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Overview

ID MAG03158
Name PYH1_bin.54
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus Sulfuricurvum
Species
Assembly information
Completeness (%) 84.79
Contamination (%) 2.12
GC content (%) 45.0
N50 (bp) 9,618
Genome size (bp) 1,701,907

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1793

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1039997_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1289.0
PYH1_k127_1039997_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.858e-276 851.0
PYH1_k127_1039997_10 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000001949 203.0
PYH1_k127_1039997_11 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000000000000002018 180.0
PYH1_k127_1039997_12 Protein of unknown function (DUF2393) - - - 0.00000000000000000000000000000000000000000000000009673 182.0
PYH1_k127_1039997_13 Protein of unknown function (DUF2393) - - - 0.00000000000004046 79.0
PYH1_k127_1039997_14 Short-chain dehydrogenase reductase sdr - - - 0.000000000005718 66.0
PYH1_k127_1039997_2 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 590.0
PYH1_k127_1039997_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 587.0
PYH1_k127_1039997_4 Radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 556.0
PYH1_k127_1039997_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 546.0
PYH1_k127_1039997_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 472.0
PYH1_k127_1039997_7 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 417.0
PYH1_k127_1039997_8 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 383.0
PYH1_k127_1039997_9 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001615 276.0
PYH1_k127_1047441_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 6.579e-316 974.0
PYH1_k127_1047441_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.873e-276 852.0
PYH1_k127_1047441_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
PYH1_k127_1047441_11 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000002363 138.0
PYH1_k127_1047441_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 465.0
PYH1_k127_1047441_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 439.0
PYH1_k127_1047441_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 387.0
PYH1_k127_1047441_5 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 379.0
PYH1_k127_1047441_6 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 353.0
PYH1_k127_1047441_7 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
PYH1_k127_1047441_8 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 251.0
PYH1_k127_1047441_9 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001173 244.0
PYH1_k127_1078352_0 cAMP phosphodiesterases class-II - - - 4.136e-225 721.0
PYH1_k127_1078352_1 Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000002353 231.0
PYH1_k127_1078352_2 - - - - 0.00000000000000000000000000000000001426 143.0
PYH1_k127_1144526_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K17050 - - 0.0 1857.0
PYH1_k127_1144526_1 4Fe-4S dicluster domain K17051 - - 4.298e-241 745.0
PYH1_k127_1144526_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 3.953e-197 621.0
PYH1_k127_1144526_3 Cytochrome c-552 DMSO reductase-like, heme-binding domain K17052 - - 7.366e-196 616.0
PYH1_k127_1144526_4 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 327.0
PYH1_k127_1144526_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002411 265.0
PYH1_k127_1144526_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
PYH1_k127_1174382_0 HAMP domain - - - 2.92e-314 973.0
PYH1_k127_1174382_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 541.0
PYH1_k127_1174382_2 Arginosuccinate synthase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 530.0
PYH1_k127_1174382_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
PYH1_k127_1174382_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 234.0
PYH1_k127_1174382_5 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001973 231.0
PYH1_k127_1174382_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000001062 136.0
PYH1_k127_1174382_7 - - - - 0.0000000000000000000000000000000001147 136.0
PYH1_k127_1174382_9 P-type atpase K17686 - 3.6.3.54 0.00000007109 57.0
PYH1_k127_1179555_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 1.373e-205 647.0
PYH1_k127_1179555_1 chemotaxis protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 513.0
PYH1_k127_1179555_2 chemotaxis protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 282.0
PYH1_k127_1179555_3 - - - - 0.00000000000000000000000000000000000000000000000000001674 190.0
PYH1_k127_119113_0 ABC transporter, ATP-binding protein K15738 - - 0.0 1111.0
PYH1_k127_119113_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.426e-271 839.0
PYH1_k127_119113_11 Stress responsive A B Barrel Domain - - - 0.000000000000000000000000000000000000002075 148.0
PYH1_k127_119113_2 potassium channel protein K10716 - - 3.418e-203 644.0
PYH1_k127_119113_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 503.0
PYH1_k127_119113_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 413.0
PYH1_k127_119113_5 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001868 265.0
PYH1_k127_119113_6 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
PYH1_k127_119113_7 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000007122 205.0
PYH1_k127_119113_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000001479 178.0
PYH1_k127_1261913_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1545.0
PYH1_k127_1261913_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 2.973e-250 776.0
PYH1_k127_1261913_2 Ammonium Transporter K03320 - - 2.76e-231 721.0
PYH1_k127_1261913_3 Ammonium Transporter K03320 - - 9.056e-215 670.0
PYH1_k127_1261913_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 592.0
PYH1_k127_1261913_5 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000002955 212.0
PYH1_k127_1261913_6 (Lipo)protein K09860 - - 0.0000000000000000000000000000000000000000000000000000000000003311 214.0
PYH1_k127_1282160_0 twitching motility protein K02669 - - 5.143e-217 677.0
PYH1_k127_1282160_1 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 606.0
PYH1_k127_1282160_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 501.0
PYH1_k127_1282160_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000002045 64.0
PYH1_k127_1324794_0 Diguanylate cyclase - - - 1.142e-290 904.0
PYH1_k127_1324794_1 Putative diguanylate phosphodiesterase - - - 1.486e-247 780.0
PYH1_k127_1324794_2 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 362.0
PYH1_k127_1324794_3 oxidoreductase activity - - - 0.000000000308 73.0
PYH1_k127_136202_0 COG0642 Signal transduction histidine kinase - - - 2.411e-312 967.0
PYH1_k127_136202_1 Histidine kinase K20972 - - 2.979e-290 902.0
PYH1_k127_136202_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 369.0
PYH1_k127_136202_11 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 371.0
PYH1_k127_136202_12 flagellar motor K02557 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 359.0
PYH1_k127_136202_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 347.0
PYH1_k127_136202_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 310.0
PYH1_k127_136202_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 318.0
PYH1_k127_136202_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 303.0
PYH1_k127_136202_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
PYH1_k127_136202_18 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000373 235.0
PYH1_k127_136202_19 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000005734 181.0
PYH1_k127_136202_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.848e-239 747.0
PYH1_k127_136202_20 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000009798 163.0
PYH1_k127_136202_21 DNA-binding protein - - - 0.000000000000000000000000000000000001352 139.0
PYH1_k127_136202_22 - - - - 0.0000000000000000000005141 97.0
PYH1_k127_136202_23 Polysulphide reductase, NrfD - - - 0.00000000000000001106 83.0
PYH1_k127_136202_24 Cupin domain K11312 - - 0.00000000000000001497 85.0
PYH1_k127_136202_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 3.024e-237 737.0
PYH1_k127_136202_4 chemotaxis protein K03406 - - 1.19e-228 718.0
PYH1_k127_136202_5 fructose-bisphosphate aldolase K01624 - 4.1.2.13 2.931e-207 647.0
PYH1_k127_136202_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 565.0
PYH1_k127_136202_7 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 451.0
PYH1_k127_136202_8 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 438.0
PYH1_k127_136202_9 forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 429.0
PYH1_k127_1434830_0 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 4.786e-210 656.0
PYH1_k127_1434830_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 254.0
PYH1_k127_1434830_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000004577 64.0
PYH1_k127_14884_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1049.0
PYH1_k127_14884_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 604.0
PYH1_k127_14884_2 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000002128 193.0
PYH1_k127_1557751_0 Oligosaccharyl transferase, STT3 subunit K07151,K17251 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.99.18,2.4.99.19 2.147e-286 891.0
PYH1_k127_1557751_1 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 435.0
PYH1_k127_163276_0 DNA helicase K03657 - 3.6.4.12 0.0 1197.0
PYH1_k127_163276_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 531.0
PYH1_k127_163276_10 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.00000000000000000006787 89.0
PYH1_k127_163276_11 Global regulator protein family - - - 0.00001145 50.0
PYH1_k127_163276_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 445.0
PYH1_k127_163276_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 424.0
PYH1_k127_163276_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 415.0
PYH1_k127_163276_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000844 279.0
PYH1_k127_163276_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 273.0
PYH1_k127_163276_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000333 249.0
PYH1_k127_163276_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000000003873 149.0
PYH1_k127_163276_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000006669 130.0
PYH1_k127_1648415_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1270.0
PYH1_k127_1648415_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
PYH1_k127_1648415_2 NYN domain - - - 0.000000000000000000000000000000000000000000007141 163.0
PYH1_k127_1676832_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 4.408e-227 721.0
PYH1_k127_1676832_1 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 441.0
PYH1_k127_1676832_10 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000008758 48.0
PYH1_k127_1676832_2 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 336.0
PYH1_k127_1676832_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
PYH1_k127_1676832_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
PYH1_k127_1676832_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
PYH1_k127_1676832_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH1_k127_1676832_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
PYH1_k127_1676832_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
PYH1_k127_1679519_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 - 2.7.7.6 0.0 2821.0
PYH1_k127_1679519_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2072.0
PYH1_k127_1679519_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002882 81.0
PYH1_k127_1679519_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 424.0
PYH1_k127_1679519_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 340.0
PYH1_k127_1679519_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004976 273.0
PYH1_k127_1679519_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 272.0
PYH1_k127_1679519_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
PYH1_k127_1679519_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000000000005666 211.0
PYH1_k127_1679519_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000173 102.0
PYH1_k127_1679519_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000004427 91.0
PYH1_k127_1680823_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.15e-286 882.0
PYH1_k127_1680823_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.807e-226 702.0
PYH1_k127_1680823_10 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000001679 100.0
PYH1_k127_1680823_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 577.0
PYH1_k127_1680823_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 504.0
PYH1_k127_1680823_4 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 328.0
PYH1_k127_1680823_5 MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006012 267.0
PYH1_k127_1680823_6 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000005251 224.0
PYH1_k127_1680823_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000002657 198.0
PYH1_k127_1680823_8 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000001098 201.0
PYH1_k127_1680823_9 transport protein K03559 - - 0.000000000000000000000000000000000000000005133 157.0
PYH1_k127_1686837_0 Aminotransferase K14261 - - 4.365e-258 796.0
PYH1_k127_1686837_1 homoserine dehydrogenase K00003 - 1.1.1.3 8.371e-220 687.0
PYH1_k127_1686837_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000005039 77.0
PYH1_k127_1686837_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 602.0
PYH1_k127_1686837_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 391.0
PYH1_k127_1686837_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001983 250.0
PYH1_k127_1686837_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
PYH1_k127_1686837_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000002776 215.0
PYH1_k127_1686837_7 ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002383 209.0
PYH1_k127_1686837_8 - - - - 0.00000000000000000000000000000000000000000000000000007837 188.0
PYH1_k127_1686837_9 Nitrogen fixation protein NifU - - - 0.000000000000000000000000000000000000000000000001137 175.0
PYH1_k127_1699292_0 Two-component sensor histidine kinase response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 459.0
PYH1_k127_1704915_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1161.0
PYH1_k127_1704915_1 penicillin-binding protein K05515 - 3.4.16.4 5.215e-311 961.0
PYH1_k127_1704915_10 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
PYH1_k127_1704915_11 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
PYH1_k127_1704915_12 hmm pf01863 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
PYH1_k127_1704915_13 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
PYH1_k127_1704915_14 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000001803 227.0
PYH1_k127_1704915_15 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000003319 224.0
PYH1_k127_1704915_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000001115 207.0
PYH1_k127_1704915_17 - - - - 0.000000000000000000000000000000000000000000000000008941 184.0
PYH1_k127_1704915_18 - - - - 0.00000000000000000000000000000002034 131.0
PYH1_k127_1704915_19 - - - - 0.000000000000000003504 85.0
PYH1_k127_1704915_2 May be involved in recombinational repair of damaged DNA K03631 - - 3.25e-220 693.0
PYH1_k127_1704915_3 lytic murein transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 560.0
PYH1_k127_1704915_4 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 550.0
PYH1_k127_1704915_5 hydrolase, TatD K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 432.0
PYH1_k127_1704915_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 374.0
PYH1_k127_1704915_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 366.0
PYH1_k127_1704915_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 342.0
PYH1_k127_1704915_9 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 329.0
PYH1_k127_1711121_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.7e-322 989.0
PYH1_k127_1711121_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.091e-319 989.0
PYH1_k127_1711121_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.987e-265 822.0
PYH1_k127_1711121_3 Belongs to the GARS family K01945 - 6.3.4.13 4.615e-252 784.0
PYH1_k127_1711121_4 MlaD protein K02067 - - 6.127e-244 759.0
PYH1_k127_1711121_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.67e-205 642.0
PYH1_k127_1711121_6 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000001502 230.0
PYH1_k127_1711121_7 RDD family - - - 0.000000000000000000000000005808 115.0
PYH1_k127_1711121_8 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000003243 63.0
PYH1_k127_1718221_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 529.0
PYH1_k127_1718221_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 437.0
PYH1_k127_1718221_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 427.0
PYH1_k127_1718221_3 - - - - 0.0000000000000000000000000000000000000002095 159.0
PYH1_k127_1718221_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000001725 120.0
PYH1_k127_1718221_6 ABC transporter transmembrane region K06147,K11085 - - 0.0008562 43.0
PYH1_k127_1735928_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1997.0
PYH1_k127_1735928_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1257.0
PYH1_k127_1735928_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 474.0
PYH1_k127_1735928_11 dna polymerase iii K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 363.0
PYH1_k127_1735928_12 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 361.0
PYH1_k127_1735928_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 343.0
PYH1_k127_1735928_14 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 339.0
PYH1_k127_1735928_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
PYH1_k127_1735928_16 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 293.0
PYH1_k127_1735928_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001049 262.0
PYH1_k127_1735928_18 membrane - - - 0.0000000000000000000000000000000000000000000004327 168.0
PYH1_k127_1735928_19 L-threonylcarbamoyladenylate synthase - - - 0.000000000000000000000000000000000000000000001992 168.0
PYH1_k127_1735928_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 7.584e-318 983.0
PYH1_k127_1735928_20 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000002601 168.0
PYH1_k127_1735928_21 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.0000000000000000000000000000001181 123.0
PYH1_k127_1735928_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.204e-317 976.0
PYH1_k127_1735928_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.273e-237 737.0
PYH1_k127_1735928_5 Glutathionylspermidine synthase - - - 2.221e-223 696.0
PYH1_k127_1735928_6 outer membrane porin, OprD family - - - 6.081e-210 659.0
PYH1_k127_1735928_7 rod shape-determining protein mreB K03569 - - 2.043e-209 652.0
PYH1_k127_1735928_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 2.048e-194 611.0
PYH1_k127_1735928_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 526.0
PYH1_k127_1738099_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1474.0
PYH1_k127_1738099_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.742e-230 719.0
PYH1_k127_1738099_10 Peptidase A24 K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
PYH1_k127_1738099_11 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004156 278.0
PYH1_k127_1738099_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000002441 231.0
PYH1_k127_1738099_13 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
PYH1_k127_1738099_14 Diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000007969 206.0
PYH1_k127_1738099_15 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000001602 139.0
PYH1_k127_1738099_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 3.033e-217 679.0
PYH1_k127_1738099_3 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 545.0
PYH1_k127_1738099_4 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 505.0
PYH1_k127_1738099_5 Permease, YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 444.0
PYH1_k127_1738099_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 402.0
PYH1_k127_1738099_7 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 398.0
PYH1_k127_1738099_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 368.0
PYH1_k127_1738099_9 RecO N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 331.0
PYH1_k127_1761057_0 Two-component sensor histidine kinase response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 486.0
PYH1_k127_1761057_1 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 446.0
PYH1_k127_1761057_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 318.0
PYH1_k127_1761057_3 Belongs to the TtcA family K14058 - - 0.000000000000000000000001855 104.0
PYH1_k127_1771745_0 COG0842 ABC-type multidrug transport system, permease component K01992 - - 2.476e-200 629.0
PYH1_k127_1771745_1 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 533.0
PYH1_k127_1771745_10 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000002594 179.0
PYH1_k127_1771745_11 - - - - 0.000000000000000000001947 95.0
PYH1_k127_1771745_2 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 433.0
PYH1_k127_1771745_3 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
PYH1_k127_1771745_4 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 408.0
PYH1_k127_1771745_5 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 373.0
PYH1_k127_1771745_6 PFAM Polysaccharide deacetylase K14659,K22278 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
PYH1_k127_1771745_7 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 370.0
PYH1_k127_1771745_8 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 353.0
PYH1_k127_1771745_9 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 289.0
PYH1_k127_1788493_0 Flagellar basal body protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 435.0
PYH1_k127_1788493_1 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 307.0
PYH1_k127_1788493_2 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 282.0
PYH1_k127_179380_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 478.0
PYH1_k127_179380_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 324.0
PYH1_k127_179380_2 molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000001579 228.0
PYH1_k127_179380_3 molybdopterin converting factor K03636 - - 0.00000000000000000000000000000004652 125.0
PYH1_k127_1797582_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 594.0
PYH1_k127_1797582_1 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 409.0
PYH1_k127_1797582_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 403.0
PYH1_k127_1797582_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 315.0
PYH1_k127_1797582_4 GatB Yqey family protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000005475 222.0
PYH1_k127_1797582_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000001061 165.0
PYH1_k127_1797582_6 Cell division protein FtsX K09811 - - 0.00000000000000000000000000000000000005808 153.0
PYH1_k127_1846039_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 314.0
PYH1_k127_1846039_1 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000002624 218.0
PYH1_k127_1846039_2 HD domain - - - 0.0000000000000000000002275 107.0
PYH1_k127_1868474_0 TonB-dependent receptor - - - 2.287e-258 814.0
PYH1_k127_1868474_1 Belongs to the DEAD box helicase family - - - 2.291e-211 663.0
PYH1_k127_1868474_10 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
PYH1_k127_1868474_11 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000001093 254.0
PYH1_k127_1868474_12 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000001543 232.0
PYH1_k127_1868474_13 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000000000000000000000006576 219.0
PYH1_k127_1868474_14 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
PYH1_k127_1868474_15 - - - - 0.000000000000000000000000000005924 120.0
PYH1_k127_1868474_16 endonuclease containing a URI domain K07461 - - 0.00000000000000000000003599 101.0
PYH1_k127_1868474_17 His Kinase A (phosphoacceptor) domain - - - 0.0000355 51.0
PYH1_k127_1868474_2 EAL domain - - - 3.759e-197 621.0
PYH1_k127_1868474_3 Belongs to the SEDS family K05837 - - 4.322e-197 621.0
PYH1_k127_1868474_4 Fibronectin type 3 domain-containing protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 580.0
PYH1_k127_1868474_5 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 428.0
PYH1_k127_1868474_6 diguanylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 380.0
PYH1_k127_1868474_7 DNA RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 355.0
PYH1_k127_1868474_8 modulator of drug activity K03923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 331.0
PYH1_k127_1868474_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 305.0
PYH1_k127_1877195_0 arginine decarboxylase K01585 - 4.1.1.19 0.0 1166.0
PYH1_k127_1877195_1 COGs COG0069 Glutamate synthase domain 2 - - - 3.751e-238 749.0
PYH1_k127_1877195_2 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 424.0
PYH1_k127_1877195_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 295.0
PYH1_k127_1877195_4 LPP20 lipoprotein - - - 0.00000000000000000000000000000000000000000000004426 177.0
PYH1_k127_1877195_5 LPP20 lipoprotein - - - 0.00000000000000000000000000000000532 140.0
PYH1_k127_1877195_6 Transglutaminase-like - - - 0.00000000000000000000000001103 112.0
PYH1_k127_1877195_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000001409 64.0
PYH1_k127_192785_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.564e-303 935.0
PYH1_k127_192785_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 3.964e-241 750.0
PYH1_k127_192785_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 441.0
PYH1_k127_192785_3 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000004225 214.0
PYH1_k127_1964275_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1998.0
PYH1_k127_1964275_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1278.0
PYH1_k127_1964275_10 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000283 241.0
PYH1_k127_1964275_11 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000001189 229.0
PYH1_k127_1964275_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000009029 218.0
PYH1_k127_1964275_13 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000001412 213.0
PYH1_k127_1964275_14 HD domain K07814 - - 0.0000000000000000000426 94.0
PYH1_k127_1964275_15 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000002482 61.0
PYH1_k127_1964275_2 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 4.51e-216 672.0
PYH1_k127_1964275_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 564.0
PYH1_k127_1964275_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 531.0
PYH1_k127_1964275_5 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 529.0
PYH1_k127_1964275_6 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 370.0
PYH1_k127_1964275_7 Four helix bundle sensory module for signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 347.0
PYH1_k127_1964275_8 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 327.0
PYH1_k127_1964275_9 Ferritin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 284.0
PYH1_k127_1968288_0 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 443.0
PYH1_k127_1968288_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 438.0
PYH1_k127_1968288_2 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000002515 180.0
PYH1_k127_1968288_3 - - - - 0.000000000000000000000000003764 115.0
PYH1_k127_201633_0 ATP-dependent DNA helicase K03655 - 3.6.4.12 1.68e-293 910.0
PYH1_k127_201633_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 3.463e-213 663.0
PYH1_k127_201633_2 Peptidase, M16 - - - 1.554e-208 655.0
PYH1_k127_201633_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 482.0
PYH1_k127_201633_4 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 301.0
PYH1_k127_201633_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 288.0
PYH1_k127_201633_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006217 246.0
PYH1_k127_2076096_0 Type I secretion system ATPase K12541 - - 0.0 1151.0
PYH1_k127_2076096_1 Mur ligase middle domain K01929 - 6.3.2.10 3.099e-248 772.0
PYH1_k127_2076096_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000009623 99.0
PYH1_k127_2076096_11 Tetratricopeptide repeat - - - 0.000001487 57.0
PYH1_k127_2076096_12 COG1413 FOG HEAT repeat - - - 0.0002839 53.0
PYH1_k127_2076096_2 Outer membrane efflux protein K12543 - - 1.836e-236 739.0
PYH1_k127_2076096_3 HlyD membrane-fusion protein of T1SS K12542 - - 3.549e-229 715.0
PYH1_k127_2076096_4 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 561.0
PYH1_k127_2076096_5 HIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 280.0
PYH1_k127_2076096_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000107 241.0
PYH1_k127_2076096_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000002853 224.0
PYH1_k127_2076096_8 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000005735 170.0
PYH1_k127_2076096_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000009662 131.0
PYH1_k127_2095449_0 Belongs to the AAA ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 603.0
PYH1_k127_2095449_1 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 329.0
PYH1_k127_2095449_2 MiaB-like tRNA modifying enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 296.0
PYH1_k127_2105100_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.443e-288 889.0
PYH1_k127_2105100_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.772e-256 790.0
PYH1_k127_2105100_10 PDP protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005118 229.0
PYH1_k127_2105100_11 Flagellar FliJ protein - - - 0.000000000000000000000000000001237 126.0
PYH1_k127_2105100_12 cytochrome c oxidase K00407 - - 0.00000000000000000000000005675 108.0
PYH1_k127_2105100_2 Belongs to the CarA family K01956 - 6.3.5.5 1.793e-216 675.0
PYH1_k127_2105100_3 Aminotransferase - - - 2.873e-202 634.0
PYH1_k127_2105100_4 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 450.0
PYH1_k127_2105100_5 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 414.0
PYH1_k127_2105100_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 398.0
PYH1_k127_2105100_7 protein conserved in bacteria K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 297.0
PYH1_k127_2105100_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000008106 242.0
PYH1_k127_2105100_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000173 232.0
PYH1_k127_2165498_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.376e-282 870.0
PYH1_k127_2165498_1 Protein of unknown function (DUF3373) - - - 1.814e-237 743.0
PYH1_k127_2165498_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000001151 104.0
PYH1_k127_2165498_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 8.387e-197 617.0
PYH1_k127_2165498_3 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 493.0
PYH1_k127_2165498_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 461.0
PYH1_k127_2165498_5 Flagellar biosynthetic protein fliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 411.0
PYH1_k127_2165498_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 346.0
PYH1_k127_2165498_7 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
PYH1_k127_2165498_8 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 292.0
PYH1_k127_2165498_9 RESPONSE REGULATOR receiver K07288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001372 293.0
PYH1_k127_2264708_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1325.0
PYH1_k127_2264708_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 522.0
PYH1_k127_2264708_2 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 299.0
PYH1_k127_2264708_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000003796 162.0
PYH1_k127_2264708_4 AMMECR1 K09141 - - 0.0000001544 53.0
PYH1_k127_22695_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 589.0
PYH1_k127_22695_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 336.0
PYH1_k127_22695_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 300.0
PYH1_k127_22695_3 Mur ligase middle domain K01929 - 6.3.2.10 0.0000000000000000000005558 95.0
PYH1_k127_237588_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 521.0
PYH1_k127_237588_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 474.0
PYH1_k127_237588_2 Major facilitator superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
PYH1_k127_237588_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000001758 209.0
PYH1_k127_237588_4 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000000000000004468 204.0
PYH1_k127_2529152_0 Cytochrome c biogenesis protein - - - 0.0 1618.0
PYH1_k127_2529152_1 Putative glycosyl hydrolase domain - - - 3.203e-218 683.0
PYH1_k127_2529152_10 ABC transporter permease K02018 - - 0.00000000000000000000000000000002161 126.0
PYH1_k127_2529152_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.751e-214 668.0
PYH1_k127_2529152_3 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 7.565e-205 645.0
PYH1_k127_2529152_4 ATP-binding protein K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 436.0
PYH1_k127_2529152_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
PYH1_k127_2529152_6 protein-glutamate methylesterase activity K00575,K03412,K03413 - 2.1.1.80,3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 368.0
PYH1_k127_2529152_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 349.0
PYH1_k127_2529152_8 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000042 296.0
PYH1_k127_2529152_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000002274 227.0
PYH1_k127_2541945_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 3.113e-198 620.0
PYH1_k127_2541945_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 495.0
PYH1_k127_2541945_10 energy transducer activity K03832 - - 0.0000000000000000000000000000000000002485 149.0
PYH1_k127_2541945_11 Cytochrome c - - - 0.00000000000000000000000001189 113.0
PYH1_k127_2541945_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 478.0
PYH1_k127_2541945_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 449.0
PYH1_k127_2541945_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 341.0
PYH1_k127_2541945_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 312.0
PYH1_k127_2541945_6 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 278.0
PYH1_k127_2541945_7 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000001265 196.0
PYH1_k127_2541945_8 - - - - 0.0000000000000000000000000000000000000000000000000004545 185.0
PYH1_k127_2541945_9 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000001477 180.0
PYH1_k127_254842_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0 1073.0
PYH1_k127_2553946_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 7.357e-218 677.0
PYH1_k127_2553946_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 497.0
PYH1_k127_2553946_2 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006578 267.0
PYH1_k127_258847_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1431.0
PYH1_k127_258847_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.049e-250 777.0
PYH1_k127_258847_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 372.0
PYH1_k127_258847_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
PYH1_k127_258847_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000007468 211.0
PYH1_k127_258847_5 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000000000000000000000006865 194.0
PYH1_k127_258847_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000007693 63.0
PYH1_k127_26012_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 508.0
PYH1_k127_26012_1 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 462.0
PYH1_k127_26012_2 component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 451.0
PYH1_k127_26012_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
PYH1_k127_26012_4 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000006411 113.0
PYH1_k127_2642436_0 Oxidoreductase K00174 - 1.2.7.11,1.2.7.3 3.575e-196 616.0
PYH1_k127_2642436_1 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 515.0
PYH1_k127_2642436_2 oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 312.0
PYH1_k127_2642436_3 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000001388 188.0
PYH1_k127_2642436_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000001236 174.0
PYH1_k127_2642436_5 2-oxoglutarate acceptor oxidoreductase K00176 - 1.2.7.3 0.000000000000000000000000000000000000000000004704 164.0
PYH1_k127_2642436_6 Heavy-metal-associated domain - - - 0.000000000000000000000000000000001502 132.0
PYH1_k127_2642436_8 - - - - 0.0000004489 52.0
PYH1_k127_267765_0 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 439.0
PYH1_k127_267765_1 Signal transducing histidine kinase, homodimeric domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 404.0
PYH1_k127_267765_10 chemotaxis K03408 - - 0.00000000000000000003784 95.0
PYH1_k127_267765_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 363.0
PYH1_k127_267765_3 PFAM response regulator receiver K03407,K03413 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000005445 206.0
PYH1_k127_267765_4 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000007691 201.0
PYH1_k127_267765_5 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000003599 183.0
PYH1_k127_267765_6 HEAT repeats - - - 0.00000000000000000000000000000000000000000001274 163.0
PYH1_k127_267765_8 chemotaxis K03408 - - 0.00000000000000000000000000007331 121.0
PYH1_k127_2808258_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1195.0
PYH1_k127_2808258_1 Two-component sensor histidine kinase response regulator - - - 4.509e-208 677.0
PYH1_k127_2808258_10 Protein of unknown function (DUF3240) - - - 0.000000001742 62.0
PYH1_k127_2808258_2 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 451.0
PYH1_k127_2808258_3 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 388.0
PYH1_k127_2808258_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
PYH1_k127_2808258_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000004801 211.0
PYH1_k127_2808258_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000001421 193.0
PYH1_k127_2808258_7 Histidine kinase K07645 - 2.7.13.3 0.00000000000000000000000000000000000001504 160.0
PYH1_k127_2808258_8 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000001136 103.0
PYH1_k127_2808258_9 Outer membrane efflux protein K15725 - - 0.00000000000000000162 98.0
PYH1_k127_2914905_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1287.0
PYH1_k127_2914905_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 9.989e-253 785.0
PYH1_k127_2914905_10 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002663 266.0
PYH1_k127_2914905_11 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.0000000000000000000000000000000000000000000000000004413 185.0
PYH1_k127_2914905_12 Cytochrome c553 K08738 - - 0.000000000000000000000000000000000000000001202 158.0
PYH1_k127_2914905_13 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.000000000000000000000000000000000000000004646 160.0
PYH1_k127_2914905_14 Cytochrome oxidase maturation protein - - - 0.000000000000000000000000002904 111.0
PYH1_k127_2914905_2 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 3.065e-198 619.0
PYH1_k127_2914905_3 heptosyltransferase ii K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 575.0
PYH1_k127_2914905_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 563.0
PYH1_k127_2914905_5 lipopolysaccharide core region biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 539.0
PYH1_k127_2914905_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 418.0
PYH1_k127_2914905_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 358.0
PYH1_k127_2914905_8 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008349 278.0
PYH1_k127_2914905_9 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001607 266.0
PYH1_k127_3039907_0 Histidine kinase K03413,K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007677 271.0
PYH1_k127_3039907_1 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406,K05875 - - 0.00000000000000000000000000000000000000000000000000000000000000001315 227.0
PYH1_k127_322260_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1394.0
PYH1_k127_322260_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1204.0
PYH1_k127_322260_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0 1030.0
PYH1_k127_322260_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 5.484e-196 614.0
PYH1_k127_322260_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 400.0
PYH1_k127_322260_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 283.0
PYH1_k127_322260_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000007322 173.0
PYH1_k127_322260_7 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.000000000000001885 76.0
PYH1_k127_3388072_0 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 317.0
PYH1_k127_3388072_1 Histidine kinase A domain protein K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001005 277.0
PYH1_k127_3388072_2 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003096 246.0
PYH1_k127_3388072_3 Transcriptional regulator K15973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002864 240.0
PYH1_k127_3388072_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000002513 178.0
PYH1_k127_3440676_0 Thiol disulfide interchange protein K04084 - 1.8.1.8 9.771e-278 865.0
PYH1_k127_3440676_1 Pyridine nucleotide-disulphide oxidoreductase K17229 - 1.8.2.3 6.864e-271 838.0
PYH1_k127_3440676_10 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000000000000000000000001221 190.0
PYH1_k127_3440676_11 Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000003981 162.0
PYH1_k127_3440676_12 Sulfur oxidation protein SoxY - - - 0.0000000000000000000000000000000000009018 146.0
PYH1_k127_3440676_13 cytochrome c class I - - - 0.000000000000000000000000000000006981 134.0
PYH1_k127_3440676_14 Rhodanese Homology Domain - - - 0.00000000000000000174 84.0
PYH1_k127_3440676_15 superoxide reductase activity K05919,K17227 - 1.15.1.2 0.000000000000000004298 87.0
PYH1_k127_3440676_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 606.0
PYH1_k127_3440676_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 552.0
PYH1_k127_3440676_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 552.0
PYH1_k127_3440676_5 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 550.0
PYH1_k127_3440676_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 521.0
PYH1_k127_3440676_7 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 425.0
PYH1_k127_3440676_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
PYH1_k127_3440676_9 - - - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
PYH1_k127_3452478_0 STAS domain K03321 - - 0.0 1065.0
PYH1_k127_3452478_1 Highly conserved protein containing a thioredoxin domain K06888 - - 7.701e-294 914.0
PYH1_k127_3452478_2 threonine synthase K01733 - 4.2.3.1 2.11e-280 865.0
PYH1_k127_3452478_3 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 466.0
PYH1_k127_3452478_4 Helix-turn-helix domain K03892 - - 0.000000000000000000000000000000000000000000000000000000000000000000005626 235.0
PYH1_k127_3452478_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000001912 182.0
PYH1_k127_351914_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.534e-235 738.0
PYH1_k127_351914_1 COG4886 Leucine-rich repeat (LRR) protein - - - 1.096e-209 657.0
PYH1_k127_351914_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 310.0
PYH1_k127_351914_11 - - - - 0.0000000000000000000000000000000000000000000000000000000132 201.0
PYH1_k127_351914_12 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000000000000000000000000000001065 175.0
PYH1_k127_351914_13 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000412 166.0
PYH1_k127_351914_2 FAD binding domain K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 606.0
PYH1_k127_351914_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 514.0
PYH1_k127_351914_4 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 428.0
PYH1_k127_351914_5 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 412.0
PYH1_k127_351914_6 Abc transporter K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 393.0
PYH1_k127_351914_7 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 385.0
PYH1_k127_351914_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 360.0
PYH1_k127_351914_9 Methyltransferase domain K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 345.0
PYH1_k127_351974_0 growth of symbiont in host cell K07003 - - 3.338e-261 822.0
PYH1_k127_351974_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000003076 188.0
PYH1_k127_351974_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000002585 174.0
PYH1_k127_351974_3 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000003767 183.0
PYH1_k127_351974_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000001485 164.0
PYH1_k127_3523171_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1740.0
PYH1_k127_3523171_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.499e-288 887.0
PYH1_k127_3523171_10 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
PYH1_k127_3523171_11 Membrane K08984 - - 0.000000000000000000000000000000000000000000000000000006967 193.0
PYH1_k127_3523171_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000006085 99.0
PYH1_k127_3523171_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.148e-265 820.0
PYH1_k127_3523171_3 o-acetylhomoserine K01740 - 2.5.1.49 2.44e-239 743.0
PYH1_k127_3523171_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.338e-220 686.0
PYH1_k127_3523171_5 Belongs to the CinA family K03743 - 3.5.1.42 2.054e-194 612.0
PYH1_k127_3523171_6 hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 464.0
PYH1_k127_3523171_7 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 386.0
PYH1_k127_3523171_8 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 352.0
PYH1_k127_3523171_9 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 360.0
PYH1_k127_3524464_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1622.0
PYH1_k127_3524464_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.084e-296 912.0
PYH1_k127_3524464_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 304.0
PYH1_k127_3524464_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005802 252.0
PYH1_k127_3524464_12 peptidyl-prolyl K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000004251 228.0
PYH1_k127_3524464_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000002567 221.0
PYH1_k127_3524464_14 Belongs to the ATPase B chain family K02109 - - 0.000000000000000000000000000000000000000000000000000000000000006281 219.0
PYH1_k127_3524464_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000001344 213.0
PYH1_k127_3524464_16 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000002315 209.0
PYH1_k127_3524464_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000000000002968 191.0
PYH1_k127_3524464_18 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000001057 186.0
PYH1_k127_3524464_19 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000001094 165.0
PYH1_k127_3524464_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 4.828e-207 646.0
PYH1_k127_3524464_20 Protein of unknown function, DUF255 - - - 0.00000000000006467 77.0
PYH1_k127_3524464_3 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 489.0
PYH1_k127_3524464_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 475.0
PYH1_k127_3524464_5 RND efflux system, outer membrane lipoprotein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 469.0
PYH1_k127_3524464_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 449.0
PYH1_k127_3524464_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 441.0
PYH1_k127_3524464_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 428.0
PYH1_k127_3524464_9 HlyD family secretion protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 321.0
PYH1_k127_3541504_0 MgtC family - - - 8.803e-207 651.0
PYH1_k127_3541504_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 537.0
PYH1_k127_3541504_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 503.0
PYH1_k127_3541504_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 303.0
PYH1_k127_3541504_4 Uncharacterized conserved protein (DUF2249) - - - 0.000000000009657 66.0
PYH1_k127_357126_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 2.821e-226 704.0
PYH1_k127_357126_1 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 500.0
PYH1_k127_357126_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 447.0
PYH1_k127_357126_3 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 357.0
PYH1_k127_357126_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 329.0
PYH1_k127_357126_5 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000316 239.0
PYH1_k127_357126_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000003136 179.0
PYH1_k127_357126_7 Belongs to the MEMO1 family K06990 - - 0.000000000000000004606 86.0
PYH1_k127_3584499_0 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1104.0
PYH1_k127_3584499_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.224e-270 840.0
PYH1_k127_3584499_10 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 551.0
PYH1_k127_3584499_11 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 510.0
PYH1_k127_3584499_12 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 454.0
PYH1_k127_3584499_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 441.0
PYH1_k127_3584499_14 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 445.0
PYH1_k127_3584499_15 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 392.0
PYH1_k127_3584499_16 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 389.0
PYH1_k127_3584499_17 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 374.0
PYH1_k127_3584499_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 344.0
PYH1_k127_3584499_19 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 285.0
PYH1_k127_3584499_2 peptidase M23 - - - 3.177e-246 766.0
PYH1_k127_3584499_20 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002764 246.0
PYH1_k127_3584499_21 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000000001698 220.0
PYH1_k127_3584499_22 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000009612 198.0
PYH1_k127_3584499_23 oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000000000000108 187.0
PYH1_k127_3584499_24 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000005509 179.0
PYH1_k127_3584499_25 Ferredoxin K05337 - - 0.000000000000000000000000000000000000000000003047 164.0
PYH1_k127_3584499_26 COG1214 Inactive homolog of metal-dependent proteases - - - 0.000000000000000000000000000000000000000000007607 167.0
PYH1_k127_3584499_27 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000003239 134.0
PYH1_k127_3584499_28 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.0000000000000000000000000000001326 125.0
PYH1_k127_3584499_29 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000009026 49.0
PYH1_k127_3584499_3 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 2.475e-217 683.0
PYH1_k127_3584499_4 Histidine kinase K02484 - 2.7.13.3 4.187e-213 668.0
PYH1_k127_3584499_5 Receptor - - - 2.235e-211 667.0
PYH1_k127_3584499_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.768e-196 614.0
PYH1_k127_3584499_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 601.0
PYH1_k127_3584499_8 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 584.0
PYH1_k127_3584499_9 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 548.0
PYH1_k127_3595649_0 abc transporter atp-binding protein K06147,K06148 - - 3.795e-297 919.0
PYH1_k127_3595649_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.126e-224 709.0
PYH1_k127_3595649_2 Oxidoreductase K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 562.0
PYH1_k127_3595649_3 acid membrane antigen A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 488.0
PYH1_k127_3595649_4 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 446.0
PYH1_k127_3595649_5 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 387.0
PYH1_k127_3595649_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
PYH1_k127_3595649_7 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001768 193.0
PYH1_k127_3595649_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000001187 145.0
PYH1_k127_3595649_9 acid membrane antigen A - - - 0.00000000000000000000004356 104.0
PYH1_k127_3610799_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 593.0
PYH1_k127_3610799_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 364.0
PYH1_k127_3610799_2 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 297.0
PYH1_k127_3610799_3 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
PYH1_k127_3610799_4 biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000000000000000000006598 217.0
PYH1_k127_3610799_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000006556 176.0
PYH1_k127_3617865_0 AsmA-like C-terminal region - - - 3.413e-209 672.0
PYH1_k127_3617865_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.549e-198 623.0
PYH1_k127_3617865_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001486 276.0
PYH1_k127_3643570_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 563.0
PYH1_k127_3643570_1 Peptidase s1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 533.0
PYH1_k127_3643570_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 507.0
PYH1_k127_3643570_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 432.0
PYH1_k127_3643570_4 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000005185 190.0
PYH1_k127_3643570_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000176 115.0
PYH1_k127_3696726_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1317.0
PYH1_k127_3696726_1 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 1.192e-301 936.0
PYH1_k127_3696726_2 4Fe-4S dicluster domain K07307 - - 4.42e-285 881.0
PYH1_k127_3696726_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 574.0
PYH1_k127_3696726_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 348.0
PYH1_k127_3696726_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000457 202.0
PYH1_k127_3738473_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 532.0
PYH1_k127_3738473_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 434.0
PYH1_k127_3738473_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 366.0
PYH1_k127_3738473_3 ribosomal protein L3 K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 355.0
PYH1_k127_3738473_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
PYH1_k127_3738473_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000009069 199.0
PYH1_k127_3738473_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000000001263 191.0
PYH1_k127_3738473_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000003432 191.0
PYH1_k127_3738473_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000002543 176.0
PYH1_k127_3741636_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.074e-221 690.0
PYH1_k127_3741636_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 511.0
PYH1_k127_3741636_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
PYH1_k127_3741636_3 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000001041 141.0
PYH1_k127_3741636_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000904 77.0
PYH1_k127_3741636_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000184 48.0
PYH1_k127_3742114_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 507.0
PYH1_k127_3742114_1 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 304.0
PYH1_k127_3742114_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 303.0
PYH1_k127_3742114_3 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000002896 231.0
PYH1_k127_3742114_5 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000001118 92.0
PYH1_k127_3744408_0 Belongs to the heme-copper respiratory oxidase family - - - 1.665e-224 705.0
PYH1_k127_3744408_1 - - - - 1.208e-195 616.0
PYH1_k127_3744408_2 ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 536.0
PYH1_k127_3744408_5 - - - - 0.000000000000000000000000000000000000000000000000000000000374 208.0
PYH1_k127_3744408_6 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000001476 158.0
PYH1_k127_3830567_0 TonB dependent receptor K02014 - - 1.456e-312 970.0
PYH1_k127_3830567_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.588e-300 929.0
PYH1_k127_3830567_10 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02456 - - 0.000000000000000000000000000000000000001149 151.0
PYH1_k127_3830567_2 Glycolate oxidase subunit K00104 - 1.1.3.15 2.044e-279 861.0
PYH1_k127_3830567_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 1.031e-275 852.0
PYH1_k127_3830567_4 Competence protein K02238 - - 8.052e-211 662.0
PYH1_k127_3830567_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.111e-210 655.0
PYH1_k127_3830567_6 peptidase M23 - - - 6.381e-200 628.0
PYH1_k127_3830567_7 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 355.0
PYH1_k127_3830567_8 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000172 215.0
PYH1_k127_3830567_9 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000001106 204.0
PYH1_k127_38330_0 ABC transporter K11085 - - 1.287e-288 895.0
PYH1_k127_38330_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.078e-259 803.0
PYH1_k127_38330_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.649e-248 772.0
PYH1_k127_38330_3 Belongs to the peptidase M16 family - - - 9.455e-227 712.0
PYH1_k127_38330_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 2.021e-205 642.0
PYH1_k127_38330_5 Flagellar Assembly Protein A - - - 6.397e-205 651.0
PYH1_k127_38330_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 547.0
PYH1_k127_38330_7 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 528.0
PYH1_k127_38330_8 dehydrogenase K00076 - 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 500.0
PYH1_k127_38330_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 301.0
PYH1_k127_3842975_0 Histidine Phosphotransfer domain - - - 1.375e-199 652.0
PYH1_k127_3842975_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000005634 229.0
PYH1_k127_3842975_2 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000001573 107.0
PYH1_k127_4030410_0 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 459.0
PYH1_k127_4030410_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 390.0
PYH1_k127_4030410_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 357.0
PYH1_k127_4030410_3 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
PYH1_k127_4038201_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.86e-234 727.0
PYH1_k127_4038201_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 447.0
PYH1_k127_4038201_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 303.0
PYH1_k127_4038201_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 288.0
PYH1_k127_4038201_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001046 243.0
PYH1_k127_4038201_5 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000003082 221.0
PYH1_k127_4038201_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000002185 204.0
PYH1_k127_4038201_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000002127 126.0
PYH1_k127_4038201_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000003899 119.0
PYH1_k127_4038201_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000214 55.0
PYH1_k127_4211835_0 Putative diguanylate phosphodiesterase - - - 1.115e-259 819.0
PYH1_k127_4211835_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.446e-249 785.0
PYH1_k127_4211835_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000133 226.0
PYH1_k127_4233627_0 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 514.0
PYH1_k127_4233627_1 Belongs to the TtcA family K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 393.0
PYH1_k127_4233627_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 381.0
PYH1_k127_4233627_3 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 284.0
PYH1_k127_4302350_0 lytic murein transglycosylase K08309 - - 3.686e-280 868.0
PYH1_k127_4302350_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.29e-246 764.0
PYH1_k127_4302350_2 PFAM Type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 542.0
PYH1_k127_4302350_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 352.0
PYH1_k127_4302350_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 288.0
PYH1_k127_4302350_5 YGGT family K02221 - - 0.000000000000000000000000000000000000000002136 157.0
PYH1_k127_4302350_6 - - - - 0.000002413 56.0
PYH1_k127_4316669_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 2.864e-212 661.0
PYH1_k127_4316669_1 Alginate O-acetylation protein - - - 2.173e-207 655.0
PYH1_k127_4316669_10 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 363.0
PYH1_k127_4316669_11 PFAM O-Antigen K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 370.0
PYH1_k127_4316669_12 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
PYH1_k127_4316669_13 - - - - 0.000000000005378 77.0
PYH1_k127_4316669_14 protein conserved in bacteria K09824 - - 0.000002986 50.0
PYH1_k127_4316669_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 574.0
PYH1_k127_4316669_3 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 540.0
PYH1_k127_4316669_4 Glycosyl transferases group 1 K17249 - 2.4.1.292 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 531.0
PYH1_k127_4316669_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 497.0
PYH1_k127_4316669_6 involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 482.0
PYH1_k127_4316669_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 470.0
PYH1_k127_4316669_8 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 445.0
PYH1_k127_4316669_9 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 388.0
PYH1_k127_4337328_0 Heat shock 70 kDa protein K04043 - - 0.0 1142.0
PYH1_k127_4337328_1 abc transporter atp-binding protein - - - 0.0 1006.0
PYH1_k127_4337328_10 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 349.0
PYH1_k127_4337328_11 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 338.0
PYH1_k127_4337328_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 314.0
PYH1_k127_4337328_13 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
PYH1_k127_4337328_14 protein of Gammaproteobacteria UniRef RepID - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
PYH1_k127_4337328_15 ABC transporter, ATP-binding protein K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 290.0
PYH1_k127_4337328_17 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000001312 194.0
PYH1_k127_4337328_19 RNA-binding protein - - - 0.000000000000000000000000000000000000000000000001298 174.0
PYH1_k127_4337328_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 5.121e-235 732.0
PYH1_k127_4337328_20 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000006033 168.0
PYH1_k127_4337328_21 COG0471 Di- and tricarboxylate K03319 - - 0.00000000000000000000000000000000000000000611 156.0
PYH1_k127_4337328_22 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000002529 147.0
PYH1_k127_4337328_23 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000001481 125.0
PYH1_k127_4337328_24 S4 domain K14761 - - 0.0000000000000000000000005476 106.0
PYH1_k127_4337328_25 Protein of unknown function (DUF1653) - - - 0.0000000000000000000003444 97.0
PYH1_k127_4337328_26 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000001411 78.0
PYH1_k127_4337328_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 3.315e-228 710.0
PYH1_k127_4337328_4 Potassium uptake protein K03498 - - 2.177e-220 689.0
PYH1_k127_4337328_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 499.0
PYH1_k127_4337328_6 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
PYH1_k127_4337328_7 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 453.0
PYH1_k127_4337328_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 410.0
PYH1_k127_4337328_9 uptake protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 358.0
PYH1_k127_4371774_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1186.0
PYH1_k127_4371774_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1148.0
PYH1_k127_4371774_2 cobalamin-transporting ATPase activity K02014 - - 0.0 1086.0
PYH1_k127_4371774_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 9.447e-308 948.0
PYH1_k127_4371774_4 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 525.0
PYH1_k127_4371774_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 328.0
PYH1_k127_4371774_6 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 321.0
PYH1_k127_4371774_7 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 315.0
PYH1_k127_4371774_8 Abc transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 317.0
PYH1_k127_4371774_9 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002331 245.0
PYH1_k127_4383766_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1081.0
PYH1_k127_4383766_1 diguanylate cyclase - - - 0.0 1036.0
PYH1_k127_4383766_10 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 390.0
PYH1_k127_4383766_11 component of anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 350.0
PYH1_k127_4383766_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002403 273.0
PYH1_k127_4383766_13 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000002332 247.0
PYH1_k127_4383766_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.000000000000000000000000000000000000000000000000000000000088 206.0
PYH1_k127_4383766_15 response regulator - - - 0.00001194 56.0
PYH1_k127_4383766_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1011.0
PYH1_k127_4383766_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.653e-289 889.0
PYH1_k127_4383766_4 GGDEF domain - - - 3.712e-260 813.0
PYH1_k127_4383766_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 2.902e-231 718.0
PYH1_k127_4383766_6 sulfate adenylyltransferase K00958 - 2.7.7.4 9.874e-219 683.0
PYH1_k127_4383766_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.543e-210 653.0
PYH1_k127_4383766_8 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 583.0
PYH1_k127_4383766_9 4fe-4s ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 555.0
PYH1_k127_4387721_0 UDP-N-acetylglucosamine 4,6-dehydratase K15894 - 4.2.1.115 2.604e-201 628.0
PYH1_k127_4387721_1 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 592.0
PYH1_k127_4387721_2 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 449.0
PYH1_k127_4387721_3 CMP-N-acetylneuraminic acid synthetase K00983,K15899 - 2.7.7.43,2.7.7.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 414.0
PYH1_k127_4387721_4 pseudaminic acid biosynthesis-associated protein PseG K15897 - 3.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 319.0
PYH1_k127_4387721_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
PYH1_k127_4387721_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
PYH1_k127_4387721_7 - - - - 0.000000000000000000000000000000000008605 137.0
PYH1_k127_4387721_8 NeuB family K01654,K15898,K18430 - 2.5.1.101,2.5.1.56,2.5.1.97 0.0000000000006461 70.0
PYH1_k127_4390070_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 9.735e-212 659.0
PYH1_k127_4390070_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 1.121e-204 649.0
PYH1_k127_4390070_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000862 190.0
PYH1_k127_4390070_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001592 179.0
PYH1_k127_4407564_0 Major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 504.0
PYH1_k127_4407564_1 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 353.0
PYH1_k127_4407564_2 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 344.0
PYH1_k127_4407564_3 Flagellar hook protein flgE K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004665 246.0
PYH1_k127_4407564_4 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000001001 225.0
PYH1_k127_4407868_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0 1047.0
PYH1_k127_4407868_1 argininosuccinate lyase K01755 - 4.3.2.1 3.284e-265 820.0
PYH1_k127_4407868_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 520.0
PYH1_k127_4407868_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 417.0
PYH1_k127_4407868_4 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
PYH1_k127_4407868_5 - - - - 0.00000000000000000000000000000000000000000000009327 172.0
PYH1_k127_4407868_6 Hit family K02503 - - 0.0000000000000000000000000000000000000005419 148.0
PYH1_k127_4409251_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.768e-308 947.0
PYH1_k127_4409251_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03212,K03215 - 2.1.1.189,2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 537.0
PYH1_k127_4409251_2 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 497.0
PYH1_k127_4409251_3 metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 470.0
PYH1_k127_4409251_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 261.0
PYH1_k127_4409251_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000006689 229.0
PYH1_k127_4409251_6 endonuclease III K07457 - - 0.00000000000000000000000000000000000002581 146.0
PYH1_k127_4454470_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.083e-230 716.0
PYH1_k127_4454470_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 557.0
PYH1_k127_4454470_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002818 160.0
PYH1_k127_4454470_2 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 507.0
PYH1_k127_4454470_3 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 403.0
PYH1_k127_4454470_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 403.0
PYH1_k127_4454470_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 382.0
PYH1_k127_4454470_6 nucleoside-diphosphate sugar epimerase K07071 - - 0.0000000000000000000000000000000000000000000000007191 186.0
PYH1_k127_4454470_7 - - - - 0.00000000000000000000000000000000000000000000000366 174.0
PYH1_k127_4454470_8 - - - - 0.0000000000000000000000000000000000000000000000189 172.0
PYH1_k127_4454470_9 transport system auxiliary component K18480 - - 0.000000000000000000000000000000000000000000005048 171.0
PYH1_k127_451592_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1230.0
PYH1_k127_451592_1 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 593.0
PYH1_k127_451592_2 phosphorelay sensor kinase activity K01768,K07673,K07713 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 441.0
PYH1_k127_451592_3 - catabolite gene activator and regulatory subunit of cAMP-dependent protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 294.0
PYH1_k127_4616212_0 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 4.197e-266 827.0
PYH1_k127_4616212_1 COG2223 Nitrate nitrite transporter K02575 - - 5.722e-242 758.0
PYH1_k127_4616212_2 RNA binding S1 domain protein K06959 - - 1.866e-205 642.0
PYH1_k127_4616212_3 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 490.0
PYH1_k127_4616212_4 ABC transporter K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 452.0
PYH1_k127_4616212_5 Dtw domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 305.0
PYH1_k127_4616212_6 Outer membrane protein beta-barrel family K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 316.0
PYH1_k127_4616212_7 diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000143 185.0
PYH1_k127_4616212_8 diguanylate cyclase K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000008503 172.0
PYH1_k127_4616212_9 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000142 113.0
PYH1_k127_46794_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 475.0
PYH1_k127_46794_1 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000003597 206.0
PYH1_k127_46794_2 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000002024 103.0
PYH1_k127_4698939_0 K+ potassium transporter K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 330.0
PYH1_k127_4698939_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001387 256.0
PYH1_k127_4698939_2 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001624 247.0
PYH1_k127_4698939_4 - - - - 0.0000000000000000000000001704 106.0
PYH1_k127_4737714_1 - - - - 0.00000000000000000000000000000000000000000000000000000004204 201.0
PYH1_k127_4737714_2 Protein of unknown function (DUF3617) - - - 0.0000000000000000005994 89.0
PYH1_k127_4737714_3 - - - - 0.000000000000000001016 86.0
PYH1_k127_4936456_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 6.818e-266 827.0
PYH1_k127_4936456_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 5.202e-259 822.0
PYH1_k127_4936456_2 COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 2.724e-238 748.0
PYH1_k127_4936456_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 566.0
PYH1_k127_4936456_4 phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 459.0
PYH1_k127_4936456_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 334.0
PYH1_k127_4936456_6 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
PYH1_k127_4936456_7 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 291.0
PYH1_k127_4936456_8 alpha-ribazole phosphatase activity K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000152 173.0
PYH1_k127_4944619_0 glutamine synthetase K01915 - 6.3.1.2 9.89e-308 945.0
PYH1_k127_4944619_1 peptidase U32 family K08303 - - 4.118e-262 810.0
PYH1_k127_4944619_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 292.0
PYH1_k127_4944619_11 Histidine kinase K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001339 314.0
PYH1_k127_4944619_12 Protein of unknown function (DUF3972) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002111 246.0
PYH1_k127_4944619_13 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000001527 217.0
PYH1_k127_4944619_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 3.291e-259 801.0
PYH1_k127_4944619_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 591.0
PYH1_k127_4944619_4 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 505.0
PYH1_k127_4944619_5 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 423.0
PYH1_k127_4944619_6 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 409.0
PYH1_k127_4944619_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 371.0
PYH1_k127_4944619_8 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 329.0
PYH1_k127_4944619_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 312.0
PYH1_k127_4992_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1080.0
PYH1_k127_4992_1 flagellar motor switch protein K02410 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 555.0
PYH1_k127_4992_2 TIGRFAM urea ABC transporter, urea binding protein K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 371.0
PYH1_k127_4992_3 flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 324.0
PYH1_k127_4992_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 290.0
PYH1_k127_4992_5 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002481 246.0
PYH1_k127_4992_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000003259 208.0
PYH1_k127_4992_7 Histidine kinase K20974 - 2.7.13.3 0.00000000000000000000000000000000000000001941 165.0
PYH1_k127_4992_8 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000002099 130.0
PYH1_k127_5042315_0 anthranilate synthase component K01657 - 4.1.3.27 1.404e-207 650.0
PYH1_k127_5042315_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 387.0
PYH1_k127_5042315_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
PYH1_k127_5042315_3 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000001117 76.0
PYH1_k127_5048111_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1125.0
PYH1_k127_5048111_1 COG0457 FOG TPR repeat - - - 4.249e-315 982.0
PYH1_k127_5048111_2 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 524.0
PYH1_k127_5048111_3 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 481.0
PYH1_k127_5048111_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 441.0
PYH1_k127_5048111_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 361.0
PYH1_k127_5048111_6 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 301.0
PYH1_k127_5048111_7 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001389 245.0
PYH1_k127_5048111_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000005157 80.0
PYH1_k127_5048111_9 lipopolysaccharide heptosyltransferase K02841 - - 0.000000001774 59.0
PYH1_k127_5053379_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0 1067.0
PYH1_k127_5053379_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.849e-219 679.0
PYH1_k127_5053379_2 amine dehydrogenase activity K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 475.0
PYH1_k127_5053379_3 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 344.0
PYH1_k127_5053379_4 general secretion pathway protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 306.0
PYH1_k127_5053379_5 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000006799 237.0
PYH1_k127_5053379_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000001563 221.0
PYH1_k127_5053379_7 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000007593 205.0
PYH1_k127_5053379_8 Pilus assembly protein - - - 0.000000000000000000000000000000000000000000000000009866 183.0
PYH1_k127_5053379_9 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000002854 168.0
PYH1_k127_5070554_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 5.746e-200 631.0
PYH1_k127_5070554_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 539.0
PYH1_k127_5070554_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 498.0
PYH1_k127_5070554_3 -Amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 327.0
PYH1_k127_5070554_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 305.0
PYH1_k127_5073139_0 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 605.0
PYH1_k127_5073139_1 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000004432 201.0
PYH1_k127_5073139_2 Cold-shock protein K03704 - - 0.0000000000000000000000000000000000001618 141.0
PYH1_k127_5073139_3 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000000002547 111.0
PYH1_k127_5073139_4 - - - - 0.000000000000000000000001625 103.0
PYH1_k127_5073139_5 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000004474 85.0
PYH1_k127_5079355_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1356.0
PYH1_k127_5079355_1 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0 1015.0
PYH1_k127_5079355_10 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000000000000000006687 161.0
PYH1_k127_5079355_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000006281 122.0
PYH1_k127_5079355_12 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000006545 83.0
PYH1_k127_5079355_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 6.437e-213 670.0
PYH1_k127_5079355_3 Belongs to the SEDS family K03588 - - 1.373e-200 632.0
PYH1_k127_5079355_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 423.0
PYH1_k127_5079355_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 419.0
PYH1_k127_5079355_6 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 296.0
PYH1_k127_5079355_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 291.0
PYH1_k127_5079355_8 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
PYH1_k127_5115478_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1247.0
PYH1_k127_5115478_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1146.0
PYH1_k127_5115478_10 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 355.0
PYH1_k127_5115478_11 Nucleoside-specific channel-forming protein, Tsx - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 354.0
PYH1_k127_5115478_12 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 347.0
PYH1_k127_5115478_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 330.0
PYH1_k127_5115478_14 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 340.0
PYH1_k127_5115478_15 phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 322.0
PYH1_k127_5115478_16 PAS fold K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002431 239.0
PYH1_k127_5115478_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH1_k127_5115478_18 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000001041 119.0
PYH1_k127_5115478_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.148e-266 833.0
PYH1_k127_5115478_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.931e-211 659.0
PYH1_k127_5115478_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 588.0
PYH1_k127_5115478_5 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 495.0
PYH1_k127_5115478_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
PYH1_k127_5115478_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 452.0
PYH1_k127_5115478_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 377.0
PYH1_k127_5115478_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
PYH1_k127_5134312_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0 1041.0
PYH1_k127_5134312_1 Type II secretion system K02455,K12278 - - 1.848e-212 665.0
PYH1_k127_5134312_2 proteins homologs of microcin C7 resistance protein MccF - - - 0.000000000000000000000000000000000000000000000000000001181 196.0
PYH1_k127_5134312_3 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000009037 107.0
PYH1_k127_5134312_4 DNA helicase K03657 - 3.6.4.12 0.00000000002526 64.0
PYH1_k127_51379_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0 1135.0
PYH1_k127_51379_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 3.751e-206 643.0
PYH1_k127_51379_2 Hit family K02503 - - 0.000000000000000000000000000000000000000002427 157.0
PYH1_k127_51379_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000003238 84.0
PYH1_k127_5155089_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 9.551e-214 666.0
PYH1_k127_5155089_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 490.0
PYH1_k127_5155089_2 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 486.0
PYH1_k127_5155089_3 flagellar basal body K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 454.0
PYH1_k127_5155089_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 308.0
PYH1_k127_5155089_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001966 272.0
PYH1_k127_5155089_6 - - - - 0.000000000000000000000000000000006358 131.0
PYH1_k127_5155089_7 - - - - 0.00000000000000000003779 92.0
PYH1_k127_5155089_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000004218 84.0
PYH1_k127_5200308_0 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 3.139e-288 889.0
PYH1_k127_5200308_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.995e-277 856.0
PYH1_k127_5200308_2 Paralysed flagella protein - - - 7.385e-245 775.0
PYH1_k127_5258464_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.961e-306 942.0
PYH1_k127_5258464_1 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 526.0
PYH1_k127_5258464_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 355.0
PYH1_k127_5258464_3 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 350.0
PYH1_k127_5258464_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 343.0
PYH1_k127_5258464_5 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 313.0
PYH1_k127_5258464_6 Histidine kinase K03406,K05875,K07647 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007817 271.0
PYH1_k127_5260645_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.13e-249 775.0
PYH1_k127_5260645_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 5.026e-228 711.0
PYH1_k127_5260645_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.571e-211 658.0
PYH1_k127_5260645_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 567.0
PYH1_k127_5260645_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 505.0
PYH1_k127_5260645_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 349.0
PYH1_k127_5260645_6 - - - - 0.00000000000000000000000000000000000000000000000002917 182.0
PYH1_k127_5260645_7 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000005075 164.0
PYH1_k127_5260645_8 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000006124 157.0
PYH1_k127_5361185_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1341.0
PYH1_k127_5361185_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 390.0
PYH1_k127_5361185_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000366 159.0
PYH1_k127_5364784_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 2.071e-207 648.0
PYH1_k127_5364784_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 9.561e-198 619.0
PYH1_k127_5364784_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 429.0
PYH1_k127_5364784_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 336.0
PYH1_k127_5364784_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001227 263.0
PYH1_k127_5364784_5 Haem-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000456 246.0
PYH1_k127_5364784_6 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000000002544 157.0
PYH1_k127_5364784_7 Cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000009469 113.0
PYH1_k127_5364784_8 - - - - 0.0000000000000000002629 88.0
PYH1_k127_5371304_0 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 394.0
PYH1_k127_5371304_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 321.0
PYH1_k127_5371304_2 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000001592 193.0
PYH1_k127_5371304_3 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000003695 142.0
PYH1_k127_5377409_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 550.0
PYH1_k127_5377409_1 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 396.0
PYH1_k127_5377409_2 DnaJ domain protein K05801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 358.0
PYH1_k127_5377409_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008661 274.0
PYH1_k127_5377409_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008135 256.0
PYH1_k127_5377409_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000004587 111.0
PYH1_k127_5377409_6 Histidine kinase - - - 0.000000000000001261 79.0
PYH1_k127_5378390_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1255.0
PYH1_k127_5378390_1 Histidine kinase-like ATPases K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 575.0
PYH1_k127_5378390_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 489.0
PYH1_k127_5378390_3 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 387.0
PYH1_k127_5378390_4 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000000005109 171.0
PYH1_k127_5378390_5 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000001239 167.0
PYH1_k127_5378390_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0000000000000000000000000000000000000000002084 161.0
PYH1_k127_5378390_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000001212 156.0
PYH1_k127_5378390_8 PFAM DNA polymerase, beta domain protein region K07075 - - 0.0000000000401 68.0
PYH1_k127_5389095_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1403.0
PYH1_k127_5389095_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.16e-295 909.0
PYH1_k127_5389095_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.517e-272 846.0
PYH1_k127_5389095_3 apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 601.0
PYH1_k127_5389095_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 552.0
PYH1_k127_5389095_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 517.0
PYH1_k127_5389095_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 460.0
PYH1_k127_5389095_7 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000000000000000000006612 220.0
PYH1_k127_5389095_8 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
PYH1_k127_5389095_9 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000006154 98.0
PYH1_k127_5439774_0 Abc transporter K02035 - - 8.28e-271 839.0
PYH1_k127_5439774_1 COG1070 Sugar (pentulose and hexulose) K11216 - 2.7.1.189 7.279e-262 813.0
PYH1_k127_5439774_10 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000001156 184.0
PYH1_k127_5439774_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 2.714e-236 734.0
PYH1_k127_5439774_3 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 5.7e-201 626.0
PYH1_k127_5439774_4 carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 391.0
PYH1_k127_5439774_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 368.0
PYH1_k127_5439774_6 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 354.0
PYH1_k127_5439774_7 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004899 270.0
PYH1_k127_5439774_8 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
PYH1_k127_5439774_9 Sulfatase K03760 - 2.7.8.43 0.00000000000000000000000000000000000000000000000000000000000002447 216.0
PYH1_k127_5482949_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 600.0
PYH1_k127_5482949_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004729 262.0
PYH1_k127_5482949_2 - - - - 0.00000000005293 64.0
PYH1_k127_5482949_3 FecR protein - - - 0.0002055 51.0
PYH1_k127_5512156_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1178.0
PYH1_k127_5512156_1 Abc transporter K06158 - - 0.0 1077.0
PYH1_k127_5512156_2 phosphohydrolase (DHH superfamily) K07097 - - 1.279e-210 657.0
PYH1_k127_5512156_3 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 569.0
PYH1_k127_5512156_4 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000009271 244.0
PYH1_k127_5512156_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
PYH1_k127_5512156_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000003457 153.0
PYH1_k127_5512156_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000002131 149.0
PYH1_k127_5592053_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 6.618e-224 698.0
PYH1_k127_5592053_1 domain protein K09944 - - 3.844e-220 691.0
PYH1_k127_5592053_10 S4 domain protein - - - 0.00000000000000000000000000000000004278 135.0
PYH1_k127_5592053_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 591.0
PYH1_k127_5592053_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 539.0
PYH1_k127_5592053_4 ABC transporter, ATP-binding protein K01990,K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 438.0
PYH1_k127_5592053_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 422.0
PYH1_k127_5592053_6 tigr02757 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
PYH1_k127_5592053_7 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002359 247.0
PYH1_k127_5592053_8 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000000000000000000000000000000004989 224.0
PYH1_k127_5592053_9 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000164 138.0
PYH1_k127_5628955_0 acetolactate synthase K01652 - 2.2.1.6 0.0 1075.0
PYH1_k127_5628955_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 485.0
PYH1_k127_5628955_2 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 396.0
PYH1_k127_5628955_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 312.0
PYH1_k127_5628955_4 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008898 276.0
PYH1_k127_5628955_5 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000002588 202.0
PYH1_k127_5628955_6 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001784 188.0
PYH1_k127_5628955_7 - - - - 0.00000000000000000000000000000000002788 136.0
PYH1_k127_5666031_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1330.0
PYH1_k127_5666031_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 375.0
PYH1_k127_5666031_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004338 238.0
PYH1_k127_5666031_3 - - - - 0.00000000000000007657 83.0
PYH1_k127_5768738_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 9.901e-220 685.0
PYH1_k127_5768738_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.46e-215 673.0
PYH1_k127_5839610_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1011.0
PYH1_k127_5839610_1 Diguanylate cyclase with PAS PAC sensor - - - 1.855e-209 662.0
PYH1_k127_5839610_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002038 281.0
PYH1_k127_5839610_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000006466 155.0
PYH1_k127_5839610_4 Diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000008589 132.0
PYH1_k127_5839610_5 Four helix bundle sensory module for signal transduction - - - 0.00000000001137 65.0
PYH1_k127_5884434_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1334.0
PYH1_k127_5884434_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 606.0
PYH1_k127_5884434_2 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 507.0
PYH1_k127_5884434_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 432.0
PYH1_k127_5884434_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000137 227.0
PYH1_k127_5884434_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000001011 159.0
PYH1_k127_5885678_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 4.604e-207 644.0
PYH1_k127_5885678_1 DNA processing protein K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 376.0
PYH1_k127_5885678_2 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 364.0
PYH1_k127_5885678_3 cytochrome C oxidoreductase subunit B - - - 0.000000000000000000000000000000000000000000000000000003183 191.0
PYH1_k127_5885678_4 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 0.0000000000000000000000000000000000000000000000001226 177.0
PYH1_k127_5886467_0 Peptidase M48 K06013 - 3.4.24.84 3.167e-207 650.0
PYH1_k127_5886467_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 369.0
PYH1_k127_5886467_2 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 312.0
PYH1_k127_5886467_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000018 232.0
PYH1_k127_5892911_0 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 598.0
PYH1_k127_5892911_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 379.0
PYH1_k127_5892911_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 316.0
PYH1_k127_5894235_0 GAF domain K01768 - 4.6.1.1 0.0 1965.0
PYH1_k127_5894235_1 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.0 1107.0
PYH1_k127_5894235_10 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 490.0
PYH1_k127_5894235_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 488.0
PYH1_k127_5894235_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 434.0
PYH1_k127_5894235_13 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 402.0
PYH1_k127_5894235_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 357.0
PYH1_k127_5894235_15 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 352.0
PYH1_k127_5894235_16 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 344.0
PYH1_k127_5894235_17 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 337.0
PYH1_k127_5894235_18 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 304.0
PYH1_k127_5894235_19 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
PYH1_k127_5894235_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.367e-264 818.0
PYH1_k127_5894235_20 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005461 254.0
PYH1_k127_5894235_21 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008933 239.0
PYH1_k127_5894235_22 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
PYH1_k127_5894235_23 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
PYH1_k127_5894235_24 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000003129 195.0
PYH1_k127_5894235_25 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000007211 184.0
PYH1_k127_5894235_26 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000001382 181.0
PYH1_k127_5894235_27 - - - - 0.000000000000000000000000000000000000000002836 156.0
PYH1_k127_5894235_28 - - - - 0.000000000000000000000000000000000000000261 155.0
PYH1_k127_5894235_29 - - - - 0.000000000000000000000000000000001551 131.0
PYH1_k127_5894235_3 HD domain - - - 1.383e-253 789.0
PYH1_k127_5894235_32 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000000001989 102.0
PYH1_k127_5894235_33 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000002752 69.0
PYH1_k127_5894235_4 molybdopterin oxidoreductase - - - 3.753e-244 766.0
PYH1_k127_5894235_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 6.804e-224 697.0
PYH1_k127_5894235_6 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 612.0
PYH1_k127_5894235_7 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 574.0
PYH1_k127_5894235_8 Response regulator receiver K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 529.0
PYH1_k127_5894235_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 512.0
PYH1_k127_5914914_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.819e-219 685.0
PYH1_k127_5914914_1 TIGRFAM cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 293.0
PYH1_k127_5914914_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000001495 222.0
PYH1_k127_5914914_3 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000007763 216.0
PYH1_k127_5914914_4 phosphoribosyltransferase - - - 0.00000000000000000000000000003199 117.0
PYH1_k127_5925480_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.429e-232 722.0
PYH1_k127_5925480_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 531.0
PYH1_k127_5925480_2 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 476.0
PYH1_k127_5925480_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 378.0
PYH1_k127_5925480_4 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 277.0
PYH1_k127_5925480_5 - K12065 - - 0.0000000000000000000000000000000000000000000000000001066 199.0
PYH1_k127_5925480_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000000004848 136.0
PYH1_k127_5929463_0 PFAM dUTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 398.0
PYH1_k127_5929463_1 lipid a biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 395.0
PYH1_k127_5929463_2 lipopolysaccharide heptosyltransferase K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006002 269.0
PYH1_k127_5929463_3 - - - - 0.000000000002964 66.0
PYH1_k127_5933023_0 silver ion transport K07787,K15726 - - 6.242e-232 731.0
PYH1_k127_5933023_1 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004785 252.0
PYH1_k127_5933023_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.000000000005702 77.0
PYH1_k127_6003141_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.268e-263 820.0
PYH1_k127_6003141_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 1.353e-222 696.0
PYH1_k127_6003141_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000847 205.0
PYH1_k127_6003141_3 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.00000000000000000000000000000000000000000000000000000008114 196.0
PYH1_k127_6003141_4 Jag_N K06346 - - 0.000000000000000000000000000000000000000000000003071 183.0
PYH1_k127_6003141_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000000000001201 170.0
PYH1_k127_6003141_6 Belongs to the ClpA ClpB family K03694,K03695 - - 0.000000000000000000000001988 103.0
PYH1_k127_6003141_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000002516 100.0
PYH1_k127_6003141_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000002036 85.0
PYH1_k127_6005133_0 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 404.0
PYH1_k127_6005133_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 364.0
PYH1_k127_6005133_2 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 323.0
PYH1_k127_6005133_4 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000000000000000000000000000005628 128.0
PYH1_k127_6012259_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 604.0
PYH1_k127_6012259_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 561.0
PYH1_k127_6012259_2 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 283.0
PYH1_k127_6020521_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1156.0
PYH1_k127_6020521_1 Sigma factor PP2C-like phosphatases - - - 1.827e-296 915.0
PYH1_k127_6020521_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 448.0
PYH1_k127_6020521_11 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 443.0
PYH1_k127_6020521_12 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 391.0
PYH1_k127_6020521_13 response regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 387.0
PYH1_k127_6020521_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 317.0
PYH1_k127_6020521_15 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002982 267.0
PYH1_k127_6020521_16 protein conserved in bacteria K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000019 222.0
PYH1_k127_6020521_17 Domain of unknown function (DUF1987) - - - 0.00000000000000000000000000000000000000000000000000000000000007874 214.0
PYH1_k127_6020521_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000001346 196.0
PYH1_k127_6020521_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.175e-278 863.0
PYH1_k127_6020521_20 Cupin - - - 0.000000000000000000000000000000000000000000000000000003539 194.0
PYH1_k127_6020521_21 SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000003984 184.0
PYH1_k127_6020521_22 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000003192 95.0
PYH1_k127_6020521_23 Fe2 transport system protein A K04758 - - 0.000000000000009717 77.0
PYH1_k127_6020521_3 chemotaxis protein K03407 - 2.7.13.3 1.639e-278 866.0
PYH1_k127_6020521_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.748e-268 827.0
PYH1_k127_6020521_5 PFAM EAL domain - - - 2.184e-260 816.0
PYH1_k127_6020521_6 DNA recombination protein K09760 - - 2.319e-222 696.0
PYH1_k127_6020521_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 593.0
PYH1_k127_6020521_8 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 542.0
PYH1_k127_6020521_9 chemotaxis protein K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 517.0
PYH1_k127_6024868_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 6.32e-295 909.0
PYH1_k127_6024868_1 general secretion pathway protein K02247,K02456,K02679,K12285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003735 261.0
PYH1_k127_6024868_2 cell adhesion - - - 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
PYH1_k127_6024868_3 Prokaryotic N-terminal methylation motif K12285 - - 0.0000000000000000000000000000000000000000000000000000000701 199.0
PYH1_k127_6024868_4 cell adhesion - - - 0.000000000000000000000000000000000000000003846 161.0
PYH1_k127_6024868_5 cell adhesion - - - 0.0000000006944 63.0
PYH1_k127_6029213_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1454.0
PYH1_k127_6029213_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.455e-194 611.0
PYH1_k127_6029213_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 595.0
PYH1_k127_6029213_3 (EAL) domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 497.0
PYH1_k127_6029213_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 285.0
PYH1_k127_6029213_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000002666 101.0
PYH1_k127_6071442_0 Phosphoesterase family K01114 - 3.1.4.3 1.432e-219 688.0
PYH1_k127_6071442_1 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 422.0
PYH1_k127_6071442_10 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009278 273.0
PYH1_k127_6071442_11 Pfam Response regulator receiver K11443 - - 0.0000000000000000000000000000000000000000126 157.0
PYH1_k127_6071442_12 of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000000000000000000022 138.0
PYH1_k127_6071442_13 amino acid transport K02030,K10001 - - 0.00000000000000000000000000000000002112 145.0
PYH1_k127_6071442_14 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000004652 130.0
PYH1_k127_6071442_15 Rubredoxin - - - 0.000000000000000000004359 94.0
PYH1_k127_6071442_18 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000003332 64.0
PYH1_k127_6071442_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 428.0
PYH1_k127_6071442_3 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
PYH1_k127_6071442_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 373.0
PYH1_k127_6071442_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 370.0
PYH1_k127_6071442_6 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 318.0
PYH1_k127_6071442_7 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 287.0
PYH1_k127_6071442_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 301.0
PYH1_k127_6071442_9 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003126 299.0
PYH1_k127_6099355_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1129.0
PYH1_k127_6099355_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003355 261.0
PYH1_k127_6099355_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000003793 164.0
PYH1_k127_6099355_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000001662 60.0
PYH1_k127_610621_0 molybdopterin biosynthesis K03750 - 2.10.1.1 8.075e-211 661.0
PYH1_k127_610621_1 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 526.0
PYH1_k127_610621_2 molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000003272 119.0
PYH1_k127_6130991_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 292.0
PYH1_k127_6130991_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000000000000000002424 196.0
PYH1_k127_6130991_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000002383 173.0
PYH1_k127_6133707_0 Endoribonuclease that initiates mRNA decay K18682 - - 5.86e-246 768.0
PYH1_k127_6133707_1 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 546.0
PYH1_k127_6133707_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000001889 203.0
PYH1_k127_6133707_11 Cytochrome c family protein - - - 0.000000000000000000000000000000000000004335 152.0
PYH1_k127_6133707_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 539.0
PYH1_k127_6133707_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 442.0
PYH1_k127_6133707_4 hmm pf04305 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
PYH1_k127_6133707_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 332.0
PYH1_k127_6133707_6 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 287.0
PYH1_k127_6133707_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006116 263.0
PYH1_k127_6133707_8 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 226.0
PYH1_k127_6133707_9 thioesterase K02614 - - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
PYH1_k127_6153209_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.342e-262 809.0
PYH1_k127_6153209_1 TonB dependent receptor - - - 2.209e-246 779.0
PYH1_k127_6153209_2 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 492.0
PYH1_k127_6153209_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 417.0
PYH1_k127_6153209_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 336.0
PYH1_k127_6153209_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 303.0
PYH1_k127_6153209_6 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 303.0
PYH1_k127_6154420_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 368.0
PYH1_k127_6154420_1 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 331.0
PYH1_k127_6179839_0 flagellar biosynthesis K02404 - - 1.404e-241 751.0
PYH1_k127_6179839_1 Major facilitator superfamily K03762 - - 1.944e-199 629.0
PYH1_k127_6179839_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 301.0
PYH1_k127_6179839_11 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
PYH1_k127_6179839_12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000005352 229.0
PYH1_k127_6179839_13 - - - - 0.0000000000000000000000000000000000000000003157 159.0
PYH1_k127_6179839_14 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000009564 56.0
PYH1_k127_6179839_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 9.561e-198 619.0
PYH1_k127_6179839_3 flagellar motor switch protein K02416 - - 3.074e-195 612.0
PYH1_k127_6179839_4 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 496.0
PYH1_k127_6179839_5 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 472.0
PYH1_k127_6179839_6 flagellar motor switch protein K02417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 407.0
PYH1_k127_6179839_7 penicillin-binding protein K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 402.0
PYH1_k127_6179839_8 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 379.0
PYH1_k127_6179839_9 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 353.0
PYH1_k127_6194142_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1097.0
PYH1_k127_6194142_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.284e-293 905.0
PYH1_k127_6194142_2 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
PYH1_k127_6194142_3 Co-chaperone-curved DNA binding protein A K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
PYH1_k127_6194142_4 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 331.0
PYH1_k127_6194142_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 235.0
PYH1_k127_6194142_6 Transcriptional regulator K13640 - - 0.0000000000000000000000000000000000000000000000000000000000000002673 221.0
PYH1_k127_6194142_7 G T U mismatch-specific DNA glycosylase - - - 0.000000000000000000001962 94.0
PYH1_k127_6225139_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1022.0
PYH1_k127_6235221_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1758.0
PYH1_k127_6235221_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.69e-278 858.0
PYH1_k127_6235221_10 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 322.0
PYH1_k127_6235221_11 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 284.0
PYH1_k127_6235221_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000002346 258.0
PYH1_k127_6235221_13 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000326 237.0
PYH1_k127_6235221_14 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000000000000000000000000005167 197.0
PYH1_k127_6235221_15 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000003762 186.0
PYH1_k127_6235221_17 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 K10799 GO:0000209,GO:0000228,GO:0000242,GO:0000723,GO:0000781,GO:0000784,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0012505,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0016757,GO:0016763,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043412,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0045732,GO:0045862,GO:0045934,GO:0045935,GO:0046483,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051246,GO:0051247,GO:0051276,GO:0051641,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0071704,GO:0071840,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0098687,GO:1901360,GO:1901564,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001251,GO:2001252 2.4.2.30 0.00000000003437 74.0
PYH1_k127_6235221_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 6.208e-202 634.0
PYH1_k127_6235221_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 581.0
PYH1_k127_6235221_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 525.0
PYH1_k127_6235221_5 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 524.0
PYH1_k127_6235221_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 525.0
PYH1_k127_6235221_7 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 430.0
PYH1_k127_6235221_8 flagellar - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 396.0
PYH1_k127_6235221_9 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 340.0
PYH1_k127_6235499_0 Histidine kinase - - - 0.0 1129.0
PYH1_k127_6235499_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.017e-286 888.0
PYH1_k127_6235499_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 508.0
PYH1_k127_6235499_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
PYH1_k127_6235499_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000002355 205.0
PYH1_k127_6235965_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1137.0
PYH1_k127_6235965_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.953e-269 833.0
PYH1_k127_6235965_10 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 380.0
PYH1_k127_6235965_11 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 361.0
PYH1_k127_6235965_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 349.0
PYH1_k127_6235965_13 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 319.0
PYH1_k127_6235965_14 transformation system protein K02242 - - 0.000000000000000000000000000000000000000000000000000000000000004659 218.0
PYH1_k127_6235965_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001366 136.0
PYH1_k127_6235965_16 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000001871 118.0
PYH1_k127_6235965_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.202e-248 769.0
PYH1_k127_6235965_3 Chemotaxis phosphatase CheX - - - 2.113e-236 737.0
PYH1_k127_6235965_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 3.009e-222 693.0
PYH1_k127_6235965_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.548e-201 630.0
PYH1_k127_6235965_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 572.0
PYH1_k127_6235965_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 571.0
PYH1_k127_6235965_8 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 432.0
PYH1_k127_6235965_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 414.0
PYH1_k127_6262536_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 574.0
PYH1_k127_6262536_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 421.0
PYH1_k127_6262536_2 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
PYH1_k127_6262536_3 Belongs to the UPF0250 family - - - 0.000000000000001113 76.0
PYH1_k127_626797_0 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 460.0
PYH1_k127_626797_1 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 376.0
PYH1_k127_626797_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 290.0
PYH1_k127_626797_3 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000000000000002477 203.0
PYH1_k127_626797_4 beta-lactamase activity K01058,K07126,K12543 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000002187 195.0
PYH1_k127_626797_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000005731 154.0
PYH1_k127_632125_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1090.0
PYH1_k127_632125_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 1.475e-221 689.0
PYH1_k127_632125_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 367.0
PYH1_k127_632125_3 - - - - 0.000000000000000000000000000000000000000000000000003131 188.0
PYH1_k127_632125_4 flagellar basal body K02392 - - 0.00000000000000000000000000000000000000000001374 164.0
PYH1_k127_632125_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000007858 108.0
PYH1_k127_632125_6 COG0841 Cation multidrug efflux pump - - - 0.00000000000000000000003739 100.0
PYH1_k127_6332563_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.214e-265 821.0
PYH1_k127_6332563_1 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 332.0
PYH1_k127_6333599_0 Multicopper oxidase K22348 - 1.16.3.3 1.07e-268 829.0
PYH1_k127_6333599_1 Protein of unknown function (DUF3137) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 564.0
PYH1_k127_6333599_2 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 551.0
PYH1_k127_6333599_3 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 500.0
PYH1_k127_6333599_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 309.0
PYH1_k127_6333599_5 hmm pf01205 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
PYH1_k127_6333599_6 Outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000000000000000000000000001828 209.0
PYH1_k127_6333599_7 Membrane K08984 - - 0.000000000000000000000000000000000000000001632 158.0
PYH1_k127_6333599_8 Copper binding periplasmic protein CusF K07810 - - 0.000000000000000000000000000000000005563 139.0
PYH1_k127_6335866_0 DNA helicase K03657 - 3.6.4.12 0.0 1258.0
PYH1_k127_6335866_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.947e-267 824.0
PYH1_k127_6335866_2 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000000000000000000003951 183.0
PYH1_k127_6358080_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
PYH1_k127_6358080_1 G T U mismatch-specific DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001348 223.0
PYH1_k127_6358080_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000001805 106.0
PYH1_k127_6371580_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.728e-240 772.0
PYH1_k127_6371580_1 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 304.0
PYH1_k127_6371580_2 Helix-turn-helix domain - - - 0.000000000000000000000000001203 115.0
PYH1_k127_6371580_3 - - - - 0.0000002157 54.0
PYH1_k127_6371580_4 MORN repeat variant - - - 0.0000006305 55.0
PYH1_k127_6442042_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.199e-259 801.0
PYH1_k127_6442042_1 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 458.0
PYH1_k127_6442042_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000004412 196.0
PYH1_k127_6442042_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000005822 188.0
PYH1_k127_6443086_0 diguanylate cyclase - - - 9.395e-207 661.0
PYH1_k127_6443086_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 347.0
PYH1_k127_6443086_3 chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000000000000000000005882 221.0
PYH1_k127_6443086_4 2'-5' RNA ligase K01975 - 3.1.4.58 0.0000000000000000000000000000001495 126.0
PYH1_k127_6463112_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 1.048e-220 688.0
PYH1_k127_6463112_1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 553.0
PYH1_k127_6463112_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 370.0
PYH1_k127_6463112_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 307.0
PYH1_k127_6463112_4 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
PYH1_k127_6463112_5 Flagellar hook protein flgE - - - 0.0000000000000000000000000000001428 126.0
PYH1_k127_6509761_0 COG3893 inactivated superfamily I helicase - - - 6.532e-286 898.0
PYH1_k127_6509761_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 313.0
PYH1_k127_6509761_2 FixH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002713 256.0
PYH1_k127_6509761_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 255.0
PYH1_k127_6509761_4 Family of unknown function (DUF4006) - - - 0.0000000000000002212 84.0
PYH1_k127_6509761_5 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.0000000000004449 68.0
PYH1_k127_6529456_0 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 611.0
PYH1_k127_6529456_1 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 558.0
PYH1_k127_6529456_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
PYH1_k127_6529456_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 284.0
PYH1_k127_6529456_4 Chaperone for flagella basal body P-ring formation K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 289.0
PYH1_k127_6529456_5 Thymidylate kinase K00943 - 2.7.4.9 0.00000000000000003678 88.0
PYH1_k127_6529456_6 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component - - - 0.0001172 44.0
PYH1_k127_65318_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 605.0
PYH1_k127_65318_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 519.0
PYH1_k127_65318_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 512.0
PYH1_k127_65318_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 333.0
PYH1_k127_65318_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
PYH1_k127_65318_5 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000005635 196.0
PYH1_k127_65318_7 - - - - 0.0000000000000000000000000000006281 122.0
PYH1_k127_65318_8 Prokaryotic metallothionein K06950 - - 0.000000000000000000001002 96.0
PYH1_k127_6673341_0 K+ potassium transporter K03549 - - 3.399e-234 731.0
PYH1_k127_6673341_1 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 8.852e-221 691.0
PYH1_k127_6673341_2 Cytochrome K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 550.0
PYH1_k127_6673341_3 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 371.0
PYH1_k127_6673341_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 304.0
PYH1_k127_6673341_5 COGs COG3786 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003723 266.0
PYH1_k127_6709099_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1171.0
PYH1_k127_6709099_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.4e-248 769.0
PYH1_k127_6709099_10 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 242.0
PYH1_k127_6709099_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000003 226.0
PYH1_k127_6709099_12 ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002383 209.0
PYH1_k127_6709099_13 Nitrogen fixation protein NifU - - - 0.0000000000000000000000000000000000000000000000006041 176.0
PYH1_k127_6709099_14 - - - - 0.000000000000000000000000000000000000000003437 162.0
PYH1_k127_6709099_15 Thioredoxin - - - 0.00000000000000000006786 95.0
PYH1_k127_6709099_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.513e-244 758.0
PYH1_k127_6709099_3 Sodium calcium exchanger membrane K07300 - - 4.484e-196 616.0
PYH1_k127_6709099_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 605.0
PYH1_k127_6709099_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 513.0
PYH1_k127_6709099_6 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 459.0
PYH1_k127_6709099_7 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 439.0
PYH1_k127_6709099_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 420.0
PYH1_k127_6709099_9 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 329.0
PYH1_k127_6709780_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 584.0
PYH1_k127_6709780_1 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
PYH1_k127_6710702_0 molybdopterin biosynthesis K03750 - 2.10.1.1 3.791e-207 650.0
PYH1_k127_6710702_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 451.0
PYH1_k127_6710702_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 402.0
PYH1_k127_6710702_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 315.0
PYH1_k127_6710702_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000003552 162.0
PYH1_k127_6710702_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000003794 129.0
PYH1_k127_6710702_7 Protein conserved in bacteria - - - 0.000000000003251 68.0
PYH1_k127_6713613_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1073.0
PYH1_k127_6713613_1 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 2.03e-251 789.0
PYH1_k127_6713613_10 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000009162 211.0
PYH1_k127_6713613_11 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000004603 120.0
PYH1_k127_6713613_12 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000001315 70.0
PYH1_k127_6713613_13 Belongs to the MEMO1 family K06990 - - 0.000000000009172 66.0
PYH1_k127_6713613_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 5.805e-248 767.0
PYH1_k127_6713613_3 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 563.0
PYH1_k127_6713613_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 507.0
PYH1_k127_6713613_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 431.0
PYH1_k127_6713613_6 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 320.0
PYH1_k127_6713613_7 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
PYH1_k127_6713613_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 258.0
PYH1_k127_6713613_9 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004796 258.0
PYH1_k127_6738208_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 2.151e-303 936.0
PYH1_k127_6738208_1 COG1450 Type II secretory pathway component PulD K02453 - - 3.916e-235 737.0
PYH1_k127_6738208_2 COG1459 Type II secretory pathway, component PulF K02455 - - 3.754e-211 661.0
PYH1_k127_6738208_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 496.0
PYH1_k127_6738208_4 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 361.0
PYH1_k127_6738208_6 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004494 236.0
PYH1_k127_6738208_8 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000003709 134.0
PYH1_k127_6744272_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
PYH1_k127_6744272_1 Superoxide dismutase K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
PYH1_k127_6744272_2 COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain) K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 287.0
PYH1_k127_6770102_0 Protein of unknown function (DUF2867) - - - 2.52e-218 685.0
PYH1_k127_6770102_1 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 331.0
PYH1_k127_6770102_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009488 270.0
PYH1_k127_6770102_3 Protein of unknown function (DUF3617) - - - 0.000000000000000009947 88.0
PYH1_k127_6776121_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.152e-260 805.0
PYH1_k127_6776121_1 na -driven multidrug efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 550.0
PYH1_k127_6776121_10 - - - - 0.0000000000000000000000000000000000004496 141.0
PYH1_k127_6776121_11 C-terminal domain of metallo-carboxypeptidase - - - 0.000000000000000000000001322 105.0
PYH1_k127_6776121_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 540.0
PYH1_k127_6776121_3 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 504.0
PYH1_k127_6776121_4 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 443.0
PYH1_k127_6776121_5 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 318.0
PYH1_k127_6776121_6 flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000000000000000000000000000004239 218.0
PYH1_k127_6776121_7 Belongs to the DNA mismatch repair MutS family K03555 - - 0.000000000000000000000000000000000000000000000000000000003816 210.0
PYH1_k127_6776121_8 FlaG protein K06603 - - 0.00000000000000000000000000000000000000000003432 164.0
PYH1_k127_6776121_9 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000003713 157.0
PYH1_k127_6778185_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 8.594e-259 800.0
PYH1_k127_6778185_1 TIGRFAM N-acetyl sugar amidotransferase - - - 1.186e-246 762.0
PYH1_k127_6778185_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related - - - 1.283e-226 708.0
PYH1_k127_6778185_3 hmm pf01973 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 595.0
PYH1_k127_6778185_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 508.0
PYH1_k127_6778185_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 481.0
PYH1_k127_6778185_6 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
PYH1_k127_6778185_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000109 274.0
PYH1_k127_6813615_0 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 6.442e-282 872.0
PYH1_k127_6813615_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.02e-239 740.0
PYH1_k127_6813615_10 - - - - 0.000000000000000000000000000009006 119.0
PYH1_k127_6813615_11 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000001976 99.0
PYH1_k127_6813615_12 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000001411 58.0
PYH1_k127_6813615_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 590.0
PYH1_k127_6813615_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 587.0
PYH1_k127_6813615_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 508.0
PYH1_k127_6813615_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001812 252.0
PYH1_k127_6813615_6 phosphoribosyltransferase K00769 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000006055 225.0
PYH1_k127_6813615_7 (HIT) family - - - 0.00000000000000000000000000000000000000000000000000000000005445 206.0
PYH1_k127_6813615_8 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000001189 198.0
PYH1_k127_6813615_9 metal-binding, possibly nucleic acid-binding protein - - - 0.000000000000000000000000000000000000000000003255 166.0
PYH1_k127_6842808_0 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 559.0
PYH1_k127_6842808_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 359.0
PYH1_k127_6880854_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 456.0
PYH1_k127_6880854_1 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000002094 235.0
PYH1_k127_6880854_2 HEAT repeats - - - 0.00000000000000000000000000000000000000000007729 163.0
PYH1_k127_6892650_0 AAA domain - - - 6.722e-237 758.0
PYH1_k127_6892650_1 Transglutaminase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 345.0
PYH1_k127_6892650_2 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000000000000000009257 204.0
PYH1_k127_6903585_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.671e-218 679.0
PYH1_k127_6903585_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
PYH1_k127_6903585_2 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002232 269.0
PYH1_k127_6903585_3 protein conserved in bacteria K09824 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 0.0000000000000000000000000007738 123.0
PYH1_k127_6903585_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000009258 109.0
PYH1_k127_6940360_0 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 9.444e-298 920.0
PYH1_k127_6940360_1 Glycosyltransferase like family 2 K20444 - - 2.519e-215 677.0
PYH1_k127_6940360_10 Glycosyl transferase, family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 332.0
PYH1_k127_6940360_11 PhoU family K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 302.0
PYH1_k127_6940360_12 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 292.0
PYH1_k127_6940360_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001321 282.0
PYH1_k127_6940360_15 group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
PYH1_k127_6940360_17 - - - - 0.0003438 43.0
PYH1_k127_6940360_2 Bacterial sugar transferase K00996 - 2.7.8.6 7.963e-206 648.0
PYH1_k127_6940360_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 3.286e-195 611.0
PYH1_k127_6940360_4 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 571.0
PYH1_k127_6940360_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 562.0
PYH1_k127_6940360_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 552.0
PYH1_k127_6940360_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 500.0
PYH1_k127_6940360_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 494.0
PYH1_k127_6940360_9 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 494.0
PYH1_k127_6952781_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 486.0
PYH1_k127_6952781_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 301.0
PYH1_k127_6952781_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000003047 91.0
PYH1_k127_7008539_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1061.0
PYH1_k127_7008539_1 chemotaxis protein K03407 - 2.7.13.3 0.0 1022.0
PYH1_k127_7008539_10 GGDEF domain - GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 424.0
PYH1_k127_7008539_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 407.0
PYH1_k127_7008539_12 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 406.0
PYH1_k127_7008539_13 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 312.0
PYH1_k127_7008539_14 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 293.0
PYH1_k127_7008539_15 Chemotaxis protein CheW K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001324 267.0
PYH1_k127_7008539_16 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
PYH1_k127_7008539_17 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005111 276.0
PYH1_k127_7008539_18 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000001876 213.0
PYH1_k127_7008539_19 - - - - 0.000000000000000000000000000000000000000000000000000002124 196.0
PYH1_k127_7008539_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 1.29e-199 625.0
PYH1_k127_7008539_20 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000008021 201.0
PYH1_k127_7008539_21 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000001209 160.0
PYH1_k127_7008539_22 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000004914 147.0
PYH1_k127_7008539_23 diguanylate cyclase - - - 0.00000000000000000000000000000277 136.0
PYH1_k127_7008539_24 CHAD - - - 0.0000004377 61.0
PYH1_k127_7008539_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 4.593e-195 612.0
PYH1_k127_7008539_4 Heterodisulfide reductase subunit B K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 576.0
PYH1_k127_7008539_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 578.0
PYH1_k127_7008539_6 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 529.0
PYH1_k127_7008539_7 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 512.0
PYH1_k127_7008539_8 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 486.0
PYH1_k127_7008539_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 417.0
PYH1_k127_7030429_0 Thiol disulfide interchange protein K04084 - 1.8.1.8 1.275e-261 818.0
PYH1_k127_7030429_1 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000000000000001579 228.0
PYH1_k127_7030429_2 PFAM DsrE family protein K06039 - - 0.00000000000000000000000000000000000000000000000000000000000000001169 225.0
PYH1_k127_7030429_3 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000002239 166.0
PYH1_k127_7030429_4 Rhodanese Homology Domain - - - 0.000000000000000008526 82.0
PYH1_k127_7030429_5 Domain of unknown function DUF302 K12308 - 3.2.1.23 0.00000003199 62.0
PYH1_k127_7061152_0 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 391.0
PYH1_k127_7061152_1 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 316.0
PYH1_k127_7061152_2 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 230.0
PYH1_k127_7061152_3 - - - - 0.00000000000000000000000000000000000000000000000000006914 190.0
PYH1_k127_7061152_4 - - - - 0.000000000000000000000000000000000000000000001461 166.0
PYH1_k127_7098825_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 1.206e-276 857.0
PYH1_k127_7098825_1 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 364.0
PYH1_k127_7098825_2 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000004426 194.0
PYH1_k127_7551801_0 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1303.0
PYH1_k127_7551801_1 ATPase (AAA - - - 0.0 1047.0
PYH1_k127_7551801_10 DnaJ domain protein K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 426.0
PYH1_k127_7551801_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 349.0
PYH1_k127_7551801_12 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 294.0
PYH1_k127_7551801_13 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000264 250.0
PYH1_k127_7551801_14 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000004844 154.0
PYH1_k127_7551801_15 - - - - 0.00000000000000000000000000000000000001122 150.0
PYH1_k127_7551801_16 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.0000000000000000000000000000004607 123.0
PYH1_k127_7551801_17 NADH dehydrogenase (ubiquinone) activity K00330 - 1.6.5.3 0.000000000000009548 79.0
PYH1_k127_7551801_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.751e-263 812.0
PYH1_k127_7551801_3 COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 4.454e-206 645.0
PYH1_k127_7551801_4 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 9.508e-196 618.0
PYH1_k127_7551801_5 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 601.0
PYH1_k127_7551801_6 Hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 530.0
PYH1_k127_7551801_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 517.0
PYH1_k127_7551801_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 488.0
PYH1_k127_7551801_9 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 478.0
PYH1_k127_7562294_0 Mg chelatase-related protein K07391 - - 1.349e-257 805.0
PYH1_k127_7562294_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.678e-228 712.0
PYH1_k127_7562294_2 Domain of Unknown Function (DUF748) - - - 2.876e-213 675.0
PYH1_k127_7562294_3 Belongs to the UPF0324 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 516.0
PYH1_k127_7562294_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
PYH1_k127_7562294_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 380.0
PYH1_k127_7562294_6 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 350.0
PYH1_k127_7562294_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 264.0
PYH1_k127_7562294_8 ATP synthase K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000007453 237.0
PYH1_k127_7604465_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 540.0
PYH1_k127_7604465_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 362.0
PYH1_k127_7604465_2 WG containing repeat - - - 0.00000000000000000000005045 110.0
PYH1_k127_7606318_0 ATPases associated with a variety of cellular activities K02010,K02017,K11076 - 3.6.3.29,3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 284.0
PYH1_k127_7606318_1 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001993 270.0
PYH1_k127_7606318_2 Pyruvate phosphate dikinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 264.0
PYH1_k127_7606318_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000001704 191.0
PYH1_k127_7606318_4 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000006998 117.0
PYH1_k127_7619304_0 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 529.0
PYH1_k127_7619304_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 451.0
PYH1_k127_7619304_2 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 426.0
PYH1_k127_7619304_3 beta-lactamase activity K07126,K15474 - - 0.000000000000000000000000000000000000000001704 156.0
PYH1_k127_7619304_4 AF0941-like - - - 0.000000000000000000000000000000000000000003119 158.0
PYH1_k127_7619304_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000001033 116.0
PYH1_k127_7619304_6 - - - - 0.0000000000000000000000006002 109.0
PYH1_k127_7731452_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 9.96e-258 796.0
PYH1_k127_7731452_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 7.673e-242 756.0
PYH1_k127_7731452_10 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 413.0
PYH1_k127_7731452_11 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 349.0
PYH1_k127_7731452_12 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 327.0
PYH1_k127_7731452_13 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 314.0
PYH1_k127_7731452_14 PFAM Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 286.0
PYH1_k127_7731452_15 AMIN domain - - - 0.0000000000000000000000000000000000000000000000000000001418 200.0
PYH1_k127_7731452_16 Flagellar biosynthetic protein FliQ K02420 - - 0.0000000000000000000000000000000000000000001609 159.0
PYH1_k127_7731452_17 - - - - 0.0000000000000000000000000000000002042 134.0
PYH1_k127_7731452_18 - - - - 0.00000000000000000000002507 102.0
PYH1_k127_7731452_19 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000002468 90.0
PYH1_k127_7731452_2 Cytochrome c oxidase accessory protein - - - 8.879e-231 721.0
PYH1_k127_7731452_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 1.437e-203 636.0
PYH1_k127_7731452_4 TonB dependent receptor K16092 - - 8.226e-199 636.0
PYH1_k127_7731452_5 RNA-binding protein homologous to eukaryotic snRNP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 559.0
PYH1_k127_7731452_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 518.0
PYH1_k127_7731452_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 507.0
PYH1_k127_7731452_8 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 498.0
PYH1_k127_7731452_9 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 436.0
PYH1_k127_7756536_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.581e-257 796.0
PYH1_k127_7756536_1 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 602.0
PYH1_k127_7756536_2 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 394.0
PYH1_k127_7756536_3 signal transduction response regulator (GGDEF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002515 264.0
PYH1_k127_7756536_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000005611 256.0
PYH1_k127_7756536_5 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000009306 168.0
PYH1_k127_7756536_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000002015 70.0
PYH1_k127_776992_0 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1243.0
PYH1_k127_776992_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 4.033e-312 963.0
PYH1_k127_776992_10 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000005605 104.0
PYH1_k127_776992_11 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000002238 65.0
PYH1_k127_776992_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K14086 - - 7.928e-240 754.0
PYH1_k127_776992_3 Hydrogenase-4, component G K14090 - - 1.798e-212 662.0
PYH1_k127_776992_4 NADH dehydrogenase K14087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 450.0
PYH1_k127_776992_5 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 410.0
PYH1_k127_776992_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 334.0
PYH1_k127_776992_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K14091 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
PYH1_k127_776992_8 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000762 192.0
PYH1_k127_776992_9 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000004424 184.0
PYH1_k127_7780335_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 465.0
PYH1_k127_7780335_1 - K21817 - 1.13.11.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 405.0
PYH1_k127_7780335_2 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 267.0
PYH1_k127_7780335_3 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004365 256.0
PYH1_k127_7796330_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1206.0
PYH1_k127_7796330_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 565.0
PYH1_k127_7796330_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 411.0
PYH1_k127_7796330_3 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 380.0
PYH1_k127_7796330_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000008081 134.0
PYH1_k127_7850343_0 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 571.0
PYH1_k127_7850343_1 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 465.0
PYH1_k127_7850343_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000001212 68.0
PYH1_k127_7907200_0 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 591.0
PYH1_k127_7907200_1 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 435.0
PYH1_k127_7907200_2 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 388.0
PYH1_k127_7907200_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 377.0
PYH1_k127_7907200_4 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 359.0
PYH1_k127_7908034_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 374.0
PYH1_k127_7908034_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000007884 235.0
PYH1_k127_7908034_3 Protein of unknown function (DUF3365) - - - 0.00000000000000000000005023 111.0
PYH1_k127_7914299_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 3.879e-262 814.0
PYH1_k127_7914299_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.518e-227 713.0
PYH1_k127_7914299_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.481e-201 638.0
PYH1_k127_7914299_3 COGs COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 366.0
PYH1_k127_7914299_4 COG1085 Galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000001406 116.0
PYH1_k127_8025699_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0 1617.0
PYH1_k127_8025699_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 1.623e-273 860.0
PYH1_k127_8025699_10 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 397.0
PYH1_k127_8025699_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 381.0
PYH1_k127_8025699_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005773 225.0
PYH1_k127_8025699_13 17 kDa surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000013 219.0
PYH1_k127_8025699_14 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000006272 199.0
PYH1_k127_8025699_15 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000006405 154.0
PYH1_k127_8025699_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000002888 142.0
PYH1_k127_8025699_17 Histidine kinase - - - 0.0000000000000000000000000000000000003804 146.0
PYH1_k127_8025699_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 1.381e-245 781.0
PYH1_k127_8025699_3 twitching motility protein K02669 - - 6.887e-205 641.0
PYH1_k127_8025699_4 chemotaxis protein - - - 1.289e-199 632.0
PYH1_k127_8025699_5 Belongs to the GPI family K01810 - 5.3.1.9 2.174e-196 619.0
PYH1_k127_8025699_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 595.0
PYH1_k127_8025699_7 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 591.0
PYH1_k127_8025699_8 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 500.0
PYH1_k127_8025699_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 474.0
PYH1_k127_8034705_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 7.656e-251 777.0
PYH1_k127_8034705_1 Participates in both transcription termination and antitermination K02600 - - 8.654e-205 641.0
PYH1_k127_8034705_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
PYH1_k127_8034705_11 protein conserved in bacteria K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 256.0
PYH1_k127_8034705_12 PFAM Fimbrial assembly family protein - - - 0.00000000000000000000000000000000000000000000000000000000000007834 217.0
PYH1_k127_8034705_13 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
PYH1_k127_8034705_14 - - - - 0.0000000000000000000000000000000000000003977 149.0
PYH1_k127_8034705_15 - - - - 0.0000000000000000000000000000000000004422 143.0
PYH1_k127_8034705_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 548.0
PYH1_k127_8034705_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 542.0
PYH1_k127_8034705_4 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 537.0
PYH1_k127_8034705_5 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 533.0
PYH1_k127_8034705_6 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 511.0
PYH1_k127_8034705_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
PYH1_k127_8034705_8 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
PYH1_k127_8034705_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 358.0
PYH1_k127_8087819_0 Glycerol-3-phosphate dehydrogenase K11473 - - 1.922e-259 801.0
PYH1_k127_8087819_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 601.0
PYH1_k127_8087819_11 Belongs to the 'phage' integrase family K14059 - - 0.000000000000000000000000007063 115.0
PYH1_k127_8087819_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 535.0
PYH1_k127_8087819_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 496.0
PYH1_k127_8087819_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 434.0
PYH1_k127_8087819_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 415.0
PYH1_k127_8087819_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 385.0
PYH1_k127_8087819_7 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 330.0
PYH1_k127_8087819_8 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000008933 229.0
PYH1_k127_8087819_9 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000006467 205.0
PYH1_k127_80921_0 Sulfatase - - - 0.0 1013.0
PYH1_k127_80921_1 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 3.171e-313 979.0
PYH1_k127_80921_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007017 256.0
PYH1_k127_80921_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000002256 233.0
PYH1_k127_80921_4 Sulfatase K03760 - 2.7.8.43 0.000000000000000000000000002791 115.0
PYH1_k127_8093591_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 6.908e-211 658.0
PYH1_k127_8093591_1 PFAM HI0933 family protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 388.0
PYH1_k127_8093591_2 - - - - 0.000000000000000000000000000000000000000000000002179 188.0
PYH1_k127_8093591_3 - - - - 0.00000000000000000000000000001525 122.0
PYH1_k127_8168402_0 PFAM CheW domain protein - - - 0.0 1356.0
PYH1_k127_8168402_1 Belongs to the UPF0061 (SELO) family - - - 7.97e-200 627.0
PYH1_k127_8168402_2 Belongs to the DNA mismatch repair MutS family K03555 - - 0.0000000000000000000000000000000000000000000000000005139 184.0
PYH1_k127_8185640_0 Ribonuclease K12573 - - 0.0 1085.0
PYH1_k127_8185640_1 flagellar hook-associated protein K02396 - - 5.519e-260 816.0
PYH1_k127_8185640_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 310.0
PYH1_k127_8185640_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 297.0
PYH1_k127_8185640_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009182 276.0
PYH1_k127_8185640_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001089 235.0
PYH1_k127_8185640_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000000001374 228.0
PYH1_k127_8185640_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000001593 214.0
PYH1_k127_8185640_16 - - - - 0.0000000000000000000000000000000000000000000000009858 175.0
PYH1_k127_8185640_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000003612 164.0
PYH1_k127_8185640_18 Rod binding protein - - - 0.000000000000000000000000000000000000000000006634 164.0
PYH1_k127_8185640_19 Anti-sigma-28 factor, FlgM - - - 0.0000000000000000000000000006703 113.0
PYH1_k127_8185640_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.742e-237 736.0
PYH1_k127_8185640_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 558.0
PYH1_k127_8185640_4 DNA polymerase III K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 538.0
PYH1_k127_8185640_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 398.0
PYH1_k127_8185640_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 357.0
PYH1_k127_8185640_7 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 348.0
PYH1_k127_8185640_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 324.0
PYH1_k127_8185640_9 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 316.0
PYH1_k127_8219088_0 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 1.125e-285 878.0
PYH1_k127_8219088_1 ATP citrate synthase K15230 - 2.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 594.0
PYH1_k127_8219088_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 422.0
PYH1_k127_8219088_3 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000137 87.0
PYH1_k127_8258738_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 2.917e-218 679.0
PYH1_k127_8258738_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 483.0
PYH1_k127_8258738_2 TIGRFAM diguanylate cyclase (GGDEF) domain K13069,K13590,K18967 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 423.0
PYH1_k127_8258738_3 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 358.0
PYH1_k127_8258738_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003064 243.0
PYH1_k127_847249_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.846e-234 728.0
PYH1_k127_847249_1 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 282.0
PYH1_k127_847249_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
PYH1_k127_847249_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000007891 79.0
PYH1_k127_847249_4 DNA polymerase III K02341 - 2.7.7.7 0.0000000002637 63.0
PYH1_k127_886912_0 chemotaxis protein - - - 5.751e-237 748.0
PYH1_k127_886912_1 Sulfatase-modifying factor enzyme 1 - - - 3.515e-210 661.0
PYH1_k127_886912_2 Aminotransferase, class I K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 559.0
PYH1_k127_886912_3 PFAM dUTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 400.0
PYH1_k127_886912_4 cofactor binding K09979 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH1_k127_886912_5 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000006214 179.0
PYH1_k127_886912_6 lipid a biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000002646 141.0
PYH1_k127_886912_7 - - - - 0.00000000000000003302 82.0
PYH1_k127_894836_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003927 253.0
PYH1_k127_894836_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000002007 206.0
PYH1_k127_894836_2 PhoQ Sensor K03406 - - 0.000000000000000000000000000000000000000000004854 169.0
PYH1_k127_917583_0 Archaea bacterial proteins of unknown function K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 434.0
PYH1_k127_917583_1 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 430.0
PYH1_k127_917583_2 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 377.0
PYH1_k127_917583_3 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
PYH1_k127_917583_4 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000001347 186.0
PYH1_k127_917583_5 - - - - 0.000000000000000000000000000000000000000000007667 169.0
PYH1_k127_917583_6 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000000000009529 141.0
PYH1_k127_917583_7 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000323 131.0
PYH1_k127_917583_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000004354 64.0
PYH1_k127_96442_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.408e-235 731.0
PYH1_k127_96442_1 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 4.874e-210 658.0
PYH1_k127_96442_2 permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 464.0
PYH1_k127_96442_3 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 392.0
PYH1_k127_96442_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 310.0
PYH1_k127_96442_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 311.0
PYH1_k127_96442_6 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000001344 202.0
PYH1_k127_96442_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000005762 75.0
PYH1_k127_966230_0 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 424.0
PYH1_k127_966230_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 403.0
PYH1_k127_966230_2 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
PYH1_k127_966230_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000002599 132.0
PYH1_k127_967483_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 9.874e-304 935.0
PYH1_k127_967483_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 2.208e-255 789.0
PYH1_k127_967483_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 447.0
PYH1_k127_967483_3 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 386.0
PYH1_k127_967483_4 Domain of unknown function (DUF1882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 334.0
PYH1_k127_967483_5 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
PYH1_k127_967483_6 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 290.0
PYH1_k127_967483_7 Sporulation related domain K03749 - - 0.0000000000000001391 80.0
PYH1_k127_967668_0 Hpt sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 430.0
PYH1_k127_967668_1 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 346.0
PYH1_k127_969661_0 Belongs to the DegT DnrJ EryC1 family K15910 - 2.6.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 600.0
PYH1_k127_969661_1 hmm pf00534 K15914 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 553.0
PYH1_k127_969661_2 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 338.0
PYH1_k127_969661_3 Transferase K15915 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 292.0
PYH1_k127_969661_4 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K15913 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.3.1.203 0.0000000000000000000000000000000000000000000000000001085 193.0
PYH1_k127_969661_5 Oligosaccharyl transferase, STT3 subunit K07151,K17251 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.99.18,2.4.99.19 0.0000000000000000000000000000000002254 134.0
PYH1_k127_969661_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000001134 119.0
PYH1_k127_987245_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1116.0
PYH1_k127_987245_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.56e-268 834.0
PYH1_k127_987245_2 Major Facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 553.0
PYH1_k127_987245_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 355.0
PYH1_k127_987245_4 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
PYH1_k127_987245_5 2'-5' RNA ligase K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000007966 199.0
PYH1_k127_987245_6 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000009329 143.0
PYH1_k127_987245_8 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000006173 111.0