Overview

ID MAG03150
Name PYH1_bin.44
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family SM23-35
Genus DASPRG01
Species
Assembly information
Completeness (%) 64.04
Contamination (%) 2.05
GC content (%) 42.0
N50 (bp) 3,812
Genome size (bp) 1,232,668

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1361

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1000536_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
PYH1_k127_1000536_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000004177 236.0
PYH1_k127_1000536_2 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000001228 223.0
PYH1_k127_1000536_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000302 214.0
PYH1_k127_1000536_4 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000006234 211.0
PYH1_k127_1000536_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000001984 193.0
PYH1_k127_1000536_6 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.0000000000000000000000000000001731 130.0
PYH1_k127_1000536_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000001838 64.0
PYH1_k127_1003771_0 COG0058 Glucan phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 511.0
PYH1_k127_1003771_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 393.0
PYH1_k127_1003771_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 386.0
PYH1_k127_1003771_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 311.0
PYH1_k127_1040623_0 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000000000006287 198.0
PYH1_k127_1040623_1 - - - - 0.0000000004903 67.0
PYH1_k127_1042787_0 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 484.0
PYH1_k127_1042787_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 444.0
PYH1_k127_1042787_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 353.0
PYH1_k127_1042787_3 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 294.0
PYH1_k127_1042787_4 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000001776 238.0
PYH1_k127_1042787_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000007123 185.0
PYH1_k127_1042787_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000001974 140.0
PYH1_k127_1042787_7 DNA alkylation repair enzyme - - - 0.00000000000000000001535 91.0
PYH1_k127_1042787_8 DNA alkylation repair enzyme - - - 0.000000001379 60.0
PYH1_k127_1052586_0 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002687 297.0
PYH1_k127_1081610_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 327.0
PYH1_k127_1081610_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 319.0
PYH1_k127_1081610_2 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000002701 237.0
PYH1_k127_1083320_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.798e-252 782.0
PYH1_k127_1083320_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 352.0
PYH1_k127_1083320_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 288.0
PYH1_k127_1083320_3 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008736 253.0
PYH1_k127_1083320_4 Outer membrane efflux protein - - - 0.0000000000000000000000000001331 121.0
PYH1_k127_1089121_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
PYH1_k127_1089121_1 DUF167 K09131 - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 246.0
PYH1_k127_1089121_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000001564 151.0
PYH1_k127_1089121_3 RNA-binding protein containing a PIN domain K06962 - - 0.00000000000000000000000000000000000001414 149.0
PYH1_k127_1089121_4 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000000000933 141.0
PYH1_k127_1089121_5 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.00000001092 58.0
PYH1_k127_1093005_0 Helix-turn-helix domain of transposase family ISL3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 346.0
PYH1_k127_1093005_1 ABC 3 transport family K09816 - - 0.000316 44.0
PYH1_k127_1097385_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 354.0
PYH1_k127_1097385_1 HWE histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008806 254.0
PYH1_k127_1097385_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000468 197.0
PYH1_k127_1097385_3 Sulfurtransferase TusA - - - 0.00000000000001134 74.0
PYH1_k127_1103430_0 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 374.0
PYH1_k127_1103430_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000004407 222.0
PYH1_k127_1103430_2 RDD family - - - 0.000000000000000000000000006787 115.0
PYH1_k127_1136829_0 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007484 291.0
PYH1_k127_1136829_1 Domain of unknown function (DUF3943) - - - 0.00000000000005779 75.0
PYH1_k127_1136829_2 Multidrug transporter - - - 0.0000000000005289 74.0
PYH1_k127_1159506_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1210.0
PYH1_k127_1159506_1 HMGL-like K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 406.0
PYH1_k127_1159506_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004674 289.0
PYH1_k127_1159506_3 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000001202 165.0
PYH1_k127_1159506_4 AAA domain K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000003229 85.0
PYH1_k127_1164583_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 340.0
PYH1_k127_1164583_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000005772 224.0
PYH1_k127_1164583_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000008492 100.0
PYH1_k127_1170882_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 498.0
PYH1_k127_1170882_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000002375 121.0
PYH1_k127_1179017_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 378.0
PYH1_k127_1179017_1 HlyD family secretion protein K01993 - - 0.000007611 55.0
PYH1_k127_1209940_0 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000000000000000000000000000006958 192.0
PYH1_k127_1209940_1 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.00000000000000000000000000000000000000006649 165.0
PYH1_k127_1209940_2 Protein of unknown function (DUF521) K09123 - - 0.00000000001937 64.0
PYH1_k127_1219036_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 470.0
PYH1_k127_1219036_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000007434 221.0
PYH1_k127_1291649_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000001666 222.0
PYH1_k127_1291649_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000002732 178.0
PYH1_k127_1291649_2 Protein of unknown function (DUF2934) - - - 0.00000157 56.0
PYH1_k127_129276_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 521.0
PYH1_k127_129276_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 441.0
PYH1_k127_1299869_0 Transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003585 276.0
PYH1_k127_137546_0 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 495.0
PYH1_k127_137546_1 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 370.0
PYH1_k127_137546_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000004889 195.0
PYH1_k127_137546_3 - - - - 0.000000000000000000000000006519 119.0
PYH1_k127_1381288_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 337.0
PYH1_k127_1381288_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000001307 192.0
PYH1_k127_1381288_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000006379 139.0
PYH1_k127_140159_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.613e-202 644.0
PYH1_k127_140159_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 569.0
PYH1_k127_140159_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 507.0
PYH1_k127_140159_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 370.0
PYH1_k127_140159_4 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 291.0
PYH1_k127_140159_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
PYH1_k127_1429566_0 GTP-binding protein TypA K06207 - - 6.742e-216 680.0
PYH1_k127_1429566_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 589.0
PYH1_k127_1446548_0 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
PYH1_k127_1446548_1 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000009212 202.0
PYH1_k127_1446548_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000009893 159.0
PYH1_k127_1501344_0 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 309.0
PYH1_k127_1501344_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002693 270.0
PYH1_k127_1517429_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 335.0
PYH1_k127_1517429_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000003905 229.0
PYH1_k127_1517429_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000003836 204.0
PYH1_k127_1517429_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000002852 171.0
PYH1_k127_1517429_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000983 62.0
PYH1_k127_1517429_5 - - - - 0.0000001014 55.0
PYH1_k127_1529678_0 HTH-like domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 309.0
PYH1_k127_1529678_1 transposase activity K07483 - - 0.0000000000000000000000005885 107.0
PYH1_k127_1546200_0 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 375.0
PYH1_k127_1546200_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000002782 72.0
PYH1_k127_1567800_0 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000002666 172.0
PYH1_k127_1567800_1 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000216 131.0
PYH1_k127_1575606_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 317.0
PYH1_k127_1575606_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000001068 113.0
PYH1_k127_1595726_0 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 378.0
PYH1_k127_1595726_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 329.0
PYH1_k127_1602719_0 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001588 162.0
PYH1_k127_1602719_1 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000001693 148.0
PYH1_k127_1602719_2 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000009596 107.0
PYH1_k127_1602719_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000001933 101.0
PYH1_k127_1602719_4 PFAM Integrase core domain - - - 0.00000000001552 72.0
PYH1_k127_1602719_5 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.00005131 46.0
PYH1_k127_1605640_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 256.0
PYH1_k127_1605640_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002145 250.0
PYH1_k127_1605640_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000009559 98.0
PYH1_k127_1605640_3 radical SAM domain protein - - - 0.00002735 50.0
PYH1_k127_1605720_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000006548 174.0
PYH1_k127_1605720_1 - - - - 0.000005076 51.0
PYH1_k127_1613292_0 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000002621 186.0
PYH1_k127_1613292_1 Thiamine-binding protein - - - 0.0000000000000000000000000000000001123 134.0
PYH1_k127_1613292_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000006207 126.0
PYH1_k127_1613292_3 CBS domain K00974 - 2.7.7.72 0.0000000000000000000000001187 114.0
PYH1_k127_1613292_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000136 84.0
PYH1_k127_1635043_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000003385 162.0
PYH1_k127_1635043_1 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000003748 166.0
PYH1_k127_1635043_2 peroxiredoxin activity - - - 0.000000000000000000000000000000000000009791 151.0
PYH1_k127_1683067_0 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000008263 186.0
PYH1_k127_1683067_1 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000002349 160.0
PYH1_k127_1683067_2 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000003096 157.0
PYH1_k127_1683067_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000004027 111.0
PYH1_k127_1683067_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000278 89.0
PYH1_k127_1698661_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004043 286.0
PYH1_k127_1698661_1 transposase activity K07483 - - 0.0000002415 58.0
PYH1_k127_1709008_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 597.0
PYH1_k127_1709008_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
PYH1_k127_1709008_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
PYH1_k127_1709008_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000008247 213.0
PYH1_k127_1709008_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000232 189.0
PYH1_k127_1709008_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000002049 154.0
PYH1_k127_1709008_6 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000004857 112.0
PYH1_k127_1722970_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 314.0
PYH1_k127_1722970_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000003385 194.0
PYH1_k127_1722970_2 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000001006 130.0
PYH1_k127_1722970_3 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000009957 103.0
PYH1_k127_1725848_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 3.689e-209 656.0
PYH1_k127_1725848_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 454.0
PYH1_k127_1725848_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 421.0
PYH1_k127_1725848_3 Dehydrogenase E1 component K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 409.0
PYH1_k127_1725848_4 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 405.0
PYH1_k127_1725848_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 334.0
PYH1_k127_1725848_6 lactate metabolic process K11473,K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001856 257.0
PYH1_k127_1725848_7 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000546 210.0
PYH1_k127_1725848_9 Regulatory protein, FmdB family - - - 0.00000000000000002335 83.0
PYH1_k127_1729361_0 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
PYH1_k127_1729361_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001253 232.0
PYH1_k127_1729361_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000085 93.0
PYH1_k127_1734342_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 3.038e-259 820.0
PYH1_k127_1734342_1 alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000003248 52.0
PYH1_k127_1734342_2 Uncharacterised protein family (UPF0236) - - - 0.0000004548 53.0
PYH1_k127_1737449_0 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 313.0
PYH1_k127_1737449_1 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000821 188.0
PYH1_k127_1737449_2 Putative regulatory protein - - - 0.000000000000000000000001077 107.0
PYH1_k127_1764643_0 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 325.0
PYH1_k127_1764643_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 321.0
PYH1_k127_1764643_2 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000003258 252.0
PYH1_k127_1764643_3 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000001871 194.0
PYH1_k127_1781711_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.866e-217 694.0
PYH1_k127_1825760_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 370.0
PYH1_k127_1825760_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 312.0
PYH1_k127_1825760_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 267.0
PYH1_k127_1825760_3 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000004783 182.0
PYH1_k127_1825760_4 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000002566 145.0
PYH1_k127_1825760_5 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000184 94.0
PYH1_k127_184298_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 360.0
PYH1_k127_184298_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000008633 226.0
PYH1_k127_1845846_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000005584 168.0
PYH1_k127_1845846_1 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000004543 114.0
PYH1_k127_1889739_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 611.0
PYH1_k127_1889739_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 439.0
PYH1_k127_1889739_2 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 302.0
PYH1_k127_1889739_3 Alanine-zipper, major outer membrane lipoprotein - - - 0.00000000000001927 77.0
PYH1_k127_1912782_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 372.0
PYH1_k127_1912782_1 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000002485 95.0
PYH1_k127_1957717_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000001427 132.0
PYH1_k127_198027_0 Tetratricopeptide repeat - - - 0.0000000000001691 78.0
PYH1_k127_1985552_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 482.0
PYH1_k127_1985552_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000003263 229.0
PYH1_k127_1985552_2 DUF167 K09131 - - 0.000000000000000007451 85.0
PYH1_k127_1985552_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000004961 68.0
PYH1_k127_2030005_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1176.0
PYH1_k127_2042142_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 332.0
PYH1_k127_2042142_1 Tetratricopeptide repeats - - - 0.0009344 46.0
PYH1_k127_2051072_0 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 344.0
PYH1_k127_2051072_1 CopG antitoxin of type II toxin-antitoxin system - - - 0.000008774 50.0
PYH1_k127_2058793_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 3.402e-212 672.0
PYH1_k127_2058793_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001368 256.0
PYH1_k127_2058793_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000002584 216.0
PYH1_k127_2058793_3 membrane K00389 - - 0.000000000000000000000000000000000000000003453 160.0
PYH1_k127_2058793_4 Psort location Cytoplasmic, score - - - 0.00000000002265 64.0
PYH1_k127_2058793_5 Nucleotidyltransferase - - - 0.000001036 57.0
PYH1_k127_2065732_0 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 340.0
PYH1_k127_2065732_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000002673 192.0
PYH1_k127_207592_0 PFAM DRTGG domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 346.0
PYH1_k127_207592_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 302.0
PYH1_k127_207592_2 DNA-binding transcription factor activity - - - 0.0000000000000004381 83.0
PYH1_k127_207592_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000006418 51.0
PYH1_k127_2117853_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.669e-220 688.0
PYH1_k127_2117853_1 Protein of unknown function (DUF2934) - - - 0.0001157 50.0
PYH1_k127_2121494_0 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000000000000000000000000000000001904 212.0
PYH1_k127_2121494_1 Protein of unknown function (DUF2283) - - - 0.0000000000005695 70.0
PYH1_k127_2121494_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000002059 73.0
PYH1_k127_2121494_3 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000002462 69.0
PYH1_k127_2136802_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 462.0
PYH1_k127_2136802_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000003363 247.0
PYH1_k127_2136802_2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000008964 230.0
PYH1_k127_2136802_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000001394 165.0
PYH1_k127_2137968_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000009827 266.0
PYH1_k127_2137968_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000002918 213.0
PYH1_k127_2140826_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000007729 163.0
PYH1_k127_2140826_1 TonB C terminal - - - 0.0000000001207 73.0
PYH1_k127_2143135_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 291.0
PYH1_k127_2143135_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000001506 147.0
PYH1_k127_2143135_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000006349 127.0
PYH1_k127_2155867_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 298.0
PYH1_k127_2155867_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000006177 91.0
PYH1_k127_217184_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.683e-229 718.0
PYH1_k127_217184_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.445e-198 629.0
PYH1_k127_217184_10 PFAM Fimbrial assembly K02461 - - 0.0000000002217 73.0
PYH1_k127_217184_11 General secretion pathway protein M K02462 - - 0.0000000008855 67.0
PYH1_k127_217184_12 type IV pilus modification protein PilV K02458,K02671 - - 0.000000007846 63.0
PYH1_k127_217184_13 general secretion pathway protein K02457 - - 0.00000002436 61.0
PYH1_k127_217184_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000001604 54.0
PYH1_k127_217184_15 Fimbrial assembly protein (PilN) - - - 0.000000727 62.0
PYH1_k127_217184_2 type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 573.0
PYH1_k127_217184_3 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
PYH1_k127_217184_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 378.0
PYH1_k127_217184_5 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 362.0
PYH1_k127_217184_6 Bacterial type II and III secretion system protein K02453,K03219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 333.0
PYH1_k127_217184_7 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000001108 195.0
PYH1_k127_217184_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000002465 146.0
PYH1_k127_217184_9 pilus assembly protein PilW K02459 - - 0.000000000043 71.0
PYH1_k127_2177206_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 295.0
PYH1_k127_2177206_1 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000007507 218.0
PYH1_k127_2177206_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000007301 164.0
PYH1_k127_2177206_3 - - - - 0.00000000000000000000005125 102.0
PYH1_k127_2185971_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 451.0
PYH1_k127_2185971_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000005885 224.0
PYH1_k127_2185971_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000005351 199.0
PYH1_k127_2185971_3 PFAM GAF domain - - - 0.0000000000000000000000000000000000000000000004444 180.0
PYH1_k127_2185971_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000006926 68.0
PYH1_k127_218864_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 5.947e-212 664.0
PYH1_k127_218864_1 beta-lactamase - - - 0.000000000000000000000000002139 113.0
PYH1_k127_2200563_0 trisaccharide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 499.0
PYH1_k127_2200563_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000004747 172.0
PYH1_k127_2207897_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
PYH1_k127_2207897_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000008418 255.0
PYH1_k127_2207897_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000006358 233.0
PYH1_k127_2207897_3 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000004097 225.0
PYH1_k127_2207897_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000003502 218.0
PYH1_k127_2207897_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000001181 111.0
PYH1_k127_2221307_0 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 355.0
PYH1_k127_2221307_1 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000005067 150.0
PYH1_k127_2221307_2 TadE-like protein - - - 0.00002568 49.0
PYH1_k127_2224145_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 529.0
PYH1_k127_2224145_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 327.0
PYH1_k127_2224145_2 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000152 279.0
PYH1_k127_2224145_3 YbbR-like protein - - - 0.00000000000000000000000000000000000000001297 161.0
PYH1_k127_2267465_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 326.0
PYH1_k127_2267465_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000003438 171.0
PYH1_k127_2267465_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000531 147.0
PYH1_k127_2285086_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 553.0
PYH1_k127_2285086_1 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 510.0
PYH1_k127_2285086_2 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 308.0
PYH1_k127_2285086_3 PFAM ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002764 244.0
PYH1_k127_2361657_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1063.0
PYH1_k127_2361657_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000004777 144.0
PYH1_k127_2361657_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000002421 135.0
PYH1_k127_2362525_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 557.0
PYH1_k127_2362525_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 372.0
PYH1_k127_2362525_2 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001464 272.0
PYH1_k127_2362525_3 Glycosyl hydrolase family 3 N terminal domain - - - 0.00000001611 64.0
PYH1_k127_2377300_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009544 263.0
PYH1_k127_2377300_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000004213 166.0
PYH1_k127_2377300_2 RNase_H superfamily K07502 - - 0.0000000000000000000000001817 108.0
PYH1_k127_2387531_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 590.0
PYH1_k127_2387531_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 398.0
PYH1_k127_2387531_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
PYH1_k127_2387531_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000003255 69.0
PYH1_k127_2395393_0 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008158 273.0
PYH1_k127_2395393_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000278 252.0
PYH1_k127_2395393_2 translation initiation factor activity K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000003733 226.0
PYH1_k127_2395393_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000001529 211.0
PYH1_k127_2415606_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 308.0
PYH1_k127_2415606_1 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 313.0
PYH1_k127_245411_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 582.0
PYH1_k127_245411_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000001019 226.0
PYH1_k127_245411_2 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000001666 134.0
PYH1_k127_245411_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000004539 94.0
PYH1_k127_245411_4 helicase K06877 - - 0.0000000000004662 70.0
PYH1_k127_2505138_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 355.0
PYH1_k127_2505138_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
PYH1_k127_2505138_2 Spore Coat Protein U domain - - - 0.000007146 49.0
PYH1_k127_2505138_3 AAA domain K02450 - - 0.00001023 57.0
PYH1_k127_2519502_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 448.0
PYH1_k127_2519502_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
PYH1_k127_2519502_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000001234 73.0
PYH1_k127_254337_0 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000002047 216.0
PYH1_k127_254337_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000006193 182.0
PYH1_k127_254337_2 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000000003804 121.0
PYH1_k127_254337_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000001875 64.0
PYH1_k127_2571658_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 476.0
PYH1_k127_2571658_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000634 155.0
PYH1_k127_2571658_2 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000344 93.0
PYH1_k127_2571658_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000006814 60.0
PYH1_k127_2571658_4 RecX family - - - 0.0009359 48.0
PYH1_k127_2578452_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.471e-243 764.0
PYH1_k127_2578452_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
PYH1_k127_2578452_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 380.0
PYH1_k127_2578452_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000879 265.0
PYH1_k127_2578452_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
PYH1_k127_2578452_5 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
PYH1_k127_2578452_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000002395 193.0
PYH1_k127_2578452_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000003384 120.0
PYH1_k127_2578452_8 - - - - 0.00000000000000001459 86.0
PYH1_k127_2607908_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1042.0
PYH1_k127_2607908_1 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 292.0
PYH1_k127_2607908_2 InterPro IPR007367 - - - 0.00000000000000000000000000000000000000000000000000000000000006232 216.0
PYH1_k127_2607908_3 - - - - 0.0000000000000000000000000000000000000000000001158 170.0
PYH1_k127_2607908_4 Cation transport protein K03498 - - 0.000000000000000000000000000000000001796 141.0
PYH1_k127_2607908_5 DNA-binding transcription factor activity K03655 - 3.6.4.12 0.000000000000000000000000000000001503 132.0
PYH1_k127_2607908_6 - - - - 0.00000000000000000000000000000002802 128.0
PYH1_k127_2607908_7 - - - - 0.00000000000000000000000000000004077 132.0
PYH1_k127_2607908_8 Protein of unknown function DUF86 - - - 0.00000000000000000000000003128 114.0
PYH1_k127_2607908_9 Nucleotidyltransferase domain K07076 - - 0.00000000000004535 79.0
PYH1_k127_2619481_0 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 480.0
PYH1_k127_2619481_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
PYH1_k127_2619481_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 283.0
PYH1_k127_2695247_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 498.0
PYH1_k127_2695247_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 409.0
PYH1_k127_2695247_2 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 308.0
PYH1_k127_2695247_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001832 256.0
PYH1_k127_2695247_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000004331 239.0
PYH1_k127_2695247_5 deoxyribonuclease V activity K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000167 226.0
PYH1_k127_2695247_6 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000008315 132.0
PYH1_k127_2695247_7 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000006009 96.0
PYH1_k127_2695247_8 membrane protein domain - - - 0.000000000000000004246 98.0
PYH1_k127_270031_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 314.0
PYH1_k127_270031_1 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000008672 190.0
PYH1_k127_270031_2 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000109 189.0
PYH1_k127_270031_3 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000001581 156.0
PYH1_k127_270031_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.00000000001096 68.0
PYH1_k127_270031_5 - - - - 0.000000784 53.0
PYH1_k127_2725049_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000002941 231.0
PYH1_k127_2725049_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000003436 209.0
PYH1_k127_2725049_2 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000001001 132.0
PYH1_k127_2725049_3 isochorismatase - - - 0.0000000000000000000000000002863 115.0
PYH1_k127_2737166_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 365.0
PYH1_k127_2737166_1 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 319.0
PYH1_k127_2737166_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000009705 123.0
PYH1_k127_2737166_3 Pilus assembly protein, PilP K02665 - - 0.000000000001218 74.0
PYH1_k127_2737166_4 assembly protein PilN K02663 - - 0.00000001528 63.0
PYH1_k127_2738583_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.289e-227 709.0
PYH1_k127_2738583_1 lyase activity - - - 0.0000000000000000000000000000000002383 138.0
PYH1_k127_2741207_0 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 313.0
PYH1_k127_2741207_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 291.0
PYH1_k127_2741207_2 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000000000005341 225.0
PYH1_k127_2741207_3 acr, cog1430 K09005 - - 0.00000000000000000000000000009766 117.0
PYH1_k127_2750640_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.562e-233 738.0
PYH1_k127_2750640_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 447.0
PYH1_k127_2750640_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 321.0
PYH1_k127_2750640_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000001329 249.0
PYH1_k127_2754741_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 303.0
PYH1_k127_2754741_1 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000000000009711 172.0
PYH1_k127_2754741_2 - - - - 0.00000000000005675 74.0
PYH1_k127_2754807_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 300.0
PYH1_k127_2754807_1 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000002707 169.0
PYH1_k127_2754807_2 translation initiation factor activity K03699 - - 0.00001448 49.0
PYH1_k127_2761675_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 454.0
PYH1_k127_2761675_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000002948 131.0
PYH1_k127_2775889_0 GAF domain - - - 1.158e-199 642.0
PYH1_k127_2775889_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 422.0
PYH1_k127_2775889_2 phosphorelay signal transduction system - - - 0.00000000000000000000000004776 109.0
PYH1_k127_27827_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 544.0
PYH1_k127_27827_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 535.0
PYH1_k127_27827_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 471.0
PYH1_k127_27827_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 281.0
PYH1_k127_27827_4 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000825 272.0
PYH1_k127_27827_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004055 265.0
PYH1_k127_27827_6 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000653 167.0
PYH1_k127_27827_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000007519 144.0
PYH1_k127_2789650_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.881e-205 646.0
PYH1_k127_2789650_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000534 241.0
PYH1_k127_2789650_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000002198 228.0
PYH1_k127_2789650_3 MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000001396 209.0
PYH1_k127_2789650_4 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001066 207.0
PYH1_k127_2811367_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 539.0
PYH1_k127_2811367_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 321.0
PYH1_k127_2811367_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000001082 256.0
PYH1_k127_2811367_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000005545 250.0
PYH1_k127_2811367_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000008844 204.0
PYH1_k127_2811367_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000219 175.0
PYH1_k127_2811367_6 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000000008279 122.0
PYH1_k127_2811367_7 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000001899 108.0
PYH1_k127_2871856_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 419.0
PYH1_k127_2871856_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000008031 267.0
PYH1_k127_2871856_2 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000002494 175.0
PYH1_k127_2871856_3 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000001186 182.0
PYH1_k127_2871856_4 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000001056 109.0
PYH1_k127_2873487_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 383.0
PYH1_k127_2873487_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 364.0
PYH1_k127_2873487_2 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000000005205 153.0
PYH1_k127_2873487_3 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000003081 114.0
PYH1_k127_2944569_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 572.0
PYH1_k127_2944569_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000001057 79.0
PYH1_k127_2944569_2 Mut7-C RNAse domain K09122 - - 0.000000007852 57.0
PYH1_k127_299816_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 312.0
PYH1_k127_299816_1 - - - - 0.0000000000000000427 85.0
PYH1_k127_299816_2 nucleotidyltransferase activity K07075 - - 0.000000000000005082 76.0
PYH1_k127_299816_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000001516 67.0
PYH1_k127_299816_4 - - - - 0.000000002175 61.0
PYH1_k127_3010520_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.093e-318 981.0
PYH1_k127_3010520_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 564.0
PYH1_k127_3010520_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000006801 224.0
PYH1_k127_3010520_3 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000001791 90.0
PYH1_k127_3010520_5 - - - - 0.0000272 47.0
PYH1_k127_3020933_0 metal ion transport K14445 - - 1.388e-258 803.0
PYH1_k127_3020933_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000003296 73.0
PYH1_k127_3020933_2 IMP dehydrogenase activity - - - 0.0000000003413 61.0
PYH1_k127_3034418_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
PYH1_k127_3034418_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000005116 228.0
PYH1_k127_3034418_2 enoyl-[acyl-carrier-protein] reductase (NADH) activity - - - 0.000000000000000000009633 98.0
PYH1_k127_3034418_3 PFAM Nucleotidyltransferase domain - - - 0.000000009802 61.0
PYH1_k127_3091754_0 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 417.0
PYH1_k127_3091754_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000006598 129.0
PYH1_k127_3091754_2 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000441 78.0
PYH1_k127_3091754_3 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.0000000000002978 80.0
PYH1_k127_3093394_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.046e-196 618.0
PYH1_k127_3093394_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000883 85.0
PYH1_k127_31175_0 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000001626 255.0
PYH1_k127_31175_1 Zincin-like metallopeptidase - - - 0.0000000000000000000004403 100.0
PYH1_k127_31175_2 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.000000000002353 81.0
PYH1_k127_3162730_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.081e-238 757.0
PYH1_k127_3162730_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 374.0
PYH1_k127_3162730_2 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001455 268.0
PYH1_k127_3162730_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000006689 159.0
PYH1_k127_3162730_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000003241 122.0
PYH1_k127_3162730_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000001389 104.0
PYH1_k127_3162730_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000006117 58.0
PYH1_k127_3178663_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 395.0
PYH1_k127_3178663_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007191 248.0
PYH1_k127_3178663_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000004299 214.0
PYH1_k127_3178663_3 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000000000001307 192.0
PYH1_k127_322636_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.846e-202 639.0
PYH1_k127_322636_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 520.0
PYH1_k127_3244615_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 323.0
PYH1_k127_3244615_1 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000004325 115.0
PYH1_k127_3244615_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000007069 66.0
PYH1_k127_3277394_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 369.0
PYH1_k127_3277394_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003786 263.0
PYH1_k127_3277394_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000009281 204.0
PYH1_k127_3277394_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000121 171.0
PYH1_k127_3277394_4 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000006301 163.0
PYH1_k127_3277394_5 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000114 142.0
PYH1_k127_3277394_6 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000004698 68.0
PYH1_k127_3277394_8 TonB C terminal K03646 - - 0.0001945 52.0
PYH1_k127_3283651_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 334.0
PYH1_k127_3283651_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000002035 185.0
PYH1_k127_3283651_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000304 61.0
PYH1_k127_3346284_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000002293 213.0
PYH1_k127_3413904_0 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 289.0
PYH1_k127_3413904_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001809 237.0
PYH1_k127_3413904_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000004539 237.0
PYH1_k127_3413904_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000006561 126.0
PYH1_k127_3413904_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.00000000006121 68.0
PYH1_k127_3496049_0 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000000000000000000000000000000000000000000003409 213.0
PYH1_k127_3496049_1 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.00000000001348 75.0
PYH1_k127_3518487_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 442.0
PYH1_k127_3518487_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001971 275.0
PYH1_k127_3518487_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002557 248.0
PYH1_k127_3518487_3 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000007297 130.0
PYH1_k127_3536584_0 arsenite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 458.0
PYH1_k127_3536584_1 Potassium uptake system protein K03499 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000007975 220.0
PYH1_k127_3536584_2 Cation transport protein K03498 - - 0.000000000000000000000000009053 113.0
PYH1_k127_3559581_0 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000009038 207.0
PYH1_k127_3559581_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000006151 196.0
PYH1_k127_3559581_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000007982 133.0
PYH1_k127_3607020_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 590.0
PYH1_k127_3607020_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 394.0
PYH1_k127_3607020_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 372.0
PYH1_k127_3607020_3 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000006515 175.0
PYH1_k127_3607020_4 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000005714 120.0
PYH1_k127_3667178_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000003598 220.0
PYH1_k127_3667178_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001134 210.0
PYH1_k127_3667178_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002607 178.0
PYH1_k127_3667178_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000008003 142.0
PYH1_k127_3667178_4 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000001086 70.0
PYH1_k127_3667178_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000827 66.0
PYH1_k127_368269_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 580.0
PYH1_k127_368269_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 483.0
PYH1_k127_368269_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 341.0
PYH1_k127_368269_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 319.0
PYH1_k127_368269_4 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000001703 247.0
PYH1_k127_368269_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000004677 180.0
PYH1_k127_368269_6 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000005765 124.0
PYH1_k127_368269_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000005811 90.0
PYH1_k127_368269_8 Glutaredoxin K03676 - - 0.00000000000000003348 81.0
PYH1_k127_368269_9 transporter K07238 - - 0.000000000009959 67.0
PYH1_k127_3691072_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 578.0
PYH1_k127_3691072_1 LysM domain K08307,K12204,K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 338.0
PYH1_k127_3703207_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 310.0
PYH1_k127_3703207_1 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000002896 158.0
PYH1_k127_3705678_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 353.0
PYH1_k127_3705678_1 proton-transporting ATP synthase activity, rotational mechanism K02115 - - 0.000000000000000000000000000000398 133.0
PYH1_k127_3708234_0 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000001523 234.0
PYH1_k127_3708234_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000003755 228.0
PYH1_k127_3708234_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000467 164.0
PYH1_k127_3708234_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000000000000000000000001457 135.0
PYH1_k127_3709296_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.193e-236 743.0
PYH1_k127_3709296_1 Phosphoglycerate kinase K00927 - 2.7.2.3 6.193e-198 624.0
PYH1_k127_3709296_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000004776 243.0
PYH1_k127_3709296_3 - - - - 0.0000000000000000000000000000000000000000000000000000000005771 211.0
PYH1_k127_3709296_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000004945 180.0
PYH1_k127_3709296_5 Belongs to the UPF0434 family K09791 - - 0.0000000000000002073 80.0
PYH1_k127_3737887_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000007078 217.0
PYH1_k127_3737887_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000005429 121.0
PYH1_k127_3802833_0 4Fe-4S binding domain - - - 3.868e-220 693.0
PYH1_k127_3802833_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 387.0
PYH1_k127_3802833_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
PYH1_k127_3802833_3 - - - - 0.000000000000000000000000000000000000007446 151.0
PYH1_k127_3802833_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000001881 138.0
PYH1_k127_3802833_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000001747 85.0
PYH1_k127_3843784_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000005936 205.0
PYH1_k127_3850922_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 595.0
PYH1_k127_3850922_1 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 427.0
PYH1_k127_3850922_2 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000003008 257.0
PYH1_k127_3850922_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000003498 198.0
PYH1_k127_3850922_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000002544 182.0
PYH1_k127_3850922_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000006324 123.0
PYH1_k127_3863418_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 293.0
PYH1_k127_3863418_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000003573 211.0
PYH1_k127_3863418_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000007457 211.0
PYH1_k127_3863418_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000006166 163.0
PYH1_k127_3863418_4 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000000001909 130.0
PYH1_k127_3863418_5 Ribosomal protein S16 K02959 - - 0.0000000000000000000000000008381 113.0
PYH1_k127_3896717_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 522.0
PYH1_k127_3896717_1 TIGRFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
PYH1_k127_3900733_0 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 417.0
PYH1_k127_3900733_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000003936 235.0
PYH1_k127_3900733_2 - - - - 0.00000000000000000000000000000000000000000000000000000000006532 210.0
PYH1_k127_3900733_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000002406 174.0
PYH1_k127_3900733_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000003612 170.0
PYH1_k127_3900733_5 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000009009 170.0
PYH1_k127_3913668_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 452.0
PYH1_k127_3913668_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 442.0
PYH1_k127_3913668_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000212 231.0
PYH1_k127_3913668_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008566 221.0
PYH1_k127_3913668_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000004849 226.0
PYH1_k127_3913668_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000001983 156.0
PYH1_k127_3955488_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 3.035e-246 777.0
PYH1_k127_3956026_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000004132 237.0
PYH1_k127_3956026_1 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000009586 145.0
PYH1_k127_3956026_2 oligosaccharyl transferase activity - - - 0.0000000000001139 76.0
PYH1_k127_3965063_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 501.0
PYH1_k127_3965063_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000105 154.0
PYH1_k127_3965063_2 phosphoribosylformylglycinamidine synthase, chloroplastic K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0007275,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0030554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048229,GO:0048856,GO:0055046,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.3.5.3 0.0000000000000000000000000007237 116.0
PYH1_k127_3995423_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.057e-214 671.0
PYH1_k127_3995423_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000001555 194.0
PYH1_k127_3995423_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000001285 173.0
PYH1_k127_3995423_3 thiolester hydrolase activity K03186 - 2.5.1.129 0.0000000000000000000000000002395 118.0
PYH1_k127_3995423_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000001034 114.0
PYH1_k127_3995423_5 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.0000000000005034 71.0
PYH1_k127_4019240_0 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 312.0
PYH1_k127_4019240_1 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000001161 133.0
PYH1_k127_4019240_2 Transposase IS200 like - - - 0.00000000000000000000000003161 109.0
PYH1_k127_4028057_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 413.0
PYH1_k127_4028057_1 AMP binding - - - 0.0000000000000000000000000000000000007427 146.0
PYH1_k127_404782_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 528.0
PYH1_k127_404782_1 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 289.0
PYH1_k127_4065202_0 - - - - 0.000000618 51.0
PYH1_k127_4065202_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000498 59.0
PYH1_k127_409665_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 459.0
PYH1_k127_409665_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000004351 265.0
PYH1_k127_409665_2 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000001382 204.0
PYH1_k127_4154330_0 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000001072 250.0
PYH1_k127_4154330_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000607 207.0
PYH1_k127_4183792_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 5.377e-196 616.0
PYH1_k127_4183792_1 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 419.0
PYH1_k127_4183792_2 - - - - 0.0000000000000000000000000000000000004415 151.0
PYH1_k127_4188280_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.509e-281 876.0
PYH1_k127_4188280_1 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 370.0
PYH1_k127_4188280_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000001675 94.0
PYH1_k127_4259307_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 484.0
PYH1_k127_4259307_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 364.0
PYH1_k127_4259307_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000002047 229.0
PYH1_k127_4259307_3 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000006993 138.0
PYH1_k127_4259307_4 - - - - 0.00000000000000000000000007287 115.0
PYH1_k127_4267873_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 606.0
PYH1_k127_4267873_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 507.0
PYH1_k127_4267873_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000001256 195.0
PYH1_k127_4267873_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000001077 133.0
PYH1_k127_4267873_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000419 49.0
PYH1_k127_4282230_0 FeoA K04759 - - 3.574e-275 860.0
PYH1_k127_4282230_1 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000008753 126.0
PYH1_k127_4282230_2 self proteolysis - - - 0.00000000000000000000007208 107.0
PYH1_k127_4282230_3 FeoA K04759 - - 0.00000000000004481 75.0
PYH1_k127_4313816_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.498e-209 662.0
PYH1_k127_4313816_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 493.0
PYH1_k127_4313816_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
PYH1_k127_4313816_3 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 297.0
PYH1_k127_4313816_4 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
PYH1_k127_4313816_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000005162 224.0
PYH1_k127_4313816_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000006404 209.0
PYH1_k127_4313816_7 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000004929 199.0
PYH1_k127_4313816_8 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000006628 90.0
PYH1_k127_4327697_0 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 603.0
PYH1_k127_4327697_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000001347 213.0
PYH1_k127_4327697_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000001251 132.0
PYH1_k127_4327697_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000001132 90.0
PYH1_k127_4340845_0 carboxylic ester hydrolase activity K00433 - 1.11.1.10 0.00000000000000000000001689 110.0
PYH1_k127_4340845_1 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000004741 98.0
PYH1_k127_4340845_2 YsiA-like protein, C-terminal region K13770 - - 0.0000000002273 69.0
PYH1_k127_4384095_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.341e-197 621.0
PYH1_k127_4384095_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000341 240.0
PYH1_k127_4384095_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
PYH1_k127_4384095_3 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000008249 104.0
PYH1_k127_4384095_4 Sporulation and spore germination - - - 0.0000000001024 70.0
PYH1_k127_4396126_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.561e-209 664.0
PYH1_k127_4396126_1 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 346.0
PYH1_k127_4396126_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 304.0
PYH1_k127_4396126_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000001298 224.0
PYH1_k127_4396126_4 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000007311 196.0
PYH1_k127_4396126_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000007051 158.0
PYH1_k127_4396126_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000001542 139.0
PYH1_k127_4396126_7 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000000006222 121.0
PYH1_k127_4396126_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000002062 89.0
PYH1_k127_4402138_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 399.0
PYH1_k127_4402138_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000005194 210.0
PYH1_k127_4406721_0 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 514.0
PYH1_k127_4406721_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 513.0
PYH1_k127_4406721_10 Nitroreductase family - - - 0.0004185 44.0
PYH1_k127_4406721_2 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 318.0
PYH1_k127_4406721_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 284.0
PYH1_k127_4406721_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000004667 199.0
PYH1_k127_4406721_5 Large extracellular alpha-helical protein - - - 0.00000000000000000182 97.0
PYH1_k127_4406721_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001906 80.0
PYH1_k127_4406721_7 cellulase activity - - - 0.000000003277 68.0
PYH1_k127_4406721_8 Protein of unknown function (DUF2934) - - - 0.00000008406 56.0
PYH1_k127_4406721_9 PFAM ATP-binding region ATPase domain protein - - - 0.000001052 51.0
PYH1_k127_4410995_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 520.0
PYH1_k127_4410995_1 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
PYH1_k127_4410995_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000001563 222.0
PYH1_k127_4410995_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000003879 137.0
PYH1_k127_4410995_4 Histidine Phosphotransfer domain K02487,K06596 - - 0.0001648 50.0
PYH1_k127_447048_0 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001547 270.0
PYH1_k127_447048_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000004061 229.0
PYH1_k127_447048_2 glycosyl transferase, family 39 - - - 0.000002552 60.0
PYH1_k127_4479398_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 487.0
PYH1_k127_4564832_0 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 435.0
PYH1_k127_4564832_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
PYH1_k127_4564832_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000001952 139.0
PYH1_k127_4564832_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000001822 119.0
PYH1_k127_4579415_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 512.0
PYH1_k127_4579415_1 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000001374 195.0
PYH1_k127_4579415_2 PFAM NifU-like domain - - - 0.000000000000000000000001768 104.0
PYH1_k127_4610077_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 297.0
PYH1_k127_4610077_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000008243 206.0
PYH1_k127_4610077_2 SRPBCC domain-containing protein - - - 0.000000000000000000000000000001554 128.0
PYH1_k127_4610077_4 PFAM Methyltransferase - - - 0.00000002491 55.0
PYH1_k127_4620317_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1054.0
PYH1_k127_4620317_1 PFAM transposase, IS4 family protein - - - 0.0000000000001725 72.0
PYH1_k127_4620317_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity - - - 0.000000002994 59.0
PYH1_k127_4621785_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000007661 151.0
PYH1_k127_4621785_2 Leucine rich repeat variant - - - 0.00000002622 60.0
PYH1_k127_4663503_0 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000002889 176.0
PYH1_k127_4663503_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000003258 167.0
PYH1_k127_4663503_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000008947 140.0
PYH1_k127_4669169_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000136 232.0
PYH1_k127_4669169_1 Tetratricopeptide repeat - - - 0.0000000000002116 79.0
PYH1_k127_4669169_2 Sporulation related domain - - - 0.0000535 54.0
PYH1_k127_4693321_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 6.938e-206 648.0
PYH1_k127_4693321_1 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000002307 184.0
PYH1_k127_4693321_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000003666 143.0
PYH1_k127_4697218_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 539.0
PYH1_k127_4697218_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 443.0
PYH1_k127_4697218_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 399.0
PYH1_k127_4697218_3 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 389.0
PYH1_k127_4697218_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 387.0
PYH1_k127_4697218_5 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 360.0
PYH1_k127_4697218_6 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000002597 240.0
PYH1_k127_4697218_7 Sulfurtransferase TusA - - - 0.00000000000000000000000659 102.0
PYH1_k127_4697218_8 Essential cell division protein K03589 - - 0.0000000000000003051 88.0
PYH1_k127_4697218_9 PFAM HD domain - - - 0.0000879 45.0
PYH1_k127_4707555_0 Glycosyl hydrolases family 15 - - - 5.766e-200 636.0
PYH1_k127_4707555_1 Rubrerythrin - - - 0.00000000000000000000000000001197 120.0
PYH1_k127_4707555_2 Protein of unknown function (DUF2769) - - - 0.0000000000000007312 79.0
PYH1_k127_4781159_0 sulfuric ester hydrolase activity K07014 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000001198 227.0
PYH1_k127_4781159_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
PYH1_k127_4781159_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000005351 175.0
PYH1_k127_4781159_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000002291 139.0
PYH1_k127_4819556_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000004218 133.0
PYH1_k127_4819556_1 Large extracellular alpha-helical protein - - - 0.00000000000000000002989 102.0
PYH1_k127_4819556_2 Bacterial PH domain - - - 0.000001509 54.0
PYH1_k127_4830067_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 303.0
PYH1_k127_4830067_1 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000005554 225.0
PYH1_k127_4830067_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000007492 216.0
PYH1_k127_4830067_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000001664 174.0
PYH1_k127_4830355_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 338.0
PYH1_k127_4855673_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001165 281.0
PYH1_k127_4855673_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000001341 112.0
PYH1_k127_4855673_2 Tetratricopeptide repeat - - - 0.0000000000000000000000005833 113.0
PYH1_k127_4855673_3 fibronectin type III domain protein - - - 0.0000000000000001907 87.0
PYH1_k127_4911149_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000001193 203.0
PYH1_k127_4911149_1 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000001113 168.0
PYH1_k127_4911149_2 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000004402 171.0
PYH1_k127_4960933_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
PYH1_k127_4960933_1 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.00000000000000000000000000000000000000000000000000000000000000000216 229.0
PYH1_k127_4960933_2 NTPase - - - 0.000000000000000000000000000000000000000000000000000004546 195.0
PYH1_k127_4960933_3 - - - - 0.0000000000000000000000000000000000000000000000000006659 190.0
PYH1_k127_4960933_4 Protein of unknown function (DUF1318) - - - 0.0000000000001388 71.0
PYH1_k127_4962267_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 608.0
PYH1_k127_4962267_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 468.0
PYH1_k127_4962267_2 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000001258 238.0
PYH1_k127_4962267_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000003597 228.0
PYH1_k127_4962267_4 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000004946 73.0
PYH1_k127_4992234_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 5.855e-197 621.0
PYH1_k127_4992234_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 548.0
PYH1_k127_504658_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 449.0
PYH1_k127_504658_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000001594 220.0
PYH1_k127_504658_3 DUF218 domain - - - 0.000001025 55.0
PYH1_k127_506613_0 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 527.0
PYH1_k127_506613_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 470.0
PYH1_k127_506613_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 427.0
PYH1_k127_506613_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 388.0
PYH1_k127_506613_5 SMART Tetratricopeptide repeat - - - 0.0002778 52.0
PYH1_k127_5120120_0 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 3.952e-237 749.0
PYH1_k127_5120120_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 432.0
PYH1_k127_5120120_2 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 345.0
PYH1_k127_5120120_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000002449 176.0
PYH1_k127_5120120_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000002838 146.0
PYH1_k127_5120120_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000008703 117.0
PYH1_k127_516336_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 438.0
PYH1_k127_516336_1 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 374.0
PYH1_k127_516336_2 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000005658 240.0
PYH1_k127_516336_3 Radical SAM K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000004205 233.0
PYH1_k127_516336_4 Radical SAM superfamily - - - 0.00000000000000001253 93.0
PYH1_k127_5192142_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 588.0
PYH1_k127_5192142_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007081 258.0
PYH1_k127_5192142_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000003434 183.0
PYH1_k127_5192142_3 GYD domain - - - 0.00000000000000000000000000000004894 130.0
PYH1_k127_5192142_4 PFAM nitrogen-fixing NifU domain protein - - - 0.000000004553 60.0
PYH1_k127_5197670_0 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 358.0
PYH1_k127_5197670_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007554 250.0
PYH1_k127_5197670_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
PYH1_k127_5215974_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 565.0
PYH1_k127_5215974_1 Domain of unknown function (DUF4912) K09942 - - 0.00000000000009376 81.0
PYH1_k127_5215974_2 Type II secretion system protein B K02451 - - 0.000000000005078 74.0
PYH1_k127_5241602_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 308.0
PYH1_k127_5241602_1 - - - - 0.000000000000000000000000000000000000000000000000000003864 197.0
PYH1_k127_5241602_2 SMART Cold shock protein K03704 - - 0.0000000000000000000000003743 107.0
PYH1_k127_525951_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 328.0
PYH1_k127_525951_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005009 279.0
PYH1_k127_525951_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001606 282.0
PYH1_k127_5285881_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 356.0
PYH1_k127_5285881_1 Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000007255 265.0
PYH1_k127_5285881_2 manually curated - - - 0.000000000000000000000000963 106.0
PYH1_k127_5285881_3 PFAM S23 ribosomal protein - - - 0.0000000000000585 72.0
PYH1_k127_5285881_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000008758 48.0
PYH1_k127_5293018_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 379.0
PYH1_k127_5293018_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000005433 117.0
PYH1_k127_5293018_2 Tetratricopeptide repeat - - - 0.0000000000000000000001621 104.0
PYH1_k127_5293018_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000006157 55.0
PYH1_k127_5296005_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 541.0
PYH1_k127_5296005_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 392.0
PYH1_k127_5306331_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000593 239.0
PYH1_k127_5306331_1 Potassium uptake protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
PYH1_k127_5306331_2 - - - - 0.000000001481 60.0
PYH1_k127_5320338_0 heat shock protein binding - - - 0.0000002185 64.0
PYH1_k127_5320338_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000369 46.0
PYH1_k127_536114_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 4.335e-277 866.0
PYH1_k127_536114_1 Carbon starvation protein K06200 - - 1.157e-259 815.0
PYH1_k127_536114_10 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000003533 183.0
PYH1_k127_536114_11 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000007319 153.0
PYH1_k127_536114_2 Protein conserved in bacteria - - - 7.592e-241 771.0
PYH1_k127_536114_3 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 602.0
PYH1_k127_536114_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 366.0
PYH1_k127_536114_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 335.0
PYH1_k127_536114_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008669 280.0
PYH1_k127_536114_7 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 263.0
PYH1_k127_536114_8 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001665 260.0
PYH1_k127_536114_9 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000002179 216.0
PYH1_k127_5388529_0 CHASE2 K01768 - 4.6.1.1 4.665e-245 777.0
PYH1_k127_5392541_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005987 275.0
PYH1_k127_5392541_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004803 273.0
PYH1_k127_5392541_2 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000001773 73.0
PYH1_k127_539264_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
PYH1_k127_539264_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005795 285.0
PYH1_k127_5392914_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 585.0
PYH1_k127_5392914_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000008365 139.0
PYH1_k127_5447305_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 460.0
PYH1_k127_5447305_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 381.0
PYH1_k127_5447305_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 379.0
PYH1_k127_5447305_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 314.0
PYH1_k127_5447305_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000452 285.0
PYH1_k127_5447305_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000001618 194.0
PYH1_k127_5447305_6 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000006107 113.0
PYH1_k127_547608_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.508e-200 629.0
PYH1_k127_547608_1 Beta-Casp domain K07576 - - 0.0000000000000000000003616 97.0
PYH1_k127_548743_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 604.0
PYH1_k127_548743_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 434.0
PYH1_k127_548743_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000003482 146.0
PYH1_k127_548743_3 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000003636 122.0
PYH1_k127_548743_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000004411 89.0
PYH1_k127_5512559_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 605.0
PYH1_k127_5512559_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 424.0
PYH1_k127_5512559_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
PYH1_k127_5512559_3 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000008726 204.0
PYH1_k127_5537065_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.847e-262 814.0
PYH1_k127_5537065_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000001013 155.0
PYH1_k127_5569076_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 370.0
PYH1_k127_5569076_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000006456 225.0
PYH1_k127_5569076_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000001857 158.0
PYH1_k127_5614074_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 511.0
PYH1_k127_5614074_1 lyase activity - - - 0.0000000000000000000000000000002798 128.0
PYH1_k127_5614074_2 Putative regulatory protein - - - 0.0000000000000184 76.0
PYH1_k127_5651858_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 397.0
PYH1_k127_5661183_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 549.0
PYH1_k127_5661183_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 443.0
PYH1_k127_5661183_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 323.0
PYH1_k127_5661183_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000002207 145.0
PYH1_k127_5661183_4 NIL - - - 0.00000000000000000000000000000103 122.0
PYH1_k127_5662819_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 458.0
PYH1_k127_5662819_1 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000005779 171.0
PYH1_k127_5662819_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000002441 58.0
PYH1_k127_5667469_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.798e-249 778.0
PYH1_k127_5667469_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 611.0
PYH1_k127_5667469_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 396.0
PYH1_k127_5667469_3 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 289.0
PYH1_k127_5667469_4 Elongation factor G, domain IV K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 286.0
PYH1_k127_5672545_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004384 291.0
PYH1_k127_5672545_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000006679 141.0
PYH1_k127_5703327_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 529.0
PYH1_k127_5703327_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 356.0
PYH1_k127_572063_0 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 3.514e-224 709.0
PYH1_k127_572063_1 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000004609 151.0
PYH1_k127_572063_2 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000000000115 115.0
PYH1_k127_5776474_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 421.0
PYH1_k127_5776474_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 414.0
PYH1_k127_5776474_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 339.0
PYH1_k127_5776474_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 334.0
PYH1_k127_5776474_4 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
PYH1_k127_5776474_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000002909 198.0
PYH1_k127_5776474_6 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000002035 164.0
PYH1_k127_5779676_0 NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 380.0
PYH1_k127_5779676_1 - - - - 0.0000000000000000000000007482 111.0
PYH1_k127_5779903_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 318.0
PYH1_k127_5779903_1 Cobalt transport protein K02008 - - 0.000000000000000000000000000000132 128.0
PYH1_k127_5899599_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.328e-254 798.0
PYH1_k127_5899599_1 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 449.0
PYH1_k127_5909518_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.995e-197 623.0
PYH1_k127_5909518_1 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 314.0
PYH1_k127_5909518_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000362 135.0
PYH1_k127_5909518_3 Putative zinc- or iron-chelating domain - - - 0.00000000000000237 78.0
PYH1_k127_5912662_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 351.0
PYH1_k127_5912662_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 326.0
PYH1_k127_5912662_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000008439 173.0
PYH1_k127_5912662_3 - - - - 0.0000000000000000000000000000722 117.0
PYH1_k127_592658_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 327.0
PYH1_k127_5935157_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 614.0
PYH1_k127_5935157_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 545.0
PYH1_k127_5935157_2 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001196 262.0
PYH1_k127_5935157_3 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000002991 205.0
PYH1_k127_5935157_4 competence protein - - - 0.000000000000000000000000000000000000000001365 165.0
PYH1_k127_5935157_5 - - - - 0.000000007052 63.0
PYH1_k127_5935157_6 Tetratricopeptide repeat - - - 0.000005196 57.0
PYH1_k127_5949578_0 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 513.0
PYH1_k127_5949578_1 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 436.0
PYH1_k127_5949578_2 PFAM diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000001444 184.0
PYH1_k127_5949578_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000002556 126.0
PYH1_k127_5949578_4 Zinc-uptake complex component A periplasmic K09815 - - 0.0001125 48.0
PYH1_k127_5981359_0 family UPF0324 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 291.0
PYH1_k127_5981359_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000633 121.0
PYH1_k127_5981359_2 Universal stress protein family - - - 0.000000000000000001659 92.0
PYH1_k127_5981359_3 PFAM Methylamine - - - 0.00000000000000004834 87.0
PYH1_k127_5981359_4 - - - - 0.0003498 50.0
PYH1_k127_5982833_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 323.0
PYH1_k127_5982833_1 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000008958 266.0
PYH1_k127_5982833_2 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000008223 244.0
PYH1_k127_5982833_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000006302 121.0
PYH1_k127_5993945_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
PYH1_k127_5993945_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000002563 169.0
PYH1_k127_5993945_2 enoyl-[acyl-carrier-protein] reductase (NADH) activity - - - 0.000000000000000000000000000000137 127.0
PYH1_k127_6000114_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009859 248.0
PYH1_k127_6000114_1 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000007938 227.0
PYH1_k127_6009657_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000009724 239.0
PYH1_k127_6009657_1 Sec61beta family - - - 0.000000003511 60.0
PYH1_k127_6009657_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00001734 49.0
PYH1_k127_6009807_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 354.0
PYH1_k127_6009807_1 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 312.0
PYH1_k127_6009807_2 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001273 282.0
PYH1_k127_6009807_3 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008992 286.0
PYH1_k127_6009807_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005329 249.0
PYH1_k127_6009807_5 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000004642 220.0
PYH1_k127_6009807_6 Protein conserved in bacteria K07011 - - 0.00000000000000000000000000000000000000000000000001084 188.0
PYH1_k127_6009807_7 Protein of unknown function (DUF2905) - - - 0.00000000000000000000004123 100.0
PYH1_k127_6009807_8 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000002056 57.0
PYH1_k127_6011819_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 525.0
PYH1_k127_6011819_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000007424 100.0
PYH1_k127_6016337_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 8.62e-307 947.0
PYH1_k127_6016337_1 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001272 262.0
PYH1_k127_6016337_2 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000008184 245.0
PYH1_k127_6016337_3 Chromate K07240 - - 0.00000000000000000000000000000003473 132.0
PYH1_k127_6016337_4 Chromate transporter K07240 - - 0.00000000000000000000000000000003473 132.0
PYH1_k127_6027464_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000001106 215.0
PYH1_k127_6031958_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 571.0
PYH1_k127_6031958_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 574.0
PYH1_k127_6031958_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 295.0
PYH1_k127_6031958_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000001163 77.0
PYH1_k127_6080546_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 2.278e-249 775.0
PYH1_k127_6080546_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 366.0
PYH1_k127_6087714_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 473.0
PYH1_k127_6087714_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000008519 126.0
PYH1_k127_6091816_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 524.0
PYH1_k127_6091816_1 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000006191 229.0
PYH1_k127_6091816_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000008117 185.0
PYH1_k127_6091816_3 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000001072 161.0
PYH1_k127_6108112_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 5.96e-262 830.0
PYH1_k127_6108112_1 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 329.0
PYH1_k127_6108112_2 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000163 261.0
PYH1_k127_6108112_3 Alginate export - - - 0.000000000000000000000000000000000000000000000000033 190.0
PYH1_k127_6108112_4 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.00000000000000001957 84.0
PYH1_k127_6113623_0 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 465.0
PYH1_k127_6113623_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 301.0
PYH1_k127_6113623_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 298.0
PYH1_k127_6113623_3 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000001683 229.0
PYH1_k127_6113623_4 Hydrogenase maturation protease K03605 - - 0.000000000000000005932 89.0
PYH1_k127_6113623_5 Polymer-forming cytoskeletal - - - 0.000000000000000008646 87.0
PYH1_k127_6113623_6 Belongs to the 'phage' integrase family - - - 0.0000000000007826 70.0
PYH1_k127_6113623_7 - - - - 0.000001979 49.0
PYH1_k127_6154816_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.021e-253 803.0
PYH1_k127_6154816_1 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 309.0
PYH1_k127_6154816_2 PINc domain ribonuclease K09006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
PYH1_k127_6154816_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000003043 237.0
PYH1_k127_6154816_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000007259 226.0
PYH1_k127_6154816_5 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000167 176.0
PYH1_k127_6154816_6 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000001533 86.0
PYH1_k127_6157861_0 PFAM Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 471.0
PYH1_k127_6157861_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000006383 113.0
PYH1_k127_6157861_2 heat shock protein binding - - - 0.00000000000000000000009247 109.0
PYH1_k127_6184607_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 3.66e-248 806.0
PYH1_k127_6184607_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 352.0
PYH1_k127_6184607_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000008634 68.0
PYH1_k127_6184607_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001148 284.0
PYH1_k127_6184607_3 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000009409 241.0
PYH1_k127_6184607_4 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000006157 213.0
PYH1_k127_6184607_6 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000006955 119.0
PYH1_k127_6184607_7 SMART Cold shock protein K03704 - - 0.0000000000000000000000006362 105.0
PYH1_k127_6184607_8 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000006995 107.0
PYH1_k127_6230814_0 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000002759 209.0
PYH1_k127_6230814_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000009715 208.0
PYH1_k127_6230814_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000002482 193.0
PYH1_k127_6230814_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000003044 169.0
PYH1_k127_6230814_4 DnaJ molecular chaperone homology domain - - - 0.0000001165 64.0
PYH1_k127_623284_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.437e-282 876.0
PYH1_k127_623284_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000002014 77.0
PYH1_k127_6249234_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001916 265.0
PYH1_k127_6249234_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000005778 50.0
PYH1_k127_6259526_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 600.0
PYH1_k127_6259526_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000173 199.0
PYH1_k127_6265024_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 373.0
PYH1_k127_6265024_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000671 239.0
PYH1_k127_626604_0 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000001558 166.0
PYH1_k127_626604_1 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000002122 116.0
PYH1_k127_626604_2 Protein of unknown function (DUF507) - - - 0.000000000000000000000000002701 114.0
PYH1_k127_626604_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000002043 109.0
PYH1_k127_626604_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000003634 97.0
PYH1_k127_6271445_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 606.0
PYH1_k127_6280964_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 307.0
PYH1_k127_6280964_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 298.0
PYH1_k127_6301823_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
PYH1_k127_6301823_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000006801 160.0
PYH1_k127_6301823_2 CHASE3 domain - - - 0.00000002041 57.0
PYH1_k127_6340021_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 307.0
PYH1_k127_6340021_1 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000052 286.0
PYH1_k127_6340021_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000227 211.0
PYH1_k127_6340021_3 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000003385 162.0
PYH1_k127_6340021_4 nickel-dependent hydrogenase large subunit - - - 0.00000000000000000000000000000000000000006506 158.0
PYH1_k127_6350319_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.867e-196 619.0
PYH1_k127_6350319_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 327.0
PYH1_k127_6350319_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000002963 113.0
PYH1_k127_6364303_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 512.0
PYH1_k127_6364303_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000001167 232.0
PYH1_k127_6364303_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000005365 91.0
PYH1_k127_6364303_3 Protein of unknown function (DUF721) - - - 0.00000006879 60.0
PYH1_k127_6401101_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 548.0
PYH1_k127_6411512_0 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 297.0
PYH1_k127_6411512_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000003726 109.0
PYH1_k127_6444158_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 295.0
PYH1_k127_6444158_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005445 283.0
PYH1_k127_6444158_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000004625 165.0
PYH1_k127_6444158_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000005776 167.0
PYH1_k127_6444158_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000000000001102 162.0
PYH1_k127_6444158_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000003802 138.0
PYH1_k127_6444158_6 - - - - 0.0000000000000000000000000001346 115.0
PYH1_k127_6444158_7 proteolysis K03665 - - 0.0000000000000000000000000001737 121.0
PYH1_k127_6444158_8 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000009151 99.0
PYH1_k127_6482726_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 604.0
PYH1_k127_6482726_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
PYH1_k127_6482726_2 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000009563 156.0
PYH1_k127_6482726_3 Dissimilatory sulfite reductase D (DsrD) - - - 0.0000000000000000258 84.0
PYH1_k127_6496035_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 519.0
PYH1_k127_6506877_0 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 507.0
PYH1_k127_6506877_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 486.0
PYH1_k127_6506877_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 469.0
PYH1_k127_6506877_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000003388 174.0
PYH1_k127_6506877_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000002053 152.0
PYH1_k127_6506877_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000008595 85.0
PYH1_k127_6509856_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 505.0
PYH1_k127_6509856_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000004923 203.0
PYH1_k127_6509856_2 Polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000001876 193.0
PYH1_k127_6509856_3 O-Antigen ligase K02847 - - 0.000000000000000000000000000006293 129.0
PYH1_k127_6509856_4 - - - - 0.0000000000000000000000001319 109.0
PYH1_k127_6509856_5 Spore Coat Protein U domain - - - 0.00000000006757 65.0
PYH1_k127_6509856_6 DnaJ domain protein K03686 - - 0.00002646 56.0
PYH1_k127_6509856_7 iron ion homeostasis - - - 0.00005682 53.0
PYH1_k127_6519549_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 324.0
PYH1_k127_6519549_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
PYH1_k127_6519549_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000006752 171.0
PYH1_k127_6519549_3 exonuclease activity K16899 - 3.6.4.12 0.00000000000007636 85.0
PYH1_k127_6521267_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 511.0
PYH1_k127_6521267_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 316.0
PYH1_k127_6521267_2 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001453 240.0
PYH1_k127_6521267_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000002913 61.0
PYH1_k127_6529144_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 454.0
PYH1_k127_6529144_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000005157 227.0
PYH1_k127_6529144_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000005243 221.0
PYH1_k127_6585463_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
PYH1_k127_6585463_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001359 269.0
PYH1_k127_6629506_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 451.0
PYH1_k127_6629506_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 321.0
PYH1_k127_6629963_0 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000005494 227.0
PYH1_k127_6629963_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000114 168.0
PYH1_k127_6629963_2 Tetratricopeptide repeat - - - 0.0000000000000006693 90.0
PYH1_k127_6629963_3 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0001033 54.0
PYH1_k127_6699624_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 457.0
PYH1_k127_6699624_1 Lysin motif - - - 0.0000000000000000000000008198 114.0
PYH1_k127_6702620_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 514.0
PYH1_k127_6702620_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000008444 160.0
PYH1_k127_6702620_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000005771 140.0
PYH1_k127_6702620_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000003721 53.0
PYH1_k127_6702944_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 494.0
PYH1_k127_6702944_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 462.0
PYH1_k127_6715352_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 485.0
PYH1_k127_6715352_1 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 455.0
PYH1_k127_6715352_2 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000008864 134.0
PYH1_k127_6836231_0 DNA photolyase K01669 - 4.1.99.3 3.509e-198 627.0
PYH1_k127_6836231_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 448.0
PYH1_k127_6836231_2 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000004706 145.0
PYH1_k127_6836231_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000002696 142.0
PYH1_k127_6836231_4 - - - - 0.0000000000001284 72.0
PYH1_k127_6878987_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 547.0
PYH1_k127_6878987_1 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 308.0
PYH1_k127_6903569_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 479.0
PYH1_k127_6903569_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
PYH1_k127_6903569_2 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004962 246.0
PYH1_k127_6903569_3 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000001114 181.0
PYH1_k127_6903569_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000001277 176.0
PYH1_k127_6903569_5 Prokaryotic N-terminal methylation motif K02650,K02655 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000003667 75.0
PYH1_k127_6903569_6 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000004322 59.0
PYH1_k127_6911110_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 399.0
PYH1_k127_6911110_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000003889 88.0
PYH1_k127_6911110_2 - - - - 0.00001758 52.0
PYH1_k127_6936313_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.799e-209 661.0
PYH1_k127_6936313_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 375.0
PYH1_k127_6936313_2 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.000000000000001696 78.0
PYH1_k127_6988380_0 guanyl-nucleotide exchange factor activity - - - 0.000000005688 62.0
PYH1_k127_6998793_0 Arm DNA-binding domain - - - 0.0000000001202 65.0
PYH1_k127_6998793_1 PFAM transposase IS200-family protein K07491 - - 0.0000000003967 63.0
PYH1_k127_6998793_2 - - - - 0.0000000004084 66.0
PYH1_k127_7007100_0 K06861 lipopolysaccharide export system ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 295.0
PYH1_k127_7007100_1 OstA-like protein K09774 - - 0.000000000000000000000000000000000001967 143.0
PYH1_k127_7007100_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000004177 94.0
PYH1_k127_7007100_3 AI-2E family transporter - - - 0.0000000000013 70.0
PYH1_k127_7086013_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1322.0
PYH1_k127_7086013_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
PYH1_k127_7086013_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001617 122.0
PYH1_k127_7086013_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000009691 96.0
PYH1_k127_7087958_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.113e-249 777.0
PYH1_k127_7087958_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000006226 249.0
PYH1_k127_7087958_2 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000006409 251.0
PYH1_k127_7087958_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000001884 135.0
PYH1_k127_7087958_4 Type IV pilus assembly protein PilM; K02662 - - 0.000001204 51.0
PYH1_k127_7151931_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 524.0
PYH1_k127_7151931_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 552.0
PYH1_k127_7151931_2 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 501.0
PYH1_k127_7151931_3 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 497.0
PYH1_k127_7151931_4 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 361.0
PYH1_k127_7151931_5 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 306.0
PYH1_k127_7151931_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 273.0
PYH1_k127_7151931_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000005067 216.0
PYH1_k127_7151931_8 Type II/IV secretion system protein K02454,K02652 - - 0.000000001097 59.0
PYH1_k127_7158884_0 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002464 244.0
PYH1_k127_7158884_1 methyltransferase - - - 0.00000000000000000000000000000000000003617 150.0
PYH1_k127_7158884_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.00000000000000000000000000008603 117.0
PYH1_k127_7226752_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 327.0
PYH1_k127_7226752_1 Diguanylate cyclase - - - 0.00000000000000000000000000000001685 144.0
PYH1_k127_7226752_2 Histidine kinase - - - 0.0000000000000000000000002423 122.0
PYH1_k127_7261823_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 310.0
PYH1_k127_7261823_1 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
PYH1_k127_7261823_2 SMART Rhodanese domain protein - - - 0.000000000000000000000000000000007199 129.0
PYH1_k127_7261823_3 Pyruvate phosphate dikinase - - - 0.0000001002 54.0
PYH1_k127_7309436_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 418.0
PYH1_k127_7309436_1 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001725 276.0
PYH1_k127_7309436_2 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000008648 120.0
PYH1_k127_7317667_0 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000001528 125.0
PYH1_k127_7317667_1 deoxyhypusine monooxygenase activity - - - 0.00000000000004664 79.0
PYH1_k127_7335633_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 487.0
PYH1_k127_7335633_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 473.0
PYH1_k127_7335633_2 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 404.0
PYH1_k127_7335633_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 287.0
PYH1_k127_7335633_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
PYH1_k127_7335633_5 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH1_k127_7335633_6 YGGT family K02221 - - 0.000000000000000000000000000000000142 134.0
PYH1_k127_737319_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 407.0
PYH1_k127_737319_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000007026 202.0
PYH1_k127_737319_2 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000000000007325 110.0
PYH1_k127_7390672_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 3.099e-237 747.0
PYH1_k127_7390672_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 374.0
PYH1_k127_7390672_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000009691 239.0
PYH1_k127_7390672_3 Phosphoribosyl transferase domain K07100 - - 0.000000008726 57.0
PYH1_k127_7391075_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 323.0
PYH1_k127_7391075_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005505 270.0
PYH1_k127_7391075_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000009625 64.0
PYH1_k127_7391075_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002319 239.0
PYH1_k127_7391075_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001455 201.0
PYH1_k127_7391075_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000002743 167.0
PYH1_k127_7391075_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000001247 149.0
PYH1_k127_7391075_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000009528 124.0
PYH1_k127_7391075_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001578 115.0
PYH1_k127_7391075_8 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000002122 102.0
PYH1_k127_7391075_9 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001066 76.0
PYH1_k127_7392602_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 2.139e-217 684.0
PYH1_k127_7392602_1 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 426.0
PYH1_k127_7392602_2 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000001085 170.0
PYH1_k127_7392602_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000803 168.0
PYH1_k127_7392602_4 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000002011 169.0
PYH1_k127_7471267_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.448e-202 632.0
PYH1_k127_7471267_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000009793 48.0
PYH1_k127_7471267_2 - - - - 0.0003881 44.0
PYH1_k127_7527783_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 9.429e-208 666.0
PYH1_k127_7527783_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 445.0
PYH1_k127_7527783_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 359.0
PYH1_k127_7527783_3 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 309.0
PYH1_k127_7527783_4 oxidoreductase activity K00337,K03333,K04771,K07114 - 1.1.3.6,1.6.5.3,3.4.21.107 0.000002125 55.0
PYH1_k127_7536183_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 407.0
PYH1_k127_7536183_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000706 229.0
PYH1_k127_7536183_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000001005 151.0
PYH1_k127_755296_0 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 436.0
PYH1_k127_755296_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 407.0
PYH1_k127_755296_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 390.0
PYH1_k127_755296_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000005311 193.0
PYH1_k127_755296_4 PBP superfamily domain K02040 - - 0.0000000003382 61.0
PYH1_k127_759214_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 518.0
PYH1_k127_759214_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 332.0
PYH1_k127_759214_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000004293 202.0
PYH1_k127_759214_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000002459 199.0
PYH1_k127_7618593_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 423.0
PYH1_k127_7618593_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 384.0
PYH1_k127_7618593_2 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 265.0
PYH1_k127_7618593_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000003494 182.0
PYH1_k127_7618593_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000001698 128.0
PYH1_k127_7618593_5 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000003394 111.0
PYH1_k127_7620984_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 579.0
PYH1_k127_7620984_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
PYH1_k127_7620984_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008712 238.0
PYH1_k127_7620984_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000006659 190.0
PYH1_k127_7620984_4 - - - - 0.000000000000000000000000000000000000000000001348 171.0
PYH1_k127_7620984_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000001625 144.0
PYH1_k127_7620984_6 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000005338 139.0
PYH1_k127_7620984_7 - - - - 0.000000000000000000000000000000009115 130.0
PYH1_k127_764486_0 lyase activity - - - 0.000000000000000000000000000000000000000000000000000007283 213.0
PYH1_k127_764486_1 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000007445 203.0
PYH1_k127_764486_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000007774 169.0
PYH1_k127_764486_3 Helix-turn-helix domain - - - 0.0000000000000006951 92.0
PYH1_k127_764511_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001069 201.0
PYH1_k127_764511_1 sequence-specific DNA binding K18830 - - 0.0000000000001573 74.0
PYH1_k127_764511_2 PFAM Integrase catalytic region - - - 0.000000000002147 69.0
PYH1_k127_764511_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000001222 59.0
PYH1_k127_764511_4 Transposase - - - 0.00001248 53.0
PYH1_k127_7647445_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 482.0
PYH1_k127_7647445_1 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000008764 148.0
PYH1_k127_7647445_2 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000001212 106.0
PYH1_k127_7689307_0 PFAM glycoside hydrolase, family 13 domain protein - - - 0.0000000000000006607 81.0
PYH1_k127_7689307_1 Belongs to the 'phage' integrase family K04763 - - 0.00000000006764 64.0
PYH1_k127_7689307_2 COG2202 FOG PAS PAC domain - - - 0.0000000000768 73.0
PYH1_k127_7689307_3 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0001944 45.0
PYH1_k127_7691762_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 434.0
PYH1_k127_7691762_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000004044 132.0
PYH1_k127_7691762_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000001365 122.0
PYH1_k127_7691762_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000001235 98.0
PYH1_k127_7701424_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 4.483e-196 617.0
PYH1_k127_7701424_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 441.0
PYH1_k127_7701424_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 418.0
PYH1_k127_7701424_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 294.0
PYH1_k127_7701424_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000146 181.0
PYH1_k127_7701424_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000004246 145.0
PYH1_k127_7726406_0 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 349.0
PYH1_k127_7726406_1 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 310.0
PYH1_k127_7728703_0 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
PYH1_k127_7728703_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003648 283.0
PYH1_k127_7728703_2 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000005176 123.0
PYH1_k127_7728703_3 Alternative locus ID - - - 0.0001392 50.0
PYH1_k127_7735104_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 515.0
PYH1_k127_7735104_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 366.0
PYH1_k127_7735104_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000147 254.0
PYH1_k127_7735104_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000004749 194.0
PYH1_k127_7745932_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 489.0
PYH1_k127_7745932_1 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 332.0
PYH1_k127_7745932_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000007321 145.0
PYH1_k127_7745932_3 cell cycle K05589,K12065,K13052 - - 0.000000000000001603 80.0
PYH1_k127_7745932_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0001233 46.0
PYH1_k127_7752729_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 295.0
PYH1_k127_7752729_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000001664 148.0
PYH1_k127_7752729_2 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000009464 147.0
PYH1_k127_7842553_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.045e-275 854.0
PYH1_k127_7842553_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000006869 129.0
PYH1_k127_7842553_2 SMART Elongator protein 3 MiaB NifB - - - 0.00004342 47.0
PYH1_k127_7860406_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 500.0
PYH1_k127_7860406_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 323.0
PYH1_k127_7860406_2 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000001452 194.0
PYH1_k127_7860406_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000008932 177.0
PYH1_k127_7868985_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 7.153e-212 672.0
PYH1_k127_7868985_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
PYH1_k127_7868985_2 Putative zinc-finger - - - 0.00000000000000000000000000000000000000741 157.0
PYH1_k127_7868985_3 Domain of unknown function (DUF4139) - - - 0.0000000000000003663 81.0
PYH1_k127_7873715_0 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000002128 118.0
PYH1_k127_7873715_1 ATP-dependent helicase nuclease subunit A K16898 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 0.00000000000000000001161 96.0
PYH1_k127_7912364_0 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000000000007746 192.0
PYH1_k127_7912364_1 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000897 155.0
PYH1_k127_7912364_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000001849 77.0
PYH1_k127_7964282_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000008236 205.0
PYH1_k127_7964282_1 response regulator, receiver K02485 - - 0.00000000000000000000000000000000000000000000000007187 181.0
PYH1_k127_7964282_2 PFAM response regulator receiveR - - - 0.000000000000000000000000000000000000407 145.0
PYH1_k127_7964282_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000001543 133.0
PYH1_k127_7964282_4 Diguanylate cyclase - - - 0.00000000000000000000001184 102.0
PYH1_k127_7964282_5 response regulator, receiver - - - 0.0000000000000000002424 91.0
PYH1_k127_7995833_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 345.0
PYH1_k127_7995833_1 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 339.0
PYH1_k127_7995833_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002636 273.0
PYH1_k127_7995833_3 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008424 262.0
PYH1_k127_8056010_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 408.0
PYH1_k127_8056010_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000003245 197.0
PYH1_k127_8098855_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.573e-264 823.0
PYH1_k127_8098855_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.95e-220 693.0
PYH1_k127_8098855_10 - - - - 0.000004111 50.0
PYH1_k127_8098855_2 LysM domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 344.0
PYH1_k127_8098855_3 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
PYH1_k127_8098855_4 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000001344 253.0
PYH1_k127_8098855_5 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000006134 158.0
PYH1_k127_8098855_7 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000001405 94.0
PYH1_k127_8098855_8 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000006958 70.0
PYH1_k127_8098855_9 Belongs to the HesB IscA family K15724 - - 0.000002238 51.0
PYH1_k127_8103005_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.149e-255 800.0
PYH1_k127_8103005_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 377.0
PYH1_k127_8103005_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005361 277.0
PYH1_k127_8107293_0 Peptidase family M28 - - - 9.361e-297 933.0
PYH1_k127_8107293_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 341.0
PYH1_k127_8107293_2 radical SAM domain protein K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000002457 233.0
PYH1_k127_8107553_0 DNA polymerase K02347 - - 7.505e-236 742.0
PYH1_k127_8107553_1 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 409.0
PYH1_k127_8107553_2 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 261.0
PYH1_k127_8107553_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008368 244.0
PYH1_k127_8107553_4 - - - - 0.0000000000000000000000000000000000000000000003007 169.0
PYH1_k127_8107553_5 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000004537 81.0
PYH1_k127_8129871_0 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000008095 183.0
PYH1_k127_8129871_1 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000002719 108.0
PYH1_k127_8130504_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1106.0
PYH1_k127_8130504_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 500.0
PYH1_k127_8130504_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 373.0
PYH1_k127_8130504_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000001924 204.0
PYH1_k127_8130504_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000004621 143.0
PYH1_k127_8130504_5 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000002503 98.0
PYH1_k127_8130504_7 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000007406 69.0
PYH1_k127_8133474_0 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 403.0
PYH1_k127_8133474_1 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000001814 162.0
PYH1_k127_8133474_2 - - - - 0.0000000000000000000193 96.0
PYH1_k127_8172625_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006273 289.0
PYH1_k127_8172625_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000005841 121.0
PYH1_k127_8197212_0 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 387.0
PYH1_k127_8197212_1 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001209 235.0
PYH1_k127_8197212_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001021 227.0
PYH1_k127_8246147_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 506.0
PYH1_k127_8246147_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000008329 176.0
PYH1_k127_8246147_2 phosphorelay signal transduction system K20919 - - 0.0000000000000002346 82.0
PYH1_k127_831047_0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000004068 119.0
PYH1_k127_831047_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000004097 91.0
PYH1_k127_831047_2 deoxyhypusine monooxygenase activity - - - 0.00000000000000002307 91.0
PYH1_k127_831047_3 gag-polyprotein putative aspartyl protease K06985 - - 0.0000008224 59.0
PYH1_k127_8319474_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 578.0
PYH1_k127_8319474_1 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004115 285.0
PYH1_k127_8319474_2 - - - - 0.000000000000000000000005364 104.0
PYH1_k127_8335139_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 291.0
PYH1_k127_8335139_1 PFAM Integrase catalytic - - - 0.000000000000001864 89.0
PYH1_k127_8335668_0 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000003556 183.0
PYH1_k127_8335668_1 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000008973 178.0
PYH1_k127_8335668_2 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000004064 136.0
PYH1_k127_8335668_3 Predicted RNA-binding protein - - - 0.0000000000000000000001576 98.0
PYH1_k127_8350881_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 587.0
PYH1_k127_8350881_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 295.0
PYH1_k127_8350881_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000001007 235.0
PYH1_k127_8350881_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000001082 186.0
PYH1_k127_8350881_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000006528 175.0
PYH1_k127_8350881_5 Tetratricopeptide repeat K12600 GO:0000288,GO:0000291,GO:0000785,GO:0000956,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0034655,GO:0035327,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043928,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0055087,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00008055 49.0
PYH1_k127_8360092_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 461.0
PYH1_k127_8360092_1 gas vesicle protein - - - 0.000000000000000000002336 97.0
PYH1_k127_8361781_0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000001213 208.0
PYH1_k127_8361781_1 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000001133 128.0
PYH1_k127_8361781_2 tail specific protease K03797 - 3.4.21.102 0.00000003833 54.0
PYH1_k127_878380_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 578.0
PYH1_k127_878380_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 411.0
PYH1_k127_878380_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001145 255.0
PYH1_k127_878380_3 cheY-homologous receiver domain - - - 0.0000000000007571 71.0
PYH1_k127_878851_0 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000324 278.0
PYH1_k127_878851_1 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000002442 200.0
PYH1_k127_878851_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000001896 153.0
PYH1_k127_8873_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 496.0
PYH1_k127_8873_1 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 492.0
PYH1_k127_8873_2 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 449.0
PYH1_k127_887521_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 330.0
PYH1_k127_887521_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000009821 214.0
PYH1_k127_887521_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000004308 177.0
PYH1_k127_887521_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000005929 146.0
PYH1_k127_887521_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000001074 127.0
PYH1_k127_887521_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000009111 71.0
PYH1_k127_89792_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 409.0
PYH1_k127_89792_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 402.0
PYH1_k127_901051_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 611.0
PYH1_k127_901051_1 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 431.0
PYH1_k127_901051_2 ATP-dependent peptidase activity K01338,K04076,K04770,K06915 - 3.4.21.53 0.00000000000000000000000007909 110.0
PYH1_k127_90474_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 505.0
PYH1_k127_90474_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000803 140.0
PYH1_k127_909975_0 Fructose-bisphosphate aldolase class-II - - - 6.985e-198 625.0
PYH1_k127_909975_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 522.0
PYH1_k127_909975_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 455.0
PYH1_k127_909975_3 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000009064 219.0
PYH1_k127_909975_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000008486 203.0
PYH1_k127_913667_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 576.0
PYH1_k127_913667_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 422.0
PYH1_k127_915234_0 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000004288 180.0
PYH1_k127_915234_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001517 122.0
PYH1_k127_915234_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000002081 90.0
PYH1_k127_921956_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 595.0
PYH1_k127_921956_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000006281 219.0
PYH1_k127_921956_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000003048 151.0
PYH1_k127_958813_0 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 349.0
PYH1_k127_958813_1 - - - - 0.000000000000000000000004324 106.0
PYH1_k127_958813_2 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000002643 96.0
PYH1_k127_974385_0 Heat shock 70 kDa protein K04043 - - 0.0 1006.0
PYH1_k127_974385_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0001907 45.0