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Overview

ID MAG03154
Name PYH1_bin.49
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus Palsa-1315
Species
Assembly information
Completeness (%) 82.91
Contamination (%) 5.78
GC content (%) 57.0
N50 (bp) 4,243
Genome size (bp) 3,583,065

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3431

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1001681_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000001547 203.0
PYH1_k127_1001681_1 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.000000000000000000000000001047 115.0
PYH1_k127_1001681_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000008213 82.0
PYH1_k127_1004297_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000008392 201.0
PYH1_k127_1004297_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000001514 106.0
PYH1_k127_1006733_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.41e-284 886.0
PYH1_k127_1006733_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 499.0
PYH1_k127_1006733_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 493.0
PYH1_k127_1006733_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
PYH1_k127_1006733_4 SprT-like family K02742 - - 0.0000000000000000000000000000000000000000000000000000000002183 211.0
PYH1_k127_1006733_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000002554 192.0
PYH1_k127_100989_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 344.0
PYH1_k127_100989_1 Histidine kinase K20976 - - 0.0000000000000001869 81.0
PYH1_k127_1012_0 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 307.0
PYH1_k127_1012_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 297.0
PYH1_k127_1017059_0 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 1.299e-237 740.0
PYH1_k127_1017059_1 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000005553 157.0
PYH1_k127_1017459_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 507.0
PYH1_k127_1017565_0 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 467.0
PYH1_k127_1035534_0 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000308 112.0
PYH1_k127_1041970_0 radical SAM domain protein - - - 3.56e-225 699.0
PYH1_k127_1044062_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 582.0
PYH1_k127_1044062_1 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 492.0
PYH1_k127_1044062_2 nuclear chromosome segregation K02666,K03497,K19622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005642 278.0
PYH1_k127_1044062_3 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000002159 185.0
PYH1_k127_1044062_5 chemotaxis K02659,K03408,K03415,K11524 - - 0.000000000000000000000000000007584 124.0
PYH1_k127_1053385_0 alpha amylase, catalytic region - - - 6.343e-248 773.0
PYH1_k127_1053385_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 302.0
PYH1_k127_1059553_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 9.344e-232 724.0
PYH1_k127_1059553_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000007866 138.0
PYH1_k127_1068534_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
PYH1_k127_1068534_1 Cupin domain - - - 0.00000000004101 66.0
PYH1_k127_1068534_2 Helix-turn-helix domain - - - 0.000000007808 61.0
PYH1_k127_1074492_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.124e-212 665.0
PYH1_k127_1074492_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 377.0
PYH1_k127_1074492_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
PYH1_k127_1074492_3 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000002623 118.0
PYH1_k127_1077903_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 2.287e-266 830.0
PYH1_k127_1077903_1 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000000002042 217.0
PYH1_k127_1077903_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000001716 109.0
PYH1_k127_1077903_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000112 80.0
PYH1_k127_1086481_0 radical SAM domain protein - - - 0.0 1086.0
PYH1_k127_1086481_1 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
PYH1_k127_1086481_2 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001535 289.0
PYH1_k127_1086481_3 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000001083 225.0
PYH1_k127_1086481_4 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000001413 79.0
PYH1_k127_1088811_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 529.0
PYH1_k127_1088811_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002639 278.0
PYH1_k127_1088811_2 Phosphate acyltransferases K01897,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002088 252.0
PYH1_k127_1088811_3 - - - - 0.0000000000000000000000000000000000001092 144.0
PYH1_k127_1095629_0 transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 386.0
PYH1_k127_1097479_0 Integrase, catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 499.0
PYH1_k127_1097479_1 Transposase - - - 0.0000000000000000000000000000000000000000000000006228 176.0
PYH1_k127_1098557_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 351.0
PYH1_k127_1100423_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 496.0
PYH1_k127_1100423_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 385.0
PYH1_k127_1100423_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000000000000147 163.0
PYH1_k127_1100423_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000006501 154.0
PYH1_k127_1128451_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 6.606e-199 626.0
PYH1_k127_1128451_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 426.0
PYH1_k127_1128451_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000001996 53.0
PYH1_k127_1128451_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0001562 45.0
PYH1_k127_1128451_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
PYH1_k127_1128451_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001019 285.0
PYH1_k127_1128451_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
PYH1_k127_1128451_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000251 207.0
PYH1_k127_1128451_6 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000007039 205.0
PYH1_k127_1128451_7 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000001089 160.0
PYH1_k127_1128451_9 YGGT family K02221 - - 0.00000000000000000000000000000000000006205 148.0
PYH1_k127_1132704_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000005006 105.0
PYH1_k127_1136070_0 This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002866 281.0
PYH1_k127_1136070_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000001132 243.0
PYH1_k127_1136070_2 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.0000000000000000000000000000000000000000006583 164.0
PYH1_k127_1142059_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 499.0
PYH1_k127_1142059_1 pectinesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 351.0
PYH1_k127_1142059_2 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 288.0
PYH1_k127_1142059_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002242 272.0
PYH1_k127_1142059_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000001087 124.0
PYH1_k127_1144780_0 Proto-chlorophyllide reductase 57 kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 400.0
PYH1_k127_1144780_1 protein tyrosine kinase activity K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 288.0
PYH1_k127_1146686_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 409.0
PYH1_k127_1146686_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 353.0
PYH1_k127_1146686_2 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
PYH1_k127_1146686_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000003255 184.0
PYH1_k127_1146686_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000000000000007285 133.0
PYH1_k127_1146686_8 - - - - 0.000000000000135 73.0
PYH1_k127_1149120_0 Integrase, catalytic region - - - 1.029e-208 653.0
PYH1_k127_1155193_0 Histidine kinase K07638 - 2.7.13.3 8.066e-313 980.0
PYH1_k127_1155193_1 Histidine kinase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 259.0
PYH1_k127_1155193_2 Histidine kinase K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000268 228.0
PYH1_k127_1155193_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000002662 182.0
PYH1_k127_1155193_4 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000009086 98.0
PYH1_k127_1159057_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 395.0
PYH1_k127_1159057_1 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 353.0
PYH1_k127_1163624_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 439.0
PYH1_k127_1163624_1 Hemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 401.0
PYH1_k127_1164934_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.28e-230 715.0
PYH1_k127_1164934_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 4.378e-202 638.0
PYH1_k127_1164934_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 2.715e-200 629.0
PYH1_k127_1164934_3 NeuB family K03856 - 2.5.1.54 8.409e-200 624.0
PYH1_k127_1164934_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 555.0
PYH1_k127_1164934_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 548.0
PYH1_k127_1164934_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 435.0
PYH1_k127_1164934_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 299.0
PYH1_k127_1164934_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006961 282.0
PYH1_k127_1167761_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
PYH1_k127_1167761_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000004899 263.0
PYH1_k127_1167761_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000002288 174.0
PYH1_k127_1167761_4 coenzyme binding K07071 - - 0.000000000000000001188 88.0
PYH1_k127_117077_0 PFAM amine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 440.0
PYH1_k127_1175621_0 Transposase K07494 - - 0.000000000000000000000000000000000000000000000000000009023 195.0
PYH1_k127_1175621_1 Transposase - - - 0.0000000000000000000000000000000000567 141.0
PYH1_k127_1180660_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 530.0
PYH1_k127_1180660_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 443.0
PYH1_k127_1185365_0 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000001113 166.0
PYH1_k127_1185365_1 Sel1-like repeats. - - - 0.00000000000000000000000000000000001019 146.0
PYH1_k127_1192422_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 318.0
PYH1_k127_1192422_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001362 267.0
PYH1_k127_1192422_2 - - - - 0.000000000000000000003097 100.0
PYH1_k127_1223393_0 Hsp70 protein K04043,K04044 - - 1.791e-291 904.0
PYH1_k127_1223393_1 DnaJ molecular chaperone homology domain K04082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 285.0
PYH1_k127_1223393_2 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000000000000000000000000000000002155 182.0
PYH1_k127_1238352_0 PAS sensor protein K13243 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008144,GO:0008150,GO:0009628,GO:0016787,GO:0016788,GO:0019825,GO:0019826,GO:0020037,GO:0036094,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0070482,GO:0071111,GO:0097159,GO:1901363 3.1.4.52 1.974e-304 963.0
PYH1_k127_1238352_1 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 430.0
PYH1_k127_1238352_2 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 407.0
PYH1_k127_1238352_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001286 156.0
PYH1_k127_1238352_4 Phosphate acyltransferases - - - 0.0000000000000000000000001474 115.0
PYH1_k127_1238352_5 response regulator - - - 0.0000000000000002606 86.0
PYH1_k127_1238352_7 Histidine kinase - - - 0.00000002983 58.0
PYH1_k127_1238352_8 cheY-homologous receiver domain - - - 0.000009527 51.0
PYH1_k127_1254619_0 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001634 283.0
PYH1_k127_1254619_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000002292 72.0
PYH1_k127_1259566_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 560.0
PYH1_k127_1259566_1 - - - - 0.00000000000000000000000000000000000000000000000009813 180.0
PYH1_k127_1259566_2 - - - - 0.0000002883 58.0
PYH1_k127_1265466_0 dehydratase K04113 - 1.3.7.8 0.00000001207 66.0
PYH1_k127_127028_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 502.0
PYH1_k127_127028_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000008765 192.0
PYH1_k127_1278635_0 Hep Hag repeat protein - - - 0.00000000000002378 83.0
PYH1_k127_1278635_1 - - - - 0.00000007736 54.0
PYH1_k127_1286018_0 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 502.0
PYH1_k127_1287074_0 COG3335 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
PYH1_k127_1287074_1 Helix-turn-helix domain - - - 0.0000000000000000000000000563 112.0
PYH1_k127_1294615_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 460.0
PYH1_k127_1294615_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 306.0
PYH1_k127_1330160_0 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 524.0
PYH1_k127_1330160_1 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000001674 140.0
PYH1_k127_1332541_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 608.0
PYH1_k127_1332541_1 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 311.0
PYH1_k127_1332541_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
PYH1_k127_1332541_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
PYH1_k127_1334641_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 331.0
PYH1_k127_1334641_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000001383 158.0
PYH1_k127_1347256_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000536 187.0
PYH1_k127_1347256_1 PFAM Transposase, IS4-like - - - 0.00000000000000000000000001087 122.0
PYH1_k127_1347256_2 - - - - 0.000000003272 62.0
PYH1_k127_1354425_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009747 263.0
PYH1_k127_1358824_0 RNA-directed DNA polymerase (reverse transcriptase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003329 287.0
PYH1_k127_1358824_1 EthD domain - - - 0.00000000000000000000000000008703 117.0
PYH1_k127_1371390_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 474.0
PYH1_k127_1371390_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000001098 105.0
PYH1_k127_137191_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
PYH1_k127_137191_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000006471 221.0
PYH1_k127_1373154_0 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 574.0
PYH1_k127_1373154_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 469.0
PYH1_k127_1373154_2 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 446.0
PYH1_k127_1373154_3 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
PYH1_k127_1373154_4 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 305.0
PYH1_k127_1373154_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000227 243.0
PYH1_k127_1373154_6 Peptidoglycan-synthase activator LpoB K07337 - - 0.0000000000000000000000000000004139 122.0
PYH1_k127_1382424_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
PYH1_k127_1382424_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 328.0
PYH1_k127_1382424_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000001649 142.0
PYH1_k127_1406617_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 463.0
PYH1_k127_1406617_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000002299 96.0
PYH1_k127_1424509_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000006562 192.0
PYH1_k127_1424509_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000002418 177.0
PYH1_k127_1424509_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000008708 116.0
PYH1_k127_1442560_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000001699 164.0
PYH1_k127_1462882_0 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 286.0
PYH1_k127_1462882_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000005112 177.0
PYH1_k127_1462882_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000114 142.0
PYH1_k127_1462882_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000007388 100.0
PYH1_k127_1496765_0 Cytochrome c K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004994 269.0
PYH1_k127_1496765_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000004976 175.0
PYH1_k127_1496765_3 PFAM Membrane protein of K08972 - - 0.0000000000000002466 84.0
PYH1_k127_1518440_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 466.0
PYH1_k127_1518440_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 369.0
PYH1_k127_1528498_0 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 392.0
PYH1_k127_1528498_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 362.0
PYH1_k127_1538771_0 Elements of external origin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 445.0
PYH1_k127_1538771_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000007632 228.0
PYH1_k127_1538771_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000001114 144.0
PYH1_k127_1538771_3 domain protein - - - 0.0000000000000001112 85.0
PYH1_k127_1538771_4 Sel1-like repeats. K07126 - - 0.0000000588 56.0
PYH1_k127_1548706_0 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 334.0
PYH1_k127_155316_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
PYH1_k127_155316_1 Dodecin K09165 - - 0.000000000000000000008799 93.0
PYH1_k127_155316_2 Signal transduction protein with CBS domains - - - 0.00000006976 58.0
PYH1_k127_15659_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.986e-230 718.0
PYH1_k127_159051_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.039e-228 713.0
PYH1_k127_159051_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000001896 176.0
PYH1_k127_1611871_0 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 293.0
PYH1_k127_1611871_1 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000003825 205.0
PYH1_k127_1611871_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000008195 91.0
PYH1_k127_1611871_3 - - - - 0.00000000006606 64.0
PYH1_k127_1623603_0 ORF6N domain - - - 0.000000000000000000003314 96.0
PYH1_k127_1623603_1 ORF6N domain - - - 0.0000000000000000006558 88.0
PYH1_k127_1623673_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 346.0
PYH1_k127_1623673_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009295 242.0
PYH1_k127_1623673_4 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000001033 237.0
PYH1_k127_1623673_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000007718 215.0
PYH1_k127_1623673_6 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000001781 116.0
PYH1_k127_166431_0 - - - - 0.00000000000000000000000000000000000000000000007713 169.0
PYH1_k127_166431_1 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000001218 165.0
PYH1_k127_166431_2 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000000001607 119.0
PYH1_k127_166431_3 - - - - 0.0000000000000000000000004469 108.0
PYH1_k127_166431_4 Unextendable partial coding region - - - 0.0000000000001622 74.0
PYH1_k127_1678017_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.815e-244 760.0
PYH1_k127_1678017_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 291.0
PYH1_k127_1678017_10 RNase_H superfamily K07502 - - 0.000000000000000005171 85.0
PYH1_k127_1678017_11 - - - - 0.000000002131 61.0
PYH1_k127_1678017_2 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000009824 244.0
PYH1_k127_1678017_3 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000000000001656 201.0
PYH1_k127_1678017_4 - - - - 0.00000000000000000000000000000000000000000000000001737 184.0
PYH1_k127_1678017_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000005009 156.0
PYH1_k127_1678017_7 Glycoprotease family K14742 - - 0.000000000000000000000000002273 115.0
PYH1_k127_1678017_8 Protein of unknown function (DUF507) - - - 0.000000000000000000000000006982 112.0
PYH1_k127_1678017_9 Protein of unknown function (DUF507) - - - 0.00000000000000000000000004675 110.0
PYH1_k127_1678783_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.235e-304 943.0
PYH1_k127_1678783_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.562e-299 921.0
PYH1_k127_1678783_10 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000005788 146.0
PYH1_k127_1678783_11 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.000000000000000000000000000000000005064 141.0
PYH1_k127_1678783_12 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000623 144.0
PYH1_k127_1678783_13 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000000000003372 128.0
PYH1_k127_1678783_14 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000002656 112.0
PYH1_k127_1678783_15 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001058 63.0
PYH1_k127_1678783_16 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000002106 63.0
PYH1_k127_1678783_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.596e-217 687.0
PYH1_k127_1678783_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 523.0
PYH1_k127_1678783_4 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 519.0
PYH1_k127_1678783_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 484.0
PYH1_k127_1678783_6 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 363.0
PYH1_k127_1678783_7 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 289.0
PYH1_k127_1678783_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000001131 242.0
PYH1_k127_1678783_9 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000003543 169.0
PYH1_k127_1683491_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 473.0
PYH1_k127_1683491_1 Pfam:DUF989 - - - 0.0000000000000000000000000000000001188 136.0
PYH1_k127_1683666_0 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000002042 200.0
PYH1_k127_1683666_1 PFAM ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000002812 181.0
PYH1_k127_1683666_10 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000005579 72.0
PYH1_k127_1683666_11 RNase_H superfamily - - - 0.0000001691 59.0
PYH1_k127_1683666_12 gluconolactonase activity - - - 0.000003125 59.0
PYH1_k127_1683666_13 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K06919,K17680 - 3.6.4.12 0.00002028 56.0
PYH1_k127_1683666_14 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000029 57.0
PYH1_k127_1683666_15 lipolytic protein G-D-S-L family - - - 0.00004516 56.0
PYH1_k127_1683666_16 - - - - 0.0002066 54.0
PYH1_k127_1683666_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000005455 106.0
PYH1_k127_1683666_3 - - - - 0.00000000000000000003596 101.0
PYH1_k127_1683666_4 Gene 88 protein - - - 0.0000000000000000002168 97.0
PYH1_k127_1683666_5 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000003633 89.0
PYH1_k127_1683666_6 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000001977 93.0
PYH1_k127_1683666_7 - K06909 - - 0.000000000000001484 91.0
PYH1_k127_1683666_8 - - - - 0.0000000000006942 78.0
PYH1_k127_1683666_9 - - - - 0.00000000008134 69.0
PYH1_k127_1691624_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 329.0
PYH1_k127_1691624_1 CoA-ligase K01902 - 6.2.1.5 0.0000000000000000000000000000000000004098 140.0
PYH1_k127_1696071_0 PilZ domain K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 394.0
PYH1_k127_1699437_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 2.695e-238 742.0
PYH1_k127_1699437_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000001399 217.0
PYH1_k127_1700746_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
PYH1_k127_1700746_1 IMG reference gene - - - 0.000000000000007574 79.0
PYH1_k127_1702103_0 Iron-sulfur cluster-binding domain K06871 - - 1.16e-220 690.0
PYH1_k127_1702103_1 AAA domain K07133 - - 0.00000002403 55.0
PYH1_k127_1704751_0 Belongs to the binding-protein-dependent transport system permease family K01998,K11955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 323.0
PYH1_k127_1704751_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001031 252.0
PYH1_k127_1713857_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 376.0
PYH1_k127_1713857_1 - - - - 0.00000000000000000000000000000000000000000000000000000005357 199.0
PYH1_k127_1713857_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000852 169.0
PYH1_k127_1716096_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.762e-274 852.0
PYH1_k127_1716096_1 Type II/IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 471.0
PYH1_k127_1716096_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 401.0
PYH1_k127_1717365_0 chlorophyll binding K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 242.0
PYH1_k127_1717365_1 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000001364 109.0
PYH1_k127_1717365_2 PFAM YcfA-like protein - - - 0.000000000000000000009818 94.0
PYH1_k127_1717365_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000001384 62.0
PYH1_k127_1718619_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.562e-196 621.0
PYH1_k127_1719789_0 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000003698 216.0
PYH1_k127_1719789_1 Transposase - - - 0.00000000000000000000000001252 115.0
PYH1_k127_1719789_2 MlaC protein K07323 - - 0.00002835 52.0
PYH1_k127_1730721_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 484.0
PYH1_k127_1730721_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 336.0
PYH1_k127_1730721_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.00000000000000000000000002141 112.0
PYH1_k127_1734527_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 422.0
PYH1_k127_1734527_1 Protein of unknown function DUF126 K09123,K09128 - - 0.0000000000000000000000000000000000003966 144.0
PYH1_k127_1734527_2 Protein of unknown function (DUF521) K09123 - - 0.000000001593 59.0
PYH1_k127_1737891_0 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000002638 186.0
PYH1_k127_1737891_1 PFAM YhhN family protein - - - 0.000000001341 66.0
PYH1_k127_1741290_0 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 486.0
PYH1_k127_1741290_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000002246 181.0
PYH1_k127_1741290_2 Amidohydrolase family - - - 0.00000000000002261 74.0
PYH1_k127_1743525_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.41e-278 861.0
PYH1_k127_1743525_1 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 356.0
PYH1_k127_1743525_10 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000007378 178.0
PYH1_k127_1743525_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 349.0
PYH1_k127_1743525_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 330.0
PYH1_k127_1743525_4 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 329.0
PYH1_k127_1743525_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 321.0
PYH1_k127_1743525_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 301.0
PYH1_k127_1743525_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
PYH1_k127_1743525_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.0000000000000000000000000000000000000000000000000000000003747 209.0
PYH1_k127_1743525_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000003489 187.0
PYH1_k127_1743915_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 371.0
PYH1_k127_1743915_1 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000001501 192.0
PYH1_k127_1743915_10 Helix-hairpin-helix motif - - - 0.000001973 53.0
PYH1_k127_1743915_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000001194 160.0
PYH1_k127_1743915_3 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000002209 121.0
PYH1_k127_1743915_4 - - - - 0.000000000000000000000005637 104.0
PYH1_k127_1743915_6 - - - - 0.0000000000000000008529 92.0
PYH1_k127_1743915_7 Cytochrome c K12263 - - 0.0000000000000003626 84.0
PYH1_k127_1743915_8 Protein conserved in bacteria - - - 0.0000000000444 73.0
PYH1_k127_1743915_9 Belongs to the SOS response-associated peptidase family - - - 0.000000001674 62.0
PYH1_k127_1746676_0 L,D-transpeptidase catalytic domain K16291 - - 2.381e-202 638.0
PYH1_k127_1750160_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 353.0
PYH1_k127_1750160_1 2Fe-2S -binding domain K13483 - - 0.0000000000000000000000000000000000000000000001598 169.0
PYH1_k127_175639_0 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 391.0
PYH1_k127_175639_1 - - - - 0.0000000000000000000000000000000000000000000000000009464 187.0
PYH1_k127_1758151_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 8.273e-280 867.0
PYH1_k127_1758151_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.215e-209 657.0
PYH1_k127_1758151_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 562.0
PYH1_k127_1758151_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 551.0
PYH1_k127_1758151_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 484.0
PYH1_k127_1758151_5 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000006985 139.0
PYH1_k127_1759472_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000009361 186.0
PYH1_k127_1759472_1 Winged helix-turn helix - - - 0.000000003976 65.0
PYH1_k127_1759472_2 Serine aminopeptidase, S33 K06889 - - 0.000001371 51.0
PYH1_k127_1765792_1 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000000000000000000000571 170.0
PYH1_k127_1765792_2 phosphatase - - - 0.0000000000000000000000000000000000001256 146.0
PYH1_k127_1765792_3 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000001599 110.0
PYH1_k127_1769941_0 DNA polymerase K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 424.0
PYH1_k127_1769941_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000004554 67.0
PYH1_k127_1769941_2 - - - - 0.000946 44.0
PYH1_k127_1770315_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 411.0
PYH1_k127_1770315_2 Transposase - - - 0.0000000000000000000000000000000003137 138.0
PYH1_k127_1770315_3 DDE superfamily endonuclease - - - 0.000000000001923 76.0
PYH1_k127_177045_0 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 613.0
PYH1_k127_177045_2 HNH nucleases - - - 0.00002852 48.0
PYH1_k127_1772504_0 - - - - 0.000000000000000000000000000002894 124.0
PYH1_k127_1772504_1 Domain of unknown function (DUF4375) - - - 0.000000000000000000001347 101.0
PYH1_k127_1772693_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 416.0
PYH1_k127_1772693_1 transcriptional regulator with C-terminal CBS domains - - - 0.000000000000000000000000000000000000007354 146.0
PYH1_k127_1772693_2 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000002208 136.0
PYH1_k127_1772693_3 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000001559 113.0
PYH1_k127_1772693_4 Evidence 2b Function of strongly homologous gene - - - 0.00002025 51.0
PYH1_k127_1776683_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000002313 196.0
PYH1_k127_177963_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 434.0
PYH1_k127_177963_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 387.0
PYH1_k127_177963_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 333.0
PYH1_k127_177963_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000007817 148.0
PYH1_k127_177963_5 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000007807 118.0
PYH1_k127_177985_0 Evidence 2b Function of strongly homologous gene - - - 6.018e-210 656.0
PYH1_k127_177985_1 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 350.0
PYH1_k127_177985_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000003105 189.0
PYH1_k127_1780369_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 287.0
PYH1_k127_1780369_1 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000001426 192.0
PYH1_k127_1780369_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000005509 179.0
PYH1_k127_1780369_3 Protein of unknown function (DUF465) K09794 - - 0.000000000000000005032 87.0
PYH1_k127_1782018_0 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 320.0
PYH1_k127_1784549_0 transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 492.0
PYH1_k127_1784549_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 248.0
PYH1_k127_1794044_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.000000000000000000000000000000000000000000005746 181.0
PYH1_k127_1809799_0 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000003193 173.0
PYH1_k127_1809799_1 - - - - 0.00000000000000000000000000000000001143 139.0
PYH1_k127_1809799_3 - - - - 0.000002295 54.0
PYH1_k127_181315_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 609.0
PYH1_k127_181315_1 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 434.0
PYH1_k127_181315_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 402.0
PYH1_k127_1814777_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 377.0
PYH1_k127_1819248_0 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000005099 226.0
PYH1_k127_1819248_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000659 146.0
PYH1_k127_1819248_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000002828 111.0
PYH1_k127_1819248_3 dephospho-CoA kinase activity - - - 0.0000000003991 68.0
PYH1_k127_1819248_4 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 0.00001025 54.0
PYH1_k127_1819248_5 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0001057 49.0
PYH1_k127_1819248_6 Transcriptional regulator - - - 0.0001663 48.0
PYH1_k127_1829843_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1651.0
PYH1_k127_1829843_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 567.0
PYH1_k127_1829843_4 Cytochrome P450 - - - 0.00000003734 60.0
PYH1_k127_1830545_0 Type II/IV secretion system protein K02669 - - 4.294e-201 632.0
PYH1_k127_1830545_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 488.0
PYH1_k127_1830545_2 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 482.0
PYH1_k127_1830545_3 cell envelope organization K05807,K08309 - - 0.0000000000000128 76.0
PYH1_k127_1831_0 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 481.0
PYH1_k127_1831_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 457.0
PYH1_k127_1831_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000003811 129.0
PYH1_k127_1832730_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002667 273.0
PYH1_k127_1832730_2 AntiSigma factor - - - 0.000000000000000000000001663 106.0
PYH1_k127_1832730_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000004453 61.0
PYH1_k127_1838739_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 456.0
PYH1_k127_1838739_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 453.0
PYH1_k127_1838739_2 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 380.0
PYH1_k127_1841272_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 482.0
PYH1_k127_1841272_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 390.0
PYH1_k127_1841272_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000001483 198.0
PYH1_k127_1841272_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000009463 92.0
PYH1_k127_1841272_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000002039 64.0
PYH1_k127_1841272_5 Alpha-beta hydrolase superfamily - - - 0.00003785 56.0
PYH1_k127_1841736_0 Transposase K00957,K07497 - 2.7.7.4 0.000000000000001009 89.0
PYH1_k127_1847465_0 6-phosphogluconolactonase activity - - - 0.00000000000000000004175 107.0
PYH1_k127_1851447_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 402.0
PYH1_k127_1851447_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000003703 132.0
PYH1_k127_1851712_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001759 265.0
PYH1_k127_1851712_1 Peptidase family M1 domain K08776 - - 0.000000000000000000000000000000000000000000000000000001367 200.0
PYH1_k127_1853501_0 Transposase and inactivated derivatives IS30 family - - - 0.000000000000000000000006456 102.0
PYH1_k127_1853501_1 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000004634 100.0
PYH1_k127_1853501_3 PFAM nuclease (SNase domain protein) - - - 0.0000000001101 64.0
PYH1_k127_1853501_8 ribonuclease activity - - - 0.00003745 46.0
PYH1_k127_1857801_0 Transposase DDE domain K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000183 235.0
PYH1_k127_1857801_1 - - - - 0.00000000000000000000000000000008356 127.0
PYH1_k127_1857801_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000002566 59.0
PYH1_k127_1861775_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 581.0
PYH1_k127_1861775_1 cobalamin binding K21089,K21972,K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 313.0
PYH1_k127_1861775_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002991 271.0
PYH1_k127_1861775_3 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000000003349 96.0
PYH1_k127_1876812_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000001895 210.0
PYH1_k127_1876812_1 Belongs to the GcvT family K00605 - 2.1.2.10 0.0000000000000000000000000000001286 128.0
PYH1_k127_1881847_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 7.865e-238 739.0
PYH1_k127_1881847_1 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000008805 211.0
PYH1_k127_1887719_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.286e-222 694.0
PYH1_k127_1887719_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 515.0
PYH1_k127_1887719_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 478.0
PYH1_k127_1887719_3 Class ii aldolase K01628,K18847 - 2.2.1.8,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 381.0
PYH1_k127_1887719_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 377.0
PYH1_k127_1887719_5 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000004762 245.0
PYH1_k127_1887719_6 Protein of unknown function (DUF3703) - - - 0.0000000000000000000000000000000000001973 143.0
PYH1_k127_1887719_7 - - - - 0.000000000000000000000001056 108.0
PYH1_k127_1887719_8 - - - - 0.000002355 56.0
PYH1_k127_189358_0 PFAM MULE transposase, conserved domain - - - 0.00000000000000000000000000000000000000000001398 176.0
PYH1_k127_1894548_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 7.285e-272 844.0
PYH1_k127_1894548_1 4Fe-4S dicluster domain - - - 0.0002964 44.0
PYH1_k127_189865_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 532.0
PYH1_k127_189865_1 response to pH - - - 0.00000000000000000000000000000000000003761 150.0
PYH1_k127_189865_2 - - - - 0.00000000000000000000001626 101.0
PYH1_k127_189865_3 Alpha amylase catalytic - - - 0.0000001009 53.0
PYH1_k127_1907576_1 SPTR CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000000000000004837 123.0
PYH1_k127_1907576_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000001092 120.0
PYH1_k127_1907576_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000003471 82.0
PYH1_k127_1909123_0 Arylsulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 332.0
PYH1_k127_1909123_1 Sulfatase - - - 0.00000000000000000000000000000000000000000002842 168.0
PYH1_k127_1911733_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 422.0
PYH1_k127_1911733_1 spore germination K03605 - - 0.0000000000000000000000000177 119.0
PYH1_k127_1911733_2 nickel cation binding K04651 - - 0.000001475 55.0
PYH1_k127_1916333_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 342.0
PYH1_k127_1916333_1 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000001124 172.0
PYH1_k127_1916333_3 HNH nucleases - - - 0.00000007699 56.0
PYH1_k127_1920482_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2735.0
PYH1_k127_1920482_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 559.0
PYH1_k127_1920482_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 520.0
PYH1_k127_1924533_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.745e-199 632.0
PYH1_k127_1924533_2 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000004873 196.0
PYH1_k127_1924533_3 response regulator - - - 0.000000000000282 76.0
PYH1_k127_1926127_0 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 588.0
PYH1_k127_1927044_0 Transposase zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
PYH1_k127_1927044_1 - - - - 0.00000000000000000000000000000000000000000000004313 175.0
PYH1_k127_1927044_2 Transposase and inactivated derivatives - - - 0.00000000000000000001446 97.0
PYH1_k127_1931504_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 596.0
PYH1_k127_1931504_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007842 257.0
PYH1_k127_1931504_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000001791 169.0
PYH1_k127_1931504_3 Putative prokaryotic signal transducing protein - - - 0.0000000000000000004688 92.0
PYH1_k127_1931504_4 Protein of unknown function (DUF3703) - - - 0.000000002415 60.0
PYH1_k127_1937457_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.678e-237 738.0
PYH1_k127_1937457_1 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 558.0
PYH1_k127_1937457_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 436.0
PYH1_k127_1937457_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000445 228.0
PYH1_k127_1937457_4 response regulator, receiver K02479 - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
PYH1_k127_1937457_5 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002564 199.0
PYH1_k127_1941989_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
PYH1_k127_1941989_1 phosphoprotein phosphatase activity K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 327.0
PYH1_k127_1941989_2 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
PYH1_k127_1941989_3 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000000000000000000000000000000001046 183.0
PYH1_k127_1941989_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000003813 125.0
PYH1_k127_194461_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.454e-255 797.0
PYH1_k127_194461_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 483.0
PYH1_k127_194461_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 434.0
PYH1_k127_194461_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 310.0
PYH1_k127_194461_4 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000000000000000001754 116.0
PYH1_k127_194461_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000001147 59.0
PYH1_k127_1947502_0 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 363.0
PYH1_k127_1947502_1 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 314.0
PYH1_k127_1947502_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0004263 51.0
PYH1_k127_1951100_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 480.0
PYH1_k127_1951100_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 357.0
PYH1_k127_1954810_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 417.0
PYH1_k127_196026_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 336.0
PYH1_k127_196029_0 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 447.0
PYH1_k127_196029_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 339.0
PYH1_k127_196029_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
PYH1_k127_1962141_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 3.393e-275 857.0
PYH1_k127_1962141_1 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 384.0
PYH1_k127_1962141_10 Sigma-54 interaction domain K07714 - - 0.0000000000000006218 77.0
PYH1_k127_1962141_11 ACT domain - - - 0.0000002158 56.0
PYH1_k127_1962141_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 365.0
PYH1_k127_1962141_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 308.0
PYH1_k127_1962141_4 cellular manganese ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000001435 227.0
PYH1_k127_1962141_6 integral membrane protein - - - 0.000000000000000000000000000000000000005054 151.0
PYH1_k127_1962141_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000003249 146.0
PYH1_k127_1962141_8 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000008187 158.0
PYH1_k127_1962141_9 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000007077 95.0
PYH1_k127_1963491_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 514.0
PYH1_k127_197075_0 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K07444,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 437.0
PYH1_k127_197075_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 283.0
PYH1_k127_197075_2 ADP-Ribose Pyrophosphatase - - - 0.00000000001201 67.0
PYH1_k127_1976349_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 573.0
PYH1_k127_1976349_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 427.0
PYH1_k127_1976349_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 423.0
PYH1_k127_1976349_3 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 287.0
PYH1_k127_1976349_5 Transposase - - - 0.00000000000000000000000000002382 124.0
PYH1_k127_1976349_6 PFAM Integrase catalytic region - - - 0.0000000000000000001007 97.0
PYH1_k127_1979855_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 573.0
PYH1_k127_1979855_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004164 258.0
PYH1_k127_1979855_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000834 161.0
PYH1_k127_1984300_0 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 524.0
PYH1_k127_1984300_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 298.0
PYH1_k127_1984300_3 - - - - 0.0000000000000000000000004782 114.0
PYH1_k127_1984337_0 Nadh flavin oxidoreductase nadh oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 479.0
PYH1_k127_1984337_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007006 276.0
PYH1_k127_1984337_2 - - - - 0.00003453 46.0
PYH1_k127_1984337_3 COGs COG3293 - - - 0.0002223 43.0
PYH1_k127_1991015_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.114e-283 878.0
PYH1_k127_1991015_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000001115 77.0
PYH1_k127_1991015_4 - - - - 0.0004566 43.0
PYH1_k127_199546_0 Sulfatase K01130 - 3.1.6.1 3.648e-320 987.0
PYH1_k127_199546_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004115 226.0
PYH1_k127_199546_2 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000000000001808 221.0
PYH1_k127_199546_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000001301 147.0
PYH1_k127_199546_4 NmrA-like family - - - 0.00000934 48.0
PYH1_k127_1999660_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 576.0
PYH1_k127_1999660_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000002449 105.0
PYH1_k127_2016176_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 7.638e-226 703.0
PYH1_k127_2036395_0 heat shock protein binding - - - 2.682e-216 686.0
PYH1_k127_2036395_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003464 251.0
PYH1_k127_2036395_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007038 246.0
PYH1_k127_2036395_3 photosynthesis K02453,K02660 - - 0.000000000000000000000000000000000000000000000000000007802 202.0
PYH1_k127_2050307_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 363.0
PYH1_k127_2050307_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006016 264.0
PYH1_k127_207496_0 ATPase, AAA K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 447.0
PYH1_k127_207496_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
PYH1_k127_207496_2 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 326.0
PYH1_k127_207496_3 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000004329 208.0
PYH1_k127_207496_4 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000000000000000000000000000000003467 201.0
PYH1_k127_207496_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000001008 201.0
PYH1_k127_207496_7 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000000000000000000000000000000000000000006834 180.0
PYH1_k127_2081492_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 367.0
PYH1_k127_2081492_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000002929 171.0
PYH1_k127_2081492_2 DRTGG domain - - - 0.000000000237 66.0
PYH1_k127_2082213_0 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001063 294.0
PYH1_k127_2082213_1 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005737 224.0
PYH1_k127_2082213_2 - - - - 0.000000000000000005823 88.0
PYH1_k127_2091451_0 transposase K07492 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
PYH1_k127_2092860_0 HTH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 386.0
PYH1_k127_2092860_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 291.0
PYH1_k127_2092860_2 Transposase - - - 0.000000000000000000000000000003079 122.0
PYH1_k127_2101198_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 496.0
PYH1_k127_2101198_1 Transposase - - - 0.000000000000000000000000000000000000000007217 156.0
PYH1_k127_2106954_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 393.0
PYH1_k127_2106954_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 291.0
PYH1_k127_2106954_2 Transposase - - - 0.0000000000000000000000000000001682 125.0
PYH1_k127_2106954_3 peptidase M42 - - - 0.00000000000000000000005105 104.0
PYH1_k127_2110293_0 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 553.0
PYH1_k127_2110293_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 490.0
PYH1_k127_2110293_2 protein secretion K03116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 317.0
PYH1_k127_2110293_3 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001173 268.0
PYH1_k127_2110293_4 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
PYH1_k127_2110293_5 PBS lyase HEAT-like repeat - - - 0.000000000004599 76.0
PYH1_k127_2132178_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 389.0
PYH1_k127_2132178_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 338.0
PYH1_k127_2132178_2 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 266.0
PYH1_k127_2132178_3 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000003553 226.0
PYH1_k127_2140877_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 606.0
PYH1_k127_2145429_0 Protein of unknown function (DUF1214) - - - 2.823e-213 664.0
PYH1_k127_214547_0 Cation transporter/ATPase, N-terminus - - - 3.152e-206 651.0
PYH1_k127_214547_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 530.0
PYH1_k127_214547_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000001596 109.0
PYH1_k127_2146736_0 iron dependent repressor K02003,K02565,K15545 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 509.0
PYH1_k127_214859_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 320.0
PYH1_k127_214859_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002213 243.0
PYH1_k127_214859_2 COG3335 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000008919 172.0
PYH1_k127_2154049_0 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 1.5e-323 996.0
PYH1_k127_2154049_1 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 3.231e-257 799.0
PYH1_k127_2154049_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 416.0
PYH1_k127_2154049_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000004969 203.0
PYH1_k127_2163526_0 denitrification pathway - - - 3.503e-209 654.0
PYH1_k127_2163526_1 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 584.0
PYH1_k127_2163526_3 TIGRFAM addiction module toxin, Txe YoeB family - - - 0.0000000000000000000000000000000001415 136.0
PYH1_k127_2163526_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000003357 123.0
PYH1_k127_2163526_5 Cupin domain - - - 0.0000000000000000000000000001711 121.0
PYH1_k127_2164568_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K03338 - 2.7.1.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 496.0
PYH1_k127_2164568_1 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 382.0
PYH1_k127_2164568_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 302.0
PYH1_k127_2164568_3 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
PYH1_k127_2164568_4 binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001023 275.0
PYH1_k127_2164568_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000000000000000000001083 166.0
PYH1_k127_2164568_6 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000846 162.0
PYH1_k127_2164568_7 Phospholipid methyltransferase - - - 0.0000000003156 68.0
PYH1_k127_216779_0 succinyl-diaminopimelate desuccinylase activity - - - 4.745e-256 794.0
PYH1_k127_216779_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 4.887e-214 676.0
PYH1_k127_216779_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 438.0
PYH1_k127_216779_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 417.0
PYH1_k127_216779_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 339.0
PYH1_k127_216779_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 307.0
PYH1_k127_216779_6 Protein of unknown function (DUF5131) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004738 253.0
PYH1_k127_216779_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000003412 205.0
PYH1_k127_216779_9 Protein of unknown function (DUF5131) - - - 0.0000000000000000000000004039 109.0
PYH1_k127_2172716_1 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000002747 160.0
PYH1_k127_2190677_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.415e-219 681.0
PYH1_k127_2190677_1 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000001809 186.0
PYH1_k127_2208506_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 451.0
PYH1_k127_2208506_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 444.0
PYH1_k127_2208506_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 425.0
PYH1_k127_2208506_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000009751 171.0
PYH1_k127_2208506_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000002451 136.0
PYH1_k127_2211225_0 reverse transcriptase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 441.0
PYH1_k127_2227673_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000001029 226.0
PYH1_k127_2227673_1 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000001292 91.0
PYH1_k127_2257402_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
PYH1_k127_2257402_1 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000007213 114.0
PYH1_k127_2260907_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 315.0
PYH1_k127_2260907_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001397 214.0
PYH1_k127_2260907_2 - - - - 0.000000000000000000000002609 106.0
PYH1_k127_2260907_3 - - - - 0.00000000000000000009498 94.0
PYH1_k127_2260907_4 PFAM HEPN domain - - - 0.00000004475 55.0
PYH1_k127_2262376_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 483.0
PYH1_k127_2262376_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000008124 76.0
PYH1_k127_230394_0 PFAM Transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 552.0
PYH1_k127_2308537_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 349.0
PYH1_k127_2308537_1 Lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 352.0
PYH1_k127_2308537_2 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 332.0
PYH1_k127_2367016_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0 1038.0
PYH1_k127_2367016_1 2 iron, 2 sulfur cluster binding K04487,K13643 - 2.8.1.7 0.000000000000000000000000000000000000000000000000003665 185.0
PYH1_k127_2367016_2 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000003299 173.0
PYH1_k127_2372060_0 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 312.0
PYH1_k127_2372060_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000002795 181.0
PYH1_k127_2373203_0 Phage integrase family - - - 0.00000000000000000000002317 113.0
PYH1_k127_2379980_0 PFAM Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 303.0
PYH1_k127_2379980_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000001296 87.0
PYH1_k127_2379980_2 - - - - 0.0000000002724 65.0
PYH1_k127_2379980_3 reverse transcriptase - - - 0.000001328 51.0
PYH1_k127_2379980_4 reverse transcriptase - - - 0.000005206 49.0
PYH1_k127_23969_0 peptidyl-tyrosine sulfation - - - 4.405e-221 698.0
PYH1_k127_23969_1 transmembrane transporter activity K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 454.0
PYH1_k127_23969_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000004679 235.0
PYH1_k127_23969_4 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000005378 142.0
PYH1_k127_2397668_0 hmm pf01609 - - - 0.00000000000000007211 93.0
PYH1_k127_240593_0 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 319.0
PYH1_k127_240593_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000001214 155.0
PYH1_k127_2406228_0 - - - - 0.000000000000000000000000001968 113.0
PYH1_k127_2406228_3 - - - - 0.000000000008185 66.0
PYH1_k127_24529_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.000000000000006716 87.0
PYH1_k127_2453211_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
PYH1_k127_2453211_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001625 276.0
PYH1_k127_247165_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 394.0
PYH1_k127_247165_1 Transposase - - - 0.00000000000000000000000000000000002231 137.0
PYH1_k127_2475371_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00982,K00990 - 2.7.7.42,2.7.7.59,2.7.7.89 2.242e-244 769.0
PYH1_k127_2475371_1 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000003901 72.0
PYH1_k127_2516884_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 309.0
PYH1_k127_2516884_1 PFAM Polysaccharide export protein - - - 0.00000000000000000000000000000000000000000000000000000000136 214.0
PYH1_k127_2516884_2 PFAM lipopolysaccharide biosynthesis - - - 0.000000000002524 70.0
PYH1_k127_2518292_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 540.0
PYH1_k127_2518292_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 383.0
PYH1_k127_2518292_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 387.0
PYH1_k127_2518292_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 285.0
PYH1_k127_2518292_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000003525 129.0
PYH1_k127_2518292_5 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000005774 119.0
PYH1_k127_2518971_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 450.0
PYH1_k127_2520996_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 391.0
PYH1_k127_2520996_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000002269 130.0
PYH1_k127_2521945_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 589.0
PYH1_k127_2521945_1 Replication initiation factor K07467 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 385.0
PYH1_k127_2521945_2 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 300.0
PYH1_k127_2521945_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000008899 174.0
PYH1_k127_2521945_4 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000004445 160.0
PYH1_k127_2521945_5 Cytochrome c K12263 - - 0.0000000000000000000000000000009519 126.0
PYH1_k127_2521945_7 DNA excision K02806 - - 0.000000000000000000000000004885 113.0
PYH1_k127_2524125_0 Glycosyl hydrolase family 57 - - - 0.0 1063.0
PYH1_k127_2524125_1 phosphorelay signal transduction system - - - 8.926e-205 646.0
PYH1_k127_2524125_10 mRNA binding K07339 - - 0.0000000001219 64.0
PYH1_k127_2524125_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 585.0
PYH1_k127_2524125_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 509.0
PYH1_k127_2524125_4 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 380.0
PYH1_k127_2524125_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 373.0
PYH1_k127_2524125_6 - - - - 0.000000000000000000000000000001057 125.0
PYH1_k127_2524125_7 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000005853 113.0
PYH1_k127_2524125_8 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000001899 108.0
PYH1_k127_2524125_9 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000009564 102.0
PYH1_k127_252733_0 Dehydratase family K01687 - 4.2.1.9 2.051e-244 758.0
PYH1_k127_252733_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 310.0
PYH1_k127_252733_2 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain K08372 - - 0.00000000000000000000008956 111.0
PYH1_k127_2530598_0 MacB-like periplasmic core domain K02004 - - 7.568e-266 844.0
PYH1_k127_2530598_1 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 514.0
PYH1_k127_2530598_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000003204 192.0
PYH1_k127_2530598_3 response regulator - - - 0.00000000000000000001288 94.0
PYH1_k127_2530598_4 lipoprotein transporter activity K02003 - - 0.00000008619 54.0
PYH1_k127_2532288_0 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 413.0
PYH1_k127_2532288_1 radical SAM domain protein K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 269.0
PYH1_k127_2532288_2 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000001741 257.0
PYH1_k127_2532288_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000006695 107.0
PYH1_k127_2532288_4 PFAM nuclease (SNase domain protein) - - - 0.00000001691 59.0
PYH1_k127_2532288_5 nuclease - - - 0.0009538 45.0
PYH1_k127_254054_0 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000000000000001817 214.0
PYH1_k127_254054_1 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000004335 147.0
PYH1_k127_254054_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000004703 129.0
PYH1_k127_254054_3 SpoIIAA-like - - - 0.000000000000000000000000005548 113.0
PYH1_k127_254054_4 Mechanosensitive ion channel K16052,K22044 - - 0.0000007653 56.0
PYH1_k127_2546247_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 559.0
PYH1_k127_2546247_1 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 315.0
PYH1_k127_2549626_0 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 454.0
PYH1_k127_2549626_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 288.0
PYH1_k127_2549626_2 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
PYH1_k127_2549626_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001382 281.0
PYH1_k127_2549626_4 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000009434 123.0
PYH1_k127_2550161_0 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 413.0
PYH1_k127_2550161_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000008958 264.0
PYH1_k127_2550161_2 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000149 224.0
PYH1_k127_2550161_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000158 44.0
PYH1_k127_2557727_1 Sulfatase K01130 - 3.1.6.1 0.0000000000000003155 85.0
PYH1_k127_256070_0 reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000001192 241.0
PYH1_k127_2563087_0 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000001091 214.0
PYH1_k127_2563087_1 Transposase K07483 - - 0.000000000000000000000000000426 116.0
PYH1_k127_2576019_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 351.0
PYH1_k127_2576019_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000009806 177.0
PYH1_k127_2576019_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002358 153.0
PYH1_k127_2579002_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 414.0
PYH1_k127_2579002_1 region 4 type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 268.0
PYH1_k127_2579002_2 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000002371 234.0
PYH1_k127_2579002_3 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000000000001538 231.0
PYH1_k127_2579002_4 - - - - 0.0000000000000000000000003436 109.0
PYH1_k127_2579002_5 - - - - 0.0000000000000000000017 100.0
PYH1_k127_2579002_6 - - - - 0.0000000000000000001616 94.0
PYH1_k127_2579002_7 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000006818 69.0
PYH1_k127_2592045_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.597e-253 783.0
PYH1_k127_2592045_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000001131 171.0
PYH1_k127_259441_0 Pup-ligase protein K13571 - 6.3.1.19 4.381e-242 755.0
PYH1_k127_259441_1 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 426.0
PYH1_k127_2596428_0 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000002987 155.0
PYH1_k127_2596428_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000002596 78.0
PYH1_k127_2596428_3 - - - - 0.00001857 47.0
PYH1_k127_2596458_0 Sulfatase K01130 - 3.1.6.1 1.319e-277 858.0
PYH1_k127_2596458_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000004115 170.0
PYH1_k127_2596458_2 BON domain - - - 0.0000000000000000000000000000000000006548 143.0
PYH1_k127_2596458_3 - - - - 0.0000000000000002944 79.0
PYH1_k127_2612334_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.335e-202 646.0
PYH1_k127_2623820_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 283.0
PYH1_k127_2623820_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000002317 155.0
PYH1_k127_2623820_2 Zinc-binding dehydrogenase K13979 - - 0.0000000000000000000003186 96.0
PYH1_k127_2623820_3 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.000000000000001256 78.0
PYH1_k127_2627292_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 421.0
PYH1_k127_2627292_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000005429 139.0
PYH1_k127_2638704_0 xylulokinase activity K00854 - 2.7.1.17 5.807e-305 939.0
PYH1_k127_2638704_2 - - - - 0.0000000000000000000000000000000000005831 143.0
PYH1_k127_2642570_0 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
PYH1_k127_2642570_1 Copper-containing nitrite reductase K00368 - 1.7.2.1 0.0000001295 57.0
PYH1_k127_2651382_0 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000002391 241.0
PYH1_k127_2651382_1 Integrase catalytic - - - 0.000000947 59.0
PYH1_k127_2656240_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.826e-282 873.0
PYH1_k127_2656240_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00982,K00990 - 2.7.7.42,2.7.7.59,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 395.0
PYH1_k127_2659500_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000006421 225.0
PYH1_k127_2662510_0 transport system permease K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 312.0
PYH1_k127_2662510_1 'ABC-type branched-chain amino acid transport K01999,K11954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 306.0
PYH1_k127_2662510_2 PFAM Branched-chain amino acid transport system permease component K01998,K11955 - - 0.00000000000000000000000000000000000000000008252 165.0
PYH1_k127_2662510_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.000000000000006312 75.0
PYH1_k127_2669494_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001729 256.0
PYH1_k127_2669494_1 CRISPR-associated protein (Cas_Cas5) K19119 - - 0.00000000000006845 74.0
PYH1_k127_2680089_0 COG NOG14600 non supervised orthologous group - - - 0.00000000009301 63.0
PYH1_k127_2680089_1 - - - - 0.000000006336 59.0
PYH1_k127_2689701_0 AcrB/AcrD/AcrF family - - - 3.243e-248 772.0
PYH1_k127_2689701_2 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 475.0
PYH1_k127_2689701_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000000000001495 196.0
PYH1_k127_2689701_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000002852 169.0
PYH1_k127_2689701_6 Sterol carrier protein - - - 0.0000000000000000000000000000000000000000101 156.0
PYH1_k127_2689701_8 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.0009359 48.0
PYH1_k127_2693055_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000006376 226.0
PYH1_k127_2693949_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 423.0
PYH1_k127_2693967_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 419.0
PYH1_k127_2696488_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 350.0
PYH1_k127_2702433_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 490.0
PYH1_k127_2702433_1 peptide catabolic process - - - 0.000000000000000000000000000386 115.0
PYH1_k127_2705294_0 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000285 177.0
PYH1_k127_2705294_1 SnoaL-like domain K06893 - - 0.00000000000000000000000000000000000000000007115 166.0
PYH1_k127_2705294_2 - - - - 0.00000000000000000000000000000000247 132.0
PYH1_k127_2705294_3 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000004169 86.0
PYH1_k127_2707429_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 484.0
PYH1_k127_2707429_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 406.0
PYH1_k127_2707429_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000007006 62.0
PYH1_k127_2707554_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000007835 173.0
PYH1_k127_2709073_0 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 317.0
PYH1_k127_2711087_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1106.0
PYH1_k127_2711087_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 486.0
PYH1_k127_2711087_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000004482 241.0
PYH1_k127_2711087_3 Thioredoxin-like domain K03671 - - 0.0001485 45.0
PYH1_k127_2711497_0 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 395.0
PYH1_k127_2713133_0 Transposase IS116 IS110 IS902 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 514.0
PYH1_k127_2713133_1 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 368.0
PYH1_k127_2713243_0 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 490.0
PYH1_k127_2713243_1 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
PYH1_k127_2713243_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.00000000000000000000000000000000000000000000000003322 183.0
PYH1_k127_2730233_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 7.808e-279 862.0
PYH1_k127_2730233_1 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 419.0
PYH1_k127_2742521_0 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 302.0
PYH1_k127_2742521_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000002135 243.0
PYH1_k127_2742521_3 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000000000000458 157.0
PYH1_k127_2742521_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000001119 70.0
PYH1_k127_2742521_5 Tfp pilus assembly protein FimV - - - 0.00001333 59.0
PYH1_k127_2745864_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006125 183.0
PYH1_k127_2745864_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000001147 139.0
PYH1_k127_2749046_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 1.588e-232 728.0
PYH1_k127_2749046_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 387.0
PYH1_k127_2749046_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 308.0
PYH1_k127_2756312_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1520.0
PYH1_k127_2756312_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 376.0
PYH1_k127_2756312_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 368.0
PYH1_k127_2756312_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 325.0
PYH1_k127_2756312_4 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000001293 77.0
PYH1_k127_2760560_0 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 284.0
PYH1_k127_2760560_1 - - - - 0.000000000000000000000000000000000046 134.0
PYH1_k127_2768835_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 397.0
PYH1_k127_2768835_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000004545 185.0
PYH1_k127_2774247_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 441.0
PYH1_k127_2774247_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004419 281.0
PYH1_k127_2775756_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 391.0
PYH1_k127_2783364_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 461.0
PYH1_k127_2791629_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1501.0
PYH1_k127_2791629_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1258.0
PYH1_k127_2791629_2 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.397e-282 876.0
PYH1_k127_2791629_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 311.0
PYH1_k127_2791629_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003865 248.0
PYH1_k127_2791629_5 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000001395 184.0
PYH1_k127_2803060_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 569.0
PYH1_k127_2803060_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000888 270.0
PYH1_k127_2807540_0 anaerobic respiration K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 1.212e-279 869.0
PYH1_k127_2807540_1 Protein involved in outer membrane biogenesis K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 604.0
PYH1_k127_2807540_2 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 403.0
PYH1_k127_2807540_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 368.0
PYH1_k127_2807540_4 to Cytochrome c-554 precursor (C554) (Hydroxylamine oxidoreductase-linked cytochrome) pir A59036 cytochrome c554, tetraheme, precursor - Nitrosomonas europaea - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 331.0
PYH1_k127_2807540_5 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 320.0
PYH1_k127_2807540_6 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007694 280.0
PYH1_k127_2807540_7 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000865 119.0
PYH1_k127_2807540_8 Tetratricopeptide repeat K02200 - - 0.000000000000000000000001012 106.0
PYH1_k127_2807540_9 domain protein K20276 - - 0.000008384 54.0
PYH1_k127_2815757_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 417.0
PYH1_k127_2815757_1 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000005591 123.0
PYH1_k127_2817337_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 308.0
PYH1_k127_2817337_1 Phage integrase family - - - 0.00000000000000001104 95.0
PYH1_k127_2817337_2 - - - - 0.000001109 56.0
PYH1_k127_2817350_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 5.61e-226 716.0
PYH1_k127_2817350_1 symporter activity K03307,K14387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 414.0
PYH1_k127_2817561_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 368.0
PYH1_k127_2817561_2 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
PYH1_k127_2817561_3 photosynthesis K02453,K02660 - - 0.00000000000000000000000000000000000000000000000000000001871 204.0
PYH1_k127_2827377_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K19585 - - 0.0 1508.0
PYH1_k127_2827377_1 Sigma-54 interaction domain K15836 - - 3.69e-202 651.0
PYH1_k127_2827377_10 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001754 246.0
PYH1_k127_2827377_11 protein disulfide oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 237.0
PYH1_k127_2827377_12 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000004239 218.0
PYH1_k127_2827377_13 electron transfer activity K03616 - - 0.000000000000000000000000000000000000000000000000000005906 191.0
PYH1_k127_2827377_14 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000004526 189.0
PYH1_k127_2827377_15 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000007428 169.0
PYH1_k127_2827377_16 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000000000000000000003143 152.0
PYH1_k127_2827377_17 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000004134 132.0
PYH1_k127_2827377_2 Evidence 2b Function of strongly homologous gene K18139 - - 1.035e-201 638.0
PYH1_k127_2827377_20 Methyltransferase domain - - - 0.0000000000000000001478 94.0
PYH1_k127_2827377_21 Methyltransferase domain - - - 0.00000004666 56.0
PYH1_k127_2827377_22 Ketosteroid isomerase-related protein - - - 0.000000214 55.0
PYH1_k127_2827377_23 Methyltransferase domain - - - 0.0003345 45.0
PYH1_k127_2827377_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 485.0
PYH1_k127_2827377_4 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 413.0
PYH1_k127_2827377_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 354.0
PYH1_k127_2827377_6 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 329.0
PYH1_k127_2827377_7 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001072 274.0
PYH1_k127_2827377_8 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003922 273.0
PYH1_k127_2827377_9 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001634 261.0
PYH1_k127_2828508_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.364e-218 680.0
PYH1_k127_2828508_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 466.0
PYH1_k127_2828508_10 Transposase - - - 0.000000000000000000000000000006498 127.0
PYH1_k127_2828508_11 Transposase - - - 0.0000000000000000000000001572 106.0
PYH1_k127_2828508_12 - - - - 0.000000000000000000000003326 109.0
PYH1_k127_2828508_14 Domain of unknown function (DUF5069) - - - 0.00001791 49.0
PYH1_k127_2828508_2 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002253 285.0
PYH1_k127_2828508_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001167 241.0
PYH1_k127_2828508_4 Redoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008361 225.0
PYH1_k127_2828508_5 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000004144 216.0
PYH1_k127_2828508_6 sequence-specific DNA binding K07726 - - 0.00000000000000000000000000000000000000000000001022 172.0
PYH1_k127_2828508_8 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000001979 135.0
PYH1_k127_2828508_9 endonuclease activity K03465 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.1.1.148 0.00000000000000000000000000000005607 134.0
PYH1_k127_2833500_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 459.0
PYH1_k127_2835494_0 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 570.0
PYH1_k127_2835494_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 546.0
PYH1_k127_2835494_2 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 373.0
PYH1_k127_2835494_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002538 244.0
PYH1_k127_2835494_6 Cytochrome c K03611 - - 0.0000000000007309 70.0
PYH1_k127_2853379_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 253.0
PYH1_k127_2853379_1 ATP synthase delta (OSCP) subunit K02113 - - 0.000000000000000000001319 98.0
PYH1_k127_2853379_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000122 66.0
PYH1_k127_2853471_0 amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 406.0
PYH1_k127_2853471_1 - - - - 0.000004217 51.0
PYH1_k127_2859529_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 472.0
PYH1_k127_2859529_1 Belongs to the 'phage' integrase family - - - 0.00003331 46.0
PYH1_k127_2884773_0 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 1.879e-214 672.0
PYH1_k127_2884773_1 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 446.0
PYH1_k127_2884773_2 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 423.0
PYH1_k127_2884773_3 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
PYH1_k127_2884773_4 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000006067 236.0
PYH1_k127_2884773_5 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.0000000000000000000000000000000000000000000000000001955 189.0
PYH1_k127_2888978_0 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 351.0
PYH1_k127_2888978_1 hydrolase, family 65, central catalytic - - - 0.000000000000000000000000000000000000000000000000000000000005198 211.0
PYH1_k127_2888978_2 Transposase - - - 0.0000000008034 69.0
PYH1_k127_28893_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1149.0
PYH1_k127_2891566_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 447.0
PYH1_k127_2891566_1 Domain of unknown function (DUF4258) - - - 0.0000004005 51.0
PYH1_k127_2896692_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 434.0
PYH1_k127_2896692_1 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000006647 211.0
PYH1_k127_2897446_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 391.0
PYH1_k127_2897446_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 302.0
PYH1_k127_2897446_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000002929 210.0
PYH1_k127_28979_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 473.0
PYH1_k127_28979_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
PYH1_k127_28979_2 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003096 235.0
PYH1_k127_28979_3 PFAM conserved - - - 0.0000000000000000000000000000000000000003926 156.0
PYH1_k127_2903651_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 519.0
PYH1_k127_2913409_0 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000001554 157.0
PYH1_k127_2913409_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000001598 145.0
PYH1_k127_2913409_2 - - - - 0.00000000000000000000000000000002301 126.0
PYH1_k127_2930598_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 327.0
PYH1_k127_2941156_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005906 243.0
PYH1_k127_2941156_1 - - - - 0.00000000000000001191 85.0
PYH1_k127_2941156_2 Phage integrase family - - - 0.0000000000004189 71.0
PYH1_k127_2941681_0 Tim44 K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 426.0
PYH1_k127_2941681_1 deaminated base DNA N-glycosylase activity K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 316.0
PYH1_k127_2941681_2 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 310.0
PYH1_k127_2941681_7 DNA mismatch repair enzyme - - - 0.0003295 52.0
PYH1_k127_2941681_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 GO:0000166,GO:0000959,GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032543,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070127,GO:0070149,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140053,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.0006811 46.0
PYH1_k127_2965549_0 amino acid - - - 2.691e-250 782.0
PYH1_k127_2985117_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 1.073e-295 918.0
PYH1_k127_2985117_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000002141 156.0
PYH1_k127_2985117_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000004589 139.0
PYH1_k127_2985117_3 Rubrerythrin - - - 0.000000000000000000000368 102.0
PYH1_k127_299044_0 - - - - 0.000000000000000002827 95.0
PYH1_k127_299769_0 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 450.0
PYH1_k127_299769_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000001265 166.0
PYH1_k127_299769_2 creatininase K01470 - 3.5.2.10 0.000000000000000000003763 94.0
PYH1_k127_3004913_0 Transposase DDE domain group 1 - - - 0.0000000000000000000000001057 122.0
PYH1_k127_3006642_0 mismatched DNA binding K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 398.0
PYH1_k127_3006642_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000002186 181.0
PYH1_k127_3007442_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 316.0
PYH1_k127_3008079_0 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 339.0
PYH1_k127_3008079_1 PFAM Integrase, catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
PYH1_k127_3009052_0 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 437.0
PYH1_k127_3009052_1 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 439.0
PYH1_k127_3009052_2 sulfate reduction K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 372.0
PYH1_k127_3022430_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 356.0
PYH1_k127_3036886_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 529.0
PYH1_k127_3036886_1 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000005607 106.0
PYH1_k127_3041156_0 Cupin domain - - - 0.00000000000000000000000000000000000000001991 153.0
PYH1_k127_3041156_1 BON domain - - - 0.00000000000000000000000008308 108.0
PYH1_k127_3053172_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 331.0
PYH1_k127_3053172_1 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008285 287.0
PYH1_k127_3053172_2 AMP binding - - - 0.000005206 49.0
PYH1_k127_308828_0 reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 383.0
PYH1_k127_310226_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 572.0
PYH1_k127_310226_1 DDE superfamily endonuclease K07494 - - 0.0000000000000000000000000000000000000000000000000000000000000000004242 236.0
PYH1_k127_310226_2 Transposase K07499 - - 0.00000000000000000000000000000000000000000006654 166.0
PYH1_k127_3102824_0 - K06909 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 266.0
PYH1_k127_3102824_2 tail collar domain protein - - - 0.00000000000002446 80.0
PYH1_k127_3102824_3 - - - - 0.0000000000257 69.0
PYH1_k127_3102824_4 - - - - 0.00000000002752 78.0
PYH1_k127_3102824_5 Glycosyl transferase, family 2 - - - 0.0000000003645 69.0
PYH1_k127_3102824_6 - - - - 0.00000001865 68.0
PYH1_k127_3113494_0 Transglycosylase SLT domain K08309 - - 2.766e-249 794.0
PYH1_k127_3113494_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
PYH1_k127_3113494_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000698 127.0
PYH1_k127_3115824_0 Sulfatase K01130 - 3.1.6.1 1.033e-261 811.0
PYH1_k127_3115824_1 Radical SAM superfamily K06871 - - 0.00000000000003502 72.0
PYH1_k127_3115824_2 Sodium Bile acid symporter family - - - 0.0003059 46.0
PYH1_k127_3120756_0 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 425.0
PYH1_k127_3128522_0 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 609.0
PYH1_k127_3128522_1 - - - - 0.00000000000000000000000000000001295 130.0
PYH1_k127_3133792_0 response regulator K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 498.0
PYH1_k127_3133792_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000006167 166.0
PYH1_k127_3133792_2 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.00000000000000000008862 89.0
PYH1_k127_3142603_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1267.0
PYH1_k127_3142603_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 309.0
PYH1_k127_3142603_2 Transposase K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005924 278.0
PYH1_k127_3142603_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004419 280.0
PYH1_k127_3156651_0 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 313.0
PYH1_k127_3177027_0 Transposase - - - 0.000000000001457 78.0
PYH1_k127_3177027_1 dienelactone hydrolase - - - 0.00001383 49.0
PYH1_k127_3186841_0 deoxyhypusine monooxygenase activity K02632 - 4.4.1.31 0.00000000000000000000000000000000000000000000000000000000000001121 227.0
PYH1_k127_3195843_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 443.0
PYH1_k127_3195843_1 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 400.0
PYH1_k127_3195843_13 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.000000000000006369 74.0
PYH1_k127_3195843_15 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000002233 61.0
PYH1_k127_3195843_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 375.0
PYH1_k127_3195843_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 317.0
PYH1_k127_3195843_5 Domain of unknown function (DUF5069) - - - 0.00000000000000000000000000000000000000000000000000000000000000002833 226.0
PYH1_k127_3195843_7 PilZ domain K02676 - - 0.00000000000000000000000000000000004955 140.0
PYH1_k127_3195843_8 Regulatory protein, FmdB family - - - 0.00000000000000000000000000007321 117.0
PYH1_k127_3195843_9 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.0000000000000000000000000003249 116.0
PYH1_k127_3233631_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 5.752e-221 694.0
PYH1_k127_3233631_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 539.0
PYH1_k127_3233631_2 - - - - 0.000000000000000006038 85.0
PYH1_k127_324020_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.000000000000000000000000000000009087 129.0
PYH1_k127_324020_1 transcriptional - - - 0.00000008962 62.0
PYH1_k127_324020_2 periplasmic or secreted lipoprotein K04065 - - 0.0000001217 55.0
PYH1_k127_324775_0 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 349.0
PYH1_k127_324775_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000004099 218.0
PYH1_k127_324775_4 Domain of unknown function (DUF1844) - - - 0.00000000000000004045 84.0
PYH1_k127_3261042_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000003342 76.0
PYH1_k127_3261042_1 leucine-zipper of insertion element IS481 - - - 0.000000000000009994 87.0
PYH1_k127_3304301_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 421.0
PYH1_k127_3304301_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000783 289.0
PYH1_k127_3338670_0 Formate dehydrogenase N, transmembrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 475.0
PYH1_k127_3338670_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000005167 121.0
PYH1_k127_3355660_0 AcrB/AcrD/AcrF family - - - 0.0 1812.0
PYH1_k127_3355660_1 phosphorelay signal transduction system K07714 - - 3.044e-213 669.0
PYH1_k127_3355660_10 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000000000003948 128.0
PYH1_k127_3355660_11 response regulator K03413 - - 0.0000000000000000000000000003385 121.0
PYH1_k127_3355660_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002633 106.0
PYH1_k127_3355660_13 Alginate export - - - 0.000000000000000002887 95.0
PYH1_k127_3355660_14 PFAM blue (type 1) copper domain protein - - - 0.0001331 52.0
PYH1_k127_3355660_2 Outer membrane efflux protein - - - 6.803e-196 619.0
PYH1_k127_3355660_3 photoreceptor activity K14978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 565.0
PYH1_k127_3355660_4 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 549.0
PYH1_k127_3355660_5 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 439.0
PYH1_k127_3355660_6 obsolete transcription factor activity, core RNA polymerase II binding K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 401.0
PYH1_k127_3355660_9 mRNA binding - - - 0.00000000000000000000000000000000004969 134.0
PYH1_k127_3358892_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1127.0
PYH1_k127_3358892_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 460.0
PYH1_k127_3358892_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 390.0
PYH1_k127_3358892_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 325.0
PYH1_k127_3358892_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009302 258.0
PYH1_k127_3358892_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001338 242.0
PYH1_k127_3358892_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001866 97.0
PYH1_k127_3358892_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000664 86.0
PYH1_k127_3362187_0 serine-type peptidase activity K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 312.0
PYH1_k127_3362187_1 Transmembrane region of lysyl-tRNA synthetase K07027,K14205 - 2.3.2.3 0.00000000000000000000000001566 120.0
PYH1_k127_3362400_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.45e-263 815.0
PYH1_k127_3362400_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 3.474e-229 713.0
PYH1_k127_3362400_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
PYH1_k127_3362400_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009071 249.0
PYH1_k127_3362400_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001816 245.0
PYH1_k127_3362400_5 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002655 230.0
PYH1_k127_3362400_6 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000004335 114.0
PYH1_k127_3370820_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000008879 219.0
PYH1_k127_3370820_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000797 152.0
PYH1_k127_3370820_2 Domains Cache_1, HAMP, PAS, PAS K02482 - 2.7.13.3 0.00000000000001126 85.0
PYH1_k127_3370820_3 - - - - 0.000000005324 64.0
PYH1_k127_3378909_0 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001313 251.0
PYH1_k127_3378909_1 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000228 185.0
PYH1_k127_33794_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 491.0
PYH1_k127_33794_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000009546 57.0
PYH1_k127_3383575_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 564.0
PYH1_k127_3383575_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 526.0
PYH1_k127_3383575_2 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 398.0
PYH1_k127_3383575_3 Ribosomal L32p protein family K02911 - - 0.0000000000000004873 79.0
PYH1_k127_3386746_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 299.0
PYH1_k127_3386746_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
PYH1_k127_3386746_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000003241 218.0
PYH1_k127_3386746_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000003351 201.0
PYH1_k127_3386746_4 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000001375 163.0
PYH1_k127_3386746_5 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.00000000000000000000000000000000000000000003746 164.0
PYH1_k127_3386746_6 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000000002036 102.0
PYH1_k127_3400789_0 leucine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 331.0
PYH1_k127_3407915_0 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000116 178.0
PYH1_k127_3407915_1 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000001156 132.0
PYH1_k127_3407915_2 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000002976 114.0
PYH1_k127_3407915_3 PFAM nuclease (SNase domain protein) - - - 0.000000000000000136 81.0
PYH1_k127_3407915_5 PFAM nuclease (SNase domain protein) - - - 0.0000000000000152 75.0
PYH1_k127_3413175_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 499.0
PYH1_k127_3428611_0 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 4.497e-199 629.0
PYH1_k127_3428611_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 507.0
PYH1_k127_3431209_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 559.0
PYH1_k127_3431209_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 292.0
PYH1_k127_3431209_2 23S rRNA-intervening sequence protein - - - 0.00000000889 58.0
PYH1_k127_3433198_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002264 289.0
PYH1_k127_3438568_0 Elements of external origin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 449.0
PYH1_k127_3438568_1 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000000004814 187.0
PYH1_k127_3438568_10 nucleotidyltransferase activity K07076 - - 0.00001955 52.0
PYH1_k127_3438568_2 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000000000000005179 177.0
PYH1_k127_3438568_3 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000000002677 147.0
PYH1_k127_3438568_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000001528 125.0
PYH1_k127_3438568_5 Bacterial toxin of type II toxin-antitoxin system, YafQ - - - 0.0000000000000000000000004243 106.0
PYH1_k127_3438568_6 bifunctional purine biosynthesis protein purh - - - 0.00000000000000001831 88.0
PYH1_k127_3438568_7 - - - - 0.0000001014 55.0
PYH1_k127_3438568_8 Nucleotidyltransferase domain - - - 0.0000001224 58.0
PYH1_k127_3438568_9 Transcription termination factor nusG - - - 0.0000009963 51.0
PYH1_k127_3438789_0 Heat shock 70 kDa protein K04043 - - 0.0 1120.0
PYH1_k127_3438789_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 357.0
PYH1_k127_3438789_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 341.0
PYH1_k127_3438789_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 307.0
PYH1_k127_3438789_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 303.0
PYH1_k127_3438789_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000001314 225.0
PYH1_k127_3438789_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000003839 200.0
PYH1_k127_3446900_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 323.0
PYH1_k127_3446900_1 Protein of unknown function (DUF1214) - - - 0.00000000000000000009335 91.0
PYH1_k127_3456091_0 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 419.0
PYH1_k127_3456091_1 PFAM transposase IS3 IS911 family protein K07497 - - 0.00000000000000000000000001242 111.0
PYH1_k127_3456728_0 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
PYH1_k127_3456728_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.000000000000000000000000000000000000001358 155.0
PYH1_k127_3456850_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 373.0
PYH1_k127_3465213_0 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002241 249.0
PYH1_k127_3465213_1 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000009676 158.0
PYH1_k127_3465213_10 - - - - 0.00000003916 61.0
PYH1_k127_3465213_11 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000006315 55.0
PYH1_k127_3465213_2 sugar phosphatases of the HAD superfamily K01101,K02566 - 3.1.3.41 0.000000000000000000000000000000666 126.0
PYH1_k127_3465213_3 - - - - 0.00000000000000000000000007949 116.0
PYH1_k127_3465213_4 Cell division protein FtsJ - - - 0.000000000000000002354 89.0
PYH1_k127_3465213_5 - - - - 0.000000000000001267 79.0
PYH1_k127_3465213_6 - - - - 0.0000000002259 67.0
PYH1_k127_3465213_7 DNA restriction-modification system - - - 0.0000000007689 67.0
PYH1_k127_3465213_8 - - - - 0.000000001415 61.0
PYH1_k127_3465213_9 - - - - 0.000000005018 66.0
PYH1_k127_3471878_0 Major facilitator Superfamily K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 389.0
PYH1_k127_3471878_1 CAAX protease self-immunity - - - 0.00000001613 60.0
PYH1_k127_3471878_2 - - - - 0.00000008695 57.0
PYH1_k127_3472491_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 2.107e-194 609.0
PYH1_k127_3472491_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000004035 154.0
PYH1_k127_3476191_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 587.0
PYH1_k127_3476191_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001411 268.0
PYH1_k127_3476191_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001912 240.0
PYH1_k127_3476191_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000000000000000000000000000191 170.0
PYH1_k127_3476869_0 Sigma-54 interaction domain K07714 - - 1.036e-242 754.0
PYH1_k127_3476869_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 490.0
PYH1_k127_3476869_2 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
PYH1_k127_3476869_3 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008008 256.0
PYH1_k127_3476869_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000002942 213.0
PYH1_k127_3476869_5 cellulase activity - - - 0.0000000000000000000000004265 120.0
PYH1_k127_3481832_0 photosynthesis K02453,K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 561.0
PYH1_k127_3481832_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 366.0
PYH1_k127_3481832_2 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000001493 185.0
PYH1_k127_3481832_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000006373 49.0
PYH1_k127_3481832_6 Protein of unknown function, DUF393 - - - 0.00003237 53.0
PYH1_k127_3482188_0 Beta-lactamase - - - 0.0000000000000000002448 89.0
PYH1_k127_3482188_1 - - - - 0.00000003268 66.0
PYH1_k127_3482188_2 - - - - 0.0000001096 60.0
PYH1_k127_3487298_0 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 399.0
PYH1_k127_3487298_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000003487 158.0
PYH1_k127_3495178_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 440.0
PYH1_k127_3499759_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 332.0
PYH1_k127_3499759_1 Pas domain - - - 0.00000000000000000007845 105.0
PYH1_k127_3505549_0 ABC transporter K06020 - 3.6.3.25 0.0 1036.0
PYH1_k127_3505549_1 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 355.0
PYH1_k127_3505549_2 thiolester hydrolase activity K06889,K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000029 286.0
PYH1_k127_3505549_4 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000008664 69.0
PYH1_k127_3505549_5 - - - - 0.000000000008134 70.0
PYH1_k127_3511653_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 532.0
PYH1_k127_3511653_1 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009733 243.0
PYH1_k127_3511653_2 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001114 222.0
PYH1_k127_3511653_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000916 83.0
PYH1_k127_3516810_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 445.0
PYH1_k127_3516810_1 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000000000000006255 209.0
PYH1_k127_3520316_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
PYH1_k127_3520316_1 ATP synthase delta (OSCP) subunit K02113 - - 0.00000000000000000000002184 104.0
PYH1_k127_3520316_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000009565 69.0
PYH1_k127_3527703_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000399 172.0
PYH1_k127_3527703_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000006193 77.0
PYH1_k127_3533781_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.934e-297 913.0
PYH1_k127_3533781_1 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003256 248.0
PYH1_k127_3533781_2 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
PYH1_k127_3533781_3 - - - - 0.000000000000000000000000000000000000000000001831 168.0
PYH1_k127_3533781_4 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.000000000000008832 74.0
PYH1_k127_353743_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.377e-267 846.0
PYH1_k127_353743_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 473.0
PYH1_k127_3540634_0 Cation transporter/ATPase, N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 516.0
PYH1_k127_3540634_1 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000009793 48.0
PYH1_k127_3544129_0 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000006995 205.0
PYH1_k127_3544461_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 547.0
PYH1_k127_3544461_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000001201 106.0
PYH1_k127_3545988_0 reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 432.0
PYH1_k127_3552293_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000004808 126.0
PYH1_k127_3552293_1 - - - - 0.0000000000001346 75.0
PYH1_k127_3556133_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 532.0
PYH1_k127_3556133_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 419.0
PYH1_k127_3556133_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.00000000000000000000000000000000001327 137.0
PYH1_k127_3556133_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000004887 80.0
PYH1_k127_3556133_5 Protein of unknown function (DUF433) - - - 0.0000001807 55.0
PYH1_k127_3559097_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 493.0
PYH1_k127_3561216_0 signal-transduction protein containing cAMP-binding and CBS domains K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 349.0
PYH1_k127_3561216_2 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000109 51.0
PYH1_k127_3565549_0 Belongs to the carbamoyltransferase HypF family K04656 - - 9.877e-198 635.0
PYH1_k127_3565549_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 521.0
PYH1_k127_3565549_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003289 270.0
PYH1_k127_3565549_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000008584 91.0
PYH1_k127_356808_0 peptidase dimerisation domain protein K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
PYH1_k127_356808_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000001146 104.0
PYH1_k127_3569679_1 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 450.0
PYH1_k127_3569679_2 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000001034 186.0
PYH1_k127_3571014_0 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 581.0
PYH1_k127_3571014_1 AAA domain - - - 0.0000000000000000000000000000000000000002588 152.0
PYH1_k127_3571014_2 IS66 C-terminal element - - - 0.00000000000000000000000000004739 120.0
PYH1_k127_3571014_3 Transposase DDE domain group 1 - - - 0.00000000000000000698 97.0
PYH1_k127_3571797_0 Domain of unknown function (DUF4277) - - - 0.0000000000000000000000000000000000000000003832 179.0
PYH1_k127_3587038_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 5.648e-232 726.0
PYH1_k127_3593656_0 Type II/IV secretion system protein K02454,K02652 - - 1.223e-223 706.0
PYH1_k127_3596969_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003716 226.0
PYH1_k127_3596969_1 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.0000000000000000000000000000000000000000000000000000002739 202.0
PYH1_k127_3596969_2 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000008083 112.0
PYH1_k127_3596969_4 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 0.0000000000000000000001169 98.0
PYH1_k127_3599536_0 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
PYH1_k127_3599536_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000007001 252.0
PYH1_k127_3599536_2 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
PYH1_k127_3599536_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000003275 218.0
PYH1_k127_3606020_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1071.0
PYH1_k127_3606020_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.527e-204 640.0
PYH1_k127_3606020_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 351.0
PYH1_k127_3606020_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 317.0
PYH1_k127_3606020_4 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 299.0
PYH1_k127_3613860_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 366.0
PYH1_k127_3613860_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000003712 153.0
PYH1_k127_3625796_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 3.765e-200 639.0
PYH1_k127_3625796_1 PFAM AMP-dependent synthetase and ligase - - - 2.566e-197 636.0
PYH1_k127_3625796_10 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
PYH1_k127_3625796_11 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000001824 222.0
PYH1_k127_3625796_12 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000001488 141.0
PYH1_k127_3625796_13 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000009299 102.0
PYH1_k127_3625796_14 Polysaccharide biosynthesis protein - - - 0.00000000004857 75.0
PYH1_k127_3625796_15 Phosphopantetheine attachment site K02078 - - 0.0000001206 56.0
PYH1_k127_3625796_2 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 606.0
PYH1_k127_3625796_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 511.0
PYH1_k127_3625796_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 416.0
PYH1_k127_3625796_5 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 396.0
PYH1_k127_3625796_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 326.0
PYH1_k127_3625796_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K21210 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 311.0
PYH1_k127_3625796_8 Glycosyltransferase Family 4 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 316.0
PYH1_k127_3625796_9 epimerase dehydratase K01710,K08678,K21211 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007812 284.0
PYH1_k127_362764_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 548.0
PYH1_k127_362764_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000002321 190.0
PYH1_k127_3640029_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 439.0
PYH1_k127_3640029_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000001243 197.0
PYH1_k127_3648004_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 387.0
PYH1_k127_3648004_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 382.0
PYH1_k127_3648004_2 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 319.0
PYH1_k127_366180_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000002162 73.0
PYH1_k127_3667885_0 Recombinase zinc beta ribbon domain K06400 - - 6.067e-216 685.0
PYH1_k127_3667885_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000001671 261.0
PYH1_k127_3667885_2 reverse transcriptase - - - 0.0000000000000000000000000000005324 130.0
PYH1_k127_3667885_3 Ribbon-helix-helix protein, copG family - - - 0.00000000000000001522 86.0
PYH1_k127_3668064_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 319.0
PYH1_k127_3668064_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
PYH1_k127_3668064_2 - - - - 0.0007058 43.0
PYH1_k127_3674498_0 Pup-ligase protein K20814 - 3.5.1.119 4.962e-222 693.0
PYH1_k127_3674498_1 Proteasomal ATPase OB/ID domain K13527 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 438.0
PYH1_k127_3674499_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 335.0
PYH1_k127_3674499_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 295.0
PYH1_k127_3674499_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004457 260.0
PYH1_k127_3674499_3 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001215 204.0
PYH1_k127_3674499_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000002715 183.0
PYH1_k127_3674499_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000007216 164.0
PYH1_k127_3674499_6 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000005701 93.0
PYH1_k127_3680490_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 381.0
PYH1_k127_3680490_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 364.0
PYH1_k127_3680490_2 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005056 253.0
PYH1_k127_3680490_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008225 250.0
PYH1_k127_3680490_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000004609 247.0
PYH1_k127_3692713_0 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 360.0
PYH1_k127_3692713_1 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 293.0
PYH1_k127_3692713_10 His Kinase A (phosphoacceptor) domain - - - 0.00002085 55.0
PYH1_k127_3692713_2 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 289.0
PYH1_k127_3692713_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003683 261.0
PYH1_k127_3692713_4 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000005543 207.0
PYH1_k127_3692713_5 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000295 199.0
PYH1_k127_3692713_6 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00000000000000000000000000000000000000000297 159.0
PYH1_k127_3692713_7 response regulator K02282 - - 0.0000000000000000000000000008804 118.0
PYH1_k127_3692713_9 Dienelactone hydrolase family - - - 0.00000008406 56.0
PYH1_k127_3706202_0 Cytochrome D1 heme domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 448.0
PYH1_k127_3711866_0 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 590.0
PYH1_k127_3711866_1 Evidence 2b Function of strongly homologous gene K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 460.0
PYH1_k127_3711866_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000000000001205 200.0
PYH1_k127_3711866_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source K10778 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 2.1.1.63 0.0000000000000000696 82.0
PYH1_k127_3711866_4 - - - - 0.00001808 52.0
PYH1_k127_3731313_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 463.0
PYH1_k127_3731313_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 445.0
PYH1_k127_3731313_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 299.0
PYH1_k127_3731313_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
PYH1_k127_375105_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 292.0
PYH1_k127_375105_3 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000002911 106.0
PYH1_k127_376289_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 576.0
PYH1_k127_376289_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
PYH1_k127_376289_2 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 433.0
PYH1_k127_376289_3 AcrB/AcrD/AcrF family K15726 - - 0.0005809 42.0
PYH1_k127_376363_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.846e-244 782.0
PYH1_k127_376363_1 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000001227 235.0
PYH1_k127_376363_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000012 150.0
PYH1_k127_377022_0 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 360.0
PYH1_k127_377022_1 negative regulation of translational initiation K05554,K14670,K15886 - 2.3.1.235 0.0000000000000000000000000000000000000000000000000007982 190.0
PYH1_k127_377390_0 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000007217 177.0
PYH1_k127_377390_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000003358 129.0
PYH1_k127_377390_2 transporter component K07112 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000004296 83.0
PYH1_k127_3777568_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 1.235e-217 681.0
PYH1_k127_3777568_1 pyruvate decarboxylase activity K04103 - 4.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 553.0
PYH1_k127_3777568_2 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000001365 248.0
PYH1_k127_3800758_0 phosphoserine phosphatase activity K02668,K07710,K07711,K10942 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 576.0
PYH1_k127_3800758_1 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit B K10945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 527.0
PYH1_k127_3800758_10 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.0000001389 53.0
PYH1_k127_3800758_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 476.0
PYH1_k127_3800758_3 Carboxysome Shell Carbonic Anhydrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 460.0
PYH1_k127_3800758_4 Ammonia monooxygenase K10944 - 1.14.18.3,1.14.99.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
PYH1_k127_3800758_5 Sulfate permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003687 254.0
PYH1_k127_3800758_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000199 158.0
PYH1_k127_3800758_7 transposase and inactivated derivatives, IS30 family - - - 0.000000000000000000000000000000001961 134.0
PYH1_k127_3800758_8 phosphorelay signal transduction system - - - 0.00000000000000000000007265 103.0
PYH1_k127_3800758_9 transposase and inactivated derivatives, IS30 family - - - 0.0000000000001949 75.0
PYH1_k127_380514_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 562.0
PYH1_k127_380514_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 396.0
PYH1_k127_380514_2 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.0000000000000000000000000000000000000000000008852 168.0
PYH1_k127_380514_3 Domain of unknown function (DUF5069) - - - 0.0000000000000000005943 91.0
PYH1_k127_380514_4 - - - - 0.0000000001598 64.0
PYH1_k127_3821603_1 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000006215 229.0
PYH1_k127_3823098_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001644 280.0
PYH1_k127_3823098_1 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000000000000001325 141.0
PYH1_k127_3829160_0 Protein of unknown function (DUF1566) - - - 0.00000000000000004095 89.0
PYH1_k127_3829160_1 PFAM Bacterial Ig-like domain (group 2) - - - 0.00000000000000009155 89.0
PYH1_k127_3829160_2 - - - - 0.00000000000001035 87.0
PYH1_k127_3841066_0 Sulfatase K01130 - 3.1.6.1 6.532e-206 643.0
PYH1_k127_3842599_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1445.0
PYH1_k127_3842599_1 Elongator protein 3, MiaB family, Radical SAM - - - 4.54e-316 972.0
PYH1_k127_3842599_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 412.0
PYH1_k127_3852653_0 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 516.0
PYH1_k127_3852653_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 434.0
PYH1_k127_3852653_2 - K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000004099 233.0
PYH1_k127_3852653_5 pectinesterase activity - - - 0.000000000000000000000000000001794 123.0
PYH1_k127_3852653_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000008966 114.0
PYH1_k127_3852653_7 - - - - 0.000000000000000000000002975 112.0
PYH1_k127_3856749_0 MacB-like periplasmic core domain K02004 - - 4.034e-209 655.0
PYH1_k127_3856749_1 Evidence 2b Function of strongly homologous gene K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000003711 234.0
PYH1_k127_3859918_0 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000001158 99.0
PYH1_k127_3859918_1 - - - - 0.00004963 54.0
PYH1_k127_3863327_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1365.0
PYH1_k127_3863327_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1305.0
PYH1_k127_3863327_2 FAD binding domain K00239 - 1.3.5.1,1.3.5.4 2.107e-318 977.0
PYH1_k127_3863327_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.468e-225 702.0
PYH1_k127_3863327_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 460.0
PYH1_k127_3886_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 398.0
PYH1_k127_3886_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 351.0
PYH1_k127_3886_2 PFAM Integrase catalytic - - - 0.00001681 50.0
PYH1_k127_3889349_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.07e-312 969.0
PYH1_k127_3889349_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.984e-253 786.0
PYH1_k127_3889349_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 585.0
PYH1_k127_3889349_3 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 342.0
PYH1_k127_3889349_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 283.0
PYH1_k127_3889349_5 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000002994 208.0
PYH1_k127_3889349_6 LysM domain - - - 0.0000000000000000000000000000000000000000000006556 174.0
PYH1_k127_3889349_7 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000001029 132.0
PYH1_k127_3902008_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 3.036e-246 766.0
PYH1_k127_3902008_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000009945 192.0
PYH1_k127_3904548_0 Recombinase - - - 1.622e-314 978.0
PYH1_k127_3904548_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 439.0
PYH1_k127_3914458_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 446.0
PYH1_k127_3914458_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 427.0
PYH1_k127_3914458_2 High confidence in function and specificity - - - 0.00004626 46.0
PYH1_k127_3917666_0 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 542.0
PYH1_k127_3917666_1 Protein of unknown function (DUF1156) K07445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 420.0
PYH1_k127_3917666_2 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007501 256.0
PYH1_k127_3917666_3 Putative DNA-binding domain K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000007778 182.0
PYH1_k127_3926046_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 399.0
PYH1_k127_3926046_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 342.0
PYH1_k127_3926046_2 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 287.0
PYH1_k127_3934119_0 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 310.0
PYH1_k127_3934119_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001885 245.0
PYH1_k127_3934119_2 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000009484 151.0
PYH1_k127_3949925_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 456.0
PYH1_k127_3949925_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 306.0
PYH1_k127_3949925_2 PD-(D/E)XK nuclease superfamily - - - 0.0006704 50.0
PYH1_k127_3964378_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000006974 167.0
PYH1_k127_3964378_1 Resolvase domain - - - 0.0000000000000000000000007518 105.0
PYH1_k127_3964378_2 Family of unknown function (DUF5372) - - - 0.000008758 48.0
PYH1_k127_3973904_0 oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
PYH1_k127_3973904_1 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000001506 244.0
PYH1_k127_3973904_2 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000001179 165.0
PYH1_k127_3973904_3 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0000001632 53.0
PYH1_k127_397548_0 Domain of unknown function (DUF4406) - - - 0.0000000000000001583 84.0
PYH1_k127_3991750_0 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 449.0
PYH1_k127_3991750_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000009497 147.0
PYH1_k127_4024529_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000008149 192.0
PYH1_k127_4024529_2 Sulfurtransferase TusA - - - 0.000000000000000000000000000004812 121.0
PYH1_k127_4024529_3 Helix-turn-helix domain - - - 0.00004802 47.0
PYH1_k127_4037031_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 469.0
PYH1_k127_4037031_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 394.0
PYH1_k127_4037031_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH1_k127_4037031_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
PYH1_k127_4041607_0 coenzyme binding K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 394.0
PYH1_k127_4041607_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000006504 158.0
PYH1_k127_4041607_2 - - - - 0.0000000000000000000000000000000004786 135.0
PYH1_k127_4054237_0 Integrase, catalytic region - - - 3.016e-202 634.0
PYH1_k127_4056819_0 transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 378.0
PYH1_k127_4057054_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 384.0
PYH1_k127_4057054_1 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001294 248.0
PYH1_k127_4057054_10 - - - - 0.0008684 44.0
PYH1_k127_4057054_4 - - - - 0.000000000000000000000006605 102.0
PYH1_k127_4057054_7 - - - - 0.000000000003169 68.0
PYH1_k127_4057054_9 - - - - 0.000002733 55.0
PYH1_k127_406097_0 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000008073 173.0
PYH1_k127_406097_1 domain, Protein - - - 0.000000000003369 68.0
PYH1_k127_4124866_0 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.0 2197.0
PYH1_k127_4124866_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 5.936e-301 921.0
PYH1_k127_4124866_2 Transglutaminase/protease-like homologues - - - 2.718e-200 646.0
PYH1_k127_4124866_3 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 339.0
PYH1_k127_4124866_6 - - - - 0.0001283 47.0
PYH1_k127_4126379_0 Cytochrome D1 heme domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 410.0
PYH1_k127_41304_0 acyl-CoA dehydrogenase - - - 6.573e-264 823.0
PYH1_k127_4135487_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 544.0
PYH1_k127_4135487_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 432.0
PYH1_k127_4135487_3 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000001782 84.0
PYH1_k127_417978_0 spermidine synthase activity K00797 - 2.5.1.16 5.168e-219 688.0
PYH1_k127_417978_1 branched-chain-amino-acid transaminase activity K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 334.0
PYH1_k127_417978_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001594 238.0
PYH1_k127_417978_4 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000874 196.0
PYH1_k127_417978_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000000000000000000000000001112 176.0
PYH1_k127_4188536_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 443.0
PYH1_k127_4188536_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000004343 104.0
PYH1_k127_4204862_0 4Fe-4S dicluster domain K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 401.0
PYH1_k127_4204862_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 322.0
PYH1_k127_4204862_2 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000001219 168.0
PYH1_k127_4208301_0 Protein involved in outer membrane biogenesis K07290 - - 1.098e-218 688.0
PYH1_k127_4208301_1 Metallopeptidase family M24 K01262 - 3.4.11.9 5.522e-194 611.0
PYH1_k127_4208301_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001154 262.0
PYH1_k127_4212865_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 361.0
PYH1_k127_4212865_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000004055 190.0
PYH1_k127_4212865_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000005712 86.0
PYH1_k127_4215498_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 489.0
PYH1_k127_4215498_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 338.0
PYH1_k127_4215717_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1620.0
PYH1_k127_4215717_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 4.469e-217 682.0
PYH1_k127_4215717_2 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 543.0
PYH1_k127_4215717_3 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 437.0
PYH1_k127_4215717_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH1_k127_4216454_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.745e-207 650.0
PYH1_k127_4216454_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001105 248.0
PYH1_k127_4216454_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000005005 195.0
PYH1_k127_4216454_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000006528 144.0
PYH1_k127_4216454_4 - - - - 0.00000000000000000000000000000000005491 143.0
PYH1_k127_4216454_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000005367 107.0
PYH1_k127_4216454_6 RNA recognition motif - - - 0.000000004419 62.0
PYH1_k127_4216454_7 GAF domain - - - 0.00004127 47.0
PYH1_k127_4217135_0 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 469.0
PYH1_k127_4227364_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 463.0
PYH1_k127_4227364_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 396.0
PYH1_k127_4227364_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000001012 56.0
PYH1_k127_4228191_0 Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 516.0
PYH1_k127_4228191_1 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.0000000000000000000000001487 109.0
PYH1_k127_4230541_0 Transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 481.0
PYH1_k127_4236609_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 412.0
PYH1_k127_4236609_1 Integrase core domain protein - - - 0.000000000000000000000000000000000000000000000001384 187.0
PYH1_k127_4236609_2 - - - - 0.00000000000000000000005047 103.0
PYH1_k127_4236609_3 Peptidase family M28 - - - 0.00009168 54.0
PYH1_k127_4238848_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 409.0
PYH1_k127_4244613_0 Protein of unknown function (DUF1214) - - - 2.955e-223 694.0
PYH1_k127_4246121_1 the current gene model (or a revised gene model) may contain a premature stop - - - 0.000000000000000000000000000000000001318 139.0
PYH1_k127_4246121_2 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000001001 114.0
PYH1_k127_4250645_0 IMG reference gene - - - 0.0000000000000000000000000000000000004825 151.0
PYH1_k127_4250645_1 Transposase - - - 0.00000000000000000000000000004488 117.0
PYH1_k127_4250645_2 - - - - 0.00000001416 65.0
PYH1_k127_4251136_0 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
PYH1_k127_4265248_0 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001939 242.0
PYH1_k127_4267037_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 559.0
PYH1_k127_4267037_1 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 501.0
PYH1_k127_4267037_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 335.0
PYH1_k127_4267037_3 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000000000000000000000000000396 175.0
PYH1_k127_4267037_7 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000001406 57.0
PYH1_k127_4273976_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 350.0
PYH1_k127_4273976_1 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000001336 179.0
PYH1_k127_4274325_0 Resolvase domain - - - 1.945e-268 841.0
PYH1_k127_4276438_0 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000004277 218.0
PYH1_k127_4276438_1 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000001822 131.0
PYH1_k127_4282579_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 8.279e-234 731.0
PYH1_k127_4293243_0 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 606.0
PYH1_k127_4297608_0 Carbamoyltransferase K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 380.0
PYH1_k127_4297608_1 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 335.0
PYH1_k127_4297608_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001664 259.0
PYH1_k127_4297608_3 Helix-turn-helix domain K07497 - - 0.0000000000000000000000000000000005728 132.0
PYH1_k127_4297608_4 Transposase K07483 - - 0.000000000000000000000000000006175 123.0
PYH1_k127_4297608_5 COG2801 Transposase and inactivated derivatives K00986,K07497 - 2.7.7.49 0.000000000000000001062 94.0
PYH1_k127_4297608_6 Belongs to the 'phage' integrase family - - - 0.0000000000000003571 81.0
PYH1_k127_4297608_7 ABC transporter K01996 - - 0.00000001392 55.0
PYH1_k127_4297608_8 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000004384 54.0
PYH1_k127_4297608_9 PFAM Major Facilitator Superfamily - - - 0.000005323 51.0
PYH1_k127_4298090_0 PFAM Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005516 248.0
PYH1_k127_4298090_1 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000213 139.0
PYH1_k127_4307181_0 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.0000000000000000000000000000000008783 130.0
PYH1_k127_4307181_1 coenzyme binding K07071 - - 0.0000000000000000000000000008767 115.0
PYH1_k127_4308256_0 PFAM Integrase, catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 451.0
PYH1_k127_4308256_1 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 372.0
PYH1_k127_4308256_2 AAA domain - - - 0.00000000003777 68.0
PYH1_k127_4308256_3 DDE superfamily endonuclease - - - 0.0001643 45.0
PYH1_k127_4311291_0 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 361.0
PYH1_k127_4311291_2 IS66 Orf2 like protein - - - 0.0003196 46.0
PYH1_k127_43187_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 589.0
PYH1_k127_43187_1 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 497.0
PYH1_k127_43187_2 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 463.0
PYH1_k127_43187_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 363.0
PYH1_k127_43187_7 - - - - 0.000002935 51.0
PYH1_k127_4328393_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 420.0
PYH1_k127_4328393_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000004976 106.0
PYH1_k127_4328393_2 transmembrane transport - - - 0.000000003417 59.0
PYH1_k127_4336452_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006082 282.0
PYH1_k127_4338246_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 325.0
PYH1_k127_4338246_1 30S ribosomal protein S14 K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000008613 115.0
PYH1_k127_4338246_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000001794 66.0
PYH1_k127_4339963_0 PFAM Response regulator receiver domain K11624 - - 0.00000000000000000000000000000000000000000000000000000000000000003209 230.0
PYH1_k127_4339963_1 Histidine kinase-like ATPases - - - 0.00000001557 57.0
PYH1_k127_4340048_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1202.0
PYH1_k127_4340048_1 HlyD membrane-fusion protein of T1SS K03585 - - 0.0000000000000000000000001425 108.0
PYH1_k127_4345433_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 347.0
PYH1_k127_4345433_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000003456 127.0
PYH1_k127_4345723_0 PFAM integrase - - - 0.0000000000000000000000000000000000000003095 164.0
PYH1_k127_4366387_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
PYH1_k127_4366387_1 PAS domain K07652 - 2.7.13.3 0.000000000000000000002643 96.0
PYH1_k127_4392364_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 332.0
PYH1_k127_4392364_1 FecCD transport family K02015 - - 0.000000000504 67.0
PYH1_k127_4396696_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 394.0
PYH1_k127_4396696_1 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001809 254.0
PYH1_k127_4396696_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006617 229.0
PYH1_k127_4396696_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000001232 165.0
PYH1_k127_4396696_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000001655 164.0
PYH1_k127_4396696_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000002592 160.0
PYH1_k127_4396696_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004346 130.0
PYH1_k127_4396696_7 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001106 76.0
PYH1_k127_4396737_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 469.0
PYH1_k127_4396737_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 393.0
PYH1_k127_4396737_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000002073 161.0
PYH1_k127_4396737_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000008776 132.0
PYH1_k127_4396737_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000003668 119.0
PYH1_k127_4396737_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003412 77.0
PYH1_k127_4396737_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 341.0
PYH1_k127_4396737_3 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 289.0
PYH1_k127_4396737_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007017 256.0
PYH1_k127_4396737_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004681 229.0
PYH1_k127_4396737_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000009377 186.0
PYH1_k127_4396737_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000001256 186.0
PYH1_k127_4396737_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000009347 161.0
PYH1_k127_4396737_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000189 161.0
PYH1_k127_4401773_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.392e-238 747.0
PYH1_k127_4405460_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 509.0
PYH1_k127_4405460_1 Psort location Extracellular, score K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 299.0
PYH1_k127_4405460_10 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000007486 74.0
PYH1_k127_4405460_12 beta-lactamase activity K07126 - - 0.0001385 46.0
PYH1_k127_4405460_2 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000009813 180.0
PYH1_k127_4405460_3 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000319 186.0
PYH1_k127_4405460_6 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000004486 104.0
PYH1_k127_4405460_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000005804 93.0
PYH1_k127_4405460_8 - - - - 0.000000000000000007995 88.0
PYH1_k127_4405460_9 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000006896 78.0
PYH1_k127_4411324_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 8.5e-227 707.0
PYH1_k127_4411324_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 524.0
PYH1_k127_4411324_2 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
PYH1_k127_4412908_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 589.0
PYH1_k127_4412908_1 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000002632 181.0
PYH1_k127_4412908_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.0000000000000000000001331 99.0
PYH1_k127_4429856_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1433.0
PYH1_k127_4429856_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 355.0
PYH1_k127_4429856_2 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004489 249.0
PYH1_k127_4429856_3 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000001193 116.0
PYH1_k127_4430867_0 iron dependent repressor - - - 1.044e-194 623.0
PYH1_k127_4430867_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000003578 138.0
PYH1_k127_4436936_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 529.0
PYH1_k127_4436936_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 339.0
PYH1_k127_4436936_2 DDE superfamily endonuclease - - - 0.0004132 43.0
PYH1_k127_4444657_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 313.0
PYH1_k127_4444657_1 enoyl-CoA hydratase - - - 0.00000000000000000000008991 99.0
PYH1_k127_4445186_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000177 223.0
PYH1_k127_4445186_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000001434 123.0
PYH1_k127_4460395_0 - - - - 0.0000000000000000000000000000000007982 133.0
PYH1_k127_4460395_1 - - - - 0.000000000000000000001417 95.0
PYH1_k127_4460395_2 - - - - 0.00000000000000000007383 90.0
PYH1_k127_4460395_3 - - - - 0.0000000000000001641 83.0
PYH1_k127_4460395_4 - - - - 0.000000000000007841 75.0
PYH1_k127_4460395_5 ORF located using Blastx - - - 0.00000000000176 69.0
PYH1_k127_4460395_6 - - - - 0.00000000002645 63.0
PYH1_k127_4460395_7 ORF located using Blastx - - - 0.00001781 51.0
PYH1_k127_4460826_0 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 597.0
PYH1_k127_4460826_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
PYH1_k127_4469280_0 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 327.0
PYH1_k127_4471386_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000000002911 228.0
PYH1_k127_4471386_1 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000003099 216.0
PYH1_k127_4471386_2 Bacterial antitoxin of type II TA system, VapB - - - 0.00000001408 56.0
PYH1_k127_4477531_0 PFAM Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 321.0
PYH1_k127_4477531_1 Tetratricopeptide repeat - - - 0.00004291 52.0
PYH1_k127_4477531_2 IMG reference gene - - - 0.00009243 46.0
PYH1_k127_4481571_0 Transposase K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 308.0
PYH1_k127_4481571_1 Transposase K07497 - - 0.0000000000000000000001601 100.0
PYH1_k127_4481571_2 CoA binding domain K06929 - - 0.00000000000000000002618 91.0
PYH1_k127_4494507_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001038 295.0
PYH1_k127_4494507_1 Type II and III secretion system protein K02453 - - 0.00000000000000005975 92.0
PYH1_k127_4497290_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1177.0
PYH1_k127_4497290_1 Cytochrome c K00405 - - 9.553e-211 662.0
PYH1_k127_4497290_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 422.0
PYH1_k127_4497290_3 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 412.0
PYH1_k127_4497290_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000009786 210.0
PYH1_k127_4497290_6 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000000000003173 165.0
PYH1_k127_4507646_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 485.0
PYH1_k127_4507646_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.0000000000000000000000000000000000000000000000000000001682 195.0
PYH1_k127_4507646_2 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000000004562 178.0
PYH1_k127_4507646_3 YCII-related domain K09780 - - 0.00000000000000002345 85.0
PYH1_k127_4507646_4 Tetratricopeptide repeat - - - 0.0000001202 64.0
PYH1_k127_4519153_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007081 254.0
PYH1_k127_4519153_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000005283 190.0
PYH1_k127_4521989_0 Glycogen debranching enzyme - - - 7.381e-291 895.0
PYH1_k127_4521989_1 Glycogen debranching enzyme - - - 2.597e-244 762.0
PYH1_k127_4521989_2 alpha amylase, catalytic region - - - 0.0000000001991 64.0
PYH1_k127_4531890_0 Cytochrome c K12263 - - 2.443e-257 797.0
PYH1_k127_4531890_1 polyphosphate kinase activity K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 560.0
PYH1_k127_4531890_10 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000000000000000006165 184.0
PYH1_k127_4531890_11 IMP dehydrogenase activity K09137 - - 0.00000000000000000000000000000000000000002287 157.0
PYH1_k127_4531890_12 diguanylate cyclase - - - 0.0000000000000000000000000000000000000003964 153.0
PYH1_k127_4531890_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000003874 123.0
PYH1_k127_4531890_14 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000009234 99.0
PYH1_k127_4531890_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000008515 75.0
PYH1_k127_4531890_16 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000001135 64.0
PYH1_k127_4531890_17 DnaK suppressor protein - - - 0.0000000001861 66.0
PYH1_k127_4531890_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 550.0
PYH1_k127_4531890_3 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 377.0
PYH1_k127_4531890_4 Cytochrome c K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
PYH1_k127_4531890_5 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000105 226.0
PYH1_k127_4531890_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000009347 228.0
PYH1_k127_4531890_7 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000000000000008472 215.0
PYH1_k127_4531890_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000004546 195.0
PYH1_k127_4547382_0 Psort location CytoplasmicMembrane, score K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 582.0
PYH1_k127_4547382_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000001099 149.0
PYH1_k127_4547382_2 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000003586 64.0
PYH1_k127_4550070_0 Amidohydrolase family - - - 0.0000000000000625 81.0
PYH1_k127_4555197_0 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 547.0
PYH1_k127_4555197_1 - - - - 0.000000000000000001779 87.0
PYH1_k127_459958_0 COG3335 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000006107 199.0
PYH1_k127_459958_1 Helix-turn-helix domain - - - 0.00000000000000000000000001663 113.0
PYH1_k127_4604384_0 Conserved carboxylase domain K01960 - 6.4.1.1 0.0 1020.0
PYH1_k127_4604384_1 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000002651 170.0
PYH1_k127_4604384_2 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00001507 49.0
PYH1_k127_462842_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 415.0
PYH1_k127_4634889_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 510.0
PYH1_k127_4634889_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 474.0
PYH1_k127_4634889_2 LmbE family - - - 0.0000000000000000000000000000000000000000000000002384 181.0
PYH1_k127_4634889_4 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000001125 115.0
PYH1_k127_4636311_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0 1112.0
PYH1_k127_4636311_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
PYH1_k127_4636311_2 Associated with various cellular activities K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 468.0
PYH1_k127_4636311_3 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000008786 250.0
PYH1_k127_4636311_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002736 230.0
PYH1_k127_4636311_5 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000006182 162.0
PYH1_k127_4636311_7 Pfam:DUF989 - - - 0.000000000000000000000000000000006807 128.0
PYH1_k127_4636311_8 DUF167 K09131 - - 0.0000000000000000000000000309 114.0
PYH1_k127_4636311_9 - - - - 0.00000878 56.0
PYH1_k127_4638765_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1067.0
PYH1_k127_4638765_1 serine-type endopeptidase activity K08372 - - 0.000000000000000000000000000000000000000000000000000000000006839 221.0
PYH1_k127_4638765_2 response regulator K02667 - - 0.0000000000000002168 84.0
PYH1_k127_4651243_0 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 323.0
PYH1_k127_4651243_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000003535 140.0
PYH1_k127_466131_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 6.16e-213 670.0
PYH1_k127_466131_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 349.0
PYH1_k127_4663412_0 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 274.0
PYH1_k127_4663412_1 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000000000000000001139 207.0
PYH1_k127_4663412_2 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000002164 97.0
PYH1_k127_4667202_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 287.0
PYH1_k127_4667202_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000005237 68.0
PYH1_k127_4669863_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 1.334e-196 618.0
PYH1_k127_4669863_1 Belongs to the sirtuin family. Class K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 364.0
PYH1_k127_4669863_2 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 330.0
PYH1_k127_4670627_0 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 495.0
PYH1_k127_4670627_1 Animal haem peroxidase - - - 0.0000000000000000000213 94.0
PYH1_k127_46790_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.758e-317 983.0
PYH1_k127_46790_1 Rieske (2fe-2S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 449.0
PYH1_k127_46790_3 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000004611 168.0
PYH1_k127_46790_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000006302 121.0
PYH1_k127_468412_0 HTH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 404.0
PYH1_k127_468412_1 Belongs to the 'phage' integrase family K14059 - - 0.0001078 46.0
PYH1_k127_469672_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000001202 144.0
PYH1_k127_4706422_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 406.0
PYH1_k127_4706422_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 344.0
PYH1_k127_4706422_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 309.0
PYH1_k127_4706422_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 293.0
PYH1_k127_4706422_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004242 255.0
PYH1_k127_4712579_0 Belongs to the citrate synthase family K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.0 1148.0
PYH1_k127_4712579_1 ATP citrate lyase citrate-binding K15231 - 2.3.3.8 0.00000000000000000000000000000000000000407 145.0
PYH1_k127_4712579_2 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000000000000000000003066 102.0
PYH1_k127_4725437_0 COG5659 FOG Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000081 289.0
PYH1_k127_4725437_4 His Kinase A (phosphoacceptor) domain - - - 0.000008385 50.0
PYH1_k127_4748686_0 - - - - 0.0000000000000000000000000000000001144 135.0
PYH1_k127_4748686_1 - - - - 0.000000000000000000000000001916 113.0
PYH1_k127_4748686_2 - - - - 0.000000000000000000000001988 106.0
PYH1_k127_4748686_3 - - - - 0.000000000001609 71.0
PYH1_k127_4748686_4 - - - - 0.000000000002844 67.0
PYH1_k127_4755052_0 Evidence 2b Function of strongly homologous gene K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 529.0
PYH1_k127_4755052_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
PYH1_k127_4766659_0 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 593.0
PYH1_k127_4766659_1 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 401.0
PYH1_k127_4766659_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 291.0
PYH1_k127_4798663_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 519.0
PYH1_k127_4798663_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000003099 169.0
PYH1_k127_4802775_0 Fic/DOC family K04095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
PYH1_k127_4802775_1 Transposase DDE domain - - - 0.0000000000001116 70.0
PYH1_k127_4802775_2 - - - - 0.0006157 42.0
PYH1_k127_480588_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1337.0
PYH1_k127_480588_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1114.0
PYH1_k127_480588_10 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000006807 263.0
PYH1_k127_480588_11 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
PYH1_k127_480588_12 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.00000000000000000000000000000000000000000000000000000006034 211.0
PYH1_k127_480588_2 Surface antigen - - - 6.474e-197 620.0
PYH1_k127_480588_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 555.0
PYH1_k127_480588_4 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 416.0
PYH1_k127_480588_5 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 393.0
PYH1_k127_480588_6 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 393.0
PYH1_k127_480588_7 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 368.0
PYH1_k127_480588_8 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 364.0
PYH1_k127_480588_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005972 272.0
PYH1_k127_4812909_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000002153 181.0
PYH1_k127_4812909_1 PD-(D/E)XK nuclease superfamily - - - 0.0000003215 55.0
PYH1_k127_4815774_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 304.0
PYH1_k127_4815774_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000005343 176.0
PYH1_k127_4815774_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000006098 102.0
PYH1_k127_48229_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 534.0
PYH1_k127_48229_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 333.0
PYH1_k127_4842514_0 oxidoreductase activity K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 304.0
PYH1_k127_4842514_1 transferase activity, transferring acyl groups - - - 0.000000000000000000000000002349 117.0
PYH1_k127_4842514_2 Transglycosylase SLT domain - - - 0.00000000000000000000004349 98.0
PYH1_k127_4850644_0 metallopeptidase activity K01993,K13408,K16922 - - 1.585e-204 656.0
PYH1_k127_4850644_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 425.0
PYH1_k127_4868627_0 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 509.0
PYH1_k127_4868627_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 443.0
PYH1_k127_4868627_2 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 297.0
PYH1_k127_4868627_3 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000001994 197.0
PYH1_k127_4868627_4 MarC family integral membrane protein K05595 - - 0.0003852 45.0
PYH1_k127_4869833_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 551.0
PYH1_k127_4869946_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 587.0
PYH1_k127_4869946_3 - - - - 0.0002427 46.0
PYH1_k127_4875167_1 RNA recognition motif - - - 0.0000000000000000000000000000000000000000003752 161.0
PYH1_k127_4875167_2 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000004082 99.0
PYH1_k127_4877299_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 5.089e-223 702.0
PYH1_k127_4877299_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 366.0
PYH1_k127_4877299_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000001024 247.0
PYH1_k127_4877299_4 ATPase or kinase K06925 - - 0.0000000000000000000000000007679 122.0
PYH1_k127_488559_0 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000004701 160.0
PYH1_k127_488559_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000001275 162.0
PYH1_k127_4889362_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 561.0
PYH1_k127_4889362_1 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 370.0
PYH1_k127_4889362_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 347.0
PYH1_k127_4889362_3 Protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000000000000000000000000000000001467 240.0
PYH1_k127_4889362_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000001638 236.0
PYH1_k127_4889362_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001264 206.0
PYH1_k127_4889362_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002911 201.0
PYH1_k127_4889362_7 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000001653 169.0
PYH1_k127_4889362_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005954 71.0
PYH1_k127_4889503_0 ABC transporter K06158 - - 1.11e-268 832.0
PYH1_k127_4889503_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000001838 64.0
PYH1_k127_4903566_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1313.0
PYH1_k127_4903566_1 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 480.0
PYH1_k127_4914603_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000004859 100.0
PYH1_k127_4914603_1 Protein tyrosine kinase - - - 0.0003952 53.0
PYH1_k127_4914603_2 Trypsin-like peptidase domain - - - 0.0005222 52.0
PYH1_k127_4919499_0 phosphorelay signal transduction system K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000001166 160.0
PYH1_k127_4919499_1 - - - - 0.000000000000000001399 92.0
PYH1_k127_4919499_2 Glycine-zipper domain - - - 0.000000000003702 66.0
PYH1_k127_4934469_0 - - - - 0.00000000000000000000000000000000000000000000002358 178.0
PYH1_k127_4943795_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000533 66.0
PYH1_k127_4945616_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 6.564e-242 752.0
PYH1_k127_4945616_1 Histidyl-tRNA synthetase K02502 - - 0.000000000005044 69.0
PYH1_k127_4947209_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 331.0
PYH1_k127_4947209_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000007273 159.0
PYH1_k127_4949723_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 548.0
PYH1_k127_4949723_1 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000007276 199.0
PYH1_k127_496105_0 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 1.769e-240 753.0
PYH1_k127_496105_1 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 638.0
PYH1_k127_496105_2 Alpha/beta hydrolase family K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 340.0
PYH1_k127_496105_3 Uncharacterized conserved protein (DUF2294) - - - 0.00000000000000000000000000000000000761 137.0
PYH1_k127_5023791_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 608.0
PYH1_k127_5023791_1 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000001729 150.0
PYH1_k127_5023791_2 protein conserved in cyanobacteria - - - 0.0000879 45.0
PYH1_k127_5045131_0 Animal haem peroxidase - - - 0.0 1402.0
PYH1_k127_5045131_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 464.0
PYH1_k127_5045131_2 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006523 276.0
PYH1_k127_5045131_3 PIN domain - - - 0.000000000000000000000000001779 117.0
PYH1_k127_5045131_4 toxin-antitoxin pair type II binding - - - 0.00000000000000000000007774 99.0
PYH1_k127_5045131_5 hmm pf02371 K07486 - - 0.00000000002602 65.0
PYH1_k127_5045271_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 574.0
PYH1_k127_5045271_1 - - - - 0.00000000000000000000000000000000833 134.0
PYH1_k127_5045582_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 6.054e-249 769.0
PYH1_k127_504603_0 arylsulfatase A K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 437.0
PYH1_k127_5049134_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 319.0
PYH1_k127_5049134_1 - - - - 0.0000197 50.0
PYH1_k127_5050900_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 425.0
PYH1_k127_5053614_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000004463 224.0
PYH1_k127_5055066_0 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 507.0
PYH1_k127_5055066_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 441.0
PYH1_k127_5055066_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 432.0
PYH1_k127_5055066_3 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000001318 163.0
PYH1_k127_5055066_4 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000003744 138.0
PYH1_k127_5056188_0 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000002412 194.0
PYH1_k127_5060951_0 Phosphoglycerate kinase K00927 - 2.7.2.3 6.402e-220 687.0
PYH1_k127_5060951_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.107e-201 642.0
PYH1_k127_5060951_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 583.0
PYH1_k127_5060951_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 289.0
PYH1_k127_5060951_4 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000000633 144.0
PYH1_k127_5065759_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 3.13e-230 719.0
PYH1_k127_5065759_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 8.829e-216 676.0
PYH1_k127_5065759_10 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000002579 205.0
PYH1_k127_5065759_11 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000001773 211.0
PYH1_k127_5065759_12 PIN domain - - - 0.000000000000000000000000000000000000000000008111 166.0
PYH1_k127_5065759_13 response to nickel cation K07723 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000004852 97.0
PYH1_k127_5065759_15 Regulator of microtubule dynamics protein 1 - - - 0.000000004675 66.0
PYH1_k127_5065759_2 Protein export membrane protein K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 499.0
PYH1_k127_5065759_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 471.0
PYH1_k127_5065759_4 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 398.0
PYH1_k127_5065759_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 330.0
PYH1_k127_5065759_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 332.0
PYH1_k127_5065759_7 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007287 277.0
PYH1_k127_5065759_8 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000248 261.0
PYH1_k127_5065759_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.00000000000000000000000000000000000000000000000000000000008519 213.0
PYH1_k127_5072515_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 282.0
PYH1_k127_5072952_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000007231 278.0
PYH1_k127_5072952_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000006295 256.0
PYH1_k127_5072952_11 Belongs to the helicase family. UvrD subfamily K07465 - - 0.0000000000000000000000005248 114.0
PYH1_k127_5072952_13 Belongs to the ParB family K03497 - - 0.0000000000000000000000179 114.0
PYH1_k127_5072952_14 acetyltransferase - - - 0.000000000000000000002091 109.0
PYH1_k127_5072952_15 Putative metallopeptidase domain - - - 0.0000000000000002069 93.0
PYH1_k127_5072952_16 associated with various cellular activities - - - 0.00000000000009687 84.0
PYH1_k127_5072952_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000001169 81.0
PYH1_k127_5072952_18 DNA ligase D, 3-phosphoesterase domain - - - 0.0000000000006741 82.0
PYH1_k127_5072952_19 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000003798 77.0
PYH1_k127_5072952_23 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000901 60.0
PYH1_k127_5072952_24 n-acetylmuramoyl-L-alanine amidase - - - 0.0001328 54.0
PYH1_k127_5072952_3 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000004671 195.0
PYH1_k127_5072952_5 snf2 family - - - 0.000000000000000000000000000000000000000000008903 183.0
PYH1_k127_5072952_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000001352 176.0
PYH1_k127_5072952_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000005494 167.0
PYH1_k127_5072952_9 Pkd domain containing protein - - - 0.0000000000000000000000000000007824 135.0
PYH1_k127_5078878_0 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 577.0
PYH1_k127_5079550_0 PFAM Mammalian cell entry related domain protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 561.0
PYH1_k127_5079550_1 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008803 262.0
PYH1_k127_5079550_2 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000000000000000000000002032 157.0
PYH1_k127_5079550_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000003881 134.0
PYH1_k127_5079550_4 PFAM Paraquat-inducible protein A K03808 - - 0.0000000000000000009777 87.0
PYH1_k127_5080067_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 606.0
PYH1_k127_5085071_0 PFAM Copper resistance D K07245 - - 2.47e-294 916.0
PYH1_k127_5085071_1 transposition, DNA-mediated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 353.0
PYH1_k127_5085071_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 247.0
PYH1_k127_5085071_3 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000000000000000000000000000000000000000000000000000007638 225.0
PYH1_k127_5085071_4 - - - - 0.000000000000000000000000000000000000000000000000000000005267 205.0
PYH1_k127_5085071_5 - - - - 0.0000000000000000000000000000000000000000000000000002383 191.0
PYH1_k127_5085071_6 PFAM Copper resistance protein CopC K07156 - - 0.00000000000000000000000000000000000000000000000002034 183.0
PYH1_k127_5092264_0 metallocarboxypeptidase activity K01299,K03281 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 521.0
PYH1_k127_509788_0 Sulfatase - - - 2.669e-239 753.0
PYH1_k127_509788_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 308.0
PYH1_k127_509788_2 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000001547 162.0
PYH1_k127_509788_3 PIN domain - - - 0.00000000000000000000000000000002111 130.0
PYH1_k127_509788_4 SpoVT / AbrB like domain - - - 0.0000000000000859 74.0
PYH1_k127_5101130_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004155 292.0
PYH1_k127_5101130_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001172 256.0
PYH1_k127_5101130_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000008113 194.0
PYH1_k127_5101130_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000001636 79.0
PYH1_k127_5101130_4 PFAM SMP-30 Gluconolaconase K08685,K14274 GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 1.4.9.1 0.00000003319 61.0
PYH1_k127_5102120_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 483.0
PYH1_k127_5102120_1 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 435.0
PYH1_k127_5102120_10 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
PYH1_k127_5102120_11 - - - - 0.00000000000000000000000000000000001426 143.0
PYH1_k127_5102120_12 - - - - 0.0000000000000000000000000000000003306 136.0
PYH1_k127_5102120_14 Phage integrase SAM-like domain - - - 0.00000000000000000000000001442 111.0
PYH1_k127_5102120_16 Replication initiation factor K07467 - - 0.000000000000000000002918 98.0
PYH1_k127_5102120_17 PFAM nuclease (SNase domain protein) - - - 0.0000000000000008636 81.0
PYH1_k127_5102120_18 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000001556 74.0
PYH1_k127_5102120_19 Sel1-like repeats. - - - 0.00000002137 56.0
PYH1_k127_5102120_2 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 435.0
PYH1_k127_5102120_21 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000209 51.0
PYH1_k127_5102120_22 Staphylococcal nuclease homologues K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.00003331 46.0
PYH1_k127_5102120_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 427.0
PYH1_k127_5102120_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 417.0
PYH1_k127_5102120_5 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 377.0
PYH1_k127_5102120_6 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 331.0
PYH1_k127_5102120_7 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 318.0
PYH1_k127_5102120_8 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 308.0
PYH1_k127_5102120_9 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000006693 214.0
PYH1_k127_5110212_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 415.0
PYH1_k127_511074_0 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 521.0
PYH1_k127_5111763_0 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000001257 141.0
PYH1_k127_5111763_1 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.0000001043 56.0
PYH1_k127_5112852_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 2.678e-235 737.0
PYH1_k127_5112852_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.54e-210 664.0
PYH1_k127_5112852_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 453.0
PYH1_k127_5112852_3 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 323.0
PYH1_k127_5112852_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 319.0
PYH1_k127_5112852_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000004283 262.0
PYH1_k127_5112852_6 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000004332 227.0
PYH1_k127_5112852_7 acetyltransferase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
PYH1_k127_5112852_8 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.000000000000000000000000000000000001855 139.0
PYH1_k127_5112852_9 phosphorelay sensor kinase activity K16923 - - 0.0000001464 64.0
PYH1_k127_5113196_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 546.0
PYH1_k127_5113196_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 383.0
PYH1_k127_5113196_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 345.0
PYH1_k127_5113196_3 - - - - 0.000000000000000000000000000000000000000001082 161.0
PYH1_k127_5113196_4 - - - - 0.000000000000000000000000000000000000006426 152.0
PYH1_k127_5113196_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000002618 78.0
PYH1_k127_5124086_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 375.0
PYH1_k127_5124086_1 Preprotein translocase SecG subunit K03075 - - 0.00001795 48.0
PYH1_k127_5140177_0 Proteasome subunit K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000001279 247.0
PYH1_k127_5140177_1 Pup-ligase protein K20814 - 3.5.1.119 0.000000000000000000000000000000000000000000000000000000000000000000000008689 244.0
PYH1_k127_5140177_2 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.000000000000000000000002342 107.0
PYH1_k127_5141652_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1440.0
PYH1_k127_5144913_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 457.0
PYH1_k127_5144913_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 469.0
PYH1_k127_5144913_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 334.0
PYH1_k127_5144913_3 tRNA 3'-trailer cleavage - - - 0.00000000000000302 76.0
PYH1_k127_5149986_0 response regulator, receiver - - - 0.00000000004734 63.0
PYH1_k127_5149986_1 PFAM transcription factor CarD K07736 - - 0.000005201 55.0
PYH1_k127_5150531_0 Sulfatase K01130 - 3.1.6.1 3.799e-251 782.0
PYH1_k127_5150998_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
PYH1_k127_5150998_1 similarity to OMNI NTL01RS2573 K07485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 339.0
PYH1_k127_5150998_2 heme binding K00463 - 1.13.11.52 0.00000000000000000001472 93.0
PYH1_k127_5156503_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.011e-199 623.0
PYH1_k127_5156503_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 598.0
PYH1_k127_5156503_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 544.0
PYH1_k127_5156503_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 465.0
PYH1_k127_5156503_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 458.0
PYH1_k127_5156503_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 387.0
PYH1_k127_5169667_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 384.0
PYH1_k127_5169667_1 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.0000000000000000000000000000000000000001373 157.0
PYH1_k127_5171966_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.395e-243 768.0
PYH1_k127_5171966_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000003785 212.0
PYH1_k127_5176132_0 Aminotransferase class I and II K10206 - 2.6.1.83 3.039e-211 659.0
PYH1_k127_5176132_1 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000000000000001105 79.0
PYH1_k127_5176993_0 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 377.0
PYH1_k127_5177861_0 ATPase activity - - - 1.391e-277 859.0
PYH1_k127_5177861_1 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 387.0
PYH1_k127_5177861_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 361.0
PYH1_k127_5177861_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 269.0
PYH1_k127_5177861_5 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.000000000000000000000000000000000000000000000000005922 185.0
PYH1_k127_5177861_7 Cytochrome c - - - 0.00000000000000000000000000000000104 145.0
PYH1_k127_5177861_8 cysteine-type peptidase activity - - - 0.000000000000000000005942 97.0
PYH1_k127_5180726_0 COG3385 FOG Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 485.0
PYH1_k127_5180726_1 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 383.0
PYH1_k127_5180726_2 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000001964 151.0
PYH1_k127_5183220_0 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 445.0
PYH1_k127_5183220_1 transcription factor binding K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 452.0
PYH1_k127_5183220_2 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002626 243.0
PYH1_k127_5183220_3 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000001679 174.0
PYH1_k127_5198904_0 - - - - 0.0000000000000000000000000000000002115 134.0
PYH1_k127_5198904_1 - - - - 0.00000000000000000007219 89.0
PYH1_k127_5198904_2 - - - - 0.00000000000000718 76.0
PYH1_k127_5205206_0 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 569.0
PYH1_k127_5205206_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 559.0
PYH1_k127_5205206_2 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
PYH1_k127_5205206_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000005887 195.0
PYH1_k127_5205206_4 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000002306 104.0
PYH1_k127_5205206_5 Protein of unknown function (DUF1207) - - - 0.0000001181 54.0
PYH1_k127_5216570_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 552.0
PYH1_k127_5216570_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006323 279.0
PYH1_k127_5216570_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000393 58.0
PYH1_k127_5218990_0 helicase activity K03579 - 3.6.4.13 0.0 1097.0
PYH1_k127_5218990_1 helicase activity K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004609 252.0
PYH1_k127_5223895_0 bacterial-type flagellum-dependent cell motility - - - 0.0000009416 62.0
PYH1_k127_5245981_0 - - - - 0.000000000000000000000000000000002619 130.0
PYH1_k127_5245981_1 - - - - 0.0000000000000000000000000009858 114.0
PYH1_k127_5245981_10 - - - - 0.00000000104 65.0
PYH1_k127_5245981_2 - - - - 0.00000000000000000000000001377 111.0
PYH1_k127_5245981_3 - - - - 0.000000000000000006258 85.0
PYH1_k127_5245981_6 - - - - 0.0000000000000008044 78.0
PYH1_k127_5245981_7 - - - - 0.000000000000846 68.0
PYH1_k127_5251214_0 Uncharacterised protein family (UPF0160) - - - 0.000000000000000000000000000000000000000000000000004435 192.0
PYH1_k127_5251214_1 mitochondrial electron transport, NADH to ubiquinone K10353 - 2.7.1.76 0.00000000000000000000000000000008822 132.0
PYH1_k127_5251214_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000001122 134.0
PYH1_k127_5251214_3 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000171 101.0
PYH1_k127_5254336_0 belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 5.691e-231 726.0
PYH1_k127_5254336_1 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 358.0
PYH1_k127_5254336_2 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 355.0
PYH1_k127_5254336_3 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 305.0
PYH1_k127_5254336_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000002428 226.0
PYH1_k127_5254336_5 CHAD - - - 0.0000000000000000000000000000000000000000000000000000005288 211.0
PYH1_k127_5257182_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 7.512e-237 738.0
PYH1_k127_5257182_1 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 547.0
PYH1_k127_5257182_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 437.0
PYH1_k127_526482_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 443.0
PYH1_k127_526482_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000002702 84.0
PYH1_k127_5275957_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 282.0
PYH1_k127_5293106_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 334.0
PYH1_k127_5293106_1 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 252.0
PYH1_k127_5294063_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 514.0
PYH1_k127_5294063_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000004628 185.0
PYH1_k127_5311154_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 522.0
PYH1_k127_5311154_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000001224 68.0
PYH1_k127_5314660_0 Glycogen debranching enzyme - - - 3.098e-269 832.0
PYH1_k127_5314660_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 378.0
PYH1_k127_5314660_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 349.0
PYH1_k127_5331594_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 511.0
PYH1_k127_5331594_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 404.0
PYH1_k127_5331594_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
PYH1_k127_5331594_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000886 139.0
PYH1_k127_5331594_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000006282 71.0
PYH1_k127_5336852_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1091.0
PYH1_k127_5336852_1 Participates in both transcription termination and antitermination K02600 - - 5.193e-207 649.0
PYH1_k127_5336852_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000001143 192.0
PYH1_k127_5336852_3 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000000001392 137.0
PYH1_k127_5337787_0 ATPase activity K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 505.0
PYH1_k127_5337787_1 bacteriocin transport K03561,K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000002479 139.0
PYH1_k127_5337787_2 thiamine transport K02011 - - 0.000000000000000000000000000000000006546 136.0
PYH1_k127_5340262_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.758e-310 959.0
PYH1_k127_5340262_1 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 488.0
PYH1_k127_5340262_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000007847 133.0
PYH1_k127_5345260_0 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001505 259.0
PYH1_k127_5345260_1 Transposase - - - 0.000005493 53.0
PYH1_k127_5349990_0 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 378.0
PYH1_k127_5349990_1 xylulokinase activity K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 307.0
PYH1_k127_5357984_0 Protein of unknown function, DUF255 K06888 - - 3.427e-200 646.0
PYH1_k127_5357984_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001542 222.0
PYH1_k127_5357984_2 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000000000000000000000000004568 156.0
PYH1_k127_5359795_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000003405 183.0
PYH1_k127_5359795_1 transporter component K07112 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000003963 57.0
PYH1_k127_5365530_0 High confidence in function and specificity - - - 0.000000000000000000000000000000004333 135.0
PYH1_k127_5365530_1 transposition K07497 - - 0.0000000000000000000000000000002218 124.0
PYH1_k127_5365530_2 Transposase - - - 0.00000000000000000000000187 108.0
PYH1_k127_5371243_0 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 484.0
PYH1_k127_5381040_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 504.0
PYH1_k127_5381040_1 Amidohydrolase family K01443,K02564 - 3.5.1.25,3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 439.0
PYH1_k127_5381040_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 304.0
PYH1_k127_5387324_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000007761 144.0
PYH1_k127_5387324_1 amino acid - - - 0.00000000000000000000000000000289 124.0
PYH1_k127_5393611_0 Major facilitator Superfamily K08218 - - 2.603e-250 781.0
PYH1_k127_5399385_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 499.0
PYH1_k127_5399385_1 Protein of unknown function (DUF4238) - - - 0.00000000000000000000000000000000000000000000000000000000001535 210.0
PYH1_k127_5399385_2 transposase activity K07483,K07497 - - 0.000000000000000000000000000000000000000000000000001336 187.0
PYH1_k127_5401817_0 AcrB/AcrD/AcrF family - - - 2.762e-292 903.0
PYH1_k127_5403773_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 331.0
PYH1_k127_5403773_1 transposase gene. There are two copies of the ISChy3 element in this genome - - - 0.000000000000000000000000000000000000000000000000000000003503 212.0
PYH1_k127_5403773_2 Transposase K07494 - - 0.0000000000000000000000005451 111.0
PYH1_k127_5403773_3 Transposase - - - 0.000000000000006073 84.0
PYH1_k127_5403773_4 Winged helix-turn helix - - - 0.000006658 50.0
PYH1_k127_5404153_0 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 274.0
PYH1_k127_5404153_1 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000000000000000009087 172.0
PYH1_k127_5404153_2 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000006646 147.0
PYH1_k127_5404153_3 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000001881 62.0
PYH1_k127_5417839_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
PYH1_k127_5417839_1 PFAM TrkA-C domain protein K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 407.0
PYH1_k127_5417839_2 Glutathione S-transferase, N-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000007719 162.0
PYH1_k127_542035_0 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 337.0
PYH1_k127_5431826_0 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 413.0
PYH1_k127_5431826_1 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000005287 59.0
PYH1_k127_5437164_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 578.0
PYH1_k127_5437164_1 Domain of unknown function (DUF1330) - - - 0.00000000000000000000009177 97.0
PYH1_k127_5454061_0 FAD binding domain K00278 - 1.4.3.16 4.06e-253 788.0
PYH1_k127_5454061_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 430.0
PYH1_k127_5454061_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 408.0
PYH1_k127_5454061_3 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 382.0
PYH1_k127_5454061_4 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002752 265.0
PYH1_k127_5454061_5 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000000000000000006302 121.0
PYH1_k127_5465802_0 transposase - - - 0.00000000000000000000000000000000000000000000000000000000000001895 236.0
PYH1_k127_5465802_1 KTSC domain - - - 0.000000859 55.0
PYH1_k127_5465802_2 - - - - 0.000006764 51.0
PYH1_k127_5470291_0 efflux transmembrane transporter activity K03287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 476.0
PYH1_k127_5470291_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004468 272.0
PYH1_k127_5477052_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 4.149e-227 711.0
PYH1_k127_5477052_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 1.829e-210 665.0
PYH1_k127_5477052_2 tRNA processing K06864,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 354.0
PYH1_k127_5477052_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001262 262.0
PYH1_k127_5477052_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
PYH1_k127_5477052_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000002796 138.0
PYH1_k127_5477052_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000009058 70.0
PYH1_k127_5514123_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 6.861e-207 655.0
PYH1_k127_5514123_1 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001543 288.0
PYH1_k127_5515070_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 580.0
PYH1_k127_5515070_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 573.0
PYH1_k127_5515070_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 351.0
PYH1_k127_5521187_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 382.0
PYH1_k127_5521187_1 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000001244 196.0
PYH1_k127_5521811_0 Putative glucoamylase K13688 - - 0.0 1384.0
PYH1_k127_5521811_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1304.0
PYH1_k127_5521811_2 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0 1022.0
PYH1_k127_5521811_3 - - - - 0.000000000000000000000000000000000000001261 151.0
PYH1_k127_5523644_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000001101 271.0
PYH1_k127_5528700_0 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000006256 185.0
PYH1_k127_5528700_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000001438 138.0
PYH1_k127_5528700_2 PFAM transposase, IS4 family protein - - - 0.000000000000000000004329 96.0
PYH1_k127_5528700_3 PFAM transposase, IS4 family protein - - - 0.00000000000006308 79.0
PYH1_k127_5535986_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002544 259.0
PYH1_k127_5540888_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 350.0
PYH1_k127_5544204_0 TonB-dependent receptor - - - 0.0 1014.0
PYH1_k127_5544204_1 response to nickel cation K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000002267 211.0
PYH1_k127_5544204_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000001596 127.0
PYH1_k127_5545430_0 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 325.0
PYH1_k127_5545430_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 298.0
PYH1_k127_5545430_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000001277 171.0
PYH1_k127_5545430_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000001834 170.0
PYH1_k127_5545430_4 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000116 106.0
PYH1_k127_5559807_0 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 438.0
PYH1_k127_5559807_1 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005784 241.0
PYH1_k127_5559807_2 DNA integration - - - 0.0000000000000000000000000000000000000000000000000000000000002042 217.0
PYH1_k127_5559807_3 Cro/C1-type HTH DNA-binding domain - - - 0.00001448 49.0
PYH1_k127_5568993_0 Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 483.0
PYH1_k127_5568993_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 318.0
PYH1_k127_5568993_2 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000001727 214.0
PYH1_k127_5568993_3 Transposase - - - 0.00000000003861 64.0
PYH1_k127_5575031_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1241.0
PYH1_k127_5575031_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000004523 233.0
PYH1_k127_5575031_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004581 219.0
PYH1_k127_5575031_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000001429 197.0
PYH1_k127_5575031_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000003467 78.0
PYH1_k127_55805_0 BEST Arabidopsis thaliana protein match is Plant protein of - - - 0.00000000000000000000000000000000002418 156.0
PYH1_k127_55805_1 Fibronectin type 3 domain - - - 0.000000000000000000000000000000006293 149.0
PYH1_k127_5601509_0 Sulfatase K01130,K01138 - 3.1.6.1 0.0 1175.0
PYH1_k127_5601509_1 PFAM Filamentation induced by cAMP death on curing-related K07341 - - 0.0000000000000000000000000000004601 126.0
PYH1_k127_5601509_2 sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000002039 115.0
PYH1_k127_5601509_3 PFAM SpoVT AbrB K07172,K18842 - - 0.00000000000007158 74.0
PYH1_k127_5611623_0 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000002354 224.0
PYH1_k127_5611623_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000001394 97.0
PYH1_k127_5611623_2 - - - - 0.00001336 48.0
PYH1_k127_5615545_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 3.209e-228 712.0
PYH1_k127_5615545_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.594e-200 629.0
PYH1_k127_5615545_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 496.0
PYH1_k127_5615545_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 413.0
PYH1_k127_5615545_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
PYH1_k127_5615545_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
PYH1_k127_5615545_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000004933 250.0
PYH1_k127_5615545_7 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000005006 130.0
PYH1_k127_5631357_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.904e-286 886.0
PYH1_k127_5631357_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000438 222.0
PYH1_k127_5631357_2 bacterial (prokaryotic) histone like domain K04764 - - 0.00000000000000000000000000000000000000000000008727 169.0
PYH1_k127_5650779_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.097e-240 745.0
PYH1_k127_5650779_1 Pfam:DUF989 - - - 0.00000000000000000000000000000000000000000000000000000000000001894 215.0
PYH1_k127_5658663_0 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 309.0
PYH1_k127_5658663_1 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
PYH1_k127_5675625_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.075e-236 739.0
PYH1_k127_5690422_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 518.0
PYH1_k127_5690422_1 Amidohydrolase K07045 - - 0.0007219 46.0
PYH1_k127_5701784_0 asparaginase activity K01424,K05597 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1,3.5.1.38 0.00000000000000000000000000000000000000000000000000000000001663 211.0
PYH1_k127_5701784_1 PFAM glycoside hydrolase, family 13 domain protein - - - 0.0000000000000000000162 95.0
PYH1_k127_5704137_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 2.983e-257 803.0
PYH1_k127_5710329_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 342.0
PYH1_k127_5710329_1 Acetyl-CoA hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
PYH1_k127_5732379_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 332.0
PYH1_k127_5751525_0 transcription factor binding K02584,K12146,K15836 - - 2.993e-278 874.0
PYH1_k127_5751525_1 efflux transmembrane transporter activity K02004 - - 1.186e-208 655.0
PYH1_k127_5751525_2 actin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 514.0
PYH1_k127_5751525_4 Evidence 2b Function of strongly homologous gene K02003,K09810,K09814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 372.0
PYH1_k127_5751525_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 307.0
PYH1_k127_575947_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.252e-292 900.0
PYH1_k127_5769891_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1158.0
PYH1_k127_5769891_1 methylisocitrate lyase activity K01841,K07281 - 2.7.7.74,5.4.2.9 2.622e-310 956.0
PYH1_k127_5769891_2 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 563.0
PYH1_k127_5769891_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 289.0
PYH1_k127_5769891_4 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
PYH1_k127_5769891_5 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003736 256.0
PYH1_k127_5769891_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001143 203.0
PYH1_k127_5769891_7 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000004057 180.0
PYH1_k127_5775000_0 Fatty acid cis/trans isomerase (CTI) - - - 0.0 1168.0
PYH1_k127_5775000_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000906 193.0
PYH1_k127_5777996_0 exonuclease activity K16899 - 3.6.4.12 4.918e-258 831.0
PYH1_k127_5777996_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 473.0
PYH1_k127_578648_0 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 313.0
PYH1_k127_578648_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K21449 - - 0.0000000000000000000001112 108.0
PYH1_k127_5791193_0 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 329.0
PYH1_k127_5791193_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000001776 251.0
PYH1_k127_5791193_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000007405 99.0
PYH1_k127_5793566_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 526.0
PYH1_k127_5793566_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 465.0
PYH1_k127_5793566_3 - - - - 0.0000000000000000000000000000000000000003964 153.0
PYH1_k127_5793566_4 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000002826 122.0
PYH1_k127_5794262_0 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000602 184.0
PYH1_k127_5794262_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000302 167.0
PYH1_k127_5795978_0 sulfuric ester hydrolase activity K01002,K01138 - 2.7.8.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 529.0
PYH1_k127_5795978_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000001343 192.0
PYH1_k127_5795978_2 regulation of translation K03530 - - 0.000000000000000000000000000000000000001497 151.0
PYH1_k127_5795978_4 PFAM nuclease (SNase domain protein) - - - 0.000000000724 63.0
PYH1_k127_5795978_5 nuclease K01174 - 3.1.31.1 0.00000005125 57.0
PYH1_k127_5795978_6 deoxyribonuclease I activity K01150 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 0.0000002439 53.0
PYH1_k127_5795978_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00009782 53.0
PYH1_k127_5851335_0 PFAM transposase IS4 family protein - - - 1.4e-253 792.0
PYH1_k127_5851335_1 Transposase DDE domain group 1 - - - 0.000000000000000000000000006363 112.0
PYH1_k127_5851335_2 PFAM response regulator receiver - - - 0.000000000000000000001051 96.0
PYH1_k127_5861948_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 523.0
PYH1_k127_5861948_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00001094 48.0
PYH1_k127_5867755_0 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 538.0
PYH1_k127_5867755_2 - - - - 0.0000000000000000000000000000005313 122.0
PYH1_k127_586793_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 436.0
PYH1_k127_5882321_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 437.0
PYH1_k127_5882321_1 malic protein domain protein K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000006342 231.0
PYH1_k127_5882321_2 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000000000004446 102.0
PYH1_k127_588337_0 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 449.0
PYH1_k127_588337_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000002625 168.0
PYH1_k127_5884601_0 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 528.0
PYH1_k127_5884601_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000001276 193.0
PYH1_k127_5884601_2 Alkyl sulfatase dimerisation K01138 - - 0.0000000009289 61.0
PYH1_k127_5886954_0 Belongs to the citrate synthase family K01647,K01659 GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 518.0
PYH1_k127_5886954_1 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 348.0
PYH1_k127_5886954_2 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000006395 177.0
PYH1_k127_5886954_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000002474 171.0
PYH1_k127_5886954_4 Transposase - - - 0.000000000000000000000000000000006323 130.0
PYH1_k127_5886954_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000001198 75.0
PYH1_k127_5886954_6 PFAM nuclease (SNase domain protein) - - - 0.00000000000007929 75.0
PYH1_k127_5886954_7 - - - - 0.000000387 56.0
PYH1_k127_5888230_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.308e-254 785.0
PYH1_k127_5888230_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.156e-211 661.0
PYH1_k127_5888230_2 ATPase activity K02013,K02028,K05776 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 345.0
PYH1_k127_5888230_3 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 287.0
PYH1_k127_5888230_4 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000001879 187.0
PYH1_k127_5888230_5 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000002374 61.0
PYH1_k127_5890104_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000415 279.0
PYH1_k127_5890104_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
PYH1_k127_5890104_2 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000005421 210.0
PYH1_k127_5890104_3 energy transducer activity K03646,K03832 - - 0.000000000000000000000000000000000000000000000000009581 195.0
PYH1_k127_5895280_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 4.376e-249 780.0
PYH1_k127_5895280_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 565.0
PYH1_k127_5895280_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 519.0
PYH1_k127_5895280_3 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 507.0
PYH1_k127_5895280_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 351.0
PYH1_k127_5895280_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
PYH1_k127_5895280_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 324.0
PYH1_k127_5895280_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003134 280.0
PYH1_k127_5897033_0 TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000008674 222.0
PYH1_k127_5897033_1 hmm pf01609 - - - 0.000000000000000000000000000000000000000000000001273 191.0
PYH1_k127_5902309_0 Aldehyde dehydrogenase family - - - 3.749e-218 685.0
PYH1_k127_5902309_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 3.133e-196 617.0
PYH1_k127_5902309_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 553.0
PYH1_k127_5902309_3 arginine decarboxylase activity K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 351.0
PYH1_k127_5902309_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 295.0
PYH1_k127_5906239_0 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000009136 185.0
PYH1_k127_5906239_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.000000000000000000000000000000000000000158 175.0
PYH1_k127_5911029_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 344.0
PYH1_k127_5911029_1 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
PYH1_k127_5911029_2 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000001182 232.0
PYH1_k127_5911029_3 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000001239 179.0
PYH1_k127_5911029_4 THUMP - - - 0.0001125 48.0
PYH1_k127_5911484_0 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 418.0
PYH1_k127_5911484_1 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 390.0
PYH1_k127_5911484_2 PEP-CTERM motif - - - 0.000006058 51.0
PYH1_k127_5915624_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006462 263.0
PYH1_k127_5915624_1 Domain of unknown function (DUF3332) - - - 0.00000000000000000003213 98.0
PYH1_k127_5917615_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000000000452 206.0
PYH1_k127_5917615_1 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.000000000000000000000000000000000000000000000000001093 190.0
PYH1_k127_5917615_3 hydroperoxide reductase activity - - - 0.000000000000000000000000000002317 136.0
PYH1_k127_5917615_4 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0002677 44.0
PYH1_k127_5920814_0 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 297.0
PYH1_k127_5920814_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001521 279.0
PYH1_k127_5920814_2 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000000000164 138.0
PYH1_k127_5920814_3 MraZ protein, putative antitoxin-like K03925 - - 0.000000000006638 69.0
PYH1_k127_5920814_4 Excisionase - - - 0.00000000009229 64.0
PYH1_k127_5924763_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 3.467e-212 664.0
PYH1_k127_5924763_1 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 458.0
PYH1_k127_5924763_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 422.0
PYH1_k127_5924763_3 PFAM TrkA-C domain protein K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 405.0
PYH1_k127_5924763_4 lipid binding K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 296.0
PYH1_k127_5924763_6 Glutathione S-transferase, N-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000003911 162.0
PYH1_k127_5924763_8 Protein of unknown function DUF72 - - - 0.0002075 48.0
PYH1_k127_5926738_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.934e-260 808.0
PYH1_k127_5926738_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.134e-251 782.0
PYH1_k127_5926738_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 331.0
PYH1_k127_5926738_3 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000783 264.0
PYH1_k127_5926738_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000009801 161.0
PYH1_k127_5926909_0 (ABC) transporter K15738 - - 3.272e-249 776.0
PYH1_k127_5926909_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 457.0
PYH1_k127_5926935_0 Transposase DDE domain - - - 2.287e-198 635.0
PYH1_k127_5928249_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 488.0
PYH1_k127_5928249_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 350.0
PYH1_k127_5928249_2 homoserine kinase activity K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004994 269.0
PYH1_k127_5928249_3 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000001009 232.0
PYH1_k127_5928249_4 FMN reductase (NADPH) activity - - - 0.000000000000000000000000000000000000000000000008603 181.0
PYH1_k127_5928249_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000006143 100.0
PYH1_k127_5928249_6 - - - - 0.0000000000000000002463 94.0
PYH1_k127_5928249_7 Transposase and inactivated derivatives K00986,K07497 - 2.7.7.49 0.000000000006145 67.0
PYH1_k127_5931135_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 585.0
PYH1_k127_5933552_0 Glutathione S-transferase K00799,K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7,2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 411.0
PYH1_k127_5933552_1 - - - - 0.000000000000000000000000001419 113.0
PYH1_k127_5940026_0 Sodium/calcium exchanger protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 496.0
PYH1_k127_5940026_1 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000001263 151.0
PYH1_k127_5940026_2 Ion channel - - - 0.00000000000391 67.0
PYH1_k127_5950071_0 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 387.0
PYH1_k127_5950071_1 smart pdz dhr glgf K04771 - 3.4.21.107 0.000001248 57.0
PYH1_k127_5950127_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000004259 229.0
PYH1_k127_5950127_1 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000001942 187.0
PYH1_k127_5950127_3 - - - - 0.0002158 54.0
PYH1_k127_5950127_4 - - - - 0.0005538 52.0
PYH1_k127_5951894_0 Transcriptional regulator - - - 0.0000000000000000000000000000001009 130.0
PYH1_k127_5951894_2 SMART Rhodanese domain protein - - - 0.0009645 43.0
PYH1_k127_5952655_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 557.0
PYH1_k127_5952655_1 - - - - 0.00000000000000000000000000000000000000000000000000000000344 199.0
PYH1_k127_5952655_10 - - - - 0.00000000000002401 73.0
PYH1_k127_5952655_11 Peptidase M56 - - - 0.0000000000004189 82.0
PYH1_k127_5952655_12 - - - - 0.0000000000006027 71.0
PYH1_k127_5952655_13 - - - - 0.000000000001025 70.0
PYH1_k127_5952655_14 - - - - 0.000000000004207 72.0
PYH1_k127_5952655_15 COG NOG15344 non supervised orthologous group - - - 0.000000000004275 70.0
PYH1_k127_5952655_16 - - - - 0.00000000006239 63.0
PYH1_k127_5952655_17 non supervised orthologous group - - - 0.0000000003386 60.0
PYH1_k127_5952655_18 - - - - 0.0000000006061 59.0
PYH1_k127_5952655_19 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.00000006543 57.0
PYH1_k127_5952655_2 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000004041 176.0
PYH1_k127_5952655_23 - - - - 0.0001025 49.0
PYH1_k127_5952655_3 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000000000000000000141 148.0
PYH1_k127_5952655_4 - - - - 0.00000000000000000000000000004869 119.0
PYH1_k127_5952655_5 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000344 102.0
PYH1_k127_5952655_6 - - - - 0.00000000000000000006547 90.0
PYH1_k127_5952655_7 - - - - 0.000000000000000003103 85.0
PYH1_k127_5952655_8 - - - - 0.0000000000000001079 83.0
PYH1_k127_5952655_9 - - - - 0.00000000000000077 77.0
PYH1_k127_5959215_0 - K01992 - - 2.523e-232 733.0
PYH1_k127_5959215_1 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 325.0
PYH1_k127_5962994_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.647e-267 827.0
PYH1_k127_5965759_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1320.0
PYH1_k127_5965759_1 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 594.0
PYH1_k127_5965759_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 398.0
PYH1_k127_5965759_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
PYH1_k127_5965759_5 DNA integration - - - 0.000000000006323 73.0
PYH1_k127_5965759_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0004005 46.0
PYH1_k127_5967840_0 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 316.0
PYH1_k127_5967840_1 Integrase core domain - - - 0.000000001897 60.0
PYH1_k127_5973029_0 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 591.0
PYH1_k127_5973029_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 468.0
PYH1_k127_5973029_2 FIST C domain - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 448.0
PYH1_k127_5973029_3 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001428 189.0
PYH1_k127_5978692_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 8.293e-259 817.0
PYH1_k127_5987255_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 2.43e-248 770.0
PYH1_k127_5987255_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001656 221.0
PYH1_k127_5992164_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1121.0
PYH1_k127_5992164_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 392.0
PYH1_k127_5992164_2 Domain of unknown function (DUF4321) - - - 0.000000000000000000000000000000004346 130.0
PYH1_k127_5996647_0 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 361.0
PYH1_k127_5996647_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000001564 202.0
PYH1_k127_59997_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000001867 181.0
PYH1_k127_6002472_0 Transposase IS4 family - - - 6.87e-205 647.0
PYH1_k127_6007598_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 9.25e-319 984.0
PYH1_k127_6007598_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 8.446e-219 691.0
PYH1_k127_6007598_2 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000003962 175.0
PYH1_k127_6008562_0 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 465.0
PYH1_k127_6008562_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000004393 157.0
PYH1_k127_6008562_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000000006032 139.0
PYH1_k127_6008562_3 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000002204 142.0
PYH1_k127_6008562_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000008291 110.0
PYH1_k127_6008562_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000001827 102.0
PYH1_k127_6012891_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.2e-209 667.0
PYH1_k127_6021636_0 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 382.0
PYH1_k127_6021636_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000001438 243.0
PYH1_k127_6036193_0 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 5.42e-197 616.0
PYH1_k127_6036193_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K00387 - 1.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 560.0
PYH1_k127_6036193_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 429.0
PYH1_k127_6036193_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000001236 99.0
PYH1_k127_6037172_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 417.0
PYH1_k127_6037172_1 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 357.0
PYH1_k127_6037172_2 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 332.0
PYH1_k127_6037172_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000168 288.0
PYH1_k127_6037172_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 285.0
PYH1_k127_6037172_5 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000001594 204.0
PYH1_k127_6037172_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003226 191.0
PYH1_k127_6037172_7 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000002409 172.0
PYH1_k127_6037172_8 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000000000000000000000003543 169.0
PYH1_k127_6037172_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000003817 159.0
PYH1_k127_6038604_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 569.0
PYH1_k127_6038604_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 365.0
PYH1_k127_6038604_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000448 256.0
PYH1_k127_6038604_3 Protein conserved in bacteria K16785 - - 0.0000000000000000000000000000000000000000000000001114 183.0
PYH1_k127_6038604_4 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000003908 166.0
PYH1_k127_6038983_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 610.0
PYH1_k127_6051369_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 323.0
PYH1_k127_6051369_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000009538 189.0
PYH1_k127_6052184_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 614.0
PYH1_k127_6052184_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 514.0
PYH1_k127_6052184_2 Glutathione S-transferase K00799,K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7,2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 505.0
PYH1_k127_6052184_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 406.0
PYH1_k127_6052184_4 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 377.0
PYH1_k127_6052184_5 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
PYH1_k127_6052184_6 ATPase activity - - - 0.000000000000000000000000000000000000000000000009058 178.0
PYH1_k127_6054032_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.209e-285 888.0
PYH1_k127_6054032_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
PYH1_k127_6054032_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000000003166 239.0
PYH1_k127_6059526_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000006822 70.0
PYH1_k127_6059526_1 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.000001435 54.0
PYH1_k127_6067371_0 FtsX-like permease family K02004 - - 7.08e-242 762.0
PYH1_k127_6067371_1 Peptidase family M1 domain K08776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 437.0
PYH1_k127_6068931_0 - - - - 0.000000000000000000000000000000000000000000000000001293 192.0
PYH1_k127_6074156_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 5.104e-223 700.0
PYH1_k127_6074156_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 374.0
PYH1_k127_6074156_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 346.0
PYH1_k127_6074156_3 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 332.0
PYH1_k127_6074156_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
PYH1_k127_6074156_5 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000006731 188.0
PYH1_k127_6074156_6 pilus assembly protein PilW K02672 - - 0.000000000000000000000000000000000000000000007919 171.0
PYH1_k127_6074156_7 Putative Competence protein ComGF K02246,K02248 - - 0.0000000000000000000000000000008183 128.0
PYH1_k127_6074156_8 response regulator K03413 - - 0.00000000000000000000000000002159 120.0
PYH1_k127_6074156_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0001028 45.0
PYH1_k127_6081331_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001679 243.0
PYH1_k127_6081331_1 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000000000001577 205.0
PYH1_k127_6081331_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000001731 151.0
PYH1_k127_6081331_3 bile acid:sodium symporter activity K03453 - - 0.00000000000000000000005741 109.0
PYH1_k127_608401_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 536.0
PYH1_k127_608401_1 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 303.0
PYH1_k127_608401_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 291.0
PYH1_k127_608401_3 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003751 282.0
PYH1_k127_6094515_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1677.0
PYH1_k127_6094515_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 487.0
PYH1_k127_6094515_2 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000001883 195.0
PYH1_k127_6097601_0 SprT homologues. K02742 - - 0.00000000000000000004397 99.0
PYH1_k127_6098551_0 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 408.0
PYH1_k127_6098551_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
PYH1_k127_6098551_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000009683 197.0
PYH1_k127_6098551_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000008499 148.0
PYH1_k127_6101546_0 PFAM Transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 566.0
PYH1_k127_6101546_1 Glyoxalase-like domain - - - 0.00001043 49.0
PYH1_k127_6106218_0 Belongs to the aldehyde dehydrogenase family K00130,K00135,K00146,K22187 - 1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79,1.2.1.8 2.525e-252 790.0
PYH1_k127_6106218_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 596.0
PYH1_k127_6106218_10 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.000000000000000003107 93.0
PYH1_k127_6106218_2 Protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 554.0
PYH1_k127_6106218_3 nitric oxide reductase activity K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 394.0
PYH1_k127_6106218_4 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 372.0
PYH1_k127_6106218_5 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007283 271.0
PYH1_k127_6106218_6 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006651 281.0
PYH1_k127_6106218_7 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
PYH1_k127_6106218_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000007137 153.0
PYH1_k127_6106218_9 Endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000003378 113.0
PYH1_k127_6110397_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 543.0
PYH1_k127_6110397_1 DNA polymerase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 495.0
PYH1_k127_6110397_2 similarity to GB AAB68949.1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 433.0
PYH1_k127_6110397_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 321.0
PYH1_k127_6110397_4 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000001095 223.0
PYH1_k127_6110397_5 Membrane K08988 - - 0.000000000000000000000000000000000000000000000000000000002637 206.0
PYH1_k127_6110397_7 - - - - 0.0000000000000000000000387 104.0
PYH1_k127_6112418_0 Histidine kinase K02482 - 2.7.13.3 0.0000000000000001292 93.0
PYH1_k127_6112905_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 546.0
PYH1_k127_6112905_1 Ion channel - - - 0.00000000000000000000000000000001946 134.0
PYH1_k127_6116580_0 ABC transporter K06147 - - 7.609e-200 647.0
PYH1_k127_6116580_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000001652 258.0
PYH1_k127_6116580_2 Response regulator, receiver - - - 0.000000000000000001724 91.0
PYH1_k127_6127216_0 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 287.0
PYH1_k127_6127216_1 MOSC domain - - - 0.00000000000000000000000000000000000000000000003164 173.0
PYH1_k127_6129187_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 330.0
PYH1_k127_6129187_1 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000004575 122.0
PYH1_k127_6129187_2 - - - - 0.000000000000000000000000004843 115.0
PYH1_k127_6129187_3 Pfam Integrase core domain - - - 0.000000000000000149 79.0
PYH1_k127_6141287_0 reverse transcriptase K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 435.0
PYH1_k127_6141287_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000000000000000000000000000001317 206.0
PYH1_k127_6141786_0 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 387.0
PYH1_k127_6141786_1 Protein of unknown function (DUF1254) - - - 0.0000000000000009582 79.0
PYH1_k127_6154313_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.596e-228 713.0
PYH1_k127_6154313_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 439.0
PYH1_k127_6154313_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
PYH1_k127_6161144_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 484.0
PYH1_k127_6161144_1 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000001107 172.0
PYH1_k127_6161144_2 pyruvate decarboxylase activity K04103 - 4.1.1.74 0.000000000000000000000000000000000000000005851 159.0
PYH1_k127_6163880_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.747e-222 693.0
PYH1_k127_6163880_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 391.0
PYH1_k127_6163880_2 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
PYH1_k127_6163880_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000001888 231.0
PYH1_k127_6163880_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000006199 207.0
PYH1_k127_6169334_0 resolution of meiotic recombination intermediates K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 429.0
PYH1_k127_6169334_1 wobble position uridine ribose methylation K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 275.0
PYH1_k127_6174363_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 - - - 1.252e-199 628.0
PYH1_k127_6174363_1 PFAM CopG domain protein DNA-binding domain protein K18918 - - 0.0000000003601 61.0
PYH1_k127_6183898_0 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000008022 228.0
PYH1_k127_6183898_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000007888 138.0
PYH1_k127_6183898_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000001433 72.0
PYH1_k127_619390_0 Autoinducer binding domain K20334 - - 0.0000000000000000000000000000000007924 141.0
PYH1_k127_619390_1 Acyl-homoserine-lactone synthase K13060,K13061,K18096,K20248,K20249,K20250 - 2.3.1.184,2.3.1.228,2.3.1.229 0.0000001449 55.0
PYH1_k127_6195403_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1353.0
PYH1_k127_6195403_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 408.0
PYH1_k127_6196158_0 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000001221 166.0
PYH1_k127_6196158_1 HicB_like antitoxin of bacterial toxin-antitoxin system K18843 - - 0.0000000000000000000000000000000000001719 143.0
PYH1_k127_6198244_0 Resolvase K06400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009346 287.0
PYH1_k127_6198244_1 Resolvase K06400 - - 0.000000000000000000000000003452 119.0
PYH1_k127_6198244_2 Winged helix-turn helix - - - 0.00000000000000000000000005274 114.0
PYH1_k127_6201176_0 - - - - 7.338e-207 644.0
PYH1_k127_6201176_1 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002885 181.0
PYH1_k127_6201176_2 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000003071 157.0
PYH1_k127_6218618_0 Transposase K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 297.0
PYH1_k127_6218618_1 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000007581 60.0
PYH1_k127_6232421_0 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 497.0
PYH1_k127_6232421_1 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 289.0
PYH1_k127_6232421_2 metal cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 291.0
PYH1_k127_6232421_3 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005496 280.0
PYH1_k127_6232421_4 Ubiquinol--cytochrome c reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007694 239.0
PYH1_k127_6232421_6 Zn peptidase - - - 0.00000000000000000000000000000000000003505 144.0
PYH1_k127_6232421_7 Phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000007675 128.0
PYH1_k127_6238042_0 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 547.0
PYH1_k127_6245204_0 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000003165 193.0
PYH1_k127_62459_0 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000000000000000000000009273 180.0
PYH1_k127_62459_1 Transposase K07497 - - 0.0000000000000000000000000000000000003604 141.0
PYH1_k127_62459_2 PFAM Integrase catalytic region K07497 - - 0.00000000000000001217 84.0
PYH1_k127_6255444_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 2.942e-200 627.0
PYH1_k127_6262954_0 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
PYH1_k127_6262954_1 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000002381 165.0
PYH1_k127_6262954_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000002631 108.0
PYH1_k127_6262954_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000009247 100.0
PYH1_k127_6262954_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000008714 73.0
PYH1_k127_6264126_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.415e-198 623.0
PYH1_k127_6264126_1 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 345.0
PYH1_k127_6264126_2 Actin K03569 - - 0.000000000000000000000000000000000000000000000002501 173.0
PYH1_k127_6279678_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 398.0
PYH1_k127_6284662_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 278.0
PYH1_k127_6284662_1 PFAM Polysaccharide deacetylase - - - 0.00000000004039 65.0
PYH1_k127_6284730_0 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 487.0
PYH1_k127_6284730_3 Cupin 2, conserved barrel domain protein - - - 0.0000004408 51.0
PYH1_k127_6302928_0 iron dependent repressor - - - 0.00000000000000000000000000000000000000001448 172.0
PYH1_k127_6315066_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 523.0
PYH1_k127_6319904_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 343.0
PYH1_k127_6319904_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 338.0
PYH1_k127_6319904_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001153 235.0
PYH1_k127_6319904_3 peptidyl-tyrosine sulfation - - - 0.0000000002724 65.0
PYH1_k127_6324039_0 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 313.0
PYH1_k127_6339731_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1663.0
PYH1_k127_6339731_1 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 483.0
PYH1_k127_6339731_11 Integrase core domain K07497 - - 0.0000000001439 63.0
PYH1_k127_6339731_12 Evidence 2b Function of strongly homologous gene - - - 0.000001301 51.0
PYH1_k127_6339731_13 HTH-like domain K07497 - - 0.000006437 49.0
PYH1_k127_6339731_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 454.0
PYH1_k127_6339731_3 membrane K08976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
PYH1_k127_6339731_4 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 345.0
PYH1_k127_6339731_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002099 232.0
PYH1_k127_6339731_7 antisigma factor binding K03598 - - 0.0000000000000000000000000000896 123.0
PYH1_k127_6339731_8 similarity to OMNI NTL01RS2573 K07485 - - 0.000000000000000000005958 94.0
PYH1_k127_6341261_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 299.0
PYH1_k127_6341261_1 Domain of unknown function (DUF4410) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009004 256.0
PYH1_k127_6341261_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000004228 183.0
PYH1_k127_6341261_3 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000003646 135.0
PYH1_k127_6341261_4 - - - - 0.0000000000000000000000000000001253 127.0
PYH1_k127_6341261_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000002939 122.0
PYH1_k127_6341261_6 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000007755 71.0
PYH1_k127_63496_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 590.0
PYH1_k127_63496_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000001474 188.0
PYH1_k127_6354774_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 297.0
PYH1_k127_6356280_0 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.0000000000000000000000002808 121.0
PYH1_k127_6356280_1 Parallel beta-helix repeats - - - 0.000000000000000000000004708 104.0
PYH1_k127_6360454_0 High confidence in function and specificity - - - 3.307e-235 750.0
PYH1_k127_6367306_0 general secretion pathway protein K02246,K02247,K02456,K02457,K02458,K10924 - - 0.000000000005588 72.0
PYH1_k127_6367306_1 Prokaryotic N-terminal methylation motif K02458 - - 0.00000858 54.0
PYH1_k127_6367306_2 Prokaryotic N-terminal methylation motif K02457,K02458,K02459,K02655,K10926 - - 0.0003668 51.0
PYH1_k127_6391303_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 466.0
PYH1_k127_6397417_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.158e-304 941.0
PYH1_k127_6397417_1 Belongs to the Fur family K09825 - - 0.00000001672 60.0
PYH1_k127_6397417_2 Ferric uptake regulator, Fur family K09825 - - 0.0000001271 55.0
PYH1_k127_640377_0 Rieske [2Fe-2S] domain K15982 - 1.14.13.142 0.000000000000000000000000000002213 132.0
PYH1_k127_6422829_0 - - - - 1.268e-295 914.0
PYH1_k127_6422829_1 PFAM PfkB K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 432.0
PYH1_k127_6422829_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 346.0
PYH1_k127_6451203_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 3.222e-263 820.0
PYH1_k127_6451203_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001163 224.0
PYH1_k127_6451203_2 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000032 184.0
PYH1_k127_6451203_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000004963 147.0
PYH1_k127_6454928_0 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 595.0
PYH1_k127_6454928_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002011 262.0
PYH1_k127_6454928_2 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000003561 197.0
PYH1_k127_6467908_0 response to oxidative stress K04063 - - 0.000000000000000000000000000000000000000000000000000000000000000000008319 235.0
PYH1_k127_6467908_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001477 209.0
PYH1_k127_6467908_2 Cytochrome c K12263 - - 0.00000000000000000000000000003506 120.0
PYH1_k127_6467908_3 Superoxide dismutase K04565 - 1.15.1.1 0.00000000000000000001521 96.0
PYH1_k127_6467908_4 Cytochrome c K12263 - - 0.0000000000209 65.0
PYH1_k127_64841_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1473.0
PYH1_k127_64841_1 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0 1060.0
PYH1_k127_64841_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 2.168e-267 829.0
PYH1_k127_64841_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 369.0
PYH1_k127_64841_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004076 255.0
PYH1_k127_64841_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002479 214.0
PYH1_k127_64841_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000001743 167.0
PYH1_k127_64841_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000139 53.0
PYH1_k127_6487137_0 phosphorelay signal transduction system K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 506.0
PYH1_k127_6487137_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 424.0
PYH1_k127_6488222_0 COG2015, Alkyl sulfatase and related hydrolases - - - 3.207e-314 975.0
PYH1_k127_6488222_1 Sulfatase K01130 - 3.1.6.1 3.157e-231 721.0
PYH1_k127_6488222_2 Conserved Protein - - - 0.000000000000000000000000000000001268 134.0
PYH1_k127_6491661_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 402.0
PYH1_k127_6491661_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000172 135.0
PYH1_k127_6503198_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.311e-270 835.0
PYH1_k127_6503198_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 477.0
PYH1_k127_6503198_2 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000001979 195.0
PYH1_k127_6503198_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000004257 101.0
PYH1_k127_6508279_0 Trap dicarboxylate transporter, dctm subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 529.0
PYH1_k127_6508279_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000001765 212.0
PYH1_k127_6508279_2 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.00000000000000000000000000000000000002582 147.0
PYH1_k127_65230_0 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 454.0
PYH1_k127_6558282_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002136 278.0
PYH1_k127_6558282_1 - - - - 0.000000000000005526 79.0
PYH1_k127_65876_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1050.0
PYH1_k127_65876_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 1.642e-257 801.0
PYH1_k127_65876_2 B3/4 domain K01890 - 6.1.1.20 5.077e-246 771.0
PYH1_k127_65876_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 341.0
PYH1_k127_65876_4 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 287.0
PYH1_k127_65876_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001586 196.0
PYH1_k127_65876_6 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000002829 168.0
PYH1_k127_65876_7 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002613 80.0
PYH1_k127_6603152_0 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 300.0
PYH1_k127_6603152_1 Cyclic nucleotide-monophosphate binding domain K07001 - - 0.0000003671 62.0
PYH1_k127_667320_0 Aminotransferase class I and II K14261 - - 8.179e-235 729.0
PYH1_k127_667320_1 Homoserine dehydrogenase K00003 - 1.1.1.3 6.89e-223 696.0
PYH1_k127_667320_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 592.0
PYH1_k127_667320_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 394.0
PYH1_k127_667320_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000002071 141.0
PYH1_k127_667710_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
PYH1_k127_667710_1 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002219 220.0
PYH1_k127_6707122_0 Protein of unknown function (DUF1298) - - - 1.72e-237 746.0
PYH1_k127_6707122_1 Protein of unknown function (DUF2846) - - - 0.000000000000000000005589 99.0
PYH1_k127_6707122_2 - - - - 0.0000682 47.0
PYH1_k127_6708589_0 tail specific protease K03797 - 3.4.21.102 5.782e-212 667.0
PYH1_k127_6708589_1 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
PYH1_k127_6708589_2 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000000000000000001573 138.0
PYH1_k127_6714088_0 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000006027 149.0
PYH1_k127_6714088_1 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00000000000000162 76.0
PYH1_k127_6714088_2 Protein of unknown function (DUF521) K09123 - - 0.00000000000003479 76.0
PYH1_k127_6716744_0 silver ion transport K15726 - - 0.0 1379.0
PYH1_k127_6716744_1 Multicopper oxidase type 1 - - - 7.143e-261 816.0
PYH1_k127_6716744_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 432.0
PYH1_k127_6716744_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 379.0
PYH1_k127_6716744_4 AMP binding - - - 0.0000000000000000000000000000003521 124.0
PYH1_k127_6731703_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 446.0
PYH1_k127_6731703_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000001963 188.0
PYH1_k127_6731703_2 Glycosyltransferase like family 2 K20444 - - 0.000000003243 63.0
PYH1_k127_6733689_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.153e-241 749.0
PYH1_k127_6733689_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006121 276.0
PYH1_k127_6733689_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000107 240.0
PYH1_k127_6733689_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000002802 128.0
PYH1_k127_6737099_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000003412 174.0
PYH1_k127_6737099_1 Cadherin-like - - - 0.00000000000000000000000000003598 131.0
PYH1_k127_6737099_2 ATP-binding region ATPase domain protein K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000002204 76.0
PYH1_k127_6737099_3 Putative Ig domain - - - 0.000005686 58.0
PYH1_k127_6748644_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 312.0
PYH1_k127_6748644_1 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000202 236.0
PYH1_k127_6750353_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 507.0
PYH1_k127_6750353_1 Psort location Cytoplasmic, score K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 472.0
PYH1_k127_6759194_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 530.0
PYH1_k127_6759194_1 Evidence 2b Function of strongly homologous gene K04752 - - 0.0000000000000000000000004908 107.0
PYH1_k127_6770777_0 transposase K07492 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
PYH1_k127_6770777_1 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.000000000000000000000000000000000000000003702 162.0
PYH1_k127_6771597_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 4.128e-216 695.0
PYH1_k127_6771597_1 Phosphotriesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 398.0
PYH1_k127_6771597_10 Polar amino acid ABC transporter, inner membrane K02029 - - 0.00000000000000000000000000001063 132.0
PYH1_k127_6771597_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000004179 108.0
PYH1_k127_6771597_2 Bacterial periplasmic substrate-binding proteins K02030,K02424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 332.0
PYH1_k127_6771597_3 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 318.0
PYH1_k127_6771597_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002064 284.0
PYH1_k127_6771597_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000005518 252.0
PYH1_k127_6771597_6 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002275 199.0
PYH1_k127_6771597_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000006021 184.0
PYH1_k127_6771597_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000279 173.0
PYH1_k127_6771597_9 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000006822 134.0
PYH1_k127_67732_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004535 287.0
PYH1_k127_67732_1 - - - - 0.00008467 50.0
PYH1_k127_6776987_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 5.401e-256 790.0
PYH1_k127_6776987_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 325.0
PYH1_k127_6776987_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 288.0
PYH1_k127_6780831_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 523.0
PYH1_k127_6780831_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 293.0
PYH1_k127_6780831_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000008514 235.0
PYH1_k127_6780831_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000001202 112.0
PYH1_k127_6780831_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000007478 58.0
PYH1_k127_6783113_0 Transposase Tn5 dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 528.0
PYH1_k127_6789969_0 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 5.462e-238 739.0
PYH1_k127_6789969_1 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 357.0
PYH1_k127_6789969_2 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 336.0
PYH1_k127_6789969_5 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000002057 128.0
PYH1_k127_6791140_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000003103 223.0
PYH1_k127_6791140_1 Methyltransferase K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000005767 173.0
PYH1_k127_6791140_2 Nacht domain - - - 0.000000000000000000000000000000000003235 152.0
PYH1_k127_6791140_3 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000008379 137.0
PYH1_k127_6791140_4 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.0000000000000000000000000000000004129 137.0
PYH1_k127_6791140_5 Cupin - - - 0.00000000007374 69.0
PYH1_k127_6791333_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1050.0
PYH1_k127_6791333_1 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 531.0
PYH1_k127_6791333_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 385.0
PYH1_k127_6791333_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 340.0
PYH1_k127_6791333_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000006399 216.0
PYH1_k127_6791333_5 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000106 160.0
PYH1_k127_6791495_0 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 476.0
PYH1_k127_6791495_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 344.0
PYH1_k127_6791495_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 316.0
PYH1_k127_6791495_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002294 233.0
PYH1_k127_6791495_4 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000006625 149.0
PYH1_k127_6791495_5 Rieske (2fe-2S) - - - 0.00000000000000000000000000000000000001689 145.0
PYH1_k127_6791495_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000003539 113.0
PYH1_k127_6792168_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 341.0
PYH1_k127_6793009_0 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 420.0
PYH1_k127_6793009_1 Sulfate ABC transporter, inner membrane subunit CysW K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 413.0
PYH1_k127_6793009_2 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 292.0
PYH1_k127_6793009_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 287.0
PYH1_k127_6795140_0 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 9.225e-194 607.0
PYH1_k127_6795140_1 protein complex oligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 531.0
PYH1_k127_6795140_2 peptidase K02557,K21471 - - 0.0000000000000000000000000000000000000000000009965 176.0
PYH1_k127_6795140_3 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001769 157.0
PYH1_k127_6795140_4 YHYH protein - - - 0.00000000000000000000000000000000000001326 149.0
PYH1_k127_6795140_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000002434 72.0
PYH1_k127_6795140_6 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000003092 56.0
PYH1_k127_6795309_0 alpha-ribazole phosphatase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000001411 233.0
PYH1_k127_6795309_1 (Barnase) inhibitor - - - 0.000000000000000000000000000000000000000000003694 169.0
PYH1_k127_6795309_2 endoribonuclease activity K03628,K15125 GO:0005575,GO:0005576 - 0.000000000000000000000000002006 117.0
PYH1_k127_6795309_4 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0004317 43.0
PYH1_k127_6797180_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 537.0
PYH1_k127_6797180_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 516.0
PYH1_k127_6797180_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 482.0
PYH1_k127_6797180_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 440.0
PYH1_k127_6797180_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 369.0
PYH1_k127_6797180_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000006395 236.0
PYH1_k127_6797180_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000003071 188.0
PYH1_k127_6805392_0 Transposase DDE domain - - - 0.0000000000000000000000002457 120.0
PYH1_k127_6805392_1 Eco57I restriction endonuclease K07317 - 2.1.1.72 0.0000000000000000000000005911 105.0
PYH1_k127_6805392_2 XamI restriction endonuclease - - - 0.00000000004749 64.0
PYH1_k127_681009_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 336.0
PYH1_k127_6815229_0 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001112 184.0
PYH1_k127_6815229_1 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000000000002711 147.0
PYH1_k127_6822243_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 4.663e-272 857.0
PYH1_k127_6822243_1 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 447.0
PYH1_k127_6822243_10 Cytochrome c K00406 - - 0.0000000000000007214 83.0
PYH1_k127_6822243_11 Helix-turn-helix XRE-family like proteins K21498 - - 0.0002207 45.0
PYH1_k127_6822243_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002078 274.0
PYH1_k127_6822243_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000003368 231.0
PYH1_k127_6822243_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.00000000000000000000000000000000000000000000000000008123 188.0
PYH1_k127_6822243_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000000000000000000000000000000006228 183.0
PYH1_k127_6822243_7 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000001703 160.0
PYH1_k127_6822243_8 Cytochrome c K02305,K17223 - - 0.00000000000000000000000000001201 124.0
PYH1_k127_6822243_9 Phosphoribosyl transferase domain - - - 0.0000000000000000000000001704 106.0
PYH1_k127_6829788_0 Trypsin K04771 - 3.4.21.107 5.333e-234 734.0
PYH1_k127_6829788_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 4.221e-195 610.0
PYH1_k127_6829788_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 511.0
PYH1_k127_6829788_3 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 371.0
PYH1_k127_6829968_0 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 565.0
PYH1_k127_6829968_1 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 531.0
PYH1_k127_6829968_2 heat shock protein binding K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 306.0
PYH1_k127_6833806_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 509.0
PYH1_k127_6833806_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 363.0
PYH1_k127_6833806_2 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 288.0
PYH1_k127_6833806_3 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003251 261.0
PYH1_k127_6833806_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000001441 144.0
PYH1_k127_6833806_5 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000001967 116.0
PYH1_k127_6838650_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 481.0
PYH1_k127_6838650_1 PFAM ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
PYH1_k127_6838650_2 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 335.0
PYH1_k127_6838650_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 269.0
PYH1_k127_6844613_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 455.0
PYH1_k127_6853690_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.517e-194 625.0
PYH1_k127_6853690_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 280.0
PYH1_k127_6853690_11 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003922 273.0
PYH1_k127_6853690_12 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001237 280.0
PYH1_k127_6853690_13 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000007724 265.0
PYH1_k127_6853690_14 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000503 256.0
PYH1_k127_6853690_15 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000001072 250.0
PYH1_k127_6853690_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000002836 205.0
PYH1_k127_6853690_17 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000007674 198.0
PYH1_k127_6853690_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 476.0
PYH1_k127_6853690_20 - - - - 0.0000000000000000000000000000000006089 135.0
PYH1_k127_6853690_21 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000006429 120.0
PYH1_k127_6853690_22 domain, Protein K18491 - - 0.000000000000000000084 97.0
PYH1_k127_6853690_24 Domain of unknown function (DUF4258) - - - 0.0009967 46.0
PYH1_k127_6853690_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 466.0
PYH1_k127_6853690_4 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 417.0
PYH1_k127_6853690_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 398.0
PYH1_k127_6853690_6 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 374.0
PYH1_k127_6853690_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 356.0
PYH1_k127_6853690_8 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
PYH1_k127_6853690_9 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 314.0
PYH1_k127_6853887_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 332.0
PYH1_k127_6853887_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 304.0
PYH1_k127_6855498_0 Rubrerythrin K22405 - 1.6.3.4 5.981e-316 973.0
PYH1_k127_6855498_1 Iron-sulfur cluster-binding domain - - - 1.754e-236 733.0
PYH1_k127_6859794_0 DNA topoisomerase II activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 480.0
PYH1_k127_6862508_0 DNA polymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 587.0
PYH1_k127_6868280_0 DnaJ molecular chaperone homology domain K04082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003875 276.0
PYH1_k127_6868280_1 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000000000000000000000000000000002155 182.0
PYH1_k127_6869949_0 - - - - 0.00000000000000000000000000000000002257 138.0
PYH1_k127_6869949_1 - - - - 0.000000000000000000000002342 106.0
PYH1_k127_6869949_2 - - - - 0.00000000000000000002074 91.0
PYH1_k127_6869949_3 ORF located using Blastx - - - 0.000000000004053 68.0
PYH1_k127_6869949_4 - - - - 0.00000000003256 63.0
PYH1_k127_6869949_5 ORF located using Blastx - - - 0.000000006998 61.0
PYH1_k127_6869949_7 - - - - 0.0000002634 53.0
PYH1_k127_6871033_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.971e-210 657.0
PYH1_k127_6871033_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 3.207e-194 610.0
PYH1_k127_6871033_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 471.0
PYH1_k127_6871033_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 466.0
PYH1_k127_6871033_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000003769 167.0
PYH1_k127_6871033_5 Stage II sporulation protein K06381 - - 0.000000000000000000001761 101.0
PYH1_k127_6871033_6 Protein of unknown function (DUF2905) - - - 0.000000000000000000009368 94.0
PYH1_k127_6874040_0 alpha-ribazole phosphatase activity K00850,K21071 - 2.7.1.11,2.7.1.90 9.4e-323 996.0
PYH1_k127_6874040_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.326e-220 694.0
PYH1_k127_6874040_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 297.0
PYH1_k127_6880577_0 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 519.0
PYH1_k127_6880577_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 287.0
PYH1_k127_6885907_0 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000003792 264.0
PYH1_k127_6885907_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000005622 170.0
PYH1_k127_6885907_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000002868 155.0
PYH1_k127_6900741_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 3.068e-303 938.0
PYH1_k127_6900741_1 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001879 201.0
PYH1_k127_6900741_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000006185 147.0
PYH1_k127_6900741_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000154 64.0
PYH1_k127_6907993_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 1.219e-309 965.0
PYH1_k127_6907993_1 Peptidase M15 K02395 - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
PYH1_k127_6907993_2 phosphorelay signal transduction system K02535 - 3.5.1.108 0.000000002666 59.0
PYH1_k127_6912232_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 2.373e-222 700.0
PYH1_k127_6912232_1 Cytochrome c K07245,K14166 - - 0.00002436 52.0
PYH1_k127_6923116_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 476.0
PYH1_k127_6925180_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000005325 116.0
PYH1_k127_6925180_1 ribosylpyrimidine nucleosidase activity - - - 0.000000006085 70.0
PYH1_k127_6925675_0 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002986 274.0
PYH1_k127_6925675_1 Helix-hairpin-helix motif - - - 0.000000000000000000000131 102.0
PYH1_k127_6930068_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 617.0
PYH1_k127_6930068_1 - - - - 0.00000000000000000000000000001598 125.0
PYH1_k127_6941943_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000003678 183.0
PYH1_k127_6941943_1 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000003969 101.0
PYH1_k127_6945813_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 5.803e-243 757.0
PYH1_k127_6945813_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 2.799e-213 675.0
PYH1_k127_6945813_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 1.381e-201 639.0
PYH1_k127_6945813_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 607.0
PYH1_k127_6945813_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 601.0
PYH1_k127_6945813_5 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 531.0
PYH1_k127_6945813_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 416.0
PYH1_k127_6952981_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 464.0
PYH1_k127_6952981_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000001164 237.0
PYH1_k127_6956446_0 Transposase and inactivated derivatives K00986,K07497 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 445.0
PYH1_k127_6956446_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000002625 182.0
PYH1_k127_6968304_0 - - - - 0.00000000000000000000000000000000000003186 164.0
PYH1_k127_6968304_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01303 - 3.4.19.1 0.00000001143 61.0
PYH1_k127_6979189_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 516.0
PYH1_k127_7005907_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 2.213e-215 671.0
PYH1_k127_7005907_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 442.0
PYH1_k127_7007916_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 2.399e-227 712.0
PYH1_k127_7007916_1 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 589.0
PYH1_k127_7007916_2 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 571.0
PYH1_k127_7034180_0 Ftsk_gamma K03466 - - 6.382e-265 829.0
PYH1_k127_7034180_1 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 288.0
PYH1_k127_7034180_2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.0000000000000000000000000000000000006565 141.0
PYH1_k127_7036208_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 6.473e-264 820.0
PYH1_k127_7039469_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 537.0
PYH1_k127_7039469_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 411.0
PYH1_k127_7039469_2 PFAM IS66 Orf2 family protein K07484 - - 0.000000000000000000000000000000000000002444 151.0
PYH1_k127_7039469_3 PFAM Resolvase - - - 0.00000000000000000000000000000000000465 139.0
PYH1_k127_7039469_4 - - - - 0.0000000000005538 75.0
PYH1_k127_7040992_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 465.0
PYH1_k127_7040992_1 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000003554 168.0
PYH1_k127_7040992_3 Transposase K07483 - - 0.0000000000000000000000000000000000001017 143.0
PYH1_k127_7042202_0 Sulfatase - - - 7.544e-275 852.0
PYH1_k127_7042202_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 511.0
PYH1_k127_7042202_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009193 256.0
PYH1_k127_7042202_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000004354 168.0
PYH1_k127_7042202_4 - - - - 0.000000000000001047 80.0
PYH1_k127_7044170_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1161.0
PYH1_k127_7044170_1 PFAM SNF2-related protein - - - 2.958e-239 782.0
PYH1_k127_7044170_2 DHH family K07462 - - 3.548e-225 708.0
PYH1_k127_7044170_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
PYH1_k127_7044170_4 metalloendopeptidase activity K08602 - - 0.00000000000000000000000000000000000000000000000000000000004952 206.0
PYH1_k127_7044170_5 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000002241 188.0
PYH1_k127_7044170_7 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000000005855 85.0
PYH1_k127_7044170_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0001668 44.0
PYH1_k127_7050724_0 drug transmembrane transporter activity K03327 - - 1.332e-205 649.0
PYH1_k127_7050724_1 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 2.572e-194 618.0
PYH1_k127_7050724_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000002132 147.0
PYH1_k127_7050724_3 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000002586 153.0
PYH1_k127_7050724_4 Thioredoxin domain - - - 0.0000000000000000000000000000000000006995 139.0
PYH1_k127_7061500_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000002595 229.0
PYH1_k127_7061500_1 MEKHLA domain - - - 0.000000000000000000000000000000000000009416 145.0
PYH1_k127_7061500_2 Protein conserved in bacteria K09705 - - 0.000000000000000000000001309 105.0
PYH1_k127_707607_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000007331 198.0
PYH1_k127_707607_1 transposase activity K07483 - - 0.000000000000000000001971 97.0
PYH1_k127_707607_2 Immune inhibitor A peptidase M6 K09607 - - 0.000003721 52.0
PYH1_k127_7085611_0 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001143 259.0
PYH1_k127_7085611_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000004737 64.0
PYH1_k127_7085611_2 PFAM Integrase catalytic region K07497 - - 0.000000001987 64.0
PYH1_k127_7089781_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.791e-233 722.0
PYH1_k127_7097140_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 385.0
PYH1_k127_7103739_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 539.0
PYH1_k127_7103739_1 VIT family - - - 0.000000000000000000000000009991 122.0
PYH1_k127_7103751_0 DNA topoisomerase II activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002908 255.0
PYH1_k127_7103751_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000007095 221.0
PYH1_k127_7104523_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 407.0
PYH1_k127_7114411_0 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
PYH1_k127_7114411_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000008707 89.0
PYH1_k127_7114411_2 - - - - 0.000009161 49.0
PYH1_k127_7119883_0 cell redox homeostasis K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 480.0
PYH1_k127_7119883_1 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000003114 244.0
PYH1_k127_7119883_2 transcriptional regulator K03717 - - 0.00000000000000000000000005009 109.0
PYH1_k127_7119883_3 Phosphate-starvation-inducible E - - - 0.0003498 50.0
PYH1_k127_7122748_0 Transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 360.0
PYH1_k127_7123085_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.592e-260 812.0
PYH1_k127_7139284_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 307.0
PYH1_k127_7139284_1 Evidence 2b Function of strongly homologous gene K02003 - - 0.000000000000000000000000000000000000000000000000000000000003171 209.0
PYH1_k127_7145916_0 Phosphate acyltransferases K01897,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3 1.056e-204 646.0
PYH1_k127_7153309_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 411.0
PYH1_k127_7153309_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 388.0
PYH1_k127_7163_0 Bacterial regulatory protein, Fis family K07714 - - 1.427e-219 689.0
PYH1_k127_7163_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 477.0
PYH1_k127_7163_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
PYH1_k127_7163_3 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
PYH1_k127_7163_4 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000003518 93.0
PYH1_k127_7163_5 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000003595 63.0
PYH1_k127_7167193_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 379.0
PYH1_k127_7181084_0 NHL repeat - - - 7.897e-240 744.0
PYH1_k127_7181084_1 denitrification pathway - - - 3.803e-222 694.0
PYH1_k127_7181084_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 454.0
PYH1_k127_7181084_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000005847 61.0
PYH1_k127_7181084_5 denitrification pathway - - - 0.000001952 52.0
PYH1_k127_7212711_0 ATP citrate lyase citrate-binding K15231 - 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 475.0
PYH1_k127_7212711_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 368.0
PYH1_k127_7237021_0 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000001284 198.0
PYH1_k127_7237021_1 - - - - 0.0000000000000000000000000000000000000005103 154.0
PYH1_k127_7237021_2 Peptidase family M48 - - - 0.000000000000000000000000000000004859 140.0
PYH1_k127_7237021_3 Domain of unknown function (DUF4136) - - - 0.000000000000000006889 91.0
PYH1_k127_7237021_4 Domain of unknown function (DUF4136) - - - 0.0009642 46.0
PYH1_k127_7240089_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 425.0
PYH1_k127_7240089_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
PYH1_k127_7245309_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 8.394e-263 815.0
PYH1_k127_7245309_1 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 3.419e-249 798.0
PYH1_k127_7245309_2 fructose-bisphosphate aldolase activity K01622 - 3.1.3.11,4.1.2.13 4.315e-228 709.0
PYH1_k127_7245309_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 332.0
PYH1_k127_7245309_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000003871 178.0
PYH1_k127_7245309_6 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.000000000000000000000000000000000005233 141.0
PYH1_k127_7245309_7 Belongs to the universal stress protein A family - - - 0.00000000000000007795 81.0
PYH1_k127_7253955_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 297.0
PYH1_k127_7253955_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001007 254.0
PYH1_k127_7253955_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000001461 166.0
PYH1_k127_7260614_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 288.0
PYH1_k127_7260614_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000006086 62.0
PYH1_k127_7261393_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 441.0
PYH1_k127_7261393_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000222 107.0
PYH1_k127_7262274_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 456.0
PYH1_k127_7263_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 474.0
PYH1_k127_7272459_0 transposition, DNA-mediated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 378.0
PYH1_k127_7276353_0 stress-induced mitochondrial fusion K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 536.0
PYH1_k127_7276353_1 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 484.0
PYH1_k127_7276353_2 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 333.0
PYH1_k127_7276353_3 Phosphate transporter family K03306 - - 0.00000000000000000001459 91.0
PYH1_k127_7277449_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 256.0
PYH1_k127_7277449_1 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000004675 143.0
PYH1_k127_7277449_2 glycogen debranching - - - 0.00000000001881 66.0
PYH1_k127_7277449_3 Helix-turn-helix domain - - - 0.0000009923 55.0
PYH1_k127_7311552_0 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 299.0
PYH1_k127_7324389_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 4.572e-251 781.0
PYH1_k127_7324389_1 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 585.0
PYH1_k127_7324389_2 cheY-homologous receiver domain - - - 0.00000000000000000004511 89.0
PYH1_k127_7340343_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001091 255.0
PYH1_k127_7344370_0 - - - - 7.467e-239 751.0
PYH1_k127_7344670_0 biopolymer transport protein K03559 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001772 182.0
PYH1_k127_7344670_1 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000001887 108.0
PYH1_k127_7344670_2 protein flavinylation K03734 - 2.7.1.180 0.0000000000001373 71.0
PYH1_k127_7344670_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000008738 57.0
PYH1_k127_7369860_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 332.0
PYH1_k127_7369860_1 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008475 272.0
PYH1_k127_7369860_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000003174 72.0
PYH1_k127_7373694_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 406.0
PYH1_k127_7432386_0 reverse transcriptase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 319.0
PYH1_k127_7485250_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 576.0
PYH1_k127_7485250_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000292 273.0
PYH1_k127_7485250_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000001368 147.0
PYH1_k127_7505471_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 384.0
PYH1_k127_7505659_0 transposition K07497 - - 0.0000000000000000000000000000000000000000000001156 184.0
PYH1_k127_7505659_1 aldo-keto reductase (NADP) activity K05275 - 1.1.1.65 0.0000000000000000000000000000000000000001148 154.0
PYH1_k127_7505659_2 23S rRNA-intervening sequence protein - - - 0.00000000889 58.0
PYH1_k127_7548580_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 610.0
PYH1_k127_7553738_0 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 295.0
PYH1_k127_7553738_1 energy transducer activity K03407,K03832 - 2.7.13.3 0.00000000000000000000000000000000000000002323 157.0
PYH1_k127_7554746_0 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000000000000000538 187.0
PYH1_k127_7554746_1 PFAM Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000001554 119.0
PYH1_k127_7554746_2 domain, Protein - - - 0.000000001039 71.0
PYH1_k127_7557106_0 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 336.0
PYH1_k127_7564894_0 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000000000000000000000000000000003167 231.0
PYH1_k127_7564894_1 transposase activity - - - 0.0000000000001959 82.0
PYH1_k127_7565929_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 375.0
PYH1_k127_7565929_1 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 308.0
PYH1_k127_7565929_2 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004242 249.0
PYH1_k127_7565929_3 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000107 94.0
PYH1_k127_7565929_4 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000682 47.0
PYH1_k127_7574312_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 323.0
PYH1_k127_7574312_1 RDD family - - - 0.00000000000000000000000000000000000000000000000000000247 194.0
PYH1_k127_7574312_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000006272 183.0
PYH1_k127_7574312_3 Actin K03569 - - 0.00000000000000000000000000000000000000002091 153.0
PYH1_k127_7577077_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 8.924e-209 657.0
PYH1_k127_7579262_0 Sulfatase K01130 - 3.1.6.1 1.633e-267 825.0
PYH1_k127_7579262_1 Pfam Sulfatase K01130 - 3.1.6.1 2.837e-217 677.0
PYH1_k127_7588092_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 323.0
PYH1_k127_7590621_0 metallopeptidase activity K03568 - - 1.738e-258 803.0
PYH1_k127_7590621_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 593.0
PYH1_k127_7590621_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000001381 227.0
PYH1_k127_7590621_3 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000000000003865 142.0
PYH1_k127_7593800_0 Phosphate acyltransferases K01897,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 501.0
PYH1_k127_7603526_0 Elements of external origin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 451.0
PYH1_k127_7604424_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.737e-234 727.0
PYH1_k127_7604424_1 MEKHLA domain - - - 0.000000000000000000000000000000000000000959 150.0
PYH1_k127_7608485_0 Elongation factor G C-terminus K06207 - - 0.0 1041.0
PYH1_k127_7608485_1 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 576.0
PYH1_k127_7608485_3 AhpC/TSA family - - - 0.000000000000000009884 83.0
PYH1_k127_7609547_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1392.0
PYH1_k127_7609547_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000005388 142.0
PYH1_k127_7610914_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 1.395e-208 657.0
PYH1_k127_7612158_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 467.0
PYH1_k127_7612158_1 Putative transposase - - - 0.00000000007634 64.0
PYH1_k127_7614251_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 465.0
PYH1_k127_7614251_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000009813 229.0
PYH1_k127_7614251_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000009209 183.0
PYH1_k127_7614251_5 acetyltransferase - - - 0.0000001002 54.0
PYH1_k127_7616233_0 - - - - 0.000000000000000000000000000000000000000005704 159.0
PYH1_k127_7616233_1 - - - - 0.0000000000000001001 82.0
PYH1_k127_7616233_2 - - - - 0.00000000000006544 74.0
PYH1_k127_7616233_3 - - - - 0.00000003844 55.0
PYH1_k127_7621731_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 4.784e-292 907.0
PYH1_k127_7621731_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 8.041e-263 816.0
PYH1_k127_7621731_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000003817 69.0
PYH1_k127_7621809_0 metallocarboxypeptidase activity K01299,K03281 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 362.0
PYH1_k127_7621809_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 311.0
PYH1_k127_7621809_2 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006121 276.0
PYH1_k127_7623541_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2035.0
PYH1_k127_7628873_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000001314 166.0
PYH1_k127_7628873_1 4 iron, 4 sulfur cluster binding - - - 0.0000000003144 63.0
PYH1_k127_7631483_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 587.0
PYH1_k127_7631483_1 Zincin-like metallopeptidase - - - 0.000000000000000000000000006602 113.0
PYH1_k127_7631483_2 Methyltransferase domain - - - 0.000000000000000000000006824 109.0
PYH1_k127_7638447_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.0 1045.0
PYH1_k127_7638447_1 Sigma-54 interaction domain K07714 - - 3.724e-218 686.0
PYH1_k127_7638447_2 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 599.0
PYH1_k127_7638447_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 469.0
PYH1_k127_7638447_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008424 259.0
PYH1_k127_7638447_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K07275,K16079 - - 0.00000000000000000000000000000000000000000001387 172.0
PYH1_k127_7638447_6 sequence-specific DNA binding - - - 0.0000000000000000000000000000007836 125.0
PYH1_k127_7638447_7 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000002293 91.0
PYH1_k127_7638447_8 Periplasmic or secreted lipoprotein - - - 0.0000000000000000002972 89.0
PYH1_k127_7642409_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006168 257.0
PYH1_k127_7642409_1 SCP-2 sterol transfer family - - - 0.000000000002146 70.0
PYH1_k127_7643447_0 Anti-sigma-K factor rskA K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 324.0
PYH1_k127_7643447_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000007544 184.0
PYH1_k127_7643447_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000005239 181.0
PYH1_k127_7646018_0 Peptidase family M1 domain K08776 - - 1.399e-197 623.0
PYH1_k127_7647237_0 Putative modulator of DNA gyrase K03592 - - 1.643e-202 639.0
PYH1_k127_7647237_1 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 425.0
PYH1_k127_7647237_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000004125 203.0
PYH1_k127_7652660_0 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 388.0
PYH1_k127_7652660_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 387.0
PYH1_k127_7652660_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 295.0
PYH1_k127_7652660_3 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000001309 155.0
PYH1_k127_7652660_4 DNA integration - - - 0.000000000000000000000000000000000000002813 150.0
PYH1_k127_7652660_5 PFAM Filamentation induced by cAMP death on curing-related K07341 - - 0.00000000000000000000000000000005046 128.0
PYH1_k127_7652660_6 PFAM SpoVT AbrB K07172,K18842 - - 0.00000000000002762 75.0
PYH1_k127_7652660_7 mRNA binding - - - 0.00000000000003623 74.0
PYH1_k127_7652671_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1043.0
PYH1_k127_7652671_1 phosphorelay signal transduction system - - - 6.967e-209 659.0
PYH1_k127_7652671_2 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 495.0
PYH1_k127_7653054_0 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.554e-232 726.0
PYH1_k127_7653054_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 481.0
PYH1_k127_7653054_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 290.0
PYH1_k127_7654868_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 287.0
PYH1_k127_7654868_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000001811 203.0
PYH1_k127_7654868_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000008959 126.0
PYH1_k127_7655880_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 420.0
PYH1_k127_7655880_1 uroporphyrinogen-III synthase activity K01719,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 368.0
PYH1_k127_7656941_0 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 400.0
PYH1_k127_7656941_1 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 294.0
PYH1_k127_7670688_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
PYH1_k127_7670688_1 Putative ATPase subunit of terminase (gpP-like) - - - 0.00000000005622 67.0
PYH1_k127_7672421_0 sptr a7nhu5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 482.0
PYH1_k127_7672421_1 Belongs to the 'phage' integrase family - - - 0.00000000000000005068 83.0
PYH1_k127_767315_0 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 410.0
PYH1_k127_767315_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 350.0
PYH1_k127_767315_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 344.0
PYH1_k127_7678678_0 radical SAM domain protein - - - 0.0 1195.0
PYH1_k127_7678678_1 radical SAM domain protein - - - 0.0 1172.0
PYH1_k127_7678678_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 528.0
PYH1_k127_7678678_3 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 442.0
PYH1_k127_7678678_4 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 299.0
PYH1_k127_7678678_5 PFAM AIG2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001309 243.0
PYH1_k127_7678678_6 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000003901 217.0
PYH1_k127_7678678_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000002464 194.0
PYH1_k127_7678678_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000000000002829 130.0
PYH1_k127_7681956_0 - - - - 5.883e-197 621.0
PYH1_k127_7681956_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 554.0
PYH1_k127_7681956_2 xylulokinase activity K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000007239 203.0
PYH1_k127_7681956_3 - - - - 0.00000000000000000000001484 110.0
PYH1_k127_7683219_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000003472 159.0
PYH1_k127_7683219_2 Domain of unknown function (DUF4304) - - - 0.0000000000000000000000000000000000000007011 151.0
PYH1_k127_7683219_4 COG NOG29403 non supervised orthologous group - - - 0.000000000002954 72.0
PYH1_k127_7683219_5 - - - - 0.0002404 51.0
PYH1_k127_7688097_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000009416 78.0
PYH1_k127_768871_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1152.0
PYH1_k127_7689102_0 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000001049 193.0
PYH1_k127_7689102_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.0000000000000000000000000000000000000006344 155.0
PYH1_k127_7689102_2 positive regulation of acetylcholine metabolic process K06910 - - 0.0000000000000000000000000000000478 126.0
PYH1_k127_7689102_3 AMP binding - - - 0.00000000000004719 83.0
PYH1_k127_7689102_4 BON domain - - - 0.00000000006576 63.0
PYH1_k127_7696185_0 6-phosphogluconolactonase activity - - - 0.00000000000000000005113 108.0
PYH1_k127_7696185_1 Conserved repeat domain - - - 0.000000000000008912 91.0
PYH1_k127_7696185_2 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000462 89.0
PYH1_k127_7696185_3 domain, Protein K01729,K03561,K09942,K12287,K20276 - 4.2.2.3 0.00000000118 74.0
PYH1_k127_7696185_4 Peptidase family C25 - - - 0.000002366 53.0
PYH1_k127_7696185_5 Protein of unknown function (DUF1565) - - - 0.0002052 57.0
PYH1_k127_7703894_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.015e-231 722.0
PYH1_k127_7703894_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000007478 58.0
PYH1_k127_7709605_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 534.0
PYH1_k127_7709605_1 Proteasomal ATPase OB/ID domain K13527 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 479.0
PYH1_k127_7709605_2 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 417.0
PYH1_k127_7709605_3 Evidence 5 No homology to any previously reported sequences K02450,K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
PYH1_k127_7709605_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000004236 197.0
PYH1_k127_7709605_6 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000000000000000000006636 189.0
PYH1_k127_7716676_0 arylsulfatase A K01130 - 3.1.6.1 7.381e-261 807.0
PYH1_k127_7716676_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 519.0
PYH1_k127_7717145_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 357.0
PYH1_k127_7717145_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000005174 129.0
PYH1_k127_7729337_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 441.0
PYH1_k127_7729337_1 ThiS family K03154 - - 0.00000000000000000003022 92.0
PYH1_k127_7729337_2 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.000000000000000002529 88.0
PYH1_k127_7733904_0 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 421.0
PYH1_k127_7734423_0 iron dependent repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 492.0
PYH1_k127_7734423_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000001081 122.0
PYH1_k127_7735599_0 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 387.0
PYH1_k127_7735599_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 372.0
PYH1_k127_7738944_0 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 451.0
PYH1_k127_7738944_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000001694 185.0
PYH1_k127_7738944_2 Methyltransferase domain - - - 0.000000000000000000000000000006211 124.0
PYH1_k127_7742312_0 methyltransferase - - - 1.964e-276 855.0
PYH1_k127_7742312_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005634 252.0
PYH1_k127_7742312_3 protein homooligomerization - - - 0.000000000000000000000000000000000018 143.0
PYH1_k127_7742312_4 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000002568 129.0
PYH1_k127_7742312_5 Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000001079 126.0
PYH1_k127_7742312_6 addiction module antidote protein HigA K21498 - - 0.0000000000000000000002008 99.0
PYH1_k127_7742312_8 Sulfatase-modifying factor enzyme 1 - - - 0.0000002931 52.0
PYH1_k127_7742312_9 methyltransferase - - - 0.0000006868 51.0
PYH1_k127_7742475_0 transporter K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 490.0
PYH1_k127_7747445_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 9.458e-247 774.0
PYH1_k127_7747445_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000009394 169.0
PYH1_k127_7747445_4 Domain of unknown function (DUF3817) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000002994 105.0
PYH1_k127_7749289_0 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 362.0
PYH1_k127_7749289_1 His Kinase A (phosphoacceptor) domain K00694,K03406,K07315,K14986 - 2.4.1.12,2.7.13.3,3.1.3.3 0.00000000000000000000007634 107.0
PYH1_k127_7749289_2 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.0000000000000000004564 90.0
PYH1_k127_7751286_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 305.0
PYH1_k127_7754696_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 535.0
PYH1_k127_7754696_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 325.0
PYH1_k127_7754696_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 271.0
PYH1_k127_7754696_3 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000001854 234.0
PYH1_k127_7754696_4 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000006127 202.0
PYH1_k127_7755129_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 387.0
PYH1_k127_7755129_1 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000003577 64.0
PYH1_k127_7756821_0 Transposase K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001736 268.0
PYH1_k127_7766367_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1086.0
PYH1_k127_7766367_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 342.0
PYH1_k127_7766367_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000001302 191.0
PYH1_k127_7773928_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 513.0
PYH1_k127_7773928_1 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 460.0
PYH1_k127_7776687_0 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 537.0
PYH1_k127_7776687_1 Pfam Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000001136 225.0
PYH1_k127_7785765_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 355.0
PYH1_k127_7799121_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 567.0
PYH1_k127_7799121_1 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000000005265 173.0
PYH1_k127_7799121_2 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000005502 125.0
PYH1_k127_7807979_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
PYH1_k127_7807979_1 RNA recognition motif - - - 0.0000000000000000000000002855 108.0
PYH1_k127_7807979_2 Putative transcription regulator (DUF1323) K07483 - - 0.000000000000001036 78.0
PYH1_k127_7814189_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000598 106.0
PYH1_k127_7829950_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1022.0
PYH1_k127_7843693_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 520.0
PYH1_k127_7843693_1 alpha amylase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 446.0
PYH1_k127_7855887_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 481.0
PYH1_k127_7855887_1 belongs to the CobB CobQ family K13788 GO:0005575,GO:0005576 2.3.1.8 0.00000000001198 64.0
PYH1_k127_7862731_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 431.0
PYH1_k127_7862731_1 thiolester hydrolase activity K06889,K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
PYH1_k127_7862731_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
PYH1_k127_7862731_4 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.00000000000000000002038 90.0
PYH1_k127_7868847_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 383.0
PYH1_k127_7868847_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000001399 217.0
PYH1_k127_7868847_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000004475 69.0
PYH1_k127_7870067_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
PYH1_k127_7895093_0 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 426.0
PYH1_k127_7941413_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 600.0
PYH1_k127_7941413_1 methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 581.0
PYH1_k127_7941413_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 544.0
PYH1_k127_7941413_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000005353 223.0
PYH1_k127_7941413_4 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000203 151.0
PYH1_k127_7946679_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 4.346e-302 925.0
PYH1_k127_7946679_1 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.00000000000000000000002733 98.0
PYH1_k127_7983263_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 470.0
PYH1_k127_7986775_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003961 277.0
PYH1_k127_7988829_0 transposase and inactivated derivatives, IS30 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002817 277.0
PYH1_k127_7997829_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 600.0
PYH1_k127_7997829_1 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
PYH1_k127_7997829_10 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000224 138.0
PYH1_k127_7997829_11 conserved protein (DUF2132) K06867 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000001286 128.0
PYH1_k127_7997829_12 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000003801 113.0
PYH1_k127_7997829_13 toxin-antitoxin pair type II binding K19159 - - 0.0000000000000000000000000004881 116.0
PYH1_k127_7997829_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000165 117.0
PYH1_k127_7997829_15 - - - - 0.00000000000000000000000001016 109.0
PYH1_k127_7997829_16 - - - - 0.000000000000000000000000971 108.0
PYH1_k127_7997829_17 - - - - 0.000000000000000000000004361 103.0
PYH1_k127_7997829_19 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000001421 87.0
PYH1_k127_7997829_2 glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 411.0
PYH1_k127_7997829_20 - - - - 0.00000000000000004841 87.0
PYH1_k127_7997829_22 Transposase IS200 like K07491 - - 0.00005518 49.0
PYH1_k127_7997829_3 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
PYH1_k127_7997829_4 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003175 266.0
PYH1_k127_7997829_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001532 259.0
PYH1_k127_7997829_6 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
PYH1_k127_7997829_7 endonuclease activity K03465 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.1.1.148 0.00000000000000000000000000000000000000000000000000000008691 196.0
PYH1_k127_7997829_8 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002417 181.0
PYH1_k127_7997829_9 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000006485 159.0
PYH1_k127_8013860_0 PhoQ Sensor - - - 9.717e-226 724.0
PYH1_k127_8013860_1 response regulator K02479,K07685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 313.0
PYH1_k127_8013860_2 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000338 240.0
PYH1_k127_8028374_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 343.0
PYH1_k127_8028374_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 259.0
PYH1_k127_8028469_1 - - - - 0.00003317 47.0
PYH1_k127_8048019_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000003528 187.0
PYH1_k127_8048019_1 - K09143 - - 0.0000000000001252 76.0
PYH1_k127_8048019_2 xylose isomerase-like TIM barrel - - - 0.000000001186 68.0
PYH1_k127_8048019_3 with the TIM-barrel fold - - - 0.00002868 47.0
PYH1_k127_8069216_0 GHKL domain K13598 - 2.7.13.3 0.0 1042.0
PYH1_k127_8072995_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1108.0
PYH1_k127_8072995_1 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 403.0
PYH1_k127_8072995_2 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001837 252.0
PYH1_k127_8078229_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 490.0
PYH1_k127_8078848_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 348.0
PYH1_k127_8078848_1 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000000000004826 213.0
PYH1_k127_8078848_2 Type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000005704 193.0
PYH1_k127_8078848_3 reverse transcriptase - - - 0.0000000001188 66.0
PYH1_k127_8078848_4 Recombinase - - - 0.0000000007552 59.0
PYH1_k127_8081716_0 - - - - 0.00000000000000000001278 98.0
PYH1_k127_8081716_1 Tetratricopeptide repeat - - - 0.0000000000003138 81.0
PYH1_k127_8087928_0 lipopolysaccharide transport K22110 - - 0.0 1466.0
PYH1_k127_8087928_1 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000005328 211.0
PYH1_k127_8087928_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.0000000000000000002893 91.0
PYH1_k127_8087928_3 - - - - 0.0000000007609 63.0
PYH1_k127_8087928_4 Sigma-54 interaction domain - - - 0.0000009448 51.0
PYH1_k127_8087928_5 PFAM nuclease (SNase domain protein) - - - 0.00003569 48.0
PYH1_k127_8087928_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0002677 46.0
PYH1_k127_809544_0 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 417.0
PYH1_k127_8128766_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000002911 126.0
PYH1_k127_8128766_1 Transposase - - - 0.000002393 58.0
PYH1_k127_8133970_0 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.000000000000000000000000000000000000000001616 156.0
PYH1_k127_8133970_2 DHH family K07462 - - 0.0000000000000000001223 90.0
PYH1_k127_8134846_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 319.0
PYH1_k127_8140592_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 359.0
PYH1_k127_8140592_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000006304 86.0
PYH1_k127_8173383_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000007362 233.0
PYH1_k127_8180964_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 8.223e-206 643.0
PYH1_k127_8182980_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 473.0
PYH1_k127_8182980_1 ubiE/COQ5 methyltransferase family - - - 0.00005403 47.0
PYH1_k127_8189163_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 314.0
PYH1_k127_8189163_1 - - - - 0.00000000001016 68.0
PYH1_k127_8195856_0 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 9.19e-220 691.0
PYH1_k127_8195856_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 554.0
PYH1_k127_8195856_2 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 284.0
PYH1_k127_8195856_4 Phage integrase family K04763 - - 0.000000002053 58.0
PYH1_k127_8203554_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 565.0
PYH1_k127_8213043_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 2.703e-199 623.0
PYH1_k127_8233580_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 383.0
PYH1_k127_8233580_1 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 360.0
PYH1_k127_8233580_2 Lysin motif - - - 0.000000000000000000000000000001013 125.0
PYH1_k127_8235132_0 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 451.0
PYH1_k127_8258633_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 565.0
PYH1_k127_8258633_1 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 469.0
PYH1_k127_8258633_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 419.0
PYH1_k127_8258633_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000000000000000001259 209.0
PYH1_k127_8258633_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000005662 119.0
PYH1_k127_8278625_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000002454 112.0
PYH1_k127_8278625_1 Acyltransferase family - - - 0.0002127 46.0
PYH1_k127_828942_0 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 320.0
PYH1_k127_828942_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 309.0
PYH1_k127_828942_2 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000009559 265.0
PYH1_k127_8318239_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 6.718e-215 678.0
PYH1_k127_8318239_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 435.0
PYH1_k127_8318239_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000005459 254.0
PYH1_k127_8318239_3 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000004183 129.0
PYH1_k127_83967_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 558.0
PYH1_k127_83967_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000002872 87.0
PYH1_k127_840171_0 amine dehydrogenase activity - - - 0.0 1358.0
PYH1_k127_840171_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000001918 85.0
PYH1_k127_840405_0 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 422.0
PYH1_k127_840405_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000001184 223.0
PYH1_k127_84623_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 479.0
PYH1_k127_84623_1 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 313.0
PYH1_k127_84623_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000009654 103.0
PYH1_k127_84623_3 GGDEF domain - - - 0.0000000342 56.0
PYH1_k127_855003_0 HTH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007872 267.0
PYH1_k127_855003_1 Dienelactone hydrolase - - - 0.0000000008921 71.0
PYH1_k127_855003_2 GYD domain - - - 0.00000004304 55.0
PYH1_k127_857810_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 6.916e-194 610.0
PYH1_k127_859282_0 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 374.0
PYH1_k127_859282_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 322.0
PYH1_k127_859282_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000002884 174.0
PYH1_k127_860582_0 ATPase activity K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 471.0
PYH1_k127_860582_1 peptidoglycan binding K03642 - - 0.00000000000000000000000000000000000000000000000001723 186.0
PYH1_k127_860582_2 - K01992 - - 0.000000000000000000000000000007873 120.0
PYH1_k127_861197_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 304.0
PYH1_k127_861197_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000006524 72.0
PYH1_k127_862195_0 Bacterial regulatory protein, Fis family K07715 - - 1.813e-206 649.0
PYH1_k127_862195_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 603.0
PYH1_k127_862195_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 364.0
PYH1_k127_862195_4 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001304 237.0
PYH1_k127_86368_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1013.0
PYH1_k127_86368_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 4.312e-298 924.0
PYH1_k127_86368_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 380.0
PYH1_k127_86368_11 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
PYH1_k127_86368_12 Cytochrome c K17052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 332.0
PYH1_k127_86368_13 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 315.0
PYH1_k127_86368_14 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
PYH1_k127_86368_16 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
PYH1_k127_86368_18 - - - - 0.0000000000000000000000000000000000000000000319 166.0
PYH1_k127_86368_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 5.711e-219 683.0
PYH1_k127_86368_3 Cytochrome b/b6/petB K00412 - - 1.566e-212 662.0
PYH1_k127_86368_4 Domain of unknown function (DUF3463) - - - 3.172e-206 644.0
PYH1_k127_86368_5 Evidence 5 No homology to any previously reported sequences K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 540.0
PYH1_k127_86368_6 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 489.0
PYH1_k127_86368_7 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 489.0
PYH1_k127_86368_8 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 419.0
PYH1_k127_86368_9 Cytochrome c K02305,K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 425.0
PYH1_k127_864898_0 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 340.0
PYH1_k127_864898_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000004767 221.0
PYH1_k127_865499_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.938e-308 953.0
PYH1_k127_866296_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 485.0
PYH1_k127_866296_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000003317 198.0
PYH1_k127_866296_2 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000000000000002649 176.0
PYH1_k127_86726_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002249 293.0
PYH1_k127_86726_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000004606 88.0
PYH1_k127_869523_0 transmembrane transport K02532,K05820,K08167,K08218,K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 474.0
PYH1_k127_869523_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 418.0
PYH1_k127_869523_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 336.0
PYH1_k127_869523_3 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 296.0
PYH1_k127_869523_4 response regulator, receiver K03413,K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 297.0
PYH1_k127_869523_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000001908 203.0
PYH1_k127_869523_9 - K14588 - - 0.0004795 46.0
PYH1_k127_870820_0 Sulfatase K01130 - 3.1.6.1 0.0 1310.0
PYH1_k127_870820_1 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000002986 82.0
PYH1_k127_875591_0 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000001409 250.0
PYH1_k127_875591_1 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.0000001157 62.0
PYH1_k127_877496_0 Pfam Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 369.0
PYH1_k127_877496_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 362.0
PYH1_k127_877496_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000003715 119.0
PYH1_k127_877496_3 converts alpha-aldose to the beta-anomer - - - 0.00000008262 57.0
PYH1_k127_879258_0 COG3666 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 409.0
PYH1_k127_881009_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 441.0
PYH1_k127_881009_1 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 352.0
PYH1_k127_881009_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000261 68.0
PYH1_k127_881653_0 helicase activity - - - 0.0 1283.0
PYH1_k127_881653_1 Uncharacterized protein family, UPF0114 K03535 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 296.0
PYH1_k127_881653_10 cheY-homologous receiver domain - - - 0.000000001312 64.0
PYH1_k127_881653_2 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002144 274.0
PYH1_k127_881653_3 Product type r regulator - - - 0.000000000000000000000000000000000000000000000000000000008345 205.0
PYH1_k127_881653_4 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001086 210.0
PYH1_k127_881653_5 - - - - 0.0000000000000000000000000000000000000000000000000003371 199.0
PYH1_k127_881653_6 Autoinducer binding domain - - - 0.000000000000000000000000000000004367 139.0
PYH1_k127_881653_7 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000007911 121.0
PYH1_k127_881653_8 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.00000000000000000000006863 108.0
PYH1_k127_881653_9 Acyl-homoserine-lactone synthase K13060,K13061,K18096,K20248,K20249,K20250 - 2.3.1.184,2.3.1.228,2.3.1.229 0.000000000000000000001329 104.0
PYH1_k127_883578_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 518.0
PYH1_k127_883578_1 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000000000003663 167.0
PYH1_k127_887615_0 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 9.847e-214 671.0
PYH1_k127_887615_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 335.0
PYH1_k127_887615_2 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 282.0
PYH1_k127_887615_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005462 265.0
PYH1_k127_887615_5 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000003019 67.0
PYH1_k127_887615_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00003024 47.0
PYH1_k127_89452_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1067.0
PYH1_k127_89452_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 381.0
PYH1_k127_89452_2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 309.0
PYH1_k127_89452_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 276.0
PYH1_k127_89452_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000033 222.0
PYH1_k127_89452_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.000000000000000000000000000000000000000000000000009655 185.0
PYH1_k127_89452_7 - - - - 0.00000000001468 68.0
PYH1_k127_89452_8 - - - - 0.0000000001607 66.0
PYH1_k127_895918_0 RNA recognition motif - - - 0.000000000000000000000000000000000000000000004313 166.0
PYH1_k127_897517_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 529.0
PYH1_k127_897517_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
PYH1_k127_897719_0 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 549.0
PYH1_k127_897719_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 353.0
PYH1_k127_897719_2 sirohydrochlorin cobaltochelatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 297.0
PYH1_k127_897719_3 - - - - 0.000000000000000000000000000000000000000000000000001156 184.0
PYH1_k127_897719_4 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.0000000000000000000000000000000008783 130.0
PYH1_k127_89885_0 transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 531.0
PYH1_k127_900086_0 Pectinacetylesterase - - - 0.0000000000000000000000000000000004081 140.0
PYH1_k127_9007_0 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 512.0
PYH1_k127_9007_1 Phage integrase family - - - 0.000000006172 61.0
PYH1_k127_901850_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 306.0
PYH1_k127_901850_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001013 254.0
PYH1_k127_901850_2 HicB family K18843 - - 0.0000000000000000000000000000000000003235 143.0
PYH1_k127_901850_3 GYD domain - - - 0.000000000000000000000000000002156 123.0
PYH1_k127_901850_4 transposition - - - 0.00000000000000139 81.0
PYH1_k127_901850_6 Stage II sporulation protein M K06384 - - 0.00000000000005711 74.0
PYH1_k127_902276_0 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000003298 123.0
PYH1_k127_902276_1 Glycosyl transferases group 1 K20444 - - 0.000000000000006422 85.0
PYH1_k127_90476_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000004703 166.0
PYH1_k127_90476_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000009142 90.0
PYH1_k127_90476_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000005283 81.0
PYH1_k127_916616_0 transferase activity, transferring hexosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 416.0
PYH1_k127_916616_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000954 149.0
PYH1_k127_916616_3 peptidyl-tyrosine sulfation - - - 0.000005069 48.0
PYH1_k127_921354_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 432.0
PYH1_k127_921354_2 amino acid - - - 0.00000000000000000001407 91.0
PYH1_k127_928076_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 8.004e-239 744.0
PYH1_k127_928076_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 355.0
PYH1_k127_928076_2 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.00000000000000000000000000000000000000000000005947 172.0
PYH1_k127_928076_3 spermidine synthase activity K00797 - 2.5.1.16 0.0000000000000000000000071 106.0
PYH1_k127_929269_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.089e-199 626.0
PYH1_k127_929269_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 570.0
PYH1_k127_929269_2 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 448.0
PYH1_k127_929916_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 437.0
PYH1_k127_929916_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000003257 234.0
PYH1_k127_929916_3 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000000000000000000000004691 104.0
PYH1_k127_929916_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08314 - 2.2.1.2 0.000000005344 57.0
PYH1_k127_936423_0 denitrification pathway - - - 6.646e-228 715.0
PYH1_k127_936423_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 535.0
PYH1_k127_936423_2 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 473.0
PYH1_k127_936423_3 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 407.0
PYH1_k127_936423_4 metalloendopeptidase activity K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 393.0
PYH1_k127_936423_5 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 313.0
PYH1_k127_936423_6 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000005384 177.0
PYH1_k127_936423_8 Small metal-binding protein - - - 0.000000000000000002261 89.0
PYH1_k127_939513_0 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 469.0
PYH1_k127_939513_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 448.0
PYH1_k127_939513_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 280.0
PYH1_k127_939513_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000002176 132.0
PYH1_k127_939513_4 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000001126 83.0
PYH1_k127_939513_5 - - - - 0.0002425 44.0
PYH1_k127_941768_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 429.0
PYH1_k127_941768_1 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000401 124.0
PYH1_k127_94726_0 Transposase DDE domain - - - 0.00000000000000000000676 106.0
PYH1_k127_94726_1 Zinc-dependent metalloprotease - - - 0.0000000000000000001147 90.0
PYH1_k127_94726_3 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 0.00002366 51.0
PYH1_k127_94726_4 Glycosyltransferase family 87 - - - 0.00005332 45.0
PYH1_k127_950551_0 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 265.0
PYH1_k127_953645_0 undecaprenyl-phosphate glucose phosphotransferase activity K15915,K19428 GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 282.0
PYH1_k127_953645_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000003568 226.0
PYH1_k127_953645_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000002213 162.0
PYH1_k127_953645_3 - - - - 0.00000000000000000000003934 102.0
PYH1_k127_961967_0 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 502.0
PYH1_k127_961967_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000002614 240.0
PYH1_k127_961967_2 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000002024 143.0
PYH1_k127_961967_4 - - - - 0.0000000000000000383 85.0
PYH1_k127_964137_0 AAA domain - - - 0.000000000000000000000000000000000000000000000001248 184.0
PYH1_k127_964137_1 Mu transposase, C-terminal - - - 0.00000000000000002249 88.0
PYH1_k127_968939_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 481.0
PYH1_k127_969068_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD HgdB - - - 0.000000000000000000000000000000000000000002688 168.0
PYH1_k127_969068_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000002064 63.0
PYH1_k127_969846_0 - - - - 0.000000000000000000000769 100.0
PYH1_k127_969846_1 - - - - 0.00000000000000001548 86.0
PYH1_k127_969846_2 ORF located using Blastx - - - 0.000000000002566 67.0
PYH1_k127_970126_0 Transposase DDE domain - - - 1.114e-223 707.0
PYH1_k127_975545_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 389.0
PYH1_k127_975545_1 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000018 65.0
PYH1_k127_976068_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000005254 262.0
PYH1_k127_979662_0 LAGLIDADG endonuclease - - - 0.000000000000000000000000000000000000000000000000000003655 197.0
PYH1_k127_979662_1 the current gene model (or a revised gene model) may contain a premature stop - - - 0.000000000000000000000000000000000002482 138.0
PYH1_k127_979662_2 non supervised orthologous group - - - 0.00000000000000000000000001063 122.0
PYH1_k127_979662_4 - - - - 0.000000001225 62.0
PYH1_k127_979662_5 COG NOG15344 non supervised orthologous group - - - 0.00000002672 55.0
PYH1_k127_997023_0 arylsulfatase A K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 539.0
PYH1_k127_997023_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 308.0
PYH1_k127_997023_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000001772 182.0