Overview

ID MAG03159
Name PYH1_bin.56
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAKOQB01
Species
Assembly information
Completeness (%) 94.66
Contamination (%) 1.36
GC content (%) 64.0
N50 (bp) 20,932
Genome size (bp) 3,928,812

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3861

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1030247_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.03e-306 965.0
PYH1_k127_1030247_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.353e-302 947.0
PYH1_k127_1030247_10 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
PYH1_k127_1030247_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
PYH1_k127_1030247_12 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000241 209.0
PYH1_k127_1030247_13 CHRD domain - - - 0.0000000000000000000000000000000000000000000000000000003485 200.0
PYH1_k127_1030247_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003707 194.0
PYH1_k127_1030247_15 Histidine kinase - - - 0.000000000000000000001141 109.0
PYH1_k127_1030247_16 Antirepressor K07741 - - 0.0009869 49.0
PYH1_k127_1030247_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.643e-214 672.0
PYH1_k127_1030247_3 Extracellular solute-binding protein K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 595.0
PYH1_k127_1030247_4 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 592.0
PYH1_k127_1030247_5 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 483.0
PYH1_k127_1030247_6 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 451.0
PYH1_k127_1030247_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 418.0
PYH1_k127_1030247_8 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 368.0
PYH1_k127_1030247_9 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH1_k127_1038765_0 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 447.0
PYH1_k127_1038765_1 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 424.0
PYH1_k127_1038765_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000002724 230.0
PYH1_k127_105923_0 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101 - 1.1.2.3 8.836e-211 661.0
PYH1_k127_105923_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000007125 58.0
PYH1_k127_105923_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000004204 52.0
PYH1_k127_1073418_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 2.367e-201 643.0
PYH1_k127_1073418_1 SMART extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
PYH1_k127_1073418_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003315 265.0
PYH1_k127_1073418_3 Aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000001825 233.0
PYH1_k127_1073418_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001813 214.0
PYH1_k127_1073418_5 DNA-binding - - - 0.000000000000000000000000000000000000000000000000000004334 196.0
PYH1_k127_1073418_6 - - - - 0.000000000000000000000000000000000000001319 150.0
PYH1_k127_1073418_7 PIN domain - - - 0.00000000000000000000000000007953 121.0
PYH1_k127_1073418_8 Cytochrome c - - - 0.000000001428 59.0
PYH1_k127_1073418_9 Cytochrome c - - - 0.0000004377 55.0
PYH1_k127_1122067_0 GMP synthase C terminal domain K01951 - 6.3.5.2 3.858e-271 842.0
PYH1_k127_1133022_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 4.705e-242 760.0
PYH1_k127_1133022_1 Hydrogenase K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 424.0
PYH1_k127_1133022_2 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000000001865 236.0
PYH1_k127_1133022_3 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000000000000007621 207.0
PYH1_k127_1133022_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.000000000000000000000000000000000000001261 150.0
PYH1_k127_1133022_5 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000000002056 143.0
PYH1_k127_1133022_6 Hydrogenase expression formation protein K03605 - - 0.000000000000000000000000000000003319 132.0
PYH1_k127_1133022_7 Rubredoxin - - - 0.000000000000000000000000000001235 123.0
PYH1_k127_1133022_8 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000000000000000000008978 119.0
PYH1_k127_1133022_9 Hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000073 111.0
PYH1_k127_1141884_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 483.0
PYH1_k127_1141884_1 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000002745 168.0
PYH1_k127_1141884_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000001839 115.0
PYH1_k127_1141884_3 Histidine kinase - - - 0.000000000000000000004341 95.0
PYH1_k127_1149408_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3201.0
PYH1_k127_1149408_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.725e-206 657.0
PYH1_k127_1149408_10 ABC-type sugar transport system, permease component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 426.0
PYH1_k127_1149408_11 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 406.0
PYH1_k127_1149408_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 404.0
PYH1_k127_1149408_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 370.0
PYH1_k127_1149408_14 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
PYH1_k127_1149408_15 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
PYH1_k127_1149408_16 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 320.0
PYH1_k127_1149408_17 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 327.0
PYH1_k127_1149408_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
PYH1_k127_1149408_19 crp fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000304 281.0
PYH1_k127_1149408_2 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 587.0
PYH1_k127_1149408_20 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007177 287.0
PYH1_k127_1149408_21 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
PYH1_k127_1149408_22 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009121 241.0
PYH1_k127_1149408_23 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000005559 236.0
PYH1_k127_1149408_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
PYH1_k127_1149408_25 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000002114 204.0
PYH1_k127_1149408_26 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH1_k127_1149408_27 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000005099 196.0
PYH1_k127_1149408_28 Regulator K01420 - - 0.000000000000000000000000000000000000000000005755 177.0
PYH1_k127_1149408_29 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000477 171.0
PYH1_k127_1149408_3 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 589.0
PYH1_k127_1149408_30 Rubrerythrin - - - 0.000000000000000000000000000000000000002313 154.0
PYH1_k127_1149408_32 PFAM transport-associated K04065 - - 0.000000000000000000000000000000000001255 141.0
PYH1_k127_1149408_33 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001495 136.0
PYH1_k127_1149408_34 - - - - 0.000000000000000000000000000001788 125.0
PYH1_k127_1149408_35 PFAM transport-associated K04065 - - 0.00000000000000000000000000007992 119.0
PYH1_k127_1149408_36 - - - - 0.0000000000000000000000000004783 114.0
PYH1_k127_1149408_37 - - - - 0.000000000000000000000002281 108.0
PYH1_k127_1149408_38 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000001378 106.0
PYH1_k127_1149408_39 7TM receptor with intracellular HD hydrolase - - - 0.00000000000000000000009101 102.0
PYH1_k127_1149408_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 562.0
PYH1_k127_1149408_40 Glycine zipper 2TM domain K04062 - - 0.00000000000000000001196 98.0
PYH1_k127_1149408_41 - - - - 0.00000000000000001249 91.0
PYH1_k127_1149408_42 - - - - 0.000000000000009145 76.0
PYH1_k127_1149408_43 Protein of unknown function (DUF3096) - - - 0.00000000000002944 73.0
PYH1_k127_1149408_44 Belongs to the UPF0337 (CsbD) family - - - 0.0000002285 57.0
PYH1_k127_1149408_45 - - - - 0.0003371 47.0
PYH1_k127_1149408_46 PFAM AMP-dependent synthetase and ligase - - - 0.0005623 44.0
PYH1_k127_1149408_5 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 556.0
PYH1_k127_1149408_6 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 534.0
PYH1_k127_1149408_7 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 471.0
PYH1_k127_1149408_8 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 477.0
PYH1_k127_1149408_9 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 429.0
PYH1_k127_1175591_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.876e-315 983.0
PYH1_k127_1175591_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 2.418e-244 769.0
PYH1_k127_1175591_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008968 258.0
PYH1_k127_1175591_11 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.0000000000000000000000000000000000000000000001076 175.0
PYH1_k127_1175591_12 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000000135 143.0
PYH1_k127_1175591_13 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000223 150.0
PYH1_k127_1175591_14 Protein of unknown function DUF86 - - - 0.000000000000000000000000000003371 123.0
PYH1_k127_1175591_15 Protein required for attachment to host cells - - - 0.0000000000000001752 85.0
PYH1_k127_1175591_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000009527 51.0
PYH1_k127_1175591_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 4.411e-225 708.0
PYH1_k127_1175591_3 Dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 1.044e-199 627.0
PYH1_k127_1175591_4 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 563.0
PYH1_k127_1175591_5 binding-protein-dependent transport systems inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 477.0
PYH1_k127_1175591_6 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 434.0
PYH1_k127_1175591_7 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 434.0
PYH1_k127_1175591_8 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 335.0
PYH1_k127_1175591_9 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 326.0
PYH1_k127_1197299_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 570.0
PYH1_k127_1197299_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 554.0
PYH1_k127_1197299_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 461.0
PYH1_k127_1197299_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 379.0
PYH1_k127_1197299_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 327.0
PYH1_k127_1197299_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
PYH1_k127_1197299_6 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
PYH1_k127_1197299_7 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000005715 175.0
PYH1_k127_1197299_8 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000005773 145.0
PYH1_k127_1197299_9 Protein of unknown function (DUF2905) - - - 0.00000000000000017 80.0
PYH1_k127_1200740_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.789e-232 722.0
PYH1_k127_1200740_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 490.0
PYH1_k127_1200740_2 beta' subunit K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 481.0
PYH1_k127_1200740_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 374.0
PYH1_k127_1200740_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000003235 161.0
PYH1_k127_1200740_5 Histidine kinase K20974 - 2.7.13.3 0.0000000000000000000000006204 105.0
PYH1_k127_1200740_6 Histidine Phosphotransfer domain - - - 0.0000000000000000000003152 99.0
PYH1_k127_1200740_7 Helix-hairpin-helix motif K02237 - - 0.0000000000000000001716 96.0
PYH1_k127_1200740_8 Winged helix-turn helix - - - 0.0000000817 54.0
PYH1_k127_1200740_9 Lipopolysaccharide assembly protein A domain K08992 - - 0.0001322 50.0
PYH1_k127_1209040_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 338.0
PYH1_k127_1209040_1 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 327.0
PYH1_k127_1209040_2 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000004128 138.0
PYH1_k127_1209040_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000002545 113.0
PYH1_k127_1209040_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000149 76.0
PYH1_k127_1209040_5 nuclease K01174 - 3.1.31.1 0.000000005052 59.0
PYH1_k127_1270855_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 513.0
PYH1_k127_1270855_1 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 502.0
PYH1_k127_1270855_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 431.0
PYH1_k127_1270855_3 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 346.0
PYH1_k127_1270855_4 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
PYH1_k127_1270855_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009173 257.0
PYH1_k127_1270855_6 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 238.0
PYH1_k127_1270855_7 PFAM BLUF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001024 210.0
PYH1_k127_1270855_8 transcriptional regulator - - - 0.000000006279 59.0
PYH1_k127_1311137_0 arylsulfatase A K01130 - 3.1.6.1 1.036e-279 867.0
PYH1_k127_1311137_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 629.0
PYH1_k127_1311137_2 response regulator - - - 0.00000000000008934 74.0
PYH1_k127_1333481_0 DNA polymerase K02337 - 2.7.7.7 0.0 1139.0
PYH1_k127_1333481_1 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.271e-270 848.0
PYH1_k127_1333481_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 2.793e-216 687.0
PYH1_k127_1333481_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.239e-205 650.0
PYH1_k127_1333481_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
PYH1_k127_1333481_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
PYH1_k127_1333481_6 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
PYH1_k127_1333481_7 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000003765 222.0
PYH1_k127_1333481_8 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.000000000000000000000000000000000000000000000000000009698 198.0
PYH1_k127_1333481_9 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000001056 205.0
PYH1_k127_1372916_0 histidine kinase A domain protein - - - 0.0 1324.0
PYH1_k127_1372916_1 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 337.0
PYH1_k127_1372916_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000005401 190.0
PYH1_k127_1372916_3 - - - - 0.000000000000000002806 87.0
PYH1_k127_1422297_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1073.0
PYH1_k127_1422297_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 359.0
PYH1_k127_1422297_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 299.0
PYH1_k127_1422297_3 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000805 198.0
PYH1_k127_1471787_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 9.433e-315 979.0
PYH1_k127_1471787_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.693e-224 700.0
PYH1_k127_1471787_10 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000001136 124.0
PYH1_k127_1471787_11 Trm112p-like protein K09791 - - 0.00000000000000000000006548 99.0
PYH1_k127_1471787_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.104e-212 672.0
PYH1_k127_1471787_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 346.0
PYH1_k127_1471787_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 317.0
PYH1_k127_1471787_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 305.0
PYH1_k127_1471787_6 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000001932 223.0
PYH1_k127_1471787_7 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000003564 213.0
PYH1_k127_1471787_8 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000016 147.0
PYH1_k127_1471787_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000002257 129.0
PYH1_k127_14721_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 1e-323 996.0
PYH1_k127_14721_1 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 1.666e-206 647.0
PYH1_k127_14721_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 458.0
PYH1_k127_14721_3 Succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 334.0
PYH1_k127_14721_4 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
PYH1_k127_14721_5 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000001526 278.0
PYH1_k127_14721_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001164 178.0
PYH1_k127_14721_7 Hydrogenase maturation protease K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000001886 141.0
PYH1_k127_14721_8 Helix-turn-helix K21498 - - 0.0000000000000000000002486 108.0
PYH1_k127_14721_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000002614 109.0
PYH1_k127_1597623_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1091.0
PYH1_k127_1597623_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1014.0
PYH1_k127_1597623_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.607e-247 767.0
PYH1_k127_1597623_11 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.276e-245 766.0
PYH1_k127_1597623_12 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.868e-242 751.0
PYH1_k127_1597623_13 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.168e-227 721.0
PYH1_k127_1597623_14 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.261e-223 706.0
PYH1_k127_1597623_15 GMC oxidoreductase - - - 6.774e-222 700.0
PYH1_k127_1597623_16 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.627e-213 679.0
PYH1_k127_1597623_17 SAF - - - 8.482e-210 661.0
PYH1_k127_1597623_18 Methionine gamma-lyase K01761 - 4.4.1.11 2.179e-209 660.0
PYH1_k127_1597623_19 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 561.0
PYH1_k127_1597623_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 4.3e-322 1001.0
PYH1_k127_1597623_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 575.0
PYH1_k127_1597623_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 545.0
PYH1_k127_1597623_22 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 499.0
PYH1_k127_1597623_23 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 487.0
PYH1_k127_1597623_24 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 488.0
PYH1_k127_1597623_25 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
PYH1_k127_1597623_26 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 469.0
PYH1_k127_1597623_27 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 457.0
PYH1_k127_1597623_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 387.0
PYH1_k127_1597623_29 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 389.0
PYH1_k127_1597623_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.82e-318 981.0
PYH1_k127_1597623_30 transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 352.0
PYH1_k127_1597623_31 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 353.0
PYH1_k127_1597623_32 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 342.0
PYH1_k127_1597623_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 325.0
PYH1_k127_1597623_35 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 318.0
PYH1_k127_1597623_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 312.0
PYH1_k127_1597623_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
PYH1_k127_1597623_38 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
PYH1_k127_1597623_39 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 281.0
PYH1_k127_1597623_4 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 2.034e-311 966.0
PYH1_k127_1597623_40 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001155 275.0
PYH1_k127_1597623_41 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
PYH1_k127_1597623_42 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
PYH1_k127_1597623_43 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003393 236.0
PYH1_k127_1597623_44 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
PYH1_k127_1597623_45 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000001659 212.0
PYH1_k127_1597623_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001531 199.0
PYH1_k127_1597623_47 - - - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
PYH1_k127_1597623_48 glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000001755 174.0
PYH1_k127_1597623_49 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000002138 181.0
PYH1_k127_1597623_5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 8.093e-302 935.0
PYH1_k127_1597623_50 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000007758 175.0
PYH1_k127_1597623_51 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000001094 160.0
PYH1_k127_1597623_52 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000006137 154.0
PYH1_k127_1597623_53 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000003237 151.0
PYH1_k127_1597623_54 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000007452 143.0
PYH1_k127_1597623_55 Twin-arginine translocation pathway signal protein - - - 0.0000000000000000000000000000000004461 138.0
PYH1_k127_1597623_56 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000005561 127.0
PYH1_k127_1597623_57 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000002116 131.0
PYH1_k127_1597623_58 PFAM RDD domain containing protein - - - 0.0000000000000000000000000002122 121.0
PYH1_k127_1597623_59 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000008787 109.0
PYH1_k127_1597623_6 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.041e-280 871.0
PYH1_k127_1597623_60 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000001903 107.0
PYH1_k127_1597623_61 Protein of unknown function (DUF3106) - - - 0.000000000000000004375 91.0
PYH1_k127_1597623_62 Protein of unknown function (DUF3619) - - - 0.00000000003347 72.0
PYH1_k127_1597623_7 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.253e-266 826.0
PYH1_k127_1597623_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.434e-256 792.0
PYH1_k127_1597623_9 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.691e-248 780.0
PYH1_k127_1636221_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 4.415e-204 640.0
PYH1_k127_1636221_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 452.0
PYH1_k127_1636221_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
PYH1_k127_1636221_3 enoyl-CoA hydratase - - - 0.00000000000000000001401 91.0
PYH1_k127_1670047_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.719e-292 915.0
PYH1_k127_1670047_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 3.883e-243 761.0
PYH1_k127_1670047_10 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 491.0
PYH1_k127_1670047_11 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
PYH1_k127_1670047_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 432.0
PYH1_k127_1670047_13 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 408.0
PYH1_k127_1670047_14 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 413.0
PYH1_k127_1670047_15 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 387.0
PYH1_k127_1670047_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 327.0
PYH1_k127_1670047_17 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005932 280.0
PYH1_k127_1670047_18 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001275 261.0
PYH1_k127_1670047_19 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
PYH1_k127_1670047_2 Aminotransferase K14261 - - 4.698e-227 707.0
PYH1_k127_1670047_20 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000006125 250.0
PYH1_k127_1670047_21 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002433 241.0
PYH1_k127_1670047_22 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
PYH1_k127_1670047_23 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
PYH1_k127_1670047_24 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000005638 203.0
PYH1_k127_1670047_25 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000003049 193.0
PYH1_k127_1670047_26 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000004759 185.0
PYH1_k127_1670047_27 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000004424 184.0
PYH1_k127_1670047_28 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000002057 160.0
PYH1_k127_1670047_29 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000001806 147.0
PYH1_k127_1670047_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.546e-219 687.0
PYH1_k127_1670047_30 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000004239 142.0
PYH1_k127_1670047_31 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000000000001475 107.0
PYH1_k127_1670047_32 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000005439 93.0
PYH1_k127_1670047_33 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000001276 87.0
PYH1_k127_1670047_34 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.00000000000005627 72.0
PYH1_k127_1670047_35 protein conserved in bacteria K09937 - - 0.00000000000009749 74.0
PYH1_k127_1670047_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.557e-199 629.0
PYH1_k127_1670047_5 Threonine synthase K01733 - 4.2.3.1 2.908e-197 625.0
PYH1_k127_1670047_6 homoserine dehydrogenase K00003 - 1.1.1.3 8.799e-197 623.0
PYH1_k127_1670047_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
PYH1_k127_1670047_8 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 564.0
PYH1_k127_1670047_9 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 522.0
PYH1_k127_1685699_0 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000001868 148.0
PYH1_k127_1685699_1 peptidase - - - 0.00000000000000000000000000000000007861 137.0
PYH1_k127_1685699_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000143 110.0
PYH1_k127_1685699_3 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000000006456 102.0
PYH1_k127_1685699_4 positive regulation of growth - - - 0.0000000000000000003705 88.0
PYH1_k127_1685699_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000001775 61.0
PYH1_k127_1685699_6 PIN domain - - - 0.0007487 45.0
PYH1_k127_1693058_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 576.0
PYH1_k127_1693058_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 498.0
PYH1_k127_1693058_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 411.0
PYH1_k127_1693058_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 336.0
PYH1_k127_1693058_4 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 322.0
PYH1_k127_1693058_5 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003792 241.0
PYH1_k127_1693058_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000007955 196.0
PYH1_k127_1693058_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000008684 190.0
PYH1_k127_1693058_8 NHL repeat - - - 0.0000000000000000000000000000000000000000001335 164.0
PYH1_k127_1730401_0 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 1.425e-266 833.0
PYH1_k127_1730401_1 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000003864 227.0
PYH1_k127_1730401_2 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000000000244 205.0
PYH1_k127_1730401_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000004459 199.0
PYH1_k127_1742100_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1020.0
PYH1_k127_1742100_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1019.0
PYH1_k127_1742100_10 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 525.0
PYH1_k127_1742100_11 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 537.0
PYH1_k127_1742100_12 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 517.0
PYH1_k127_1742100_13 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 496.0
PYH1_k127_1742100_14 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 483.0
PYH1_k127_1742100_15 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 475.0
PYH1_k127_1742100_16 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
PYH1_k127_1742100_17 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 444.0
PYH1_k127_1742100_18 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 434.0
PYH1_k127_1742100_19 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 418.0
PYH1_k127_1742100_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1015.0
PYH1_k127_1742100_20 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 418.0
PYH1_k127_1742100_21 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 412.0
PYH1_k127_1742100_22 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 356.0
PYH1_k127_1742100_23 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 357.0
PYH1_k127_1742100_24 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
PYH1_k127_1742100_25 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 288.0
PYH1_k127_1742100_26 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 293.0
PYH1_k127_1742100_27 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001189 287.0
PYH1_k127_1742100_28 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000278 265.0
PYH1_k127_1742100_29 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 256.0
PYH1_k127_1742100_3 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 2.063e-288 918.0
PYH1_k127_1742100_30 lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007351 253.0
PYH1_k127_1742100_31 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000002599 244.0
PYH1_k127_1742100_32 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
PYH1_k127_1742100_33 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008236 242.0
PYH1_k127_1742100_34 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
PYH1_k127_1742100_35 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
PYH1_k127_1742100_36 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000000002238 195.0
PYH1_k127_1742100_37 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001242 201.0
PYH1_k127_1742100_38 DUF218 domain - - - 0.00000000000000000000000000000000000000000000001783 181.0
PYH1_k127_1742100_39 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000001277 171.0
PYH1_k127_1742100_4 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 1.607e-277 864.0
PYH1_k127_1742100_40 NLP P60 protein - - - 0.0000000000000000000000000000000000000002 158.0
PYH1_k127_1742100_41 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000002889 156.0
PYH1_k127_1742100_42 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000008456 151.0
PYH1_k127_1742100_43 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000003381 145.0
PYH1_k127_1742100_44 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000009058 143.0
PYH1_k127_1742100_45 membrane - - - 0.0000000000000000000000000000000000008998 150.0
PYH1_k127_1742100_46 Transposase K07499 - - 0.0000000000000000000000007282 109.0
PYH1_k127_1742100_47 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000546 113.0
PYH1_k127_1742100_48 TM2 domain - - - 0.000000000000000000003841 97.0
PYH1_k127_1742100_49 - - - - 0.000000000000000000008952 98.0
PYH1_k127_1742100_5 PFAM AMP-dependent synthetase and ligase K00666 - - 5.726e-271 842.0
PYH1_k127_1742100_50 Protein conserved in bacteria K09705 - - 0.000000003839 64.0
PYH1_k127_1742100_52 RDD family - - - 0.00005287 50.0
PYH1_k127_1742100_6 Cysteine-rich domain - - - 2.725e-211 664.0
PYH1_k127_1742100_7 Oxidoreductase - - - 3.507e-207 656.0
PYH1_k127_1742100_8 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 620.0
PYH1_k127_1742100_9 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 546.0
PYH1_k127_1748969_0 rhamnose metabolic process - - - 0.0000000000000000000000000000000001711 134.0
PYH1_k127_1748969_1 - - - - 0.000000000000000000000000000000005637 132.0
PYH1_k127_1748969_2 AcrB/AcrD/AcrF family K03296,K18138,K18902 - - 0.000000000000000000000002153 103.0
PYH1_k127_1748969_3 Fibronectin, type III domain - - - 0.00001372 57.0
PYH1_k127_1755002_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 416.0
PYH1_k127_1755002_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 398.0
PYH1_k127_1755002_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.0000000000000000000000000000000000000000000003104 172.0
PYH1_k127_1777163_0 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005798 274.0
PYH1_k127_1777163_1 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000009437 57.0
PYH1_k127_1777163_2 signal transduction protein containing sensor and EAL - - - 0.0000002405 54.0
PYH1_k127_1777163_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0001317 49.0
PYH1_k127_1807326_0 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 5.533e-224 701.0
PYH1_k127_1807326_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 397.0
PYH1_k127_1807326_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
PYH1_k127_1807326_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
PYH1_k127_1807326_4 Belongs to the 'phage' integrase family K14059 - - 0.000000000000000000000000000000000000000002002 160.0
PYH1_k127_1807326_5 Cro/C1-type HTH DNA-binding domain K07727 - - 0.000000000000000000000000573 108.0
PYH1_k127_1807326_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000007405 101.0
PYH1_k127_1807326_7 - - - - 0.00000000009533 64.0
PYH1_k127_1807326_8 Bacteriophage replication gene A protein (GPA) - - - 0.0000000001121 70.0
PYH1_k127_1807326_9 - - - - 0.0000000004449 60.0
PYH1_k127_1811621_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.498e-253 799.0
PYH1_k127_1811621_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 585.0
PYH1_k127_1811621_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 565.0
PYH1_k127_1811621_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 422.0
PYH1_k127_1811621_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
PYH1_k127_1811621_5 Preprotein translocase K03210 - - 0.00000000000000000000000000000001873 130.0
PYH1_k127_1841535_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.738e-206 646.0
PYH1_k127_1841535_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 385.0
PYH1_k127_1841535_2 - - - - 0.0000000000000000000000000000000000000000000000000000000145 201.0
PYH1_k127_1859960_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 566.0
PYH1_k127_1859960_1 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 360.0
PYH1_k127_1859960_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 299.0
PYH1_k127_1859960_3 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 301.0
PYH1_k127_1859960_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000001216 212.0
PYH1_k127_1859960_5 PFAM cytoplasmic chaperone TorD family protein - - - 0.000000000000000000000000000000005405 141.0
PYH1_k127_1876444_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.169e-281 876.0
PYH1_k127_1876444_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.915e-230 727.0
PYH1_k127_1876444_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 474.0
PYH1_k127_1876444_3 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 346.0
PYH1_k127_1876444_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 282.0
PYH1_k127_1876444_5 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002319 246.0
PYH1_k127_1876444_6 TonB C terminal - - - 0.0000000000000000000000009386 117.0
PYH1_k127_1876444_7 - - - - 0.0000002273 58.0
PYH1_k127_1877424_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1298.0
PYH1_k127_1877424_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1262.0
PYH1_k127_1877424_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001885 235.0
PYH1_k127_1877424_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000001038 224.0
PYH1_k127_1877424_12 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000003028 193.0
PYH1_k127_1877424_13 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000001395 157.0
PYH1_k127_1877424_14 TIGRFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000000000000000002132 147.0
PYH1_k127_1877424_15 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000003375 139.0
PYH1_k127_1877424_16 Cold shock protein K03704 - - 0.0000000000000000000000000000000002042 134.0
PYH1_k127_1877424_17 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000002995 101.0
PYH1_k127_1877424_18 cytochrome - - - 0.000000000000000000002817 98.0
PYH1_k127_1877424_2 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.822e-239 743.0
PYH1_k127_1877424_3 sulfide dehydrogenase K05301 - 1.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 511.0
PYH1_k127_1877424_4 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 512.0
PYH1_k127_1877424_5 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 506.0
PYH1_k127_1877424_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 481.0
PYH1_k127_1877424_7 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
PYH1_k127_1877424_8 mechanosensitive K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 349.0
PYH1_k127_1877424_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
PYH1_k127_1886371_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 584.0
PYH1_k127_1886371_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 441.0
PYH1_k127_1886371_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 414.0
PYH1_k127_1886371_3 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
PYH1_k127_1886371_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005599 248.0
PYH1_k127_1886371_5 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000009299 163.0
PYH1_k127_1886371_6 FAD dependent oxidoreductase - - - 0.00000000000000000000009411 98.0
PYH1_k127_1886371_7 Phospholipid methyltransferase - - - 0.000000000000000001141 96.0
PYH1_k127_1886371_8 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000003326 62.0
PYH1_k127_189881_0 B12 binding domain K00548 - 2.1.1.13 0.0 1825.0
PYH1_k127_189881_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1142.0
PYH1_k127_189881_10 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 472.0
PYH1_k127_189881_11 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 462.0
PYH1_k127_189881_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 403.0
PYH1_k127_189881_13 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
PYH1_k127_189881_14 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
PYH1_k127_189881_15 Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 368.0
PYH1_k127_189881_16 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 363.0
PYH1_k127_189881_17 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 356.0
PYH1_k127_189881_18 coenzyme F420-1:gamma-L-glutamate ligase activity K19285,K19286 - 1.5.1.38,1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
PYH1_k127_189881_19 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 339.0
PYH1_k127_189881_2 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.814e-294 915.0
PYH1_k127_189881_20 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 327.0
PYH1_k127_189881_21 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 301.0
PYH1_k127_189881_22 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 294.0
PYH1_k127_189881_23 sequence-specific DNA binding K05804,K13631,K13632,K18325,K19056 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009635,GO:0009636,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032787,GO:0032991,GO:0032993,GO:0035690,GO:0036245,GO:0042180,GO:0042182,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046185,GO:0046394,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051596,GO:0051716,GO:0060255,GO:0061727,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0072330,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:0140110,GO:1901363,GO:1901562,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006823 287.0
PYH1_k127_189881_24 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
PYH1_k127_189881_25 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000625 273.0
PYH1_k127_189881_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001693 254.0
PYH1_k127_189881_27 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000005626 250.0
PYH1_k127_189881_28 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000003056 244.0
PYH1_k127_189881_29 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000166 248.0
PYH1_k127_189881_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.968e-256 813.0
PYH1_k127_189881_30 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
PYH1_k127_189881_31 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000003567 205.0
PYH1_k127_189881_32 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000001395 192.0
PYH1_k127_189881_33 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000003291 167.0
PYH1_k127_189881_34 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000001056 169.0
PYH1_k127_189881_35 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000001576 159.0
PYH1_k127_189881_36 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000002532 131.0
PYH1_k127_189881_37 - - - - 0.0000000000000000000000000007444 119.0
PYH1_k127_189881_38 Protein of unknown function (DUF3567) - - - 0.0000000000000000000001598 108.0
PYH1_k127_189881_39 PFAM EAL domain protein - - - 0.00000000000003715 87.0
PYH1_k127_189881_4 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 7.862e-213 685.0
PYH1_k127_189881_40 cobalamin synthesis protein - - - 0.00000001421 61.0
PYH1_k127_189881_41 response regulator - - - 0.00006446 47.0
PYH1_k127_189881_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.501e-205 647.0
PYH1_k127_189881_6 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 617.0
PYH1_k127_189881_7 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 592.0
PYH1_k127_189881_8 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 567.0
PYH1_k127_189881_9 Beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 481.0
PYH1_k127_1901237_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.968e-290 897.0
PYH1_k127_1901237_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 1.456e-207 653.0
PYH1_k127_1901237_10 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000003012 186.0
PYH1_k127_1901237_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000002075 172.0
PYH1_k127_1901237_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000001306 176.0
PYH1_k127_1901237_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000001542 139.0
PYH1_k127_1901237_14 CheW-like domain K02659 - - 0.0000000000000000000000000000003668 129.0
PYH1_k127_1901237_15 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000442 119.0
PYH1_k127_1901237_16 CRISPR_assoc - - - 0.00001269 55.0
PYH1_k127_1901237_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 576.0
PYH1_k127_1901237_3 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 545.0
PYH1_k127_1901237_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 474.0
PYH1_k127_1901237_5 Histidine kinase K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 338.0
PYH1_k127_1901237_6 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
PYH1_k127_1901237_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000001886 245.0
PYH1_k127_1901237_8 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
PYH1_k127_1901237_9 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000004054 215.0
PYH1_k127_190301_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2721.0
PYH1_k127_190301_1 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1275.0
PYH1_k127_190301_10 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000004232 198.0
PYH1_k127_190301_11 Belongs to the 'phage' integrase family - - - 0.00000000000000000003317 92.0
PYH1_k127_190301_2 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 1.042e-215 683.0
PYH1_k127_190301_3 Magnesium transport protein CorA - - - 1.939e-204 659.0
PYH1_k127_190301_4 COG4974 Site-specific recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
PYH1_k127_190301_5 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 381.0
PYH1_k127_190301_6 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
PYH1_k127_190301_7 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 363.0
PYH1_k127_190301_8 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 359.0
PYH1_k127_190301_9 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
PYH1_k127_192041_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 8.676e-240 761.0
PYH1_k127_192041_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.526e-206 649.0
PYH1_k127_192041_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 546.0
PYH1_k127_192041_3 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000007196 217.0
PYH1_k127_192041_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000118 128.0
PYH1_k127_192041_5 metal cluster binding - - - 0.0000000000000000000009446 102.0
PYH1_k127_1926316_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.647e-200 638.0
PYH1_k127_1926316_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 496.0
PYH1_k127_1926316_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 474.0
PYH1_k127_1926316_3 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 445.0
PYH1_k127_1926316_4 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000000000000000000000000000000000000004557 228.0
PYH1_k127_1926316_5 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001325 211.0
PYH1_k127_1926316_6 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000006058 216.0
PYH1_k127_1926316_7 - - - - 0.0000000000000000000000000000000000000000000002917 180.0
PYH1_k127_1926316_8 - - - - 0.0000000000000000000000000000000003071 144.0
PYH1_k127_1926316_9 s cog2930 - - - 0.000000000000001004 77.0
PYH1_k127_1929460_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000006014 200.0
PYH1_k127_1929460_1 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000005578 129.0
PYH1_k127_1929460_2 DsrE/DsrF-like family - - - 0.000000000000000000000007357 107.0
PYH1_k127_1929460_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000004255 105.0
PYH1_k127_1929460_4 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000007086 98.0
PYH1_k127_1931939_0 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.362e-256 794.0
PYH1_k127_1931939_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 4.851e-200 630.0
PYH1_k127_1931939_2 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 416.0
PYH1_k127_1995578_0 Belongs to the ABC transporter superfamily K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 435.0
PYH1_k127_1995578_1 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
PYH1_k127_1995578_2 COG1176 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 381.0
PYH1_k127_1995578_3 transcriptional - - - 0.0000000000000000000000000000000000000000001134 170.0
PYH1_k127_1995578_4 Acyl-transferase - - - 0.0000000000000000000000003264 107.0
PYH1_k127_1995578_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000001107 98.0
PYH1_k127_2026811_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1219.0
PYH1_k127_2026811_1 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 1.391e-229 733.0
PYH1_k127_2026811_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000002548 73.0
PYH1_k127_2026811_11 - - - - 0.000000002124 62.0
PYH1_k127_2026811_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000351 61.0
PYH1_k127_2026811_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 9.377e-208 661.0
PYH1_k127_2026811_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 606.0
PYH1_k127_2026811_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 543.0
PYH1_k127_2026811_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 469.0
PYH1_k127_2026811_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 385.0
PYH1_k127_2026811_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 317.0
PYH1_k127_2026811_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006107 280.0
PYH1_k127_2026811_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000002367 117.0
PYH1_k127_2069346_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.573e-312 969.0
PYH1_k127_2069346_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.487e-293 907.0
PYH1_k127_2069346_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 464.0
PYH1_k127_2069346_3 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
PYH1_k127_2069346_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 445.0
PYH1_k127_2069346_5 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
PYH1_k127_2069346_6 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 357.0
PYH1_k127_2069346_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001573 280.0
PYH1_k127_2069346_8 Cytochrome K08738 - - 0.0000000000000000000000000000000001356 134.0
PYH1_k127_2069346_9 - - - - 0.0000000000001476 73.0
PYH1_k127_2091481_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 398.0
PYH1_k127_2091481_1 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 338.0
PYH1_k127_2091481_2 Domain of unknown function (DUF309) - - - 0.0000000000000000000001961 97.0
PYH1_k127_2093668_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1406.0
PYH1_k127_2093668_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 510.0
PYH1_k127_2093668_2 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 475.0
PYH1_k127_2093668_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 473.0
PYH1_k127_2093668_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 289.0
PYH1_k127_2093668_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
PYH1_k127_2093668_6 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
PYH1_k127_2094315_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.494e-276 860.0
PYH1_k127_2094315_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.868e-262 833.0
PYH1_k127_2094315_10 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
PYH1_k127_2094315_11 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 287.0
PYH1_k127_2094315_12 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 281.0
PYH1_k127_2094315_13 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000002095 246.0
PYH1_k127_2094315_14 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
PYH1_k127_2094315_15 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000001623 162.0
PYH1_k127_2094315_16 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000009225 156.0
PYH1_k127_2094315_17 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000154 140.0
PYH1_k127_2094315_18 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000004039 130.0
PYH1_k127_2094315_19 membrane K08972 - - 0.0000000000000000000000000000001311 129.0
PYH1_k127_2094315_2 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 589.0
PYH1_k127_2094315_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 565.0
PYH1_k127_2094315_4 Soluble lytic murein K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 569.0
PYH1_k127_2094315_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 506.0
PYH1_k127_2094315_6 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 491.0
PYH1_k127_2094315_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 437.0
PYH1_k127_2094315_8 succinylglutamate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 411.0
PYH1_k127_2094315_9 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 411.0
PYH1_k127_2190137_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.32e-251 783.0
PYH1_k127_2190137_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.104e-227 708.0
PYH1_k127_2190137_10 LysM domain K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 311.0
PYH1_k127_2190137_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000005875 215.0
PYH1_k127_2190137_12 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000000000000005391 190.0
PYH1_k127_2190137_13 Sporulation related domain K03749 - - 0.0000000000000000000000124 110.0
PYH1_k127_2190137_14 Colicin V production protein K03558 - - 0.000000000000000000002029 102.0
PYH1_k127_2190137_15 Helix-hairpin-helix motif - - - 0.000000000000000000005388 96.0
PYH1_k127_2190137_16 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.00000000000000000146 89.0
PYH1_k127_2190137_17 - - - - 0.0000000000000008731 88.0
PYH1_k127_2190137_19 Domain of unknown function (DUF932) - - - 0.000134 44.0
PYH1_k127_2190137_2 Retron-type reverse transcriptase K00986 - 2.7.7.49 1.5e-204 653.0
PYH1_k127_2190137_3 Epoxide hydrolase N terminus K01253 - 3.3.2.9 9.097e-196 618.0
PYH1_k127_2190137_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 571.0
PYH1_k127_2190137_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 512.0
PYH1_k127_2190137_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 488.0
PYH1_k127_2190137_7 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 373.0
PYH1_k127_2190137_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
PYH1_k127_2190137_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
PYH1_k127_2230419_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 599.0
PYH1_k127_2230419_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000007257 83.0
PYH1_k127_2257532_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 541.0
PYH1_k127_2257532_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 389.0
PYH1_k127_2257532_2 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000006246 107.0
PYH1_k127_2257532_3 - - - - 0.000000000000000000002913 102.0
PYH1_k127_2257532_4 - - - - 0.0000000000000001529 83.0
PYH1_k127_2259192_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 4.124e-246 764.0
PYH1_k127_2259192_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.511e-209 665.0
PYH1_k127_2259192_2 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000004114 173.0
PYH1_k127_2259192_3 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000001131 152.0
PYH1_k127_2259192_4 Cas6 Crispr - - - 0.000000000000000000000000000000000000002172 157.0
PYH1_k127_2259192_5 - - - - 0.000000000000000000001394 97.0
PYH1_k127_2274154_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1743.0
PYH1_k127_2274154_1 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 609.0
PYH1_k127_2274154_2 5-oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 490.0
PYH1_k127_2274154_3 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
PYH1_k127_2274154_4 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 297.0
PYH1_k127_2274154_5 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007748 281.0
PYH1_k127_2274154_6 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002262 247.0
PYH1_k127_2274154_7 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 0.0000000000000000000000000000000000000000000000000004131 186.0
PYH1_k127_2274154_8 - - - - 0.000000000000000000000000000003694 126.0
PYH1_k127_2274154_9 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000049 110.0
PYH1_k127_2287695_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 409.0
PYH1_k127_2287695_1 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 305.0
PYH1_k127_2287695_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 306.0
PYH1_k127_2287695_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000007521 246.0
PYH1_k127_2309989_0 PFAM transposase, IS4 family protein K07481 - - 6.839e-204 644.0
PYH1_k127_2309989_1 DsrE/DsrF/DrsH-like family - - - 0.00000000001578 70.0
PYH1_k127_2376986_0 oxidoreductase K04090 - 1.2.7.8 0.0 1461.0
PYH1_k127_2376986_1 A predicted alpha-helical domain with a conserved ER motif. - - - 2.528e-296 931.0
PYH1_k127_2376986_10 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000001245 199.0
PYH1_k127_2376986_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000005297 158.0
PYH1_k127_2376986_2 transglutaminase domain protein - - - 4.027e-268 829.0
PYH1_k127_2376986_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.981e-257 812.0
PYH1_k127_2376986_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 373.0
PYH1_k127_2376986_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 366.0
PYH1_k127_2376986_6 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
PYH1_k127_2376986_7 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005298 276.0
PYH1_k127_2376986_8 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
PYH1_k127_2376986_9 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000471 211.0
PYH1_k127_239257_0 Transport of potassium into the cell K03549 - - 4.103e-229 726.0
PYH1_k127_239257_1 nucleoside-diphosphate sugar epimerase - - - 5.119e-200 634.0
PYH1_k127_239257_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 502.0
PYH1_k127_239257_3 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 444.0
PYH1_k127_239257_4 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
PYH1_k127_239257_5 permease K07089 - - 0.00000000000000000000000000000000000000751 152.0
PYH1_k127_239257_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000000000000000000000003092 113.0
PYH1_k127_239257_7 Thioredoxin domain - - - 0.0000000000000000004391 89.0
PYH1_k127_244871_0 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 578.0
PYH1_k127_244871_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 352.0
PYH1_k127_2483042_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1759.0
PYH1_k127_2483042_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1277.0
PYH1_k127_2483042_10 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 541.0
PYH1_k127_2483042_11 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 500.0
PYH1_k127_2483042_12 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 475.0
PYH1_k127_2483042_13 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 462.0
PYH1_k127_2483042_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 429.0
PYH1_k127_2483042_15 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 433.0
PYH1_k127_2483042_16 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 396.0
PYH1_k127_2483042_17 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 416.0
PYH1_k127_2483042_18 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
PYH1_k127_2483042_19 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 388.0
PYH1_k127_2483042_2 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 4.492e-217 681.0
PYH1_k127_2483042_20 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 402.0
PYH1_k127_2483042_21 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 349.0
PYH1_k127_2483042_22 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 300.0
PYH1_k127_2483042_23 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002831 259.0
PYH1_k127_2483042_24 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000003586 251.0
PYH1_k127_2483042_25 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000002158 236.0
PYH1_k127_2483042_26 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001436 225.0
PYH1_k127_2483042_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
PYH1_k127_2483042_28 carbohydrate transport K11688 - - 0.000000000000000000000000000000000000000000000000000000000000009581 228.0
PYH1_k127_2483042_29 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000001732 203.0
PYH1_k127_2483042_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 1.779e-209 659.0
PYH1_k127_2483042_30 Thioesterase K07107,K12500 - - 0.0000000000000000000000000000000000000000000000000004185 192.0
PYH1_k127_2483042_31 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000007504 191.0
PYH1_k127_2483042_32 Ribbon-helix-helix domain - - - 0.000000000000000000000000000000000000000003401 157.0
PYH1_k127_2483042_33 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000003273 152.0
PYH1_k127_2483042_34 NUDIX domain - - - 0.00000000000000000000000000007302 124.0
PYH1_k127_2483042_35 SMART Cold shock protein K03704 - - 0.000000000000000000000000001916 112.0
PYH1_k127_2483042_36 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000003954 100.0
PYH1_k127_2483042_37 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000361 95.0
PYH1_k127_2483042_38 FCD - - - 0.000000003809 62.0
PYH1_k127_2483042_4 Transketolase, C-terminal domain K00167 - 1.2.4.4 7.289e-195 612.0
PYH1_k127_2483042_40 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000004319 50.0
PYH1_k127_2483042_41 family) member 1 - - - 0.0003889 48.0
PYH1_k127_2483042_5 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 623.0
PYH1_k127_2483042_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 595.0
PYH1_k127_2483042_7 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 572.0
PYH1_k127_2483042_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 564.0
PYH1_k127_2483042_9 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 545.0
PYH1_k127_2487764_0 cysteine protease - - - 5.167e-233 738.0
PYH1_k127_2487764_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000009476 73.0
PYH1_k127_249387_0 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 579.0
PYH1_k127_249387_1 COG3666 Transposase and inactivated derivatives - - - 0.0000000000001469 70.0
PYH1_k127_2495020_0 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 461.0
PYH1_k127_2495020_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 322.0
PYH1_k127_2495020_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000002289 196.0
PYH1_k127_2495020_3 OsmC-like protein - - - 0.00000000000000000000000000000000001942 140.0
PYH1_k127_2495020_4 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000009238 101.0
PYH1_k127_2495020_5 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000000009011 85.0
PYH1_k127_2517_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 561.0
PYH1_k127_2517_1 Trypsin K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 493.0
PYH1_k127_2517_10 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000002234 193.0
PYH1_k127_2517_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000004526 169.0
PYH1_k127_2517_12 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000005876 157.0
PYH1_k127_2517_13 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000004454 151.0
PYH1_k127_2517_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000001035 129.0
PYH1_k127_2517_15 - - - - 0.00000000000000000000000000000001861 132.0
PYH1_k127_2517_16 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000000008733 111.0
PYH1_k127_2517_17 Heavy-metal resistance - - - 0.00000000000000867 82.0
PYH1_k127_2517_2 rieske 2fe-2s K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 426.0
PYH1_k127_2517_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 419.0
PYH1_k127_2517_4 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 388.0
PYH1_k127_2517_5 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
PYH1_k127_2517_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 345.0
PYH1_k127_2517_7 Two component transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
PYH1_k127_2517_8 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000001568 198.0
PYH1_k127_2517_9 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000001931 195.0
PYH1_k127_2530388_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 542.0
PYH1_k127_2530388_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 484.0
PYH1_k127_2530388_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000002978 179.0
PYH1_k127_2530388_11 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000001977 158.0
PYH1_k127_2530388_12 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000001126 117.0
PYH1_k127_2530388_13 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000001331 121.0
PYH1_k127_2530388_14 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000001648 119.0
PYH1_k127_2530388_15 PFAM MaoC domain protein dehydratase - - - 0.000000000000000428 80.0
PYH1_k127_2530388_16 - - - - 0.00000000002905 70.0
PYH1_k127_2530388_2 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 331.0
PYH1_k127_2530388_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 302.0
PYH1_k127_2530388_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
PYH1_k127_2530388_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000005039 216.0
PYH1_k127_2530388_7 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000001994 190.0
PYH1_k127_2530388_8 regulatory - - - 0.000000000000000000000000000000000000000000000000001463 190.0
PYH1_k127_2530388_9 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000002303 180.0
PYH1_k127_254609_0 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 563.0
PYH1_k127_254609_1 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000005087 124.0
PYH1_k127_2550479_0 AcrB/AcrD/AcrF family - - - 4.075e-217 689.0
PYH1_k127_2550479_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000003887 158.0
PYH1_k127_2554560_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 4.761e-284 881.0
PYH1_k127_2554560_1 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 5.967e-264 825.0
PYH1_k127_2554560_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 298.0
PYH1_k127_2554560_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
PYH1_k127_2554560_12 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 258.0
PYH1_k127_2554560_13 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001117 237.0
PYH1_k127_2554560_14 COGs COG1569 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000000000000002876 167.0
PYH1_k127_2554560_15 - - - - 0.0000000000000000000000000000000000001576 147.0
PYH1_k127_2554560_16 PFAM SpoVT AbrB - - - 0.000000000000000000000000000006833 120.0
PYH1_k127_2554560_17 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000000008444 102.0
PYH1_k127_2554560_2 formate dehydrogenase K00123 - 1.17.1.9 9.534e-258 799.0
PYH1_k127_2554560_3 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 3.411e-229 719.0
PYH1_k127_2554560_4 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 559.0
PYH1_k127_2554560_5 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 511.0
PYH1_k127_2554560_6 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
PYH1_k127_2554560_7 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
PYH1_k127_2554560_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 373.0
PYH1_k127_2554560_9 Amino-transferase class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
PYH1_k127_2598856_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.037e-235 738.0
PYH1_k127_2598856_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 522.0
PYH1_k127_2598856_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 469.0
PYH1_k127_2598856_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 307.0
PYH1_k127_2598856_4 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004439 274.0
PYH1_k127_2598856_5 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008576 254.0
PYH1_k127_2598856_6 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
PYH1_k127_2598856_7 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000105 200.0
PYH1_k127_2598856_8 Endoribonuclease L-PSP K10013 - - 0.0000000000000000000000000000000000000000000000004106 180.0
PYH1_k127_2598856_9 UPF0126 domain - - - 0.0000000489 56.0
PYH1_k127_2613525_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.271e-233 732.0
PYH1_k127_2613525_1 ribonuclease, Rne Rng family K08301 - - 1.403e-227 713.0
PYH1_k127_2613525_10 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000004261 222.0
PYH1_k127_2613525_11 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000006767 214.0
PYH1_k127_2613525_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000008867 182.0
PYH1_k127_2613525_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000002523 181.0
PYH1_k127_2613525_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000009126 133.0
PYH1_k127_2613525_15 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000002897 49.0
PYH1_k127_2613525_16 O-Antigen ligase - - - 0.000004199 50.0
PYH1_k127_2613525_2 Belongs to the GARS family K01945 - 6.3.4.13 1.192e-201 638.0
PYH1_k127_2613525_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 571.0
PYH1_k127_2613525_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 504.0
PYH1_k127_2613525_5 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 482.0
PYH1_k127_2613525_6 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 404.0
PYH1_k127_2613525_7 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 343.0
PYH1_k127_2613525_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 322.0
PYH1_k127_2613525_9 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 321.0
PYH1_k127_264225_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 571.0
PYH1_k127_264225_1 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000000000000000002401 145.0
PYH1_k127_264225_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000002851 108.0
PYH1_k127_264577_0 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 5.188e-216 680.0
PYH1_k127_264577_1 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 402.0
PYH1_k127_264577_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000004445 240.0
PYH1_k127_264577_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000001728 156.0
PYH1_k127_264577_4 - - - - 0.000000000000000000000001106 106.0
PYH1_k127_2671853_0 SNARE associated Golgi protein - - - 2.708e-317 987.0
PYH1_k127_2671853_1 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 539.0
PYH1_k127_2671853_10 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
PYH1_k127_2671853_11 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
PYH1_k127_2671853_12 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
PYH1_k127_2671853_13 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000004678 171.0
PYH1_k127_2671853_15 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000003047 140.0
PYH1_k127_2671853_16 YHS domain protein - - - 0.000000000000000000000000000000000004803 144.0
PYH1_k127_2671853_17 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000001516 139.0
PYH1_k127_2671853_18 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000004413 124.0
PYH1_k127_2671853_19 Transmembrane anti-sigma factor - - - 0.00002591 50.0
PYH1_k127_2671853_2 glutaminyl-tRNA K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 505.0
PYH1_k127_2671853_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
PYH1_k127_2671853_4 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
PYH1_k127_2671853_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 357.0
PYH1_k127_2671853_6 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 321.0
PYH1_k127_2671853_7 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
PYH1_k127_2671853_8 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005388 256.0
PYH1_k127_2671853_9 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005822 247.0
PYH1_k127_270463_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 2.773e-276 861.0
PYH1_k127_270463_1 phenylacetic acid degradation protein paaN - - - 7.194e-258 806.0
PYH1_k127_270463_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 465.0
PYH1_k127_270463_11 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 409.0
PYH1_k127_270463_12 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 395.0
PYH1_k127_270463_13 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 380.0
PYH1_k127_270463_14 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
PYH1_k127_270463_15 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 369.0
PYH1_k127_270463_16 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 364.0
PYH1_k127_270463_17 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 367.0
PYH1_k127_270463_18 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
PYH1_k127_270463_19 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 291.0
PYH1_k127_270463_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 3.631e-214 673.0
PYH1_k127_270463_20 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 285.0
PYH1_k127_270463_21 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 281.0
PYH1_k127_270463_22 O-Methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001182 271.0
PYH1_k127_270463_23 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004563 263.0
PYH1_k127_270463_24 lipopolysaccharide heptosyltransferase I K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007138 266.0
PYH1_k127_270463_25 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
PYH1_k127_270463_26 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000000000000000000000000000002174 224.0
PYH1_k127_270463_27 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
PYH1_k127_270463_28 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.00000000000000000000000000000000000000000000000000002925 190.0
PYH1_k127_270463_29 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000000000000004114 178.0
PYH1_k127_270463_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.172e-212 668.0
PYH1_k127_270463_30 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000001051 148.0
PYH1_k127_270463_31 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000003997 115.0
PYH1_k127_270463_32 - - - - 0.000000000000000001242 88.0
PYH1_k127_270463_33 Histidine kinase - - - 0.0000003106 59.0
PYH1_k127_270463_4 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 584.0
PYH1_k127_270463_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 596.0
PYH1_k127_270463_6 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 585.0
PYH1_k127_270463_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 566.0
PYH1_k127_270463_8 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 506.0
PYH1_k127_270463_9 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 472.0
PYH1_k127_2705127_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5.641e-289 908.0
PYH1_k127_2705127_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.518e-231 730.0
PYH1_k127_2705127_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 453.0
PYH1_k127_2705127_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 441.0
PYH1_k127_2705127_12 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 432.0
PYH1_k127_2705127_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 387.0
PYH1_k127_2705127_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 377.0
PYH1_k127_2705127_15 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 366.0
PYH1_k127_2705127_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
PYH1_k127_2705127_17 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
PYH1_k127_2705127_18 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 333.0
PYH1_k127_2705127_19 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 305.0
PYH1_k127_2705127_2 type IV pilus secretin PilQ K02666 - - 1.108e-230 739.0
PYH1_k127_2705127_20 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 293.0
PYH1_k127_2705127_21 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
PYH1_k127_2705127_22 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
PYH1_k127_2705127_23 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
PYH1_k127_2705127_24 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
PYH1_k127_2705127_25 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005549 244.0
PYH1_k127_2705127_26 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000007582 230.0
PYH1_k127_2705127_27 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
PYH1_k127_2705127_28 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
PYH1_k127_2705127_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003222 224.0
PYH1_k127_2705127_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 540.0
PYH1_k127_2705127_30 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
PYH1_k127_2705127_31 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000003528 213.0
PYH1_k127_2705127_32 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000001489 208.0
PYH1_k127_2705127_33 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000002003 198.0
PYH1_k127_2705127_34 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000001357 192.0
PYH1_k127_2705127_35 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000002329 191.0
PYH1_k127_2705127_36 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000003706 197.0
PYH1_k127_2705127_37 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000007204 184.0
PYH1_k127_2705127_38 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000003533 181.0
PYH1_k127_2705127_39 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000007431 169.0
PYH1_k127_2705127_4 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 537.0
PYH1_k127_2705127_40 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001503 166.0
PYH1_k127_2705127_41 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000007947 167.0
PYH1_k127_2705127_42 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000001482 166.0
PYH1_k127_2705127_43 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003194 150.0
PYH1_k127_2705127_44 Redoxin domain protein - - - 0.000000000000000000000000000000000000003042 153.0
PYH1_k127_2705127_45 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000006185 147.0
PYH1_k127_2705127_46 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000004856 145.0
PYH1_k127_2705127_47 S4 RNA-binding domain - - - 0.0000000000000000000000000000000000009591 144.0
PYH1_k127_2705127_48 Belongs to the frataxin family K06202 - - 0.0000000000000000000000000000000004626 133.0
PYH1_k127_2705127_49 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000008779 131.0
PYH1_k127_2705127_5 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 528.0
PYH1_k127_2705127_50 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000006508 130.0
PYH1_k127_2705127_51 Large extracellular alpha-helical protein - - - 0.00000000000000000003073 106.0
PYH1_k127_2705127_52 Ribosomal protein L30 K02907 - - 0.00000000000000000009195 90.0
PYH1_k127_2705127_53 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000001755 83.0
PYH1_k127_2705127_54 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002176 73.0
PYH1_k127_2705127_55 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002828 72.0
PYH1_k127_2705127_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 527.0
PYH1_k127_2705127_7 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 467.0
PYH1_k127_2705127_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
PYH1_k127_2705127_9 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 456.0
PYH1_k127_27520_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 519.0
PYH1_k127_27520_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 351.0
PYH1_k127_27520_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 342.0
PYH1_k127_27520_3 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000001094 260.0
PYH1_k127_27520_4 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
PYH1_k127_27520_5 AsmA family - - - 0.0000000000000000000000000000000000000000000000000007949 200.0
PYH1_k127_27520_6 - - - - 0.00000000000000000000000000000000000000000003499 176.0
PYH1_k127_2797097_0 Peptidase family M3 K01414 - 3.4.24.70 5.331e-281 887.0
PYH1_k127_2797097_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 1.448e-268 835.0
PYH1_k127_2797097_2 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 446.0
PYH1_k127_2797097_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 383.0
PYH1_k127_2797097_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 361.0
PYH1_k127_2797097_5 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000007219 141.0
PYH1_k127_2832779_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 378.0
PYH1_k127_2832779_1 COG3666 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
PYH1_k127_2832779_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0000000000000000000008817 98.0
PYH1_k127_2832779_3 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000004931 75.0
PYH1_k127_2832779_4 Protein involved in outer membrane biogenesis K01176,K21429 - 3.2.1.1 0.0001752 49.0
PYH1_k127_2858183_0 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
PYH1_k127_2858183_1 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000000000000000000000000000004601 221.0
PYH1_k127_2858183_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000001003 195.0
PYH1_k127_2858183_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000009508 179.0
PYH1_k127_2858183_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000001627 179.0
PYH1_k127_2858183_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000006695 179.0
PYH1_k127_2858183_6 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000002043 161.0
PYH1_k127_2858183_7 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000001466 141.0
PYH1_k127_2858183_8 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.00000000000000000000005942 103.0
PYH1_k127_2858183_9 Peptidase propeptide and YPEB domain - - - 0.00000000003364 69.0
PYH1_k127_288357_0 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 1.505e-241 758.0
PYH1_k127_288357_1 nucleotidyltransferase activity - - - 0.000000000000000000000000000000006487 140.0
PYH1_k127_288357_2 - - - - 0.0000000000000000000000071 106.0
PYH1_k127_288357_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000007062 65.0
PYH1_k127_2890996_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1110.0
PYH1_k127_2890996_1 GTP-binding protein K06207 - - 0.0 1018.0
PYH1_k127_2890996_10 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000103 171.0
PYH1_k127_2890996_11 Protein of unknown function (DUF2788) - - - 0.00000000000000000000001061 103.0
PYH1_k127_2890996_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000002452 51.0
PYH1_k127_2890996_2 Participates in both transcription termination and antitermination K02600 - - 5.116e-212 669.0
PYH1_k127_2890996_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 365.0
PYH1_k127_2890996_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
PYH1_k127_2890996_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000226 290.0
PYH1_k127_2890996_6 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002674 289.0
PYH1_k127_2890996_7 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
PYH1_k127_2890996_8 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000003346 217.0
PYH1_k127_2890996_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000002619 164.0
PYH1_k127_2894964_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 9.112e-309 972.0
PYH1_k127_2894964_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 604.0
PYH1_k127_2894964_10 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001527 246.0
PYH1_k127_2894964_11 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000003514 195.0
PYH1_k127_2894964_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000005765 186.0
PYH1_k127_2894964_13 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000001801 93.0
PYH1_k127_2894964_2 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 587.0
PYH1_k127_2894964_3 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 565.0
PYH1_k127_2894964_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 478.0
PYH1_k127_2894964_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 469.0
PYH1_k127_2894964_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 396.0
PYH1_k127_2894964_7 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 384.0
PYH1_k127_2894964_8 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
PYH1_k127_2894964_9 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008235 263.0
PYH1_k127_2903605_0 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 289.0
PYH1_k127_2903605_1 - - - - 0.0000000000000000000000000000000000000000000000000001131 198.0
PYH1_k127_2903605_2 - - - - 0.0000000000000000000006686 109.0
PYH1_k127_2927135_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.694e-214 670.0
PYH1_k127_2927135_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000002067 144.0
PYH1_k127_2933634_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.777e-284 901.0
PYH1_k127_2933634_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 529.0
PYH1_k127_2933634_10 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000002526 155.0
PYH1_k127_2933634_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001617 143.0
PYH1_k127_2933634_12 peptidyl-prolyl K03775 - 5.2.1.8 0.00000000000000000000000000000000003095 141.0
PYH1_k127_2933634_13 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000002236 72.0
PYH1_k127_2933634_14 - - - - 0.00000000498 65.0
PYH1_k127_2933634_2 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 389.0
PYH1_k127_2933634_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
PYH1_k127_2933634_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 372.0
PYH1_k127_2933634_5 Sugar kinases ribokinase family K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 349.0
PYH1_k127_2933634_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000154 274.0
PYH1_k127_2933634_7 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000036 250.0
PYH1_k127_2933634_8 SpoU rRNA Methylase family K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000001368 229.0
PYH1_k127_2933634_9 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000002016 224.0
PYH1_k127_2943501_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2516.0
PYH1_k127_2943501_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.2e-256 796.0
PYH1_k127_2943501_2 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
PYH1_k127_2943501_3 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000000000000000000000000000000000004964 177.0
PYH1_k127_2943501_4 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000001801 147.0
PYH1_k127_2951089_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.319e-247 786.0
PYH1_k127_2951089_1 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000001471 164.0
PYH1_k127_2951089_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000005174 134.0
PYH1_k127_296902_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1583.0
PYH1_k127_296902_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1004.0
PYH1_k127_296902_10 CRS1_YhbY K07574 - - 0.00000000000000000000000000000002401 130.0
PYH1_k127_296902_11 PFAM EAL domain - - - 0.00000000000000000000000000003291 134.0
PYH1_k127_296902_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.321e-195 619.0
PYH1_k127_296902_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 505.0
PYH1_k127_296902_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 482.0
PYH1_k127_296902_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 411.0
PYH1_k127_296902_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 321.0
PYH1_k127_296902_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 318.0
PYH1_k127_296902_8 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 287.0
PYH1_k127_296902_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 232.0
PYH1_k127_3022104_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0 1032.0
PYH1_k127_3022104_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 4.824e-314 972.0
PYH1_k127_3022104_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001427 238.0
PYH1_k127_3022104_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000001242 227.0
PYH1_k127_3022104_12 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000002571 230.0
PYH1_k127_3022104_13 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000006241 218.0
PYH1_k127_3022104_14 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000006532 210.0
PYH1_k127_3022104_15 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000007624 158.0
PYH1_k127_3022104_16 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000005574 58.0
PYH1_k127_3022104_2 heat shock protein binding - - - 1.487e-265 833.0
PYH1_k127_3022104_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 6.19e-243 771.0
PYH1_k127_3022104_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 580.0
PYH1_k127_3022104_5 Decaheme c-type cytochrome, DmsE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 430.0
PYH1_k127_3022104_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 364.0
PYH1_k127_3022104_7 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 301.0
PYH1_k127_3022104_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
PYH1_k127_3022104_9 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003644 241.0
PYH1_k127_3028380_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1007.0
PYH1_k127_3028380_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5e-324 998.0
PYH1_k127_3028380_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 542.0
PYH1_k127_3028380_11 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 520.0
PYH1_k127_3028380_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 447.0
PYH1_k127_3028380_13 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 447.0
PYH1_k127_3028380_14 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 413.0
PYH1_k127_3028380_15 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 406.0
PYH1_k127_3028380_16 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 400.0
PYH1_k127_3028380_17 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 391.0
PYH1_k127_3028380_18 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 379.0
PYH1_k127_3028380_19 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 366.0
PYH1_k127_3028380_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.994e-286 905.0
PYH1_k127_3028380_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
PYH1_k127_3028380_21 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
PYH1_k127_3028380_22 Superoxide dismutase K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 344.0
PYH1_k127_3028380_23 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 341.0
PYH1_k127_3028380_24 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
PYH1_k127_3028380_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 309.0
PYH1_k127_3028380_26 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002273 278.0
PYH1_k127_3028380_27 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001212 278.0
PYH1_k127_3028380_28 negative regulator of sigma E activity K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007043 272.0
PYH1_k127_3028380_29 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009977 258.0
PYH1_k127_3028380_3 Belongs to the malate synthase family K01638 - 2.3.3.9 4.877e-281 870.0
PYH1_k127_3028380_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000001377 254.0
PYH1_k127_3028380_31 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
PYH1_k127_3028380_32 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
PYH1_k127_3028380_33 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000003614 217.0
PYH1_k127_3028380_34 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000006172 207.0
PYH1_k127_3028380_35 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000005226 184.0
PYH1_k127_3028380_36 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000002909 160.0
PYH1_k127_3028380_37 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000009052 160.0
PYH1_k127_3028380_38 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000001299 156.0
PYH1_k127_3028380_39 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000001689 153.0
PYH1_k127_3028380_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.884e-247 776.0
PYH1_k127_3028380_40 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000117 153.0
PYH1_k127_3028380_41 Tautomerase enzyme - - - 0.0000000000000000000000000000000000003113 146.0
PYH1_k127_3028380_42 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000003012 132.0
PYH1_k127_3028380_43 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000005035 112.0
PYH1_k127_3028380_44 Domain of unknown function (DUF4845) - - - 0.00000000000000000000429 97.0
PYH1_k127_3028380_45 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000001078 89.0
PYH1_k127_3028380_46 - - - - 0.0000000001824 64.0
PYH1_k127_3028380_48 Anti sigma-E protein RseA K03597 - - 0.0000000007514 67.0
PYH1_k127_3028380_49 Belongs to the 'phage' integrase family - - - 0.000000003965 63.0
PYH1_k127_3028380_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.613e-214 674.0
PYH1_k127_3028380_50 - - - - 0.0000009923 55.0
PYH1_k127_3028380_51 protein related to plant photosystem II stability assembly factor - - - 0.0000107 55.0
PYH1_k127_3028380_52 Acetyltransferase (GNAT) domain - - - 0.0004646 47.0
PYH1_k127_3028380_53 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0005208 49.0
PYH1_k127_3028380_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.665e-210 659.0
PYH1_k127_3028380_7 Chromate K07240 - - 1.384e-204 646.0
PYH1_k127_3028380_8 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 584.0
PYH1_k127_3028380_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 556.0
PYH1_k127_3107244_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 561.0
PYH1_k127_3107244_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 417.0
PYH1_k127_3107244_2 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000005938 194.0
PYH1_k127_3157735_0 type II secretion system protein E K02454 - - 2.226e-208 657.0
PYH1_k127_3157735_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 2.665e-203 639.0
PYH1_k127_3157735_10 Type II secretion system (T2SS), protein N K02463 - - 0.0000000000000000000000000000000441 135.0
PYH1_k127_3157735_11 general secretion pathway protein K02457 - - 0.00000000000000000000000253 108.0
PYH1_k127_3157735_12 General secretion pathway K02462 - - 0.0000000000000000009169 92.0
PYH1_k127_3157735_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000965 86.0
PYH1_k127_3157735_14 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000001364 93.0
PYH1_k127_3157735_15 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000003196 93.0
PYH1_k127_3157735_16 General secretion pathway protein L K02461 - - 0.00000000000000006133 94.0
PYH1_k127_3157735_17 general secretion pathway protein K02452 - - 0.000000000002887 76.0
PYH1_k127_3157735_18 helix_turn_helix ASNC type K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000005184 71.0
PYH1_k127_3157735_2 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 617.0
PYH1_k127_3157735_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 512.0
PYH1_k127_3157735_4 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 430.0
PYH1_k127_3157735_5 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
PYH1_k127_3157735_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 301.0
PYH1_k127_3157735_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001797 238.0
PYH1_k127_3157735_8 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
PYH1_k127_3157735_9 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001676 201.0
PYH1_k127_3209195_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 385.0
PYH1_k127_3209195_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000003372 231.0
PYH1_k127_3209195_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000002444 222.0
PYH1_k127_3209195_3 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000001959 180.0
PYH1_k127_3209195_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000004056 168.0
PYH1_k127_3209195_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000007687 177.0
PYH1_k127_3209195_6 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000001297 131.0
PYH1_k127_3209195_7 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000006856 111.0
PYH1_k127_3209195_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000118 59.0
PYH1_k127_3221545_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1252.0
PYH1_k127_3221545_1 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 5.523e-195 621.0
PYH1_k127_3221545_10 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000006072 238.0
PYH1_k127_3221545_11 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000004406 193.0
PYH1_k127_3221545_12 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000007643 167.0
PYH1_k127_3221545_2 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 606.0
PYH1_k127_3221545_3 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 518.0
PYH1_k127_3221545_4 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 407.0
PYH1_k127_3221545_5 Quinohemoprotein amine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 399.0
PYH1_k127_3221545_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 331.0
PYH1_k127_3221545_7 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000002597 269.0
PYH1_k127_3221545_8 peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002378 258.0
PYH1_k127_3221545_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003639 243.0
PYH1_k127_3233814_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1430.0
PYH1_k127_3233814_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.167e-244 773.0
PYH1_k127_3233814_10 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 420.0
PYH1_k127_3233814_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 418.0
PYH1_k127_3233814_12 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
PYH1_k127_3233814_13 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 384.0
PYH1_k127_3233814_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 381.0
PYH1_k127_3233814_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 379.0
PYH1_k127_3233814_16 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 342.0
PYH1_k127_3233814_17 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
PYH1_k127_3233814_18 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 313.0
PYH1_k127_3233814_19 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 294.0
PYH1_k127_3233814_2 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 608.0
PYH1_k127_3233814_20 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002213 285.0
PYH1_k127_3233814_21 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
PYH1_k127_3233814_22 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
PYH1_k127_3233814_23 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001628 269.0
PYH1_k127_3233814_24 ABC transporter permease K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
PYH1_k127_3233814_25 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002068 256.0
PYH1_k127_3233814_26 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
PYH1_k127_3233814_27 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
PYH1_k127_3233814_28 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
PYH1_k127_3233814_29 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
PYH1_k127_3233814_3 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 606.0
PYH1_k127_3233814_30 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000001455 221.0
PYH1_k127_3233814_31 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
PYH1_k127_3233814_32 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000006287 198.0
PYH1_k127_3233814_33 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000003735 192.0
PYH1_k127_3233814_34 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000001466 151.0
PYH1_k127_3233814_35 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000001689 145.0
PYH1_k127_3233814_36 sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000006646 133.0
PYH1_k127_3233814_37 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000000003639 136.0
PYH1_k127_3233814_38 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000003483 124.0
PYH1_k127_3233814_39 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000008091 131.0
PYH1_k127_3233814_4 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 593.0
PYH1_k127_3233814_40 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000001765 116.0
PYH1_k127_3233814_41 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000006275 95.0
PYH1_k127_3233814_42 PFAM PsiF repeat protein - - - 0.00000000006757 65.0
PYH1_k127_3233814_43 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000002264 57.0
PYH1_k127_3233814_44 Tetratricopeptide repeat - - - 0.000005176 59.0
PYH1_k127_3233814_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 580.0
PYH1_k127_3233814_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 545.0
PYH1_k127_3233814_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 523.0
PYH1_k127_3233814_8 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 520.0
PYH1_k127_3233814_9 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 503.0
PYH1_k127_32724_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 1.373e-308 957.0
PYH1_k127_32724_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.042e-216 686.0
PYH1_k127_32724_2 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 374.0
PYH1_k127_32724_3 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001689 247.0
PYH1_k127_32724_4 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000418 230.0
PYH1_k127_32724_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001664 138.0
PYH1_k127_32724_6 toxin-antitoxin pair type II binding - - - 0.000000000000000126 82.0
PYH1_k127_32724_7 trans-aconitate 2-methyltransferase activity K00563,K02169,K16868 - 2.1.1.187,2.1.1.197,2.1.1.265 0.000000000000001503 89.0
PYH1_k127_3297118_0 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 302.0
PYH1_k127_3297118_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000008406 123.0
PYH1_k127_3297118_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000006648 109.0
PYH1_k127_3297118_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000005872 107.0
PYH1_k127_3311998_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 3.306e-202 636.0
PYH1_k127_3311998_1 Aamy_C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
PYH1_k127_3337694_0 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000008017 201.0
PYH1_k127_3337694_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000001076 155.0
PYH1_k127_3337694_2 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000006104 146.0
PYH1_k127_3337694_3 peptidase - - - 0.000000000000000000000000000002643 121.0
PYH1_k127_3337694_4 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000000001046 115.0
PYH1_k127_334320_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
PYH1_k127_334320_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH1_k127_334320_2 Citrate transporter - - - 0.00000000000000001758 87.0
PYH1_k127_334770_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000005741 220.0
PYH1_k127_3363712_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 6.942e-199 635.0
PYH1_k127_3363712_1 CoA-transferase family III K07749 - 2.8.3.16 2.66e-197 629.0
PYH1_k127_3363712_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001668 266.0
PYH1_k127_3363712_11 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000005766 216.0
PYH1_k127_3363712_12 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001104 222.0
PYH1_k127_3363712_13 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000005136 206.0
PYH1_k127_3363712_14 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000117 202.0
PYH1_k127_3363712_15 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000003904 183.0
PYH1_k127_3363712_16 MAPEG family - - - 0.00000000000000000000000000000000002661 139.0
PYH1_k127_3363712_17 competence protein - - - 0.00000000000000000000000000000006209 140.0
PYH1_k127_3363712_18 PFAM porin Gram-negative type - - - 0.000000000000000000000008295 113.0
PYH1_k127_3363712_2 binding-protein-dependent transport systems inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 605.0
PYH1_k127_3363712_3 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 578.0
PYH1_k127_3363712_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 579.0
PYH1_k127_3363712_5 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 504.0
PYH1_k127_3363712_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 480.0
PYH1_k127_3363712_7 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 459.0
PYH1_k127_3363712_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 370.0
PYH1_k127_3363712_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006153 288.0
PYH1_k127_3372245_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 597.0
PYH1_k127_3378275_0 Subtilase family - - - 1.014e-254 806.0
PYH1_k127_3378275_1 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.224e-232 732.0
PYH1_k127_3378275_10 mRNA binding K07339 - - 0.00000000000000002099 81.0
PYH1_k127_3378275_11 positive regulation of growth - - - 0.00000000000002105 75.0
PYH1_k127_3378275_13 GGDEF domain - - - 0.000009181 51.0
PYH1_k127_3378275_2 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 473.0
PYH1_k127_3378275_3 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 325.0
PYH1_k127_3378275_4 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
PYH1_k127_3378275_5 Protein of unknown function, DUF480 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 264.0
PYH1_k127_3378275_6 PIN domain - - - 0.00000000000000000000000000000000000000000009692 162.0
PYH1_k127_3378275_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000002446 118.0
PYH1_k127_3378275_8 Histidine kinase K13246 - 3.1.4.52 0.00000000000000000000000002985 127.0
PYH1_k127_3378275_9 - - - - 0.00000000000000000236 89.0
PYH1_k127_3389194_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1398.0
PYH1_k127_3389194_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1384.0
PYH1_k127_3389194_10 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 472.0
PYH1_k127_3389194_11 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 425.0
PYH1_k127_3389194_12 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
PYH1_k127_3389194_13 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 394.0
PYH1_k127_3389194_14 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 369.0
PYH1_k127_3389194_15 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 298.0
PYH1_k127_3389194_16 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000003631 211.0
PYH1_k127_3389194_17 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
PYH1_k127_3389194_18 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000005533 188.0
PYH1_k127_3389194_19 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000223 166.0
PYH1_k127_3389194_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.441e-314 969.0
PYH1_k127_3389194_20 - - - - 0.0000000000000000000000000000000005089 143.0
PYH1_k127_3389194_21 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000001983 121.0
PYH1_k127_3389194_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 3.747e-305 947.0
PYH1_k127_3389194_4 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 4.589e-286 891.0
PYH1_k127_3389194_5 CoA-transferase family III - - - 2.583e-210 665.0
PYH1_k127_3389194_6 COG1960 Acyl-CoA dehydrogenases - - - 6.044e-199 625.0
PYH1_k127_3389194_7 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 572.0
PYH1_k127_3389194_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 498.0
PYH1_k127_3389194_9 branched-chain amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 477.0
PYH1_k127_3412994_0 CoA binding domain K09181 - - 0.0 1053.0
PYH1_k127_3412994_1 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 1.285e-311 990.0
PYH1_k127_3412994_10 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 393.0
PYH1_k127_3412994_11 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 379.0
PYH1_k127_3412994_12 Membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
PYH1_k127_3412994_13 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
PYH1_k127_3412994_14 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 321.0
PYH1_k127_3412994_15 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 314.0
PYH1_k127_3412994_16 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
PYH1_k127_3412994_17 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000206 269.0
PYH1_k127_3412994_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
PYH1_k127_3412994_19 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000003181 221.0
PYH1_k127_3412994_2 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 2.23e-273 864.0
PYH1_k127_3412994_20 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000006004 229.0
PYH1_k127_3412994_21 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
PYH1_k127_3412994_22 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000000006709 214.0
PYH1_k127_3412994_23 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000001134 191.0
PYH1_k127_3412994_24 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000002978 190.0
PYH1_k127_3412994_25 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000918 171.0
PYH1_k127_3412994_26 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000009249 171.0
PYH1_k127_3412994_27 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.000000000000000000000000000000000002377 150.0
PYH1_k127_3412994_28 Permease MlaE K02066 - - 0.0000000000000000000000000000008684 123.0
PYH1_k127_3412994_29 Multisubunit Na H antiporter, MnhG subunit K05564,K05571 - - 0.000000000000000000000000000008863 126.0
PYH1_k127_3412994_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 4.317e-234 734.0
PYH1_k127_3412994_30 PFAM multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000000001262 105.0
PYH1_k127_3412994_31 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000961 71.0
PYH1_k127_3412994_32 - - - - 0.0000000000001419 78.0
PYH1_k127_3412994_33 Protein of unknown function (DUF2934) - - - 0.0000003215 55.0
PYH1_k127_3412994_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.719e-222 699.0
PYH1_k127_3412994_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 528.0
PYH1_k127_3412994_6 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 462.0
PYH1_k127_3412994_7 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 467.0
PYH1_k127_3412994_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 444.0
PYH1_k127_3412994_9 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 433.0
PYH1_k127_3431701_0 Glycosyl transferase 4-like domain K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 289.0
PYH1_k127_3431701_1 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000004306 191.0
PYH1_k127_3453435_0 Dehydratase family K13875 - 4.2.1.25 1.038e-302 935.0
PYH1_k127_3453435_1 amine dehydrogenase activity - - - 5.873e-297 941.0
PYH1_k127_3453435_10 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000005024 114.0
PYH1_k127_3453435_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000008928 121.0
PYH1_k127_3453435_12 Helix-turn-helix domain - - - 0.00000000000000000000000001732 111.0
PYH1_k127_3453435_14 Zinc finger, swim domain protein - - - 0.0000000008996 67.0
PYH1_k127_3453435_2 Bacterial extracellular solute-binding protein K02027 - - 4.92e-216 677.0
PYH1_k127_3453435_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
PYH1_k127_3453435_4 ABC-type sugar K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 445.0
PYH1_k127_3453435_5 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 441.0
PYH1_k127_3453435_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 431.0
PYH1_k127_3453435_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
PYH1_k127_3453435_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000001473 177.0
PYH1_k127_3453435_9 Protease prsW family - - - 0.000000000000000000000000000000000000001567 160.0
PYH1_k127_3455712_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1309.0
PYH1_k127_3455712_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1283.0
PYH1_k127_3455712_10 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 499.0
PYH1_k127_3455712_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 417.0
PYH1_k127_3455712_12 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 393.0
PYH1_k127_3455712_13 Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
PYH1_k127_3455712_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 358.0
PYH1_k127_3455712_15 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 335.0
PYH1_k127_3455712_16 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 331.0
PYH1_k127_3455712_17 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
PYH1_k127_3455712_18 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002091 273.0
PYH1_k127_3455712_19 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
PYH1_k127_3455712_2 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.25e-321 991.0
PYH1_k127_3455712_20 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
PYH1_k127_3455712_21 NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000005548 223.0
PYH1_k127_3455712_22 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
PYH1_k127_3455712_23 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000002546 187.0
PYH1_k127_3455712_24 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000818 178.0
PYH1_k127_3455712_25 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000006747 175.0
PYH1_k127_3455712_26 Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000117 171.0
PYH1_k127_3455712_27 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000000004454 168.0
PYH1_k127_3455712_28 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000009195 174.0
PYH1_k127_3455712_29 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000006932 166.0
PYH1_k127_3455712_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.317e-268 831.0
PYH1_k127_3455712_30 - - - - 0.000000000000000000000000000000000000000002177 159.0
PYH1_k127_3455712_31 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000001696 152.0
PYH1_k127_3455712_32 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000134 140.0
PYH1_k127_3455712_33 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000001016 124.0
PYH1_k127_3455712_34 - - - - 0.000000000000000000000000001374 115.0
PYH1_k127_3455712_35 FixH family K09926 - - 0.000000000000000000000000007601 117.0
PYH1_k127_3455712_36 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000726 110.0
PYH1_k127_3455712_37 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000005397 98.0
PYH1_k127_3455712_38 cellulase activity - - - 0.00000000000000000003907 105.0
PYH1_k127_3455712_39 Cbb3-type cytochrome oxidase K00407 - - 0.000000000000002591 76.0
PYH1_k127_3455712_4 Tripartite tricarboxylate transporter TctA family K07793 - - 1.982e-244 762.0
PYH1_k127_3455712_40 cytochrome oxidase maturation protein cbb3-type - - - 0.000000008964 59.0
PYH1_k127_3455712_41 Protein of unknown function (DUF1223) - - - 0.00006198 49.0
PYH1_k127_3455712_5 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 1.095e-219 694.0
PYH1_k127_3455712_6 Domain of unknown function (DUF5117) - - - 3.634e-210 687.0
PYH1_k127_3455712_7 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 593.0
PYH1_k127_3455712_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 586.0
PYH1_k127_3455712_9 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 585.0
PYH1_k127_3483086_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1711.0
PYH1_k127_3483086_1 Tetratricopeptide repeat - - - 0.0 1206.0
PYH1_k127_3483086_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 582.0
PYH1_k127_3483086_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 572.0
PYH1_k127_3483086_12 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 516.0
PYH1_k127_3483086_13 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 501.0
PYH1_k127_3483086_14 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 471.0
PYH1_k127_3483086_15 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 456.0
PYH1_k127_3483086_16 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 460.0
PYH1_k127_3483086_17 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 433.0
PYH1_k127_3483086_18 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 412.0
PYH1_k127_3483086_19 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 368.0
PYH1_k127_3483086_2 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.317e-288 902.0
PYH1_k127_3483086_20 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
PYH1_k127_3483086_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 356.0
PYH1_k127_3483086_22 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 355.0
PYH1_k127_3483086_23 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
PYH1_k127_3483086_24 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 335.0
PYH1_k127_3483086_25 hydrolase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 333.0
PYH1_k127_3483086_26 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 323.0
PYH1_k127_3483086_27 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
PYH1_k127_3483086_28 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 290.0
PYH1_k127_3483086_29 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 298.0
PYH1_k127_3483086_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.941e-251 783.0
PYH1_k127_3483086_30 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 296.0
PYH1_k127_3483086_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001314 277.0
PYH1_k127_3483086_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
PYH1_k127_3483086_33 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 267.0
PYH1_k127_3483086_34 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
PYH1_k127_3483086_35 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
PYH1_k127_3483086_36 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
PYH1_k127_3483086_37 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
PYH1_k127_3483086_38 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
PYH1_k127_3483086_39 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000001391 238.0
PYH1_k127_3483086_4 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 2.556e-240 759.0
PYH1_k127_3483086_40 FAD dependent oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000004746 238.0
PYH1_k127_3483086_41 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000208 238.0
PYH1_k127_3483086_42 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
PYH1_k127_3483086_43 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000008606 223.0
PYH1_k127_3483086_44 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000001988 227.0
PYH1_k127_3483086_45 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001287 220.0
PYH1_k127_3483086_46 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000008851 219.0
PYH1_k127_3483086_47 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000002162 204.0
PYH1_k127_3483086_48 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000006374 189.0
PYH1_k127_3483086_49 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000003358 179.0
PYH1_k127_3483086_5 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 2.019e-238 746.0
PYH1_k127_3483086_50 Dioxygenase K00449 - 1.13.11.3 0.00000000000000000000000000000000000000005635 161.0
PYH1_k127_3483086_51 LysM domain K08086 - - 0.00000000000000000000000000000000000006728 148.0
PYH1_k127_3483086_52 - - - - 0.0000000000000000000000000000003211 126.0
PYH1_k127_3483086_53 Entericidin EcnA/B family - - - 0.000000007859 57.0
PYH1_k127_3483086_54 ATPases associated with a variety of cellular activities K01996 - - 0.000009895 55.0
PYH1_k127_3483086_6 Tetratricopeptide repeat - - - 1.148e-234 743.0
PYH1_k127_3483086_7 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 1.447e-222 703.0
PYH1_k127_3483086_8 o-acetylhomoserine K01740 - 2.5.1.49 1.18e-217 681.0
PYH1_k127_3483086_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 594.0
PYH1_k127_3497214_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.817e-219 687.0
PYH1_k127_3497214_1 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 554.0
PYH1_k127_3497214_2 Dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 518.0
PYH1_k127_3497214_3 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
PYH1_k127_3497214_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 350.0
PYH1_k127_3497214_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 295.0
PYH1_k127_3497214_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000003185 235.0
PYH1_k127_3497214_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000008072 104.0
PYH1_k127_3497214_8 - - - - 0.000000000002126 70.0
PYH1_k127_3497214_9 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000007944 60.0
PYH1_k127_3497870_0 Ammonium Transporter Family K03320,K06580 - - 1.628e-218 685.0
PYH1_k127_3497870_1 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 586.0
PYH1_k127_3497870_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 503.0
PYH1_k127_3497870_3 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000001573 224.0
PYH1_k127_3497870_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000006036 130.0
PYH1_k127_3497870_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000001002 127.0
PYH1_k127_3497870_6 Cytochrome c K17223 - - 0.0000000000000000000000004644 111.0
PYH1_k127_3500569_0 AMP-binding enzyme K12508 - 6.2.1.34 2.303e-246 774.0
PYH1_k127_3500569_1 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 512.0
PYH1_k127_3500569_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 471.0
PYH1_k127_3500569_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 401.0
PYH1_k127_3500569_4 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 363.0
PYH1_k127_3500569_5 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000001014 189.0
PYH1_k127_3500569_6 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000001046 183.0
PYH1_k127_3500569_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.00000000001141 65.0
PYH1_k127_3509676_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.5e-323 1004.0
PYH1_k127_3509676_1 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 5.864e-314 967.0
PYH1_k127_3509676_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 587.0
PYH1_k127_3509676_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 549.0
PYH1_k127_3509676_12 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 494.0
PYH1_k127_3509676_13 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 484.0
PYH1_k127_3509676_14 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 473.0
PYH1_k127_3509676_15 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 428.0
PYH1_k127_3509676_16 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 394.0
PYH1_k127_3509676_17 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
PYH1_k127_3509676_18 transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 348.0
PYH1_k127_3509676_19 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 354.0
PYH1_k127_3509676_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 3.413e-313 971.0
PYH1_k127_3509676_20 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 340.0
PYH1_k127_3509676_21 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 334.0
PYH1_k127_3509676_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 313.0
PYH1_k127_3509676_23 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
PYH1_k127_3509676_24 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
PYH1_k127_3509676_25 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
PYH1_k127_3509676_26 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003892 219.0
PYH1_k127_3509676_27 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000003134 206.0
PYH1_k127_3509676_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000005754 159.0
PYH1_k127_3509676_29 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000008728 153.0
PYH1_k127_3509676_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 9.132e-300 928.0
PYH1_k127_3509676_30 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000005539 146.0
PYH1_k127_3509676_31 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000001437 135.0
PYH1_k127_3509676_32 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000001389 125.0
PYH1_k127_3509676_33 Protein of unknown function (DUF3024) - - - 0.00000000000000000000000000001947 121.0
PYH1_k127_3509676_34 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000004881 116.0
PYH1_k127_3509676_35 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000004275 108.0
PYH1_k127_3509676_36 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000101 74.0
PYH1_k127_3509676_37 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.00000000002475 65.0
PYH1_k127_3509676_38 - - - - 0.000000000181 70.0
PYH1_k127_3509676_4 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.921e-279 867.0
PYH1_k127_3509676_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.376e-265 829.0
PYH1_k127_3509676_6 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 8.014e-246 778.0
PYH1_k127_3509676_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.413e-241 748.0
PYH1_k127_3509676_8 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 1.898e-207 657.0
PYH1_k127_3509676_9 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 5.32e-204 649.0
PYH1_k127_3543752_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1e-323 994.0
PYH1_k127_3543752_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.119e-260 807.0
PYH1_k127_3554642_0 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 566.0
PYH1_k127_3554642_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 529.0
PYH1_k127_3554642_2 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 480.0
PYH1_k127_3554642_3 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 287.0
PYH1_k127_3554642_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000175 94.0
PYH1_k127_3574910_0 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 353.0
PYH1_k127_3574910_1 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000196 248.0
PYH1_k127_3574910_2 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
PYH1_k127_3574910_3 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000001182 190.0
PYH1_k127_3574910_4 oxidation protein K17227 - - 0.00000000000000000000000000000000000000003192 154.0
PYH1_k127_3574910_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000001199 111.0
PYH1_k127_3574910_6 Peptidase S24-like - - - 0.0000000000008283 71.0
PYH1_k127_3619878_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 590.0
PYH1_k127_3619878_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002321 274.0
PYH1_k127_3619878_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000004478 137.0
PYH1_k127_3619878_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000006383 103.0
PYH1_k127_3652292_0 5-oxoprolinase K01469 - 3.5.2.9 0.0 1338.0
PYH1_k127_3652292_1 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000001082 108.0
PYH1_k127_3691155_0 5-oxoprolinase K01469 - 3.5.2.9 6.151e-211 660.0
PYH1_k127_3691155_1 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000003782 232.0
PYH1_k127_3691155_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000002638 81.0
PYH1_k127_3718168_0 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 421.0
PYH1_k127_3718168_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 410.0
PYH1_k127_3718168_10 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000748 52.0
PYH1_k127_3718168_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 367.0
PYH1_k127_3718168_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000002338 197.0
PYH1_k127_3718168_4 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000001792 149.0
PYH1_k127_3718168_5 Plasmid stabilization system K19092 - - 0.00000000000000000000000000165 115.0
PYH1_k127_3718168_6 Phosphopantetheine attachment site - - - 0.00000000000000000003431 102.0
PYH1_k127_3718168_7 Cytochrome c - - - 0.00000006263 54.0
PYH1_k127_3718168_8 Cytochrome c - - - 0.0000005936 57.0
PYH1_k127_3718168_9 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000001378 53.0
PYH1_k127_3729810_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 538.0
PYH1_k127_3729810_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 507.0
PYH1_k127_3729810_10 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000004709 213.0
PYH1_k127_3729810_11 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000001371 179.0
PYH1_k127_3729810_12 GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001328 130.0
PYH1_k127_3729810_13 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000007517 114.0
PYH1_k127_3729810_14 Domain of unknown function (DUF1992) - - - 0.0000000000000000000009623 99.0
PYH1_k127_3729810_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 447.0
PYH1_k127_3729810_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 413.0
PYH1_k127_3729810_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 407.0
PYH1_k127_3729810_5 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 391.0
PYH1_k127_3729810_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
PYH1_k127_3729810_7 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
PYH1_k127_3729810_8 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 293.0
PYH1_k127_3729810_9 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 293.0
PYH1_k127_375667_0 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 494.0
PYH1_k127_375667_1 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 464.0
PYH1_k127_375667_2 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 293.0
PYH1_k127_375667_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000005952 221.0
PYH1_k127_3772892_0 FAD dependent oxidoreductase central domain - - - 0.0 1357.0
PYH1_k127_3772892_1 Peptidase M61 - - - 1.085e-213 679.0
PYH1_k127_3772892_2 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 513.0
PYH1_k127_3772892_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
PYH1_k127_3772892_4 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 417.0
PYH1_k127_3772892_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000004316 179.0
PYH1_k127_3772892_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000002138 168.0
PYH1_k127_3772892_7 COG0183 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000005149 114.0
PYH1_k127_3772892_8 - - - - 0.000000002655 66.0
PYH1_k127_3772892_9 Histone methylation protein DOT1 - - - 0.0000002405 55.0
PYH1_k127_38560_0 Penicillin amidase K01434 - 3.5.1.11 5.514e-320 1004.0
PYH1_k127_38560_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000004266 179.0
PYH1_k127_38560_2 DDE superfamily endonuclease K07494 - - 0.0001222 46.0
PYH1_k127_38562_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1257.0
PYH1_k127_38562_1 DNA helicase K03657 - 3.6.4.12 7.803e-282 902.0
PYH1_k127_38562_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
PYH1_k127_38562_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 333.0
PYH1_k127_38562_4 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000003749 201.0
PYH1_k127_38562_5 - - - - 0.000000000000000000000000000001341 126.0
PYH1_k127_38562_6 - - - - 0.00000000000000000000000000009869 125.0
PYH1_k127_38562_7 DDE superfamily endonuclease K07494 - - 0.00006446 47.0
PYH1_k127_3856836_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 9.026e-275 862.0
PYH1_k127_3856836_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 6.818e-246 773.0
PYH1_k127_3856836_2 viral genome integration into host DNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 430.0
PYH1_k127_3856836_3 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 396.0
PYH1_k127_3856836_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 343.0
PYH1_k127_3856836_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
PYH1_k127_3856836_6 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
PYH1_k127_3856836_7 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000003945 140.0
PYH1_k127_3856836_8 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000009349 136.0
PYH1_k127_387684_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 490.0
PYH1_k127_387684_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 457.0
PYH1_k127_3918474_0 Elements of external origin K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 441.0
PYH1_k127_3918474_1 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000006025 149.0
PYH1_k127_3918474_2 Transposase K07497 - - 0.0000000000000000000000000001437 117.0
PYH1_k127_3918474_3 Integrase core domain - - - 0.0000000008536 63.0
PYH1_k127_3921168_0 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007108 275.0
PYH1_k127_3921168_1 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
PYH1_k127_3921168_2 Cytochrome c - - - 0.000000000000000000000000000153 128.0
PYH1_k127_3970989_0 mechanosensitive ion channel K03442,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 419.0
PYH1_k127_3970989_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 320.0
PYH1_k127_4021091_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 439.0
PYH1_k127_4021091_1 COG3436 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
PYH1_k127_4021091_10 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000021 63.0
PYH1_k127_4021091_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000000000001714 162.0
PYH1_k127_4021091_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000104 126.0
PYH1_k127_4021091_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000002998 121.0
PYH1_k127_4021091_5 - - - - 0.000000000000000000000000002836 112.0
PYH1_k127_4021091_6 Protein of unknown function (DUF2283) - - - 0.000000000000000000000002838 104.0
PYH1_k127_4021091_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000481 102.0
PYH1_k127_4021091_8 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000002955 71.0
PYH1_k127_4021091_9 copG family - - - 0.0000000001697 65.0
PYH1_k127_4027940_0 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 572.0
PYH1_k127_4027940_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 481.0
PYH1_k127_4027940_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 368.0
PYH1_k127_4027940_3 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 351.0
PYH1_k127_4027940_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 340.0
PYH1_k127_4027940_5 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
PYH1_k127_4027940_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000006457 123.0
PYH1_k127_4027940_7 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000001242 88.0
PYH1_k127_4027940_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0002688 44.0
PYH1_k127_4042048_0 Evidence 2b Function of strongly homologous gene - - - 6.575e-234 732.0
PYH1_k127_4042048_1 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 419.0
PYH1_k127_4042048_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000005891 77.0
PYH1_k127_4079718_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 563.0
PYH1_k127_4079718_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 519.0
PYH1_k127_4079718_10 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000005685 154.0
PYH1_k127_4079718_11 Aminotransferase class-V - - - 0.0004335 46.0
PYH1_k127_4079718_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 435.0
PYH1_k127_4079718_3 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 349.0
PYH1_k127_4079718_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 348.0
PYH1_k127_4079718_5 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 334.0
PYH1_k127_4079718_6 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 299.0
PYH1_k127_4079718_7 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
PYH1_k127_4079718_8 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000001235 193.0
PYH1_k127_4079718_9 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000000228 195.0
PYH1_k127_4208102_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.043e-219 697.0
PYH1_k127_4208102_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 368.0
PYH1_k127_4208102_2 import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000001803 218.0
PYH1_k127_4208102_3 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000003634 137.0
PYH1_k127_42114_0 Sulfatase - - - 2.613e-264 822.0
PYH1_k127_42114_1 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 492.0
PYH1_k127_42114_2 PIN domain - - - 0.0000000000000000000000000000000000000000000001834 170.0
PYH1_k127_42114_3 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000004194 159.0
PYH1_k127_42114_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000002704 126.0
PYH1_k127_4214915_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 5.207e-242 756.0
PYH1_k127_4214915_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 467.0
PYH1_k127_4235598_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 1.428e-222 707.0
PYH1_k127_4235598_1 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 454.0
PYH1_k127_4235598_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
PYH1_k127_4253654_0 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 508.0
PYH1_k127_4253654_1 ABC transporter K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 464.0
PYH1_k127_4253654_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 452.0
PYH1_k127_4253654_3 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000001205 233.0
PYH1_k127_4253654_4 Transcriptional regulator K19333 - - 0.00000000000000000000000000000000000000001004 157.0
PYH1_k127_429395_0 Redoxin - - - 0.000000000000000000000000009349 110.0
PYH1_k127_429395_1 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000005178 119.0
PYH1_k127_429395_2 Bacterial transcriptional activator domain - - - 0.00000000004932 69.0
PYH1_k127_4296615_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.337e-309 968.0
PYH1_k127_4296615_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.374e-308 950.0
PYH1_k127_4296615_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000003772 235.0
PYH1_k127_4296615_11 Tetratricopeptide repeat K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000004207 238.0
PYH1_k127_4296615_12 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000004174 235.0
PYH1_k127_4296615_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
PYH1_k127_4296615_14 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000003401 180.0
PYH1_k127_4296615_15 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000001835 177.0
PYH1_k127_4296615_16 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000312 165.0
PYH1_k127_4296615_17 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000005623 126.0
PYH1_k127_4296615_18 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000003624 106.0
PYH1_k127_4296615_19 dehydrogenase - - - 0.00006767 49.0
PYH1_k127_4296615_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 566.0
PYH1_k127_4296615_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 559.0
PYH1_k127_4296615_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 547.0
PYH1_k127_4296615_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 362.0
PYH1_k127_4296615_6 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
PYH1_k127_4296615_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 334.0
PYH1_k127_4296615_8 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 337.0
PYH1_k127_4296615_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
PYH1_k127_4297534_0 Proton-conducting membrane transporter - - - 1.163e-305 949.0
PYH1_k127_4297534_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 476.0
PYH1_k127_4297534_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 342.0
PYH1_k127_4297534_3 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 311.0
PYH1_k127_4297534_4 COG3209 Rhs family protein - - - 0.00000000000000000000000000002467 131.0
PYH1_k127_4297534_5 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000001615 98.0
PYH1_k127_4309465_0 Transposase IS116/IS110/IS902 family - - - 9.695e-250 783.0
PYH1_k127_4309726_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1347.0
PYH1_k127_4309726_1 Malic enzyme K00029 - 1.1.1.40 0.0 1130.0
PYH1_k127_4309726_10 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 598.0
PYH1_k127_4309726_11 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 581.0
PYH1_k127_4309726_12 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 556.0
PYH1_k127_4309726_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 467.0
PYH1_k127_4309726_14 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 459.0
PYH1_k127_4309726_15 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 427.0
PYH1_k127_4309726_16 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 405.0
PYH1_k127_4309726_17 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 353.0
PYH1_k127_4309726_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 309.0
PYH1_k127_4309726_19 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 307.0
PYH1_k127_4309726_2 Belongs to the transketolase family K00615 - 2.2.1.1 3.687e-289 904.0
PYH1_k127_4309726_20 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 298.0
PYH1_k127_4309726_21 FHA Domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 293.0
PYH1_k127_4309726_22 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
PYH1_k127_4309726_23 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004091 254.0
PYH1_k127_4309726_24 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000002434 228.0
PYH1_k127_4309726_25 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
PYH1_k127_4309726_26 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
PYH1_k127_4309726_27 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000009946 212.0
PYH1_k127_4309726_28 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000005222 207.0
PYH1_k127_4309726_29 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001559 189.0
PYH1_k127_4309726_3 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 5.651e-264 820.0
PYH1_k127_4309726_30 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000001636 185.0
PYH1_k127_4309726_31 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000104 166.0
PYH1_k127_4309726_32 mRNA catabolic process - - - 0.0000000000000000000000000000000000000007348 156.0
PYH1_k127_4309726_33 ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000000000000000001837 151.0
PYH1_k127_4309726_34 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000005058 152.0
PYH1_k127_4309726_35 zinc-ribbon domain - - - 0.0000000000000000000000000000000000001032 156.0
PYH1_k127_4309726_36 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000002651 153.0
PYH1_k127_4309726_37 Lysin motif - - - 0.000000000000000000000000000000001811 140.0
PYH1_k127_4309726_38 KTSC domain - - - 0.000000000000000000000000000001052 121.0
PYH1_k127_4309726_39 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000001171 119.0
PYH1_k127_4309726_4 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.605e-254 789.0
PYH1_k127_4309726_40 Barstar (barnase inhibitor) - - - 0.0000000000000000000003212 100.0
PYH1_k127_4309726_41 Histidine kinase-like ATPase domain - - - 0.000000000000000000006643 98.0
PYH1_k127_4309726_42 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.0000000000000005129 81.0
PYH1_k127_4309726_44 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000001162 60.0
PYH1_k127_4309726_5 RNB K01147 - 3.1.13.1 3.691e-220 700.0
PYH1_k127_4309726_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.153e-215 679.0
PYH1_k127_4309726_7 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 4.778e-202 638.0
PYH1_k127_4309726_8 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
PYH1_k127_4309726_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 593.0
PYH1_k127_4316723_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1014.0
PYH1_k127_4316723_1 DNA helicase K03657 - 3.6.4.12 1.85e-295 921.0
PYH1_k127_4316723_10 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 290.0
PYH1_k127_4316723_11 Addiction module toxin, RelE StbE family K07334 - - 0.000000000000000000000000000000000004897 138.0
PYH1_k127_4316723_12 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000001147 139.0
PYH1_k127_4316723_13 HIUase/Transthyretin family K07127 - 3.5.2.17 0.000000000000000000000000000005114 124.0
PYH1_k127_4316723_14 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.000000000000000000000000000008781 119.0
PYH1_k127_4316723_15 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000009019 107.0
PYH1_k127_4316723_16 Transposase IS200 like K07491 - - 0.000000000000000000001685 98.0
PYH1_k127_4316723_17 Transposase IS200 like K07491 - - 0.0000000000000000001464 89.0
PYH1_k127_4316723_18 Transposase IS200 like K07491 - - 0.0000000000000000001971 88.0
PYH1_k127_4316723_19 - - - - 0.000000000000121 76.0
PYH1_k127_4316723_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 4.332e-223 700.0
PYH1_k127_4316723_20 DNA integration - - - 0.0000001815 53.0
PYH1_k127_4316723_3 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 601.0
PYH1_k127_4316723_4 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 476.0
PYH1_k127_4316723_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 475.0
PYH1_k127_4316723_6 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 398.0
PYH1_k127_4316723_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 383.0
PYH1_k127_4316723_8 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 365.0
PYH1_k127_4316723_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
PYH1_k127_4316963_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.456e-299 934.0
PYH1_k127_4316963_1 AMP-binding enzyme K00666 - - 2.146e-297 923.0
PYH1_k127_4316963_10 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000001739 170.0
PYH1_k127_4316963_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000002156 149.0
PYH1_k127_4316963_12 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000001468 102.0
PYH1_k127_4316963_13 - - - - 0.0000000000000000000519 98.0
PYH1_k127_4316963_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000001212 68.0
PYH1_k127_4316963_15 Domain of unknown function (DUF1330) - - - 0.00000000006321 67.0
PYH1_k127_4316963_16 aspartyl asparaginyl K12979 - - 0.0001516 48.0
PYH1_k127_4316963_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 8.782e-207 657.0
PYH1_k127_4316963_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 591.0
PYH1_k127_4316963_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 538.0
PYH1_k127_4316963_5 Histidine kinase K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 459.0
PYH1_k127_4316963_6 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
PYH1_k127_4316963_7 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 341.0
PYH1_k127_4316963_8 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 325.0
PYH1_k127_4316963_9 Transcriptional regulator K04033 - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
PYH1_k127_4326919_0 Acyl-CoA dehydrogenase, middle domain - - - 1.483e-213 668.0
PYH1_k127_4326919_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 591.0
PYH1_k127_4326919_10 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000004155 54.0
PYH1_k127_4326919_11 Protein of unknown function (DUF3617) - - - 0.0001163 51.0
PYH1_k127_4326919_13 Tripartite tricarboxylate transporter family receptor - - - 0.000215 44.0
PYH1_k127_4326919_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 344.0
PYH1_k127_4326919_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
PYH1_k127_4326919_4 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
PYH1_k127_4326919_5 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000000000000000002485 145.0
PYH1_k127_4326919_6 Plasmid stabilization system K19092 - - 0.00000000000000000000000000000000000004428 145.0
PYH1_k127_4326919_7 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000003833 153.0
PYH1_k127_4326919_8 GYD domain - - - 0.00000000000000000000000000001804 120.0
PYH1_k127_4326919_9 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000002389 105.0
PYH1_k127_434329_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1628.0
PYH1_k127_434329_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 4.863e-239 746.0
PYH1_k127_434329_10 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 321.0
PYH1_k127_434329_11 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 316.0
PYH1_k127_434329_12 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
PYH1_k127_434329_13 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
PYH1_k127_434329_14 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005605 269.0
PYH1_k127_434329_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005404 260.0
PYH1_k127_434329_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH1_k127_434329_17 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000619 205.0
PYH1_k127_434329_18 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000001047 203.0
PYH1_k127_434329_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001057 179.0
PYH1_k127_434329_2 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 596.0
PYH1_k127_434329_20 Plasmid stabilization system K19092 - - 0.000000000000000000000000000000000000000007529 159.0
PYH1_k127_434329_21 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000001566 126.0
PYH1_k127_434329_22 PIN domain - - - 0.0000000000000000000000000000007552 126.0
PYH1_k127_434329_23 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000015 115.0
PYH1_k127_434329_24 - - - - 0.00000000000000000000000003967 113.0
PYH1_k127_434329_25 - - - - 0.00000000000000000000003174 107.0
PYH1_k127_434329_26 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000006149 91.0
PYH1_k127_434329_27 Domain of unknown function (DUF4160) - - - 0.000000000000000008231 84.0
PYH1_k127_434329_28 mRNA binding K07339 - - 0.00000000000000001443 87.0
PYH1_k127_434329_29 Protein of unknown function (DUF2783) - - - 0.0000000000000006719 79.0
PYH1_k127_434329_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
PYH1_k127_434329_30 Protein of unknown function (DUF2442) - - - 0.00000000000001376 77.0
PYH1_k127_434329_31 Domain of unknown function (DUF4160) - - - 0.0000001962 52.0
PYH1_k127_434329_33 - - - - 0.000004329 51.0
PYH1_k127_434329_34 protein import - - - 0.00001675 50.0
PYH1_k127_434329_35 - - - - 0.00002289 54.0
PYH1_k127_434329_4 periplasmic K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 482.0
PYH1_k127_434329_5 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 498.0
PYH1_k127_434329_6 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 387.0
PYH1_k127_434329_7 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 377.0
PYH1_k127_434329_8 Pfam Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
PYH1_k127_434329_9 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 324.0
PYH1_k127_4354666_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 407.0
PYH1_k127_4354666_1 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000001017 194.0
PYH1_k127_4354666_2 orn lys arg decarboxylase K01583 - 4.1.1.19 0.0000000000000000000000000000000004049 134.0
PYH1_k127_4354666_3 - - - - 0.00000001472 55.0
PYH1_k127_4359280_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1118.0
PYH1_k127_4359280_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1056.0
PYH1_k127_4359280_10 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 594.0
PYH1_k127_4359280_11 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 558.0
PYH1_k127_4359280_12 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 527.0
PYH1_k127_4359280_13 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 452.0
PYH1_k127_4359280_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 455.0
PYH1_k127_4359280_15 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
PYH1_k127_4359280_16 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 364.0
PYH1_k127_4359280_17 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 301.0
PYH1_k127_4359280_18 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
PYH1_k127_4359280_19 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 260.0
PYH1_k127_4359280_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.074e-284 886.0
PYH1_k127_4359280_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005245 273.0
PYH1_k127_4359280_21 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009227 244.0
PYH1_k127_4359280_22 transcriptional regulator, Rrf2 family K13643 - - 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
PYH1_k127_4359280_23 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000006136 225.0
PYH1_k127_4359280_24 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000004367 191.0
PYH1_k127_4359280_25 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000006358 189.0
PYH1_k127_4359280_26 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000006041 176.0
PYH1_k127_4359280_27 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000003538 174.0
PYH1_k127_4359280_28 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000001676 175.0
PYH1_k127_4359280_29 NUDIX domain - - - 0.00000000000000000000000000000000000000000001667 175.0
PYH1_k127_4359280_3 Circularly permuted ATP-grasp type 2 - - - 2.602e-244 762.0
PYH1_k127_4359280_30 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000006393 139.0
PYH1_k127_4359280_31 nitrogen regulatory protein P-II - - - 0.000000000000000000000000000004874 135.0
PYH1_k127_4359280_32 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000009198 112.0
PYH1_k127_4359280_33 Diguanylate cyclase - - - 0.0000000000000000000007072 108.0
PYH1_k127_4359280_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.859e-233 733.0
PYH1_k127_4359280_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.612e-227 706.0
PYH1_k127_4359280_6 single-stranded-DNA-specific exonuclease RecJ K07462 - - 9.018e-215 682.0
PYH1_k127_4359280_7 Competence protein K02238 - - 4.206e-195 636.0
PYH1_k127_4359280_8 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 593.0
PYH1_k127_4359280_9 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 599.0
PYH1_k127_4391096_0 helicase superfamily c-terminal domain K03724 - - 0.0 1069.0
PYH1_k127_4391096_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1030.0
PYH1_k127_4391096_10 PhoD-like phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 449.0
PYH1_k127_4391096_11 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 437.0
PYH1_k127_4391096_12 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 419.0
PYH1_k127_4391096_13 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 382.0
PYH1_k127_4391096_14 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
PYH1_k127_4391096_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 301.0
PYH1_k127_4391096_16 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001545 246.0
PYH1_k127_4391096_17 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000009334 188.0
PYH1_k127_4391096_18 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000002686 183.0
PYH1_k127_4391096_19 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000007439 174.0
PYH1_k127_4391096_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.1e-322 992.0
PYH1_k127_4391096_20 aminopeptidase N - - - 0.0000000000000000000000000000000000001931 159.0
PYH1_k127_4391096_21 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000005185 141.0
PYH1_k127_4391096_22 SWIB/MDM2 domain K03169 - 5.99.1.2 0.0000000000000000000000000000000001134 138.0
PYH1_k127_4391096_23 Regulatory protein, FmdB family - - - 0.00000000000000000000000000002969 122.0
PYH1_k127_4391096_24 - - - - 0.0000000000000000000000000002965 116.0
PYH1_k127_4391096_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000001837 118.0
PYH1_k127_4391096_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000009441 101.0
PYH1_k127_4391096_27 Acetyltransferase (GNAT) domain - - - 0.000000000000000004994 91.0
PYH1_k127_4391096_28 PFAM CBS domain containing protein - - - 0.000000000000002941 89.0
PYH1_k127_4391096_29 PFAM Copper binding periplasmic protein CusF - - - 0.000000000001224 72.0
PYH1_k127_4391096_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.247e-236 747.0
PYH1_k127_4391096_30 PEP-CTERM motif - - - 0.0001153 52.0
PYH1_k127_4391096_4 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 2.96e-231 728.0
PYH1_k127_4391096_5 B12 binding domain - - - 1.016e-204 652.0
PYH1_k127_4391096_6 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 550.0
PYH1_k127_4391096_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 498.0
PYH1_k127_4391096_8 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 496.0
PYH1_k127_4391096_9 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 445.0
PYH1_k127_43929_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 510.0
PYH1_k127_43929_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 490.0
PYH1_k127_43929_10 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000001702 180.0
PYH1_k127_43929_11 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000002103 123.0
PYH1_k127_43929_13 - - - - 0.00000000000001199 82.0
PYH1_k127_43929_14 chaperone-mediated protein folding - - - 0.00000000001525 76.0
PYH1_k127_43929_15 Antibiotic biosynthesis monooxygenase - - - 0.00001315 51.0
PYH1_k127_43929_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 337.0
PYH1_k127_43929_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 307.0
PYH1_k127_43929_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001299 266.0
PYH1_k127_43929_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002997 259.0
PYH1_k127_43929_7 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000003904 198.0
PYH1_k127_43929_8 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000008434 182.0
PYH1_k127_43929_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000001345 177.0
PYH1_k127_4421308_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.697e-264 827.0
PYH1_k127_4421308_1 Glycolate oxidase subunit GlcD K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.631e-230 730.0
PYH1_k127_4421308_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
PYH1_k127_4421308_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 291.0
PYH1_k127_4421308_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 299.0
PYH1_k127_4421308_13 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004897 279.0
PYH1_k127_4421308_14 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000000000009061 212.0
PYH1_k127_4421308_15 COG1226 Kef-type K transport systems - - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
PYH1_k127_4421308_16 Signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000006679 201.0
PYH1_k127_4421308_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000002915 182.0
PYH1_k127_4421308_18 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000001452 155.0
PYH1_k127_4421308_19 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000005803 132.0
PYH1_k127_4421308_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.961e-226 718.0
PYH1_k127_4421308_20 Mitomycin resistance protein K07343 - - 0.0000000000000000000005354 104.0
PYH1_k127_4421308_21 - - - - 0.00000000000000000002129 100.0
PYH1_k127_4421308_22 Dodecin K09165 - - 0.0000000000000000001575 92.0
PYH1_k127_4421308_23 regulator - - - 0.0000000007401 68.0
PYH1_k127_4421308_3 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 8.884e-224 702.0
PYH1_k127_4421308_4 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 604.0
PYH1_k127_4421308_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 581.0
PYH1_k127_4421308_6 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 522.0
PYH1_k127_4421308_7 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 510.0
PYH1_k127_4421308_8 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 448.0
PYH1_k127_4421308_9 FAD binding K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 442.0
PYH1_k127_4427465_0 Formyl transferase K19640 - - 1.381e-212 677.0
PYH1_k127_4427465_1 Belongs to the HypD family K04654 - - 1.828e-201 632.0
PYH1_k127_4427465_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 533.0
PYH1_k127_4427465_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 522.0
PYH1_k127_4427465_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 286.0
PYH1_k127_4427465_5 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000529 198.0
PYH1_k127_4427465_6 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000007866 109.0
PYH1_k127_4427465_7 - - - - 0.0000000000000000000001563 104.0
PYH1_k127_4456908_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.338e-199 639.0
PYH1_k127_4456908_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 517.0
PYH1_k127_4456908_10 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
PYH1_k127_4456908_11 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 334.0
PYH1_k127_4456908_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 306.0
PYH1_k127_4456908_13 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000107 268.0
PYH1_k127_4456908_14 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
PYH1_k127_4456908_15 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
PYH1_k127_4456908_16 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000006342 197.0
PYH1_k127_4456908_17 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000000005347 188.0
PYH1_k127_4456908_18 WHG domain - - - 0.000000000000000000000000000000000000000000000001516 181.0
PYH1_k127_4456908_19 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000000004052 167.0
PYH1_k127_4456908_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 494.0
PYH1_k127_4456908_20 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000001447 156.0
PYH1_k127_4456908_21 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000004119 157.0
PYH1_k127_4456908_22 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000002299 118.0
PYH1_k127_4456908_23 diguanylate cyclase - - - 0.000000000000000004429 89.0
PYH1_k127_4456908_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 489.0
PYH1_k127_4456908_4 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 478.0
PYH1_k127_4456908_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
PYH1_k127_4456908_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 476.0
PYH1_k127_4456908_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 469.0
PYH1_k127_4456908_8 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 454.0
PYH1_k127_4456908_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 355.0
PYH1_k127_4468715_0 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 432.0
PYH1_k127_4468715_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
PYH1_k127_4468715_2 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 309.0
PYH1_k127_4468715_3 GYD domain - - - 0.0000000000000000000000000001378 117.0
PYH1_k127_4468715_4 LCCL domain - - - 0.000000000000006419 78.0
PYH1_k127_4468715_5 SnoaL-like domain - - - 0.00000002413 64.0
PYH1_k127_4480794_0 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
PYH1_k127_4480794_1 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
PYH1_k127_4480794_2 nucleoside-diphosphate sugar epimerase - - - 0.00000000000000000000000000000000000000000000000000000000641 201.0
PYH1_k127_4480794_3 Thioredoxin domain - - - 0.0000000000000000006304 89.0
PYH1_k127_4543102_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.031e-264 828.0
PYH1_k127_4543102_1 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
PYH1_k127_4543102_2 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH1_k127_4543102_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000001019 190.0
PYH1_k127_4543102_4 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000001843 152.0
PYH1_k127_4546997_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.848e-306 952.0
PYH1_k127_4546997_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 519.0
PYH1_k127_4546997_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
PYH1_k127_4546997_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 446.0
PYH1_k127_4546997_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 289.0
PYH1_k127_4546997_5 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000005273 191.0
PYH1_k127_4546997_6 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000001339 170.0
PYH1_k127_4546997_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001426 108.0
PYH1_k127_4552112_0 PFAM amidohydrolase K01464 - 3.5.2.2 1.105e-267 830.0
PYH1_k127_4552112_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 552.0
PYH1_k127_4552112_2 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 377.0
PYH1_k127_4552112_3 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
PYH1_k127_4552112_4 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
PYH1_k127_4552112_5 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000001462 184.0
PYH1_k127_4552112_6 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000002224 145.0
PYH1_k127_4601011_0 transport systems, ATPase components K02056 - 3.6.3.17 5.186e-260 809.0
PYH1_k127_4601011_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 516.0
PYH1_k127_4601011_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 455.0
PYH1_k127_4601011_3 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 378.0
PYH1_k127_4601011_4 Xanthine dehydrogenase accessory protein XdhC K07402 - - 0.000000000000000000000000000000001412 131.0
PYH1_k127_472149_0 FAD linked oxidase domain protein - - - 0.0 1904.0
PYH1_k127_472149_1 - - - - 0.000000000000000000000000000000000000005116 157.0
PYH1_k127_473718_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 542.0
PYH1_k127_473718_1 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
PYH1_k127_473718_2 Ferredoxin K05337 - - 0.0000000000000000000000000000000004418 133.0
PYH1_k127_473718_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000023 115.0
PYH1_k127_473718_4 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000784 53.0
PYH1_k127_4768360_0 Proton-conducting membrane transporter K12141 - - 8.765e-250 779.0
PYH1_k127_4768360_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 561.0
PYH1_k127_4768360_2 hydrogenase 4 membrane K12140 - - 0.000000000000000002269 84.0
PYH1_k127_4798198_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 283.0
PYH1_k127_4798198_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000004969 188.0
PYH1_k127_489212_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1038.0
PYH1_k127_489212_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 5.447e-296 929.0
PYH1_k127_489212_2 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 2.865e-212 683.0
PYH1_k127_489212_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 560.0
PYH1_k127_489212_4 PFAM extracellular solute-binding protein family 1 K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002186 281.0
PYH1_k127_489212_5 Belongs to the ABC transporter superfamily K10111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002731 275.0
PYH1_k127_489212_6 - - - - 0.0000000000000000000000000000000000000000001626 172.0
PYH1_k127_495256_0 Molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 446.0
PYH1_k127_495256_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001451 282.0
PYH1_k127_495256_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000002119 184.0
PYH1_k127_5046458_0 - - - - 0.0000000000000000000000000000000000000000000000000001455 200.0
PYH1_k127_5046458_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000002476 146.0
PYH1_k127_5046458_2 cytochrome - - - 0.000000000000000000000000000142 123.0
PYH1_k127_5046458_3 FeoA K04758 - - 0.0000000002122 66.0
PYH1_k127_5046458_4 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000001124 63.0
PYH1_k127_5057920_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 369.0
PYH1_k127_5057920_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
PYH1_k127_5057920_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000001006 218.0
PYH1_k127_5057920_3 FAD-dependent pyridine - - - 0.000000000000000000000000227 106.0
PYH1_k127_5057920_4 PFAM thiamineS protein - - - 0.000000000000000000000002801 104.0
PYH1_k127_5057920_5 - - - - 0.000000000003674 70.0
PYH1_k127_5057920_6 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000006944 63.0
PYH1_k127_5070918_0 Belongs to the malic enzymes family K00029 - 1.1.1.40 6.558e-320 996.0
PYH1_k127_5070918_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 5.744e-248 774.0
PYH1_k127_5070918_10 aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 409.0
PYH1_k127_5070918_11 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 422.0
PYH1_k127_5070918_12 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 412.0
PYH1_k127_5070918_13 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 367.0
PYH1_k127_5070918_14 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
PYH1_k127_5070918_15 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
PYH1_k127_5070918_16 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
PYH1_k127_5070918_17 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000578 250.0
PYH1_k127_5070918_18 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
PYH1_k127_5070918_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003014 232.0
PYH1_k127_5070918_2 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 2.524e-246 768.0
PYH1_k127_5070918_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
PYH1_k127_5070918_21 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000007083 187.0
PYH1_k127_5070918_22 Formate dehydrogenase gamma subunit K00127 - - 0.000000000000000000000000000000000000000000000004934 182.0
PYH1_k127_5070918_23 OmpA family - - - 0.000000000000000000000000000000000000002431 157.0
PYH1_k127_5070918_24 MaoC like domain - - - 0.000000000000000000000000000000000000004269 151.0
PYH1_k127_5070918_25 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000001313 137.0
PYH1_k127_5070918_26 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000003659 138.0
PYH1_k127_5070918_27 PFAM FecR protein - - - 0.000000000000000000000001483 108.0
PYH1_k127_5070918_28 - - - - 0.000000000000000000001242 98.0
PYH1_k127_5070918_29 - - - - 0.000000000000000007315 93.0
PYH1_k127_5070918_3 Highly conserved protein containing a thioredoxin domain K06888 - - 1.744e-243 770.0
PYH1_k127_5070918_30 STAS domain K06378 - - 0.000000000000002268 81.0
PYH1_k127_5070918_31 Putative transposase - - - 0.000000000002084 67.0
PYH1_k127_5070918_32 Histidine kinase-like ATPase domain - - - 0.00000000001417 72.0
PYH1_k127_5070918_33 - - - - 0.00003086 53.0
PYH1_k127_5070918_4 Phosphoesterase family - - - 2.067e-197 627.0
PYH1_k127_5070918_5 Pyridoxamine 5'-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 571.0
PYH1_k127_5070918_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 510.0
PYH1_k127_5070918_7 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
PYH1_k127_5070918_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 481.0
PYH1_k127_5070918_9 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 440.0
PYH1_k127_5093571_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 8.926e-242 768.0
PYH1_k127_5093571_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.788e-228 727.0
PYH1_k127_5093571_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 468.0
PYH1_k127_5093571_11 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 462.0
PYH1_k127_5093571_12 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 468.0
PYH1_k127_5093571_13 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 458.0
PYH1_k127_5093571_14 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 444.0
PYH1_k127_5093571_15 Mg2 and Co2 transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
PYH1_k127_5093571_16 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
PYH1_k127_5093571_17 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
PYH1_k127_5093571_18 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 352.0
PYH1_k127_5093571_19 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
PYH1_k127_5093571_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.556e-218 688.0
PYH1_k127_5093571_20 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
PYH1_k127_5093571_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381 278.0
PYH1_k127_5093571_22 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 262.0
PYH1_k127_5093571_23 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
PYH1_k127_5093571_24 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001009 239.0
PYH1_k127_5093571_25 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
PYH1_k127_5093571_26 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000001891 229.0
PYH1_k127_5093571_27 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
PYH1_k127_5093571_28 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000001474 212.0
PYH1_k127_5093571_29 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000003735 214.0
PYH1_k127_5093571_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.727e-200 629.0
PYH1_k127_5093571_30 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000001008 201.0
PYH1_k127_5093571_31 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000003881 196.0
PYH1_k127_5093571_32 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000001365 197.0
PYH1_k127_5093571_33 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000177 179.0
PYH1_k127_5093571_34 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000002313 160.0
PYH1_k127_5093571_35 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000388 157.0
PYH1_k127_5093571_36 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000004722 136.0
PYH1_k127_5093571_37 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000002561 135.0
PYH1_k127_5093571_38 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000001915 119.0
PYH1_k127_5093571_39 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000007736 98.0
PYH1_k127_5093571_4 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 617.0
PYH1_k127_5093571_40 - - - - 0.000000000000000002451 89.0
PYH1_k127_5093571_41 - - - - 0.00000000000001405 77.0
PYH1_k127_5093571_42 Tetratricopeptide repeat - - - 0.00000000001654 68.0
PYH1_k127_5093571_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 581.0
PYH1_k127_5093571_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 539.0
PYH1_k127_5093571_7 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 536.0
PYH1_k127_5093571_8 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 543.0
PYH1_k127_5093571_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 509.0
PYH1_k127_5097394_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1558.0
PYH1_k127_5097394_1 L-serine dehydratase K01752 - 4.3.1.17 1.855e-228 719.0
PYH1_k127_5097394_10 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000545 213.0
PYH1_k127_5097394_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000002432 184.0
PYH1_k127_5097394_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000001129 148.0
PYH1_k127_5097394_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 589.0
PYH1_k127_5097394_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 562.0
PYH1_k127_5097394_4 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 532.0
PYH1_k127_5097394_5 D-aminoacylase domain protein K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 518.0
PYH1_k127_5097394_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 458.0
PYH1_k127_5097394_7 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 428.0
PYH1_k127_5097394_8 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 329.0
PYH1_k127_5097394_9 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000002431 215.0
PYH1_k127_5104177_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.346e-213 668.0
PYH1_k127_5104177_1 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.164e-204 651.0
PYH1_k127_5104177_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 486.0
PYH1_k127_5104177_3 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 380.0
PYH1_k127_5104177_4 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008105 276.0
PYH1_k127_5104177_5 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
PYH1_k127_5104177_6 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000003116 186.0
PYH1_k127_5105241_0 Isocitrate lyase K01637 - 4.1.3.1 1.52e-250 777.0
PYH1_k127_5105241_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 527.0
PYH1_k127_5105241_2 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
PYH1_k127_5105241_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 416.0
PYH1_k127_5105241_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 385.0
PYH1_k127_5105241_5 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 314.0
PYH1_k127_5105241_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
PYH1_k127_5105241_7 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
PYH1_k127_5150225_0 Putative metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006501 261.0
PYH1_k127_5150225_1 - - - - 0.0000000000000000000000000000000000000001729 158.0
PYH1_k127_5150225_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000005815 151.0
PYH1_k127_5150225_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000003275 91.0
PYH1_k127_5150225_4 - - - - 0.000000000003408 72.0
PYH1_k127_5159812_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 3e-323 995.0
PYH1_k127_5159812_1 peptidase dimerisation domain protein - - - 2.892e-207 651.0
PYH1_k127_5159812_2 deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 588.0
PYH1_k127_5159812_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 533.0
PYH1_k127_5159812_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007682 290.0
PYH1_k127_5159812_5 Nucleoside-binding outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005108 221.0
PYH1_k127_5159812_6 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000004078 186.0
PYH1_k127_5159812_7 FCD - - - 0.0000000000000000000000000000000000000000000000006677 184.0
PYH1_k127_5159812_8 Domain of unknown function (DUF4124) - - - 0.000002082 56.0
PYH1_k127_5196272_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 425.0
PYH1_k127_5196272_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
PYH1_k127_5196272_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 337.0
PYH1_k127_5196272_3 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 313.0
PYH1_k127_5196272_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 294.0
PYH1_k127_5196272_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000502 256.0
PYH1_k127_5196272_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000001516 175.0
PYH1_k127_5196272_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000036 118.0
PYH1_k127_5196272_8 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000001275 94.0
PYH1_k127_5197712_0 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 313.0
PYH1_k127_5197712_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000006007 81.0
PYH1_k127_5216634_0 Ammonium transporter K03320 - - 3.404e-230 726.0
PYH1_k127_5216634_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 7.947e-199 629.0
PYH1_k127_5216634_10 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 471.0
PYH1_k127_5216634_11 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
PYH1_k127_5216634_12 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 375.0
PYH1_k127_5216634_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 359.0
PYH1_k127_5216634_14 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 348.0
PYH1_k127_5216634_15 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
PYH1_k127_5216634_16 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
PYH1_k127_5216634_17 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 266.0
PYH1_k127_5216634_18 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000249 261.0
PYH1_k127_5216634_19 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 258.0
PYH1_k127_5216634_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.868e-194 613.0
PYH1_k127_5216634_20 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008867 255.0
PYH1_k127_5216634_21 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005008 243.0
PYH1_k127_5216634_22 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003228 237.0
PYH1_k127_5216634_23 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001391 235.0
PYH1_k127_5216634_24 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
PYH1_k127_5216634_25 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
PYH1_k127_5216634_26 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000009062 193.0
PYH1_k127_5216634_27 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000000007525 152.0
PYH1_k127_5216634_28 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000001591 122.0
PYH1_k127_5216634_29 - - - - 0.0000000000000000000000000002662 123.0
PYH1_k127_5216634_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
PYH1_k127_5216634_30 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000001378 114.0
PYH1_k127_5216634_31 Membrane fusogenic activity K09806 - - 0.0000000000000000001933 90.0
PYH1_k127_5216634_32 cytochrome complex assembly - - - 0.000000000008605 76.0
PYH1_k127_5216634_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 586.0
PYH1_k127_5216634_5 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 574.0
PYH1_k127_5216634_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 548.0
PYH1_k127_5216634_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 523.0
PYH1_k127_5216634_8 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 493.0
PYH1_k127_5216634_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 496.0
PYH1_k127_5238208_0 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 0.0 1178.0
PYH1_k127_5238208_1 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000008707 229.0
PYH1_k127_5238208_2 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000001443 161.0
PYH1_k127_5242944_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 394.0
PYH1_k127_5242944_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000002369 145.0
PYH1_k127_5242944_2 PFAM UspA domain protein K07090 - - 0.00000000000000000000000000000005384 138.0
PYH1_k127_5242944_3 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000702 109.0
PYH1_k127_5242944_4 - - - - 0.000000000000000000005034 104.0
PYH1_k127_5251096_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 607.0
PYH1_k127_5251096_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 560.0
PYH1_k127_5251096_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 545.0
PYH1_k127_5251096_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 326.0
PYH1_k127_5251096_4 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000225 240.0
PYH1_k127_5269439_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 6.095e-220 692.0
PYH1_k127_5269439_1 Belongs to the thiolase family - - - 1.398e-211 663.0
PYH1_k127_5269439_2 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 297.0
PYH1_k127_5269439_3 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000006636 108.0
PYH1_k127_5286154_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 381.0
PYH1_k127_5286154_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
PYH1_k127_5286154_2 amino acid ABC transporter K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002607 281.0
PYH1_k127_5286154_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008767 265.0
PYH1_k127_5286154_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005835 252.0
PYH1_k127_5286154_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000003874 185.0
PYH1_k127_5286154_6 Aspartyl protease K06985 - - 0.00000000000000003952 93.0
PYH1_k127_5286154_7 Transposase - - - 0.00000000004264 67.0
PYH1_k127_5296645_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 364.0
PYH1_k127_5296645_1 SnoaL-like domain - - - 0.00000000000000000000000982 104.0
PYH1_k127_5296645_2 PFAM regulatory protein LysR K21645 - - 0.0000000000009899 68.0
PYH1_k127_5306698_0 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.491e-225 699.0
PYH1_k127_5306698_1 MmgE PrpD family protein - - - 1.505e-207 654.0
PYH1_k127_5306698_10 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 359.0
PYH1_k127_5306698_11 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 336.0
PYH1_k127_5306698_12 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005946 253.0
PYH1_k127_5306698_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000001152 241.0
PYH1_k127_5306698_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000003511 148.0
PYH1_k127_5306698_15 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000001045 130.0
PYH1_k127_5306698_16 Dodecin K09165 - - 0.00000000000000000000000000006342 118.0
PYH1_k127_5306698_17 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.0000000000001806 74.0
PYH1_k127_5306698_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.25e-206 650.0
PYH1_k127_5306698_3 CoA-transferase family III K18289 - 2.8.3.22 1.681e-195 626.0
PYH1_k127_5306698_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 582.0
PYH1_k127_5306698_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 583.0
PYH1_k127_5306698_6 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 517.0
PYH1_k127_5306698_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 458.0
PYH1_k127_5306698_8 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 433.0
PYH1_k127_5306698_9 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
PYH1_k127_5347421_0 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 287.0
PYH1_k127_5347421_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001312 276.0
PYH1_k127_5347421_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000778 261.0
PYH1_k127_5347421_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000689 180.0
PYH1_k127_5347421_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000001116 172.0
PYH1_k127_5347421_5 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000001292 143.0
PYH1_k127_5347421_6 Transcriptional regulator - - - 0.0000000000000000000000000000009303 125.0
PYH1_k127_5347421_7 - - - - 0.000000000000000003948 85.0
PYH1_k127_540010_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1134.0
PYH1_k127_540010_1 Acyl-CoA dehydrogenase N terminal - - - 2.686e-271 850.0
PYH1_k127_540010_10 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
PYH1_k127_540010_11 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 337.0
PYH1_k127_540010_12 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 364.0
PYH1_k127_540010_13 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 308.0
PYH1_k127_540010_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 279.0
PYH1_k127_540010_15 PFAM Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000819 271.0
PYH1_k127_540010_16 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
PYH1_k127_540010_17 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
PYH1_k127_540010_18 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
PYH1_k127_540010_19 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000003223 211.0
PYH1_k127_540010_2 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.405e-270 846.0
PYH1_k127_540010_20 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000687 207.0
PYH1_k127_540010_21 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000002787 202.0
PYH1_k127_540010_22 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000001067 174.0
PYH1_k127_540010_23 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000001456 168.0
PYH1_k127_540010_24 TraB family K09973 - - 0.00000000000000000000000000000000000000000003565 172.0
PYH1_k127_540010_25 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000003121 158.0
PYH1_k127_540010_26 hydrogenase maturation protease - - - 0.00000000000000000000000000000000001974 140.0
PYH1_k127_540010_28 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000004475 110.0
PYH1_k127_540010_29 assembly chaperone K07346 - - 0.000000000000000000000001191 114.0
PYH1_k127_540010_3 Acyl-CoA synthetase (NDP forming) K09181 - - 1.399e-259 829.0
PYH1_k127_540010_30 dksA traR - - - 0.0000000000000000001135 94.0
PYH1_k127_540010_31 Spore Coat Protein U domain - - - 0.0000000000000000001931 94.0
PYH1_k127_540010_32 Secreted protein - - - 0.000000000000000006671 90.0
PYH1_k127_540010_33 protein conserved in bacteria - - - 0.000000000000009297 77.0
PYH1_k127_540010_34 Spore Coat Protein U domain - - - 0.00000000000001117 81.0
PYH1_k127_540010_4 CHAT domain - - - 3.357e-256 820.0
PYH1_k127_540010_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 1.08e-248 777.0
PYH1_k127_540010_6 Belongs to the thiolase family K00632 - 2.3.1.16 7.108e-202 634.0
PYH1_k127_540010_7 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 511.0
PYH1_k127_540010_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 444.0
PYH1_k127_540010_9 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 408.0
PYH1_k127_5404556_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 421.0
PYH1_k127_5404556_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 342.0
PYH1_k127_5404556_2 Protein of unknown function (DUF3429) - - - 0.000000000000000000001732 100.0
PYH1_k127_5404556_3 Zinc-binding dehydrogenase - - - 0.00000000000002105 75.0
PYH1_k127_5405449_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 2.646e-206 651.0
PYH1_k127_5405449_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 516.0
PYH1_k127_5405449_2 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 512.0
PYH1_k127_5405449_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000812 259.0
PYH1_k127_5405449_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002322 254.0
PYH1_k127_5405449_5 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000003772 209.0
PYH1_k127_5405449_6 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000001117 203.0
PYH1_k127_5405449_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000009164 147.0
PYH1_k127_5405449_8 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000006307 92.0
PYH1_k127_5432591_0 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000595 235.0
PYH1_k127_5432591_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000008199 191.0
PYH1_k127_5432591_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000006802 138.0
PYH1_k127_5432591_3 - - - - 0.0000000000000001495 81.0
PYH1_k127_5513635_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1098.0
PYH1_k127_5513635_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 1.346e-293 910.0
PYH1_k127_5513635_10 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
PYH1_k127_5513635_11 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 460.0
PYH1_k127_5513635_12 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 448.0
PYH1_k127_5513635_13 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 404.0
PYH1_k127_5513635_14 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 404.0
PYH1_k127_5513635_15 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 362.0
PYH1_k127_5513635_16 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 364.0
PYH1_k127_5513635_17 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 326.0
PYH1_k127_5513635_18 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 305.0
PYH1_k127_5513635_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009238 235.0
PYH1_k127_5513635_2 Belongs to the peptidase S16 family - - - 2.036e-280 882.0
PYH1_k127_5513635_20 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
PYH1_k127_5513635_21 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000007975 220.0
PYH1_k127_5513635_22 carbon monoxide dehydrogenase K09386 - - 0.000000000000000000000000000000000000000000001454 172.0
PYH1_k127_5513635_23 AMP binding - - - 0.0001838 52.0
PYH1_k127_5513635_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.439e-201 631.0
PYH1_k127_5513635_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 559.0
PYH1_k127_5513635_5 TAP-like protein K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 547.0
PYH1_k127_5513635_6 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 505.0
PYH1_k127_5513635_7 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 488.0
PYH1_k127_5513635_8 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 493.0
PYH1_k127_5513635_9 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 490.0
PYH1_k127_5521695_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 1.759e-279 882.0
PYH1_k127_5521695_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 383.0
PYH1_k127_5521695_2 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 327.0
PYH1_k127_5521695_3 d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000951 280.0
PYH1_k127_5521695_4 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
PYH1_k127_5521695_5 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
PYH1_k127_5521695_6 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000885 190.0
PYH1_k127_5521695_7 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000001436 92.0
PYH1_k127_5556609_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 563.0
PYH1_k127_5556609_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 507.0
PYH1_k127_5556609_2 - - - - 0.00000000000000000000000000000000000000000000008941 175.0
PYH1_k127_5556609_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001656 109.0
PYH1_k127_5556609_4 Sel1-like repeats. K07126 - - 0.0000002642 58.0
PYH1_k127_5562253_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 3.427e-287 897.0
PYH1_k127_5562253_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.195e-259 817.0
PYH1_k127_5562253_10 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000265 93.0
PYH1_k127_5562253_11 HEPN domain - - - 0.0000000000000001782 86.0
PYH1_k127_5562253_12 LemA family - - - 0.00000000006319 66.0
PYH1_k127_5562253_13 thiolester hydrolase activity K17362 - - 0.0000000001172 68.0
PYH1_k127_5562253_2 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 437.0
PYH1_k127_5562253_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000007471 251.0
PYH1_k127_5562253_4 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007962 242.0
PYH1_k127_5562253_5 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000003672 233.0
PYH1_k127_5562253_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000002032 186.0
PYH1_k127_5562253_7 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000000000001095 145.0
PYH1_k127_5562253_8 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000001508 113.0
PYH1_k127_5562253_9 PFAM Small Multidrug Resistance protein K03297 - - 0.00000000000000000000003446 109.0
PYH1_k127_5598742_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000001815 159.0
PYH1_k127_5598742_1 Diguanylate cyclase K13069 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209 2.7.7.65 0.0000000000000000000000000000000000001269 148.0
PYH1_k127_5598742_2 protein conserved in bacteria - - - 0.000000000000000000000000000000177 128.0
PYH1_k127_5598742_3 Diguanylate cyclase K13069 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209 2.7.7.65 0.0000000000000000000000000005205 117.0
PYH1_k127_5598742_4 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000001594 108.0
PYH1_k127_5598742_5 - - - - 0.00000000000000000000004315 101.0
PYH1_k127_5598742_6 carboxylic ester hydrolase activity K03929 - - 0.0000000003465 68.0
PYH1_k127_5598742_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000001046 54.0
PYH1_k127_570396_0 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 331.0
PYH1_k127_570396_1 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 304.0
PYH1_k127_574134_0 Protein of unknown function - - - 5.081e-276 897.0
PYH1_k127_574134_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 4.364e-266 851.0
PYH1_k127_574134_10 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
PYH1_k127_574134_11 mechanosensitive ion channel K03442,K16052 - - 0.0000000000000000000000000000000000000000000000000000008208 200.0
PYH1_k127_574134_12 Domain of unknown function (DUF3597) - - - 0.00000000000000000000000000000000000000000000000000007433 194.0
PYH1_k127_574134_13 TIR domain - - - 0.000000000000000000000000001777 129.0
PYH1_k127_574134_14 Pilus assembly protein, PilO - - - 0.000000000000000001034 99.0
PYH1_k127_574134_15 - - - - 0.0000000000005548 78.0
PYH1_k127_574134_16 - - - - 0.000000000003712 77.0
PYH1_k127_574134_17 Major facilitator superfamily - - - 0.0005817 44.0
PYH1_k127_574134_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.031e-215 685.0
PYH1_k127_574134_3 peptidase U62, modulator of DNA gyrase K03568 - - 4.889e-213 674.0
PYH1_k127_574134_4 Secretin and TonB N terminus short domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 556.0
PYH1_k127_574134_5 PFAM type II secretion system K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 395.0
PYH1_k127_574134_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
PYH1_k127_574134_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 370.0
PYH1_k127_574134_8 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 267.0
PYH1_k127_574134_9 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
PYH1_k127_5779993_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.877e-290 899.0
PYH1_k127_5779993_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 544.0
PYH1_k127_5779993_2 UTRA domain K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 344.0
PYH1_k127_5779993_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 321.0
PYH1_k127_5779993_4 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000001999 188.0
PYH1_k127_5779993_5 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000000000000003313 175.0
PYH1_k127_5779993_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002049 83.0
PYH1_k127_580653_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002493 259.0
PYH1_k127_580653_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000009011 173.0
PYH1_k127_580653_2 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000004808 109.0
PYH1_k127_580653_3 receptor K16087 - - 0.0000000000000000000009599 100.0
PYH1_k127_580653_4 redox protein, regulator of disulfide bond formation - - - 0.0000000000003389 81.0
PYH1_k127_5829382_0 B12 binding domain - - - 1.249e-208 666.0
PYH1_k127_5829382_1 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 2.217e-200 640.0
PYH1_k127_5829382_2 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 368.0
PYH1_k127_5829382_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000004589 231.0
PYH1_k127_5829382_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
PYH1_k127_5829382_5 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000000000003666 137.0
PYH1_k127_5829382_6 NHL repeat - - - 0.0000000000000000000000000000007144 121.0
PYH1_k127_5829382_7 amine dehydrogenase activity K13730 - - 0.000000000000000000000000000213 128.0
PYH1_k127_5829382_8 - - - - 0.000000000000000000005699 104.0
PYH1_k127_5829382_9 Outer membrane protein beta-barrel domain - - - 0.0000000000000001415 88.0
PYH1_k127_5874348_0 FtsX-like permease family K02004 - - 6.87e-280 883.0
PYH1_k127_5874348_1 Tripartite tricarboxylate transporter TctA family - - - 9.078e-253 788.0
PYH1_k127_5874348_10 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009597 254.0
PYH1_k127_5874348_11 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000328 197.0
PYH1_k127_5874348_12 - - - - 0.00000000000000000000000000000000000000000002655 167.0
PYH1_k127_5874348_13 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000001285 161.0
PYH1_k127_5874348_14 protein conserved in bacteria K09966 - - 0.00000000000000000000000363 106.0
PYH1_k127_5874348_15 PIN domain - - - 0.0000000000000000000008544 102.0
PYH1_k127_5874348_16 3' exoribonuclease, RNase T-like - - - 0.0000333 57.0
PYH1_k127_5874348_2 Aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 505.0
PYH1_k127_5874348_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 484.0
PYH1_k127_5874348_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 470.0
PYH1_k127_5874348_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 463.0
PYH1_k127_5874348_6 DNA recombination protein, rmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
PYH1_k127_5874348_7 major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 335.0
PYH1_k127_5874348_8 Elements of external origin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 282.0
PYH1_k127_5874348_9 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
PYH1_k127_5878101_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1308.0
PYH1_k127_5878101_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 317.0
PYH1_k127_5878101_2 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
PYH1_k127_5878101_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000003411 158.0
PYH1_k127_5878101_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000001254 74.0
PYH1_k127_5886839_0 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
PYH1_k127_5886839_1 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 298.0
PYH1_k127_5886839_2 Phage integrase family - - - 0.00000000000000000001024 94.0
PYH1_k127_5886839_3 Belongs to the 'phage' integrase family - - - 0.000000001481 60.0
PYH1_k127_5894043_0 CoA binding domain - - - 3.636e-296 923.0
PYH1_k127_5894043_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 351.0
PYH1_k127_5894043_2 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000102 215.0
PYH1_k127_5894043_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000002929 188.0
PYH1_k127_5896176_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1294.0
PYH1_k127_5896176_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.476e-267 837.0
PYH1_k127_5896176_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 1.042e-207 661.0
PYH1_k127_5896176_3 PFAM multicopper oxidase type K04753,K08100,K14588 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 312.0
PYH1_k127_5896176_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
PYH1_k127_5896176_5 Proteasome subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
PYH1_k127_5896176_6 - - - - 0.000000000000000000000000000000000000000007163 163.0
PYH1_k127_5896176_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000004461 105.0
PYH1_k127_5899339_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.581e-266 834.0
PYH1_k127_5899339_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.011e-214 676.0
PYH1_k127_5899339_10 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
PYH1_k127_5899339_11 Lysine exporter protein (Lyse ygga) K11250 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 291.0
PYH1_k127_5899339_12 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
PYH1_k127_5899339_13 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000259 285.0
PYH1_k127_5899339_14 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000008012 269.0
PYH1_k127_5899339_15 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
PYH1_k127_5899339_16 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
PYH1_k127_5899339_17 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003904 252.0
PYH1_k127_5899339_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000001468 254.0
PYH1_k127_5899339_19 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
PYH1_k127_5899339_2 Cell shape determining protein, MreB Mrl family K03569 - - 6.885e-199 624.0
PYH1_k127_5899339_20 HIT domain - - - 0.00000000000000000000000000000000000000000000003537 174.0
PYH1_k127_5899339_21 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000002361 179.0
PYH1_k127_5899339_22 Ferredoxin - - - 0.0000000000000000000000000000000000000000000009851 167.0
PYH1_k127_5899339_23 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000004607 164.0
PYH1_k127_5899339_24 SMART Transport-associated and nodulation region - - - 0.00000000000000000000000000000000000000000087 164.0
PYH1_k127_5899339_25 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000001503 164.0
PYH1_k127_5899339_26 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000817 156.0
PYH1_k127_5899339_27 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000005803 151.0
PYH1_k127_5899339_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000012 121.0
PYH1_k127_5899339_29 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000001474 119.0
PYH1_k127_5899339_3 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 602.0
PYH1_k127_5899339_30 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001659 123.0
PYH1_k127_5899339_31 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000006066 116.0
PYH1_k127_5899339_32 PFAM Sporulation domain protein - - - 0.00000000001709 74.0
PYH1_k127_5899339_33 - - - - 0.0000000004963 67.0
PYH1_k127_5899339_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 541.0
PYH1_k127_5899339_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 514.0
PYH1_k127_5899339_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
PYH1_k127_5899339_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 382.0
PYH1_k127_5899339_8 PFAM Serine threonine protein kinase-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 377.0
PYH1_k127_5899339_9 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
PYH1_k127_5916744_0 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000001653 239.0
PYH1_k127_5916744_1 Ankyrin repeats (3 copies) K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000004583 194.0
PYH1_k127_5916744_2 PQQ enzyme repeat - - - 0.000000000000000000000000000000009853 132.0
PYH1_k127_5919122_0 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 409.0
PYH1_k127_5919122_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000155 278.0
PYH1_k127_5936691_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1175.0
PYH1_k127_5936691_1 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 527.0
PYH1_k127_5936691_2 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 426.0
PYH1_k127_5936691_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002554 229.0
PYH1_k127_5936691_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000006925 158.0
PYH1_k127_59469_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.359e-240 753.0
PYH1_k127_59469_1 Penicillin amidase K01434 - 3.5.1.11 2.16e-235 754.0
PYH1_k127_59469_10 Dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 406.0
PYH1_k127_59469_11 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 398.0
PYH1_k127_59469_12 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 385.0
PYH1_k127_59469_13 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 365.0
PYH1_k127_59469_14 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 367.0
PYH1_k127_59469_15 Type ii and iii secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 296.0
PYH1_k127_59469_16 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
PYH1_k127_59469_17 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
PYH1_k127_59469_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000003445 213.0
PYH1_k127_59469_19 nucleoside-diphosphate sugar epimerase - - - 0.00000000000000000000000000000000000000000000005348 177.0
PYH1_k127_59469_2 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 1.626e-222 702.0
PYH1_k127_59469_21 - - - - 0.00000000000001169 80.0
PYH1_k127_59469_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 583.0
PYH1_k127_59469_4 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 523.0
PYH1_k127_59469_5 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 522.0
PYH1_k127_59469_6 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 495.0
PYH1_k127_59469_7 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
PYH1_k127_59469_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 452.0
PYH1_k127_59469_9 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 426.0
PYH1_k127_5950726_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 3.299e-215 682.0
PYH1_k127_5950726_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 1.084e-202 645.0
PYH1_k127_5950726_2 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 569.0
PYH1_k127_5950726_3 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 400.0
PYH1_k127_5950726_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 300.0
PYH1_k127_5950726_5 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.000000004341 57.0
PYH1_k127_595954_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 6.62e-238 747.0
PYH1_k127_595954_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000001055 219.0
PYH1_k127_595954_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004713 216.0
PYH1_k127_595954_3 phosphinothricin N-acetyltransferase activity K09181 - - 0.0000000000000000000000000000000000000000000000000001419 188.0
PYH1_k127_595954_4 Gram-negative porin - - - 0.000000000000000001589 94.0
PYH1_k127_5977964_0 Protein of unknown function (DUF1329) - - - 2.082e-221 694.0
PYH1_k127_5977964_1 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 338.0
PYH1_k127_5977964_2 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
PYH1_k127_5977964_3 Methylamine dehydrogenase accessory protein MauD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004028 250.0
PYH1_k127_5977964_4 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000001762 145.0
PYH1_k127_5977964_5 Cytochrome c - - - 0.0000000000000000000000000001753 121.0
PYH1_k127_5977964_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001675 93.0
PYH1_k127_5977997_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1481.0
PYH1_k127_5977997_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1281.0
PYH1_k127_5977997_10 Outer membrane protein beta-barrel family K02014 - - 1.017e-213 689.0
PYH1_k127_5977997_11 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 9.457e-210 655.0
PYH1_k127_5977997_12 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.627e-208 654.0
PYH1_k127_5977997_13 Protein of unknown function (DUF2867) - - - 4.139e-205 650.0
PYH1_k127_5977997_14 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.906e-200 633.0
PYH1_k127_5977997_15 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.259e-199 629.0
PYH1_k127_5977997_16 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 606.0
PYH1_k127_5977997_17 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 604.0
PYH1_k127_5977997_18 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 578.0
PYH1_k127_5977997_19 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 580.0
PYH1_k127_5977997_2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1138.0
PYH1_k127_5977997_20 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 567.0
PYH1_k127_5977997_21 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 561.0
PYH1_k127_5977997_22 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 556.0
PYH1_k127_5977997_23 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 565.0
PYH1_k127_5977997_24 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 551.0
PYH1_k127_5977997_25 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 546.0
PYH1_k127_5977997_26 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 543.0
PYH1_k127_5977997_27 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 543.0
PYH1_k127_5977997_28 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 537.0
PYH1_k127_5977997_29 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 525.0
PYH1_k127_5977997_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.458e-279 868.0
PYH1_k127_5977997_30 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 524.0
PYH1_k127_5977997_31 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 503.0
PYH1_k127_5977997_32 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 501.0
PYH1_k127_5977997_33 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 487.0
PYH1_k127_5977997_34 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 482.0
PYH1_k127_5977997_35 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 449.0
PYH1_k127_5977997_36 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 426.0
PYH1_k127_5977997_37 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 436.0
PYH1_k127_5977997_38 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 410.0
PYH1_k127_5977997_39 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 392.0
PYH1_k127_5977997_4 ABC transporter transmembrane region K06147 - - 4.67e-265 828.0
PYH1_k127_5977997_40 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 388.0
PYH1_k127_5977997_41 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
PYH1_k127_5977997_42 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
PYH1_k127_5977997_43 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
PYH1_k127_5977997_44 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 358.0
PYH1_k127_5977997_45 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 355.0
PYH1_k127_5977997_46 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 352.0
PYH1_k127_5977997_47 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 351.0
PYH1_k127_5977997_48 COG3293 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 328.0
PYH1_k127_5977997_49 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 326.0
PYH1_k127_5977997_5 ABC-type multidrug transport system, ATPase and permease K06147 - - 6.828e-261 815.0
PYH1_k127_5977997_50 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 332.0
PYH1_k127_5977997_51 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
PYH1_k127_5977997_52 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 299.0
PYH1_k127_5977997_53 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
PYH1_k127_5977997_54 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001726 282.0
PYH1_k127_5977997_55 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003502 280.0
PYH1_k127_5977997_56 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001616 272.0
PYH1_k127_5977997_57 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 254.0
PYH1_k127_5977997_58 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
PYH1_k127_5977997_59 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
PYH1_k127_5977997_6 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 8.829e-253 792.0
PYH1_k127_5977997_60 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004171 239.0
PYH1_k127_5977997_61 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
PYH1_k127_5977997_63 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000004628 225.0
PYH1_k127_5977997_64 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000000187 199.0
PYH1_k127_5977997_65 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
PYH1_k127_5977997_66 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000008055 195.0
PYH1_k127_5977997_67 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000114 189.0
PYH1_k127_5977997_68 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000002589 182.0
PYH1_k127_5977997_69 - - - - 0.0000000000000000000000000000000000000000007047 166.0
PYH1_k127_5977997_7 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.493e-249 780.0
PYH1_k127_5977997_70 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000082 155.0
PYH1_k127_5977997_71 diguanylate cyclase - - - 0.0000000000000000000000000000000000000001589 162.0
PYH1_k127_5977997_72 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000004352 138.0
PYH1_k127_5977997_73 Histidine kinase - - - 0.000000000000000000000000000000001766 133.0
PYH1_k127_5977997_74 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000376 131.0
PYH1_k127_5977997_75 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000000000000000006956 132.0
PYH1_k127_5977997_76 flagellar protein FliS K02422 - - 0.000000000000000000000000000002619 125.0
PYH1_k127_5977997_77 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000001047 93.0
PYH1_k127_5977997_78 Beta/Gamma crystallin - - - 0.0000000000000000002629 88.0
PYH1_k127_5977997_79 Flagellar protein FliT K02423 - - 0.000000000000000001987 92.0
PYH1_k127_5977997_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.277e-219 687.0
PYH1_k127_5977997_80 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001142 83.0
PYH1_k127_5977997_81 Aldo/keto reductase family - - - 0.0000000000000009428 78.0
PYH1_k127_5977997_82 - - - - 0.00000000000002327 82.0
PYH1_k127_5977997_83 HMMPfam hit to PF00665, Integrase core domain, score 4.5e-41 K07497 - - 0.00000000000007114 78.0
PYH1_k127_5977997_84 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000001216 74.0
PYH1_k127_5977997_85 Membrane - - - 0.00000000001531 74.0
PYH1_k127_5977997_86 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000007652 72.0
PYH1_k127_5977997_87 - K06950 - - 0.000000002453 63.0
PYH1_k127_5977997_88 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000009039 64.0
PYH1_k127_5977997_89 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000009583 61.0
PYH1_k127_5977997_9 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 3.24e-217 689.0
PYH1_k127_5977997_90 Flagellar regulator YcgR - - - 0.00000002731 64.0
PYH1_k127_5977997_91 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000001756 53.0
PYH1_k127_5977997_94 Protein of unknown function (DUF721) - - - 0.0005437 49.0
PYH1_k127_5991650_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 497.0
PYH1_k127_5991650_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 395.0
PYH1_k127_5991650_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
PYH1_k127_5991650_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 319.0
PYH1_k127_5991650_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001095 251.0
PYH1_k127_5991650_5 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000000005277 202.0
PYH1_k127_5991650_6 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
PYH1_k127_5991650_7 SnoaL-like domain - - - 0.0000000000000000000000000000001423 129.0
PYH1_k127_5991650_8 Zinc-finger domain - - - 0.000000000000000000000001159 106.0
PYH1_k127_5991650_9 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000009149 101.0
PYH1_k127_6033654_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1308.0
PYH1_k127_6033654_1 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
PYH1_k127_6033654_2 PQ loop repeat K15383 - - 0.000000000000000000008115 94.0
PYH1_k127_6034710_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 447.0
PYH1_k127_6034710_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 442.0
PYH1_k127_6034710_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 304.0
PYH1_k127_6034710_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000153 169.0
PYH1_k127_6034710_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000008111 100.0
PYH1_k127_6052799_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 8.95e-246 765.0
PYH1_k127_6052799_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000002767 149.0
PYH1_k127_6052799_2 Cytochrome c K17223 - - 0.00000000001252 64.0
PYH1_k127_6054967_0 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
PYH1_k127_6054967_1 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.00000000000000000000000000000000000000000005098 164.0
PYH1_k127_6054967_2 glycine betaine K05847 - - 0.0000000000000000000000000000006309 125.0
PYH1_k127_6064482_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1317.0
PYH1_k127_6064482_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 598.0
PYH1_k127_6064482_10 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 327.0
PYH1_k127_6064482_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
PYH1_k127_6064482_12 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009441 275.0
PYH1_k127_6064482_13 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000044 275.0
PYH1_k127_6064482_14 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
PYH1_k127_6064482_15 Tat pathway signal - - - 0.000000000000000000000000000000000000000000000000000000000000000000003721 240.0
PYH1_k127_6064482_16 Tat pathway signal - - - 0.000000000000000000000000000000000000000000004078 177.0
PYH1_k127_6064482_17 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000001829 164.0
PYH1_k127_6064482_19 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000004691 104.0
PYH1_k127_6064482_2 Pilus retraction K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 582.0
PYH1_k127_6064482_20 Protein of unknown function (DUF1501) - - - 0.000000000001661 74.0
PYH1_k127_6064482_21 Protein of unknown function (DUF1800) - - - 0.00000294 51.0
PYH1_k127_6064482_3 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 581.0
PYH1_k127_6064482_4 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 609.0
PYH1_k127_6064482_5 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 538.0
PYH1_k127_6064482_6 THUMP domain K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 435.0
PYH1_k127_6064482_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 355.0
PYH1_k127_6064482_8 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
PYH1_k127_6064482_9 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
PYH1_k127_608151_0 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 490.0
PYH1_k127_608151_1 abc transporter atp-binding protein K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 358.0
PYH1_k127_608151_2 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 291.0
PYH1_k127_608151_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000001063 93.0
PYH1_k127_6083033_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 528.0
PYH1_k127_6083033_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 464.0
PYH1_k127_6083033_2 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 319.0
PYH1_k127_6083033_3 tetR family - - - 0.000000000000000000000000000000000000000000000000000001744 196.0
PYH1_k127_6169343_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.169e-234 743.0
PYH1_k127_6169343_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 525.0
PYH1_k127_6169343_2 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 298.0
PYH1_k127_6169343_3 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000198 184.0
PYH1_k127_6169343_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000008489 169.0
PYH1_k127_6173511_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1428.0
PYH1_k127_6173511_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1301.0
PYH1_k127_6173511_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 482.0
PYH1_k127_6173511_11 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 445.0
PYH1_k127_6173511_12 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
PYH1_k127_6173511_13 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 408.0
PYH1_k127_6173511_14 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 402.0
PYH1_k127_6173511_15 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 370.0
PYH1_k127_6173511_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 338.0
PYH1_k127_6173511_17 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 318.0
PYH1_k127_6173511_18 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
PYH1_k127_6173511_19 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 304.0
PYH1_k127_6173511_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.295e-227 711.0
PYH1_k127_6173511_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 289.0
PYH1_k127_6173511_21 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
PYH1_k127_6173511_22 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006187 299.0
PYH1_k127_6173511_23 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
PYH1_k127_6173511_24 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001448 263.0
PYH1_k127_6173511_25 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
PYH1_k127_6173511_26 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000005998 237.0
PYH1_k127_6173511_27 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
PYH1_k127_6173511_28 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000354 204.0
PYH1_k127_6173511_29 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000002625 183.0
PYH1_k127_6173511_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.901e-222 694.0
PYH1_k127_6173511_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000003788 149.0
PYH1_k127_6173511_31 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000009614 148.0
PYH1_k127_6173511_32 Protein of unknown function (DUF465) - - - 0.00000000000000002227 83.0
PYH1_k127_6173511_33 - - - - 0.000000000000001346 87.0
PYH1_k127_6173511_35 - - - - 0.0003345 45.0
PYH1_k127_6173511_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.02e-216 681.0
PYH1_k127_6173511_5 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.995e-206 658.0
PYH1_k127_6173511_6 Belongs to the thiolase family K00626 - 2.3.1.9 7.479e-199 627.0
PYH1_k127_6173511_7 HELICc2 K03722 - 3.6.4.12 3.282e-196 636.0
PYH1_k127_6173511_8 Belongs to the thiolase family K00626 - 2.3.1.9 7.301e-195 613.0
PYH1_k127_6173511_9 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 566.0
PYH1_k127_6179291_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.3e-203 651.0
PYH1_k127_6179291_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 509.0
PYH1_k127_6179291_2 COG3245 Cytochrome c5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000253 243.0
PYH1_k127_6179291_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000001438 207.0
PYH1_k127_6179291_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000451 163.0
PYH1_k127_6179291_5 pilus modification protein PilV K02671 - - 0.00000000000000000000004751 108.0
PYH1_k127_6179291_6 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.000000000000000000006285 93.0
PYH1_k127_6179291_7 TonB family K03832 - - 0.000000000000000009938 90.0
PYH1_k127_6179291_8 Type II transport protein GspH K08084 - - 0.00000000000000008903 89.0
PYH1_k127_6179291_9 general secretion pathway protein K08084,K08085 - - 0.0000000000298 75.0
PYH1_k127_6181312_0 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 424.0
PYH1_k127_6181312_1 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000000000000000000000000000000000001977 158.0
PYH1_k127_6181312_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000004887 108.0
PYH1_k127_621336_0 Evidence 2b Function of strongly homologous gene - - - 7.244e-253 788.0
PYH1_k127_621336_1 Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein) - - - 1.065e-195 622.0
PYH1_k127_621336_2 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 441.0
PYH1_k127_621336_3 DNA replication protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009845 252.0
PYH1_k127_621336_4 - - - - 0.0000000000000000000000000008992 117.0
PYH1_k127_6220746_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.289e-266 830.0
PYH1_k127_6220746_1 Cytochrome b(N-terminal)/b6/petB - - - 2.876e-231 732.0
PYH1_k127_6220746_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000009095 187.0
PYH1_k127_6220746_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000002995 180.0
PYH1_k127_6220746_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000001918 174.0
PYH1_k127_6220746_13 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000003467 176.0
PYH1_k127_6220746_14 - - - - 0.0000000000000000000000000000000000000000001496 168.0
PYH1_k127_6220746_15 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000001863 156.0
PYH1_k127_6220746_16 Histidine kinase - - - 0.000000000000000000000000000000000003613 142.0
PYH1_k127_6220746_17 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000007933 119.0
PYH1_k127_6220746_18 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.000000000000000000006986 92.0
PYH1_k127_6220746_19 - - - - 0.000000000006631 68.0
PYH1_k127_6220746_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 516.0
PYH1_k127_6220746_20 Histidine kinase - - - 0.0000000214 55.0
PYH1_k127_6220746_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 407.0
PYH1_k127_6220746_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 385.0
PYH1_k127_6220746_5 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 321.0
PYH1_k127_6220746_6 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
PYH1_k127_6220746_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
PYH1_k127_6220746_8 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
PYH1_k127_6220746_9 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000009388 219.0
PYH1_k127_6223886_0 TIGRFAM rfaE bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
PYH1_k127_6223886_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 365.0
PYH1_k127_6223886_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
PYH1_k127_6223886_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000003706 209.0
PYH1_k127_6223886_4 PIN domain - - - 0.00000000000000000000000000116 116.0
PYH1_k127_6223886_5 SpoVT / AbrB like domain - - - 0.00000000000332 70.0
PYH1_k127_6248687_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1024.0
PYH1_k127_6248687_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 8.319e-318 982.0
PYH1_k127_6248687_10 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 346.0
PYH1_k127_6248687_11 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
PYH1_k127_6248687_12 COG0451 Nucleoside-diphosphate-sugar epimerases K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
PYH1_k127_6248687_13 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
PYH1_k127_6248687_14 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
PYH1_k127_6248687_15 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000003058 192.0
PYH1_k127_6248687_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000001099 185.0
PYH1_k127_6248687_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000178 163.0
PYH1_k127_6248687_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000003927 142.0
PYH1_k127_6248687_19 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001144 111.0
PYH1_k127_6248687_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.006e-282 871.0
PYH1_k127_6248687_20 ATP synthase I chain K02116 - - 0.00000000000000000408 88.0
PYH1_k127_6248687_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 589.0
PYH1_k127_6248687_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 423.0
PYH1_k127_6248687_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
PYH1_k127_6248687_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
PYH1_k127_6248687_7 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 399.0
PYH1_k127_6248687_8 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 387.0
PYH1_k127_6248687_9 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 348.0
PYH1_k127_6390227_0 ABC transporter transmembrane region K06147,K18893 - - 5.172e-266 831.0
PYH1_k127_6390227_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001186 258.0
PYH1_k127_6390227_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000002645 190.0
PYH1_k127_6390227_3 PFAM 5'-nucleotidase, C-terminal domain K07004 - - 0.0000000000000000000000000000000000000000000000003227 181.0
PYH1_k127_6390227_4 nucleic-acid-binding protein, contains PIN domain - - - 0.000000000000000000000000006683 117.0
PYH1_k127_6390227_5 Protein of unknown function (DUF1778) - - - 0.000000000000000000002762 96.0
PYH1_k127_6390227_6 SpoVT / AbrB like domain - - - 0.00000000000001464 76.0
PYH1_k127_6418651_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.127e-219 690.0
PYH1_k127_6418651_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.934e-210 662.0
PYH1_k127_6418651_10 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 416.0
PYH1_k127_6418651_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 412.0
PYH1_k127_6418651_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 401.0
PYH1_k127_6418651_13 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
PYH1_k127_6418651_14 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
PYH1_k127_6418651_15 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 364.0
PYH1_k127_6418651_16 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 337.0
PYH1_k127_6418651_17 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 328.0
PYH1_k127_6418651_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 316.0
PYH1_k127_6418651_19 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
PYH1_k127_6418651_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 580.0
PYH1_k127_6418651_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
PYH1_k127_6418651_21 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
PYH1_k127_6418651_22 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004718 277.0
PYH1_k127_6418651_23 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
PYH1_k127_6418651_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 266.0
PYH1_k127_6418651_25 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000009876 234.0
PYH1_k127_6418651_26 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000002497 230.0
PYH1_k127_6418651_27 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000006253 213.0
PYH1_k127_6418651_28 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000002298 209.0
PYH1_k127_6418651_29 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000003291 192.0
PYH1_k127_6418651_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 563.0
PYH1_k127_6418651_30 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000006532 188.0
PYH1_k127_6418651_31 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000006812 179.0
PYH1_k127_6418651_32 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000001708 181.0
PYH1_k127_6418651_33 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000003376 172.0
PYH1_k127_6418651_34 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000002369 147.0
PYH1_k127_6418651_35 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000000000000008726 144.0
PYH1_k127_6418651_36 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000009591 144.0
PYH1_k127_6418651_37 protein domain associated with - - - 0.0000000000000000000000000000000001305 144.0
PYH1_k127_6418651_38 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000002352 123.0
PYH1_k127_6418651_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000002607 109.0
PYH1_k127_6418651_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 531.0
PYH1_k127_6418651_40 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000004086 93.0
PYH1_k127_6418651_41 NTP binding protein (Contains STAS domain) K04749,K07122 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716 - 0.000000000000004601 78.0
PYH1_k127_6418651_42 FR47-like protein K06976 - - 0.0000000000008401 73.0
PYH1_k127_6418651_43 Cytochrome c K17760 - 1.1.9.1 0.000000000001898 68.0
PYH1_k127_6418651_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 525.0
PYH1_k127_6418651_6 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 451.0
PYH1_k127_6418651_7 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 441.0
PYH1_k127_6418651_8 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 434.0
PYH1_k127_6418651_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 431.0
PYH1_k127_6558752_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1324.0
PYH1_k127_6558752_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 2.317e-277 879.0
PYH1_k127_6558752_10 succinylglutamate desuccinylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 409.0
PYH1_k127_6558752_11 PFAM ABC transporter related K10017,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
PYH1_k127_6558752_12 Ligated ion channel L-glutamate- and glycine-binding site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
PYH1_k127_6558752_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 331.0
PYH1_k127_6558752_14 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 315.0
PYH1_k127_6558752_15 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 317.0
PYH1_k127_6558752_16 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH1_k127_6558752_17 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
PYH1_k127_6558752_18 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
PYH1_k127_6558752_19 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 295.0
PYH1_k127_6558752_2 FtsX-like permease family K02004 - - 2.319e-210 681.0
PYH1_k127_6558752_20 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006932 271.0
PYH1_k127_6558752_21 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004664 269.0
PYH1_k127_6558752_22 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 269.0
PYH1_k127_6558752_23 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003134 249.0
PYH1_k127_6558752_24 PFAM pyridoxamine 5-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
PYH1_k127_6558752_25 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001312 225.0
PYH1_k127_6558752_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001001 226.0
PYH1_k127_6558752_27 Glyoxalase bleomycin resistance - - - 0.0000000000000000000000000000000000000000000000000009705 185.0
PYH1_k127_6558752_28 enzyme binding - - - 0.000000000000000000000000000001065 127.0
PYH1_k127_6558752_29 Protein of unknown function (DUF1059) - - - 0.0000000000000000000000006435 106.0
PYH1_k127_6558752_3 Peptidase C39 family K13409 - - 1.225e-205 664.0
PYH1_k127_6558752_30 - - - - 0.0000001623 53.0
PYH1_k127_6558752_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 600.0
PYH1_k127_6558752_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 544.0
PYH1_k127_6558752_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
PYH1_k127_6558752_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 497.0
PYH1_k127_6558752_8 Lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 458.0
PYH1_k127_6558752_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 418.0
PYH1_k127_6732360_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.738e-258 815.0
PYH1_k127_6732360_1 Multicopper oxidase - - - 6.999e-246 777.0
PYH1_k127_6732360_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 599.0
PYH1_k127_6732360_11 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 589.0
PYH1_k127_6732360_12 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 576.0
PYH1_k127_6732360_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 559.0
PYH1_k127_6732360_14 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
PYH1_k127_6732360_15 TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 492.0
PYH1_k127_6732360_16 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 498.0
PYH1_k127_6732360_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 495.0
PYH1_k127_6732360_18 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 481.0
PYH1_k127_6732360_19 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 471.0
PYH1_k127_6732360_2 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.819e-240 751.0
PYH1_k127_6732360_20 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 463.0
PYH1_k127_6732360_21 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 465.0
PYH1_k127_6732360_22 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 436.0
PYH1_k127_6732360_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
PYH1_k127_6732360_24 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 366.0
PYH1_k127_6732360_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
PYH1_k127_6732360_26 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
PYH1_k127_6732360_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
PYH1_k127_6732360_28 Two component transcriptional regulator K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 288.0
PYH1_k127_6732360_29 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
PYH1_k127_6732360_3 Prolyl oligopeptidase family - - - 1.758e-229 730.0
PYH1_k127_6732360_30 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH1_k127_6732360_31 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000001126 258.0
PYH1_k127_6732360_32 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003997 238.0
PYH1_k127_6732360_33 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001111 248.0
PYH1_k127_6732360_34 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
PYH1_k127_6732360_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
PYH1_k127_6732360_36 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004096 240.0
PYH1_k127_6732360_37 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000005142 222.0
PYH1_k127_6732360_38 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000007372 212.0
PYH1_k127_6732360_39 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000006204 183.0
PYH1_k127_6732360_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.261e-229 715.0
PYH1_k127_6732360_40 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000007442 171.0
PYH1_k127_6732360_41 - - - - 0.00000000000000000000000000000000000000000002329 172.0
PYH1_k127_6732360_42 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000002874 178.0
PYH1_k127_6732360_43 - - - - 0.000000000000000000000000000000000000000003975 164.0
PYH1_k127_6732360_44 Lecithin retinol acyltransferase - - - 0.0000000000000000000000000000000000000002279 158.0
PYH1_k127_6732360_45 Cyclase dehydrase - - - 0.000000000000000000000000000000000000002239 159.0
PYH1_k127_6732360_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000003703 122.0
PYH1_k127_6732360_47 - - - - 0.000000000000000000000000001772 119.0
PYH1_k127_6732360_48 - - - - 0.00000000000000000000000742 106.0
PYH1_k127_6732360_49 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000007732 102.0
PYH1_k127_6732360_5 TRAP dicarboxylate transporter, DctM subunit K11690 - - 3.936e-222 696.0
PYH1_k127_6732360_50 Domain of unknown function (DUF1840) - - - 0.00000000000000041 82.0
PYH1_k127_6732360_51 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000006068 75.0
PYH1_k127_6732360_6 Sulfatase - - - 7.727e-219 692.0
PYH1_k127_6732360_7 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.931e-208 655.0
PYH1_k127_6732360_8 von Willebrand factor, type A K07114 - - 1.351e-204 656.0
PYH1_k127_6732360_9 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 8.557e-197 626.0
PYH1_k127_6749206_0 synthetase K01907 - 6.2.1.16 1.101e-285 892.0
PYH1_k127_6749206_1 PFAM MmgE PrpD family protein - - - 7.074e-231 722.0
PYH1_k127_6749206_10 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 407.0
PYH1_k127_6749206_11 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 400.0
PYH1_k127_6749206_12 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 373.0
PYH1_k127_6749206_13 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 368.0
PYH1_k127_6749206_14 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 354.0
PYH1_k127_6749206_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
PYH1_k127_6749206_16 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 291.0
PYH1_k127_6749206_17 Kelch - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008038 258.0
PYH1_k127_6749206_18 - - - - 0.000000000000000000000000000000000000000000000000000000003016 208.0
PYH1_k127_6749206_19 - - - - 0.00000000000000000000000000000000000000000008344 168.0
PYH1_k127_6749206_2 ABC transporter C-terminal domain K15738 - - 3.691e-230 729.0
PYH1_k127_6749206_20 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000002007 151.0
PYH1_k127_6749206_21 BON domain - - - 0.00000000000000000000000000000000000034 156.0
PYH1_k127_6749206_22 transcriptional regulator - - - 0.000000000000000000000000000000000001039 151.0
PYH1_k127_6749206_23 Glycine-zipper domain - - - 0.00000000000000000000000000000000001811 143.0
PYH1_k127_6749206_24 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000004861 122.0
PYH1_k127_6749206_25 - - - - 0.000000000000000000000769 100.0
PYH1_k127_6749206_26 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000518 72.0
PYH1_k127_6749206_27 Protein of unknown function (DUF3144) - - - 0.00000002376 67.0
PYH1_k127_6749206_28 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0003683 45.0
PYH1_k127_6749206_3 cytosine deaminase K01485 - 3.5.4.1 3.06e-228 711.0
PYH1_k127_6749206_4 Ammonium Transporter Family K03320,K06580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 599.0
PYH1_k127_6749206_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 481.0
PYH1_k127_6749206_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
PYH1_k127_6749206_7 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 440.0
PYH1_k127_6749206_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 430.0
PYH1_k127_6749206_9 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 431.0
PYH1_k127_6753715_0 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
PYH1_k127_6753715_1 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.0000000000000000000000000000001048 127.0
PYH1_k127_6753715_2 Domain of unknown function (DUF1850) - - - 0.000000000000000003878 89.0
PYH1_k127_6762395_0 Transketolase, pyrimidine binding domain K21417 - - 1.393e-194 609.0
PYH1_k127_6762395_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
PYH1_k127_6762395_2 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 547.0
PYH1_k127_6762395_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 532.0
PYH1_k127_6762395_4 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 486.0
PYH1_k127_6762395_5 lipoate-protein ligase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 252.0
PYH1_k127_6762395_6 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000005754 156.0
PYH1_k127_6762395_7 - - - - 0.00000000000003941 74.0
PYH1_k127_6773840_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1059.0
PYH1_k127_6773840_1 GGDEF domain - - - 1.449e-311 976.0
PYH1_k127_6773840_2 GGDEF domain - - - 3.815e-286 903.0
PYH1_k127_6773840_3 GGDEF domain - - - 8.246e-286 904.0
PYH1_k127_6773840_4 Subtilase family - - - 8.024e-259 821.0
PYH1_k127_6773840_5 Subtilase family - - - 1.175e-220 704.0
PYH1_k127_6773840_6 Subtilase family - - - 1.939e-220 707.0
PYH1_k127_6773840_7 Protein of unknown function, DUF480 - - - 0.0000000000000000000000000000000000000000000000000000000000005215 219.0
PYH1_k127_6773840_8 CBS domain - - - 0.0000000000000000000000000000008658 132.0
PYH1_k127_6785336_0 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 299.0
PYH1_k127_6785336_1 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000006965 226.0
PYH1_k127_6785336_2 - - - - 0.000000000000000000000000000000000000000000000000000008685 193.0
PYH1_k127_6785336_3 DsrC like protein K11179 - - 0.000000000000000000000000000000000000007504 151.0
PYH1_k127_6785336_4 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000004251 144.0
PYH1_k127_6785336_5 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000000002702 144.0
PYH1_k127_6802411_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.124e-240 752.0
PYH1_k127_6802411_1 Aldehyde dehydrogenase family K15514 - 1.2.1.77 3.538e-215 679.0
PYH1_k127_6802411_2 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 526.0
PYH1_k127_6802411_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 396.0
PYH1_k127_6802411_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 374.0
PYH1_k127_6802411_5 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
PYH1_k127_6802411_6 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000000001372 229.0
PYH1_k127_6802830_0 ABC transporter transmembrane region K06147 - - 4.423e-274 862.0
PYH1_k127_6802830_1 FAD dependent oxidoreductase K07256 - - 7.103e-255 791.0
PYH1_k127_6802830_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 571.0
PYH1_k127_6802830_3 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
PYH1_k127_6802830_4 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0000000000000000000000000000000000000000000004928 169.0
PYH1_k127_6802830_5 MAPEG family - - - 0.0000000000000000000000000000000000001411 147.0
PYH1_k127_6802830_6 Lipocalin-like domain - - - 0.00000001711 55.0
PYH1_k127_6813471_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.895e-226 719.0
PYH1_k127_6813471_1 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 524.0
PYH1_k127_6813471_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 322.0
PYH1_k127_6813471_11 Pfam Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 311.0
PYH1_k127_6813471_12 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 304.0
PYH1_k127_6813471_13 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
PYH1_k127_6813471_14 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 306.0
PYH1_k127_6813471_15 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
PYH1_k127_6813471_16 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000008087 220.0
PYH1_k127_6813471_17 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
PYH1_k127_6813471_18 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000000000000000000000000000000002392 192.0
PYH1_k127_6813471_19 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000007785 178.0
PYH1_k127_6813471_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 511.0
PYH1_k127_6813471_20 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000006333 158.0
PYH1_k127_6813471_21 cell division protein - - - 0.000000000000000000000000000006914 127.0
PYH1_k127_6813471_22 - - - - 0.000000000000000000000000002239 120.0
PYH1_k127_6813471_23 exo-alpha-(2->6)-sialidase activity K01179,K01186,K12373,K17624 - 3.2.1.18,3.2.1.4,3.2.1.52,3.2.1.97 0.000000000000001908 78.0
PYH1_k127_6813471_3 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 507.0
PYH1_k127_6813471_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 490.0
PYH1_k127_6813471_5 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 388.0
PYH1_k127_6813471_6 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 343.0
PYH1_k127_6813471_7 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
PYH1_k127_6813471_8 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 336.0
PYH1_k127_6813471_9 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 323.0
PYH1_k127_6814646_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 6.798e-209 682.0
PYH1_k127_6814646_1 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 423.0
PYH1_k127_6814646_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
PYH1_k127_6814646_4 transcriptional regulators K03892 - - 0.000000000000000000000000000000000000486 143.0
PYH1_k127_6814646_5 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000002538 115.0
PYH1_k127_6814646_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000006193 82.0
PYH1_k127_6814646_7 NHL repeat - - - 0.000000000000009587 85.0
PYH1_k127_6814646_8 PFAM UvrB UvrC protein - - - 0.000001354 59.0
PYH1_k127_6836976_0 AMP-binding enzyme C-terminal domain - - - 2.602e-229 720.0
PYH1_k127_6836976_1 AMP-binding enzyme C-terminal domain K18661 - - 4.052e-217 686.0
PYH1_k127_6836976_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000001595 199.0
PYH1_k127_6836976_11 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000001148 194.0
PYH1_k127_6836976_12 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000001808 143.0
PYH1_k127_6836976_13 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000001347 128.0
PYH1_k127_6836976_14 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000003478 97.0
PYH1_k127_6836976_15 - - - - 0.000611 46.0
PYH1_k127_6836976_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 445.0
PYH1_k127_6836976_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 437.0
PYH1_k127_6836976_4 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 413.0
PYH1_k127_6836976_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 384.0
PYH1_k127_6836976_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
PYH1_k127_6836976_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005869 279.0
PYH1_k127_6836976_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005282 258.0
PYH1_k127_6836976_9 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001311 229.0
PYH1_k127_6856224_0 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 318.0
PYH1_k127_6856224_1 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000003815 206.0
PYH1_k127_6856224_2 PIN domain - - - 0.000000000000000000000000000000000000000000006191 170.0
PYH1_k127_6856224_3 toxin-antitoxin pair type II binding K19156 GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000002674 128.0
PYH1_k127_6856224_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000007866 109.0
PYH1_k127_6883965_0 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 447.0
PYH1_k127_6883965_1 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 418.0
PYH1_k127_6883965_2 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 362.0
PYH1_k127_6883965_3 Transposase DDE domain group 1 - - - 0.000000000000000001202 85.0
PYH1_k127_6883965_4 reverse transcriptase - - - 0.00000000000003796 75.0
PYH1_k127_6883965_5 Transposase DDE domain group 1 - - - 0.0000000007917 63.0
PYH1_k127_6883965_6 reverse transcriptase - - - 0.0000002875 54.0
PYH1_k127_6883965_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00003284 48.0
PYH1_k127_6904665_0 Histidine ammonia-lyase K01745 - 4.3.1.3 8.949e-200 634.0
PYH1_k127_6904665_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 512.0
PYH1_k127_6904665_2 glycine betaine K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 460.0
PYH1_k127_6904665_3 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 380.0
PYH1_k127_6904665_4 ABC-type proline glycine betaine transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
PYH1_k127_6904665_5 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000132 263.0
PYH1_k127_6904665_6 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000000000005073 225.0
PYH1_k127_6909132_0 4Fe-4S dicluster domain K18930 - - 0.0 1131.0
PYH1_k127_6909132_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 537.0
PYH1_k127_6909132_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
PYH1_k127_6909132_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 430.0
PYH1_k127_6909132_4 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 312.0
PYH1_k127_6909132_5 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000000000000000000004339 212.0
PYH1_k127_6909132_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000002086 205.0
PYH1_k127_6909132_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000004853 185.0
PYH1_k127_6909132_8 - - - - 0.0000000000000000000000161 108.0
PYH1_k127_6936080_0 Tricorn protease homolog K08676 - - 0.0 1104.0
PYH1_k127_6936080_1 Male sterility protein - - - 0.0 1005.0
PYH1_k127_6936080_10 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 550.0
PYH1_k127_6936080_11 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 511.0
PYH1_k127_6936080_12 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 499.0
PYH1_k127_6936080_13 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 489.0
PYH1_k127_6936080_14 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
PYH1_k127_6936080_15 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 433.0
PYH1_k127_6936080_16 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 430.0
PYH1_k127_6936080_17 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 405.0
PYH1_k127_6936080_18 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 398.0
PYH1_k127_6936080_19 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 366.0
PYH1_k127_6936080_2 Molecular chaperone. Has ATPase activity K04079 - - 9.247e-299 927.0
PYH1_k127_6936080_20 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 345.0
PYH1_k127_6936080_21 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 323.0
PYH1_k127_6936080_22 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 324.0
PYH1_k127_6936080_23 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 326.0
PYH1_k127_6936080_24 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
PYH1_k127_6936080_25 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 319.0
PYH1_k127_6936080_26 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 312.0
PYH1_k127_6936080_27 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 293.0
PYH1_k127_6936080_28 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007586 279.0
PYH1_k127_6936080_29 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
PYH1_k127_6936080_3 ABC-type Fe3 transport system permease component K02011 - - 2.159e-250 788.0
PYH1_k127_6936080_30 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001766 269.0
PYH1_k127_6936080_31 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005522 268.0
PYH1_k127_6936080_32 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002709 265.0
PYH1_k127_6936080_33 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
PYH1_k127_6936080_34 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
PYH1_k127_6936080_35 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
PYH1_k127_6936080_36 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000004204 251.0
PYH1_k127_6936080_37 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000005363 251.0
PYH1_k127_6936080_38 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000002047 246.0
PYH1_k127_6936080_39 glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
PYH1_k127_6936080_4 Branched-chain amino acid transport system / permease component K01997,K01998 - - 6.974e-211 671.0
PYH1_k127_6936080_40 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH1_k127_6936080_41 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000002359 209.0
PYH1_k127_6936080_42 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000004909 200.0
PYH1_k127_6936080_43 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000004192 206.0
PYH1_k127_6936080_44 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000001531 180.0
PYH1_k127_6936080_45 PFAM poly granule associated family protein - - - 0.000000000000000000000000000000000000002323 152.0
PYH1_k127_6936080_46 Copper resistance protein D - - - 0.0000000000000000000000000000000001429 137.0
PYH1_k127_6936080_47 acyl-coA-binding protein - - - 0.000000000000000000000000000000000322 134.0
PYH1_k127_6936080_48 Cytochrome c - - - 0.00000000000000000000000000003538 121.0
PYH1_k127_6936080_49 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000001563 120.0
PYH1_k127_6936080_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 6.349e-203 640.0
PYH1_k127_6936080_50 Cytochrome c, class I - - - 0.0000000000000000000000000002593 117.0
PYH1_k127_6936080_51 - - - - 0.000000000000000000000004775 111.0
PYH1_k127_6936080_52 DDE superfamily endonuclease K07494 - - 0.000000000000000004882 90.0
PYH1_k127_6936080_53 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000001207 86.0
PYH1_k127_6936080_54 - - - - 0.0000000000004358 72.0
PYH1_k127_6936080_55 Receptor family ligand binding region K01999 - - 0.0000000004018 67.0
PYH1_k127_6936080_6 ABC-type Fe3 transport system, periplasmic component - - - 5.145e-196 620.0
PYH1_k127_6936080_7 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 601.0
PYH1_k127_6936080_8 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 592.0
PYH1_k127_6936080_9 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 577.0
PYH1_k127_6981163_0 Histidine kinase-like ATPases - - - 2.874e-318 1067.0
PYH1_k127_6982310_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1667.0
PYH1_k127_6982310_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1048.0
PYH1_k127_6982310_10 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001483 233.0
PYH1_k127_6982310_11 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000001165 133.0
PYH1_k127_6982310_12 - - - - 0.00000000000000000000000000006189 124.0
PYH1_k127_6982310_13 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000002132 89.0
PYH1_k127_6982310_2 Fe-S oxidoreductase K21834 - - 4.744e-280 870.0
PYH1_k127_6982310_3 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 564.0
PYH1_k127_6982310_4 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 486.0
PYH1_k127_6982310_5 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
PYH1_k127_6982310_6 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 406.0
PYH1_k127_6982310_7 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 398.0
PYH1_k127_6982310_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
PYH1_k127_6982310_9 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001494 258.0
PYH1_k127_6995527_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 2.131e-234 787.0
PYH1_k127_6995527_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000007058 143.0
PYH1_k127_7024802_0 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 334.0
PYH1_k127_7024802_1 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005018 267.0
PYH1_k127_7024802_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000003884 237.0
PYH1_k127_7024802_3 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000004144 102.0
PYH1_k127_7029178_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1212.0
PYH1_k127_7029178_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1124.0
PYH1_k127_7029178_10 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 500.0
PYH1_k127_7029178_11 C-terminal region of band_7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
PYH1_k127_7029178_12 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 466.0
PYH1_k127_7029178_13 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 449.0
PYH1_k127_7029178_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 437.0
PYH1_k127_7029178_15 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 443.0
PYH1_k127_7029178_16 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 421.0
PYH1_k127_7029178_17 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 410.0
PYH1_k127_7029178_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 398.0
PYH1_k127_7029178_19 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 403.0
PYH1_k127_7029178_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 5e-324 1015.0
PYH1_k127_7029178_20 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 419.0
PYH1_k127_7029178_21 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 395.0
PYH1_k127_7029178_22 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 387.0
PYH1_k127_7029178_23 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 380.0
PYH1_k127_7029178_24 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 368.0
PYH1_k127_7029178_25 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
PYH1_k127_7029178_26 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 345.0
PYH1_k127_7029178_27 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
PYH1_k127_7029178_28 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 335.0
PYH1_k127_7029178_29 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 318.0
PYH1_k127_7029178_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.452e-289 902.0
PYH1_k127_7029178_30 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 283.0
PYH1_k127_7029178_31 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 273.0
PYH1_k127_7029178_32 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
PYH1_k127_7029178_33 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000136 232.0
PYH1_k127_7029178_34 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000009085 233.0
PYH1_k127_7029178_35 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
PYH1_k127_7029178_36 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000002201 209.0
PYH1_k127_7029178_37 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000003568 196.0
PYH1_k127_7029178_38 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000007189 184.0
PYH1_k127_7029178_39 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000001066 161.0
PYH1_k127_7029178_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.486e-286 899.0
PYH1_k127_7029178_40 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000003718 162.0
PYH1_k127_7029178_41 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000149 152.0
PYH1_k127_7029178_42 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000872 132.0
PYH1_k127_7029178_43 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000002147 131.0
PYH1_k127_7029178_44 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000003088 83.0
PYH1_k127_7029178_45 Domain of unknown function (DUF4124) - - - 0.00000000000000003639 90.0
PYH1_k127_7029178_46 Protein of unknown function (DUF1847) - - - 0.00000000000000004417 88.0
PYH1_k127_7029178_47 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000001194 75.0
PYH1_k127_7029178_48 Protein of unknown function (DUF1847) - - - 0.000000001951 62.0
PYH1_k127_7029178_5 ABC transporter C-terminal domain K06158 - - 1.948e-260 816.0
PYH1_k127_7029178_50 Protein of unknown function (DUF1847) - - - 0.0005809 42.0
PYH1_k127_7029178_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.983e-241 755.0
PYH1_k127_7029178_7 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 528.0
PYH1_k127_7029178_8 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 526.0
PYH1_k127_7029178_9 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
PYH1_k127_7030827_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1008.0
PYH1_k127_7030827_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 514.0
PYH1_k127_7030827_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 451.0
PYH1_k127_7030827_3 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 430.0
PYH1_k127_7030827_4 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 426.0
PYH1_k127_7030827_5 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
PYH1_k127_7030827_6 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
PYH1_k127_7030827_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
PYH1_k127_7030827_8 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 324.0
PYH1_k127_7030827_9 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000001999 142.0
PYH1_k127_7059254_0 PFAM Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 395.0
PYH1_k127_7059254_1 MbtH-like protein K05375 - - 0.00001745 50.0
PYH1_k127_70664_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0 1203.0
PYH1_k127_70664_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1041.0
PYH1_k127_70664_10 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 447.0
PYH1_k127_70664_11 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 393.0
PYH1_k127_70664_12 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
PYH1_k127_70664_13 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 371.0
PYH1_k127_70664_14 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 364.0
PYH1_k127_70664_15 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 345.0
PYH1_k127_70664_16 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
PYH1_k127_70664_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 343.0
PYH1_k127_70664_18 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
PYH1_k127_70664_19 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 325.0
PYH1_k127_70664_2 Phosphopantetheine attachment site - - - 3.917e-270 862.0
PYH1_k127_70664_20 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 313.0
PYH1_k127_70664_21 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
PYH1_k127_70664_22 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002674 265.0
PYH1_k127_70664_23 Prokaryotic cytochrome b561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
PYH1_k127_70664_24 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
PYH1_k127_70664_25 Electron transfer DM13 - - - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
PYH1_k127_70664_26 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
PYH1_k127_70664_27 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000136 222.0
PYH1_k127_70664_28 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000002669 203.0
PYH1_k127_70664_29 succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000397 197.0
PYH1_k127_70664_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.635e-269 837.0
PYH1_k127_70664_30 - - - - 0.000000000000000000000000000000000000000000002854 168.0
PYH1_k127_70664_31 Nitroreductase family - - - 0.000000000000000000000000000000000000000000003303 171.0
PYH1_k127_70664_32 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001043 167.0
PYH1_k127_70664_33 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000002671 152.0
PYH1_k127_70664_34 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000002339 150.0
PYH1_k127_70664_35 Universal stress protein - - - 0.000000000000000000000000000000000001658 143.0
PYH1_k127_70664_36 GYD domain - - - 0.0000000000000000000000000000000000258 138.0
PYH1_k127_70664_37 - - - - 0.0000000000000000000000000000001586 130.0
PYH1_k127_70664_38 Protein of unknown function (DUF504) - - - 0.00000000000000000000000003902 110.0
PYH1_k127_70664_39 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000009877 108.0
PYH1_k127_70664_4 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 4.042e-216 679.0
PYH1_k127_70664_40 Protein of unknown function DUF86 - - - 0.000000000000000000000001366 109.0
PYH1_k127_70664_41 - - - - 0.000000000000000000001276 97.0
PYH1_k127_70664_42 - - - - 0.00000000000000001165 83.0
PYH1_k127_70664_44 Transcriptional regulator - - - 0.0001273 45.0
PYH1_k127_70664_5 protein containing a von Willebrand factor type A (vWA) domain - - - 8.537e-215 677.0
PYH1_k127_70664_6 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 586.0
PYH1_k127_70664_7 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 572.0
PYH1_k127_70664_8 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 571.0
PYH1_k127_70664_9 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 473.0
PYH1_k127_7150469_0 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 315.0
PYH1_k127_7150469_1 Glycosyl transferases group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 306.0
PYH1_k127_7289646_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 602.0
PYH1_k127_7289646_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 479.0
PYH1_k127_7289646_10 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000003749 152.0
PYH1_k127_7289646_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000005241 158.0
PYH1_k127_7289646_12 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000003937 138.0
PYH1_k127_7289646_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000007239 124.0
PYH1_k127_7289646_14 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000001513 106.0
PYH1_k127_7289646_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 462.0
PYH1_k127_7289646_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
PYH1_k127_7289646_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
PYH1_k127_7289646_5 Biopolymer transport K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
PYH1_k127_7289646_6 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
PYH1_k127_7289646_7 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000009101 229.0
PYH1_k127_7289646_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
PYH1_k127_7289646_9 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000000003469 156.0
PYH1_k127_7307132_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 1.146e-263 834.0
PYH1_k127_7307132_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 2.581e-231 727.0
PYH1_k127_7307132_10 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000004587 188.0
PYH1_k127_7307132_11 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000001616 179.0
PYH1_k127_7307132_12 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000001234 185.0
PYH1_k127_7307132_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000005639 148.0
PYH1_k127_7307132_14 ASCH - - - 0.000000000000000000000000000000000001234 145.0
PYH1_k127_7307132_15 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000007164 142.0
PYH1_k127_7307132_16 Uncharacterized protein conserved in bacteria (DUF2332) K01056 - 3.1.1.29 0.00000000003332 68.0
PYH1_k127_7307132_17 Galactose binding lectin domain - - - 0.00000005661 60.0
PYH1_k127_7307132_18 DnaJ domain protein - - - 0.0004557 49.0
PYH1_k127_7307132_2 dehydrogenase K00253 - 1.3.8.4 5.372e-222 692.0
PYH1_k127_7307132_3 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 8.807e-222 706.0
PYH1_k127_7307132_4 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 444.0
PYH1_k127_7307132_5 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 430.0
PYH1_k127_7307132_6 Cys/Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 416.0
PYH1_k127_7307132_7 threonine dehydratase K17989 GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 362.0
PYH1_k127_7307132_8 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000828 289.0
PYH1_k127_7307132_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001382 205.0
PYH1_k127_7371839_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1690.0
PYH1_k127_7371839_1 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 602.0
PYH1_k127_7371839_10 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 314.0
PYH1_k127_7371839_11 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000005466 244.0
PYH1_k127_7371839_12 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
PYH1_k127_7371839_13 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000002885 165.0
PYH1_k127_7371839_14 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000127 150.0
PYH1_k127_7371839_15 Adenylate cyclase - - - 0.000000000000000000000000000000000000401 148.0
PYH1_k127_7371839_16 TIGRFAM phasin family protein - - - 0.00000000000000000000000000000000001019 143.0
PYH1_k127_7371839_17 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000008617 150.0
PYH1_k127_7371839_18 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000004269 117.0
PYH1_k127_7371839_19 - - - - 0.0000000000000000000007265 104.0
PYH1_k127_7371839_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 601.0
PYH1_k127_7371839_20 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000002551 73.0
PYH1_k127_7371839_21 DDE superfamily endonuclease - - - 0.0000000001243 62.0
PYH1_k127_7371839_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 462.0
PYH1_k127_7371839_4 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
PYH1_k127_7371839_5 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 382.0
PYH1_k127_7371839_6 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
PYH1_k127_7371839_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
PYH1_k127_7371839_8 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 353.0
PYH1_k127_7371839_9 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 332.0
PYH1_k127_7424376_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.803e-282 876.0
PYH1_k127_7424376_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 4.759e-258 820.0
PYH1_k127_7424376_10 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 457.0
PYH1_k127_7424376_11 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 432.0
PYH1_k127_7424376_12 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 427.0
PYH1_k127_7424376_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 392.0
PYH1_k127_7424376_14 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
PYH1_k127_7424376_15 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 334.0
PYH1_k127_7424376_16 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 307.0
PYH1_k127_7424376_17 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
PYH1_k127_7424376_18 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000000000000006536 211.0
PYH1_k127_7424376_19 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000004557 161.0
PYH1_k127_7424376_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.083e-215 680.0
PYH1_k127_7424376_20 DNA mediated transformation - - - 0.000000000000000000000000000000000001278 147.0
PYH1_k127_7424376_21 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000001524 131.0
PYH1_k127_7424376_22 FMN binding - - - 0.0000000000000000000000000000006389 128.0
PYH1_k127_7424376_23 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000002495 105.0
PYH1_k127_7424376_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000002089 102.0
PYH1_k127_7424376_25 Phosphopantetheine attachment site - - - 0.000000000000000005392 94.0
PYH1_k127_7424376_26 membrane - - - 0.000000001312 64.0
PYH1_k127_7424376_27 - - - - 0.000004923 53.0
PYH1_k127_7424376_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 554.0
PYH1_k127_7424376_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 539.0
PYH1_k127_7424376_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 526.0
PYH1_k127_7424376_6 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 503.0
PYH1_k127_7424376_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 503.0
PYH1_k127_7424376_8 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 485.0
PYH1_k127_7424376_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 469.0
PYH1_k127_7448321_0 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 437.0
PYH1_k127_7448321_1 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 392.0
PYH1_k127_7448321_10 PFAM Major facilitator superfamily K02575 - - 0.00000000000000001185 87.0
PYH1_k127_7448321_2 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 375.0
PYH1_k127_7448321_3 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 297.0
PYH1_k127_7448321_4 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
PYH1_k127_7448321_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
PYH1_k127_7448321_6 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
PYH1_k127_7448321_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006918 171.0
PYH1_k127_7448321_8 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000002096 108.0
PYH1_k127_7448321_9 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000002215 93.0
PYH1_k127_7561319_0 DNA polymerase X family K02347 - - 2.445e-234 737.0
PYH1_k127_7561319_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 429.0
PYH1_k127_7561319_10 - - - - 0.00000000000000001153 88.0
PYH1_k127_7561319_11 - - - - 0.000000000155 67.0
PYH1_k127_7561319_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
PYH1_k127_7561319_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 289.0
PYH1_k127_7561319_4 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003614 243.0
PYH1_k127_7561319_5 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
PYH1_k127_7561319_6 cystathionine K01758 - 4.4.1.1 0.000000000000000000000000000000000000001092 151.0
PYH1_k127_7561319_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000003584 145.0
PYH1_k127_7561319_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000004004 138.0
PYH1_k127_7561319_9 response regulator - - - 0.000000000000000000000000008568 124.0
PYH1_k127_7571724_0 TRAP dicarboxylate transporter, DctM subunit K03299 - - 1.508e-258 808.0
PYH1_k127_7571724_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 582.0
PYH1_k127_7571724_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 549.0
PYH1_k127_7571724_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 379.0
PYH1_k127_7571724_4 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
PYH1_k127_7571724_5 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 294.0
PYH1_k127_7571724_6 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
PYH1_k127_7571724_7 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000000004069 163.0
PYH1_k127_7571724_8 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000003361 147.0
PYH1_k127_7571724_9 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000463 139.0
PYH1_k127_7579346_0 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 496.0
PYH1_k127_7579346_1 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 477.0
PYH1_k127_7579346_2 PFAM extracellular solute-binding protein family 1 K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 428.0
PYH1_k127_7579346_3 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 385.0
PYH1_k127_7582438_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1065.0
PYH1_k127_7582438_1 Histidine kinase - - - 0.0000000000000000000000000000000000001971 144.0
PYH1_k127_7607410_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 372.0
PYH1_k127_7607410_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 335.0
PYH1_k127_7607410_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000248 232.0
PYH1_k127_7607410_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000001669 171.0
PYH1_k127_7607410_12 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000002477 171.0
PYH1_k127_7607410_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000018 171.0
PYH1_k127_7607410_14 - - - - 0.00000000000000000000000000000000258 131.0
PYH1_k127_7607410_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000009947 63.0
PYH1_k127_7607410_16 Domain of unknown function (DUF4936) - - - 0.0000002636 56.0
PYH1_k127_7607410_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 319.0
PYH1_k127_7607410_3 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001424 283.0
PYH1_k127_7607410_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000192 271.0
PYH1_k127_7607410_5 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000126 258.0
PYH1_k127_7607410_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000005441 248.0
PYH1_k127_7607410_7 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006825 247.0
PYH1_k127_7607410_8 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
PYH1_k127_7607410_9 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
PYH1_k127_7620095_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 446.0
PYH1_k127_7620095_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 384.0
PYH1_k127_7620095_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 323.0
PYH1_k127_7620095_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 301.0
PYH1_k127_7633368_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 518.0
PYH1_k127_7633368_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000001401 176.0
PYH1_k127_7638750_0 Ketopantoate hydroxymethyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 494.0
PYH1_k127_7638750_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 377.0
PYH1_k127_7638750_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 354.0
PYH1_k127_7638750_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 266.0
PYH1_k127_7638750_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000001831 239.0
PYH1_k127_7638750_5 COG1145 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000001259 213.0
PYH1_k127_7638750_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000009582 100.0
PYH1_k127_7645040_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 7.63e-214 679.0
PYH1_k127_7645040_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 417.0
PYH1_k127_7645040_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 398.0
PYH1_k127_7657359_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 5.814e-262 813.0
PYH1_k127_7657359_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 2.477e-211 660.0
PYH1_k127_7657359_2 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 9.726e-202 633.0
PYH1_k127_7657359_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 540.0
PYH1_k127_7657359_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 496.0
PYH1_k127_7657359_5 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 473.0
PYH1_k127_7657359_6 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000003401 75.0
PYH1_k127_7666430_0 PIN domain - - - 0.000000000000000000000000000008576 126.0
PYH1_k127_7666430_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000001332 94.0
PYH1_k127_7675098_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.302e-304 938.0
PYH1_k127_7675098_1 PrkA AAA domain K07180 - - 8.929e-275 859.0
PYH1_k127_7675098_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 547.0
PYH1_k127_7675098_11 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 526.0
PYH1_k127_7675098_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 518.0
PYH1_k127_7675098_13 Cobalamin biosynthesis protein CobW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 510.0
PYH1_k127_7675098_14 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 508.0
PYH1_k127_7675098_15 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 499.0
PYH1_k127_7675098_16 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 477.0
PYH1_k127_7675098_17 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 469.0
PYH1_k127_7675098_18 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 463.0
PYH1_k127_7675098_19 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
PYH1_k127_7675098_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.716e-256 810.0
PYH1_k127_7675098_20 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 426.0
PYH1_k127_7675098_21 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 422.0
PYH1_k127_7675098_22 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 414.0
PYH1_k127_7675098_23 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 422.0
PYH1_k127_7675098_24 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 404.0
PYH1_k127_7675098_25 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 407.0
PYH1_k127_7675098_26 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
PYH1_k127_7675098_27 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 388.0
PYH1_k127_7675098_28 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 402.0
PYH1_k127_7675098_29 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
PYH1_k127_7675098_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.618e-227 711.0
PYH1_k127_7675098_30 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
PYH1_k127_7675098_31 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
PYH1_k127_7675098_32 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
PYH1_k127_7675098_33 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 322.0
PYH1_k127_7675098_34 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
PYH1_k127_7675098_35 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 299.0
PYH1_k127_7675098_36 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 284.0
PYH1_k127_7675098_37 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
PYH1_k127_7675098_38 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007148 265.0
PYH1_k127_7675098_39 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH1_k127_7675098_4 protein related to plant photosystem II stability assembly factor - - - 1.632e-218 683.0
PYH1_k127_7675098_40 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000004334 265.0
PYH1_k127_7675098_41 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001886 272.0
PYH1_k127_7675098_42 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000001709 248.0
PYH1_k127_7675098_43 cytochrome C oxidase K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
PYH1_k127_7675098_44 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006564 243.0
PYH1_k127_7675098_45 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000001792 252.0
PYH1_k127_7675098_46 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000002866 240.0
PYH1_k127_7675098_47 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
PYH1_k127_7675098_48 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
PYH1_k127_7675098_49 Hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
PYH1_k127_7675098_5 Peptidase family S49 K04773 - - 7.421e-216 687.0
PYH1_k127_7675098_50 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001489 225.0
PYH1_k127_7675098_51 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
PYH1_k127_7675098_52 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000005632 224.0
PYH1_k127_7675098_53 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
PYH1_k127_7675098_54 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000001276 194.0
PYH1_k127_7675098_55 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000006593 190.0
PYH1_k127_7675098_56 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000002118 196.0
PYH1_k127_7675098_57 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000007444 175.0
PYH1_k127_7675098_58 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000002451 178.0
PYH1_k127_7675098_59 SURF1-like protein - - - 0.0000000000000000000000000000000000000000000002174 178.0
PYH1_k127_7675098_6 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.806e-211 665.0
PYH1_k127_7675098_60 Lysin motif - - - 0.000000000000000000000000000000000000000000005261 165.0
PYH1_k127_7675098_61 Type II secretory pathway, component - - - 0.00000000000000000000000000000000000000000108 167.0
PYH1_k127_7675098_62 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000005765 167.0
PYH1_k127_7675098_63 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000009081 152.0
PYH1_k127_7675098_64 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000001404 140.0
PYH1_k127_7675098_65 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000004231 145.0
PYH1_k127_7675098_66 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000002025 136.0
PYH1_k127_7675098_67 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000007155 134.0
PYH1_k127_7675098_68 ThiS family K03636 - - 0.000000000000000000000000000000006969 128.0
PYH1_k127_7675098_69 CoA binding domain - - - 0.0000000000000000000000000000009727 130.0
PYH1_k127_7675098_7 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 564.0
PYH1_k127_7675098_70 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000001775 111.0
PYH1_k127_7675098_71 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000000006442 104.0
PYH1_k127_7675098_72 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000001097 100.0
PYH1_k127_7675098_73 Protein of unknown function (DUF2970) - - - 0.000000000000000001085 91.0
PYH1_k127_7675098_74 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000005529 86.0
PYH1_k127_7675098_75 Protein of unknown function (DUF2909) - - - 0.0000000000002573 75.0
PYH1_k127_7675098_76 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000003772 68.0
PYH1_k127_7675098_77 mercury ion transmembrane transporter activity - - - 0.0000000008497 64.0
PYH1_k127_7675098_79 - - - - 0.00004768 52.0
PYH1_k127_7675098_8 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 563.0
PYH1_k127_7675098_80 - - - - 0.0002845 51.0
PYH1_k127_7675098_81 Lysin motif - - - 0.000695 46.0
PYH1_k127_7675098_9 SpoVR family K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 556.0
PYH1_k127_7676089_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0 1231.0
PYH1_k127_7676089_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.792e-242 750.0
PYH1_k127_7676089_10 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000006282 186.0
PYH1_k127_7676089_11 - - - - 0.0000000000000000000000000000000000000005495 150.0
PYH1_k127_7676089_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000006223 161.0
PYH1_k127_7676089_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 515.0
PYH1_k127_7676089_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 498.0
PYH1_k127_7676089_4 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 483.0
PYH1_k127_7676089_5 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 434.0
PYH1_k127_7676089_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 369.0
PYH1_k127_7676089_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 374.0
PYH1_k127_7676089_8 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
PYH1_k127_7676089_9 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 334.0
PYH1_k127_7683390_0 FAD dependent oxidoreductase K13796 - - 5.943e-236 736.0
PYH1_k127_7683390_1 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 4.461e-216 682.0
PYH1_k127_7683390_2 CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 610.0
PYH1_k127_7683390_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001346 269.0
PYH1_k127_7683390_4 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 261.0
PYH1_k127_7683390_5 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000265 246.0
PYH1_k127_7683390_6 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
PYH1_k127_7690657_0 GMC oxidoreductase K00108 - 1.1.99.1 6.486e-224 703.0
PYH1_k127_7690657_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 560.0
PYH1_k127_7690657_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 421.0
PYH1_k127_7690657_3 PFAM CHRD domain containing protein - - - 0.00000000000000001038 91.0
PYH1_k127_7691048_0 PFAM transposase, IS111A IS1328 IS1533 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 481.0
PYH1_k127_7691048_1 IS66 C-terminal element - - - 0.0000000000000000000000000000000000000000000000000000000003147 209.0
PYH1_k127_7691048_2 COG3436 Transposase and inactivated derivatives K07484 - - 0.00000000000000000000000000000000000000000000001536 178.0
PYH1_k127_7691048_3 IS66 C-terminal element - - - 0.000000000000000000000000000001836 122.0
PYH1_k127_7691048_4 COG2801 Transposase and inactivated derivatives - - - 0.0000002371 57.0
PYH1_k127_7695506_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 459.0
PYH1_k127_7695506_1 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000001446 181.0
PYH1_k127_7695506_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000009935 170.0
PYH1_k127_7695506_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000001009 150.0
PYH1_k127_7701810_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1194.0
PYH1_k127_7701810_1 Elongation factor G, domain IV K02355 - - 2.286e-307 955.0
PYH1_k127_7701810_10 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 327.0
PYH1_k127_7701810_11 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 306.0
PYH1_k127_7701810_12 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001321 259.0
PYH1_k127_7701810_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
PYH1_k127_7701810_14 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000006812 165.0
PYH1_k127_7701810_15 Putative transposase - - - 0.0000000000000000000000001805 123.0
PYH1_k127_7701810_2 Aldehyde dehydrogenase family - - - 2.626e-212 667.0
PYH1_k127_7701810_3 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 597.0
PYH1_k127_7701810_4 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 589.0
PYH1_k127_7701810_5 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 558.0
PYH1_k127_7701810_6 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 467.0
PYH1_k127_7701810_7 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 449.0
PYH1_k127_7701810_8 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 387.0
PYH1_k127_7701810_9 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
PYH1_k127_7709726_0 Predicted Permease Membrane Region - - - 8.775e-202 643.0
PYH1_k127_7709726_1 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 573.0
PYH1_k127_7709726_2 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000004798 141.0
PYH1_k127_7709726_3 PFAM Bacterial protein of - - - 0.000000000000000000000005981 108.0
PYH1_k127_7716163_0 oxidoreductase activity - - - 8.45e-301 931.0
PYH1_k127_7716163_1 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 554.0
PYH1_k127_7723193_0 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 345.0
PYH1_k127_7723193_1 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000004339 212.0
PYH1_k127_7723193_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000006215 103.0
PYH1_k127_7723193_3 lipolytic protein G-D-S-L family - - - 0.00000000000000001082 96.0
PYH1_k127_7723193_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000005797 60.0
PYH1_k127_7749965_0 COG0277 FAD FMN-containing dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 541.0
PYH1_k127_7749965_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 426.0
PYH1_k127_7749965_2 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 302.0
PYH1_k127_7749965_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
PYH1_k127_7749965_4 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000004675 124.0
PYH1_k127_7749965_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000009624 109.0
PYH1_k127_7749965_6 Domain of unknown function (DUF4124) - - - 0.0002306 49.0
PYH1_k127_7758769_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.356e-253 786.0
PYH1_k127_7758769_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 388.0
PYH1_k127_7758769_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 366.0
PYH1_k127_7758769_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 327.0
PYH1_k127_7758769_4 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
PYH1_k127_7758769_5 mRNA binding - - - 0.000000000000000000000000005808 115.0
PYH1_k127_7758769_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000009349 110.0
PYH1_k127_7758769_7 diguanylate cyclase - - - 0.000000000000000000000001183 118.0
PYH1_k127_7765335_0 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 2.687e-209 662.0
PYH1_k127_7765335_1 positive regulation of growth - - - 0.00000003136 59.0
PYH1_k127_7775186_0 peptidase M24 K01262 - 3.4.11.9 3.95e-258 809.0
PYH1_k127_7775186_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
PYH1_k127_7775186_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
PYH1_k127_7775186_11 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
PYH1_k127_7775186_12 Histidine kinase K07648 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000007761 259.0
PYH1_k127_7775186_13 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
PYH1_k127_7775186_14 Beta-lactamase - - - 0.00000000000000000000000000000000000005493 148.0
PYH1_k127_7775186_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001698 136.0
PYH1_k127_7775186_16 Cold shock K03704 - - 0.000000000000000000000000009522 109.0
PYH1_k127_7775186_17 RsgA GTPase K06949 - 3.1.3.100 0.000001536 51.0
PYH1_k127_7775186_18 - - - - 0.00002471 48.0
PYH1_k127_7775186_2 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 412.0
PYH1_k127_7775186_3 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 395.0
PYH1_k127_7775186_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 396.0
PYH1_k127_7775186_5 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
PYH1_k127_7775186_6 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
PYH1_k127_7775186_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 374.0
PYH1_k127_7775186_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 317.0
PYH1_k127_7775186_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
PYH1_k127_7791125_0 oxidoreductase K04090 - 1.2.7.8 0.0 1645.0
PYH1_k127_7791125_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 582.0
PYH1_k127_7791125_10 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.000003785 59.0
PYH1_k127_7791125_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 502.0
PYH1_k127_7791125_3 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
PYH1_k127_7791125_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004669 231.0
PYH1_k127_7791125_5 membrane - - - 0.0000000000000000000000000000000000000000000000000004358 188.0
PYH1_k127_7791125_6 Glycine cleavage H-protein - - - 0.0000000000000000000000001716 112.0
PYH1_k127_7791125_7 DsrE/DsrF-like family - - - 0.000000000000000121 84.0
PYH1_k127_7791125_8 aminotransferase class I and II - - - 0.0000000000009871 68.0
PYH1_k127_7791125_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000003532 55.0
PYH1_k127_7791220_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.698e-246 773.0
PYH1_k127_7791220_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 4.054e-218 693.0
PYH1_k127_7791220_10 FCD - - - 0.0000000000000000000000000000000000000000000000000003471 189.0
PYH1_k127_7791220_11 tellurite resistance protein - - - 0.00000000000000000000000000000000000000000000000596 181.0
PYH1_k127_7791220_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 408.0
PYH1_k127_7791220_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 349.0
PYH1_k127_7791220_4 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
PYH1_k127_7791220_5 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 335.0
PYH1_k127_7791220_6 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 311.0
PYH1_k127_7791220_7 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 300.0
PYH1_k127_7791220_8 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
PYH1_k127_7791220_9 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001228 274.0
PYH1_k127_7809160_0 Prolyl oligopeptidase K01322 - 3.4.21.26 4.941e-234 743.0
PYH1_k127_7809160_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 419.0
PYH1_k127_7809160_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001137 226.0
PYH1_k127_7809160_3 - - - - 0.000000000000000000000000000000004129 135.0
PYH1_k127_7809160_4 HI0933-like protein K07007 - - 0.000000000000000008985 83.0
PYH1_k127_7840388_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.197e-265 836.0
PYH1_k127_7840388_1 DNA polymerase K00986 - 2.7.7.49 4.641e-223 701.0
PYH1_k127_7840388_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
PYH1_k127_7840388_11 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000001722 211.0
PYH1_k127_7840388_12 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000001562 208.0
PYH1_k127_7840388_13 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000002451 216.0
PYH1_k127_7840388_14 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
PYH1_k127_7840388_15 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000001383 193.0
PYH1_k127_7840388_16 PAC sensor-containing diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000402 190.0
PYH1_k127_7840388_17 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000009304 169.0
PYH1_k127_7840388_18 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000003388 128.0
PYH1_k127_7840388_19 - - - - 0.000000000000000000000000000002125 128.0
PYH1_k127_7840388_2 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.342e-203 641.0
PYH1_k127_7840388_20 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000001305 123.0
PYH1_k127_7840388_21 Belongs to the pirin family K06911 - - 0.000000000000000001259 85.0
PYH1_k127_7840388_3 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 535.0
PYH1_k127_7840388_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 532.0
PYH1_k127_7840388_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 490.0
PYH1_k127_7840388_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 465.0
PYH1_k127_7840388_7 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 394.0
PYH1_k127_7840388_8 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 372.0
PYH1_k127_7840388_9 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
PYH1_k127_7868702_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 7.494e-222 700.0
PYH1_k127_7868702_1 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 314.0
PYH1_k127_7868702_2 COG1335 Amidases related to nicotinamidase - - - 0.00000000000005034 81.0
PYH1_k127_7882194_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.807e-239 758.0
PYH1_k127_7882194_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 599.0
PYH1_k127_7882194_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000768 151.0
PYH1_k127_7882194_11 - - - - 0.00000000000000000000007676 104.0
PYH1_k127_7882194_12 Dienelactone hydrolase family - - - 0.0000000000002988 75.0
PYH1_k127_7882194_13 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0008015 48.0
PYH1_k127_7882194_2 Pfam:DUF989 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 582.0
PYH1_k127_7882194_3 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 470.0
PYH1_k127_7882194_4 signal transduction protein containing sensor and EAL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 319.0
PYH1_k127_7882194_5 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 318.0
PYH1_k127_7882194_6 Carboxylesterase family K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
PYH1_k127_7882194_7 Basic membrane lipoprotein K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000002143 226.0
PYH1_k127_7882194_8 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000005917 174.0
PYH1_k127_7882194_9 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000007471 153.0
PYH1_k127_7903677_0 Domain of unknown function (DUF3362) - - - 0.0 1234.0
PYH1_k127_7903677_1 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 584.0
PYH1_k127_7903677_10 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 293.0
PYH1_k127_7903677_11 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
PYH1_k127_7903677_12 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002112 288.0
PYH1_k127_7903677_13 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004041 290.0
PYH1_k127_7903677_14 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
PYH1_k127_7903677_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.0000000000000000000000000000000000000000000000000000000000000000000026 240.0
PYH1_k127_7903677_16 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000005745 231.0
PYH1_k127_7903677_17 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000001621 218.0
PYH1_k127_7903677_18 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000000000000000000000005197 214.0
PYH1_k127_7903677_19 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
PYH1_k127_7903677_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
PYH1_k127_7903677_20 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000002504 210.0
PYH1_k127_7903677_21 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000007369 198.0
PYH1_k127_7903677_22 TPM domain - - - 0.00000000000000000000000000000000000000000000000002829 185.0
PYH1_k127_7903677_23 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000001231 177.0
PYH1_k127_7903677_24 - - - - 0.00000000000000000000000000000000000005788 146.0
PYH1_k127_7903677_25 SnoaL-like domain - - - 0.0000000000000000000000000000000001125 137.0
PYH1_k127_7903677_26 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000332 130.0
PYH1_k127_7903677_27 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001383 102.0
PYH1_k127_7903677_28 Hemerythrin HHE cation binding domain - - - 0.00000000000000001125 89.0
PYH1_k127_7903677_29 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000004384 54.0
PYH1_k127_7903677_3 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 419.0
PYH1_k127_7903677_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 402.0
PYH1_k127_7903677_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
PYH1_k127_7903677_6 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
PYH1_k127_7903677_7 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 330.0
PYH1_k127_7903677_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
PYH1_k127_7903677_9 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 291.0
PYH1_k127_7925175_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 465.0
PYH1_k127_7925175_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000775 125.0
PYH1_k127_7925175_2 - - - - 0.000695 46.0
PYH1_k127_8000490_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 2.546e-269 850.0
PYH1_k127_8000490_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 8.797e-204 646.0
PYH1_k127_8000490_10 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 344.0
PYH1_k127_8000490_11 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 336.0
PYH1_k127_8000490_12 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
PYH1_k127_8000490_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000001776 215.0
PYH1_k127_8000490_14 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000003744 189.0
PYH1_k127_8000490_15 system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000005919 153.0
PYH1_k127_8000490_16 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000008521 155.0
PYH1_k127_8000490_17 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000002408 143.0
PYH1_k127_8000490_18 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000005962 134.0
PYH1_k127_8000490_19 PFAM Tol-Pal system TolA K03646 - - 0.00000000000000000000000008166 123.0
PYH1_k127_8000490_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 515.0
PYH1_k127_8000490_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 487.0
PYH1_k127_8000490_4 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 468.0
PYH1_k127_8000490_5 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 449.0
PYH1_k127_8000490_6 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 442.0
PYH1_k127_8000490_7 dioxygenase activity K00477 - 1.14.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 398.0
PYH1_k127_8000490_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 394.0
PYH1_k127_8000490_9 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 372.0
PYH1_k127_8046085_0 Histidine kinase K02487,K06596 - - 1.731e-307 990.0
PYH1_k127_8046085_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 606.0
PYH1_k127_8046085_10 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 340.0
PYH1_k127_8046085_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 336.0
PYH1_k127_8046085_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 317.0
PYH1_k127_8046085_13 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 304.0
PYH1_k127_8046085_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
PYH1_k127_8046085_15 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001735 254.0
PYH1_k127_8046085_16 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000008424 231.0
PYH1_k127_8046085_17 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
PYH1_k127_8046085_18 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
PYH1_k127_8046085_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
PYH1_k127_8046085_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 562.0
PYH1_k127_8046085_20 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000001152 214.0
PYH1_k127_8046085_21 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000003451 209.0
PYH1_k127_8046085_22 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000006765 202.0
PYH1_k127_8046085_23 Phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000001912 195.0
PYH1_k127_8046085_24 - - - - 0.00000000000000000000000000000000000000000000000000139 195.0
PYH1_k127_8046085_25 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000002496 184.0
PYH1_k127_8046085_26 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000003627 177.0
PYH1_k127_8046085_27 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000004619 164.0
PYH1_k127_8046085_28 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000225 139.0
PYH1_k127_8046085_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001054 121.0
PYH1_k127_8046085_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 519.0
PYH1_k127_8046085_30 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000001346 111.0
PYH1_k127_8046085_31 CAAX amino terminal protease family K07052 - - 0.000000000000000000001775 104.0
PYH1_k127_8046085_32 Prokaryotic cytochrome b561 K12262 - - 0.0002336 46.0
PYH1_k127_8046085_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 481.0
PYH1_k127_8046085_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
PYH1_k127_8046085_6 NADH:flavin oxidoreductase / NADH oxidase family K00354,K09461 - 1.14.13.40,1.6.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 466.0
PYH1_k127_8046085_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 402.0
PYH1_k127_8046085_8 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
PYH1_k127_8046085_9 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 367.0
PYH1_k127_8101525_0 Transposase DDE domain - - - 7.789e-254 795.0
PYH1_k127_8101525_1 ABC-type dipeptide transport system periplasmic component K02035 - - 4.347e-219 694.0
PYH1_k127_8101525_10 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000006697 243.0
PYH1_k127_8101525_11 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.000000000000003885 76.0
PYH1_k127_8101525_12 Belongs to the ParB family K03497 - - 0.0000000000000135 79.0
PYH1_k127_8101525_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 588.0
PYH1_k127_8101525_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 503.0
PYH1_k127_8101525_4 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 502.0
PYH1_k127_8101525_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 492.0
PYH1_k127_8101525_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 416.0
PYH1_k127_8101525_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 417.0
PYH1_k127_8101525_8 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 411.0
PYH1_k127_8101525_9 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
PYH1_k127_8152577_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 3.378e-313 979.0
PYH1_k127_8152577_1 NHL repeat - - - 4.964e-217 678.0
PYH1_k127_8152577_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 341.0
PYH1_k127_8152577_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
PYH1_k127_8152577_12 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
PYH1_k127_8152577_13 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000001091 242.0
PYH1_k127_8152577_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
PYH1_k127_8152577_15 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000000000000000000003783 215.0
PYH1_k127_8152577_16 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000004014 193.0
PYH1_k127_8152577_17 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001961 166.0
PYH1_k127_8152577_18 transcriptional regulator - - - 0.0000000000000000000000000000000000005675 144.0
PYH1_k127_8152577_19 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000469 133.0
PYH1_k127_8152577_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 594.0
PYH1_k127_8152577_20 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000002261 108.0
PYH1_k127_8152577_21 ferredoxin - - - 0.00000000000009751 73.0
PYH1_k127_8152577_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 570.0
PYH1_k127_8152577_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 545.0
PYH1_k127_8152577_5 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 534.0
PYH1_k127_8152577_6 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 383.0
PYH1_k127_8152577_7 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 368.0
PYH1_k127_8152577_8 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 353.0
PYH1_k127_8152577_9 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
PYH1_k127_8171725_0 Maltose transport system permease protein MalF P2 domain K10109 - - 8.556e-242 759.0
PYH1_k127_8171725_1 Bacterial extracellular solute-binding protein K10108 - - 1.327e-220 689.0
PYH1_k127_8171725_2 Binding-protein-dependent transport system inner membrane component K10110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 527.0
PYH1_k127_8171725_3 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 311.0
PYH1_k127_8171725_4 ABC transporter K10111 - - 0.0000000000000000000000000000000000000000000000000003061 187.0
PYH1_k127_8192072_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 419.0
PYH1_k127_8192072_1 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 382.0
PYH1_k127_8192072_2 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000003204 91.0
PYH1_k127_8232850_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 1.972e-277 862.0
PYH1_k127_8232850_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.518e-213 671.0
PYH1_k127_8232850_2 Dehydrogenase K15515 - 1.2.1.81 1.664e-208 657.0
PYH1_k127_8232850_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 494.0
PYH1_k127_8232850_4 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 463.0
PYH1_k127_8232850_5 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000002169 185.0
PYH1_k127_8232850_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000002643 154.0
PYH1_k127_847309_0 General function prediction only K06020 - 3.6.3.25 3.597e-289 898.0
PYH1_k127_847309_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 591.0
PYH1_k127_847309_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
PYH1_k127_847309_3 Patatin phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 412.0
PYH1_k127_847309_4 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 396.0
PYH1_k127_847309_5 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000002665 194.0
PYH1_k127_847309_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000002103 199.0
PYH1_k127_847309_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000003609 112.0
PYH1_k127_847309_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000839 48.0
PYH1_k127_850179_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 547.0
PYH1_k127_850179_1 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 340.0
PYH1_k127_858262_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1328.0
PYH1_k127_858262_1 D-amino acid K00285 - 1.4.5.1 1.734e-210 659.0
PYH1_k127_858262_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
PYH1_k127_858262_11 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 387.0
PYH1_k127_858262_12 binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 359.0
PYH1_k127_858262_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 335.0
PYH1_k127_858262_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000009055 261.0
PYH1_k127_858262_16 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
PYH1_k127_858262_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
PYH1_k127_858262_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 572.0
PYH1_k127_858262_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 572.0
PYH1_k127_858262_4 PFAM extracellular solute-binding protein family 1 K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
PYH1_k127_858262_5 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 481.0
PYH1_k127_858262_6 Serine hydroxymethyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 473.0
PYH1_k127_858262_7 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 450.0
PYH1_k127_858262_8 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 431.0
PYH1_k127_858262_9 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
PYH1_k127_858492_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.308e-289 903.0
PYH1_k127_858492_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.639e-238 742.0
PYH1_k127_858492_10 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000872 130.0
PYH1_k127_858492_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 403.0
PYH1_k127_858492_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 406.0
PYH1_k127_858492_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 396.0
PYH1_k127_858492_5 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 373.0
PYH1_k127_858492_6 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 305.0
PYH1_k127_858492_7 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 284.0
PYH1_k127_858492_8 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
PYH1_k127_858492_9 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000002798 185.0
PYH1_k127_874348_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1183.0
PYH1_k127_874348_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 5.016e-231 724.0
PYH1_k127_874348_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 398.0
PYH1_k127_874348_11 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 408.0
PYH1_k127_874348_12 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 398.0
PYH1_k127_874348_13 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 392.0
PYH1_k127_874348_14 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 396.0
PYH1_k127_874348_15 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 362.0
PYH1_k127_874348_16 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 344.0
PYH1_k127_874348_17 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 344.0
PYH1_k127_874348_18 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 311.0
PYH1_k127_874348_19 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 293.0
PYH1_k127_874348_2 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.241e-223 700.0
PYH1_k127_874348_20 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
PYH1_k127_874348_21 YaeQ family - - - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
PYH1_k127_874348_22 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
PYH1_k127_874348_23 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000009009 194.0
PYH1_k127_874348_24 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001312 194.0
PYH1_k127_874348_25 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000003604 150.0
PYH1_k127_874348_26 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000002825 129.0
PYH1_k127_874348_27 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000262 124.0
PYH1_k127_874348_28 PFAM FMN-binding domain - - - 0.00000000000000000000000000161 124.0
PYH1_k127_874348_29 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000005051 90.0
PYH1_k127_874348_3 Periplasmic binding protein K01999 - - 5.347e-203 648.0
PYH1_k127_874348_30 NADH pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.000000008318 59.0
PYH1_k127_874348_31 nadh pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 0.00000006877 57.0
PYH1_k127_874348_4 PFAM Prokaryotic protein of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 542.0
PYH1_k127_874348_5 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 488.0
PYH1_k127_874348_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 447.0
PYH1_k127_874348_8 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 429.0
PYH1_k127_874348_9 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 428.0
PYH1_k127_878938_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 377.0
PYH1_k127_878938_1 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002357 282.0
PYH1_k127_897663_0 Protein of unknown function (DUF3141) - - - 0.0 1068.0
PYH1_k127_897663_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 557.0
PYH1_k127_897663_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
PYH1_k127_897663_11 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000003161 181.0
PYH1_k127_897663_12 long-chain fatty acid transport protein - - - 0.000000000002971 72.0
PYH1_k127_897663_13 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000314 48.0
PYH1_k127_897663_14 AI-2E family transporter - - - 0.0007058 43.0
PYH1_k127_897663_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 551.0
PYH1_k127_897663_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 537.0
PYH1_k127_897663_4 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 507.0
PYH1_k127_897663_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 440.0
PYH1_k127_897663_6 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 388.0
PYH1_k127_897663_7 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 351.0
PYH1_k127_897663_8 Coenzyme A transferase K01035 - 2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 346.0
PYH1_k127_897663_9 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 336.0
PYH1_k127_910779_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 1.922e-207 664.0
PYH1_k127_910779_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 549.0
PYH1_k127_910779_10 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
PYH1_k127_910779_11 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000001542 191.0
PYH1_k127_910779_12 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000944 167.0
PYH1_k127_910779_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002927 166.0
PYH1_k127_910779_14 - - - - 0.00000000000000000000000000000000000000001691 164.0
PYH1_k127_910779_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000001278 155.0
PYH1_k127_910779_16 acetyltransferase - - - 0.000000000000000000000000000000000001748 144.0
PYH1_k127_910779_17 Rubrerythrin - - - 0.00000000000000000000000000000000001169 148.0
PYH1_k127_910779_18 PFAM glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000002584 119.0
PYH1_k127_910779_19 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000108 91.0
PYH1_k127_910779_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 534.0
PYH1_k127_910779_20 DUF167 K09131 - - 0.000000000000000001188 88.0
PYH1_k127_910779_21 Phosphotransferase System K11189 - - 0.0000000000000003634 82.0
PYH1_k127_910779_22 SnoaL-like domain - - - 0.000000008645 61.0
PYH1_k127_910779_23 - - - - 0.0003345 45.0
PYH1_k127_910779_24 Protein of unknown function (DUF2934) - - - 0.0003671 48.0
PYH1_k127_910779_25 MacB-like periplasmic core domain K02004 - - 0.0007191 49.0
PYH1_k127_910779_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 537.0
PYH1_k127_910779_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 446.0
PYH1_k127_910779_5 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
PYH1_k127_910779_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 362.0
PYH1_k127_910779_7 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
PYH1_k127_910779_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002432 269.0
PYH1_k127_910779_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004983 259.0
PYH1_k127_965076_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1482.0
PYH1_k127_965076_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 3.386e-317 978.0
PYH1_k127_965076_10 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000003095 154.0
PYH1_k127_965076_11 Psort location Extracellular, score - - - 0.0000000000000000000000000221 118.0
PYH1_k127_965076_12 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000003205 108.0
PYH1_k127_965076_13 Cysteine-rich secretory protein family - - - 0.00000000000000000000008583 106.0
PYH1_k127_965076_14 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000006057 104.0
PYH1_k127_965076_15 MlaD protein K02067 - - 0.0000000000007996 79.0
PYH1_k127_965076_16 - - - - 0.0005382 51.0
PYH1_k127_965076_2 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.071e-245 765.0
PYH1_k127_965076_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.443e-213 668.0
PYH1_k127_965076_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 567.0
PYH1_k127_965076_5 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 446.0
PYH1_k127_965076_6 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
PYH1_k127_965076_7 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
PYH1_k127_965076_8 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002357 280.0
PYH1_k127_965076_9 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.00000000000000000000000000000000000000001001 156.0
PYH1_k127_992900_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.782e-238 750.0
PYH1_k127_992900_1 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 326.0
PYH1_k127_992900_2 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 289.0
PYH1_k127_992900_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000006771 211.0
PYH1_k127_992900_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000003566 179.0
PYH1_k127_992900_5 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.000000000000000000000000000000000000000000004776 175.0
PYH1_k127_992900_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000009823 110.0