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Overview

ID MAG03149
Name PYH1_bin.43
Sample SMP0073
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order 40CM-2-53-6
Family 40CM-2-53-6
Genus
Species
Assembly information
Completeness (%) 83.42
Contamination (%) 5.38
GC content (%) 53.0
N50 (bp) 11,387
Genome size (bp) 2,066,244

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1916

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_100323_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 426.0
PYH1_k127_100323_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 369.0
PYH1_k127_100323_10 helix_turn_helix ASNC type K03719 - - 0.0000000000000000002769 93.0
PYH1_k127_100323_11 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide K01574 - 4.1.1.4 0.00000000003168 72.0
PYH1_k127_100323_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 366.0
PYH1_k127_100323_3 PFAM Metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 314.0
PYH1_k127_100323_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 297.0
PYH1_k127_100323_5 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003622 290.0
PYH1_k127_100323_6 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000002246 266.0
PYH1_k127_100323_7 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000007393 221.0
PYH1_k127_100323_8 - - - - 0.000000000000000000000000000000000000000000002771 173.0
PYH1_k127_100323_9 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.00000000000000000000000000000001535 142.0
PYH1_k127_1019298_0 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.489e-240 760.0
PYH1_k127_1019298_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 8.116e-220 694.0
PYH1_k127_1019298_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000001727 171.0
PYH1_k127_1019298_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000005251 133.0
PYH1_k127_1019298_12 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000001554 95.0
PYH1_k127_1019298_2 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 463.0
PYH1_k127_1019298_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
PYH1_k127_1019298_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
PYH1_k127_1019298_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 306.0
PYH1_k127_1019298_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00175 - 1.2.7.1,1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
PYH1_k127_1019298_7 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001165 260.0
PYH1_k127_1019298_8 Protein of unknown function (DUF554) K07150 - - 0.000000000000000000000000000000000000000000000000000000000000003166 224.0
PYH1_k127_1019298_9 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000003628 186.0
PYH1_k127_1025284_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 308.0
PYH1_k127_1025284_1 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000001778 72.0
PYH1_k127_1030978_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 413.0
PYH1_k127_1030978_1 Alpha beta hydrolase - - - 0.00000000000000000000000000003354 122.0
PYH1_k127_1030978_2 TIGRFAM cysteine desulfurase family protein - - - 0.0000000001911 65.0
PYH1_k127_1030978_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034,K00059,K04708 - 1.1.1.100,1.1.1.102,1.1.1.47 0.0001318 46.0
PYH1_k127_106506_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 411.0
PYH1_k127_106506_1 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
PYH1_k127_106506_10 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000001594 62.0
PYH1_k127_106506_2 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001302 269.0
PYH1_k127_106506_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002405 215.0
PYH1_k127_106506_4 - - - - 0.00000000000000000000000000000000000000000000000000102 192.0
PYH1_k127_106506_5 amino acid - - - 0.00000000000000000000000000000000000001603 162.0
PYH1_k127_106506_6 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000000000000000000000000000000000004749 142.0
PYH1_k127_106506_7 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000001051 139.0
PYH1_k127_106506_8 protein possibly involved in utilization of glycolate and propanediol - - - 0.00000000000000000000000000006685 119.0
PYH1_k127_106506_9 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000001948 77.0
PYH1_k127_1079256_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 7.479e-300 957.0
PYH1_k127_1079256_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 6.281e-220 691.0
PYH1_k127_1079256_10 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000001724 179.0
PYH1_k127_1079256_11 COG0778 Nitroreductase K10678,K19285 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016657,GO:0032553,GO:0034567,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.38 0.000000000000000000000000000000008194 137.0
PYH1_k127_1079256_12 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000003315 124.0
PYH1_k127_1079256_13 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.000000000000000000000007517 107.0
PYH1_k127_1079256_14 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000008442 98.0
PYH1_k127_1079256_15 Transcriptional regulator K11924 - - 0.000000000000007218 80.0
PYH1_k127_1079256_16 PFAM Transcription elongation factor Elf1 like - - - 0.0000000000008787 72.0
PYH1_k127_1079256_18 - - - - 0.000001485 52.0
PYH1_k127_1079256_19 Lrp/AsnC ligand binding domain - - - 0.00000294 52.0
PYH1_k127_1079256_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 550.0
PYH1_k127_1079256_20 Lrp/AsnC ligand binding domain - - - 0.00002144 51.0
PYH1_k127_1079256_21 - - - - 0.00003245 54.0
PYH1_k127_1079256_22 - - - - 0.00006235 53.0
PYH1_k127_1079256_23 Protein of unknown function (DUF2721) - - - 0.0003206 49.0
PYH1_k127_1079256_24 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0004335 47.0
PYH1_k127_1079256_3 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 467.0
PYH1_k127_1079256_4 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 362.0
PYH1_k127_1079256_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 355.0
PYH1_k127_1079256_6 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 343.0
PYH1_k127_1079256_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 302.0
PYH1_k127_1079256_8 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001614 283.0
PYH1_k127_1079256_9 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000001301 213.0
PYH1_k127_1094919_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 520.0
PYH1_k127_1094919_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 479.0
PYH1_k127_1094919_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001845 263.0
PYH1_k127_1094919_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000001388 76.0
PYH1_k127_1139340_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004897 254.0
PYH1_k127_1139340_1 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000003981 195.0
PYH1_k127_1149786_0 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 434.0
PYH1_k127_1149786_1 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 365.0
PYH1_k127_1149786_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000001944 186.0
PYH1_k127_1149786_3 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000008221 181.0
PYH1_k127_1149786_4 DHHA1 domain K07463 - - 0.00000000000001676 76.0
PYH1_k127_1149786_5 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000007598 78.0
PYH1_k127_1149786_6 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.00001341 53.0
PYH1_k127_1157596_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 566.0
PYH1_k127_1157596_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 516.0
PYH1_k127_1157596_10 phosphatase activity K05967 - - 0.0000000000000003548 86.0
PYH1_k127_1157596_11 Diphthamide synthase - - - 0.0000000000756 66.0
PYH1_k127_1157596_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 387.0
PYH1_k127_1157596_3 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 329.0
PYH1_k127_1157596_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002427 214.0
PYH1_k127_1157596_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001694 154.0
PYH1_k127_1157596_6 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000001158 99.0
PYH1_k127_1157596_7 Peptidase M1 membrane alanine aminopeptidase - - - 0.0000000000000000000008029 108.0
PYH1_k127_1157596_8 Belongs to the MCM family K02212 GO:0000003,GO:0000228,GO:0000278,GO:0000724,GO:0000725,GO:0000727,GO:0000785,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003688,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005656,GO:0005657,GO:0005694,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006267,GO:0006268,GO:0006270,GO:0006271,GO:0006275,GO:0006279,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022607,GO:0022616,GO:0030874,GO:0030875,GO:0031261,GO:0031298,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032780,GO:0032991,GO:0032993,GO:0033043,GO:0033044,GO:0033260,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0036387,GO:0036388,GO:0042555,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043462,GO:0043565,GO:0043596,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044454,GO:0044464,GO:0044786,GO:0045005,GO:0045934,GO:0046483,GO:0048478,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051095,GO:0051097,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051321,GO:0051336,GO:0051346,GO:0051716,GO:0060255,GO:0065003,GO:0065004,GO:0065007,GO:0065009,GO:0070013,GO:0071103,GO:0071162,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097373,GO:1901360,GO:1901363,GO:1901576,GO:1902292,GO:1902299,GO:1902315,GO:1902449,GO:1902450,GO:1902969,GO:1902975,GO:1903046,GO:1903047,GO:1905462,GO:1905463,GO:1905774,GO:1905775,GO:1990837,GO:2000104,GO:2000112,GO:2000113,GO:2001251 3.6.4.12 0.000000000000000000001159 107.0
PYH1_k127_1157596_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000004116 97.0
PYH1_k127_1157963_0 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 413.0
PYH1_k127_1157963_1 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000008671 222.0
PYH1_k127_1157963_2 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.000000000000000000000000000000002799 136.0
PYH1_k127_1173092_0 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 556.0
PYH1_k127_1173092_1 adenosylhomocysteinase activity K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 556.0
PYH1_k127_1173092_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 479.0
PYH1_k127_1173092_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 360.0
PYH1_k127_1173092_4 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 321.0
PYH1_k127_1173092_5 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000001625 123.0
PYH1_k127_1173092_6 4Fe-4S double cluster binding domain - - - 0.000000000414 70.0
PYH1_k127_1242888_0 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 475.0
PYH1_k127_1242888_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 299.0
PYH1_k127_1242888_2 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 - 2.1.1.14 0.00000000000000000000000000000000000001304 157.0
PYH1_k127_1242888_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000002568 144.0
PYH1_k127_1403721_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 577.0
PYH1_k127_1403721_1 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000121 156.0
PYH1_k127_1403721_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000004775 121.0
PYH1_k127_1403721_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000004553 109.0
PYH1_k127_1403721_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000009713 101.0
PYH1_k127_1403721_5 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000512 79.0
PYH1_k127_1403721_6 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000001081 74.0
PYH1_k127_1445504_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 376.0
PYH1_k127_1445504_1 pyruvate-flavodoxin oxidoreductase activity - - - 0.00000000000000000000000000000000003169 136.0
PYH1_k127_1445504_2 PFAM Radical SAM - - - 0.0000000000000000000000000002277 128.0
PYH1_k127_1445504_3 pyruvate-flavodoxin oxidoreductase activity - - - 0.00000006674 57.0
PYH1_k127_145346_0 dihydrodipicolinate reductase K03340,K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.16,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
PYH1_k127_145346_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000542 289.0
PYH1_k127_145346_2 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006953 276.0
PYH1_k127_145346_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000004966 206.0
PYH1_k127_145346_4 PFAM B12 binding domain - - - 0.00000000000000000000000000000000000000000000000003518 186.0
PYH1_k127_1458181_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 537.0
PYH1_k127_1458181_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 368.0
PYH1_k127_1458181_2 Peptidase family M20/M25/M40 K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 322.0
PYH1_k127_1458181_3 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000464 194.0
PYH1_k127_1458181_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K19548 - 1.1.1.385 0.00000000000000000000000000000000000017 145.0
PYH1_k127_1458181_5 converts alpha-aldose to the beta-anomer - - - 0.0001407 48.0
PYH1_k127_1458181_6 dUTPase K01494 - 3.5.4.13 0.0004185 44.0
PYH1_k127_1470522_0 transport system permease component - - - 0.0000000000000000000000000000000000000001636 161.0
PYH1_k127_1470522_1 binding-protein-dependent transport systems inner membrane component - - - 0.000000000000000000000428 104.0
PYH1_k127_1470522_2 COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - - 0.0009868 47.0
PYH1_k127_1491129_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000001093 224.0
PYH1_k127_1491129_1 - - - - 0.0001645 51.0
PYH1_k127_1537493_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 5.041e-212 684.0
PYH1_k127_1537493_1 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 479.0
PYH1_k127_1537493_2 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 376.0
PYH1_k127_1537493_3 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000008573 233.0
PYH1_k127_1537493_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K18021 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.5.3,1.2.99.8 0.00000000000000000000000000000000000000000000000000000000000000001666 234.0
PYH1_k127_1537493_5 2Fe-2S -binding domain K03518,K18022 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114 1.2.5.3,1.2.99.8 0.0000000000000000000000000000000000000000000000000000000000192 210.0
PYH1_k127_1537493_6 2Fe-2S -binding domain K03518,K18022 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114 1.2.5.3,1.2.99.8 0.0000000000000000000000000000000000000000000000000002033 189.0
PYH1_k127_1537493_8 Protein of unknown function (DUF2877) - - - 0.0000001773 63.0
PYH1_k127_1537493_9 Membrane - - - 0.0001222 46.0
PYH1_k127_1554210_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000674 277.0
PYH1_k127_1554210_1 UPF0056 membrane protein K05595 - - 0.000000000000000000001474 103.0
PYH1_k127_1554210_2 PGAP1-like protein - - - 0.00000000000003338 76.0
PYH1_k127_1554210_3 - - - - 0.00000000005983 72.0
PYH1_k127_1587068_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 367.0
PYH1_k127_1587068_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
PYH1_k127_1587068_2 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000002629 235.0
PYH1_k127_1587068_3 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000369 141.0
PYH1_k127_1587068_4 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000006266 101.0
PYH1_k127_1587068_5 NADPH-dependent FMN reductase - - - 0.0000000000000000008793 91.0
PYH1_k127_1593047_0 pyruvate decarboxylase activity K04103 - 4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 443.0
PYH1_k127_1593047_1 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 0.000000000002298 78.0
PYH1_k127_161037_0 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 318.0
PYH1_k127_161037_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000002221 181.0
PYH1_k127_161037_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000003465 144.0
PYH1_k127_161037_3 - - - - 0.000003005 54.0
PYH1_k127_1678401_0 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 437.0
PYH1_k127_1678401_1 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000004337 205.0
PYH1_k127_1678401_2 nodulation - - - 0.00000000000000000000000000000000000000000000005279 184.0
PYH1_k127_1683428_0 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 443.0
PYH1_k127_1683428_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000265 181.0
PYH1_k127_1683428_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000002952 171.0
PYH1_k127_1683428_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000002571 110.0
PYH1_k127_1683428_4 EamA-like transporter family - - - 0.000000000000000000000003565 113.0
PYH1_k127_1683428_5 COG1522 Transcriptional regulators - - - 0.00000000000000001369 85.0
PYH1_k127_1683428_6 Heavy metal translocating P-type atpase - - - 0.0000000000007389 78.0
PYH1_k127_1683428_7 Conserved protein implicated in secretion - - - 0.000000000594 62.0
PYH1_k127_1683428_8 - - - - 0.00002192 52.0
PYH1_k127_1695642_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000008489 130.0
PYH1_k127_1695642_1 Peptidase C13 family - - - 0.0000000000000000005288 101.0
PYH1_k127_1695642_2 Belongs to the ubiquitin-conjugating enzyme family K04649 GO:0000209,GO:0000502,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0016043,GO:0016050,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0030433,GO:0031625,GO:0032446,GO:0032991,GO:0033554,GO:0034976,GO:0036211,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0051716,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070647,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1902494,GO:1905368,GO:1905369 2.3.2.23 0.000000004009 65.0
PYH1_k127_1695642_3 - - - - 0.000458 48.0
PYH1_k127_1750031_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 511.0
PYH1_k127_1750031_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 313.0
PYH1_k127_1750031_2 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000003172 198.0
PYH1_k127_1750031_3 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000002189 133.0
PYH1_k127_1750031_4 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K00332 - 1.6.5.3 0.00000000000000000000000000000009247 131.0
PYH1_k127_1750031_5 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000001378 106.0
PYH1_k127_1750031_6 Thiamine-phosphate synthase K22206 - - 0.00000000478 62.0
PYH1_k127_175677_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1041.0
PYH1_k127_175677_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 464.0
PYH1_k127_175677_10 TOBE domain - - - 0.000000000000000000002311 94.0
PYH1_k127_175677_11 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000427 104.0
PYH1_k127_175677_13 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000002617 59.0
PYH1_k127_175677_2 l-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 383.0
PYH1_k127_175677_3 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 327.0
PYH1_k127_175677_4 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006809 269.0
PYH1_k127_175677_5 PFAM Major facilitator superfamily MFS-1 - - - 0.00000000000000000000000000000000000000000000000000000000000000005773 235.0
PYH1_k127_175677_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000905 216.0
PYH1_k127_175677_7 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
PYH1_k127_175677_8 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000003034 204.0
PYH1_k127_175677_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000002122 171.0
PYH1_k127_1778456_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 462.0
PYH1_k127_1778456_1 NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000044 199.0
PYH1_k127_1778910_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.228e-287 898.0
PYH1_k127_1778910_1 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 2.75e-198 630.0
PYH1_k127_1778910_10 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 272.0
PYH1_k127_1778910_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001413 264.0
PYH1_k127_1778910_12 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000194 248.0
PYH1_k127_1778910_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000006212 237.0
PYH1_k127_1778910_14 PFAM Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000007311 211.0
PYH1_k127_1778910_15 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000007461 212.0
PYH1_k127_1778910_16 COG1290 Cytochrome b subunit of the bc complex - - - 0.00000000000000000000000000000000000000000000000000000905 208.0
PYH1_k127_1778910_17 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000001479 204.0
PYH1_k127_1778910_18 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000001607 167.0
PYH1_k127_1778910_19 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000005642 146.0
PYH1_k127_1778910_2 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 429.0
PYH1_k127_1778910_20 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000009512 139.0
PYH1_k127_1778910_21 - - - - 0.0000000000000000000000000000000078 133.0
PYH1_k127_1778910_22 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000002926 121.0
PYH1_k127_1778910_23 Transcription elongation factor - - - 0.00000000000000000001636 97.0
PYH1_k127_1778910_24 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000001014 89.0
PYH1_k127_1778910_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000001383 83.0
PYH1_k127_1778910_26 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000009308 76.0
PYH1_k127_1778910_27 - - - - 0.00000009385 57.0
PYH1_k127_1778910_28 - - - - 0.000001851 52.0
PYH1_k127_1778910_3 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 431.0
PYH1_k127_1778910_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 399.0
PYH1_k127_1778910_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 381.0
PYH1_k127_1778910_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 348.0
PYH1_k127_1778910_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 349.0
PYH1_k127_1778910_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 334.0
PYH1_k127_1778910_9 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002883 289.0
PYH1_k127_1781896_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000005556 177.0
PYH1_k127_1781896_1 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000003613 153.0
PYH1_k127_1790128_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 474.0
PYH1_k127_1790128_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000003948 192.0
PYH1_k127_1790128_2 B12 binding domain K16179 - - 0.0000000000000000000000000000000000000031 155.0
PYH1_k127_1807258_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.697e-301 942.0
PYH1_k127_1807258_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 335.0
PYH1_k127_1807258_10 - - - - 0.000000000000000000000002659 108.0
PYH1_k127_1807258_11 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000005787 106.0
PYH1_k127_1807258_12 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000008266 86.0
PYH1_k127_1807258_13 Belongs to the UPF0215 family K09120 - - 0.000000000000000008302 91.0
PYH1_k127_1807258_14 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000227 70.0
PYH1_k127_1807258_15 Ribonuclease III - - - 0.0000001146 59.0
PYH1_k127_1807258_16 protein conserved in archaea K09723 - - 0.000002617 57.0
PYH1_k127_1807258_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001152 273.0
PYH1_k127_1807258_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001612 259.0
PYH1_k127_1807258_4 Diphthamide K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000008936 246.0
PYH1_k127_1807258_5 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000007441 226.0
PYH1_k127_1807258_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.00000000000000000000000000000000000000000000000006686 187.0
PYH1_k127_1807258_7 Methyltransferase K07579 - - 0.000000000000000000000000000000000000000001287 164.0
PYH1_k127_1807258_8 Thioredoxin K03671 - - 0.000000000000000000000000000003446 125.0
PYH1_k127_1807258_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000001689 122.0
PYH1_k127_1816145_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
PYH1_k127_1816145_1 membrane protein domain - - - 0.00000003873 55.0
PYH1_k127_1828753_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000001812 142.0
PYH1_k127_1828753_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000004844 79.0
PYH1_k127_1828753_2 COGs COG1082 Sugar phosphate isomerase epimerase - - - 0.000000000000056 82.0
PYH1_k127_1828753_3 PFAM Uncharacterised BCR, COG1649 - - - 0.000213 46.0
PYH1_k127_1842669_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 303.0
PYH1_k127_1842669_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004706 246.0
PYH1_k127_1842669_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000001342 201.0
PYH1_k127_188163_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000001742 245.0
PYH1_k127_188163_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000002873 231.0
PYH1_k127_188163_2 NhaP-type Na H and K H K03316 - - 0.0000000000000000000000000000000000000000000008171 181.0
PYH1_k127_188163_3 zinc finger - - - 0.000000000000000000000000000000000000000000587 166.0
PYH1_k127_188163_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000004592 71.0
PYH1_k127_188163_5 - - - - 0.00002021 52.0
PYH1_k127_1924361_0 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000006745 109.0
PYH1_k127_1932493_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
PYH1_k127_1932493_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000002889 248.0
PYH1_k127_1937717_0 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 391.0
PYH1_k127_1937717_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
PYH1_k127_1937717_10 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000001465 196.0
PYH1_k127_1937717_11 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000004046 175.0
PYH1_k127_1937717_12 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000001247 156.0
PYH1_k127_1937717_13 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000008971 132.0
PYH1_k127_1937717_14 CBS domain - - - 0.0000000000000000000000000000003706 130.0
PYH1_k127_1937717_15 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000003029 125.0
PYH1_k127_1937717_16 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768,K07151 - 2.4.99.18,5.2.1.8 0.000000000002219 81.0
PYH1_k127_1937717_17 - - - - 0.000000188 58.0
PYH1_k127_1937717_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 342.0
PYH1_k127_1937717_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 303.0
PYH1_k127_1937717_4 Spermidine putrescine-binding periplasmic protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000015 267.0
PYH1_k127_1937717_5 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002459 248.0
PYH1_k127_1937717_6 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 237.0
PYH1_k127_1937717_7 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000003025 228.0
PYH1_k127_1937717_8 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000004559 217.0
PYH1_k127_1937717_9 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000002793 195.0
PYH1_k127_1956229_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 337.0
PYH1_k127_1956229_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001801 265.0
PYH1_k127_1956229_2 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000005771 177.0
PYH1_k127_1956229_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000004158 100.0
PYH1_k127_1956229_4 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.000002281 53.0
PYH1_k127_1956229_5 Luciferase-like monooxygenase K14728 - - 0.0006633 47.0
PYH1_k127_196843_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 8.308e-214 684.0
PYH1_k127_196843_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 383.0
PYH1_k127_196843_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 356.0
PYH1_k127_196843_3 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 334.0
PYH1_k127_196843_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006767 263.0
PYH1_k127_196843_5 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000000000000019 222.0
PYH1_k127_196843_6 PFAM Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000711 75.0
PYH1_k127_199517_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 362.0
PYH1_k127_199517_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 340.0
PYH1_k127_199517_10 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000002934 148.0
PYH1_k127_199517_11 Psort location CytoplasmicMembrane, score K16923 - - 0.000000000000000000000000000000001495 136.0
PYH1_k127_199517_12 Cobalt transport protein K16785 - - 0.0000000000000000000000000001017 125.0
PYH1_k127_199517_13 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000002725 120.0
PYH1_k127_199517_14 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000001011 112.0
PYH1_k127_199517_15 COG1522 Transcriptional regulators - - - 0.00000000000000000000004341 107.0
PYH1_k127_199517_16 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000009795 102.0
PYH1_k127_199517_17 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000325 93.0
PYH1_k127_199517_18 membrane - - - 0.000000000003067 74.0
PYH1_k127_199517_19 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000002759 59.0
PYH1_k127_199517_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052,K11072 - 3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 298.0
PYH1_k127_199517_20 Bacterial extracellular solute-binding protein - - - 0.0000001906 63.0
PYH1_k127_199517_21 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.000001449 61.0
PYH1_k127_199517_22 Heavy-metal-associated domain K17686 GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 0.00001261 49.0
PYH1_k127_199517_23 - - - - 0.0000178 55.0
PYH1_k127_199517_3 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004001 275.0
PYH1_k127_199517_4 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002729 259.0
PYH1_k127_199517_5 ABC-type cobalt transport system ATPase component K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
PYH1_k127_199517_6 ATP-binding protein K16786 - - 0.0000000000000000000000000000000000000000000000000000000000000005173 230.0
PYH1_k127_199517_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000138 219.0
PYH1_k127_199517_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000001519 181.0
PYH1_k127_2061918_0 ATPase component of various ABC-type transport systems with duplicated ATPase domain K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 384.0
PYH1_k127_2061918_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 301.0
PYH1_k127_2061918_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000267 285.0
PYH1_k127_2061918_3 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000001199 251.0
PYH1_k127_2061918_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000678 199.0
PYH1_k127_2061918_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000006601 184.0
PYH1_k127_2061918_6 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000009428 78.0
PYH1_k127_2061918_7 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.0000000000001226 79.0
PYH1_k127_2061918_8 PFAM Cobalt transport protein K16785 - - 0.000000000103 72.0
PYH1_k127_2092595_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000001909 237.0
PYH1_k127_2092595_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000003478 190.0
PYH1_k127_2092595_2 Nitroreductase family - - - 0.000000000000000000000000000000000000009005 155.0
PYH1_k127_2092595_3 - - - - 0.000000000001423 71.0
PYH1_k127_227866_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 8.598e-209 662.0
PYH1_k127_227866_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
PYH1_k127_227866_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000007927 156.0
PYH1_k127_227866_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0008835 45.0
PYH1_k127_2286939_0 nUDIX hydrolase K01515,K01518,K01814 - 3.6.1.13,3.6.1.17,5.3.1.16 0.000000000000000000000000000000000004008 143.0
PYH1_k127_2286939_1 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000001768 147.0
PYH1_k127_2286939_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000001961 97.0
PYH1_k127_2286939_3 Phosphate transport regulator K07220 - - 0.000000000003326 77.0
PYH1_k127_2301938_0 ERCC4 domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 614.0
PYH1_k127_2301938_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000005152 234.0
PYH1_k127_2301938_2 DHHA1 domain K07463 - - 0.000000000000000001527 90.0
PYH1_k127_2341535_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.222e-211 664.0
PYH1_k127_2341535_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 353.0
PYH1_k127_2341535_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000009757 162.0
PYH1_k127_2341535_3 membrane K07149 - - 0.000000000000000000000000000000000000006486 156.0
PYH1_k127_2373488_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000001596 173.0
PYH1_k127_2373488_1 protein conserved in archaea - - - 0.00000000000000006885 91.0
PYH1_k127_2373488_2 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000004535 75.0
PYH1_k127_2460279_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 295.0
PYH1_k127_2460279_1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005637 246.0
PYH1_k127_2460279_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000002503 245.0
PYH1_k127_2460279_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004062 243.0
PYH1_k127_2460279_4 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000001043 222.0
PYH1_k127_2460279_5 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.000000000000000000001158 98.0
PYH1_k127_2460279_6 RNA binding K07581 - - 0.000000000002791 74.0
PYH1_k127_2460279_7 PFAM Major Facilitator Superfamily - - - 0.000000001126 70.0
PYH1_k127_2460279_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000006051 66.0
PYH1_k127_2460279_9 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00007813 49.0
PYH1_k127_2525176_0 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001506 275.0
PYH1_k127_2525176_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000001533 212.0
PYH1_k127_2525176_2 PFAM zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000002063 199.0
PYH1_k127_2525176_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000001265 159.0
PYH1_k127_2525176_4 - - - - 0.000000000000000000000000000000000000000913 165.0
PYH1_k127_2525176_5 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07005 - - 0.0000000000000000000003473 102.0
PYH1_k127_2525176_6 - - - - 0.00000000000001803 78.0
PYH1_k127_2525176_7 - - - - 0.000000000121 64.0
PYH1_k127_2525176_8 HNH nucleases - - - 0.00000000549 62.0
PYH1_k127_2525176_9 DNA methylase K07316 - 2.1.1.72 0.00009384 47.0
PYH1_k127_2571506_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
PYH1_k127_2571506_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000004395 203.0
PYH1_k127_2571506_2 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000114 203.0
PYH1_k127_2571506_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000002704 88.0
PYH1_k127_2571506_4 - - - - 0.000000000002818 69.0
PYH1_k127_2571506_5 - - - - 0.0000002191 54.0
PYH1_k127_2571506_6 - - - - 0.0000355 51.0
PYH1_k127_2571506_7 HNH nucleases - - - 0.00008661 46.0
PYH1_k127_2571561_0 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 326.0
PYH1_k127_2571561_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000002592 160.0
PYH1_k127_2571561_2 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.00000000000000000000000000000000000001414 149.0
PYH1_k127_2571561_3 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000001907 100.0
PYH1_k127_2571561_4 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.00000002203 57.0
PYH1_k127_2571561_5 GYD domain - - - 0.000001686 51.0
PYH1_k127_2615235_0 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 568.0
PYH1_k127_2615235_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 536.0
PYH1_k127_2615235_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 356.0
PYH1_k127_2615235_3 DNA binding protein K06930 - - 0.000000000000000000000000000000000000007382 155.0
PYH1_k127_2615244_0 saccharopine dehydrogenase activity - - - 0.000000000000000000000000000000002865 143.0
PYH1_k127_2615686_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.152e-257 816.0
PYH1_k127_2615686_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.888e-238 764.0
PYH1_k127_2615686_10 carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000004523 98.0
PYH1_k127_2615686_11 Universal stress protein - - - 0.0000000000000000002128 93.0
PYH1_k127_2615686_12 PFAM biotin lipoyl attachment domain-containing protein - - - 0.000000000000000005158 88.0
PYH1_k127_2615686_13 Mo-molybdopterin cofactor metabolic process K00366,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,2.7.7.80,2.8.1.11 0.000000628 56.0
PYH1_k127_2615686_2 Carboxyl transferase domain K19312 GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885 2.1.3.15,6.4.1.2,6.4.1.3 7.935e-203 643.0
PYH1_k127_2615686_3 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 396.0
PYH1_k127_2615686_4 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 372.0
PYH1_k127_2615686_5 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000005739 238.0
PYH1_k127_2615686_6 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000002951 241.0
PYH1_k127_2615686_7 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000007393 181.0
PYH1_k127_2615686_8 PFAM BioY family K03523 - - 0.00000000000000000000000000000000000000000002621 168.0
PYH1_k127_2615686_9 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000004442 146.0
PYH1_k127_2620234_0 Radical SAM domain protein K06937 - - 3.142e-218 689.0
PYH1_k127_2620234_1 Large family of predicted nucleotide-binding domains K06865 - - 2.398e-194 617.0
PYH1_k127_2620234_2 peptidase activity - - - 0.000000000000000000000000000000005507 134.0
PYH1_k127_2620234_3 Dodecin K09165 - - 0.00000000000000003544 83.0
PYH1_k127_2620234_4 PFAM thioesterase superfamily K07107 - - 0.0000000000000001981 84.0
PYH1_k127_262866_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 439.0
PYH1_k127_262866_1 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000001836 168.0
PYH1_k127_2683800_0 PFAM aconitate hydratase K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 590.0
PYH1_k127_2683800_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
PYH1_k127_2707713_0 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
PYH1_k127_2707713_1 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 403.0
PYH1_k127_2707713_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000007669 275.0
PYH1_k127_2707713_11 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 272.0
PYH1_k127_2707713_12 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000005958 265.0
PYH1_k127_2707713_13 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007789 259.0
PYH1_k127_2707713_14 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004585 254.0
PYH1_k127_2707713_15 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009014 243.0
PYH1_k127_2707713_16 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
PYH1_k127_2707713_17 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000009357 233.0
PYH1_k127_2707713_18 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000002943 219.0
PYH1_k127_2707713_19 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002664 201.0
PYH1_k127_2707713_2 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 397.0
PYH1_k127_2707713_20 Ser thr protein kinase K07176 - - 0.000000000000000000000000000000000000000000000000000000152 203.0
PYH1_k127_2707713_21 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000006967 200.0
PYH1_k127_2707713_22 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH1_k127_2707713_23 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000001336 192.0
PYH1_k127_2707713_24 methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000009649 190.0
PYH1_k127_2707713_25 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000768 180.0
PYH1_k127_2707713_26 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000000007608 174.0
PYH1_k127_2707713_27 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000085 171.0
PYH1_k127_2707713_28 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001061 174.0
PYH1_k127_2707713_29 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000001289 170.0
PYH1_k127_2707713_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 404.0
PYH1_k127_2707713_30 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000004072 146.0
PYH1_k127_2707713_31 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000001973 144.0
PYH1_k127_2707713_32 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000005464 141.0
PYH1_k127_2707713_33 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000306 129.0
PYH1_k127_2707713_34 membrane - - - 0.00000000000000000000000000000005315 136.0
PYH1_k127_2707713_35 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000002437 133.0
PYH1_k127_2707713_36 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000001947 132.0
PYH1_k127_2707713_37 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001726 117.0
PYH1_k127_2707713_38 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000003222 123.0
PYH1_k127_2707713_39 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000001113 117.0
PYH1_k127_2707713_4 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 360.0
PYH1_k127_2707713_40 ribosomal protein K02912 - - 0.00000000000000000000000006229 113.0
PYH1_k127_2707713_41 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005618 108.0
PYH1_k127_2707713_42 - - - - 0.0000000000000000000001312 102.0
PYH1_k127_2707713_43 Peptidase C13 family - - - 0.000000000000000000001299 110.0
PYH1_k127_2707713_44 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002283 98.0
PYH1_k127_2707713_45 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000003419 99.0
PYH1_k127_2707713_46 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002769 93.0
PYH1_k127_2707713_47 Belongs to the UPF0201 family K09736 - - 0.000000000000000001058 92.0
PYH1_k127_2707713_48 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000007688 88.0
PYH1_k127_2707713_49 DKCLD (NUC011) domain K03177,K11131 - 5.4.99.25 0.0000000000000000387 84.0
PYH1_k127_2707713_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
PYH1_k127_2707713_50 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000000001592 83.0
PYH1_k127_2707713_51 Glycosyltransferase family 87 - - - 0.0000000000000003022 91.0
PYH1_k127_2707713_52 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.0000000000000007126 89.0
PYH1_k127_2707713_53 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000007745 74.0
PYH1_k127_2707713_54 COG1522 Transcriptional regulators - - - 0.0000000000003451 73.0
PYH1_k127_2707713_55 Transcriptional regulator PadR-like family - - - 0.00000000000404 71.0
PYH1_k127_2707713_56 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001505 65.0
PYH1_k127_2707713_57 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000004458 64.0
PYH1_k127_2707713_58 Integral membrane protein DUF106 - - - 0.00000002113 62.0
PYH1_k127_2707713_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 312.0
PYH1_k127_2707713_7 Belongs to the peptidase M50B family - GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 307.0
PYH1_k127_2707713_8 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008051 279.0
PYH1_k127_2707713_9 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 270.0
PYH1_k127_2728256_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 542.0
PYH1_k127_2728256_1 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000001741 156.0
PYH1_k127_2728256_2 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000001229 147.0
PYH1_k127_2737081_0 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
PYH1_k127_2737081_1 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007485 280.0
PYH1_k127_2737081_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002167 273.0
PYH1_k127_2737081_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000009333 187.0
PYH1_k127_2737081_4 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000001818 175.0
PYH1_k127_2737081_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000005745 126.0
PYH1_k127_2743139_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 338.0
PYH1_k127_2743139_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000001689 145.0
PYH1_k127_2743139_2 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000555 132.0
PYH1_k127_2753227_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000009273 184.0
PYH1_k127_2753227_1 - - - - 0.000000000000000000000000000000000000002127 157.0
PYH1_k127_2753227_2 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000001267 58.0
PYH1_k127_2766647_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 577.0
PYH1_k127_2766647_1 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002149 229.0
PYH1_k127_2766647_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000001678 130.0
PYH1_k127_2766647_3 ribosomal protein K02976 - - 0.000000000000000000000000001307 114.0
PYH1_k127_2774783_0 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 612.0
PYH1_k127_2774783_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 409.0
PYH1_k127_2774783_10 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000001384 265.0
PYH1_k127_2774783_11 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000002617 248.0
PYH1_k127_2774783_12 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
PYH1_k127_2774783_13 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000004454 238.0
PYH1_k127_2774783_14 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000006229 194.0
PYH1_k127_2774783_15 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000002773 197.0
PYH1_k127_2774783_16 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K14084 - - 0.000000000000000000000000000000000000000000000000008542 188.0
PYH1_k127_2774783_17 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000002098 171.0
PYH1_k127_2774783_18 amino acid - - - 0.00000002049 64.0
PYH1_k127_2774783_19 PFAM Cupin - - - 0.00000009913 58.0
PYH1_k127_2774783_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 328.0
PYH1_k127_2774783_20 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005777,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006089,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009507,GO:0009526,GO:0009536,GO:0009628,GO:0009651,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0019863,GO:0019865,GO:0031967,GO:0031975,GO:0032787,GO:0042180,GO:0042182,GO:0042221,GO:0042579,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046185,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0051596,GO:0061727,GO:0071704,GO:0071944,GO:1901575,GO:1901615 4.4.1.5 0.0000002186 59.0
PYH1_k127_2774783_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 322.0
PYH1_k127_2774783_4 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 312.0
PYH1_k127_2774783_5 TIGRFAM 2-hydroxy-3-oxopropionate reductase K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 295.0
PYH1_k127_2774783_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 300.0
PYH1_k127_2774783_7 Enoyl-(Acyl carrier protein) reductase K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 291.0
PYH1_k127_2774783_8 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 290.0
PYH1_k127_2774783_9 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000004931 279.0
PYH1_k127_2791000_0 PFAM Amidohydrolase 3 K00200 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 611.0
PYH1_k127_2791000_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 323.0
PYH1_k127_2791000_2 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000003942 179.0
PYH1_k127_2791000_3 PFAM DNA polymerase, beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000003847 177.0
PYH1_k127_2791000_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000001073 146.0
PYH1_k127_2791000_5 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000007695 109.0
PYH1_k127_2791000_6 - - - - 0.0006581 50.0
PYH1_k127_2794849_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 603.0
PYH1_k127_2794849_1 Dihydroxyacetone kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 348.0
PYH1_k127_2794849_10 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000002384 148.0
PYH1_k127_2794849_11 ZPR1-related zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000002709 142.0
PYH1_k127_2794849_12 HIT domain K02503 - - 0.0000000000000000000000001152 111.0
PYH1_k127_2794849_13 - - - - 0.0000000000000000000004105 101.0
PYH1_k127_2794849_14 - K00960 - 2.7.7.6 0.00000000000000302 76.0
PYH1_k127_2794849_15 Sec61beta family - - - 0.00000001092 58.0
PYH1_k127_2794849_17 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000006696 52.0
PYH1_k127_2794849_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 336.0
PYH1_k127_2794849_3 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 295.0
PYH1_k127_2794849_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 303.0
PYH1_k127_2794849_5 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007338 278.0
PYH1_k127_2794849_6 - - - - 0.0000000000000000000000000000000000000000000000000000000286 203.0
PYH1_k127_2794849_7 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000001447 170.0
PYH1_k127_2794849_8 Dihydroxyacetone kinase K05879 - 2.7.1.121 0.0000000000000000000000000000000000000001079 158.0
PYH1_k127_2794849_9 ECF-type riboflavin transporter, S component - - - 0.0000000000000000000000000000000000004332 145.0
PYH1_k127_2801622_0 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 366.0
PYH1_k127_2801622_1 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 345.0
PYH1_k127_2801622_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000003506 213.0
PYH1_k127_2801622_3 COGs COG1175 ABC-type sugar transport systems permease components K02025 - - 0.000000000000000000000000000000000000000000000000000001275 202.0
PYH1_k127_2801622_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000007529 169.0
PYH1_k127_2801622_5 Bacterial extracellular solute-binding protein K02027,K10227 - - 0.0000001473 64.0
PYH1_k127_2801622_6 EamA-like transporter family - - - 0.0003401 51.0
PYH1_k127_2815459_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 455.0
PYH1_k127_2815459_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000001029 250.0
PYH1_k127_2815459_10 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000003294 55.0
PYH1_k127_2815459_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00004824 51.0
PYH1_k127_2815459_2 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000001961 194.0
PYH1_k127_2815459_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000001647 196.0
PYH1_k127_2815459_4 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000001277 185.0
PYH1_k127_2815459_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000004584 173.0
PYH1_k127_2815459_6 PFAM amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000003848 143.0
PYH1_k127_2815459_7 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000003342 127.0
PYH1_k127_2815459_8 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002069 117.0
PYH1_k127_2815459_9 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000007948 67.0
PYH1_k127_2893765_0 Sulfatase K01130 - 3.1.6.1 0.0 1020.0
PYH1_k127_2893765_1 COG2015 Alkyl sulfatase and related hydrolases - - - 2.218e-292 910.0
PYH1_k127_2893765_2 Involved in regulation of DNA replication K10725 - - 0.000000000000000000148 91.0
PYH1_k127_2893765_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000004151 85.0
PYH1_k127_2893765_5 SpoVT / AbrB like domain - - - 0.0007563 44.0
PYH1_k127_294439_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
PYH1_k127_294439_1 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 344.0
PYH1_k127_294439_11 Sec61beta family - - - 0.0000000489 56.0
PYH1_k127_294439_12 Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins. K06874 - - 0.00000006309 59.0
PYH1_k127_294439_13 Protein of unknown function (DUF2721) - - - 0.0001502 50.0
PYH1_k127_294439_2 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000101 218.0
PYH1_k127_294439_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000002274 164.0
PYH1_k127_294439_4 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000004398 147.0
PYH1_k127_294439_5 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000003452 126.0
PYH1_k127_294439_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.0000000000000000000002154 102.0
PYH1_k127_294439_7 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000004335 96.0
PYH1_k127_294439_8 Transcriptional regulator K11924 - - 0.0000000000000005093 84.0
PYH1_k127_294439_9 - - - - 0.000000000000001444 77.0
PYH1_k127_2993248_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 319.0
PYH1_k127_2993248_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000001415 200.0
PYH1_k127_2993248_2 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000001635 134.0
PYH1_k127_2993248_3 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000001808 93.0
PYH1_k127_2993248_5 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000001312 70.0
PYH1_k127_2993248_6 Maintenance of mitochondrial structure and function K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000001864 67.0
PYH1_k127_3000670_0 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 562.0
PYH1_k127_3000670_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 442.0
PYH1_k127_3000670_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 383.0
PYH1_k127_3000670_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 338.0
PYH1_k127_3000670_4 Belongs to the UPF0292 family - - - 0.000000000000005608 80.0
PYH1_k127_3023626_0 Glycolate oxidase subunit (GlcD) K00104,K21836 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0036094,GO:0043167,GO:0043168,GO:0047809,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.3.15,1.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 416.0
PYH1_k127_3023626_1 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
PYH1_k127_3023626_2 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000003794 175.0
PYH1_k127_3023626_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000007229 164.0
PYH1_k127_3023626_4 Polysaccharide deacetylase - - - 0.000000000000000000000001799 108.0
PYH1_k127_3023626_5 PAC2 family K07159 - - 0.00000000000000000003636 100.0
PYH1_k127_3057851_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 304.0
PYH1_k127_3057851_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000292 107.0
PYH1_k127_3145874_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.0 1061.0
PYH1_k127_3145874_1 CO dehydrogenase flavoprotein C-terminal domain - - - 6.091e-210 674.0
PYH1_k127_3145874_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000003128 251.0
PYH1_k127_3293545_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 390.0
PYH1_k127_3293545_1 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 377.0
PYH1_k127_3293545_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 366.0
PYH1_k127_3293545_3 acetamidase formamidase K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 288.0
PYH1_k127_3293545_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000005451 267.0
PYH1_k127_3293545_5 selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004734 248.0
PYH1_k127_3293545_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000004219 105.0
PYH1_k127_3293545_7 formylmethanofuran dehydrogenase, subunit E - - - 0.00000000000000001293 89.0
PYH1_k127_3316490_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 342.0
PYH1_k127_3316490_1 Glycosyl transferase, family 2 - - - 0.0001563 52.0
PYH1_k127_3381414_0 Protein of unknown function (DUF541) K09807 - - 0.000000005027 61.0
PYH1_k127_3381414_2 - - - - 0.00003834 49.0
PYH1_k127_3404350_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 494.0
PYH1_k127_3404350_1 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004268 259.0
PYH1_k127_3404350_10 thiolester hydrolase activity K00627,K06889 - 2.3.1.12 0.0000000000008078 72.0
PYH1_k127_3404350_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000006049 241.0
PYH1_k127_3404350_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000004251 223.0
PYH1_k127_3404350_4 - - - - 0.0000000000000000000000000000000000000000000000000000001925 202.0
PYH1_k127_3404350_5 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000007037 167.0
PYH1_k127_3404350_6 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000001069 134.0
PYH1_k127_3404350_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000001646 90.0
PYH1_k127_3404350_8 Domain of unknown function (DUF1893) - - - 0.00000000000008247 77.0
PYH1_k127_3404350_9 Membrane - - - 0.0000000000003316 71.0
PYH1_k127_3405561_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.136e-200 635.0
PYH1_k127_3405561_1 COG3335 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 507.0
PYH1_k127_3405561_2 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000000000000000000000000006162 224.0
PYH1_k127_3405561_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000002332 87.0
PYH1_k127_3420674_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 565.0
PYH1_k127_3420674_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 496.0
PYH1_k127_3420674_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001339 278.0
PYH1_k127_3420674_11 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005348 269.0
PYH1_k127_3420674_12 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009774 263.0
PYH1_k127_3420674_13 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000001191 246.0
PYH1_k127_3420674_14 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000001456 226.0
PYH1_k127_3420674_15 - - - - 0.00000000000000000000000000000000000000000000000002249 188.0
PYH1_k127_3420674_16 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000000000000000000000000000000000000004492 183.0
PYH1_k127_3420674_17 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000007786 136.0
PYH1_k127_3420674_18 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000000000000000007202 122.0
PYH1_k127_3420674_19 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000013 77.0
PYH1_k127_3420674_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 455.0
PYH1_k127_3420674_20 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000008988 73.0
PYH1_k127_3420674_3 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 419.0
PYH1_k127_3420674_4 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K10824,K12372,K13892 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 3.6.3.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 391.0
PYH1_k127_3420674_5 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 389.0
PYH1_k127_3420674_6 oligopeptide dipeptide ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 373.0
PYH1_k127_3420674_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 364.0
PYH1_k127_3420674_8 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
PYH1_k127_3420674_9 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 326.0
PYH1_k127_3423071_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 539.0
PYH1_k127_3423071_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 355.0
PYH1_k127_3423071_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001357 232.0
PYH1_k127_3423071_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000002628 180.0
PYH1_k127_3423071_4 amino acid-binding ACT domain protein K07103 - - 0.0000000000000000000000000000000000002777 147.0
PYH1_k127_3423071_5 Fructose-1-6-bisphosphatase, N-terminal domain K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.00000000000000000000000000000000007478 143.0
PYH1_k127_3423071_6 peptidase U32 - - - 0.00000000000000000006548 91.0
PYH1_k127_3423071_7 Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00002978 52.0
PYH1_k127_3430790_0 Double zinc ribbon - - - 0.0006758 48.0
PYH1_k127_3431732_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 588.0
PYH1_k127_3431732_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 434.0
PYH1_k127_3431732_10 Peptidase M28 - - - 0.00000000000000000000000000000000000000001255 172.0
PYH1_k127_3431732_11 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000883 158.0
PYH1_k127_3431732_12 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000009999 147.0
PYH1_k127_3431732_13 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000004039 109.0
PYH1_k127_3431732_14 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.0000002051 59.0
PYH1_k127_3431732_15 - - - - 0.00008333 51.0
PYH1_k127_3431732_2 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 308.0
PYH1_k127_3431732_3 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006897 261.0
PYH1_k127_3431732_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
PYH1_k127_3431732_5 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000005025 219.0
PYH1_k127_3431732_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000003439 206.0
PYH1_k127_3431732_7 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001784 199.0
PYH1_k127_3431732_8 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000001434 209.0
PYH1_k127_3431732_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000002727 204.0
PYH1_k127_3447130_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 370.0
PYH1_k127_3447130_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001045 256.0
PYH1_k127_3447130_2 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K00087,K03519 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000002349 216.0
PYH1_k127_3447130_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000456 177.0
PYH1_k127_3447130_4 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000464 136.0
PYH1_k127_3447130_5 PFAM thiamineS protein - - - 0.00055 46.0
PYH1_k127_3508456_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 320.0
PYH1_k127_3508456_1 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 305.0
PYH1_k127_3508456_2 Putative cyclase - - - 0.000000000000003707 84.0
PYH1_k127_3512726_0 aspartate racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 308.0
PYH1_k127_3512726_1 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000023 106.0
PYH1_k127_3553938_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000003643 200.0
PYH1_k127_3553938_1 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000001439 162.0
PYH1_k127_3553938_10 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000001898 84.0
PYH1_k127_3553938_11 Sap, sulfolipid-1-addressing protein - - - 0.00000001924 64.0
PYH1_k127_3553938_2 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000001064 163.0
PYH1_k127_3553938_3 PUA domain containing protein K07398 - - 0.00000000000000000000000000000000074 136.0
PYH1_k127_3553938_4 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000002249 116.0
PYH1_k127_3553938_5 - - - - 0.000000000000000000000000001436 115.0
PYH1_k127_3553938_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000001735 98.0
PYH1_k127_3553938_7 Peptidase C13 family - - - 0.000000000000000000008561 106.0
PYH1_k127_3553938_8 Uncharacterized protein conserved in archaea (DUF2110) - - - 0.000000000000000000009564 102.0
PYH1_k127_3553938_9 Transcriptional regulator K07332 - - 0.00000000000000000001897 100.0
PYH1_k127_3568334_0 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 309.0
PYH1_k127_3568334_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000001799 233.0
PYH1_k127_3568334_2 YHS domain K00441 - 1.12.98.1 0.00000000000000001708 88.0
PYH1_k127_3568740_0 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
PYH1_k127_3568740_1 MarR family - - - 0.000000000000000000000000000000000000000259 153.0
PYH1_k127_3568740_2 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000009404 106.0
PYH1_k127_3571427_0 PFAM YHS domain - - - 0.00000000001548 65.0
PYH1_k127_3571427_1 - - - - 0.0000003298 60.0
PYH1_k127_3571427_2 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000004411 55.0
PYH1_k127_3571427_3 Heavy-metal-associated domain K01533 - 3.6.3.4 0.000002807 51.0
PYH1_k127_3571427_4 transcription activator, effector binding - - - 0.0002926 46.0
PYH1_k127_3571982_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1306.0
PYH1_k127_3571982_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03006 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016591,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 9.444e-273 882.0
PYH1_k127_3571982_10 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 338.0
PYH1_k127_3571982_11 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
PYH1_k127_3571982_12 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 304.0
PYH1_k127_3571982_13 PFAM inner-membrane translocator K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 299.0
PYH1_k127_3571982_14 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003551 268.0
PYH1_k127_3571982_15 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000008198 236.0
PYH1_k127_3571982_16 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001369 254.0
PYH1_k127_3571982_17 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
PYH1_k127_3571982_18 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000116 215.0
PYH1_k127_3571982_19 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001655 210.0
PYH1_k127_3571982_2 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 529.0
PYH1_k127_3571982_20 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001003 195.0
PYH1_k127_3571982_21 - - - - 0.000000000000000000000000000000000000000000000000000003502 199.0
PYH1_k127_3571982_22 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000003025 196.0
PYH1_k127_3571982_23 - - - - 0.000000000000000000000000000000000000000000000000000649 194.0
PYH1_k127_3571982_24 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001999 192.0
PYH1_k127_3571982_25 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000005975 184.0
PYH1_k127_3571982_26 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000005027 147.0
PYH1_k127_3571982_27 amino acid - - - 0.00000000000000000000000000004997 131.0
PYH1_k127_3571982_28 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000003624 130.0
PYH1_k127_3571982_29 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000256 115.0
PYH1_k127_3571982_3 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 469.0
PYH1_k127_3571982_30 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000001799 112.0
PYH1_k127_3571982_31 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000000000006132 108.0
PYH1_k127_3571982_32 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000007737 96.0
PYH1_k127_3571982_33 DUF72 domain containing protein - - - 0.00000000000000002848 90.0
PYH1_k127_3571982_34 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000001976 91.0
PYH1_k127_3571982_35 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000007913 76.0
PYH1_k127_3571982_36 structural constituent of ribosome K02978 - - 0.0000000000003049 72.0
PYH1_k127_3571982_38 - - - - 0.0001368 47.0
PYH1_k127_3571982_4 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 472.0
PYH1_k127_3571982_5 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 408.0
PYH1_k127_3571982_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 390.0
PYH1_k127_3571982_7 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 362.0
PYH1_k127_3571982_8 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 355.0
PYH1_k127_3571982_9 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 360.0
PYH1_k127_3585500_0 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 497.0
PYH1_k127_3585500_1 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000006379 151.0
PYH1_k127_3605776_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 537.0
PYH1_k127_3605776_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000134 247.0
PYH1_k127_3605776_2 pyridoxamine 5-phosphate - - - 0.000000000000652 75.0
PYH1_k127_3605776_3 Staygreen protein - - - 0.0008326 44.0
PYH1_k127_3614245_0 Sulfate permease K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 470.0
PYH1_k127_3614245_1 Transposase - - - 0.00000000003309 74.0
PYH1_k127_3614245_2 Major facilitator superfamily - - - 0.0000001399 64.0
PYH1_k127_3614245_3 transposase IS116 IS110 IS902 family protein - - - 0.0000103 53.0
PYH1_k127_3674233_0 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 308.0
PYH1_k127_3674233_1 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000001443 259.0
PYH1_k127_3674233_2 Pfam:Methyltransf_6 - - - 0.0000000000000000000000000000000000000000000000000000001597 205.0
PYH1_k127_3674233_3 PFAM carbohydrate kinase K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.000000000000000000000000000000000000000000000000001476 202.0
PYH1_k127_3674233_4 Xylose isomerase-like TIM barrel K10709 - - 0.00000000000000000000000000000000000000000000006702 179.0
PYH1_k127_3674233_5 PFAM class II aldolase adducin family protein K01628,K03077 - 4.1.2.17,5.1.3.4 0.000000000000000000000000000000000000006607 154.0
PYH1_k127_3674233_6 Belongs to the UPF0173 family - - - 0.00000000000141 68.0
PYH1_k127_3674233_7 - - - - 0.0000000005131 65.0
PYH1_k127_3675352_0 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 438.0
PYH1_k127_3675352_1 Acts as a methyl group carrier between MtbB and MtbA K16179 - - 0.000000000000000000000000000000001165 134.0
PYH1_k127_3675352_2 - - - - 0.00000000000000000000000000005162 126.0
PYH1_k127_3689825_0 acetoacetate decarboxylase K01574 - 4.1.1.4 0.0000000000000000000000000000000000000003787 159.0
PYH1_k127_3689825_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000003306 151.0
PYH1_k127_3689825_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000009243 131.0
PYH1_k127_3689825_3 Transcriptional regulator K07729 - - 0.000000000000000000000002871 102.0
PYH1_k127_3689825_4 - - - - 0.00005834 50.0
PYH1_k127_374577_0 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441,K22174 - 1.1.98.4,1.12.98.1 0.00000000000000000000000000000000000000000000003765 185.0
PYH1_k127_374577_1 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000001591 110.0
PYH1_k127_374577_2 AIR synthase related protein domain protein K04655 - - 0.0000000007154 62.0
PYH1_k127_3762222_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003337 270.0
PYH1_k127_3762222_1 cellulose binding - - - 0.000000000000000001631 87.0
PYH1_k127_3762222_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000002108 79.0
PYH1_k127_3812115_0 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
PYH1_k127_3812115_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
PYH1_k127_3812115_2 ABC transporter (ATP-binding protein)-putative sodium extrusion ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
PYH1_k127_3812115_3 PFAM ABC-2 type transporter K09696 - - 0.000000000000000000000000000000000000000005579 169.0
PYH1_k127_3812115_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000183 146.0
PYH1_k127_3812115_5 DHHA1 domain K07463 - - 0.000000000000000000000000000000007513 141.0
PYH1_k127_389422_0 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000004864 146.0
PYH1_k127_389422_1 - - - - 0.0000000000000000000000004927 112.0
PYH1_k127_389422_2 CAAX protease self-immunity K07052 - - 0.0000000000000000001167 92.0
PYH1_k127_3928900_0 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 292.0
PYH1_k127_3928900_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000005909 54.0
PYH1_k127_3928900_2 Amino acid transporter - - - 0.00001286 55.0
PYH1_k127_3982328_0 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 297.0
PYH1_k127_3982328_1 Amino acid permease - - - 0.000000000000000000000000000000000000000003306 174.0
PYH1_k127_3982328_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510 - 1.1.98.2 0.000000000000000000000000000000000000000003428 162.0
PYH1_k127_3982328_3 - - - - 0.000000000000000000000000000000116 129.0
PYH1_k127_3988225_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 371.0
PYH1_k127_3988225_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 358.0
PYH1_k127_3988225_2 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
PYH1_k127_3988225_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
PYH1_k127_3988225_4 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003224 286.0
PYH1_k127_3988225_5 ATPases associated with a variety of cellular activities K10112,K17240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003278 268.0
PYH1_k127_3988225_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000000000000000000000000000002002 239.0
PYH1_k127_3988225_7 Protein of unknown function DUF47 K07220 - - 0.00000000007459 71.0
PYH1_k127_3988225_8 PFAM 4Fe-4S ferredoxin - - - 0.0003039 45.0
PYH1_k127_4047789_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.587e-237 748.0
PYH1_k127_4047789_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 8.827e-223 699.0
PYH1_k127_4047789_10 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 364.0
PYH1_k127_4047789_11 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 303.0
PYH1_k127_4047789_12 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 290.0
PYH1_k127_4047789_13 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000002009 217.0
PYH1_k127_4047789_14 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000009293 193.0
PYH1_k127_4047789_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000009248 160.0
PYH1_k127_4047789_16 Pfam:DUF385 - - - 0.0000000000000000000000000000000009139 133.0
PYH1_k127_4047789_17 Thiamine biosynthesis protein ThiJ K18199 - 4.2.1.103 0.0000000000000000000000000003869 122.0
PYH1_k127_4047789_18 COG1522 Transcriptional regulators - - - 0.00000000000000005005 82.0
PYH1_k127_4047789_19 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.0000000000000006957 84.0
PYH1_k127_4047789_2 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 4.888e-217 677.0
PYH1_k127_4047789_20 Staygreen protein - - - 0.0000006143 52.0
PYH1_k127_4047789_21 Dimerisation domain of Zinc Transporter - - - 0.00007871 53.0
PYH1_k127_4047789_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 5.359e-211 684.0
PYH1_k127_4047789_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 583.0
PYH1_k127_4047789_5 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 505.0
PYH1_k127_4047789_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 450.0
PYH1_k127_4047789_7 Coenzyme F420-reducing hydrogenase, gamma subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 396.0
PYH1_k127_4047789_8 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane K08265,K16887 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 392.0
PYH1_k127_4047789_9 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
PYH1_k127_4140972_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 502.0
PYH1_k127_4140972_1 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000007279 106.0
PYH1_k127_4141521_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000004535 214.0
PYH1_k127_4141521_1 PFAM homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000003577 91.0
PYH1_k127_4141521_2 Sugar (and other) transporter - - - 0.00000000000006515 80.0
PYH1_k127_4184557_0 AAA-like domain - - - 2.218e-267 848.0
PYH1_k127_4184557_1 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000000748 175.0
PYH1_k127_4184557_2 Peptidase family M48 - - - 0.0000000000000000003707 98.0
PYH1_k127_4184557_3 - - - - 0.000000000001769 74.0
PYH1_k127_4223371_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 406.0
PYH1_k127_4223371_1 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 356.0
PYH1_k127_4223371_10 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000002465 105.0
PYH1_k127_4223371_11 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000001313 89.0
PYH1_k127_4223371_2 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 339.0
PYH1_k127_4223371_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 342.0
PYH1_k127_4223371_4 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 325.0
PYH1_k127_4223371_5 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 309.0
PYH1_k127_4223371_6 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000003625 276.0
PYH1_k127_4223371_7 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000001369 192.0
PYH1_k127_4223371_8 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000002439 164.0
PYH1_k127_4223371_9 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000007298 151.0
PYH1_k127_4224848_0 kinase activity K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 567.0
PYH1_k127_4224848_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 331.0
PYH1_k127_4224848_2 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 323.0
PYH1_k127_4224848_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510,K21835 - 1.1.98.2,1.1.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 294.0
PYH1_k127_4224848_5 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000004784 229.0
PYH1_k127_4224848_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001185 100.0
PYH1_k127_4235337_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 589.0
PYH1_k127_4235337_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 496.0
PYH1_k127_4235337_10 - - - - 0.000000000000000000000000008052 116.0
PYH1_k127_4235337_12 Domain of unknown function (DUF4342) - - - 0.00000000000005626 76.0
PYH1_k127_4235337_13 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.0000000004742 69.0
PYH1_k127_4235337_14 Putative zinc- or iron-chelating domain - - - 0.0000000006438 64.0
PYH1_k127_4235337_15 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.00000000255 61.0
PYH1_k127_4235337_16 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22 0.000001794 59.0
PYH1_k127_4235337_17 - - - - 0.00004611 49.0
PYH1_k127_4235337_18 - - - - 0.0004618 50.0
PYH1_k127_4235337_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 391.0
PYH1_k127_4235337_3 SMART zinc finger, RanBP2-type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 377.0
PYH1_k127_4235337_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 333.0
PYH1_k127_4235337_5 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005926 287.0
PYH1_k127_4235337_6 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000006747 204.0
PYH1_k127_4235337_7 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000001433 168.0
PYH1_k127_4235337_8 VIT family - - - 0.000000000000000000000000000000000000003137 159.0
PYH1_k127_4235337_9 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000001062 127.0
PYH1_k127_4251993_0 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 293.0
PYH1_k127_4251993_1 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000002433 179.0
PYH1_k127_4251993_2 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000005507 153.0
PYH1_k127_4251993_3 Universal stress protein - - - 0.000000000000000006745 89.0
PYH1_k127_4251993_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000008132 77.0
PYH1_k127_4284121_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 337.0
PYH1_k127_4284121_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000008807 180.0
PYH1_k127_4284121_2 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000003311 95.0
PYH1_k127_4284121_3 Domain of unknown function (DUF1844) - - - 0.00000001108 62.0
PYH1_k127_4284121_4 DNA alkylation repair enzyme - - - 0.00000002521 64.0
PYH1_k127_4284121_5 FMN binding K03809 - 1.6.5.2 0.00000006332 60.0
PYH1_k127_4300366_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 360.0
PYH1_k127_4300366_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000001137 96.0
PYH1_k127_4310757_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002844 246.0
PYH1_k127_4310757_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000004524 210.0
PYH1_k127_4310757_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K19548 - 1.1.1.385 0.0000000000000000000000000000000000008232 143.0
PYH1_k127_4339595_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 580.0
PYH1_k127_4345341_0 Thi4 family K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 431.0
PYH1_k127_4345341_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000001295 216.0
PYH1_k127_4345341_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000002175 152.0
PYH1_k127_4345341_3 PFAM MOFRL domain protein K11529 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008887,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0071704,GO:1901564 2.7.1.165 0.00000000000000000000000000000000001573 138.0
PYH1_k127_4345341_4 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.000000000000000000000000001634 113.0
PYH1_k127_4345341_5 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000002108 79.0
PYH1_k127_4345341_6 HNH nucleases - - - 0.000003976 53.0
PYH1_k127_4345341_7 - - - - 0.00002357 51.0
PYH1_k127_4352472_0 DEAD DEAH box helicase domain protein K03724 - - 1.691e-246 793.0
PYH1_k127_4352472_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 489.0
PYH1_k127_4352472_2 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
PYH1_k127_4352472_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0001641 52.0
PYH1_k127_4370435_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1202.0
PYH1_k127_4370435_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 422.0
PYH1_k127_4370435_10 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000001884 130.0
PYH1_k127_4370435_11 - - - - 0.0000000000000000000000418 106.0
PYH1_k127_4370435_12 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000007784 104.0
PYH1_k127_4370435_13 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000000000008259 100.0
PYH1_k127_4370435_14 Leucyl aminopeptidase (Aminopeptidase t) K19689 - - 0.000000000000000005966 96.0
PYH1_k127_4370435_15 WD-40 repeat - - - 0.000002474 61.0
PYH1_k127_4370435_16 PRC-barrel domain - - - 0.00001376 51.0
PYH1_k127_4370435_17 - - - - 0.00005384 51.0
PYH1_k127_4370435_2 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
PYH1_k127_4370435_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004661 277.0
PYH1_k127_4370435_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001006 280.0
PYH1_k127_4370435_5 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002634 271.0
PYH1_k127_4370435_6 UV damage endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 252.0
PYH1_k127_4370435_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000001127 231.0
PYH1_k127_4370435_8 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000001055 219.0
PYH1_k127_4370435_9 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.000000000000000000000000000000000005328 139.0
PYH1_k127_4431910_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002731 274.0
PYH1_k127_4431910_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
PYH1_k127_4431910_2 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
PYH1_k127_4431910_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000004401 210.0
PYH1_k127_4431910_4 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000001139 87.0
PYH1_k127_4447381_0 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 482.0
PYH1_k127_4447381_1 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 474.0
PYH1_k127_4447381_10 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000302 164.0
PYH1_k127_4447381_11 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.000000000000000000000000000001715 133.0
PYH1_k127_4447381_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.000000000000000000000001262 105.0
PYH1_k127_4447381_13 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000182 96.0
PYH1_k127_4447381_14 Fibronectin type III domain K03933 - - 0.00000000000584 76.0
PYH1_k127_4447381_15 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000002525 68.0
PYH1_k127_4447381_2 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 377.0
PYH1_k127_4447381_3 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 380.0
PYH1_k127_4447381_4 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
PYH1_k127_4447381_5 Belongs to the RimK family K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000005235 227.0
PYH1_k127_4447381_6 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000003123 218.0
PYH1_k127_4447381_7 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000525 216.0
PYH1_k127_4447381_8 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000004513 162.0
PYH1_k127_4447381_9 F420-0:Gamma-glutamyl ligase - - - 0.00000000000000000000000000000000000000001864 164.0
PYH1_k127_4488684_0 peptide catabolic process K13722 - - 5.339e-241 767.0
PYH1_k127_4488684_1 P COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 382.0
PYH1_k127_4488684_2 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 323.0
PYH1_k127_4488684_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000004928 228.0
PYH1_k127_4488684_4 - - - - 0.000000000000000000000000000001019 132.0
PYH1_k127_4488684_5 signal transduction protein with CBS domains - - - 0.00000000000000000001379 98.0
PYH1_k127_4488684_7 peptidase K08303 - - 0.00001359 48.0
PYH1_k127_4513933_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 544.0
PYH1_k127_4513933_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000002384 216.0
PYH1_k127_4529456_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.669e-245 769.0
PYH1_k127_4529456_1 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000002608 274.0
PYH1_k127_4529456_2 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000001713 70.0
PYH1_k127_4529456_3 Beta-lactamase superfamily domain - - - 0.0001278 45.0
PYH1_k127_4540999_0 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 384.0
PYH1_k127_4540999_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 332.0
PYH1_k127_4540999_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000172 104.0
PYH1_k127_4540999_3 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0003328 44.0
PYH1_k127_4575783_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 7.797e-194 614.0
PYH1_k127_4575783_1 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 537.0
PYH1_k127_4575783_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000005535 171.0
PYH1_k127_4575783_11 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000006513 184.0
PYH1_k127_4575783_12 DNA polymerase Ligase (LigD) - - - 0.00000000000000000000000000000000000000000000145 167.0
PYH1_k127_4575783_13 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000006338 177.0
PYH1_k127_4575783_14 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000001642 140.0
PYH1_k127_4575783_15 - - - - 0.000000000000000000000000000001874 127.0
PYH1_k127_4575783_16 Flavodoxin - - - 0.00000000000000000003963 97.0
PYH1_k127_4575783_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000001183 64.0
PYH1_k127_4575783_18 - - - - 0.00000001334 62.0
PYH1_k127_4575783_19 Hsp20/alpha crystallin family K13993 - - 0.0000000987 60.0
PYH1_k127_4575783_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 485.0
PYH1_k127_4575783_3 small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
PYH1_k127_4575783_4 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 363.0
PYH1_k127_4575783_5 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 365.0
PYH1_k127_4575783_6 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 353.0
PYH1_k127_4575783_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
PYH1_k127_4575783_8 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 343.0
PYH1_k127_4575783_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000001043 246.0
PYH1_k127_4580436_0 PFAM beta-lactamase domain protein K07041 - - 4.024e-208 663.0
PYH1_k127_4580436_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 348.0
PYH1_k127_4580436_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000001332 223.0
PYH1_k127_4580436_3 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001983 186.0
PYH1_k127_4580436_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000001495 81.0
PYH1_k127_4667534_0 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001525 273.0
PYH1_k127_4686853_0 Aminopeptidase Iap family-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 443.0
PYH1_k127_4766420_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 296.0
PYH1_k127_4766420_1 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.0000000000000000000000000000000000000000000000000000000000000000001549 243.0
PYH1_k127_4766420_2 methyltransferase K07755 - 2.1.1.137 0.00000000000000002324 93.0
PYH1_k127_4797873_0 melibiose metabolic process K01222,K07406 - 3.2.1.22,3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 471.0
PYH1_k127_4797873_1 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000001345 256.0
PYH1_k127_4797873_10 - - - - 0.00000003208 59.0
PYH1_k127_4797873_11 glucosylceramidase activity - - - 0.0009772 47.0
PYH1_k127_4797873_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000002961 198.0
PYH1_k127_4797873_3 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000002498 166.0
PYH1_k127_4797873_4 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000001049 162.0
PYH1_k127_4797873_6 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000006228 135.0
PYH1_k127_4797873_8 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000003179 125.0
PYH1_k127_4797873_9 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000003213 108.0
PYH1_k127_4817510_0 PFAM Prolyl oligopeptidase family - - - 4.124e-271 848.0
PYH1_k127_4817510_1 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 426.0
PYH1_k127_4817510_2 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 314.0
PYH1_k127_4817510_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
PYH1_k127_4817510_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000003906 189.0
PYH1_k127_4817510_5 - - - - 0.00000000000000000000000000000000000000000000001693 184.0
PYH1_k127_4817510_6 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000002619 171.0
PYH1_k127_4817510_7 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000003871 166.0
PYH1_k127_4895104_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 8.202e-206 653.0
PYH1_k127_4895104_1 to SP P29212 GB L02649 GB X70994 PID 581070 GB U00096 percent identity K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 469.0
PYH1_k127_4895104_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 338.0
PYH1_k127_4895104_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000001275 180.0
PYH1_k127_4895104_4 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.0000000000000000000000000000000000000003012 156.0
PYH1_k127_4895104_5 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.000000000000000000000000000000000000132 148.0
PYH1_k127_4895104_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014,K03055 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000002593 79.0
PYH1_k127_4895104_7 - K02339 - 2.7.7.7 0.00000000000004552 81.0
PYH1_k127_4895104_8 - - - - 0.000285 48.0
PYH1_k127_4905431_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
PYH1_k127_4905431_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006472 258.0
PYH1_k127_4905431_2 glycosyl transferase family K01001 - 2.7.8.15 0.000000000000000000000000000000000000000000000000421 184.0
PYH1_k127_4905431_3 Trm112p-like protein - - - 0.0000000000000000000000005354 106.0
PYH1_k127_4905431_4 Protease prsW family - - - 0.000009455 53.0
PYH1_k127_4916597_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 372.0
PYH1_k127_4916597_1 PFAM Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000003332 182.0
PYH1_k127_4916597_2 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000496 60.0
PYH1_k127_49552_0 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000002593 161.0
PYH1_k127_507404_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
PYH1_k127_507404_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 364.0
PYH1_k127_507404_10 - - - - 0.0000000000000000000000000000000002137 145.0
PYH1_k127_507404_11 - - - - 0.0000000000000000000000001372 110.0
PYH1_k127_507404_12 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000195 89.0
PYH1_k127_507404_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000002719 80.0
PYH1_k127_507404_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 355.0
PYH1_k127_507404_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 299.0
PYH1_k127_507404_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 298.0
PYH1_k127_507404_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 292.0
PYH1_k127_507404_6 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 285.0
PYH1_k127_507404_7 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
PYH1_k127_507404_8 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000001382 185.0
PYH1_k127_507404_9 MFS_1 like family - - - 0.0000000000000000000000000000000000655 148.0
PYH1_k127_5075321_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 420.0
PYH1_k127_5075321_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000009928 199.0
PYH1_k127_5075321_2 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000002993 151.0
PYH1_k127_5075321_3 Conserved protein implicated in secretion - - - 0.000000000000000000000000000000007299 137.0
PYH1_k127_5075321_4 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000006394 121.0
PYH1_k127_5075321_5 Conserved protein implicated in secretion - - - 0.0000000000000000000000008666 112.0
PYH1_k127_5075321_6 - - - - 0.0000000000000000002157 97.0
PYH1_k127_5075321_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000003269 88.0
PYH1_k127_5075321_8 helix_turn_helix ASNC type - - - 0.00000000009958 71.0
PYH1_k127_5119854_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1045.0
PYH1_k127_5119854_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 354.0
PYH1_k127_5119854_2 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 324.0
PYH1_k127_5119854_3 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001608 205.0
PYH1_k127_5119854_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000183 162.0
PYH1_k127_5119854_5 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002244 160.0
PYH1_k127_5119854_6 Peptidase C13 family - - - 0.0000000005978 71.0
PYH1_k127_5143210_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 6.152e-213 677.0
PYH1_k127_5143210_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.679e-196 623.0
PYH1_k127_5143210_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000001505 150.0
PYH1_k127_5143210_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000007381 132.0
PYH1_k127_5143210_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000858 63.0
PYH1_k127_5143210_5 TIGRFAM MoaD family protein K03636 - - 0.0000000001507 66.0
PYH1_k127_5144005_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 368.0
PYH1_k127_5144005_1 - - - - 0.000000000000000000000000000000000000000001912 169.0
PYH1_k127_5194589_0 ERCC4 domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 417.0
PYH1_k127_5194589_1 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 407.0
PYH1_k127_5194589_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 318.0
PYH1_k127_5194589_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000001219 228.0
PYH1_k127_5194589_4 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
PYH1_k127_5194589_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000002676 174.0
PYH1_k127_5194589_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000001455 158.0
PYH1_k127_5194589_7 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000001247 129.0
PYH1_k127_5194589_9 KR domain - - - 0.00000000003329 65.0
PYH1_k127_5206715_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 428.0
PYH1_k127_5206715_1 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
PYH1_k127_5206715_2 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000005439 212.0
PYH1_k127_5206715_3 Subtilase family - - - 0.000000000000000004119 99.0
PYH1_k127_5206715_4 PFAM protein phosphatase 2C K01090 - 3.1.3.16 0.000004603 51.0
PYH1_k127_5206715_5 cAMP biosynthetic process K18672 - 2.7.7.85 0.0001173 54.0
PYH1_k127_5209202_0 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000000000000000000000000000000000000000000000000000000008276 216.0
PYH1_k127_5209202_1 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000000008243 179.0
PYH1_k127_5209202_2 - - - - 0.000000000000000001109 90.0
PYH1_k127_5245086_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1049.0
PYH1_k127_5245086_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 536.0
PYH1_k127_5245086_10 PFAM Metallophosphoesterase K03547 - - 0.000000000000001679 89.0
PYH1_k127_5245086_11 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00003019 51.0
PYH1_k127_5245086_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 337.0
PYH1_k127_5245086_4 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007427 240.0
PYH1_k127_5245086_5 AAA domain - - - 0.00000000000000000000000000000000000000000000000000003168 214.0
PYH1_k127_5245086_6 metal-dependent membrane protease K07052 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000005666 183.0
PYH1_k127_5245086_7 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000009527 177.0
PYH1_k127_5245086_8 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000003659 126.0
PYH1_k127_5245086_9 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000004259 89.0
PYH1_k127_5250465_0 arylsulfatase activity K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 580.0
PYH1_k127_5250465_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000002081 212.0
PYH1_k127_5250465_2 - K16924,K16928 - - 0.0000000000000000000000000000000000692 150.0
PYH1_k127_5259952_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 331.0
PYH1_k127_5259952_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000677 261.0
PYH1_k127_5267467_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.271e-196 633.0
PYH1_k127_5267467_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 378.0
PYH1_k127_5267467_2 Spore germination protein K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004229 291.0
PYH1_k127_5267467_3 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000001822 210.0
PYH1_k127_5267467_4 ABC transporter permease K19976 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000002694 128.0
PYH1_k127_5267467_5 - - - - 0.0000000000000000001463 94.0
PYH1_k127_5274875_0 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 329.0
PYH1_k127_5274875_1 NhaP-type Na H and K H K03316 - - 0.00000000000000000000000000000000000000000000000005207 192.0
PYH1_k127_5274875_2 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000002453 132.0
PYH1_k127_5274875_3 amino acid - - - 0.00000002334 61.0
PYH1_k127_5277101_0 Protein of unknown function (DUF917) K09703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 385.0
PYH1_k127_5277101_1 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 324.0
PYH1_k127_5277101_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 300.0
PYH1_k127_5277101_3 Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
PYH1_k127_5277101_4 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000002856 190.0
PYH1_k127_5277101_5 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000004646 80.0
PYH1_k127_5278285_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 7.381e-194 623.0
PYH1_k127_5278285_1 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 497.0
PYH1_k127_5278285_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002391 71.0
PYH1_k127_5278285_11 snRNP Sm proteins K04796 - - 0.000000000003366 69.0
PYH1_k127_5278285_12 - - - - 0.000000001336 62.0
PYH1_k127_5278285_13 Helix-turn-helix domain - - - 0.000008553 57.0
PYH1_k127_5278285_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 463.0
PYH1_k127_5278285_3 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 414.0
PYH1_k127_5278285_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
PYH1_k127_5278285_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000001476 231.0
PYH1_k127_5278285_6 Major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000000000000003378 159.0
PYH1_k127_5278285_7 major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000003202 131.0
PYH1_k127_5278285_8 - - - - 0.000000000000000000000573 101.0
PYH1_k127_5278285_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000006456 106.0
PYH1_k127_5280109_0 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 567.0
PYH1_k127_5280109_1 xylulokinase activity K11216 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009372,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0042710,GO:0044010,GO:0044237,GO:0044764,GO:0051704,GO:0071518 2.7.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 547.0
PYH1_k127_5280109_10 Transketolase, pyrimidine binding domain K21417 - - 0.0000001111 55.0
PYH1_k127_5280109_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 510.0
PYH1_k127_5280109_3 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 372.0
PYH1_k127_5280109_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
PYH1_k127_5280109_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005309 256.0
PYH1_k127_5280109_6 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.0000000000000000000000000000000001384 144.0
PYH1_k127_5280109_7 HAD-superfamily phosphatase, subfamily IIIC - - - 0.00000000000000000000000000000002809 134.0
PYH1_k127_5280109_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000004886 129.0
PYH1_k127_5280109_9 PFAM Major Facilitator Superfamily - - - 0.000000000004664 72.0
PYH1_k127_5355062_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 4.917e-220 700.0
PYH1_k127_5355062_1 in RNase L inhibitor, RLI K06174 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 616.0
PYH1_k127_5355062_10 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000001272 129.0
PYH1_k127_5355062_11 signal transduction protein with CBS domains - - - 0.000000000000000000000000000009395 123.0
PYH1_k127_5355062_12 TraB family - - - 0.00000000000000000000000001192 119.0
PYH1_k127_5355062_13 - - - - 0.00000000000000000000006807 105.0
PYH1_k127_5355062_14 - - - - 0.00000000000003301 74.0
PYH1_k127_5355062_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000002749 73.0
PYH1_k127_5355062_16 - - - - 0.00000005622 57.0
PYH1_k127_5355062_17 Domain of unknown function (DUF4443) - - - 0.000001075 57.0
PYH1_k127_5355062_18 archaeal coiled-coil protein - - - 0.000198 53.0
PYH1_k127_5355062_19 chromosome segregation and condensation protein ScpA K05896 - - 0.0007687 49.0
PYH1_k127_5355062_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 470.0
PYH1_k127_5355062_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 365.0
PYH1_k127_5355062_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 306.0
PYH1_k127_5355062_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000003758 246.0
PYH1_k127_5355062_6 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002356 242.0
PYH1_k127_5355062_7 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000007729 227.0
PYH1_k127_5355062_8 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000003414 214.0
PYH1_k127_5355062_9 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000002242 131.0
PYH1_k127_5378639_0 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 479.0
PYH1_k127_5378639_1 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 365.0
PYH1_k127_5378639_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 357.0
PYH1_k127_5378639_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 298.0
PYH1_k127_5378639_4 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003132 285.0
PYH1_k127_5378639_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
PYH1_k127_5386569_0 aldo keto reductase K18471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 415.0
PYH1_k127_5386569_1 Transketolase, central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 380.0
PYH1_k127_5386569_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 310.0
PYH1_k127_5386569_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009876 286.0
PYH1_k127_5386569_4 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000003052 250.0
PYH1_k127_5386569_5 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000003741 122.0
PYH1_k127_54794_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 334.0
PYH1_k127_54794_1 amino acid - - - 0.00000000000000000000000000001493 127.0
PYH1_k127_5490012_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 596.0
PYH1_k127_5490012_1 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 557.0
PYH1_k127_5490012_10 UbiA prenyltransferase family K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 299.0
PYH1_k127_5490012_11 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
PYH1_k127_5490012_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000706 278.0
PYH1_k127_5490012_13 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
PYH1_k127_5490012_14 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000116 233.0
PYH1_k127_5490012_15 Sap, sulfolipid-1-addressing protein - - - 0.00000000000000000000000000000000000000000000000000000028 201.0
PYH1_k127_5490012_16 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
PYH1_k127_5490012_17 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000001963 182.0
PYH1_k127_5490012_18 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000004231 186.0
PYH1_k127_5490012_19 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000000001569 176.0
PYH1_k127_5490012_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 531.0
PYH1_k127_5490012_20 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000144 153.0
PYH1_k127_5490012_21 - - - - 0.000000000000000000000000000000000000363 147.0
PYH1_k127_5490012_22 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000001815 150.0
PYH1_k127_5490012_23 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.000000000000000000000000000000004528 134.0
PYH1_k127_5490012_24 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000001459 138.0
PYH1_k127_5490012_25 VIT family - - - 0.00000000000000000000000000000002543 136.0
PYH1_k127_5490012_26 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.0000000000000000000000000000009434 123.0
PYH1_k127_5490012_27 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000003315 127.0
PYH1_k127_5490012_28 - - - - 0.00000000000000000000000000004399 126.0
PYH1_k127_5490012_29 PGAP1-like protein - - - 0.00000000000000000000004912 100.0
PYH1_k127_5490012_3 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 445.0
PYH1_k127_5490012_30 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000871 102.0
PYH1_k127_5490012_31 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.00000000000000000007464 92.0
PYH1_k127_5490012_32 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000001914 89.0
PYH1_k127_5490012_33 transporter K07238,K11021,K16267 - - 0.0000000000000002583 88.0
PYH1_k127_5490012_34 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.0000000000000004998 82.0
PYH1_k127_5490012_35 - - - - 0.0000000000001897 76.0
PYH1_k127_5490012_36 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.0000000000007908 73.0
PYH1_k127_5490012_37 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000005662 74.0
PYH1_k127_5490012_38 Domain of unknown function (DUF4382) - - - 0.0000007445 57.0
PYH1_k127_5490012_39 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000001545 57.0
PYH1_k127_5490012_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 442.0
PYH1_k127_5490012_40 - - - - 0.00005258 49.0
PYH1_k127_5490012_41 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00009724 54.0
PYH1_k127_5490012_5 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 420.0
PYH1_k127_5490012_6 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 412.0
PYH1_k127_5490012_7 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 393.0
PYH1_k127_5490012_8 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 362.0
PYH1_k127_5490012_9 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 345.0
PYH1_k127_5500315_0 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000001855 165.0
PYH1_k127_5500315_1 Universal stress protein - - - 0.0000000000000000002224 93.0
PYH1_k127_5500315_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000007344 64.0
PYH1_k127_5533940_0 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 353.0
PYH1_k127_5533940_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 313.0
PYH1_k127_5533940_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000002173 141.0
PYH1_k127_5533940_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000002471 119.0
PYH1_k127_5533940_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000008485 107.0
PYH1_k127_5541435_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.275e-263 836.0
PYH1_k127_5541435_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 506.0
PYH1_k127_5541435_10 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000007138 89.0
PYH1_k127_5541435_11 metalloendopeptidase activity - - - 0.000001522 55.0
PYH1_k127_5541435_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 470.0
PYH1_k127_5541435_3 GTPase of unknown function C-terminal K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 458.0
PYH1_k127_5541435_4 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 444.0
PYH1_k127_5541435_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 434.0
PYH1_k127_5541435_6 Protein of unknown function (DUF1512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 321.0
PYH1_k127_5541435_7 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000003139 240.0
PYH1_k127_5541435_8 Helix-turn-helix domain - - - 0.00000000000000000000000000000003608 132.0
PYH1_k127_5541435_9 CAAX protease self-immunity - - - 0.00000000000000000000169 108.0
PYH1_k127_5547437_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 321.0
PYH1_k127_5547437_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 302.0
PYH1_k127_5547437_2 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008769 279.0
PYH1_k127_5547437_3 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004987 248.0
PYH1_k127_5547437_4 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000006185 221.0
PYH1_k127_5547437_5 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000006527 186.0
PYH1_k127_5547437_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000004842 152.0
PYH1_k127_5547437_7 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000001056 85.0
PYH1_k127_5547437_8 DUF167 K09131 - - 0.0000001102 58.0
PYH1_k127_5547437_9 Transcriptional regulator K07722 - - 0.0001164 46.0
PYH1_k127_5588624_0 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001993 284.0
PYH1_k127_5588624_1 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000009559 265.0
PYH1_k127_5588624_2 - - - - 0.000000000000001184 81.0
PYH1_k127_5588624_3 - - - - 0.000004162 58.0
PYH1_k127_5606075_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.598e-197 623.0
PYH1_k127_5606075_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 428.0
PYH1_k127_5606075_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
PYH1_k127_5606075_3 Domain of unknown function (DUF4432) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001497 245.0
PYH1_k127_5606075_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000005967 132.0
PYH1_k127_5606075_5 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000003966 111.0
PYH1_k127_5606075_6 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000004452 56.0
PYH1_k127_5606075_7 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00002855 51.0
PYH1_k127_5606075_8 SCP-2 sterol transfer family - - - 0.0004861 48.0
PYH1_k127_5609674_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 456.0
PYH1_k127_5609674_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
PYH1_k127_5609674_10 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.0001491 49.0
PYH1_k127_5609674_11 serine threonine protein kinase K07178 - 2.7.11.1 0.0005123 43.0
PYH1_k127_5609674_2 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000003323 186.0
PYH1_k127_5609674_3 deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000004714 186.0
PYH1_k127_5609674_4 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000001441 179.0
PYH1_k127_5609674_5 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000000000000524 174.0
PYH1_k127_5609674_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000001506 141.0
PYH1_k127_5609674_7 Flavin reductase-like protein - - - 0.0000000000000000000000000000849 122.0
PYH1_k127_5609674_8 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000002706 129.0
PYH1_k127_5609674_9 Phospholipid methyltransferase - - - 0.00000002922 62.0
PYH1_k127_5671990_0 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000000000002498 166.0
PYH1_k127_5671990_1 Transcriptional regulator, TrmB - - - 0.00000000000000000000000003108 118.0
PYH1_k127_5671990_2 membrane protein domain - - - 0.000000000000000000001944 101.0
PYH1_k127_5675098_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000006033 178.0
PYH1_k127_5675098_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000005942 98.0
PYH1_k127_5679159_0 Biotin-protein ligase, N terminal - - - 0.000000000000000000000000000000000000000000004098 175.0
PYH1_k127_5679159_1 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000005094 122.0
PYH1_k127_5679159_2 PFAM CBS domain containing protein - - - 0.0000000000000000003849 91.0
PYH1_k127_5679159_3 Mut7-C ubiquitin - - - 0.000000005667 58.0
PYH1_k127_5858437_0 - - - - 0.000000000000000000000000000009213 130.0
PYH1_k127_5858437_1 - - - - 0.00000000000000000000000001036 123.0
PYH1_k127_5858437_2 GIY-YIG catalytic domain K07461 - - 0.00000000000000006382 83.0
PYH1_k127_5858437_3 PFAM Radical SAM domain protein - - - 0.0000000000001597 79.0
PYH1_k127_5858437_4 PEP-utilising enzyme, mobile domain - - - 0.00000000001036 70.0
PYH1_k127_5879556_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 3.149e-202 644.0
PYH1_k127_5919719_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 530.0
PYH1_k127_5919719_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 464.0
PYH1_k127_5919719_10 GHMP kinases C terminal K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
PYH1_k127_5919719_11 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
PYH1_k127_5919719_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000368 243.0
PYH1_k127_5919719_13 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
PYH1_k127_5919719_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000007687 207.0
PYH1_k127_5919719_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000003447 201.0
PYH1_k127_5919719_16 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001884 189.0
PYH1_k127_5919719_17 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000005135 188.0
PYH1_k127_5919719_18 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000001805 187.0
PYH1_k127_5919719_19 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000123 177.0
PYH1_k127_5919719_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 448.0
PYH1_k127_5919719_20 membrane K08979 - - 0.000000000000000000000000000000000000000000002012 186.0
PYH1_k127_5919719_21 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002498 162.0
PYH1_k127_5919719_22 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000004397 150.0
PYH1_k127_5919719_23 epimerase - - - 0.0000000000000000000000000000000000002964 143.0
PYH1_k127_5919719_24 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000001303 140.0
PYH1_k127_5919719_25 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000005165 145.0
PYH1_k127_5919719_26 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002664 124.0
PYH1_k127_5919719_27 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000004353 114.0
PYH1_k127_5919719_28 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000001007 110.0
PYH1_k127_5919719_29 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000005024 99.0
PYH1_k127_5919719_3 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 389.0
PYH1_k127_5919719_30 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.00000000000000000002575 94.0
PYH1_k127_5919719_31 Ferric reductase like transmembrane component - - - 0.000000000000000007908 96.0
PYH1_k127_5919719_32 AraC-like ligand binding domain - - - 0.000000000000005314 79.0
PYH1_k127_5919719_33 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.000000000001493 70.0
PYH1_k127_5919719_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000004342 71.0
PYH1_k127_5919719_35 Thiamine pyrophosphate enzyme, central domain K01652,K16787 - 2.2.1.6 0.00000000007037 64.0
PYH1_k127_5919719_36 AraC-like ligand binding domain - - - 0.000000000837 64.0
PYH1_k127_5919719_37 CBS domain - - - 0.000000001361 70.0
PYH1_k127_5919719_38 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000004155 54.0
PYH1_k127_5919719_4 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 385.0
PYH1_k127_5919719_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 362.0
PYH1_k127_5919719_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 332.0
PYH1_k127_5919719_7 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 324.0
PYH1_k127_5919719_8 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 308.0
PYH1_k127_5919719_9 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 295.0
PYH1_k127_5934412_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 333.0
PYH1_k127_5934412_1 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000007721 254.0
PYH1_k127_5934412_10 - - - - 0.0000000000000168 76.0
PYH1_k127_5934412_11 Domain of unknown function (DUF1508) K09946 - - 0.0000000000005972 70.0
PYH1_k127_5934412_12 Lipocalin-like domain - - - 0.0000000001461 66.0
PYH1_k127_5934412_13 Glycosyltransferase, group 2 family protein - - - 0.00001008 57.0
PYH1_k127_5934412_14 Lipocalin-like domain - - - 0.00001043 49.0
PYH1_k127_5934412_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000002099 211.0
PYH1_k127_5934412_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000002024 208.0
PYH1_k127_5934412_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000002449 205.0
PYH1_k127_5934412_5 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000002006 164.0
PYH1_k127_5934412_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000447 161.0
PYH1_k127_5934412_7 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000001597 157.0
PYH1_k127_5934412_8 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.00000000000000000000000000000001672 135.0
PYH1_k127_5934412_9 RNA-binding protein contains TRAM domain - - - 0.0000000000000000004713 88.0
PYH1_k127_5936818_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.946e-196 623.0
PYH1_k127_5936818_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.028e-195 627.0
PYH1_k127_5936818_10 PFAM Threonyl alanyl tRNA synthetase, SAD K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
PYH1_k127_5936818_11 ATPases associated with a variety of cellular activities K02017,K15497 - 3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000001333 234.0
PYH1_k127_5936818_12 cellular alkane metabolic process K16176 - 2.1.1.248 0.000000000000000000000000000000000000000000000000000000000001961 229.0
PYH1_k127_5936818_13 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000006011 218.0
PYH1_k127_5936818_14 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000006078 213.0
PYH1_k127_5936818_15 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000005194 202.0
PYH1_k127_5936818_16 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000158 181.0
PYH1_k127_5936818_17 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000003026 173.0
PYH1_k127_5936818_18 Sugar (and other) transporter - - - 0.0000000000000000000000001388 120.0
PYH1_k127_5936818_19 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000004363 77.0
PYH1_k127_5936818_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 578.0
PYH1_k127_5936818_20 Creatinase/Prolidase N-terminal domain - - - 0.0000000000004753 72.0
PYH1_k127_5936818_21 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000002625 74.0
PYH1_k127_5936818_22 pfam yhs - - - 0.000000000003181 70.0
PYH1_k127_5936818_23 Phosphoribosyl transferase domain - - - 0.000002641 51.0
PYH1_k127_5936818_24 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000008388 56.0
PYH1_k127_5936818_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 537.0
PYH1_k127_5936818_4 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 459.0
PYH1_k127_5936818_5 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 361.0
PYH1_k127_5936818_6 arginine decarboxylase activity K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000292 248.0
PYH1_k127_5936818_7 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000004171 239.0
PYH1_k127_5936818_8 Asp Glu hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000003266 228.0
PYH1_k127_5936818_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000001055 231.0
PYH1_k127_5959460_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.102e-232 732.0
PYH1_k127_5959460_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 587.0
PYH1_k127_5959460_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001335 289.0
PYH1_k127_5959460_11 Chorismate mutase type II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000008155 260.0
PYH1_k127_5959460_12 TIGRFAM Shikimate kinase K00891 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000003135 213.0
PYH1_k127_5959460_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000002605 177.0
PYH1_k127_5959460_14 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000002222 153.0
PYH1_k127_5959460_15 prephenate dehydrogenase K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.0000000000000000000000000003498 125.0
PYH1_k127_5959460_16 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000213 53.0
PYH1_k127_5959460_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 574.0
PYH1_k127_5959460_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 494.0
PYH1_k127_5959460_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 454.0
PYH1_k127_5959460_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 381.0
PYH1_k127_5959460_6 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 374.0
PYH1_k127_5959460_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 312.0
PYH1_k127_5959460_8 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 304.0
PYH1_k127_5959460_9 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006986 285.0
PYH1_k127_5968927_0 Psort location CytoplasmicMembrane, score 9.49 K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
PYH1_k127_5968927_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003841 252.0
PYH1_k127_5968927_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000001404 213.0
PYH1_k127_5968927_3 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000002047 174.0
PYH1_k127_5979993_0 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000000000000000000000000295 185.0
PYH1_k127_5979993_1 - - - - 0.00000000000000000000000000000000000000003833 156.0
PYH1_k127_5979993_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000001414 129.0
PYH1_k127_5979993_3 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000009184 107.0
PYH1_k127_5979993_4 Protein of unknown function (DUF1349) - - - 0.0002204 53.0
PYH1_k127_5983683_0 Homospermidine synthase K00808 - 2.5.1.44 5.888e-240 749.0
PYH1_k127_5983683_1 SMART zinc finger, RanBP2-type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 385.0
PYH1_k127_5983683_2 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007229 287.0
PYH1_k127_5983683_3 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
PYH1_k127_5983683_4 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000001211 160.0
PYH1_k127_5983683_5 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000327 152.0
PYH1_k127_5983683_6 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000001936 110.0
PYH1_k127_5983683_7 - - - - 0.0000000000000000000000003022 112.0
PYH1_k127_5983683_8 - - - - 0.000000000006337 75.0
PYH1_k127_5983683_9 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000007128 73.0
PYH1_k127_5986686_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 451.0
PYH1_k127_5986686_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 439.0
PYH1_k127_5986686_2 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 349.0
PYH1_k127_5986686_3 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
PYH1_k127_5986686_4 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004793 268.0
PYH1_k127_5986686_5 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000002323 184.0
PYH1_k127_5986686_6 Ribosome biogenesis protein, C-terminal K09140 - - 0.00000000000000000000000000000000000006442 150.0
PYH1_k127_5986686_7 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000009049 111.0
PYH1_k127_5986686_8 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.00000000001109 75.0
PYH1_k127_5993586_0 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000002443 188.0
PYH1_k127_5993586_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000003223 154.0
PYH1_k127_5993586_2 PFAM THUMP domain protein K06963 - - 0.000000000000000000000000000000000106 141.0
PYH1_k127_5993586_3 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000006746 67.0
PYH1_k127_6015081_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 321.0
PYH1_k127_6015081_1 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000006795 128.0
PYH1_k127_6015081_2 AsnC family K03718 - - 0.00000001399 66.0
PYH1_k127_6020335_0 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 335.0
PYH1_k127_6020335_1 - - - - 0.000000000001069 73.0
PYH1_k127_6020335_2 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.00003723 46.0
PYH1_k127_6024872_0 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 460.0
PYH1_k127_6024872_1 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001048 246.0
PYH1_k127_6024872_10 Psort location Cytoplasmic, score K09707 - - 0.00000000000000000000000000000000000005338 145.0
PYH1_k127_6024872_11 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000703 124.0
PYH1_k127_6024872_12 Formylmethanofuran dehydrogenase subunit D K00203 - 1.2.7.12 0.0000000000000000000000006509 108.0
PYH1_k127_6024872_13 - - - - 0.000000002015 68.0
PYH1_k127_6024872_14 Integron-associated effector binding protein - - - 0.000000008828 63.0
PYH1_k127_6024872_15 Belongs to the ParB family K03497 - - 0.000000295 61.0
PYH1_k127_6024872_16 - - - - 0.0000006753 60.0
PYH1_k127_6024872_17 Cupin - - - 0.000001146 57.0
PYH1_k127_6024872_2 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000006549 246.0
PYH1_k127_6024872_3 COGs COG1024 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
PYH1_k127_6024872_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
PYH1_k127_6024872_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000001024 204.0
PYH1_k127_6024872_6 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000009995 187.0
PYH1_k127_6024872_7 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000003808 181.0
PYH1_k127_6024872_8 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000000000000000000000009596 166.0
PYH1_k127_6024872_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000001305 158.0
PYH1_k127_6038866_0 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000182 270.0
PYH1_k127_6038866_1 Cytochrome b(N-terminal)/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000002163 195.0
PYH1_k127_6038866_2 - - - - 0.0000000000000000000000000000000000000000394 164.0
PYH1_k127_6038866_3 Rieske [2Fe-2S] domain K08355 - 1.20.2.1,1.20.9.1 0.00000000000000000000000003856 114.0
PYH1_k127_6038866_4 Cytochrome b subunit of the bc complex K00412,K15879 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000006354 110.0
PYH1_k127_6038866_5 - - - - 0.00000000000000001522 86.0
PYH1_k127_6079821_0 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 332.0
PYH1_k127_6079821_1 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
PYH1_k127_6079821_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000004584 193.0
PYH1_k127_6079821_3 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000007714 192.0
PYH1_k127_6079821_4 - K07149 - - 0.00000000000000000000000000000000000001128 153.0
PYH1_k127_6079821_5 Methyltransferase domain K06987 - - 0.000000000000000000000000000000002341 139.0
PYH1_k127_6079821_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000001988 101.0
PYH1_k127_6130136_0 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 451.0
PYH1_k127_6130136_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 310.0
PYH1_k127_6151226_0 DEAD DEAH box helicase domain protein K03724 - - 1.372e-201 661.0
PYH1_k127_6151226_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 373.0
PYH1_k127_6151226_10 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000001742 138.0
PYH1_k127_6151226_11 AAA domain K12614 GO:0000724,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0030915,GO:0032991,GO:0033554,GO:0033676,GO:0034641,GO:0035861,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050000,GO:0050896,GO:0051179,GO:0051304,GO:0051640,GO:0051641,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0090734,GO:0097159,GO:0097240,GO:0106068,GO:1901360,GO:1901363,GO:1902494,GO:1990234,GO:1990683 3.6.4.13 0.000000000000000001017 101.0
PYH1_k127_6151226_12 to Saccharomyces cerevisiae SMC5 (YOL034W) - GO:0000166,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022402,GO:0030554,GO:0030915,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051304,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0106068,GO:1901265,GO:1901360,GO:1901363,GO:1902494,GO:1990234 - 0.0000000000000006105 92.0
PYH1_k127_6151226_13 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.0000000000000103 79.0
PYH1_k127_6151226_14 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000696 55.0
PYH1_k127_6151226_15 H ACA RNA-protein complex K07569 - - 0.000001689 53.0
PYH1_k127_6151226_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 379.0
PYH1_k127_6151226_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 333.0
PYH1_k127_6151226_4 ABC-type cobalt transport system ATPase component K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002315 282.0
PYH1_k127_6151226_5 ATP-binding protein K16786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009806 255.0
PYH1_k127_6151226_6 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000001629 232.0
PYH1_k127_6151226_7 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000389 218.0
PYH1_k127_6151226_8 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000004001 188.0
PYH1_k127_6151226_9 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000001321 151.0
PYH1_k127_6173177_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 379.0
PYH1_k127_6173177_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
PYH1_k127_6173177_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
PYH1_k127_6173177_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000004171 179.0
PYH1_k127_6173177_4 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009181 126.0
PYH1_k127_6173177_5 - - - - 0.00007518 53.0
PYH1_k127_6173177_6 Lrp/AsnC ligand binding domain - - - 0.0002307 51.0
PYH1_k127_6173177_7 PRC-barrel domain protein - - - 0.0003224 51.0
PYH1_k127_6203833_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 454.0
PYH1_k127_6203833_1 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 304.0
PYH1_k127_6203833_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00003012 50.0
PYH1_k127_6219818_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 355.0
PYH1_k127_6219818_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002811 254.0
PYH1_k127_6219818_2 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000002964 207.0
PYH1_k127_6219818_3 transferase activity, transferring glycosyl groups - - - 0.000000001555 66.0
PYH1_k127_6221860_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 362.0
PYH1_k127_6221860_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000961 233.0
PYH1_k127_6221860_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000002113 208.0
PYH1_k127_6221860_3 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000132 188.0
PYH1_k127_6221860_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000001191 164.0
PYH1_k127_6221860_5 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.000000000000000000000000006856 122.0
PYH1_k127_6221860_6 PFAM Translin K07477 - - 0.00000000000000000000000002583 116.0
PYH1_k127_6221860_7 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.00000000000000000000000007794 115.0
PYH1_k127_6221860_8 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.000001625 53.0
PYH1_k127_6221860_9 Belongs to the UPF0248 family K09715 - - 0.0000168 51.0
PYH1_k127_6228365_0 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003058 273.0
PYH1_k127_6228365_1 peptidase - - - 0.000000000000000000000000000000000009334 145.0
PYH1_k127_6228365_2 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000005343 72.0
PYH1_k127_6228365_3 Short C-terminal domain K08982 - - 0.00003864 50.0
PYH1_k127_6243624_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 608.0
PYH1_k127_6243624_1 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 567.0
PYH1_k127_6243624_11 PFAM elongation factor Tu domain 2 - - - 0.000006327 51.0
PYH1_k127_6243624_2 Aconitase family (aconitate hydratase) K01703,K01705,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35,4.2.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 396.0
PYH1_k127_6243624_3 Polysulphide reductase K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006143 300.0
PYH1_k127_6243624_4 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 243.0
PYH1_k127_6243624_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000001476 176.0
PYH1_k127_6243624_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000002836 143.0
PYH1_k127_6243624_7 component of anaerobic dehydrogenases - - - 0.00000000000000000000000000226 121.0
PYH1_k127_6243624_8 4Fe-4S binding domain - - - 0.00000000000000004168 94.0
PYH1_k127_6243624_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000002093 80.0
PYH1_k127_6256951_0 isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 513.0
PYH1_k127_6256951_1 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 295.0
PYH1_k127_6257216_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002513 274.0
PYH1_k127_6257216_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000002734 154.0
PYH1_k127_6257216_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000002522 139.0
PYH1_k127_6260820_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 326.0
PYH1_k127_6260820_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002956 291.0
PYH1_k127_6260820_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003383 277.0
PYH1_k127_6260820_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000001162 178.0
PYH1_k127_6260820_4 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000001707 119.0
PYH1_k127_6260820_5 PFAM SNARE associated Golgi protein - - - 0.000000000000000000004533 100.0
PYH1_k127_6297467_0 Transketolase, central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 356.0
PYH1_k127_6297467_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 337.0
PYH1_k127_6297467_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 290.0
PYH1_k127_6297467_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000126 189.0
PYH1_k127_6297467_4 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000001732 174.0
PYH1_k127_6297467_5 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000001713 92.0
PYH1_k127_6297467_6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000001035 85.0
PYH1_k127_6307734_0 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 323.0
PYH1_k127_6307734_1 xylulokinase activity K00848,K00851,K00854 - 2.7.1.12,2.7.1.17,2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 320.0
PYH1_k127_6307734_2 - - - - 0.000000000000000000000000000000000000000000000000000015 198.0
PYH1_k127_6307734_3 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000001061 194.0
PYH1_k127_6307734_4 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000002713 199.0
PYH1_k127_6307734_5 amino acid - - - 0.0000000000000000000000000000000000000000000000002288 196.0
PYH1_k127_6344836_0 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000007953 133.0
PYH1_k127_6344836_1 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000166 108.0
PYH1_k127_6344836_2 - - - - 0.000000000000000000000001418 111.0
PYH1_k127_6344836_3 COG1522 Transcriptional regulators - - - 0.000000000000000000007513 96.0
PYH1_k127_6344836_4 Maintenance of mitochondrial structure and function K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000001097 64.0
PYH1_k127_6344836_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00005303 47.0
PYH1_k127_6363022_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 1.467e-223 730.0
PYH1_k127_6363022_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 601.0
PYH1_k127_6363022_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 419.0
PYH1_k127_6363022_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 380.0
PYH1_k127_6363022_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
PYH1_k127_6363022_5 GINS complex protein K09723 - - 0.0000000004355 67.0
PYH1_k127_6494360_0 - - - - 0.000000000000000000000000000000000000000001471 169.0
PYH1_k127_6494360_1 phosphatidylinositol metabolic process - - - 0.0000000000000000000000000009217 127.0
PYH1_k127_6494360_2 Parallel beta-helix repeats - - - 0.00000002136 67.0
PYH1_k127_6494360_3 - - - - 0.00002449 54.0
PYH1_k127_6611058_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000009198 232.0
PYH1_k127_6611058_1 PFAM NurA domain - - - 0.0000000000000000002249 100.0
PYH1_k127_6611058_3 COG0433 Predicted ATPase K06915 - - 0.0000000000000005197 82.0
PYH1_k127_6708857_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1039.0
PYH1_k127_6708857_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 488.0
PYH1_k127_6708857_10 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000002032 162.0
PYH1_k127_6708857_11 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.0000000000000000000000000000002564 128.0
PYH1_k127_6708857_12 PFAM Mov34 MPN PAD-1 family - - - 0.000000000000002292 82.0
PYH1_k127_6708857_13 - - - - 0.0000417 51.0
PYH1_k127_6708857_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 477.0
PYH1_k127_6708857_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 424.0
PYH1_k127_6708857_4 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 370.0
PYH1_k127_6708857_5 Belongs to the phosphohexose mutase family K22199 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 346.0
PYH1_k127_6708857_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 297.0
PYH1_k127_6708857_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000001637 219.0
PYH1_k127_6708857_8 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000006272 199.0
PYH1_k127_6708857_9 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.000000000000000000000000000000000000000000000001965 182.0
PYH1_k127_6710053_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K18020 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0043546,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363 1.2.5.3,1.2.99.8 5.554e-195 631.0
PYH1_k127_6710053_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000003268 257.0
PYH1_k127_6710053_10 spore germination - - - 0.000004657 58.0
PYH1_k127_6710053_2 photosystem I assembly BtpA K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000002197 232.0
PYH1_k127_6710053_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000002572 201.0
PYH1_k127_6710053_4 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000006479 184.0
PYH1_k127_6710053_5 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000334 164.0
PYH1_k127_6710053_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000001753 105.0
PYH1_k127_6710053_7 - - - - 0.00000000000000003571 89.0
PYH1_k127_6710053_8 Transporter, CPA2 family - - - 0.000000313 56.0
PYH1_k127_6710053_9 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000001383 55.0
PYH1_k127_6733272_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 366.0
PYH1_k127_6733272_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000819 276.0
PYH1_k127_6733272_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
PYH1_k127_6733272_3 coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000005376 96.0
PYH1_k127_6741308_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 318.0
PYH1_k127_6741308_1 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 293.0
PYH1_k127_6741308_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000119 263.0
PYH1_k127_6741308_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 244.0
PYH1_k127_6741308_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000005564 150.0
PYH1_k127_6741308_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000009159 77.0
PYH1_k127_6741308_6 SIS domain K02082 - - 0.00000000004488 68.0
PYH1_k127_6760273_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001626 272.0
PYH1_k127_6760273_1 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004463 254.0
PYH1_k127_6760273_10 Major facilitator superfamily - - - 0.000000002167 69.0
PYH1_k127_6760273_11 ABC-2 family transporter protein K01992 - - 0.00000006124 64.0
PYH1_k127_6760273_12 dipeptidase activity - - - 0.0003314 43.0
PYH1_k127_6760273_2 PFAM NmrA family protein - - - 0.000000000000000000000000000000000000000000000000000000000002571 214.0
PYH1_k127_6760273_3 spore germination K07790 - - 0.00000000000000000000000000000000000000000000000001634 192.0
PYH1_k127_6760273_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000969 176.0
PYH1_k127_6760273_5 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000006147 170.0
PYH1_k127_6760273_6 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.000000000000000000000000000000000000000000981 167.0
PYH1_k127_6760273_7 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000006062 153.0
PYH1_k127_6760273_8 extracellular matrix structural constituent - - - 0.00000000000000000000001475 115.0
PYH1_k127_6760273_9 PFAM ABC-2 type transporter K01992 - - 0.0000000000000001893 92.0
PYH1_k127_6766914_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000682 109.0
PYH1_k127_6793453_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.285e-204 652.0
PYH1_k127_6793453_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 445.0
PYH1_k127_6793453_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000001434 78.0
PYH1_k127_6793453_11 DNA polymerase beta domain protein region - - - 0.000000561 59.0
PYH1_k127_6793453_12 Probable zinc-ribbon domain - - - 0.000001984 53.0
PYH1_k127_6793453_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 410.0
PYH1_k127_6793453_3 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002208 228.0
PYH1_k127_6793453_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000006654 166.0
PYH1_k127_6793453_5 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000004118 162.0
PYH1_k127_6793453_6 Thiamine biosynthesis protein (ThiI) K06920 - 6.3.4.20 0.0000000000000000000000000000000000001183 150.0
PYH1_k127_6793453_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000003485 106.0
PYH1_k127_6793453_9 - - - - 0.00000000000000000007389 97.0
PYH1_k127_68522_0 alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 533.0
PYH1_k127_68522_1 - - - - 0.000000000000000000000000000000000000000000000000009014 190.0
PYH1_k127_68522_2 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000003072 130.0
PYH1_k127_68522_3 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000918 109.0
PYH1_k127_68522_4 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000001126 64.0
PYH1_k127_6889956_0 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000004311 211.0
PYH1_k127_6889956_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000007697 114.0
PYH1_k127_6889956_2 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000003741 114.0
PYH1_k127_6889956_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000003598 89.0
PYH1_k127_6889956_4 ubiquitin protein ligase activity K16276 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0032446,GO:0036211,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0051603,GO:0061630,GO:0061659,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0003365 45.0
PYH1_k127_6895940_0 PFAM Metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006204 276.0
PYH1_k127_6895940_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002539 256.0
PYH1_k127_6895940_2 amino acid - - - 0.00000000000000000000000000000000000000000000000444 192.0
PYH1_k127_6895940_3 - - - - 0.00000000000000000000000000000000000000000000002457 179.0
PYH1_k127_6895940_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000001042 119.0
PYH1_k127_6895940_5 Zinc finger domain - - - 0.0000002713 57.0
PYH1_k127_6895940_6 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0003695 46.0
PYH1_k127_6903791_0 DNA polymerase K02319 - 2.7.7.7 1.633e-242 777.0
PYH1_k127_6903791_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 590.0
PYH1_k127_6903791_10 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000001367 124.0
PYH1_k127_6903791_11 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000009925 115.0
PYH1_k127_6903791_12 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000002921 96.0
PYH1_k127_6903791_13 - K09143 - - 0.0000000000000000007769 90.0
PYH1_k127_6903791_14 PFAM CopG domain protein DNA-binding domain protein - - - 0.000000000002538 68.0
PYH1_k127_6903791_15 S25 ribosomal protein K02975 - - 0.00000001294 60.0
PYH1_k127_6903791_16 - - - - 0.000005058 57.0
PYH1_k127_6903791_17 Peptidase S8 K13277 - - 0.00001772 56.0
PYH1_k127_6903791_18 Domain of unknown function (DUF5050) - - - 0.0005068 49.0
PYH1_k127_6903791_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 551.0
PYH1_k127_6903791_3 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 475.0
PYH1_k127_6903791_4 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000006315 259.0
PYH1_k127_6903791_5 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002637 246.0
PYH1_k127_6903791_6 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000005231 221.0
PYH1_k127_6903791_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH1_k127_6903791_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000008831 194.0
PYH1_k127_6903791_9 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000001936 150.0
PYH1_k127_6939514_0 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 420.0
PYH1_k127_6939514_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 392.0
PYH1_k127_6939514_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
PYH1_k127_6939514_3 Alcohol dehydrogenase GroES domain protein K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000318 192.0
PYH1_k127_6939514_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000789 155.0
PYH1_k127_6939514_5 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000001882 143.0
PYH1_k127_6939514_6 PFAM galactose-1-phosphate uridyl transferase domain protein K00965 - 2.7.7.12 0.000000000001005 69.0
PYH1_k127_6974409_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 464.0
PYH1_k127_6974409_1 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000001629 70.0
PYH1_k127_6986868_0 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 353.0
PYH1_k127_6986868_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000002229 214.0
PYH1_k127_6986868_2 Hemerythrin HHE cation binding domain protein K09155 - - 0.00000000000000000000000005675 108.0
PYH1_k127_6986868_3 regulatory protein, arsR K03892 - - 0.00000000000000003243 87.0
PYH1_k127_7050382_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.0 1262.0
PYH1_k127_7050382_1 PFAM amino acid permease-associated region K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 559.0
PYH1_k127_7050382_10 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000002547 190.0
PYH1_k127_7050382_11 Domain of unknown function (DUF4872) - - - 0.0000000000000000000000000000000000000000000000000007953 197.0
PYH1_k127_7050382_12 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000178 208.0
PYH1_k127_7050382_13 pfkB family carbohydrate kinase - - - 0.00000000000000000000638 103.0
PYH1_k127_7050382_14 Putative tRNA binding domain - - - 0.000000000000008515 75.0
PYH1_k127_7050382_15 F420H(2)-dependent quinone reductase - - - 0.00000000000004325 83.0
PYH1_k127_7050382_16 PFAM Dak phosphatase K05879 - 2.7.1.121 0.00000000001157 74.0
PYH1_k127_7050382_17 Belongs to the UPF0200 family - - - 0.00000006263 54.0
PYH1_k127_7050382_18 AsnC family - - - 0.0002582 46.0
PYH1_k127_7050382_2 PFAM photosystem I assembly BtpA K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 377.0
PYH1_k127_7050382_3 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 383.0
PYH1_k127_7050382_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 372.0
PYH1_k127_7050382_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 338.0
PYH1_k127_7050382_6 Penicillin V acylase and related amidases K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 315.0
PYH1_k127_7050382_7 ABC-type transport system, involved in lipoprotein release, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001777 282.0
PYH1_k127_7050382_8 Oxidoreductase family, C-terminal alpha beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
PYH1_k127_7050382_9 PFAM ABC transporter K02003,K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
PYH1_k127_7153450_0 Heat shock 70 kDa protein K04043 - - 4.646e-226 716.0
PYH1_k127_7153450_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.889e-197 628.0
PYH1_k127_7153450_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 384.0
PYH1_k127_7153450_3 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000006948 222.0
PYH1_k127_7153450_4 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000000002014 179.0
PYH1_k127_7153450_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000003297 123.0
PYH1_k127_7153450_6 Excinuclease ABC, C subunit K10773 - 4.2.99.18 0.0000000000000004014 85.0
PYH1_k127_7273276_0 2-hydroxyglutaryl-CoA dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 351.0
PYH1_k127_7273276_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000009826 227.0
PYH1_k127_7273276_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000004819 216.0
PYH1_k127_7273276_3 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000003952 212.0
PYH1_k127_7273276_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000004747 113.0
PYH1_k127_7309073_0 VIT family - - - 0.000000000000000000000000000000000000000000005792 172.0
PYH1_k127_7309073_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000007101 123.0
PYH1_k127_7309073_2 this gene contains a nucleotide ambiguity which may be the result of a sequencing error K20276 - - 0.000000000000234 83.0
PYH1_k127_731355_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 371.0
PYH1_k127_731355_1 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 312.0
PYH1_k127_731355_2 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
PYH1_k127_731355_3 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000001719 180.0
PYH1_k127_731355_4 Thiamine transporter YuaJ K16789 - - 0.0000000000000000000000000000000000000000001431 166.0
PYH1_k127_731355_5 Radical SAM K04069 - 1.97.1.4 0.0000000000000002716 81.0
PYH1_k127_7369001_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0001023 50.0
PYH1_k127_7553857_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 8.955e-194 618.0
PYH1_k127_7553857_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 502.0
PYH1_k127_7553857_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
PYH1_k127_7553857_11 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000279 242.0
PYH1_k127_7553857_12 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000004612 219.0
PYH1_k127_7553857_13 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000001345 194.0
PYH1_k127_7553857_14 ABC-type transport system, periplasmic component surface lipoprotein K02058,K07335 - - 0.00000000000000000000000000000000000000000003354 176.0
PYH1_k127_7553857_15 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000002635 160.0
PYH1_k127_7553857_16 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000004067 147.0
PYH1_k127_7553857_17 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000001919 113.0
PYH1_k127_7553857_18 Universal stress protein - - - 0.000000000000000000000001799 108.0
PYH1_k127_7553857_19 ABC-2 type transporter - - - 0.00000000000000001202 93.0
PYH1_k127_7553857_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 502.0
PYH1_k127_7553857_20 glycolate biosynthetic process - - - 0.00000000000000003094 90.0
PYH1_k127_7553857_21 Transcriptional regulators - - - 0.0000000005655 69.0
PYH1_k127_7553857_3 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 482.0
PYH1_k127_7553857_4 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 418.0
PYH1_k127_7553857_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 412.0
PYH1_k127_7553857_6 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 367.0
PYH1_k127_7553857_7 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 361.0
PYH1_k127_7553857_8 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 364.0
PYH1_k127_7553857_9 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 336.0
PYH1_k127_7589268_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 9.037e-219 693.0
PYH1_k127_7589268_1 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 310.0
PYH1_k127_7589268_2 DUF72 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 236.0
PYH1_k127_7589268_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000002401 73.0
PYH1_k127_7589268_4 ThiS family K03636 - - 0.000007211 52.0
PYH1_k127_7589268_5 Limonene-1,2-epoxide hydrolase - - - 0.00001187 53.0
PYH1_k127_7657612_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 503.0
PYH1_k127_7657612_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 494.0
PYH1_k127_7657612_10 binds to the 23S rRNA K02921 - - 0.000000000000000000002119 99.0
PYH1_k127_7657612_11 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000403 82.0
PYH1_k127_7657612_12 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000003163 84.0
PYH1_k127_7657612_13 Fcf1 K07158 - - 0.0000000000000008313 82.0
PYH1_k127_7657612_14 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000008379 74.0
PYH1_k127_7657612_15 KEOPS complex Pcc1-like subunit K09741 - - 0.0006436 46.0
PYH1_k127_7657612_2 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 307.0
PYH1_k127_7657612_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 286.0
PYH1_k127_7657612_4 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000002932 221.0
PYH1_k127_7657612_5 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000003094 213.0
PYH1_k127_7657612_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000267 209.0
PYH1_k127_7657612_7 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000219 213.0
PYH1_k127_7657612_8 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000002466 198.0
PYH1_k127_7657612_9 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000006689 102.0
PYH1_k127_7708644_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 457.0
PYH1_k127_7708644_1 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000002462 166.0
PYH1_k127_7708644_2 Belongs to the UPF0273 family - - - 0.00000000000000000000000000008034 123.0
PYH1_k127_7716845_0 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 377.0
PYH1_k127_7716845_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 362.0
PYH1_k127_7716845_2 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008884 347.0
PYH1_k127_7716845_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 315.0
PYH1_k127_7716845_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003578 270.0
PYH1_k127_7716845_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000000000000000001203 123.0
PYH1_k127_7716845_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000002591 56.0
PYH1_k127_7729969_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.847e-200 646.0
PYH1_k127_7729969_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 598.0
PYH1_k127_7729969_2 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 306.0
PYH1_k127_7729969_3 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000002253 195.0
PYH1_k127_7729969_4 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000235 122.0
PYH1_k127_7729969_5 Subtilase family - - - 0.00000000003078 77.0
PYH1_k127_7729969_6 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000005807 70.0
PYH1_k127_7729969_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000002929 60.0
PYH1_k127_7729969_8 Protein of unknown function DUF47 K07220 - - 0.0007093 49.0
PYH1_k127_7735864_0 Psort location Cytoplasmic, score 8.87 K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 337.0
PYH1_k127_7735864_1 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 325.0
PYH1_k127_7735864_10 transferase activity, transferring glycosyl groups - - - 0.00000000007374 69.0
PYH1_k127_7735864_11 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000002662 59.0
PYH1_k127_7735864_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000002835 237.0
PYH1_k127_7735864_3 F420-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000001534 226.0
PYH1_k127_7735864_4 - - - - 0.000000000000000000000000000000000000000000000000008865 190.0
PYH1_k127_7735864_5 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000002958 126.0
PYH1_k127_7735864_6 PFAM Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000004587 132.0
PYH1_k127_7735864_7 cyclic nucleotide binding K09766,K10914 - - 0.000000000000000000000000224 110.0
PYH1_k127_7735864_8 - - - - 0.000000000000000000169 91.0
PYH1_k127_7735864_9 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.00000000000000008444 86.0
PYH1_k127_7785194_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 5.303e-209 663.0
PYH1_k127_7785194_1 Penicillin amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 494.0
PYH1_k127_7785194_10 Putative cyclase - - - 0.00000000000000005168 80.0
PYH1_k127_7785194_11 PFAM Transcription factor CBF NF-Y histone domain protein - - - 0.00000000000001273 76.0
PYH1_k127_7785194_12 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000005499 77.0
PYH1_k127_7785194_13 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.00000000001071 69.0
PYH1_k127_7785194_14 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.00000000002421 65.0
PYH1_k127_7785194_15 TIGRFAM MoaD family protein K03636 - - 0.00000001162 60.0
PYH1_k127_7785194_16 Thioredoxin K03671 - - 0.0000001767 58.0
PYH1_k127_7785194_17 - - - - 0.000003296 50.0
PYH1_k127_7785194_18 - - - - 0.0000168 55.0
PYH1_k127_7785194_2 actin actin family protein K18641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 443.0
PYH1_k127_7785194_3 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 395.0
PYH1_k127_7785194_4 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 382.0
PYH1_k127_7785194_5 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
PYH1_k127_7785194_6 PFAM ParB domain protein nuclease - - - 0.000000000000000000000000000000000000000356 162.0
PYH1_k127_7785194_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000001013 117.0
PYH1_k127_7785194_8 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000000006644 112.0
PYH1_k127_7785194_9 PFAM PAC2 family K06869 - - 0.0000000000000000000000001489 116.0
PYH1_k127_7794197_0 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000001482 226.0
PYH1_k127_7794197_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000006226 177.0
PYH1_k127_7794197_2 4Fe-4S binding domain - - - 0.000000000000000000000000001426 124.0
PYH1_k127_7800708_0 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001207 100.0
PYH1_k127_7800708_1 snRNP Sm proteins K04796 - - 0.00000000000000000000002575 101.0
PYH1_k127_7800708_2 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000001216 104.0
PYH1_k127_7800708_3 KH domain K07041 - - 0.000000000000000007816 85.0
PYH1_k127_7800708_4 Pfam:DUF552 K09152 - - 0.0000000000000005187 82.0
PYH1_k127_7821365_0 - - - - 0.000000000000000000000000000000000000000000005195 180.0
PYH1_k127_7821365_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000003139 154.0
PYH1_k127_7821365_2 Short-chain dehydrogenase reductase sdr K00034 - 1.1.1.47 0.000000000000004415 75.0
PYH1_k127_7821545_0 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000001633 144.0
PYH1_k127_7821545_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000001889 92.0
PYH1_k127_7821545_2 - - - - 0.0000009142 56.0
PYH1_k127_7856270_0 formate C-acetyltransferase glycine radical - - - 1.227e-225 724.0
PYH1_k127_7856270_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
PYH1_k127_7856270_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0004816 53.0
PYH1_k127_7856270_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
PYH1_k127_7856270_3 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009399 267.0
PYH1_k127_7856270_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000001883 186.0
PYH1_k127_7856270_5 phospholipase C - - - 0.00000000000000000000000000000000001797 156.0
PYH1_k127_7856270_6 protein secretion by the type IV secretion system - - - 0.000000000000000000000000000000001147 151.0
PYH1_k127_7856270_7 RNA-binding protein contains TRAM domain - - - 0.000000000000000003419 85.0
PYH1_k127_7856270_8 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.000000000000005948 84.0
PYH1_k127_791373_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 9.323e-203 641.0
PYH1_k127_791373_1 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 459.0
PYH1_k127_791373_2 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
PYH1_k127_791373_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004962 275.0
PYH1_k127_791373_4 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000009329 198.0
PYH1_k127_791373_5 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.00000000000000000000000000000000000003761 150.0
PYH1_k127_791373_6 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000001318 108.0
PYH1_k127_791373_7 Transglutaminase-like superfamily - - - 0.000000002234 66.0
PYH1_k127_8006927_0 Acetamidase formamidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
PYH1_k127_8006927_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004424 231.0
PYH1_k127_8006927_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000001003 218.0
PYH1_k127_8040652_0 Sap, sulfolipid-1-addressing protein - - - 0.00000000000000000000000000000000000000000000000000005651 194.0
PYH1_k127_8040652_1 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000003237 172.0
PYH1_k127_8040652_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000009486 152.0
PYH1_k127_8084498_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 362.0
PYH1_k127_8084498_1 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 301.0
PYH1_k127_8084498_10 Transcriptional regulator K07729 - - 0.000000000000000000006194 94.0
PYH1_k127_8084498_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000001269 85.0
PYH1_k127_8084498_12 Rubrerythrin - - - 0.0000000000000231 80.0
PYH1_k127_8084498_13 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000001097 66.0
PYH1_k127_8084498_14 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.00000002971 55.0
PYH1_k127_8084498_15 Bacterial transcription activator, effector binding domain - - - 0.00000006509 60.0
PYH1_k127_8084498_16 - - - - 0.0000003604 57.0
PYH1_k127_8084498_17 Putative adhesin - - - 0.00001739 54.0
PYH1_k127_8084498_18 Cupin - - - 0.00004165 46.0
PYH1_k127_8084498_19 Protein of unknown function (DUF3796) - - - 0.0001238 49.0
PYH1_k127_8084498_2 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009603 274.0
PYH1_k127_8084498_20 GH3 auxin-responsive promoter - - - 0.0004583 52.0
PYH1_k127_8084498_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
PYH1_k127_8084498_4 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000002715 207.0
PYH1_k127_8084498_5 - - - - 0.000000000000000000000000000000000000000000000000000002268 204.0
PYH1_k127_8084498_6 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000003309 190.0
PYH1_k127_8084498_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000465 139.0
PYH1_k127_8084498_8 - - - - 0.000000000000000000000000000086 122.0
PYH1_k127_8084498_9 PFAM regulatory protein TetR K03577,K18939 - - 0.0000000000000000000000008588 111.0
PYH1_k127_8104863_0 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000007366 224.0
PYH1_k127_8104863_1 ferredoxin-NADP+ reductase activity K00384 - 1.8.1.9 0.00000000000000000000000005751 117.0
PYH1_k127_8219063_0 PFAM hydrogenase formation HypD protein K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 451.0
PYH1_k127_8219063_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 362.0
PYH1_k127_8219063_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 348.0
PYH1_k127_8219063_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 307.0
PYH1_k127_8219063_4 Predicted Permease Membrane Region - - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
PYH1_k127_8219063_5 PFAM SpoVT AbrB - - - 0.000000000000000000000000000000000000000000004298 177.0
PYH1_k127_8219063_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000001753 99.0
PYH1_k127_8219063_7 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.0000000000000000000002925 103.0
PYH1_k127_8273575_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 444.0
PYH1_k127_8273575_1 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 422.0
PYH1_k127_8273575_2 Lrp/AsnC ligand binding domain - - - 0.00000000001655 67.0
PYH1_k127_8273575_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000002967 66.0
PYH1_k127_840086_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000002688 216.0
PYH1_k127_840086_1 Protein of unknown function (DUF998) - - - 0.0000008284 57.0
PYH1_k127_840086_2 CAAX protease self-immunity - - - 0.00003401 48.0
PYH1_k127_85872_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000002032 162.0
PYH1_k127_85872_1 TOBE domain K10112 - - 0.0000000000000004715 78.0
PYH1_k127_85872_2 EamA-like transporter family - - - 0.00000000000004719 83.0
PYH1_k127_860317_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.369e-248 798.0
PYH1_k127_860317_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 456.0
PYH1_k127_860317_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000003743 107.0
PYH1_k127_885867_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 418.0
PYH1_k127_885867_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 350.0
PYH1_k127_885867_2 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000003367 209.0
PYH1_k127_885867_3 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000002453 156.0
PYH1_k127_885867_4 Hydrolase, NUDIX family K01515 - 3.6.1.13 0.0000000000000000000000004427 108.0
PYH1_k127_885867_5 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000005575 112.0
PYH1_k127_893971_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 432.0
PYH1_k127_893971_1 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000001429 232.0
PYH1_k127_893971_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000004422 143.0
PYH1_k127_893971_3 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000003256 91.0
PYH1_k127_893971_4 HTH DNA binding domain - - - 0.00000001863 59.0
PYH1_k127_919158_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 407.0
PYH1_k127_919158_1 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
PYH1_k127_919158_10 PFAM Pyruvate K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000003678 183.0
PYH1_k127_919158_11 OsmC-like protein K04063 - - 0.000000000000002591 76.0
PYH1_k127_919158_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000131 78.0
PYH1_k127_919158_2 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
PYH1_k127_919158_3 ferredoxin oxidoreductase, subunit beta K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 335.0
PYH1_k127_919158_4 tripeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 318.0
PYH1_k127_919158_5 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001221 278.0
PYH1_k127_919158_6 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000001508 259.0
PYH1_k127_919158_7 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000001638 233.0
PYH1_k127_919158_8 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000001607 208.0
PYH1_k127_919158_9 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000002265 186.0
PYH1_k127_953727_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.994e-241 757.0
PYH1_k127_953727_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.053e-209 663.0
PYH1_k127_953727_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 383.0
PYH1_k127_953727_3 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
PYH1_k127_953727_4 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000001674 190.0
PYH1_k127_953727_5 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000001044 157.0
PYH1_k127_953727_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000002805 124.0
PYH1_k127_968506_0 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 524.0
PYH1_k127_968506_1 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 492.0
PYH1_k127_968506_10 OsmC-like protein - - - 0.0000000000000000000000000000000001087 138.0
PYH1_k127_968506_11 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000003336 124.0
PYH1_k127_968506_12 Methyltransferase domain K02493 - 2.1.1.297 0.00000000000000000000000000046 121.0
PYH1_k127_968506_13 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000001454 95.0
PYH1_k127_968506_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 389.0
PYH1_k127_968506_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 388.0
PYH1_k127_968506_4 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 387.0
PYH1_k127_968506_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 331.0
PYH1_k127_968506_6 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 329.0
PYH1_k127_968506_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002072 244.0
PYH1_k127_968506_8 radical SAM domain protein K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000002147 239.0
PYH1_k127_968506_9 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
PYH1_k127_996026_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
PYH1_k127_996026_1 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000001808 98.0
PYH1_k127_996026_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000005099 54.0
PYH1_k127_996026_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00009946 53.0