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Overview

ID MAG03148
Name PYH1_bin.42
Sample SMP0073
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class DTKX01
Order DTKX01
Family GCA-020343715
Genus
Species
Assembly information
Completeness (%) 72.02
Contamination (%) 1.08
GC content (%) 68.0
N50 (bp) 4,508
Genome size (bp) 2,464,178

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1797

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1002165_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 384.0
PYH1_k127_1002165_1 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000000000000000000000000000000000000001407 158.0
PYH1_k127_1002165_2 - - - - 0.00003934 46.0
PYH1_k127_1005387_0 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 408.0
PYH1_k127_1005387_1 ferredoxin oxidoreductase, subunit beta K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 353.0
PYH1_k127_1005387_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 293.0
PYH1_k127_1005387_3 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 290.0
PYH1_k127_1005387_4 PFAM Pyruvate K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000007132 164.0
PYH1_k127_1005387_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000004456 146.0
PYH1_k127_1005387_6 PFAM Pyruvate K00177 - 1.2.7.3 0.0000000000000000000000000000001966 129.0
PYH1_k127_1005387_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00001732 52.0
PYH1_k127_1009485_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 429.0
PYH1_k127_1033779_0 self proteolysis K21449 - - 0.0000000000000000000000009259 123.0
PYH1_k127_1033779_1 Belongs to the ompA family K20276 - - 0.000000000001791 82.0
PYH1_k127_1054680_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 411.0
PYH1_k127_1054680_1 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0000000000000000000000000001368 127.0
PYH1_k127_1056054_0 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000003484 117.0
PYH1_k127_1056054_1 N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 - 2.1.1.215,2.1.1.216 0.0000002514 55.0
PYH1_k127_1060436_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 610.0
PYH1_k127_1060436_1 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000001729 139.0
PYH1_k127_1074259_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000164 300.0
PYH1_k127_1089061_0 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000008085 183.0
PYH1_k127_1089061_1 Nudix (nucleoside diphosphate linked moiety X)-type motif 18 K17817 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009132,GO:0009134,GO:0009135,GO:0009137,GO:0009150,GO:0009151,GO:0009154,GO:0009155,GO:0009164,GO:0009166,GO:0009179,GO:0009181,GO:0009182,GO:0009184,GO:0009185,GO:0009186,GO:0009191,GO:0009192,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044715,GO:0044716,GO:0044717,GO:0046056,GO:0046057,GO:0046066,GO:0046067,GO:0046128,GO:0046130,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046710,GO:0046712,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.58 0.0001442 49.0
PYH1_k127_1102368_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.043e-240 759.0
PYH1_k127_1102368_1 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 376.0
PYH1_k127_1102368_2 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000003721 212.0
PYH1_k127_1102368_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000005659 196.0
PYH1_k127_1102368_4 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000007675 163.0
PYH1_k127_1102368_5 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000001316 122.0
PYH1_k127_1102904_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002144 276.0
PYH1_k127_1102904_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000005368 229.0
PYH1_k127_1102904_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000001799 178.0
PYH1_k127_1102904_3 Glycine cleavage system H protein K02437 - - 0.000000000000000000000000000000003278 137.0
PYH1_k127_1102904_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000004905 104.0
PYH1_k127_1106814_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 333.0
PYH1_k127_1106814_1 dTDP-glucose pyrophosphorylase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000001964 218.0
PYH1_k127_1124121_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 383.0
PYH1_k127_1124121_1 TRAM domain - - - 0.000000000000008892 77.0
PYH1_k127_1124121_2 - - - - 0.0000000006438 64.0
PYH1_k127_1128104_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 342.0
PYH1_k127_1128104_1 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 329.0
PYH1_k127_1128104_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000303 237.0
PYH1_k127_1128104_3 PFAM PKD domain containing protein - - - 0.00000000000001993 88.0
PYH1_k127_1128104_4 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000179 59.0
PYH1_k127_1174932_0 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 398.0
PYH1_k127_1174932_1 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000002458 242.0
PYH1_k127_1174932_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000002799 109.0
PYH1_k127_1174932_3 4Fe-4S binding domain - - - 0.00000000000000000008562 90.0
PYH1_k127_1174932_4 Lrp/AsnC ligand binding domain - - - 0.000003207 54.0
PYH1_k127_1198235_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000009837 197.0
PYH1_k127_1198235_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000001241 179.0
PYH1_k127_1198235_2 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000004171 171.0
PYH1_k127_1198235_3 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000004496 163.0
PYH1_k127_1198235_4 CBS domain K03699 - - 0.0000000000000000000000000000000000000001075 164.0
PYH1_k127_1198235_5 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000739 126.0
PYH1_k127_1198235_6 Xylose isomerase domain protein TIM barrel - - - 0.00000000001205 72.0
PYH1_k127_1205200_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 344.0
PYH1_k127_1205200_1 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000002372 74.0
PYH1_k127_1205200_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000003186 63.0
PYH1_k127_1205200_3 PFAM Ribosomal LX protein K02944 - - 0.000001607 55.0
PYH1_k127_1214442_0 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 312.0
PYH1_k127_1214442_1 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 314.0
PYH1_k127_1214442_2 shikimate kinase activity K00891 - 2.7.1.71 0.00000302 56.0
PYH1_k127_1216031_0 Protein of unknown function (DUF1646) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002617 280.0
PYH1_k127_1216031_1 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000002582 190.0
PYH1_k127_1225335_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 402.0
PYH1_k127_1225335_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000001764 160.0
PYH1_k127_1225335_2 PFAM DNA polymerase beta domain protein region K07075 - - 0.0000000000000000000001336 100.0
PYH1_k127_1225335_3 Protein of unknown function DUF86 K07075 - - 0.0000000000000000001074 91.0
PYH1_k127_1226086_0 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 380.0
PYH1_k127_1226086_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000002084 67.0
PYH1_k127_1226086_2 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00001716 56.0
PYH1_k127_1241599_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000002401 98.0
PYH1_k127_1243206_0 Heat shock 70 kDa protein K04043 - - 2.599e-248 780.0
PYH1_k127_1243206_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000597 109.0
PYH1_k127_1243206_2 Membrane protein of unknown function DUF63 - - - 0.000000000000000001979 91.0
PYH1_k127_1248710_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 395.0
PYH1_k127_1248710_1 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 376.0
PYH1_k127_1248710_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001351 248.0
PYH1_k127_1248710_3 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002913 273.0
PYH1_k127_1248710_4 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000000000000000000000002616 163.0
PYH1_k127_1256964_0 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000001888 170.0
PYH1_k127_1256964_1 Transcriptional regulator K07730 - - 0.000000000000000000000000000000004508 140.0
PYH1_k127_1256964_2 PFAM ABC transporter related K16785,K16786,K16787 - - 0.000000000000000000000002994 105.0
PYH1_k127_1256964_3 amino acid activation for nonribosomal peptide biosynthetic process K12132 - 2.7.11.1 0.000000000000002586 90.0
PYH1_k127_1256964_4 skeletal muscle myosin thick filament assembly K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.0000000000000322 78.0
PYH1_k127_1256964_5 PFAM PKD domain containing protein - - - 0.000399 53.0
PYH1_k127_1256964_6 transcriptional regulator K07172 - - 0.0008038 46.0
PYH1_k127_1294094_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 587.0
PYH1_k127_1294094_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000005459 229.0
PYH1_k127_1294094_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000002067 162.0
PYH1_k127_1294094_3 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000005237 159.0
PYH1_k127_1294094_4 NMT1-like family K02051 - - 0.00000000000000000000000000000000000001168 158.0
PYH1_k127_1294094_5 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000001109 71.0
PYH1_k127_1299971_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000002315 92.0
PYH1_k127_1301952_0 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000002088 115.0
PYH1_k127_1302212_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000009749 209.0
PYH1_k127_1302212_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000005546 94.0
PYH1_k127_1327312_0 Winged helix-turn-helix DNA-binding - - - 0.00001694 53.0
PYH1_k127_1332473_0 FG-GAP repeat - - - 0.0000000002317 76.0
PYH1_k127_133993_0 TPR Domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000009953 217.0
PYH1_k127_1343709_0 carboxypeptidase K05996 - 3.4.17.18 0.00000000000000003334 89.0
PYH1_k127_1343709_1 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000007156 90.0
PYH1_k127_1348238_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 320.0
PYH1_k127_1348238_1 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000001803 204.0
PYH1_k127_137961_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 317.0
PYH1_k127_137961_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000001173 188.0
PYH1_k127_1414416_0 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000003804 74.0
PYH1_k127_1414416_1 Bacterial Ig-like domain (group 3) - - - 0.0005704 48.0
PYH1_k127_144525_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 397.0
PYH1_k127_144525_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000003891 205.0
PYH1_k127_144525_2 Polynucleotide kinase 3 phosphatase - - - 0.0000000000000000000000000000000000000000002085 167.0
PYH1_k127_144525_3 - - - - 0.00000000000000000000000000001103 136.0
PYH1_k127_144525_4 protein conserved in archaea K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.000001178 56.0
PYH1_k127_1448426_0 Domain of unknown function (DUF4114) - - - 0.0000000000001271 85.0
PYH1_k127_1448426_1 Belongs to the glycosyl hydrolase family 6 - - - 0.0000006431 63.0
PYH1_k127_1461464_0 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
PYH1_k127_1461464_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000008921 233.0
PYH1_k127_1461464_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000001869 189.0
PYH1_k127_1461464_3 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000006214 159.0
PYH1_k127_14630_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 307.0
PYH1_k127_14630_1 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000002761 82.0
PYH1_k127_1467328_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 2.167e-244 762.0
PYH1_k127_1467328_1 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 468.0
PYH1_k127_1478737_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 316.0
PYH1_k127_1478737_1 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
PYH1_k127_1478737_2 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000001036 176.0
PYH1_k127_1478737_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000007692 109.0
PYH1_k127_1478737_4 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000009364 81.0
PYH1_k127_1482786_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1168.0
PYH1_k127_1537133_0 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 533.0
PYH1_k127_1537133_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 384.0
PYH1_k127_1537133_2 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000002087 219.0
PYH1_k127_1537133_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000001992 150.0
PYH1_k127_1537133_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000004752 73.0
PYH1_k127_1541100_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.95e-204 651.0
PYH1_k127_1558160_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 598.0
PYH1_k127_1558160_1 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 328.0
PYH1_k127_1558160_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000001391 201.0
PYH1_k127_1558160_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000003437 183.0
PYH1_k127_1558160_4 Psort location CytoplasmicMembrane, score K16927 - - 0.000000000000000000000000000000000000000009769 166.0
PYH1_k127_1558160_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000001255 69.0
PYH1_k127_1563615_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000002657 119.0
PYH1_k127_1580474_0 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
PYH1_k127_1580474_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000136 198.0
PYH1_k127_1580474_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000005134 105.0
PYH1_k127_1591282_0 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.0000000000000000000000000000000001746 145.0
PYH1_k127_1591282_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000327 68.0
PYH1_k127_1591282_2 FR47-like protein - - - 0.0000001147 61.0
PYH1_k127_1600541_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 452.0
PYH1_k127_1600541_1 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000001177 206.0
PYH1_k127_1600541_2 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000005969 146.0
PYH1_k127_1618875_0 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000005975 132.0
PYH1_k127_1618875_1 ABC transporter K02003 - - 0.0000000000000000006789 88.0
PYH1_k127_1618875_2 FtsX-like permease family K02004 - - 0.000000006517 70.0
PYH1_k127_1624983_0 Tetratricopeptide repeat - - - 0.000001436 59.0
PYH1_k127_1628739_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000001184 171.0
PYH1_k127_1628739_1 Enolase, N-terminal domain K01689 - 4.2.1.11 0.0008741 42.0
PYH1_k127_1636374_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 523.0
PYH1_k127_1636374_1 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 418.0
PYH1_k127_1636374_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 419.0
PYH1_k127_1636374_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
PYH1_k127_1636374_4 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 385.0
PYH1_k127_1636374_5 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
PYH1_k127_1636374_6 FMN-dependent alpha-hydroxy acid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 339.0
PYH1_k127_1636374_7 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001046 254.0
PYH1_k127_1636374_8 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000007985 208.0
PYH1_k127_1636374_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000003126 99.0
PYH1_k127_1656274_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 334.0
PYH1_k127_1656274_1 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000001321 151.0
PYH1_k127_1661310_0 Acetyltransferase (GNAT) domain - - - 0.0000000004737 64.0
PYH1_k127_1679998_0 myosin light chain kinase activity K12567 - 2.7.11.1 0.00000000000000000000000165 121.0
PYH1_k127_1686332_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 458.0
PYH1_k127_1686332_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000001462 151.0
PYH1_k127_1690253_0 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000001098 126.0
PYH1_k127_1690253_1 Parallel beta-helix repeats - - - 0.000002905 61.0
PYH1_k127_1690253_2 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.00003498 57.0
PYH1_k127_1725482_0 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000004559 99.0
PYH1_k127_1725656_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000132 295.0
PYH1_k127_1725656_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000003478 160.0
PYH1_k127_1725656_2 PRC-barrel domain - - - 0.0000000000000000000473 94.0
PYH1_k127_1725656_3 - - - - 0.0002316 45.0
PYH1_k127_1725656_4 chlorophyll binding - - - 0.0006026 52.0
PYH1_k127_17267_0 electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 442.0
PYH1_k127_17267_1 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 288.0
PYH1_k127_17267_2 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000003384 104.0
PYH1_k127_1727017_0 Creatinine amidohydrolase K01470 - 3.5.2.10 5.13e-296 929.0
PYH1_k127_1742627_0 HELICc2 K03722,K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 385.0
PYH1_k127_1742627_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000113 76.0
PYH1_k127_1745141_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 349.0
PYH1_k127_1745141_1 PA14 domain - - - 0.00000000000000000000000000000000004544 157.0
PYH1_k127_1745141_2 Fibronectin type III domain - - - 0.0000000000000000000000000000007314 130.0
PYH1_k127_1745954_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000005613 235.0
PYH1_k127_1745954_1 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.0000000000000000000000000000000005909 143.0
PYH1_k127_1745954_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0001268 44.0
PYH1_k127_1764903_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 380.0
PYH1_k127_1764903_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 295.0
PYH1_k127_1764903_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008754 211.0
PYH1_k127_1780863_0 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00002357 57.0
PYH1_k127_1781916_0 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005797 282.0
PYH1_k127_1781916_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000001826 179.0
PYH1_k127_1781916_2 Metallopeptidase family M24 K01271 - 3.4.13.9 0.0000000000000001298 89.0
PYH1_k127_1787131_0 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000013 204.0
PYH1_k127_1792523_0 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001653 248.0
PYH1_k127_1792523_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K13605 - 2.5.1.133,2.5.1.62 0.00000000000000000000007814 115.0
PYH1_k127_1792523_2 membrane - GO:0005575,GO:0016020 - 0.00003653 57.0
PYH1_k127_1797669_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000006766 160.0
PYH1_k127_1797669_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000003053 161.0
PYH1_k127_1797669_2 Molybdopterin converting factor K03635 - 2.8.1.12 0.0000000000000000000000003227 121.0
PYH1_k127_1797669_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0009015 46.0
PYH1_k127_1802000_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000004741 174.0
PYH1_k127_1802000_1 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000007527 71.0
PYH1_k127_1802000_2 SCP-2 sterol transfer family - - - 0.0000000003593 64.0
PYH1_k127_1802000_3 Belongs to the ompA family K20276 - - 0.0000002903 64.0
PYH1_k127_1802000_4 Protein of unknown function (DUF2721) - - - 0.0000004765 59.0
PYH1_k127_1805220_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
PYH1_k127_1805220_1 Titin Z K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.000000000000379 84.0
PYH1_k127_1812085_0 Subtilase family K01361 - 3.4.21.96 0.00000000001356 79.0
PYH1_k127_1812085_1 protein conserved in archaea - - - 0.00000000007072 77.0
PYH1_k127_1814276_0 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 309.0
PYH1_k127_1814276_1 Membrane - - - 0.000000000000000000000000000000000003244 147.0
PYH1_k127_1855314_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 353.0
PYH1_k127_1855314_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007256 291.0
PYH1_k127_1855314_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000007124 218.0
PYH1_k127_1857524_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000001742 256.0
PYH1_k127_1857524_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000001553 164.0
PYH1_k127_1857524_2 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000007007 105.0
PYH1_k127_1857524_3 CarboxypepD_reg-like domain K13276 - - 0.00000000000004537 87.0
PYH1_k127_1857524_4 Domain of unknown function (DUF4350) - - - 0.00003312 56.0
PYH1_k127_1857524_5 NUDIX domain K03574 - 3.6.1.55 0.00004802 47.0
PYH1_k127_1874101_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000004179 108.0
PYH1_k127_1874101_1 Fibronectin type III domain - - - 0.00000000000000001023 100.0
PYH1_k127_1874101_2 metallopeptidase activity - - - 0.0000000001496 76.0
PYH1_k127_187980_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 431.0
PYH1_k127_187980_1 PFAM GvpD gas vesicle - - - 0.000000000000000000000000000000000000000236 168.0
PYH1_k127_187980_2 TPR Domain containing protein - - - 0.0000000000000000000000000000000004514 140.0
PYH1_k127_1881273_0 Glycosyl hydrolases family 18 - - - 0.00000000001719 78.0
PYH1_k127_1882806_0 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000008744 220.0
PYH1_k127_1882806_1 Cupin domain - - - 0.0000000000000000000000000000000000001545 148.0
PYH1_k127_1882806_2 response to heat - - - 0.00000000008665 66.0
PYH1_k127_1887822_0 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000004443 171.0
PYH1_k127_1889356_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 383.0
PYH1_k127_1889356_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000004248 187.0
PYH1_k127_1889356_2 FlgD Ig-like domain K15924 - 3.2.1.136 0.000000000000000000000000000000001304 149.0
PYH1_k127_1889356_3 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000004383 144.0
PYH1_k127_1889356_4 Helix-turn-helix domain - - - 0.00000000000006611 76.0
PYH1_k127_1889356_5 von willebrand factor, type A K20276 - - 0.000000000007755 79.0
PYH1_k127_1895151_0 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 379.0
PYH1_k127_1895151_1 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000000000000004379 216.0
PYH1_k127_1918229_0 PFAM methyltransferase K07755 - 2.1.1.137 0.00000003508 60.0
PYH1_k127_1927887_0 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 477.0
PYH1_k127_1927887_1 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000008424 220.0
PYH1_k127_1927887_2 membrane-associated protein domain - - - 0.0000000000000769 84.0
PYH1_k127_1937358_0 Double zinc ribbon - - - 0.0001477 55.0
PYH1_k127_1948451_0 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000008671 227.0
PYH1_k127_1948451_1 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000002896 186.0
PYH1_k127_1948451_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000001159 184.0
PYH1_k127_1960060_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
PYH1_k127_1960060_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000001084 133.0
PYH1_k127_1960060_3 - - - - 0.00000000000000000000000391 105.0
PYH1_k127_1960060_5 SpoVT / AbrB like domain - - - 0.000000000000282 76.0
PYH1_k127_1960060_6 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.0000000003248 75.0
PYH1_k127_1963042_0 amine dehydrogenase activity - - - 0.0000000000000001398 96.0
PYH1_k127_1963042_1 Psort location Extracellular, score - - - 0.0000000000178 79.0
PYH1_k127_1982618_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.375e-209 661.0
PYH1_k127_1982618_1 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000006054 161.0
PYH1_k127_1982618_2 Thioredoxin K03671 - - 0.0000000000000000000000000000008784 137.0
PYH1_k127_1982618_3 flavin reductase - - - 0.00000000000000000000000000002382 124.0
PYH1_k127_1982618_4 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000009453 113.0
PYH1_k127_1982618_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000001318 115.0
PYH1_k127_1982618_6 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000006658 117.0
PYH1_k127_1988901_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 368.0
PYH1_k127_1988901_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000001442 81.0
PYH1_k127_1989191_0 Transglutaminase-like - - - 0.000000000000000007027 100.0
PYH1_k127_1989191_1 Archaeal Nre, N-terminal - - - 0.0003546 51.0
PYH1_k127_1992455_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 473.0
PYH1_k127_1992455_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000598 202.0
PYH1_k127_1992455_2 Pfam:DUF552 K09152 - - 0.0000000000000298 79.0
PYH1_k127_1992455_3 metallopeptidase activity - - - 0.0000000000001252 82.0
PYH1_k127_1992455_4 Archaeal Type IV pilin, N-terminal - - - 0.00007374 57.0
PYH1_k127_1992469_0 Protein of unknown function (DUF1566) - - - 0.0000007127 63.0
PYH1_k127_2004434_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 393.0
PYH1_k127_2004434_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
PYH1_k127_2004434_2 Protein of unknown function (DUF424) K09148 - - 0.0000000000000001022 94.0
PYH1_k127_2004434_3 - K00960 - 2.7.7.6 0.000000000000001737 77.0
PYH1_k127_2036742_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003213 277.0
PYH1_k127_2036742_1 Belongs to the UPF0218 family K09735 - - 0.000000000000000000001787 102.0
PYH1_k127_2036742_2 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000002066 82.0
PYH1_k127_2036742_3 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000611 81.0
PYH1_k127_2036742_4 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000001125 66.0
PYH1_k127_2036742_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000015 67.0
PYH1_k127_2054224_0 Peptidase S8 K08651 - 3.4.21.66 0.000002697 61.0
PYH1_k127_2062940_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006728 295.0
PYH1_k127_2073637_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 457.0
PYH1_k127_2073637_1 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000000000000000000003356 120.0
PYH1_k127_2073637_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000003797 117.0
PYH1_k127_2091825_0 FG-GAP repeat - - - 0.00000000001626 79.0
PYH1_k127_2093039_0 calcium- and calmodulin-responsive adenylate cyclase activity K20276 - - 0.0000000000000000000002095 113.0
PYH1_k127_2093062_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007053 258.0
PYH1_k127_2147703_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000002285 151.0
PYH1_k127_2156359_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000006388 85.0
PYH1_k127_2178760_0 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000009718 189.0
PYH1_k127_2178760_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000007051 158.0
PYH1_k127_2178760_2 Integral membrane protein DUF106 - - - 0.000000000000000000004557 102.0
PYH1_k127_2191529_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 417.0
PYH1_k127_2191529_1 alginic acid biosynthetic process - - - 0.00001586 59.0
PYH1_k127_2227030_0 PhoU domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001023 240.0
PYH1_k127_2227030_1 low molecular weight K03741,K18701 - 1.20.4.1,2.8.4.2 0.000000000000000000000000000000278 128.0
PYH1_k127_2227030_2 protein conserved in archaea - - - 0.000000000004825 72.0
PYH1_k127_2245049_0 Integrin alpha (beta-propellor repeats). - - - 0.000000000000001583 91.0
PYH1_k127_2250446_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1038.0
PYH1_k127_2250446_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 407.0
PYH1_k127_2250446_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 336.0
PYH1_k127_2250446_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000000000000000000000002076 193.0
PYH1_k127_2250446_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000008889 188.0
PYH1_k127_2252291_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 354.0
PYH1_k127_2252291_1 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 349.0
PYH1_k127_2252291_2 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
PYH1_k127_2252291_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000008039 214.0
PYH1_k127_2270309_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000123 94.0
PYH1_k127_2282321_0 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000008978 184.0
PYH1_k127_2282321_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000001505 178.0
PYH1_k127_2282321_2 Transcriptional regulator - - - 0.000000000000000009903 98.0
PYH1_k127_2285256_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000064 171.0
PYH1_k127_2285256_1 PKD domain - - - 0.00000000000004908 86.0
PYH1_k127_2285361_0 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002446 276.0
PYH1_k127_2285361_1 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
PYH1_k127_2298803_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 442.0
PYH1_k127_2298803_1 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000104 203.0
PYH1_k127_2305758_0 Subtilase family K01361 - 3.4.21.96 0.00005792 56.0
PYH1_k127_2322037_0 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 370.0
PYH1_k127_2322037_1 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000004706 246.0
PYH1_k127_2322037_10 Cupin 2, conserved barrel domain protein - - - 0.0000001546 62.0
PYH1_k127_2322037_11 Belongs to the ompA family K20276 - - 0.0000005863 64.0
PYH1_k127_2322037_12 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0004845 45.0
PYH1_k127_2322037_2 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000007279 213.0
PYH1_k127_2322037_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000004565 192.0
PYH1_k127_2322037_4 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000004575 164.0
PYH1_k127_2322037_5 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000002571 117.0
PYH1_k127_2322037_6 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.00000000000000000000002725 108.0
PYH1_k127_2322037_7 PFAM glutaredoxin K06191 - - 0.00000000000000000001369 95.0
PYH1_k127_2322037_8 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000006414 87.0
PYH1_k127_2322037_9 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000004482 76.0
PYH1_k127_2325599_0 Carboxyl transferase domain - - - 5.45e-235 741.0
PYH1_k127_2325599_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 531.0
PYH1_k127_2325599_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 352.0
PYH1_k127_2325599_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000329 288.0
PYH1_k127_2325599_4 Biotin-requiring enzyme K02160 - - 0.00000000000000000001407 92.0
PYH1_k127_2329925_1 Di-glucose binding within endoplasmic reticulum - - - 0.000001326 62.0
PYH1_k127_2349894_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 508.0
PYH1_k127_2349894_1 Molybdopterin converting factor, small subunit K03636 - - 0.000003062 52.0
PYH1_k127_2369324_0 glycoside hydrolase, family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002294 273.0
PYH1_k127_2370631_0 C-terminal region of MMR_HSR1 domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 407.0
PYH1_k127_2370631_1 alpha beta - - - 0.0000001609 64.0
PYH1_k127_238053_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000005773 164.0
PYH1_k127_2381533_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 322.0
PYH1_k127_2381533_1 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000001159 131.0
PYH1_k127_2381533_2 cheY-homologous receiver domain - - - 0.00000000000000000000636 104.0
PYH1_k127_2381533_3 PFAM Roadblock LC7 family protein K07131 - - 0.0000004509 57.0
PYH1_k127_2381533_4 4-vinyl reductase, 4VR - - - 0.00005781 55.0
PYH1_k127_2392724_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 452.0
PYH1_k127_2392724_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 415.0
PYH1_k127_2392724_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000001753 138.0
PYH1_k127_2395682_0 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000313 207.0
PYH1_k127_2395682_1 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000002938 147.0
PYH1_k127_2395682_2 TPR Domain containing protein - - - 0.000000000000000000002315 104.0
PYH1_k127_2403092_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002437 289.0
PYH1_k127_2403092_1 OmpA family - - - 0.000000000000247 82.0
PYH1_k127_2406800_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000001082 173.0
PYH1_k127_2406800_1 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 0.000000000006114 69.0
PYH1_k127_2407314_0 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000002339 236.0
PYH1_k127_2407314_1 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000002104 213.0
PYH1_k127_2409243_0 PFAM FecR protein K20276 - - 0.0000000000002763 84.0
PYH1_k127_2411827_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.476e-239 754.0
PYH1_k127_2411827_1 Oxaloacetate decarboxylase K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 525.0
PYH1_k127_2411827_2 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000002769 61.0
PYH1_k127_2415241_0 PFAM NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 382.0
PYH1_k127_2415241_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000147 139.0
PYH1_k127_2415241_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.25 0.00000000000000000000000000000247 127.0
PYH1_k127_2415241_3 domain, Protein - - - 0.00000000000000001364 98.0
PYH1_k127_2415241_4 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000001988 61.0
PYH1_k127_2415241_5 Nucleotidyltransferase domain - - - 0.000005314 57.0
PYH1_k127_2420621_0 PKD domain - - - 0.0000000001371 75.0
PYH1_k127_2436238_0 Molybdopterin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002749 295.0
PYH1_k127_2436238_1 COG0437 Fe-S-cluster-containing hydrogenase components 1 K00184 - - 0.0000000000000000000000008835 106.0
PYH1_k127_2445327_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 471.0
PYH1_k127_2445327_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008842 271.0
PYH1_k127_2445327_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000002442 243.0
PYH1_k127_2445327_3 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000004723 91.0
PYH1_k127_2445327_4 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000807 79.0
PYH1_k127_2458817_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 521.0
PYH1_k127_2458817_1 Transcriptional regulator, ArsR family - - - 0.000000000002185 80.0
PYH1_k127_2459840_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000002043 114.0
PYH1_k127_2461672_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001951 259.0
PYH1_k127_2461826_0 - - - - 0.0000000000000000000000000000000000000000000000003028 196.0
PYH1_k127_2469973_0 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 470.0
PYH1_k127_2469973_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004222 276.0
PYH1_k127_2469973_2 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000003192 166.0
PYH1_k127_2475260_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000302 129.0
PYH1_k127_2475260_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00002461 49.0
PYH1_k127_2488667_0 pfam abc1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 306.0
PYH1_k127_2488667_1 PFAM Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000008101 205.0
PYH1_k127_2488667_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000007113 63.0
PYH1_k127_2496655_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
PYH1_k127_2496655_1 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000006953 268.0
PYH1_k127_2496655_2 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000002146 231.0
PYH1_k127_2496655_3 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000007864 214.0
PYH1_k127_2496655_4 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000005451 164.0
PYH1_k127_2500545_0 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002022 299.0
PYH1_k127_2505012_0 6-phosphogluconolactonase activity - - - 0.0000000000000000000299 107.0
PYH1_k127_2508286_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 557.0
PYH1_k127_2508286_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
PYH1_k127_2508286_2 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002415 254.0
PYH1_k127_2508286_3 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000008784 154.0
PYH1_k127_2509402_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 439.0
PYH1_k127_2509402_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 374.0
PYH1_k127_2509402_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000001471 216.0
PYH1_k127_2509402_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000001532 186.0
PYH1_k127_2509402_4 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171,K00188 - 1.2.7.1,1.2.7.7 0.0000000000000000000000003117 107.0
PYH1_k127_2509402_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000002463 106.0
PYH1_k127_2509402_6 Protein of unknown function (DUF835) - - - 0.0000000744 61.0
PYH1_k127_2509402_7 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0000003433 63.0
PYH1_k127_2516784_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000001881 180.0
PYH1_k127_2516784_1 Flavodoxin - - - 0.000000000000000000000001276 107.0
PYH1_k127_2523846_0 TIGRFAM conserved repeat domain protein - - - 0.00000978 59.0
PYH1_k127_2531495_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 552.0
PYH1_k127_2531495_1 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 535.0
PYH1_k127_2531495_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
PYH1_k127_2531495_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000006866 214.0
PYH1_k127_2531495_4 4Fe-4S binding domain - - - 0.0000001181 54.0
PYH1_k127_2543139_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.337e-249 781.0
PYH1_k127_2543139_1 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000001282 159.0
PYH1_k127_2543139_2 DNA binding protein K06930 - - 0.0000000000000000000000000000006151 130.0
PYH1_k127_2543139_3 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000002664 124.0
PYH1_k127_2543139_4 Protein conserved in bacteria - - - 0.0000000000000000000000000001964 119.0
PYH1_k127_2554709_0 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000000000000004267 216.0
PYH1_k127_2561469_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
PYH1_k127_2561469_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000003191 237.0
PYH1_k127_2561469_2 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000001521 164.0
PYH1_k127_2561469_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000001015 78.0
PYH1_k127_2566098_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 337.0
PYH1_k127_2566098_1 skeletal muscle myosin thick filament assembly K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.00000000000000000000000000003679 138.0
PYH1_k127_2586079_0 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.000000001945 72.0
PYH1_k127_2591399_0 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 602.0
PYH1_k127_2591399_1 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000006892 220.0
PYH1_k127_2591399_2 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000004669 202.0
PYH1_k127_2591399_3 PKD domain - - - 0.000000000000000000000000005655 127.0
PYH1_k127_2591399_4 Alpha-L-arabinofuranosidase C-terminal domain - - - 0.000000000000000000000000007159 127.0
PYH1_k127_2591399_5 PFAM PKD domain containing protein - - - 0.0000000000000009663 87.0
PYH1_k127_2594230_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 516.0
PYH1_k127_2594230_1 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000001619 186.0
PYH1_k127_2594230_2 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000001233 189.0
PYH1_k127_2594230_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000001106 61.0
PYH1_k127_2601284_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 304.0
PYH1_k127_2601284_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.000000006681 57.0
PYH1_k127_2607457_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 369.0
PYH1_k127_2607457_1 metallopeptidase activity K01081,K01183,K20276 - 3.1.3.5,3.2.1.14 0.0000000003842 71.0
PYH1_k127_2613240_0 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000003709 226.0
PYH1_k127_2613240_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00000000000000000000000000000000000000000000000000008446 196.0
PYH1_k127_2613240_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000005288 172.0
PYH1_k127_2613240_3 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000001846 112.0
PYH1_k127_2613240_4 Subtilase family - - - 0.00000806 57.0
PYH1_k127_2626868_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000005124 126.0
PYH1_k127_2638963_0 Belongs to the CarB family K01955 - 6.3.5.5 6.906e-317 991.0
PYH1_k127_2638963_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000001151 213.0
PYH1_k127_2663140_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 351.0
PYH1_k127_2663280_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 409.0
PYH1_k127_2663280_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000001039 172.0
PYH1_k127_2663280_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000002846 152.0
PYH1_k127_2663280_3 NUDIX domain - - - 0.0000000000000000000000000000252 122.0
PYH1_k127_2663280_4 Trm112p-like protein - - - 0.000000000002908 73.0
PYH1_k127_2671151_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 534.0
PYH1_k127_2671151_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000253 289.0
PYH1_k127_2671151_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000003465 191.0
PYH1_k127_2671151_3 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000001281 171.0
PYH1_k127_2671151_4 ribosomal small subunit binding - - - 0.000001035 59.0
PYH1_k127_2687239_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 422.0
PYH1_k127_2687239_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000429 205.0
PYH1_k127_2687239_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000002911 179.0
PYH1_k127_2687346_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
PYH1_k127_2687346_1 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 356.0
PYH1_k127_2687346_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 302.0
PYH1_k127_2687346_3 zinc-ribbon domain - - - 0.0003834 46.0
PYH1_k127_2689194_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.039e-220 703.0
PYH1_k127_2689194_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 400.0
PYH1_k127_2689194_2 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 357.0
PYH1_k127_2689194_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 296.0
PYH1_k127_2689194_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002089 295.0
PYH1_k127_2689194_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000002661 139.0
PYH1_k127_2689194_6 Protein conserved in bacteria K07192 - - 0.00000000000000000709 91.0
PYH1_k127_2700268_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 398.0
PYH1_k127_2700268_1 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000007236 159.0
PYH1_k127_2705784_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000004259 195.0
PYH1_k127_2705784_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000001896 98.0
PYH1_k127_2710895_0 PFAM Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 421.0
PYH1_k127_2710895_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 339.0
PYH1_k127_2710895_2 Serine aminopeptidase, S33 - - - 0.00000004287 59.0
PYH1_k127_2712131_0 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000008391 253.0
PYH1_k127_2712131_1 archaeal coiled-coil protein - - - 0.000000000000000000002248 109.0
PYH1_k127_2712131_2 Di-glucose binding within endoplasmic reticulum - - - 0.00002808 55.0
PYH1_k127_2712131_3 Protein of unknown function (DUF835) - - - 0.00007294 56.0
PYH1_k127_2715160_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.01e-268 839.0
PYH1_k127_2715160_1 reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001001 274.0
PYH1_k127_2715160_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000003379 124.0
PYH1_k127_2715160_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000002648 121.0
PYH1_k127_2715160_4 CP12 domain - - - 0.00000000000000007232 87.0
PYH1_k127_2738905_0 DNA polymerase type-B family K02319 - 2.7.7.7 5.296e-259 823.0
PYH1_k127_2738905_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002829 277.0
PYH1_k127_2738905_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000006313 98.0
PYH1_k127_2762619_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000008362 164.0
PYH1_k127_2762619_1 COG1520 FOG WD40-like repeat - - - 0.000005802 59.0
PYH1_k127_2765457_0 glycoside hydrolase, family - - - 4.336e-274 929.0
PYH1_k127_2765457_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000003163 183.0
PYH1_k127_2765457_2 ASCH - - - 0.000000000000000000000000001424 119.0
PYH1_k127_2765457_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000002237 114.0
PYH1_k127_2765457_4 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0002112 52.0
PYH1_k127_2765457_5 FtsX-like permease family K02004 - - 0.0004131 46.0
PYH1_k127_2790385_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000006996 218.0
PYH1_k127_280690_0 Belongs to the peptidase S8 family - - - 0.000000000000000000002602 109.0
PYH1_k127_2812590_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 459.0
PYH1_k127_2812590_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000008955 263.0
PYH1_k127_2812590_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000006778 201.0
PYH1_k127_2822944_0 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000003058 171.0
PYH1_k127_2823791_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 563.0
PYH1_k127_2823791_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000234 286.0
PYH1_k127_2823791_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000006124 205.0
PYH1_k127_2839927_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 4.234e-282 894.0
PYH1_k127_2839927_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002857 275.0
PYH1_k127_2839927_2 Protein of unknown function (DUF402) K09145 - - 0.000000000000000003941 91.0
PYH1_k127_2849757_0 von willebrand factor, type A K20276 - - 0.0000000000000000000000000000004474 143.0
PYH1_k127_2851566_0 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 354.0
PYH1_k127_2875655_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 562.0
PYH1_k127_2875655_1 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000005069 126.0
PYH1_k127_2877292_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 336.0
PYH1_k127_2877292_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000001759 232.0
PYH1_k127_2877292_2 ABC 3 transport family K09816,K09819 - - 0.00000000000000000000000000000003989 132.0
PYH1_k127_2886937_0 - - - - 0.00000000000000000000000000000000000000000001882 183.0
PYH1_k127_2886937_1 WD-40 repeat - - - 0.0000000000000000000001777 109.0
PYH1_k127_2894268_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 491.0
PYH1_k127_2894268_1 Transglutaminase-like - - - 0.0000000000000792 87.0
PYH1_k127_2913603_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 338.0
PYH1_k127_2913603_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 311.0
PYH1_k127_2913603_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
PYH1_k127_2913603_3 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000001388 127.0
PYH1_k127_2913603_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000006115 79.0
PYH1_k127_291597_0 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 394.0
PYH1_k127_291597_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000005489 276.0
PYH1_k127_291597_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000005013 107.0
PYH1_k127_2919047_0 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.00000000000000000000000000001541 138.0
PYH1_k127_2920070_0 PLD-like domain - - - 0.0008858 53.0
PYH1_k127_2924196_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.555e-201 634.0
PYH1_k127_2924196_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 510.0
PYH1_k127_2924196_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001485 158.0
PYH1_k127_2963906_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
PYH1_k127_2963906_1 Small multi-drug export protein - - - 0.0000000000000000000007776 108.0
PYH1_k127_2967165_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 564.0
PYH1_k127_2967165_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000001835 205.0
PYH1_k127_2967165_2 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000003971 111.0
PYH1_k127_2967165_3 PFAM Rubredoxin - - - 0.0000000000000000000001714 97.0
PYH1_k127_2967165_4 Rubrerythrin - - - 0.0000000000000001641 79.0
PYH1_k127_2968112_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 386.0
PYH1_k127_2968112_1 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 344.0
PYH1_k127_2968112_2 chromatin organization - - - 0.00000000000000000129 93.0
PYH1_k127_2974920_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001838 250.0
PYH1_k127_2974920_1 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000001731 104.0
PYH1_k127_2974920_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000313 94.0
PYH1_k127_2974920_3 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.0000000001295 76.0
PYH1_k127_2975840_0 chlorophyll binding - - - 0.00000000000000000000004674 114.0
PYH1_k127_2975840_1 Protein of unknown function DUF58 - - - 0.00000000000383 78.0
PYH1_k127_2975840_2 COG1305 Transglutaminase-like enzymes K22452 - 2.3.2.13 0.0004255 53.0
PYH1_k127_2980238_0 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
PYH1_k127_2980238_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000001 212.0
PYH1_k127_2996590_0 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.00000000002333 70.0
PYH1_k127_2996590_1 Hep Hag repeat protein K01179 - 3.2.1.4 0.00000004832 67.0
PYH1_k127_2997047_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 453.0
PYH1_k127_2997047_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000001798 209.0
PYH1_k127_2997047_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000000006126 179.0
PYH1_k127_2997047_3 Prenyltransferase and squalene oxidase repeat - - - 0.0000007107 62.0
PYH1_k127_3029798_0 Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - 0.000000000000000000000001008 120.0
PYH1_k127_3030541_0 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 364.0
PYH1_k127_304081_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004066 249.0
PYH1_k127_304081_1 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000001308 178.0
PYH1_k127_3041078_0 ABC transporter K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008267 272.0
PYH1_k127_3041078_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000001257 148.0
PYH1_k127_3041078_2 Transport permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000008979 94.0
PYH1_k127_3051504_0 PKD domain - - - 0.00000000000000000000000000000000000000003185 177.0
PYH1_k127_3051504_1 peptidase activity, acting on L-amino acid peptides K01448,K07260,K09955,K13276 GO:0005575,GO:0005576 3.4.17.14,3.5.1.28 0.000000000000000187 95.0
PYH1_k127_3077415_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000369 239.0
PYH1_k127_3078387_0 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 419.0
PYH1_k127_3078387_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000005855 257.0
PYH1_k127_3112952_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 370.0
PYH1_k127_3112952_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 366.0
PYH1_k127_3112952_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000001209 158.0
PYH1_k127_3120623_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000006656 222.0
PYH1_k127_3121944_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000001644 245.0
PYH1_k127_3121944_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000001038 91.0
PYH1_k127_3124437_0 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 389.0
PYH1_k127_3124437_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 378.0
PYH1_k127_3124437_2 Clostripain family - - - 0.0000000000000000000000000000001609 139.0
PYH1_k127_3124437_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000004079 115.0
PYH1_k127_3124437_4 PFAM regulatory protein, ArsR K21903 - - 0.00000000000000000000000917 116.0
PYH1_k127_3124437_5 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000003473 100.0
PYH1_k127_3124437_6 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000322 69.0
PYH1_k127_3124437_7 - - - - 0.000000001336 62.0
PYH1_k127_3124437_8 cytochrome c biogenesis protein - - - 0.00000001088 68.0
PYH1_k127_3139369_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 427.0
PYH1_k127_3139369_1 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000151 183.0
PYH1_k127_3139369_2 Belongs to the peptidase S8 family - - - 0.0000002619 63.0
PYH1_k127_3140476_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 474.0
PYH1_k127_3140476_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 369.0
PYH1_k127_3140476_2 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.0000000000000000000000000000000000000000000000000000000000000008642 223.0
PYH1_k127_3140476_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000004454 166.0
PYH1_k127_3140476_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000486 149.0
PYH1_k127_3140476_5 Thrombospondin type 3 repeat - - - 0.0000000000000000000000003254 123.0
PYH1_k127_3140476_6 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000001297 110.0
PYH1_k127_3140476_7 Lrp/AsnC ligand binding domain - - - 0.000000000000000004119 87.0
PYH1_k127_3140476_8 PFAM response regulator receiver - - - 0.00000000000001932 78.0
PYH1_k127_3146610_0 YD repeat - - - 0.0000000000000000000005826 113.0
PYH1_k127_3152275_0 PKD domain - - - 0.0000002256 64.0
PYH1_k127_3157859_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 335.0
PYH1_k127_3157859_1 PFAM Major Facilitator Superfamily K19576 - - 0.000000000000000000000000000000000000000000000000000000000293 217.0
PYH1_k127_3157859_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000338 57.0
PYH1_k127_3161803_0 PFAM Type II secretion system protein E K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 590.0
PYH1_k127_3161803_1 type II secretion system protein K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 320.0
PYH1_k127_3161803_2 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000002048 220.0
PYH1_k127_3161803_3 flagella protein K07327,K07328 - - 0.00000000001485 76.0
PYH1_k127_3161803_4 Archaebacterial flagellin K07330 - - 0.0000000003842 66.0
PYH1_k127_3161803_5 archaeal flagellar protein F K07329 - - 0.000000000478 66.0
PYH1_k127_3173248_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 378.0
PYH1_k127_3173248_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000009858 207.0
PYH1_k127_3193469_0 Helix-turn-helix XRE-family like proteins K07728 - - 0.000000000000000000000000000000000000000000000000007156 191.0
PYH1_k127_3193469_1 - - - - 0.0000004218 60.0
PYH1_k127_3212003_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.767e-282 894.0
PYH1_k127_3226495_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 294.0
PYH1_k127_3226495_1 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000008171 149.0
PYH1_k127_3226495_2 - - - - 0.00000000000000000000000000006553 123.0
PYH1_k127_3226495_3 PFAM Ribosomal protein S27E K02978 - - 0.000000000003744 74.0
PYH1_k127_3230988_0 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007505 278.0
PYH1_k127_3230988_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000009638 169.0
PYH1_k127_3230988_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000002855 150.0
PYH1_k127_3230988_3 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000004556 127.0
PYH1_k127_3230988_4 Putative zinc ribbon domain - - - 0.0000000000000002814 84.0
PYH1_k127_3230988_5 alpha/beta hydrolase fold - - - 0.000000003617 63.0
PYH1_k127_3230988_6 - - - - 0.0002481 49.0
PYH1_k127_3242775_0 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009773 241.0
PYH1_k127_3242775_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000004403 132.0
PYH1_k127_3245959_0 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000000000006198 153.0
PYH1_k127_3245959_1 Domain of unknown function - - - 0.0000000000000000000000001391 126.0
PYH1_k127_3245959_2 antibiotic catabolic process - - - 0.0000000000000000000001452 116.0
PYH1_k127_3245959_3 NifU-like domain - - - 0.00000000000034 73.0
PYH1_k127_3245959_4 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000002616 82.0
PYH1_k127_3252271_0 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000001329 164.0
PYH1_k127_3256000_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 3.818e-201 643.0
PYH1_k127_3256000_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 398.0
PYH1_k127_3256000_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000005937 204.0
PYH1_k127_3256000_3 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000008656 187.0
PYH1_k127_3256000_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000002791 82.0
PYH1_k127_3256000_5 Rubrerythrin - - - 0.00000008619 54.0
PYH1_k127_326135_0 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000001126 149.0
PYH1_k127_326135_1 protein conserved in archaea K09746 - - 0.000001069 53.0
PYH1_k127_3268282_0 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008856 283.0
PYH1_k127_3268282_1 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000007371 191.0
PYH1_k127_3278898_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000001439 155.0
PYH1_k127_3278898_1 lyase activity - - - 0.000000002048 66.0
PYH1_k127_3287483_0 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 389.0
PYH1_k127_3287483_1 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 - - 0.00000000000000000000000000000000000000000000000000000009839 203.0
PYH1_k127_3287483_2 AAA domain, putative AbiEii toxin, Type IV TA system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000001512 203.0
PYH1_k127_3287483_3 CcmB protein K02194 - - 0.00000000000000000000000000007752 127.0
PYH1_k127_3287483_4 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000009229 109.0
PYH1_k127_3296394_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
PYH1_k127_3311302_0 AIG2-like family - - - 0.00000000005694 68.0
PYH1_k127_333899_0 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000002544 61.0
PYH1_k127_3357388_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000002562 209.0
PYH1_k127_3357388_1 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001298 164.0
PYH1_k127_3357388_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000000001202 121.0
PYH1_k127_3362193_0 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000001842 139.0
PYH1_k127_3362193_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000002608 133.0
PYH1_k127_3362193_2 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000002458 54.0
PYH1_k127_3362853_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002191 252.0
PYH1_k127_3362853_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002423 265.0
PYH1_k127_3362853_2 Ion channel K10716 - - 0.0000000000000000004654 100.0
PYH1_k127_3372814_0 Serine protease with a broad substrate specificity K13276,K17734 - - 0.000000000000000000000000001947 130.0
PYH1_k127_3372814_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000372 106.0
PYH1_k127_3372814_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01083,K06131,K06915 - 3.1.3.8 0.0000006748 63.0
PYH1_k127_3387157_0 Protein conserved in bacteria K20276 - - 0.000000003815 70.0
PYH1_k127_3413744_0 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 406.0
PYH1_k127_3413744_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 385.0
PYH1_k127_3413744_2 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000000000000000214 215.0
PYH1_k127_3413744_3 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000005159 183.0
PYH1_k127_3413744_4 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000004999 108.0
PYH1_k127_3413744_5 TIGRFAM Outer membrane protein K13735,K20276 - - 0.00000000000007475 86.0
PYH1_k127_3421530_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000002152 123.0
PYH1_k127_3421530_1 PFAM Prenyltransferase squalene oxidase - - - 0.0000002311 66.0
PYH1_k127_3458544_0 ATPases associated with a variety of cellular activities K02074 - - 0.00000000000000000000000000000000000000000000000000001309 198.0
PYH1_k127_3458544_1 formylmethanofuran dehydrogenase, subunit E - - - 0.0000000000000000001232 99.0
PYH1_k127_3458544_2 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000613 66.0
PYH1_k127_3458544_3 ABC 3 transport family K02075 - - 0.0001742 47.0
PYH1_k127_3463918_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 367.0
PYH1_k127_3463918_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000003988 152.0
PYH1_k127_3463918_2 ABC transporter K02049 - - 0.0000000000000000000008823 96.0
PYH1_k127_3486162_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000613 147.0
PYH1_k127_3511602_0 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002699 246.0
PYH1_k127_3511602_1 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0000007187 64.0
PYH1_k127_3515389_0 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002377 169.0
PYH1_k127_3515389_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002669 147.0
PYH1_k127_3515389_2 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004217 132.0
PYH1_k127_3515389_3 dna-directed rna K03007 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005666,GO:0005730,GO:0005736,GO:0006139,GO:0006351,GO:0006360,GO:0006366,GO:0006383,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009304,GO:0009987,GO:0010467,GO:0016070,GO:0016591,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0042797,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097659,GO:0098781,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - 0.00000000000000000002414 94.0
PYH1_k127_3521443_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 419.0
PYH1_k127_3529563_0 CARDB - - - 0.0007632 52.0
PYH1_k127_3540939_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1537.0
PYH1_k127_3540939_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1191.0
PYH1_k127_3540939_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000245 85.0
PYH1_k127_3542321_0 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003129 261.0
PYH1_k127_3542321_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
PYH1_k127_3560110_0 Cytochrome c3 - - - 0.0000001101 64.0
PYH1_k127_3567357_0 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000004812 186.0
PYH1_k127_3567357_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000002107 147.0
PYH1_k127_3567357_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000002823 52.0
PYH1_k127_3575810_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 310.0
PYH1_k127_3575810_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.0000000000000003634 82.0
PYH1_k127_3587736_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008845 246.0
PYH1_k127_3587736_1 von Willebrand factor, type A K11912 - 2.7.11.1 0.000000000000000000000000000000008504 139.0
PYH1_k127_3587736_2 Protein of unknown function (DUF1722) - - - 0.000000001003 61.0
PYH1_k127_3590282_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
PYH1_k127_3590282_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000005352 142.0
PYH1_k127_3590282_2 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000007316 139.0
PYH1_k127_3590282_3 Flavodoxin - - - 0.000000000000000000000000000007418 129.0
PYH1_k127_3590282_4 transcriptional - - - 0.000000009308 67.0
PYH1_k127_361280_0 PFAM Fibronectin type III domain - - - 0.000000003707 69.0
PYH1_k127_3624121_0 SMART Tetratricopeptide - - - 0.000002257 59.0
PYH1_k127_3624121_1 - - - - 0.00000306 59.0
PYH1_k127_3642804_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 626.0
PYH1_k127_3642804_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008546 285.0
PYH1_k127_3642804_10 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001168 140.0
PYH1_k127_3642804_11 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004225 142.0
PYH1_k127_3642804_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001638 115.0
PYH1_k127_3642804_13 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002201 112.0
PYH1_k127_3642804_14 Binds to the 23S rRNA K02876 - - 0.000000000000000000005536 98.0
PYH1_k127_3642804_15 ribosomal protein S14 K02954 - - 0.00000000000000005354 89.0
PYH1_k127_3642804_16 Ribosomal L29 protein K02904 - - 0.00000000004067 64.0
PYH1_k127_3642804_17 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000001171 66.0
PYH1_k127_3642804_2 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
PYH1_k127_3642804_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000006427 210.0
PYH1_k127_3642804_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000002954 209.0
PYH1_k127_3642804_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000002415 184.0
PYH1_k127_3642804_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000004377 181.0
PYH1_k127_3642804_7 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000007608 174.0
PYH1_k127_3642804_8 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000933 168.0
PYH1_k127_3642804_9 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000726 164.0
PYH1_k127_3647742_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000006124 236.0
PYH1_k127_3647742_1 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000001513 151.0
PYH1_k127_3647742_2 Efflux ABC transporter, permease protein K02004 - - 0.0000000000002091 82.0
PYH1_k127_3647742_3 Fungalysin metallopeptidase (M36) - - - 0.0008264 52.0
PYH1_k127_3650578_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 462.0
PYH1_k127_3650578_1 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0009318 47.0
PYH1_k127_3655760_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 492.0
PYH1_k127_3655760_1 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.000000000000000000000003245 108.0
PYH1_k127_379482_0 6-phosphogluconolactonase activity - - - 0.0000000000000000001407 105.0
PYH1_k127_3841994_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 319.0
PYH1_k127_3841994_1 COG1361 S-layer domain - - - 0.000000000000000000000000000000000007606 153.0
PYH1_k127_3841994_2 Roadblock LC7 family protein K07131 - - 0.00000000000741 74.0
PYH1_k127_3841994_3 TIGRFAM geranylgeranyl reductase - - - 0.0000008843 53.0
PYH1_k127_3847725_0 COG3291 FOG PKD repeat - - - 0.0000000000000000000000000000000000000000000000007933 199.0
PYH1_k127_3847725_1 Double zinc ribbon - - - 0.000003583 49.0
PYH1_k127_3877613_0 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000006361 152.0
PYH1_k127_3877613_1 Calcineurin-like phosphoesterase superfamily domain K01090 - 3.1.3.16 0.00000000000000000000000298 108.0
PYH1_k127_3877613_2 metal-sulfur cluster biosynthetic enzyme K02612,K04488 - - 0.00000000000000002294 89.0
PYH1_k127_3877613_3 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.0000000000005654 78.0
PYH1_k127_3914371_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002038 245.0
PYH1_k127_3914371_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000001827 216.0
PYH1_k127_3914371_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000004518 160.0
PYH1_k127_3914371_3 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000009952 87.0
PYH1_k127_3914371_4 mttA/Hcf106 family K03116 - - 0.0000000001139 69.0
PYH1_k127_3917434_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.252e-271 852.0
PYH1_k127_3920816_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000009697 130.0
PYH1_k127_3928482_0 Belongs to the complex I 49 kDa subunit family K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 372.0
PYH1_k127_3928482_1 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
PYH1_k127_3928482_10 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000001898 110.0
PYH1_k127_3928482_11 toxin-antitoxin pair type II binding - - - 0.00000000000000000000001812 102.0
PYH1_k127_3928482_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.000000000000000000002069 105.0
PYH1_k127_3928482_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000001704 102.0
PYH1_k127_3928482_14 Glyoxalase-like domain K06996 - - 0.0000000000000000007465 92.0
PYH1_k127_3928482_15 - - - - 0.0000000000002487 80.0
PYH1_k127_3928482_16 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000374 53.0
PYH1_k127_3928482_2 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 305.0
PYH1_k127_3928482_3 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 292.0
PYH1_k127_3928482_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001642 271.0
PYH1_k127_3928482_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007207 263.0
PYH1_k127_3928482_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
PYH1_k127_3928482_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 255.0
PYH1_k127_3928482_8 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000001004 190.0
PYH1_k127_3928482_9 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000001439 198.0
PYH1_k127_3950521_0 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 494.0
PYH1_k127_3950521_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000002242 82.0
PYH1_k127_3967639_0 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006105 252.0
PYH1_k127_3967639_1 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000000002897 179.0
PYH1_k127_3967639_2 Mut7-C RNAse domain K09122 - - 0.00000000001644 67.0
PYH1_k127_3976948_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002863 253.0
PYH1_k127_3976948_1 Fibronectin type III domain protein - - - 0.0000000000000000000000000000000000000909 164.0
PYH1_k127_3995857_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 356.0
PYH1_k127_3995857_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000003574 176.0
PYH1_k127_3995857_2 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000007027 158.0
PYH1_k127_3995857_3 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000002358 126.0
PYH1_k127_4023254_0 diguanylate cyclase - - - 0.000000000002589 79.0
PYH1_k127_4071882_0 Belongs to the terpene synthase family K04120,K14043 GO:0000287,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006720,GO:0006721,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009536,GO:0009685,GO:0009686,GO:0009719,GO:0009725,GO:0009739,GO:0009740,GO:0009755,GO:0009905,GO:0009987,GO:0010033,GO:0010476,GO:0010817,GO:0016053,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019752,GO:0023052,GO:0032870,GO:0033993,GO:0042221,GO:0042445,GO:0042446,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071229,GO:0071310,GO:0071370,GO:0071396,GO:0071495,GO:0071704,GO:1901576,GO:1901700,GO:1901701 5.5.1.13,5.5.1.14 0.000000000000000000000000000000000000005964 164.0
PYH1_k127_4088390_0 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000006868 188.0
PYH1_k127_4088390_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000001723 189.0
PYH1_k127_4088390_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000007351 173.0
PYH1_k127_4088390_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000001521 85.0
PYH1_k127_4089182_0 domain, Protein - - - 0.0000000000000000001305 105.0
PYH1_k127_4089182_1 Glycosyl hydrolase family 81 - - - 0.0008972 53.0
PYH1_k127_4117106_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001917 61.0
PYH1_k127_4123600_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 525.0
PYH1_k127_4123600_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 522.0
PYH1_k127_4123600_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 305.0
PYH1_k127_4123600_3 - K07092 - - 0.000000000000000000000000000000000000000000000000003724 183.0
PYH1_k127_4123600_4 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000000000000000002342 119.0
PYH1_k127_4123600_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000003332 68.0
PYH1_k127_4135098_0 archaeal Zn-finger protein - - - 0.000000000000000000000000000785 123.0
PYH1_k127_4135098_1 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753,K13818 - 2.7.7.77 0.00000000000000003571 89.0
PYH1_k127_4145206_0 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 474.0
PYH1_k127_4145206_1 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000001245 219.0
PYH1_k127_4145206_2 Fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000007387 94.0
PYH1_k127_4152251_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 585.0
PYH1_k127_4152251_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 479.0
PYH1_k127_4152251_10 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000001977 120.0
PYH1_k127_4152251_11 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.00000000000009344 72.0
PYH1_k127_4152251_12 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000001472 72.0
PYH1_k127_4152251_13 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000001053 68.0
PYH1_k127_4152251_14 Major facilitator superfamily - - - 0.00007329 54.0
PYH1_k127_4152251_2 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 439.0
PYH1_k127_4152251_3 acetylornithine and succinylornithine aminotransferase K00821,K05830 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 399.0
PYH1_k127_4152251_4 PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 347.0
PYH1_k127_4152251_5 ferredoxin oxidoreductase, subunit beta K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 324.0
PYH1_k127_4152251_6 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
PYH1_k127_4152251_7 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001745 256.0
PYH1_k127_4152251_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000001892 191.0
PYH1_k127_4152251_9 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000004149 141.0
PYH1_k127_4228936_0 PFAM Polysaccharide deacetylase - - - 0.00000000000001859 88.0
PYH1_k127_4228936_1 WD-40 repeat - - - 0.0000000001816 68.0
PYH1_k127_4228936_2 Phage integrase family K06930 - - 0.0005405 52.0
PYH1_k127_4241605_0 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 398.0
PYH1_k127_425617_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001171 268.0
PYH1_k127_425617_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000001672 166.0
PYH1_k127_425617_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000005216 78.0
PYH1_k127_4257221_0 domain protein K01179,K01342,K01406,K07004,K12287,K14194,K15125,K20276 - 3.2.1.4,3.4.21.62,3.4.24.40 0.0000000000009811 82.0
PYH1_k127_4266988_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000001974 140.0
PYH1_k127_4266988_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000005808 96.0
PYH1_k127_4266988_2 chlorophyll binding - - - 0.0000000001756 75.0
PYH1_k127_4280207_0 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000007514 235.0
PYH1_k127_4280207_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000002117 220.0
PYH1_k127_4280207_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000006002 181.0
PYH1_k127_4280207_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000004979 158.0
PYH1_k127_4319125_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.946e-283 888.0
PYH1_k127_4319125_1 Fibronectin type 3 domain - - - 0.000000000000005328 89.0
PYH1_k127_4319125_2 transglutaminase domain protein - - - 0.0001879 54.0
PYH1_k127_4319125_3 - - - - 0.000346 52.0
PYH1_k127_4328395_0 glycoside hydrolase, family - - - 0.00000000000000000000000000000000001161 153.0
PYH1_k127_4328395_1 Hypothetical methyltransferase - - - 0.0001796 50.0
PYH1_k127_4336085_0 methanogenesis marker protein 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001197 295.0
PYH1_k127_4336085_1 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002711 248.0
PYH1_k127_4336085_2 TrkA-C domain protein K07228 - - 0.00000000000000000000000000088 118.0
PYH1_k127_4336085_3 Kef-type K transport K03455 - - 0.0000000000000000000412 101.0
PYH1_k127_4400123_0 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
PYH1_k127_4400123_1 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000001052 181.0
PYH1_k127_4400123_2 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000001611 136.0
PYH1_k127_4413410_0 MCM OB domain K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 346.0
PYH1_k127_4446148_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000006944 59.0
PYH1_k127_4452225_0 CAAX protease self-immunity K07052 - - 0.000000000000000004987 95.0
PYH1_k127_4452225_1 - - - - 0.000000003359 66.0
PYH1_k127_4477210_0 cog cog1373 K07133 - - 0.00000000000000000000000000000000000000000001479 179.0
PYH1_k127_4477210_1 Pterin binding enzyme K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.00000000000000000002389 92.0
PYH1_k127_448763_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH1_k127_448763_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001304 246.0
PYH1_k127_448763_2 deoxyhypusine monooxygenase activity - - - 0.00000003393 57.0
PYH1_k127_4490797_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007436 285.0
PYH1_k127_4490797_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001074 220.0
PYH1_k127_4490797_2 nucleotidyltransferase activity K07076 - - 0.00000000000000000001772 99.0
PYH1_k127_4490797_3 HEPN domain K09132 - - 0.00000001401 64.0
PYH1_k127_4505030_0 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 300.0
PYH1_k127_4505030_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000005387 84.0
PYH1_k127_4517323_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000004763 59.0
PYH1_k127_4557799_0 Ethylbenzene dehydrogenase - - - 0.0000000000000000001988 103.0
PYH1_k127_4577572_0 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000001287 158.0
PYH1_k127_4577572_1 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000006707 153.0
PYH1_k127_4577572_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000001907 113.0
PYH1_k127_4577572_3 PFAM NHL repeat containing protein - - - 0.0000000000000000003831 103.0
PYH1_k127_4577572_4 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652,K13653 - - 0.00000000000131 75.0
PYH1_k127_4577572_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000004265 77.0
PYH1_k127_4577572_6 DNA binding protein - - - 0.00000005752 61.0
PYH1_k127_4577572_7 YoaP-like - - - 0.000592 52.0
PYH1_k127_4589800_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 353.0
PYH1_k127_4589800_1 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000006045 272.0
PYH1_k127_4589800_2 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000005016 196.0
PYH1_k127_4589800_3 - - - - 0.0000000000000000000000002958 108.0
PYH1_k127_4589800_4 Lrp/AsnC ligand binding domain - - - 0.0000000000000000001274 95.0
PYH1_k127_4589800_5 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000009097 85.0
PYH1_k127_4589800_6 - - - - 0.000000000004629 68.0
PYH1_k127_4598397_0 - - - - 0.000000000000000000000000000000000006464 144.0
PYH1_k127_4598397_1 Protein of unknown function (DUF2683) - - - 0.000003812 51.0
PYH1_k127_4598397_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0001337 53.0
PYH1_k127_4601082_0 WD40-like Beta Propeller Repeat K03641 - - 0.000000000001491 80.0
PYH1_k127_4609931_0 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000000000001051 239.0
PYH1_k127_4609931_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000914 203.0
PYH1_k127_4609931_2 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000008635 58.0
PYH1_k127_4615311_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 612.0
PYH1_k127_4615311_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 349.0
PYH1_k127_4615311_2 - - - - 0.0000000000002336 75.0
PYH1_k127_4615311_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000007392 66.0
PYH1_k127_4615311_4 Bacterial PH domain - - - 0.00001485 55.0
PYH1_k127_4620880_0 Right handed beta helix region - - - 0.0002084 52.0
PYH1_k127_4624161_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 469.0
PYH1_k127_4624161_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000003223 252.0
PYH1_k127_4624161_2 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
PYH1_k127_4624161_3 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000007495 181.0
PYH1_k127_4624161_4 Permeases of the drug metabolite transporter (DMT) superfamily K03298 - - 0.00000000000006248 82.0
PYH1_k127_4638736_0 glycoside hydrolase, family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 412.0
PYH1_k127_4643945_0 Extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000004122 232.0
PYH1_k127_4643945_1 sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000001107 179.0
PYH1_k127_4643945_2 ABC-type spermidine putrescine transport systems, ATPase components K02010 - 3.6.3.30 0.0000000000000000000005676 98.0
PYH1_k127_4643945_3 SpoVT / AbrB like domain - - - 0.0001764 46.0
PYH1_k127_4652269_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 416.0
PYH1_k127_4652269_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 322.0
PYH1_k127_4652269_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000002855 218.0
PYH1_k127_4652269_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000006845 203.0
PYH1_k127_4652269_4 myosin light chain kinase activity K12567 - 2.7.11.1 0.000000000000000000000000000000003034 151.0
PYH1_k127_4653175_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 464.0
PYH1_k127_4653175_1 - - - - 0.00000000000001848 79.0
PYH1_k127_4653175_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000258 80.0
PYH1_k127_4659135_0 domain protein - - - 0.000003027 60.0
PYH1_k127_4663446_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 2.687e-201 637.0
PYH1_k127_4663446_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 329.0
PYH1_k127_4663446_2 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000009901 235.0
PYH1_k127_4663446_3 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000002971 224.0
PYH1_k127_4663446_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000000000000000000000006773 184.0
PYH1_k127_4663446_5 PFAM ribosomal protein S8E K02995 - - 0.000000000000000000000000000000003694 132.0
PYH1_k127_4663446_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000000002167 85.0
PYH1_k127_4663446_7 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000386 78.0
PYH1_k127_4663721_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000003781 194.0
PYH1_k127_4663721_1 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000009077 176.0
PYH1_k127_4663721_2 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000005866 102.0
PYH1_k127_4663721_3 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002219 91.0
PYH1_k127_4663721_4 May be involved in the transport of PQQ or its precursor to the periplasm K06136,K06167 - 3.1.4.55 0.00000000000227 70.0
PYH1_k127_4663721_5 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000000003484 67.0
PYH1_k127_4681528_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000004952 239.0
PYH1_k127_4681528_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000009599 143.0
PYH1_k127_4681528_2 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000009745 123.0
PYH1_k127_4703355_0 - - - - 0.00000000000000000000000000000002963 136.0
PYH1_k127_4726705_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000002085 259.0
PYH1_k127_4726705_1 amine dehydrogenase activity K20276,K21430 - - 0.000000000000000000553 104.0
PYH1_k127_4728455_0 Papain family cysteine protease - - - 0.0000000000000000007137 102.0
PYH1_k127_4765186_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000007568 238.0
PYH1_k127_4781811_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 9.766e-217 679.0
PYH1_k127_4781811_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 526.0
PYH1_k127_4781811_10 Putative transposon-encoded protein (DUF2080) - - - 0.0000000000000002395 79.0
PYH1_k127_4781811_11 Molybdopterin oxidoreductase Fe4S4 domain K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000004243 68.0
PYH1_k127_4781811_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 452.0
PYH1_k127_4781811_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 336.0
PYH1_k127_4781811_4 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 325.0
PYH1_k127_4781811_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
PYH1_k127_4781811_6 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 261.0
PYH1_k127_4781811_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000002846 140.0
PYH1_k127_4781811_8 4 iron, 4 sulfur cluster binding K00205,K02573 - - 0.0000000000000000000000001097 109.0
PYH1_k127_4781811_9 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00176 - 1.2.7.3 0.000000000000000003852 86.0
PYH1_k127_4782659_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 318.0
PYH1_k127_4794608_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 405.0
PYH1_k127_4794608_1 COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit K07398 - - 0.00000000000001273 76.0
PYH1_k127_4801031_0 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000005349 162.0
PYH1_k127_4801031_1 Methyltransferase - - - 0.0000000000000000003175 95.0
PYH1_k127_4801081_0 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000000003076 139.0
PYH1_k127_4801317_0 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000001348 126.0
PYH1_k127_4803070_0 Dodecin K09165 - - 0.000000000000006703 78.0
PYH1_k127_4803070_1 - - - - 0.000001193 59.0
PYH1_k127_4803070_2 - - - - 0.000002251 55.0
PYH1_k127_4803577_0 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000285 160.0
PYH1_k127_4803577_1 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000006234 90.0
PYH1_k127_4803577_2 - - - - 0.00000000000000197 80.0
PYH1_k127_4803577_3 Tetratricopeptide repeat - - - 0.000003566 55.0
PYH1_k127_4806455_0 COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001929 266.0
PYH1_k127_4820314_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000007921 133.0
PYH1_k127_4821193_0 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000009085 156.0
PYH1_k127_4821193_1 S-layer homology domain - - - 0.00000000000000000000000000000000006473 156.0
PYH1_k127_4821193_2 Zc3h12a-like Ribonuclease NYN domain - - - 0.000000000003044 74.0
PYH1_k127_4821193_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000003712 77.0
PYH1_k127_4836533_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 360.0
PYH1_k127_4836533_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 323.0
PYH1_k127_4836533_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000002963 92.0
PYH1_k127_4840377_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000003759 216.0
PYH1_k127_4840377_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000001579 132.0
PYH1_k127_4874608_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 397.0
PYH1_k127_4874608_1 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000008469 233.0
PYH1_k127_4874608_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000003321 136.0
PYH1_k127_4874608_3 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001628 118.0
PYH1_k127_4874608_4 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000115 82.0
PYH1_k127_4874608_5 von willebrand factor, type A K20276 - - 0.0000000004055 74.0
PYH1_k127_4877017_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001644 291.0
PYH1_k127_4936838_0 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000006358 189.0
PYH1_k127_4936838_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000001169 116.0
PYH1_k127_4936838_2 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000512 79.0
PYH1_k127_4936838_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000184 59.0
PYH1_k127_4947555_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000107 62.0
PYH1_k127_4958663_0 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
PYH1_k127_4958663_1 binds to the 23S rRNA K02921 - - 0.00000000000000002087 85.0
PYH1_k127_4958663_2 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000001026 57.0
PYH1_k127_4966218_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001517 288.0
PYH1_k127_4966218_1 Clan AA aspartic protease - - - 0.00007396 53.0
PYH1_k127_4971146_0 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000001967 175.0
PYH1_k127_4983092_0 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 381.0
PYH1_k127_4983092_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 341.0
PYH1_k127_4983092_2 Peptidase inhibitor I9 K17734 - - 0.0000000000000000000000000000000001272 151.0
PYH1_k127_4983092_3 cheY-homologous receiver domain K03413 - - 0.00000000000000002311 93.0
PYH1_k127_4983092_4 transcriptional - - - 0.000001241 60.0
PYH1_k127_4983092_5 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0002146 51.0
PYH1_k127_4988350_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 306.0
PYH1_k127_4988350_1 epimerase - - - 0.00000000000000000000000000000000000000000000000000000009479 204.0
PYH1_k127_4988350_2 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000001912 93.0
PYH1_k127_5008464_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 297.0
PYH1_k127_5044310_0 Fibronectin type III domain K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000002184 259.0
PYH1_k127_5044310_1 Beta-propeller repeat - - - 0.00000000000000000000000706 119.0
PYH1_k127_5081578_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000001545 197.0
PYH1_k127_5081578_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K17870 - 1.6.3.3 0.00000000000000000000000000005874 123.0
PYH1_k127_5084032_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 452.0
PYH1_k127_5084032_1 Fe-S cluster K04488 - - 0.0000000000000000000000000000000000000000000000000001693 190.0
PYH1_k127_5084032_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000003169 117.0
PYH1_k127_5084032_3 - - - - 0.000000000000001225 82.0
PYH1_k127_5084032_4 von willebrand factor, type A K12549 - - 0.0000000000008253 83.0
PYH1_k127_5084032_5 Oxidoreductase molybdopterin binding domain K00387 - 1.8.3.1 0.000246 54.0
PYH1_k127_5084411_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000002645 214.0
PYH1_k127_5084411_1 PKD domain - - - 0.00002761 56.0
PYH1_k127_5086200_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005307 288.0
PYH1_k127_5096570_0 TraB family - - - 0.000000000000000000000000000002194 130.0
PYH1_k127_5096570_1 domain, Protein - - - 0.00000007376 56.0
PYH1_k127_5110686_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 285.0
PYH1_k127_5110686_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000008373 187.0
PYH1_k127_513350_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000004356 192.0
PYH1_k127_513350_1 translation initiation factor activity K03680 - - 0.000000000000003387 86.0
PYH1_k127_5156996_0 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 333.0
PYH1_k127_5156996_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000001757 185.0
PYH1_k127_5156996_2 Transcriptional regulator - - - 0.000000000000000000000005039 109.0
PYH1_k127_5161125_0 Carboxypeptidase regulatory-like domain - - - 0.0000004404 63.0
PYH1_k127_5161125_1 phosphoesterase, PA-phosphatase related - - - 0.000007896 51.0
PYH1_k127_5171810_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 312.0
PYH1_k127_5171810_1 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000102 220.0
PYH1_k127_5171810_2 DRTGG domain protein K06873 - - 0.0000003954 53.0
PYH1_k127_5182487_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 331.0
PYH1_k127_5182487_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007161 283.0
PYH1_k127_5182487_2 Protein conserved in bacteria K07192 - - 0.000000000000000000000000000000000000000000000000000000000000002574 237.0
PYH1_k127_5182487_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00001189 55.0
PYH1_k127_5206257_0 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000001014 110.0
PYH1_k127_5206257_1 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.0001291 57.0
PYH1_k127_5270511_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 296.0
PYH1_k127_5270511_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 267.0
PYH1_k127_5270511_2 - - - - 0.00000000000000000000000000000000000000000000000000000008188 215.0
PYH1_k127_5275124_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 489.0
PYH1_k127_5275124_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 296.0
PYH1_k127_5292815_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000005685 158.0
PYH1_k127_5292815_1 COG3291 FOG PKD repeat K01387 GO:0005575,GO:0005576 3.4.24.3 0.000000000000000000002071 108.0
PYH1_k127_5292815_2 isoprenylcysteine carboxyl methyltransferase - - - 0.000000004574 68.0
PYH1_k127_5299182_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000002853 236.0
PYH1_k127_5299182_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000614 213.0
PYH1_k127_5299182_2 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000001268 176.0
PYH1_k127_5299182_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000008855 140.0
PYH1_k127_5304533_0 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.0000000000000000000000000002465 129.0
PYH1_k127_5323680_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 355.0
PYH1_k127_5323680_1 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 274.0
PYH1_k127_5323680_2 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000001233 227.0
PYH1_k127_5323680_3 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000005613 102.0
PYH1_k127_5323680_4 homophilic cell adhesion via plasma membrane adhesion molecules K02599,K08115,K16507,K16669,K19013 GO:0000187,GO:0000323,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005775,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0005912,GO:0005924,GO:0005927,GO:0006022,GO:0006023,GO:0006024,GO:0006026,GO:0006027,GO:0006029,GO:0006082,GO:0006790,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007186,GO:0007275,GO:0007399,GO:0007517,GO:0008150,GO:0008152,GO:0008283,GO:0008347,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009653,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010721,GO:0010927,GO:0010975,GO:0010977,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016053,GO:0016203,GO:0016322,GO:0016477,GO:0017144,GO:0019220,GO:0019222,GO:0019538,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030054,GO:0030055,GO:0030154,GO:0030166,GO:0030182,GO:0030203,GO:0030204,GO:0030205,GO:0030206,GO:0030207,GO:0030208,GO:0030239,GO:0031032,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031346,GO:0031399,GO:0031401,GO:0031674,GO:0031974,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032787,GO:0032989,GO:0033674,GO:0034645,GO:0035556,GO:0040011,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042551,GO:0042692,GO:0042995,GO:0043034,GO:0043085,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043436,GO:0043549,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044272,GO:0044273,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044464,GO:0044877,GO:0045214,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045859,GO:0045860,GO:0045937,GO:0046394,GO:0048468,GO:0048469,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050650,GO:0050651,GO:0050654,GO:0050655,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051286,GO:0051338,GO:0051347,GO:0051489,GO:0051491,GO:0051674,GO:0051716,GO:0051960,GO:0051961,GO:0055001,GO:0055002,GO:0060255,GO:0060284,GO:0060491,GO:0060538,GO:0061061,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070925,GO:0071695,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072330,GO:0080090,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0120032,GO:0120034,GO:0120035,GO:1901135,GO:1901136,GO:1901137,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902531,GO:1902533,GO:1903510,GO:2000026 - 0.00000000000000000004554 107.0
PYH1_k127_5323680_5 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000001008 91.0
PYH1_k127_5323680_6 domain protein - - - 0.000000000000002206 92.0
PYH1_k127_5323680_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000005502 68.0
PYH1_k127_5323680_8 Transcriptional regulator, TrmB - - - 0.00000001237 66.0
PYH1_k127_5323680_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000005088 64.0
PYH1_k127_5336816_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 542.0
PYH1_k127_5336816_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000002268 132.0
PYH1_k127_5341889_0 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 404.0
PYH1_k127_5341889_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002002 281.0
PYH1_k127_5341889_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000001356 251.0
PYH1_k127_5341889_3 Glycosyl transferase 4-like - - - 0.000000000000000002037 96.0
PYH1_k127_5341889_4 poly-hydroxybutyrate biosynthetic process - - - 0.0000007966 61.0
PYH1_k127_5368344_0 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 409.0
PYH1_k127_5371946_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000002355 226.0
PYH1_k127_5371946_1 - - - - 0.000007295 55.0
PYH1_k127_5432879_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 3.147e-263 839.0
PYH1_k127_5436530_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 7.172e-194 629.0
PYH1_k127_5436530_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000002249 98.0
PYH1_k127_5436530_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000001464 85.0
PYH1_k127_5436530_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000248 71.0
PYH1_k127_5436530_4 lipase activity K15125 - - 0.00000002127 68.0
PYH1_k127_5465673_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 538.0
PYH1_k127_5465673_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000003442 192.0
PYH1_k127_5465673_2 Redoxin K03564 - 1.11.1.15 0.0000001229 53.0
PYH1_k127_5473192_0 Peptidase family C25 - - - 0.0000000000000000000000000000003143 144.0
PYH1_k127_5473192_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000005508 89.0
PYH1_k127_5473192_2 Rhs Family - - - 0.000000608 64.0
PYH1_k127_5476078_0 RHS Repeat - - - 0.000000000000000007421 100.0
PYH1_k127_5476078_1 Belongs to the glycosyl hydrolase family 6 - - - 0.0000000000282 78.0
PYH1_k127_5476078_2 Kelch domain containing 4 - - - 0.0000000005831 74.0
PYH1_k127_5477106_0 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000014 93.0
PYH1_k127_5481573_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 1.045e-223 705.0
PYH1_k127_5481573_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
PYH1_k127_5481573_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000155 238.0
PYH1_k127_5481573_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000003452 201.0
PYH1_k127_5481573_4 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00001091 48.0
PYH1_k127_5481573_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00002196 47.0
PYH1_k127_5488904_0 TCP-1/cpn60 chaperonin family K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 600.0
PYH1_k127_5488904_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.0000000000000000000000002176 106.0
PYH1_k127_5488904_2 transcriptional - - - 0.0000000000000000000004091 105.0
PYH1_k127_5488904_3 RNase_H superfamily K07502 - - 0.0000000000005019 72.0
PYH1_k127_5495373_0 Ethylbenzene dehydrogenase - - - 0.000000000000000001308 102.0
PYH1_k127_5495373_1 Carboxypeptidase regulatory-like domain - - - 0.000000003047 70.0
PYH1_k127_5495373_2 Pyrrolo-quinoline quinone - - - 0.000000009175 68.0
PYH1_k127_5513274_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000004513 173.0
PYH1_k127_5513274_1 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000004646 133.0
PYH1_k127_5513274_2 6-phosphogluconolactonase activity K01991,K20987 - - 0.000000000000000002796 101.0
PYH1_k127_5513947_0 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000004484 186.0
PYH1_k127_5513947_1 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000002815 150.0
PYH1_k127_5525167_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 351.0
PYH1_k127_5525167_1 Large-conductance mechanosensitive channel, MscL K03282 - - 0.00000000000000001667 87.0
PYH1_k127_5525167_2 PFAM nucleic acid binding OB-fold tRNA helicase-type - - - 0.000002818 61.0
PYH1_k127_5533212_0 CARDB - - - 0.000001887 62.0
PYH1_k127_5613665_0 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 354.0
PYH1_k127_5613665_1 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 293.0
PYH1_k127_5613665_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004422 284.0
PYH1_k127_5613665_3 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000001314 147.0
PYH1_k127_5613665_4 RNA-binding - - - 0.000000000000000000000000001051 115.0
PYH1_k127_5631153_0 COGs COG3367 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008668 256.0
PYH1_k127_5631153_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000004722 204.0
PYH1_k127_5631153_2 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000001145 149.0
PYH1_k127_5634301_0 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 482.0
PYH1_k127_5634301_1 OsmC-like protein - - - 0.000000000000000000000002411 111.0
PYH1_k127_5634301_2 Uncharacterized protein family UPF0016 - - - 0.0000000000000000001739 99.0
PYH1_k127_5634301_5 Highly conserved protein containing a thioredoxin domain - - - 0.00006905 55.0
PYH1_k127_5634301_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0001282 46.0
PYH1_k127_5644956_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000007069 199.0
PYH1_k127_5644956_1 It is involved in the biological process described with protein phosphorylation K12567 GO:0003008,GO:0003012,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005859,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006996,GO:0007010,GO:0007015,GO:0007498,GO:0007610,GO:0007626,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0008344,GO:0009636,GO:0009653,GO:0009888,GO:0009987,GO:0010638,GO:0010720,GO:0010927,GO:0015629,GO:0016043,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022603,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030534,GO:0031032,GO:0031033,GO:0031034,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033043,GO:0034622,GO:0035094,GO:0035095,GO:0036211,GO:0040012,GO:0040017,GO:0042221,GO:0042493,GO:0042692,GO:0042805,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0043933,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045214,GO:0045595,GO:0045597,GO:0045933,GO:0045989,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051015,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051239,GO:0051240,GO:0051302,GO:0051371,GO:0051393,GO:0051493,GO:0051495,GO:0051782,GO:0055001,GO:0055002,GO:0060284,GO:0060297,GO:0060298,GO:0061061,GO:0065003,GO:0065007,GO:0070925,GO:0071688,GO:0071689,GO:0071704,GO:0071840,GO:0090257,GO:0097435,GO:0097493,GO:0099080,GO:0099081,GO:0099512,GO:0110020,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1902903,GO:1902905 2.7.11.1 0.0001619 49.0
PYH1_k127_5646209_0 OmpA family - - - 0.000000000005927 78.0
PYH1_k127_5646209_1 Nitroreductase family - - - 0.000000004404 60.0
PYH1_k127_5658372_0 PFAM FecR protein - - - 0.00000000000000003975 98.0
PYH1_k127_5658372_1 Belongs to the ompA family K20276 - - 0.000000000003029 80.0
PYH1_k127_5736353_0 MgtC family K07507 - - 0.0000000000000000000000000000000000002645 150.0
PYH1_k127_5736353_1 TIGRFAM RHS repeat-associated core domain - - - 0.0005188 52.0
PYH1_k127_5740534_0 Archaeal Type IV pilin, N-terminal K01179 - 3.2.1.4 0.000000000001901 83.0
PYH1_k127_5740534_1 Pro-kumamolisin, activation domain - - - 0.0007311 54.0
PYH1_k127_5781322_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 555.0
PYH1_k127_5781322_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 335.0
PYH1_k127_5781322_2 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000005356 171.0
PYH1_k127_5781322_3 Methyltransferase - - - 0.00000000000000000006445 100.0
PYH1_k127_5781322_4 Domain of unknown function (DUF749) - - - 0.0000003018 56.0
PYH1_k127_5793388_0 4-hydroxyphenylacetate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 589.0
PYH1_k127_5793388_1 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000104 217.0
PYH1_k127_5793388_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000003929 108.0
PYH1_k127_5798329_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000001706 82.0
PYH1_k127_5798329_1 Transcription factor zinc-finger - - - 0.000000004871 67.0
PYH1_k127_585813_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 395.0
PYH1_k127_5875159_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000485 79.0
PYH1_k127_5883903_0 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 450.0
PYH1_k127_5883903_1 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 426.0
PYH1_k127_5883903_2 acid synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 387.0
PYH1_k127_5883903_3 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003533 213.0
PYH1_k127_5883903_4 Acylneuraminate cytidylyltransferase K07257 - - 0.0000000000000000000000000000000000000000000000000000000001203 211.0
PYH1_k127_5883903_5 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000001567 188.0
PYH1_k127_5883903_6 deoxyribonuclease IV (phage-T4-induced) activity - - - 0.0000000000000000000000000003349 131.0
PYH1_k127_5916107_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 398.0
PYH1_k127_5916107_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000001577 143.0
PYH1_k127_5916107_2 FMN binding - - - 0.00001526 54.0
PYH1_k127_5931524_0 PFAM Rieske 2Fe-2S domain K15878 - - 0.0000000000453 72.0
PYH1_k127_5931524_1 - - - - 0.000002546 58.0
PYH1_k127_5932736_0 cell redox homeostasis - - - 0.00000000000000000006052 99.0
PYH1_k127_5932736_1 Glutathione peroxidase - - - 0.000000000007607 74.0
PYH1_k127_5932736_2 cytochrome c biogenesis protein K06196 - - 0.0000000447 63.0
PYH1_k127_5939125_0 PFAM Aldehyde dehydrogenase K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 592.0
PYH1_k127_5939125_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 447.0
PYH1_k127_5939125_2 PEP-utilising enzyme, mobile domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 385.0
PYH1_k127_5939125_3 transferase activity, transferring acyl groups K03824 - - 0.000000000000000000000000000007768 128.0
PYH1_k127_5952791_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.444e-240 761.0
PYH1_k127_5952791_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000001349 79.0
PYH1_k127_5958594_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000004972 179.0
PYH1_k127_5958594_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000000000002803 181.0
PYH1_k127_5958594_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000001758 166.0
PYH1_k127_5958594_3 Translin family K07477 - - 0.0000000000000000000000000000001556 134.0
PYH1_k127_5969075_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 466.0
PYH1_k127_5969075_1 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 393.0
PYH1_k127_5969075_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 317.0
PYH1_k127_5969075_3 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000389 197.0
PYH1_k127_5969075_4 integral membrane protein - - - 0.00000002731 64.0
PYH1_k127_5980127_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000012 183.0
PYH1_k127_5988603_0 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000001511 127.0
PYH1_k127_5988603_1 Major facilitator superfamily - - - 0.000000000000000000000004926 116.0
PYH1_k127_5988603_2 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.00000000000006507 81.0
PYH1_k127_5993803_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 409.0
PYH1_k127_5993803_1 Tfp pilus assembly protein FimV - - - 0.00000000000001067 87.0
PYH1_k127_5993803_2 Reeler domain - - - 0.0000000004371 72.0
PYH1_k127_6014314_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 578.0
PYH1_k127_6014314_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.000000000000000000000000000000000000000002758 168.0
PYH1_k127_6038044_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000002315 247.0
PYH1_k127_6038044_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000007136 102.0
PYH1_k127_6038044_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000003052 90.0
PYH1_k127_6055593_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000819 220.0
PYH1_k127_6055593_1 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000004125 138.0
PYH1_k127_6055593_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000002829 134.0
PYH1_k127_6055593_3 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189,K04652 - - 0.000000000000000000000000000000005806 130.0
PYH1_k127_6066705_0 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000003368 199.0
PYH1_k127_6066705_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000007087 149.0
PYH1_k127_6066705_2 - - - - 0.00000000000000000000000000000001819 143.0
PYH1_k127_6066705_3 - - - - 0.0000000000272 68.0
PYH1_k127_6066705_4 - - - - 0.00000008171 64.0
PYH1_k127_6066705_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000008939 57.0
PYH1_k127_6066705_6 Carotene biosynthesis associated membrane protein K14337,K14339 - - 0.0002933 53.0
PYH1_k127_6073778_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 619.0
PYH1_k127_6073778_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000005724 213.0
PYH1_k127_6073778_2 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000008328 175.0
PYH1_k127_6073778_3 DOMON domain-containing protein - - - 0.0000000000667 75.0
PYH1_k127_6073778_4 Rubrerythrin - - - 0.00000003711 64.0
PYH1_k127_6080513_0 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000003878 131.0
PYH1_k127_6080513_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000003372 100.0
PYH1_k127_6080513_2 prohibitin homologues K17080 - - 0.000009517 57.0
PYH1_k127_6087314_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000004819 198.0
PYH1_k127_6087314_1 metallopeptidase activity - - - 0.0000000000004261 82.0
PYH1_k127_6106043_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 550.0
PYH1_k127_6113775_0 CARDB - - - 0.000000001986 71.0
PYH1_k127_6116843_0 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 451.0
PYH1_k127_6116843_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 353.0
PYH1_k127_6116843_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
PYH1_k127_6116843_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000004362 207.0
PYH1_k127_6116843_4 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000001051 115.0
PYH1_k127_6121801_0 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000143 209.0
PYH1_k127_6121801_1 CARDB - - - 0.000003884 60.0
PYH1_k127_612367_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000001698 222.0
PYH1_k127_612367_1 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000003361 153.0
PYH1_k127_6135707_0 CarboxypepD_reg-like domain K13276 - - 0.00000000000001802 89.0
PYH1_k127_6138041_0 OmpA family - - - 0.000005536 59.0
PYH1_k127_6162754_0 CARDB - - - 0.0000000000000000000001489 115.0
PYH1_k127_6162754_1 Ethylbenzene dehydrogenase - - - 0.0000000000000000000001962 115.0
PYH1_k127_6162754_2 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000389 53.0
PYH1_k127_6185163_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 371.0
PYH1_k127_6214471_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002964 276.0
PYH1_k127_6214471_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000007697 157.0
PYH1_k127_6214471_2 Serine threonine protein kinase - - - 0.000000000000000000000000000000000009775 156.0
PYH1_k127_6214471_3 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000000001009 95.0
PYH1_k127_6214471_4 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000788 64.0
PYH1_k127_6260386_0 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 533.0
PYH1_k127_6263363_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000002671 107.0
PYH1_k127_6263363_1 PFAM GvpD gas vesicle - - - 0.000000000000001269 83.0
PYH1_k127_6265606_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000003227 209.0
PYH1_k127_6272875_0 Rhs Family K20276 - - 0.0000000000000005382 93.0
PYH1_k127_6272875_1 WD40 repeat, subgroup - - - 0.00000000001953 78.0
PYH1_k127_6296715_0 Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000000000000000000000000000001947 211.0
PYH1_k127_6296715_1 reductase K00059 - 1.1.1.100 0.00000000000000000000003184 104.0
PYH1_k127_6334262_0 Potassium uptake protein, TrkH family K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 351.0
PYH1_k127_6334262_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 329.0
PYH1_k127_6380827_0 PFAM PKD domain containing protein - - - 0.000000000000007373 85.0
PYH1_k127_6380827_1 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000001384 77.0
PYH1_k127_639478_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000001676 210.0
PYH1_k127_639478_1 Double zinc ribbon - - - 0.000001262 55.0
PYH1_k127_6410576_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 455.0
PYH1_k127_6410576_1 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000002732 181.0
PYH1_k127_6410576_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000004513 161.0
PYH1_k127_642813_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.61e-257 806.0
PYH1_k127_642813_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.821e-231 752.0
PYH1_k127_642813_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000239 250.0
PYH1_k127_642813_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000003139 213.0
PYH1_k127_642813_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000002221 113.0
PYH1_k127_642813_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000001787 92.0
PYH1_k127_642813_6 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.00000000002165 66.0
PYH1_k127_6440163_0 PFAM Tetratricopeptide - - - 0.000000000001515 76.0
PYH1_k127_6440163_1 Elongator protein 3 MiaB NifB - - - 0.00000005864 59.0
PYH1_k127_6471947_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005036 278.0
PYH1_k127_6471947_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000005683 241.0
PYH1_k127_6471947_2 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000001105 155.0
PYH1_k127_6471947_3 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000001455 149.0
PYH1_k127_6471947_4 ABC-2 family transporter protein K01992 - - 0.00000009134 62.0
PYH1_k127_6471947_5 - K01992,K19341 - - 0.000002855 60.0
PYH1_k127_6471947_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.0002445 46.0
PYH1_k127_6486157_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000006022 194.0
PYH1_k127_6486157_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000254 72.0
PYH1_k127_652322_0 Thioredoxin-like - - - 0.00000000000000812 85.0
PYH1_k127_652322_1 - - - - 0.00000002209 60.0
PYH1_k127_6530927_0 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 265.0
PYH1_k127_6530927_1 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000001645 246.0
PYH1_k127_6530927_2 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000007825 191.0
PYH1_k127_6539352_0 Ethanolamine utilisation protein EutQ K06995 - - 0.00000000000000000000000000000000000002152 145.0
PYH1_k127_6539352_1 Fic/DOC family - - - 0.0000000000000000000000000000000000001203 153.0
PYH1_k127_6548247_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 554.0
PYH1_k127_6548247_1 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000002852 171.0
PYH1_k127_6548247_2 GDSL-like Lipase/Acylhydrolase - - - 0.0004464 51.0
PYH1_k127_6548968_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000002904 99.0
PYH1_k127_6554400_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.84e-307 956.0
PYH1_k127_6554400_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 368.0
PYH1_k127_6554400_2 acetate transmembrane transporter activity K07034 - - 0.000000000000000000000000000000000000000007262 158.0
PYH1_k127_6554400_3 Helix-turn-helix domain - - - 0.00000000000000000000002229 103.0
PYH1_k127_6554400_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000005331 104.0
PYH1_k127_6554400_5 Helix-turn-helix domain - - - 0.0000000000000000002499 93.0
PYH1_k127_6554400_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000376 64.0
PYH1_k127_655985_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 361.0
PYH1_k127_655985_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000004705 71.0
PYH1_k127_655985_2 SPFH domain-Band 7 family - - - 0.00000001864 59.0
PYH1_k127_6574675_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000002051 86.0
PYH1_k127_6580010_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 489.0
PYH1_k127_6580010_1 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000004859 140.0
PYH1_k127_6580953_0 amine dehydrogenase activity K20276,K21430 - - 0.00000000000000000000003821 117.0
PYH1_k127_6586592_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 345.0
PYH1_k127_6586592_1 Subtilase family - - - 0.000000000000000003776 89.0
PYH1_k127_6594727_0 PFAM FecR protein - - - 0.0000000000000000000000000005995 134.0
PYH1_k127_6594727_1 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.000000000001483 83.0
PYH1_k127_6603928_0 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000003848 174.0
PYH1_k127_6603928_1 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.00000000000000000000000000000000000002052 149.0
PYH1_k127_663013_0 COG0491 Zn-dependent - - - 0.0000000000000000000000000000000000000000000000009093 183.0
PYH1_k127_663013_1 PKD domain - - - 0.0000000000005334 83.0
PYH1_k127_6632596_0 Belongs to the ompA family K20276 - - 0.000000000000000000006679 110.0
PYH1_k127_6634507_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001092 283.0
PYH1_k127_6634507_1 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000001351 96.0
PYH1_k127_6634507_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000171 71.0
PYH1_k127_6634507_3 Phospholipase_D-nuclease N-terminal - - - 0.000005952 54.0
PYH1_k127_6634507_4 DHH family K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0003194 52.0
PYH1_k127_6652551_0 HEPN domain - - - 0.0000000000000000000001219 105.0
PYH1_k127_6652551_1 SMART Parallel beta-helix repeat - - - 0.000000000004197 80.0
PYH1_k127_6652551_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000002354 65.0
PYH1_k127_6652551_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0001086 53.0
PYH1_k127_6652551_4 Nucleotidyltransferase domain - - - 0.0001175 53.0
PYH1_k127_6653034_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 333.0
PYH1_k127_6653034_1 - - - - 0.00000000000000000000000000000003663 130.0
PYH1_k127_6653034_2 COG2931 RTX toxins and related Ca2 -binding - - - 0.00001922 59.0
PYH1_k127_6657956_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000007475 200.0
PYH1_k127_6657956_1 transcription regulator activity - - - 0.00000000000000000155 92.0
PYH1_k127_6657956_2 transcription regulator activity - - - 0.000000000000000003072 93.0
PYH1_k127_667265_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 309.0
PYH1_k127_667265_1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002427 275.0
PYH1_k127_6674924_0 radical SAM domain protein K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 303.0
PYH1_k127_6674924_2 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000006784 138.0
PYH1_k127_6674924_3 Nodulation protein S (NodS) - - - 0.000000000000000000007252 97.0
PYH1_k127_6674924_4 Glycosyl transferase 4-like domain - - - 0.000000000000001961 88.0
PYH1_k127_6674924_5 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000004651 62.0
PYH1_k127_6679059_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 370.0
PYH1_k127_668861_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000002917 86.0
PYH1_k127_668861_1 Acetyltransferase (GNAT) family - - - 0.000003365 58.0
PYH1_k127_668861_2 Trehalose utilisation - - - 0.00004943 55.0
PYH1_k127_6704793_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 501.0
PYH1_k127_6704793_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 452.0
PYH1_k127_6704793_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 325.0
PYH1_k127_6704793_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000004739 247.0
PYH1_k127_6704793_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000004097 188.0
PYH1_k127_6714310_0 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 511.0
PYH1_k127_6714310_1 Protein of unknown function (DUF835) - - - 0.0009701 50.0
PYH1_k127_6719927_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000007611 187.0
PYH1_k127_6719927_1 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.00000000000000000002054 99.0
PYH1_k127_6719927_2 Bacterio-opsin activator HTH K06930 - - 0.0000000006653 69.0
PYH1_k127_6744250_0 PFAM NADH Ubiquinone plastoquinone (complex I) K14086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 387.0
PYH1_k127_6744250_1 PFAM respiratory-chain NADH dehydrogenase subunit 1 K14087 - - 0.000000000000000000000000000000000000000000000000000000000008857 217.0
PYH1_k127_6744250_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K00331,K14088 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001702 210.0
PYH1_k127_6744250_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000001494 56.0
PYH1_k127_6750470_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1083.0
PYH1_k127_6750470_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2e-226 721.0
PYH1_k127_6750470_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 350.0
PYH1_k127_6750470_3 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000002477 264.0
PYH1_k127_6750470_4 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000009024 205.0
PYH1_k127_6750470_5 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000001853 189.0
PYH1_k127_6750470_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000001277 56.0
PYH1_k127_6750492_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001383 279.0
PYH1_k127_6759666_0 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 401.0
PYH1_k127_6759666_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 320.0
PYH1_k127_6759666_2 component of anaerobic - - - 0.000000000000000001282 91.0
PYH1_k127_677958_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000004548 248.0
PYH1_k127_677958_1 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000008791 133.0
PYH1_k127_677958_2 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000001115 56.0
PYH1_k127_678368_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 376.0
PYH1_k127_678368_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000003812 175.0
PYH1_k127_678368_2 snRNP Sm proteins K04796 - - 0.0000000000000000005342 90.0
PYH1_k127_6784794_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 377.0
PYH1_k127_6784794_1 - - - - 0.000000000000000000000000000000000000000000000000000001558 205.0
PYH1_k127_6784794_2 - - - - 0.0000000000000000000000000000000004542 138.0
PYH1_k127_6798786_0 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 358.0
PYH1_k127_6798786_1 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000008828 265.0
PYH1_k127_6798786_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
PYH1_k127_6798786_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000006841 198.0
PYH1_k127_6798786_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000152 174.0
PYH1_k127_6825421_0 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000003042 128.0
PYH1_k127_6825421_1 M6 family metalloprotease domain protein - - - 0.000000032 68.0
PYH1_k127_6835575_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 569.0
PYH1_k127_6835575_1 M42 glutamyl aminopeptidase K01179,K20609 - 3.2.1.4 0.00000000000009435 75.0
PYH1_k127_6841048_0 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009688 285.0
PYH1_k127_6841048_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000002696 241.0
PYH1_k127_6841048_2 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000002114 130.0
PYH1_k127_6848124_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00001252 58.0
PYH1_k127_6900230_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004885 263.0
PYH1_k127_6900230_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000374 260.0
PYH1_k127_6900230_2 HEPN domain - - - 0.0000000000000000001629 102.0
PYH1_k127_6900230_3 Nucleotidyltransferase domain K07076 - - 0.00000000000003256 77.0
PYH1_k127_6902123_0 domain, Protein K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 314.0
PYH1_k127_6902123_1 ATPase (AAA superfamily) K07133 - - 0.0000000000000000000000006629 119.0
PYH1_k127_6902123_2 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000008663 104.0
PYH1_k127_6902123_3 PKD domain - - - 0.000000000000002539 91.0
PYH1_k127_6902123_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00002448 57.0
PYH1_k127_6905829_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000288 220.0
PYH1_k127_6905829_1 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000006859 218.0
PYH1_k127_6905829_2 Belongs to the glycosyl hydrolase family 6 - - - 0.000007589 59.0
PYH1_k127_6907234_0 DALR anticodon binding domain K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 312.0
PYH1_k127_6907234_1 Inter-alpha-trypsin inhibitor heavy chain - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.00000000000000000000000000000000000000000000000000000000000001059 243.0
PYH1_k127_6907234_2 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000001415 173.0
PYH1_k127_6909155_0 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 358.0
PYH1_k127_6909155_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000135 205.0
PYH1_k127_6909155_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000003974 105.0
PYH1_k127_691001_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 456.0
PYH1_k127_691001_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000008342 113.0
PYH1_k127_6919652_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 442.0
PYH1_k127_6919652_1 Belongs to the UPF0201 family K09736 - - 0.00000003367 59.0
PYH1_k127_6949841_0 RIO1 family K07178 - 2.7.11.1 0.00000000000000000000000000000000002197 145.0
PYH1_k127_6953473_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 368.0
PYH1_k127_6953473_1 Glycosyltransferase Family 4 K00743 - 2.4.1.87 0.000000000000000000000000000000000000000000000000000001286 207.0
PYH1_k127_6953473_2 domain protein - - - 0.00000000000003269 84.0
PYH1_k127_6960568_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 8.153e-211 672.0
PYH1_k127_6960568_1 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000003848 81.0
PYH1_k127_6960568_2 Helix-turn-helix domain - - - 0.00000001312 62.0
PYH1_k127_6960568_3 but it may be involved in stabilization of the trimeric complex - - - 0.000001945 55.0
PYH1_k127_6960568_4 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0003521 45.0
PYH1_k127_696655_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000001559 232.0
PYH1_k127_696655_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000002631 190.0
PYH1_k127_696655_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000001269 180.0
PYH1_k127_6967538_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
PYH1_k127_6967538_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001075 222.0
PYH1_k127_6967538_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000002254 98.0
PYH1_k127_6967538_3 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.0000002188 63.0
PYH1_k127_7011135_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004864 314.0
PYH1_k127_7011135_1 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001778 260.0
PYH1_k127_7018722_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 323.0
PYH1_k127_7018722_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000003296 222.0
PYH1_k127_7018722_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000007395 162.0
PYH1_k127_7018722_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000001811 131.0
PYH1_k127_7018722_4 SMART Parallel beta-helix repeat - - - 0.000000359 64.0
PYH1_k127_7027158_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000001859 174.0
PYH1_k127_7027158_1 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.000000000000000000000000000000001565 133.0
PYH1_k127_7027158_2 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000001363 133.0
PYH1_k127_7028163_0 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000006724 235.0
PYH1_k127_7038610_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 272.0
PYH1_k127_7038610_1 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000001661 169.0
PYH1_k127_7038610_2 adenyl ribonucleotide binding - - - 0.00000000000000000000002616 107.0
PYH1_k127_7038610_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00004899 57.0
PYH1_k127_7053358_0 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000001876 101.0
PYH1_k127_7054034_0 pyrroloquinoline quinone binding K01206,K01218,K01342,K08651,K14645 - 3.2.1.51,3.2.1.78,3.4.21.62,3.4.21.66 0.0000000000000000000000000000006393 144.0
PYH1_k127_7054034_1 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.00000000000000000241 96.0
PYH1_k127_7054034_2 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.000009325 61.0
PYH1_k127_7054034_3 Carbohydrate esterase family 3 protein - - - 0.00004841 58.0
PYH1_k127_7066992_0 Carbohydrate esterase family 3 protein - - - 0.00000000000000000000561 110.0
PYH1_k127_7066992_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000009226 63.0
PYH1_k127_7093774_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003086 277.0
PYH1_k127_7093774_1 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000803 228.0
PYH1_k127_7093774_2 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000585 170.0
PYH1_k127_7093774_3 OmpA family - - - 0.00000068 64.0
PYH1_k127_7093774_4 Clostripain family - - - 0.0002336 56.0
PYH1_k127_7096808_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 394.0
PYH1_k127_7096808_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 329.0
PYH1_k127_7096808_2 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000001575 124.0
PYH1_k127_7103574_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 449.0
PYH1_k127_7103574_1 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000000000000000000002512 133.0
PYH1_k127_7103574_2 PFAM helix-turn-helix domain protein K03627 - - 0.0003197 48.0
PYH1_k127_7108579_0 metallopeptidase activity - - - 0.0000000000000000000000000002445 131.0
PYH1_k127_7108579_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000001826 128.0
PYH1_k127_7113918_0 PFAM aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 337.0
PYH1_k127_7113918_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000001114 222.0
PYH1_k127_7113918_2 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.0000000000007908 73.0
PYH1_k127_7114863_0 PFAM Protein kinase domain - - - 0.000000000000000000000000000001127 136.0
PYH1_k127_7114863_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00004623 51.0
PYH1_k127_7128715_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000001264 246.0
PYH1_k127_7128715_1 PFAM HhH-GPD K07457 - - 0.00000000000000000000000000000000000000000000000000000000000376 215.0
PYH1_k127_7128715_2 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.000000000002801 68.0
PYH1_k127_7128715_3 KaiC - - - 0.000000000008725 74.0
PYH1_k127_7135734_0 CARDB - - - 0.000000000000006116 91.0
PYH1_k127_7137022_0 Transcriptional regulator, ArsR family - - - 0.00000000000000000000000000000123 129.0
PYH1_k127_7141789_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 347.0
PYH1_k127_7141789_1 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002518 302.0
PYH1_k127_7141789_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000006174 137.0
PYH1_k127_7141789_3 Titin-like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000768,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002682,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005863,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006949,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007062,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007498,GO:0007507,GO:0007512,GO:0007517,GO:0007519,GO:0007520,GO:0007522,GO:0007525,GO:0007610,GO:0007626,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0008344,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010638,GO:0010720,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0014902,GO:0015629,GO:0016043,GO:0016192,GO:0016203,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018108,GO:0018193,GO:0018209,GO:0018210,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0030534,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032956,GO:0032970,GO:0032982,GO:0032989,GO:0032991,GO:0033043,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035094,GO:0035095,GO:0035206,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042221,GO:0042325,GO:0042493,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045595,GO:0045597,GO:0045859,GO:0045933,GO:0045989,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051276,GO:0051302,GO:0051338,GO:0051371,GO:0051393,GO:0051493,GO:0051495,GO:0051592,GO:0051606,GO:0051716,GO:0051782,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060284,GO:0060297,GO:0060298,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0060538,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071689,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0110020,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1902115,GO:1902117,GO:1902903,GO:1902905,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.00000000002261 78.0
PYH1_k127_7159725_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000000000000000000000000000000000000000000000000000004801 224.0
PYH1_k127_7159725_1 Putative small multi-drug export protein - - - 0.000000000000000000000000006069 121.0
PYH1_k127_7159725_2 Rhomboid family - - - 0.00000000000000003274 94.0
PYH1_k127_718094_0 PFAM Hemolysin-type calcium-binding repeat (2 copies) K11005,K11029 GO:0001906,GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0006873,GO:0006874,GO:0006875,GO:0007204,GO:0008150,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0019725,GO:0019835,GO:0030003,GO:0031640,GO:0035821,GO:0042592,GO:0044179,GO:0044364,GO:0044419,GO:0044764,GO:0048878,GO:0050801,GO:0051480,GO:0051704,GO:0051715,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0072503,GO:0072507,GO:0098771 4.6.1.1 0.0004774 53.0
PYH1_k127_7182730_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 437.0
PYH1_k127_7182730_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
PYH1_k127_7182730_2 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.00000000000000000000000000000000004283 147.0
PYH1_k127_7182730_4 NOG20192 non supervised orthologous group - - - 0.00000000011 68.0
PYH1_k127_7233177_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 6.647e-271 861.0
PYH1_k127_7233177_1 PRC-barrel domain - - - 0.000000000000000000000000004166 112.0
PYH1_k127_7233177_2 - - - - 0.000000000000000000000002681 114.0
PYH1_k127_7233177_3 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.0000000000861 73.0
PYH1_k127_7233177_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000003112 66.0
PYH1_k127_7233177_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000002158 56.0
PYH1_k127_7233177_6 COG0438 Glycosyltransferase - - - 0.0000002797 63.0
PYH1_k127_7233177_7 protein conserved in archaea - - - 0.00003115 53.0
PYH1_k127_7237308_0 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000001065 181.0
PYH1_k127_7249206_0 helix_turn_helix ASNC type K03718 - - 0.00001963 56.0
PYH1_k127_7254271_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 423.0
PYH1_k127_7264431_0 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 383.0
PYH1_k127_7264431_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000001287 158.0
PYH1_k127_7264431_2 methyltransferase - - - 0.00000000000000005448 92.0
PYH1_k127_7319159_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 390.0
PYH1_k127_7319159_1 - - - - 0.00000000000000000000000000000000000001814 163.0
PYH1_k127_7319159_10 Lrp/AsnC ligand binding domain - - - 0.00004901 49.0
PYH1_k127_7319159_11 Alpha/beta hydrolase family - - - 0.0003059 46.0
PYH1_k127_7319159_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.3.4.1 0.00000000000000000000000000000000002201 148.0
PYH1_k127_7319159_3 - - - - 0.00000000000000000000000000000005528 144.0
PYH1_k127_7319159_4 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000003896 104.0
PYH1_k127_7319159_5 Iron-sulfur cluster binding protein - - - 0.000000000000007577 87.0
PYH1_k127_7319159_6 lactate oxidation - - - 0.00000000004201 71.0
PYH1_k127_7319159_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000004475 63.0
PYH1_k127_7319159_8 rubredoxin - - - 0.000002925 57.0
PYH1_k127_7319159_9 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.0000413 53.0
PYH1_k127_7323998_0 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000002679 109.0
PYH1_k127_7323998_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000005108 79.0
PYH1_k127_7333796_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 535.0
PYH1_k127_7333796_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 395.0
PYH1_k127_7333796_2 Subtilase family K17734 - - 0.0000000000000000000000000000000000589 151.0
PYH1_k127_7333796_3 - - - - 0.0000002819 55.0
PYH1_k127_7341658_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 526.0
PYH1_k127_7341658_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000001836 74.0
PYH1_k127_734290_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 608.0
PYH1_k127_7345904_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 3.281e-204 651.0
PYH1_k127_7345904_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000173 196.0
PYH1_k127_7345904_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000009615 153.0
PYH1_k127_7345904_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000001044 113.0
PYH1_k127_7345904_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000002606 96.0
PYH1_k127_7345904_5 Serine threonine protein K01090 - 3.1.3.16 0.0000000000004187 73.0
PYH1_k127_7345904_6 deoxyhypusine monooxygenase activity - - - 0.00001865 53.0
PYH1_k127_7377687_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 413.0
PYH1_k127_7377687_1 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000001268 131.0
PYH1_k127_7384572_0 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000007126 243.0
PYH1_k127_7384572_1 - - - - 0.000000000000000007448 98.0
PYH1_k127_7400140_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 440.0
PYH1_k127_7400140_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 314.0
PYH1_k127_7400140_2 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000001332 250.0
PYH1_k127_7400140_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000003123 242.0
PYH1_k127_7400140_4 RHS Repeat - - - 0.000000000000000000000000000000000000000000000000000000813 221.0
PYH1_k127_7400140_5 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000005774 187.0
PYH1_k127_7400140_6 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000008546 146.0
PYH1_k127_7400140_7 Belongs to the thioredoxin family K03671 - - 0.0000000000001275 76.0
PYH1_k127_7400140_8 Belongs to the thioredoxin family K03671 - - 0.0000000000004942 73.0
PYH1_k127_7403723_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000007179 192.0
PYH1_k127_7411131_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 341.0
PYH1_k127_7411131_1 domain, Protein - - - 0.0000000000000000000000000000000000000000003032 184.0
PYH1_k127_7411131_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000006387 148.0
PYH1_k127_7411131_3 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose - - - 0.00000000000004701 87.0
PYH1_k127_7445199_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000001453 228.0
PYH1_k127_7445199_1 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.000000000000000000000000000000000000000000000000000001068 211.0
PYH1_k127_7453578_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 581.0
PYH1_k127_7453578_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000009611 60.0
PYH1_k127_7462258_0 Fungalysin metallopeptidase (M36) - - - 0.000000004008 70.0
PYH1_k127_7531805_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 534.0
PYH1_k127_754936_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 340.0
PYH1_k127_754936_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000009467 117.0
PYH1_k127_7563511_0 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 367.0
PYH1_k127_7563511_1 Winged helix DNA-binding domain - - - 0.000000000000000000006892 99.0
PYH1_k127_7563511_2 cellulose binding - - - 0.0000000000000000002784 103.0
PYH1_k127_756883_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1027.0
PYH1_k127_756883_1 Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 383.0
PYH1_k127_756883_2 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001376 268.0
PYH1_k127_756883_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000168 258.0
PYH1_k127_7571280_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 359.0
PYH1_k127_7571280_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 337.0
PYH1_k127_7571280_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000002797 196.0
PYH1_k127_7571280_3 protein conserved in archaea - - - 0.00000000000000000002384 98.0
PYH1_k127_7587632_0 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000003569 166.0
PYH1_k127_7587632_1 oxidase subunit III K02299 - - 0.0000000000000000000000000000001265 134.0
PYH1_k127_7587632_2 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000841 136.0
PYH1_k127_7587632_3 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000004313 131.0
PYH1_k127_7587632_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000002645 113.0
PYH1_k127_7587632_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00007093 47.0
PYH1_k127_7609174_0 amine dehydrogenase activity - - - 0.00000000000000003743 96.0
PYH1_k127_7609174_1 Belongs to the peptidase S8 family - - - 0.00001142 58.0
PYH1_k127_7653561_0 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 276.0
PYH1_k127_7653561_1 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004528 255.0
PYH1_k127_7653561_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000005894 70.0
PYH1_k127_7662968_0 cheY-homologous receiver domain - - - 0.0000000000000000000009769 101.0
PYH1_k127_7662968_1 Flavodoxin - - - 0.0000000001346 70.0
PYH1_k127_7666680_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000008367 96.0
PYH1_k127_7672015_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000005345 151.0
PYH1_k127_7672015_1 transcriptional regulator, SARP family - - - 0.00000000000000000004525 106.0
PYH1_k127_7672015_2 Transcriptional regulator - - - 0.0000000001461 74.0
PYH1_k127_7672015_3 OsmC-like protein - - - 0.000000003447 65.0
PYH1_k127_7672015_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000006963 55.0
PYH1_k127_7672015_5 Reductase C-terminal K00529 - 1.18.1.3 0.0001527 46.0
PYH1_k127_7676599_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 562.0
PYH1_k127_7676599_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 407.0
PYH1_k127_7677487_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 2.12e-208 723.0
PYH1_k127_7677487_1 Thioredoxin domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
PYH1_k127_7677487_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000001489 153.0
PYH1_k127_7677487_3 Type I secretion C-terminal target domain (VC_A0849 subclass) - - - 0.00000000000001705 89.0
PYH1_k127_7684274_0 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000001743 200.0
PYH1_k127_7684274_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000002324 195.0
PYH1_k127_7684274_2 TPR Domain containing protein - - - 0.000000000000000000000000000000000000000000000000355 184.0
PYH1_k127_7684274_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001645 132.0
PYH1_k127_7684932_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000001991 229.0
PYH1_k127_7684932_1 Fibronectin type III domain - - - 0.0000004529 63.0
PYH1_k127_7690749_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 9.73e-286 896.0
PYH1_k127_7690749_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 544.0
PYH1_k127_7690749_2 DEAD/H associated K03724 - - 0.000000000000000000000000000000005303 134.0
PYH1_k127_7690749_3 AAA domain K06873 - - 0.000000000000000000000000002444 124.0
PYH1_k127_7690749_4 FeoA K03709 - - 0.0000000000000000000000001386 114.0
PYH1_k127_7690749_5 OPT oligopeptide transporter protein - - - 0.0000000002138 74.0
PYH1_k127_7706212_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 395.0
PYH1_k127_7706212_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 361.0
PYH1_k127_773134_0 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000001594 59.0
PYH1_k127_7758028_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 357.0
PYH1_k127_7758028_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 282.0
PYH1_k127_7758028_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00007729 48.0
PYH1_k127_7773535_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 484.0
PYH1_k127_7773535_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
PYH1_k127_7774852_0 KH domain K07041 - - 1.288e-256 805.0
PYH1_k127_7774852_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000002386 229.0
PYH1_k127_7783892_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000009733 218.0
PYH1_k127_7783892_1 PA14 domain - - - 0.0000000000000000000000000000000000000000162 178.0
PYH1_k127_7798720_0 COG1290 Cytochrome b subunit of the bc complex - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006682 296.0
PYH1_k127_7809322_0 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 537.0
PYH1_k127_7809322_1 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 462.0
PYH1_k127_7809322_2 E1-E2 ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 320.0
PYH1_k127_7809322_3 YHS domain - - - 0.000000000000000472 89.0
PYH1_k127_7809322_4 Belongs to the peptidase S8 family - - - 0.0000000000000009496 91.0
PYH1_k127_7809322_5 Phospholipase_D-nuclease N-terminal - - - 0.000004375 56.0
PYH1_k127_7809322_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - GO:0001764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0006928,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010721,GO:0010975,GO:0010977,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016477,GO:0022008,GO:0030135,GO:0030136,GO:0030154,GO:0030659,GO:0030662,GO:0030665,GO:0031090,GO:0031344,GO:0031345,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0040011,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0048519,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051129,GO:0051179,GO:0051239,GO:0051241,GO:0051674,GO:0051960,GO:0051961,GO:0060284,GO:0061024,GO:0065007,GO:0071840,GO:0071944,GO:0097708,GO:0098588,GO:0098805,GO:0120035,GO:2000026,GO:2000171 - 0.0006165 53.0
PYH1_k127_7825664_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 351.0
PYH1_k127_7825664_1 Radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 325.0
PYH1_k127_7825664_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000102 204.0
PYH1_k127_7825664_3 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000002457 177.0
PYH1_k127_7825664_4 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000001037 142.0
PYH1_k127_7825664_5 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 0.000000000000004366 76.0
PYH1_k127_7825664_6 homolog of phage Mu protein gp47 - - - 0.000000005047 69.0
PYH1_k127_7835436_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 313.0
PYH1_k127_7835436_1 DNA binding protein K06930 - - 0.000000000000000000004513 104.0
PYH1_k127_7835436_2 KEOPS complex Cgi121-like subunit K09119 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000001036 70.0
PYH1_k127_7860091_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 310.0
PYH1_k127_7860766_0 - - - - 0.00001898 57.0
PYH1_k127_7861673_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 338.0
PYH1_k127_7870731_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003208 303.0
PYH1_k127_7887384_0 PFAM PilT protein domain protein K06865 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 421.0
PYH1_k127_7887384_1 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001616 271.0
PYH1_k127_7890308_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 299.0
PYH1_k127_7890308_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000002515 174.0
PYH1_k127_7896421_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 554.0
PYH1_k127_7896421_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000004098 198.0
PYH1_k127_7896421_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000005347 144.0
PYH1_k127_7896421_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000001113 143.0
PYH1_k127_7896421_4 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000008463 129.0
PYH1_k127_7896421_5 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000000006172 133.0
PYH1_k127_7896421_6 Activator of Hsp90 ATPase - - - 0.000000000000000000000000001904 119.0
PYH1_k127_7896421_7 Domain of unknown function (DU1801) - - - 0.00000000000000002315 86.0
PYH1_k127_7896421_8 choline dehydrogenase activity - - - 0.0007936 44.0
PYH1_k127_7896421_9 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000812 51.0
PYH1_k127_7944794_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000004295 203.0
PYH1_k127_7944794_1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0003474 51.0
PYH1_k127_7946827_0 cellular potassium ion transport K03499 - - 0.00000000000000000000000005085 114.0
PYH1_k127_7946827_1 virion core protein, lumpy skin disease virus - - - 0.0000007237 63.0
PYH1_k127_7950623_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.543e-315 997.0
PYH1_k127_7960614_0 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001578 250.0
PYH1_k127_7960614_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000479 181.0
PYH1_k127_7960614_2 COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit K07398 - - 0.0000000000000000000000002987 108.0
PYH1_k127_7960614_3 COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit K07398 - - 0.0000000000000001971 82.0
PYH1_k127_7974235_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000003708 186.0
PYH1_k127_798482_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.519e-264 827.0
PYH1_k127_798482_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 578.0
PYH1_k127_798482_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 456.0
PYH1_k127_798482_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 383.0
PYH1_k127_798482_4 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 379.0
PYH1_k127_798482_5 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000001833 236.0
PYH1_k127_798482_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000004384 114.0
PYH1_k127_798482_7 UPF0056 membrane protein K05595 - - 0.00000000000005641 81.0
PYH1_k127_798482_8 Transcriptional regulator K07722 - - 0.00000007819 61.0
PYH1_k127_8002225_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000008855 237.0
PYH1_k127_8002225_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000002095 156.0
PYH1_k127_8002225_2 iron dependent repressor - - - 0.00002488 55.0
PYH1_k127_8020071_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000001691 93.0
PYH1_k127_8020071_1 MacB-like periplasmic core domain K02004 - - 0.0000000001033 75.0
PYH1_k127_8043603_0 Domain of unknown function DUF11 - - - 0.0000585 57.0
PYH1_k127_8081564_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000008943 151.0
PYH1_k127_8087596_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002631 250.0
PYH1_k127_8087596_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000001264 150.0
PYH1_k127_8087596_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000001324 72.0
PYH1_k127_8087596_4 DUF3160 - - - 0.0000004209 55.0
PYH1_k127_8102655_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000335 141.0
PYH1_k127_8109385_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 462.0
PYH1_k127_8109385_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000001403 89.0
PYH1_k127_8117747_0 PFAM peptidase M42 - - - 0.00000000000000000000000000000000000000001215 169.0
PYH1_k127_8117747_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000002563 154.0
PYH1_k127_8147584_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 459.0
PYH1_k127_8181917_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000007162 105.0
PYH1_k127_8181917_1 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.00000000000000003261 98.0
PYH1_k127_8191821_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000009618 89.0
PYH1_k127_8191821_1 Pkd domain containing protein - - - 0.000000000001822 81.0
PYH1_k127_8191821_2 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000005667 58.0
PYH1_k127_8193402_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.01e-246 774.0
PYH1_k127_8207384_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 392.0
PYH1_k127_8207384_1 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 364.0
PYH1_k127_8207384_2 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 347.0
PYH1_k127_8207384_3 reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
PYH1_k127_8207384_4 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000002656 175.0
PYH1_k127_8207384_5 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000002699 93.0
PYH1_k127_8207384_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000003123 94.0
PYH1_k127_8207384_7 Hydrogenase maturation protease K03605 - - 0.00000000000000001983 91.0
PYH1_k127_8207384_8 Hydrogenase maturation protease K03605 - - 0.000000000002296 74.0
PYH1_k127_8207384_9 HypF finger K04656 - - 0.0003852 45.0
PYH1_k127_823212_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000001121 190.0
PYH1_k127_823212_1 PKD domain K19668 - 3.2.1.91 0.00000000000000000000005293 115.0
PYH1_k127_823212_2 pfam abc K18232 - - 0.0000000000000000000001053 105.0
PYH1_k127_823212_3 YHS domain - - - 0.0000000000000000001182 91.0
PYH1_k127_823212_4 Belongs to the glycosyl hydrolase 43 family K01278,K03561,K12287 - 3.4.14.5 0.000001142 56.0
PYH1_k127_8264521_1 - - - - 0.000000001166 67.0
PYH1_k127_8264521_2 Pkd domain containing protein K20276 - - 0.0000003488 63.0
PYH1_k127_8286083_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.838e-261 821.0
PYH1_k127_8308688_0 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.397e-256 829.0
PYH1_k127_8308688_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.346e-221 700.0
PYH1_k127_8308688_10 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000004204 226.0
PYH1_k127_8308688_11 4Fe-4S dicluster domain K00196,K05796 - - 0.0000000000000000000193 96.0
PYH1_k127_8308688_12 Predicted RNA-binding protein - - - 0.0000001749 55.0
PYH1_k127_8308688_13 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0002417 50.0
PYH1_k127_8308688_2 carbon-monoxide dehydrogenase catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 621.0
PYH1_k127_8308688_3 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 511.0
PYH1_k127_8308688_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 387.0
PYH1_k127_8308688_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 361.0
PYH1_k127_8308688_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 349.0
PYH1_k127_8308688_7 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000001702 267.0
PYH1_k127_8308688_8 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000008158 238.0
PYH1_k127_8308688_9 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000003555 229.0
PYH1_k127_8319233_0 COG1361 S-layer domain - - - 0.0000000000002666 85.0
PYH1_k127_8330161_0 - - - - 0.000000000000000000000000002174 117.0
PYH1_k127_8330161_1 HAD-hyrolase-like K01560 - 3.8.1.2 0.000000000000000000000001742 112.0
PYH1_k127_8330161_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000001628 106.0
PYH1_k127_8330161_3 elongation factor G domain IV K02355 - - 0.00003406 55.0
PYH1_k127_8330161_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0002538 53.0
PYH1_k127_8331087_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000002608 174.0
PYH1_k127_8331087_1 - - - - 0.0000003613 63.0
PYH1_k127_8331087_2 RIO1 family K08851 - 2.7.11.1 0.0000006857 53.0
PYH1_k127_8331087_3 Belongs to the peptidase S8 family - - - 0.000001094 62.0
PYH1_k127_8340996_0 AIR synthase related protein domain protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 467.0
PYH1_k127_8340996_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 393.0
PYH1_k127_8340996_2 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 375.0
PYH1_k127_8340996_3 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000002957 234.0
PYH1_k127_8340996_4 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.0000000000000000001437 98.0
PYH1_k127_8340996_5 cell redox homeostasis - - - 0.0000000000000000006598 89.0
PYH1_k127_8351470_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 416.0
PYH1_k127_8351470_1 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000009009 222.0
PYH1_k127_8351470_2 oxidoreductase subunit delta K00171 - 1.2.7.1 0.000000000000000000000000006053 113.0
PYH1_k127_8351470_3 PKD domain-containing protein - - - 0.0000000001318 75.0
PYH1_k127_8351470_4 Carbohydrate family 9 binding domain-like - - - 0.000001571 62.0
PYH1_k127_8351470_5 Periplasmic copper-binding protein (NosD) - - - 0.0002972 54.0
PYH1_k127_8355102_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006363 236.0
PYH1_k127_84771_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 448.0
PYH1_k127_84771_1 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005164 308.0
PYH1_k127_84771_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000006561 141.0
PYH1_k127_84771_3 CYTH K05873 - 4.6.1.1 0.000000000000000000000000000000494 133.0
PYH1_k127_84771_4 myosin light chain kinase activity K12567 - 2.7.11.1 0.00000000000000000000000000008163 136.0
PYH1_k127_84771_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082,K11752,K14654 - 1.1.1.193,1.1.1.302,3.5.4.26 0.00000000000003265 76.0
PYH1_k127_84771_6 Belongs to the glycosyl hydrolase family 6 - - - 0.000000005473 71.0
PYH1_k127_84771_7 FR47-like protein - - - 0.0001663 53.0
PYH1_k127_84771_8 Flavodoxin domain - - - 0.0006455 53.0
PYH1_k127_861389_0 acetyltransferase - - - 0.000000000000000000000000000000000002553 141.0
PYH1_k127_867509_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006074 278.0
PYH1_k127_867509_1 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000001407 96.0
PYH1_k127_897274_0 KaiC K08482 - - 0.000000000000000000000007284 111.0
PYH1_k127_897274_1 TIGRFAM methyltransferase FkbM - - - 0.000000000000000000009641 106.0
PYH1_k127_897274_2 Belongs to the glycosyl hydrolase family 6 - - - 0.00000002749 66.0
PYH1_k127_897503_0 PFAM FecR protein - - - 0.000000000004102 80.0
PYH1_k127_910027_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 331.0
PYH1_k127_910027_1 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.000000000000000000000000000000005532 150.0
PYH1_k127_910027_2 Fibronectin type III domain - - - 0.000000000000000000002504 102.0
PYH1_k127_92074_0 PFAM FecR protein - - - 0.00000000000000000000007389 117.0
PYH1_k127_92074_1 Fibronectin type 3 domain - - - 0.0000000000004485 85.0
PYH1_k127_92434_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 568.0
PYH1_k127_92434_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 329.0
PYH1_k127_92434_2 small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000002366 254.0
PYH1_k127_92434_3 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000001227 228.0
PYH1_k127_92434_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000003625 161.0
PYH1_k127_92434_5 KaiC K08482 - - 0.00000000000000000000000000000001173 137.0
PYH1_k127_92434_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 2.7.7.3 0.000000000000000000000000000004374 125.0
PYH1_k127_92434_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000286 63.0
PYH1_k127_92434_8 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.000000005697 61.0
PYH1_k127_92434_9 SMART AAA ATPase K08482 - - 0.00002077 55.0
PYH1_k127_936186_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000002494 102.0
PYH1_k127_936186_1 Transcriptional regulator - - - 0.0000000000000004232 87.0
PYH1_k127_936186_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.00000000001843 74.0
PYH1_k127_954755_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 340.0
PYH1_k127_954755_1 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000004446 233.0
PYH1_k127_954755_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000005731 215.0
PYH1_k127_954755_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000001227 211.0
PYH1_k127_954755_4 glyoxalase III activity K13653 - - 0.0000000000000000000000000000971 130.0
PYH1_k127_954755_5 PKD domain - - - 0.00000000000000000000002171 109.0
PYH1_k127_954755_6 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.0000000000009565 69.0
PYH1_k127_954755_7 Participates in transcription termination K02600 - - 0.00000000004933 71.0
PYH1_k127_954755_8 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13638 - - 0.000005823 58.0
PYH1_k127_954755_9 Lrp/AsnC ligand binding domain - - - 0.0000926 49.0
PYH1_k127_959579_0 Thioredoxin-like domain - - - 0.0000000000000003413 94.0
PYH1_k127_961452_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 7.416e-194 619.0
PYH1_k127_961452_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000007662 263.0
PYH1_k127_984627_0 PKD domain - - - 0.00000000000003268 87.0
PYH1_k127_984627_1 Belongs to the UPF0235 family K09131 - - 0.000002452 51.0
PYH1_k127_984627_2 Plexin repeat - GO:0003674,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007186,GO:0007272,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008366,GO:0009987,GO:0016020,GO:0016021,GO:0021549,GO:0022008,GO:0022037,GO:0023052,GO:0030154,GO:0030182,GO:0030902,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0038023,GO:0040008,GO:0040014,GO:0042552,GO:0043473,GO:0044421,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048468,GO:0048513,GO:0048638,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051239,GO:0051716,GO:0060089,GO:0060322,GO:0065007,GO:0071944 - 0.00004081 57.0
PYH1_k127_991569_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 328.0
PYH1_k127_991569_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.0000000000000000000000000000003401 143.0
PYH1_k127_999494_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 448.0
PYH1_k127_999494_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 349.0
PYH1_k127_999494_2 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0