_8307030_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 469.0
PYH1_k127_8307030_4 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 457.0
PYH1_k127_8307030_5 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 353.0
PYH1_k127_8307030_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004038 246.0
PYH1_k127_856325_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000002315 191.0
PYH1_k127_856325_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000002444 186.0
PYH1_k127_870659_0 Type II and III secretion system protein K02453 - - 5e-324 1001.0
PYH1_k127_870659_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.151e-262 811.0
PYH1_k127_870659_10 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 469.0
PYH1_k127_870659_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 425.0
PYH1_k127_870659_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 415.0
PYH1_k127_870659_13 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 411.0
PYH1_k127_870659_14 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 388.0
PYH1_k127_870659_15 toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 361.0
PYH1_k127_870659_16 ATPase activity, coupled to transmembrane movement of substances - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 347.0
PYH1_k127_870659_17 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 304.0
PYH1_k127_870659_18 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003976 267.0
PYH1_k127_870659_19 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000007535 216.0
PYH1_k127_870659_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.853e-260 803.0
PYH1_k127_870659_20 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000000003554 196.0
PYH1_k127_870659_21 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000000002149 192.0
PYH1_k127_870659_22 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000000000000004322 161.0
PYH1_k127_870659_23 response to antibiotic K07122 - - 0.00000000000000000000000000000000000000003049 156.0
PYH1_k127_870659_24 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000000000001081 139.0
PYH1_k127_870659_25 Protein of unknown function DUF72 - - - 0.0000000000000000000000004311 111.0
PYH1_k127_870659_26 type II secretion system protein E K02454,K02652,K12276 - - 0.0000122 48.0
PYH1_k127_870659_3 AAA domain - - - 6.909e-252 782.0
PYH1_k127_870659_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 6.385e-209 651.0
PYH1_k127_870659_5 Tetratricopeptide repeats - - - 9.077e-195 618.0
PYH1_k127_870659_6 abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 569.0
PYH1_k127_870659_7 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 516.0
PYH1_k127_870659_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 499.0
PYH1_k127_870659_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 492.0
PYH1_k127_870796_0 Extracellular solute-binding protein - - - 0.0 1407.0
PYH1_k127_870796_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 360.0
PYH1_k127_870796_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000001197 109.0
PYH1_k127_884486_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.772e-316 974.0
PYH1_k127_884486_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 6.432e-217 677.0
PYH1_k127_884486_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 9.956e-211 656.0
PYH1_k127_884486_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 565.0
PYH1_k127_884486_4 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 369.0
PYH1_k127_884486_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 289.0
PYH1_k127_884486_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
PYH1_k127_884486_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000004605 190.0
PYH1_k127_884486_8 - - - - 0.0000000000000000000000000000000001514 142.0
PYH1_k127_884486_9 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000001981 121.0
PYH1_k127_894995_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.243e-229 721.0
PYH1_k127_894995_1 Sodium:solute symporter family K14393 - - 0.0000000000000000000000000000000009662 131.0
PYH1_k127_894995_2 membrane - - - 0.00000000000000000000000000000003624 127.0
PYH1_k127_938949_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.183e-253 782.0
PYH1_k127_938949_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 555.0
PYH1_k127_938949_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 523.0
PYH1_k127_938949_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 431.0
PYH1_k127_938949_4 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 301.0
PYH1_k127_938949_5 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000000000000000006611 189.0
PYH1_k127_940361_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0 1047.0
PYH1_k127_940361_1 Peptidase family M48 - - - 2.968e-289 891.0
PYH1_k127_940361_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
PYH1_k127_940361_11 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000005201 142.0
PYH1_k127_940361_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.654e-269 829.0
PYH1_k127_940361_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 595.0
PYH1_k127_940361_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 543.0
PYH1_k127_940361_5 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 513.0
PYH1_k127_940361_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 330.0
PYH1_k127_940361_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002635 270.0
PYH1_k127_940361_8 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000002459 229.0
PYH1_k127_940361_9 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000003232 226.0
PYH1_k127_943920_0 Histidine kinase K07675,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 9.686e-238 750.0
PYH1_k127_943920_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 4.659e-211 657.0
PYH1_k127_943920_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 390.0
PYH1_k127_943920_3 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 348.0
PYH1_k127_987716_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.0 1397.0
PYH1_k127_987716_1 Sodium:solute symporter family K14393 - - 2.225e-304 951.0
PYH1_k127_987716_2 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 496.0
PYH1_k127_987716_3 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 308.0
PYH1_k127_987716_4 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000000006563 175.0
PYH1_k127_994717_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0 1280.0
PYH1_k127_994717_1 - - - - 4.281e-229 711.0
PYH1_k127_994717_2 Putative metallopeptidase domain - - - 7.678e-217 674.0
PYH1_k127_994717_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 6.667e-213 662.0
PYH1_k127_994717_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 443.0
PYH1_k127_994717_5 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 439.0
PYH1_k127_994717_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 390.0
PYH1_k127_994717_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 387.0
PYH1_k127_994717_8 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 359.0
PYH1_k127_994717_9 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 340.0