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Overview

ID MAG03160
Name PYH1_bin.57
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family Fen-1064
Genus JAURWL01
Species
Assembly information
Completeness (%) 92.69
Contamination (%) 4.48
GC content (%) 52.0
N50 (bp) 10,889
Genome size (bp) 2,259,942

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2195

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1010019_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.269e-245 768.0
PYH1_k127_1010019_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.137e-215 680.0
PYH1_k127_1010019_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 460.0
PYH1_k127_1010019_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 307.0
PYH1_k127_1010019_4 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 308.0
PYH1_k127_1010019_5 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000004324 179.0
PYH1_k127_1010019_6 - - - - 0.0000000000000006298 81.0
PYH1_k127_1010019_7 YmdB-like protein K09769 - - 0.000000000000000739 78.0
PYH1_k127_102977_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 348.0
PYH1_k127_102977_1 protein-glutamate methylesterase K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 314.0
PYH1_k127_102977_10 PFAM Integrase catalytic region K07497 - - 0.0000006143 52.0
PYH1_k127_102977_11 transposase activity K07483,K07497 - - 0.00005272 48.0
PYH1_k127_102977_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000005007 208.0
PYH1_k127_102977_3 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000009971 165.0
PYH1_k127_102977_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000001977 149.0
PYH1_k127_102977_5 Secreted repeat of unknown function - - - 0.000000000000000000000000000003379 131.0
PYH1_k127_102977_6 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000196 110.0
PYH1_k127_102977_7 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000003534 103.0
PYH1_k127_102977_8 TfoX N-terminal domain - - - 0.0000000000000000000007317 98.0
PYH1_k127_102977_9 hmm pf02371 K07486 - - 0.0000000004695 60.0
PYH1_k127_1039495_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 4.024e-281 882.0
PYH1_k127_1039495_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000001804 115.0
PYH1_k127_105425_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5e-324 1002.0
PYH1_k127_105425_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.667e-242 762.0
PYH1_k127_105425_10 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000001561 65.0
PYH1_k127_105425_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 500.0
PYH1_k127_105425_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 456.0
PYH1_k127_105425_4 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
PYH1_k127_105425_5 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001294 241.0
PYH1_k127_105425_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000529 237.0
PYH1_k127_105425_7 lipoprotein transporter activity K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000002913 224.0
PYH1_k127_105425_8 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000001277 175.0
PYH1_k127_1081812_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 317.0
PYH1_k127_1081812_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
PYH1_k127_1081812_10 ABC-2 family transporter protein - - - 0.000000000000000000000002654 112.0
PYH1_k127_1081812_11 PFAM Electron transfer flavoprotein domain K03522,K22432 - 1.3.1.108 0.000000000000000004523 91.0
PYH1_k127_1081812_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 296.0
PYH1_k127_1081812_3 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008983 286.0
PYH1_k127_1081812_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005468 281.0
PYH1_k127_1081812_5 Epoxide hydrolase 2 K08726,K10089 GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006633,GO:0006690,GO:0006725,GO:0006793,GO:0006796,GO:0006805,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007031,GO:0007600,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008610,GO:0009056,GO:0009058,GO:0009410,GO:0009636,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015031,GO:0015643,GO:0015833,GO:0016043,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0017144,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019369,GO:0019373,GO:0019439,GO:0019725,GO:0019752,GO:0030003,GO:0030258,GO:0031907,GO:0031974,GO:0032501,GO:0032787,GO:0033036,GO:0033365,GO:0033559,GO:0034613,GO:0035150,GO:0035296,GO:0042221,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042759,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045777,GO:0046272,GO:0046394,GO:0046483,GO:0046839,GO:0046872,GO:0046907,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050801,GO:0050877,GO:0050880,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0071466,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072330,GO:0072503,GO:0072507,GO:0072593,GO:0072594,GO:0072662,GO:0072663,GO:0080090,GO:0090066,GO:0090181,GO:0097176,GO:0097746,GO:0097755,GO:0098771,GO:1900673,GO:1901360,GO:1901361,GO:1901568,GO:1901575,GO:1901576 3.1.3.76,3.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001105 272.0
PYH1_k127_1081812_6 dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
PYH1_k127_1081812_7 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000001863 223.0
PYH1_k127_1081812_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000381 197.0
PYH1_k127_1081812_9 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000002645 139.0
PYH1_k127_1105739_0 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 465.0
PYH1_k127_1105739_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
PYH1_k127_1105739_2 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 349.0
PYH1_k127_1105739_3 MFS_1 like family - - - 0.000000000000000000000000000000000468 151.0
PYH1_k127_1105739_4 NADPH-dependent FMN reductase - - - 0.0003116 44.0
PYH1_k127_1111481_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 372.0
PYH1_k127_1111481_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001065 261.0
PYH1_k127_1111481_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001043 127.0
PYH1_k127_1111481_3 Methylmuconolactone methyl-isomerase - - - 0.000000000000006708 79.0
PYH1_k127_1117553_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 577.0
PYH1_k127_1117553_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
PYH1_k127_1117553_2 - - - - 0.0000000000004666 72.0
PYH1_k127_1117553_3 Signal peptide protein - - - 0.000000000272 64.0
PYH1_k127_112395_0 Biotin carboxylase C-terminal domain - - - 0.0 1225.0
PYH1_k127_112395_1 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
PYH1_k127_112395_2 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 314.0
PYH1_k127_112395_3 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000002851 189.0
PYH1_k127_112395_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000009613 154.0
PYH1_k127_112395_5 Thioesterase superfamily - - - 0.000000000000001603 80.0
PYH1_k127_1135038_0 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 429.0
PYH1_k127_1135038_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 384.0
PYH1_k127_1135038_10 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000266 124.0
PYH1_k127_1135038_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000009565 69.0
PYH1_k127_1135038_2 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 361.0
PYH1_k127_1135038_3 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 351.0
PYH1_k127_1135038_4 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 267.0
PYH1_k127_1135038_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH1_k127_1135038_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
PYH1_k127_1135038_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000008346 204.0
PYH1_k127_1135038_8 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000007082 177.0
PYH1_k127_1135038_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000755 170.0
PYH1_k127_1135186_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 580.0
PYH1_k127_1135186_1 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 465.0
PYH1_k127_1135186_11 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000001212 191.0
PYH1_k127_1135186_12 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000000002516 173.0
PYH1_k127_1135186_13 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000003696 167.0
PYH1_k127_1135186_14 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000007967 162.0
PYH1_k127_1135186_15 Predicted membrane protein (DUF2177) - - - 0.00000000000000000000000000000000005734 138.0
PYH1_k127_1135186_16 Universal stress protein family - - - 0.00000000000000000000000000003258 128.0
PYH1_k127_1135186_17 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000001052 101.0
PYH1_k127_1135186_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000003467 88.0
PYH1_k127_1135186_19 Beta-lactamase - - - 0.000000000000002707 79.0
PYH1_k127_1135186_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 393.0
PYH1_k127_1135186_20 Protein of unknown function (DUF3243) - - - 0.0000000000008957 71.0
PYH1_k127_1135186_21 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000002568 61.0
PYH1_k127_1135186_22 Rubrerythrin - - - 0.000001799 55.0
PYH1_k127_1135186_23 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000009839 48.0
PYH1_k127_1135186_3 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 392.0
PYH1_k127_1135186_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 356.0
PYH1_k127_1135186_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 340.0
PYH1_k127_1135186_6 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 306.0
PYH1_k127_1135186_7 acetylesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006141 289.0
PYH1_k127_1135186_8 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000002386 229.0
PYH1_k127_1135186_9 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000007731 203.0
PYH1_k127_1137341_0 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 466.0
PYH1_k127_1137341_1 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
PYH1_k127_1137341_3 PFAM Integrase catalytic region K07497 - - 0.000006976 50.0
PYH1_k127_1137341_4 Protein of unknown function (DUF998) - - - 0.00002085 55.0
PYH1_k127_115413_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 5.569e-221 693.0
PYH1_k127_115413_1 Arsenical pump membrane protein K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 593.0
PYH1_k127_115413_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 543.0
PYH1_k127_115413_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 415.0
PYH1_k127_115413_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000002271 234.0
PYH1_k127_115413_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001236 183.0
PYH1_k127_115413_6 AMP binding - - - 0.0000000000000000000000000000000000000000000000003719 187.0
PYH1_k127_115413_7 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000004051 158.0
PYH1_k127_115413_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.00000000000000000000000000000000000000001576 159.0
PYH1_k127_1174074_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 8.196e-232 734.0
PYH1_k127_1174074_1 4Fe-4S dicluster domain K00124 - - 0.000000000001151 68.0
PYH1_k127_117870_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 580.0
PYH1_k127_117870_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 479.0
PYH1_k127_117870_10 Amino acid permease - - - 0.00000000000001863 74.0
PYH1_k127_117870_2 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006272 251.0
PYH1_k127_117870_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
PYH1_k127_117870_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000006466 242.0
PYH1_k127_117870_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000791 249.0
PYH1_k127_117870_6 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001736 226.0
PYH1_k127_117870_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000007101 201.0
PYH1_k127_117870_8 PFAM Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000003666 114.0
PYH1_k127_117870_9 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000001799 103.0
PYH1_k127_1191484_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 7.964e-300 929.0
PYH1_k127_1191484_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.805e-233 729.0
PYH1_k127_1217286_0 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 7.948e-243 760.0
PYH1_k127_1217286_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 604.0
PYH1_k127_1217286_10 LamG domain protein jellyroll fold domain protein - - - 0.0000000000347 71.0
PYH1_k127_1217286_11 COG NOG16874 non supervised orthologous group - - - 0.0001486 49.0
PYH1_k127_1217286_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 512.0
PYH1_k127_1217286_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 355.0
PYH1_k127_1217286_4 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 306.0
PYH1_k127_1217286_5 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004875 248.0
PYH1_k127_1217286_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000005196 172.0
PYH1_k127_1217286_7 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000007314 171.0
PYH1_k127_1217286_8 ABC transporter, transmembrane K06147 - - 0.00000000000000000000000000001143 120.0
PYH1_k127_1217286_9 tetratricopeptide repeat - - - 0.000000000000000000000004053 112.0
PYH1_k127_1222509_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 376.0
PYH1_k127_1222509_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 330.0
PYH1_k127_1222509_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000002003 258.0
PYH1_k127_1222509_3 Helix-turn-helix domain K07497 - - 0.00000000000000000000000173 104.0
PYH1_k127_1222509_5 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282,K13419 - 2.7.11.1 0.0000000000593 68.0
PYH1_k127_1248672_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 427.0
PYH1_k127_1248672_1 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001069 250.0
PYH1_k127_1248672_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000023 196.0
PYH1_k127_1248672_3 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000001703 135.0
PYH1_k127_1248672_4 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000003788 125.0
PYH1_k127_1248672_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000008591 62.0
PYH1_k127_1248672_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.0001674 47.0
PYH1_k127_1248672_7 Elongation factor SelB, winged helix K03833 - - 0.0006531 44.0
PYH1_k127_128079_0 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0 1307.0
PYH1_k127_128079_1 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 362.0
PYH1_k127_128079_10 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000006349 146.0
PYH1_k127_128079_11 - - - - 0.0000000000000000000000000000000002139 144.0
PYH1_k127_128079_12 Peptidase family M54 K06974 - - 0.0000000000000000000000000000001893 132.0
PYH1_k127_128079_13 - - - - 0.0000000000000000000000000004081 122.0
PYH1_k127_128079_2 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 349.0
PYH1_k127_128079_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 321.0
PYH1_k127_128079_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 274.0
PYH1_k127_128079_5 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002494 233.0
PYH1_k127_128079_6 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000004136 209.0
PYH1_k127_128079_7 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000001699 170.0
PYH1_k127_128079_9 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000006082 149.0
PYH1_k127_1288070_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001033 271.0
PYH1_k127_1288070_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002783 273.0
PYH1_k127_1288070_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
PYH1_k127_1288070_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001451 234.0
PYH1_k127_1314033_0 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002858 278.0
PYH1_k127_1314033_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000006887 237.0
PYH1_k127_1314033_2 - - - - 0.0001452 49.0
PYH1_k127_1427432_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.821e-253 806.0
PYH1_k127_1427432_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000006721 177.0
PYH1_k127_1433173_0 Heat shock 70 kDa protein K04043 - - 2.045e-313 970.0
PYH1_k127_1433173_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 581.0
PYH1_k127_1433173_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 415.0
PYH1_k127_1433173_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 323.0
PYH1_k127_1433173_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH1_k127_1433173_5 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000003683 176.0
PYH1_k127_1433173_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000298 152.0
PYH1_k127_1433173_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000007927 162.0
PYH1_k127_1454592_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 8.832e-294 921.0
PYH1_k127_1454592_1 hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 572.0
PYH1_k127_1454592_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 378.0
PYH1_k127_1454592_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000009177 196.0
PYH1_k127_1454592_4 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.0000000000000000000000000000109 123.0
PYH1_k127_1490120_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
PYH1_k127_1490120_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000005363 215.0
PYH1_k127_1490120_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000003597 184.0
PYH1_k127_1490120_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000006606 107.0
PYH1_k127_1490120_4 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000000000809 86.0
PYH1_k127_1490120_5 Protein of unknown function (DUF998) - - - 0.00005438 54.0
PYH1_k127_150272_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 6.241e-195 616.0
PYH1_k127_150272_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 531.0
PYH1_k127_150272_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.0000000000000000000000000000000000000000000000000113 197.0
PYH1_k127_150272_4 - - - - 0.0000000000000005399 82.0
PYH1_k127_150272_5 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000005694 61.0
PYH1_k127_1554958_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 335.0
PYH1_k127_1554958_1 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000004171 205.0
PYH1_k127_1554958_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000001078 207.0
PYH1_k127_1554958_3 nUDIX hydrolase - - - 0.00000000000000000000000000000000000001139 150.0
PYH1_k127_1554958_4 (ABC) transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000001535 145.0
PYH1_k127_1554958_5 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000003451 128.0
PYH1_k127_1554958_6 Helix-turn-helix domain - - - 0.0000000000000000000000007696 112.0
PYH1_k127_1554958_7 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000002573 105.0
PYH1_k127_1554958_9 involved in chromosome partitioning - - - 0.000000002435 68.0
PYH1_k127_1583249_0 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 467.0
PYH1_k127_1623581_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000002159 123.0
PYH1_k127_1623581_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000009156 58.0
PYH1_k127_1635811_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 467.0
PYH1_k127_1635811_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 382.0
PYH1_k127_1635811_2 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 360.0
PYH1_k127_1635811_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
PYH1_k127_1635811_4 Arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000004118 193.0
PYH1_k127_1635811_5 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000002845 179.0
PYH1_k127_1635811_6 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000001843 79.0
PYH1_k127_1635811_7 Domain of unknown function (DUF4342) - - - 0.0000000001063 68.0
PYH1_k127_1684481_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.391e-203 644.0
PYH1_k127_1684481_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 438.0
PYH1_k127_1684481_10 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.00000000000000001238 84.0
PYH1_k127_1684481_11 Altronate hydrolase K01685 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7 0.0000000000009754 74.0
PYH1_k127_1684481_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 415.0
PYH1_k127_1684481_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 291.0
PYH1_k127_1684481_4 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000007098 213.0
PYH1_k127_1684481_5 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000000000000003945 147.0
PYH1_k127_1684481_6 - - - - 0.0000000000000000000000000000007873 126.0
PYH1_k127_1684481_7 Putative Fe-S cluster - - - 0.00000000000000000000000002867 114.0
PYH1_k127_1684481_8 Preprotein translocase subunit K03210 - - 0.0000000000000000001755 93.0
PYH1_k127_1684481_9 Putative zinc ribbon domain - - - 0.000000000000000009071 86.0
PYH1_k127_1701975_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 501.0
PYH1_k127_1701975_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 493.0
PYH1_k127_1701975_2 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000002877 187.0
PYH1_k127_1701975_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000019 156.0
PYH1_k127_1701975_4 Family of unknown function (DUF5343) - - - 0.000000000000000000000000000000000000004237 154.0
PYH1_k127_1701975_5 - - - - 0.0001621 46.0
PYH1_k127_171759_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 301.0
PYH1_k127_171759_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002414 282.0
PYH1_k127_171759_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000003341 241.0
PYH1_k127_171759_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000005203 174.0
PYH1_k127_1721569_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 521.0
PYH1_k127_1721569_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 400.0
PYH1_k127_1721569_2 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000002654 242.0
PYH1_k127_1721569_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000001419 234.0
PYH1_k127_1721569_4 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000007391 205.0
PYH1_k127_1721569_5 - - - - 0.00000005178 57.0
PYH1_k127_1730183_0 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 435.0
PYH1_k127_1730183_1 Radical SAM - - - 0.0000000000000000000000000000000000000000299 170.0
PYH1_k127_1730183_2 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000002025 93.0
PYH1_k127_1730183_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0008504 53.0
PYH1_k127_1733859_0 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 312.0
PYH1_k127_1733859_1 2-oxopent-4-enoate hydratase activity K02554 - 4.2.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001161 279.0
PYH1_k127_1735445_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.345e-276 867.0
PYH1_k127_1735445_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.39e-228 721.0
PYH1_k127_1735445_10 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
PYH1_k127_1735445_11 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 428.0
PYH1_k127_1735445_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 416.0
PYH1_k127_1735445_13 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 374.0
PYH1_k127_1735445_14 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
PYH1_k127_1735445_15 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 319.0
PYH1_k127_1735445_16 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 297.0
PYH1_k127_1735445_17 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
PYH1_k127_1735445_18 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
PYH1_k127_1735445_19 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 265.0
PYH1_k127_1735445_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 7.927e-218 687.0
PYH1_k127_1735445_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 245.0
PYH1_k127_1735445_21 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000005991 210.0
PYH1_k127_1735445_22 PFAM heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000006042 167.0
PYH1_k127_1735445_23 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000006044 165.0
PYH1_k127_1735445_24 - - - - 0.000000000000000000000000000000000000000008148 161.0
PYH1_k127_1735445_25 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000005865 110.0
PYH1_k127_1735445_26 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002181 109.0
PYH1_k127_1735445_27 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000000000001104 101.0
PYH1_k127_1735445_28 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000001928 91.0
PYH1_k127_1735445_29 - - - - 0.000000000000000002881 94.0
PYH1_k127_1735445_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.895e-203 636.0
PYH1_k127_1735445_30 Transcription factor zinc-finger K09981 - - 0.000000000007236 75.0
PYH1_k127_1735445_31 Enoyl-CoA hydratase - - - 0.0000000001188 66.0
PYH1_k127_1735445_32 - - - - 0.0000000002549 70.0
PYH1_k127_1735445_33 - - - - 0.00000002522 59.0
PYH1_k127_1735445_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 546.0
PYH1_k127_1735445_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 516.0
PYH1_k127_1735445_6 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 507.0
PYH1_k127_1735445_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 487.0
PYH1_k127_1735445_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 481.0
PYH1_k127_1735445_9 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 464.0
PYH1_k127_173735_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 4.971e-204 643.0
PYH1_k127_173735_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 393.0
PYH1_k127_173735_2 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
PYH1_k127_173735_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004511 265.0
PYH1_k127_173735_4 - - - - 0.00000000000000000000001572 108.0
PYH1_k127_173735_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000001094 68.0
PYH1_k127_1741095_0 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 567.0
PYH1_k127_1741095_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 458.0
PYH1_k127_1741095_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001042 198.0
PYH1_k127_1741095_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000001784 188.0
PYH1_k127_1741095_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000006817 182.0
PYH1_k127_1741095_13 Mo-molybdopterin cofactor metabolic process K02379,K03750,K03752,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.00000000000000000000000000000000000000000000001259 181.0
PYH1_k127_1741095_14 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000302 175.0
PYH1_k127_1741095_15 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000001959 166.0
PYH1_k127_1741095_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000339 164.0
PYH1_k127_1741095_17 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.00000000000000000000000000000000000000008063 163.0
PYH1_k127_1741095_18 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000005272 153.0
PYH1_k127_1741095_19 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000001044 133.0
PYH1_k127_1741095_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 434.0
PYH1_k127_1741095_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001059 136.0
PYH1_k127_1741095_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 372.0
PYH1_k127_1741095_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 352.0
PYH1_k127_1741095_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 327.0
PYH1_k127_1741095_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 316.0
PYH1_k127_1741095_7 3-oxoacid CoA-transferase, B subunit K01029 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
PYH1_k127_1741095_8 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01031 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000003427 241.0
PYH1_k127_1741095_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000003182 200.0
PYH1_k127_1754418_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 299.0
PYH1_k127_1754418_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000849 199.0
PYH1_k127_1754418_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000004649 83.0
PYH1_k127_1763005_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 464.0
PYH1_k127_1763005_1 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 270.0
PYH1_k127_1763005_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 224.0
PYH1_k127_1763005_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000004823 187.0
PYH1_k127_1766899_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 2.84e-200 629.0
PYH1_k127_1766899_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
PYH1_k127_1766899_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 350.0
PYH1_k127_1766899_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
PYH1_k127_1766899_4 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 290.0
PYH1_k127_1766899_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 237.0
PYH1_k127_1766899_6 NIL - - - 0.0000000000000000000000000000000000000000000000000000000018 202.0
PYH1_k127_1766899_7 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000005048 171.0
PYH1_k127_1766899_8 AAA domain - - - 0.000000000000000000003165 102.0
PYH1_k127_1766899_9 ThiS family K03636 - - 0.00000006275 57.0
PYH1_k127_1776473_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 444.0
PYH1_k127_1776473_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 357.0
PYH1_k127_1776473_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000009486 216.0
PYH1_k127_1776473_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004947 216.0
PYH1_k127_1776473_5 - - - - 0.000000000000000000000000000000000000000006187 163.0
PYH1_k127_1776473_6 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000001303 151.0
PYH1_k127_1776473_7 Thioredoxin-like - - - 0.000000000000000000000000001842 128.0
PYH1_k127_179031_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 457.0
PYH1_k127_179031_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008614 269.0
PYH1_k127_179031_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
PYH1_k127_179031_3 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000001095 126.0
PYH1_k127_1791943_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 567.0
PYH1_k127_1791943_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 466.0
PYH1_k127_1791943_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000001114 108.0
PYH1_k127_1791943_11 RDD family - - - 0.0000000000000000000001455 104.0
PYH1_k127_1791943_12 PspC domain - - - 0.00000000000000000002054 96.0
PYH1_k127_1791943_13 - - - - 0.00002748 51.0
PYH1_k127_1791943_2 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 413.0
PYH1_k127_1791943_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
PYH1_k127_1791943_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 304.0
PYH1_k127_1791943_5 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 293.0
PYH1_k127_1791943_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000004969 188.0
PYH1_k127_1791943_7 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000002162 181.0
PYH1_k127_1791943_8 Cupin domain - - - 0.000000000000000000000000000004316 123.0
PYH1_k127_1791943_9 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000001548 121.0
PYH1_k127_1860303_0 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 496.0
PYH1_k127_1860303_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 414.0
PYH1_k127_1860303_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
PYH1_k127_1860303_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000003904 123.0
PYH1_k127_1898049_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
PYH1_k127_1898049_1 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000007835 249.0
PYH1_k127_1898049_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000009327 202.0
PYH1_k127_1898049_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000008737 156.0
PYH1_k127_1898049_4 Acetyltransferase - - - 0.000000000000000000000000000000000000007634 149.0
PYH1_k127_1898049_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000003728 130.0
PYH1_k127_1898049_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000008962 70.0
PYH1_k127_1901116_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 552.0
PYH1_k127_1901116_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 464.0
PYH1_k127_1901116_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000003509 87.0
PYH1_k127_1901116_2 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 337.0
PYH1_k127_1901116_3 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
PYH1_k127_1901116_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002064 265.0
PYH1_k127_1901116_5 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
PYH1_k127_1901116_6 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 245.0
PYH1_k127_1901116_7 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000002934 137.0
PYH1_k127_1901116_8 3'-5' exonuclease activity K03547 - - 0.0000000000000000000000000000000542 134.0
PYH1_k127_1901116_9 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000009223 96.0
PYH1_k127_191385_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.84e-203 641.0
PYH1_k127_191385_1 Terminase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 580.0
PYH1_k127_191385_2 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 426.0
PYH1_k127_191385_3 - - - - 0.000000000000000000000000000000000001199 142.0
PYH1_k127_191385_4 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000000002787 130.0
PYH1_k127_191385_5 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000002687 114.0
PYH1_k127_1918853_0 Oxidoreductase K06151 - 1.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 457.0
PYH1_k127_1918853_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 384.0
PYH1_k127_1918853_10 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000002134 182.0
PYH1_k127_1918853_11 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000006042 167.0
PYH1_k127_1918853_12 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000003005 128.0
PYH1_k127_1918853_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000005285 85.0
PYH1_k127_1918853_14 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000000000000287 75.0
PYH1_k127_1918853_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
PYH1_k127_1918853_3 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 323.0
PYH1_k127_1918853_4 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002909 270.0
PYH1_k127_1918853_5 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002191 261.0
PYH1_k127_1918853_6 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002579 229.0
PYH1_k127_1918853_7 Alcohol dehydrogenase GroES-like domain K00008,K00094 - 1.1.1.14,1.1.1.251 0.00000000000000000000000000000000000000000000000000000000000262 222.0
PYH1_k127_1918853_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000001639 215.0
PYH1_k127_1918853_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000006852 201.0
PYH1_k127_198079_0 Drug exporters of the RND superfamily K06994,K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 535.0
PYH1_k127_198079_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 467.0
PYH1_k127_198079_10 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000000000004425 103.0
PYH1_k127_198079_11 - - - - 0.000000000000000001937 89.0
PYH1_k127_198079_12 Flavodoxin domain - - - 0.00000001867 63.0
PYH1_k127_198079_13 Protein of unknown function (DUF998) - - - 0.000267 51.0
PYH1_k127_198079_2 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
PYH1_k127_198079_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
PYH1_k127_198079_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000276 251.0
PYH1_k127_198079_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000001216 251.0
PYH1_k127_198079_6 basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000004911 227.0
PYH1_k127_198079_7 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000001448 222.0
PYH1_k127_198079_8 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000000000000000001662 133.0
PYH1_k127_198079_9 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000265 97.0
PYH1_k127_1987939_0 Recombinase zinc beta ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 491.0
PYH1_k127_1987939_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015,K18916 - 1.1.1.26,1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 379.0
PYH1_k127_1987939_10 Recombinase zinc beta ribbon domain - - - 0.00000000000000000000000769 104.0
PYH1_k127_1987939_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000008932 83.0
PYH1_k127_1987939_2 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 345.0
PYH1_k127_1987939_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 308.0
PYH1_k127_1987939_4 Phage integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002631 278.0
PYH1_k127_1987939_5 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 259.0
PYH1_k127_1987939_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000003568 196.0
PYH1_k127_1987939_7 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K00980 - 2.7.7.39 0.0000000000000000000000000000000000007085 145.0
PYH1_k127_1987939_8 Transposase - - - 0.00000000000000000000000000000000001504 136.0
PYH1_k127_1987939_9 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000013 132.0
PYH1_k127_2031082_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 493.0
PYH1_k127_2031082_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 449.0
PYH1_k127_2031082_10 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000001986 124.0
PYH1_k127_2031082_11 Protein of unknown function (DUF933) K06942 - - 0.000000000000000008435 87.0
PYH1_k127_2031082_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000007459 69.0
PYH1_k127_2031082_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 377.0
PYH1_k127_2031082_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
PYH1_k127_2031082_4 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 314.0
PYH1_k127_2031082_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 285.0
PYH1_k127_2031082_6 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000001109 243.0
PYH1_k127_2031082_7 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000002543 231.0
PYH1_k127_2031082_8 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH1_k127_2031082_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000007279 155.0
PYH1_k127_2048775_0 PFAM glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000000000001224 251.0
PYH1_k127_2048775_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000003363 237.0
PYH1_k127_2048775_10 - K01385 - 3.4.23.42 0.0001907 54.0
PYH1_k127_2048775_2 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000001118 190.0
PYH1_k127_2048775_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000604 177.0
PYH1_k127_2048775_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000004025 121.0
PYH1_k127_2048775_5 Protein of unknown function (DUF3343) - - - 0.0000000000000000000002989 101.0
PYH1_k127_2048775_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000002313 89.0
PYH1_k127_2048775_7 - K07112 - - 0.00000003182 65.0
PYH1_k127_2048775_8 PFAM Flavodoxin K03809 - 1.6.5.2 0.0000008717 57.0
PYH1_k127_2048775_9 Protein of unknown function (DUF3343) - - - 0.000002467 50.0
PYH1_k127_205092_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 539.0
PYH1_k127_205092_1 E3 Ubiquitin ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 427.0
PYH1_k127_205092_10 - - - - 0.00000000003128 64.0
PYH1_k127_205092_2 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 297.0
PYH1_k127_205092_3 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001259 282.0
PYH1_k127_205092_4 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001411 245.0
PYH1_k127_205092_5 - - - - 0.000000000000000000000000000000000000000000000000000000000004863 217.0
PYH1_k127_205092_6 PAC2 family - - - 0.0000000000000000000000000000000000000000000009267 175.0
PYH1_k127_205092_7 - - - - 0.000000000000000000000000000007768 128.0
PYH1_k127_205092_8 HicB family K18843 - - 0.0000000000000000123 87.0
PYH1_k127_2144202_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 306.0
PYH1_k127_2144202_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000009765 229.0
PYH1_k127_2144202_2 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000269 198.0
PYH1_k127_2160002_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.49e-226 714.0
PYH1_k127_2160002_1 Domain of unknown function (DUF4070) - - - 3.594e-201 638.0
PYH1_k127_2160002_10 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
PYH1_k127_2160002_11 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001678 264.0
PYH1_k127_2160002_12 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 270.0
PYH1_k127_2160002_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
PYH1_k127_2160002_14 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000716 222.0
PYH1_k127_2160002_15 PFAM Transglutaminase-like - - - 0.000000000000000000000000000000005771 135.0
PYH1_k127_2160002_16 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.00000000000000000000000000000002532 131.0
PYH1_k127_2160002_17 SNARE associated Golgi protein - - - 0.000000000000000000000000000001362 129.0
PYH1_k127_2160002_18 Protease prsW family - - - 0.0000000000000000000000000000081 130.0
PYH1_k127_2160002_19 - - - - 0.00000000000000000000000002253 109.0
PYH1_k127_2160002_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 542.0
PYH1_k127_2160002_20 - - - - 0.00000000000000002978 91.0
PYH1_k127_2160002_21 membrane protein domain - - - 0.0000000000000001395 85.0
PYH1_k127_2160002_22 - - - - 0.000000000000239 75.0
PYH1_k127_2160002_23 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000001416 77.0
PYH1_k127_2160002_24 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000006241 59.0
PYH1_k127_2160002_25 - - - - 0.0000166 49.0
PYH1_k127_2160002_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
PYH1_k127_2160002_4 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
PYH1_k127_2160002_5 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 363.0
PYH1_k127_2160002_6 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 350.0
PYH1_k127_2160002_7 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 343.0
PYH1_k127_2160002_8 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 333.0
PYH1_k127_2160002_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 324.0
PYH1_k127_2180935_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1313.0
PYH1_k127_2180935_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1215.0
PYH1_k127_2180935_10 KH domain K06346 - - 0.00000000000000000000000000000000000000000000000143 185.0
PYH1_k127_2180935_11 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000003038 177.0
PYH1_k127_2180935_12 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000002434 149.0
PYH1_k127_2180935_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000005864 116.0
PYH1_k127_2180935_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000005108 111.0
PYH1_k127_2180935_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000002863 96.0
PYH1_k127_2180935_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000008261 96.0
PYH1_k127_2180935_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001237 77.0
PYH1_k127_2180935_18 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001036 75.0
PYH1_k127_2180935_19 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000001495 49.0
PYH1_k127_2180935_2 R3H domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 544.0
PYH1_k127_2180935_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 527.0
PYH1_k127_2180935_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 340.0
PYH1_k127_2180935_5 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 294.0
PYH1_k127_2180935_6 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
PYH1_k127_2180935_7 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
PYH1_k127_2180935_8 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003909 252.0
PYH1_k127_2180935_9 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000001375 195.0
PYH1_k127_2188472_0 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000002868 259.0
PYH1_k127_2188472_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000005427 98.0
PYH1_k127_2188472_2 translation release factor activity - - - 0.00000000000001648 83.0
PYH1_k127_2231768_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001077 109.0
PYH1_k127_2231768_1 nUDIX hydrolase K01518,K08296 - 3.6.1.17 0.00000000000000000003632 94.0
PYH1_k127_2308463_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 520.0
PYH1_k127_2308463_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 445.0
PYH1_k127_2308463_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000005514 230.0
PYH1_k127_2308463_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000012 198.0
PYH1_k127_2308463_4 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000000000001433 112.0
PYH1_k127_2308463_5 nUDIX hydrolase K01518,K08296 - 3.6.1.17 0.000000000000000004994 91.0
PYH1_k127_2308463_6 - - - - 0.0000000000000005877 80.0
PYH1_k127_2308463_7 OsmC-like protein - - - 0.000006464 51.0
PYH1_k127_2340417_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 347.0
PYH1_k127_2340417_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 330.0
PYH1_k127_2340417_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000001199 244.0
PYH1_k127_2340417_3 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000005778 211.0
PYH1_k127_2340417_4 coenzyme A transferase K01031 - 2.8.3.6 0.000000000000000000000000000000000000001666 157.0
PYH1_k127_2340417_5 PFAM regulatory protein TetR - - - 0.000000000000000000000000000001068 129.0
PYH1_k127_2340417_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001733 117.0
PYH1_k127_2340417_7 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000009857 105.0
PYH1_k127_2340417_8 carnitine dehydratase K07749 - 2.8.3.16 0.0000000000000000001033 93.0
PYH1_k127_2374725_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003926 275.0
PYH1_k127_2374725_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000001331 241.0
PYH1_k127_2374725_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000006119 235.0
PYH1_k127_2374725_3 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000007391 239.0
PYH1_k127_2374725_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000003102 208.0
PYH1_k127_2374725_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000002003 199.0
PYH1_k127_2374725_6 PFAM Vitamin B12 dependent methionine synthase, activation domain - - - 0.00000000000000000000000000000000000000000000000005075 187.0
PYH1_k127_241703_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 434.0
PYH1_k127_241703_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 434.0
PYH1_k127_241703_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 407.0
PYH1_k127_241703_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.00000000000000000000000000000000000000000003773 168.0
PYH1_k127_2485217_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
PYH1_k127_2485217_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002841 211.0
PYH1_k127_2485217_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000003746 194.0
PYH1_k127_2485217_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000004899 190.0
PYH1_k127_2485217_4 Dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000006328 179.0
PYH1_k127_2485217_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000001573 152.0
PYH1_k127_2485217_6 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000001321 125.0
PYH1_k127_2485217_7 Conserved hypothetical protein (Lin0512_fam) - - - 0.00000000000000000000003422 102.0
PYH1_k127_2485217_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000006646 60.0
PYH1_k127_2526451_0 hydrogenase large subunit K06281 - 1.12.99.6 1.762e-194 614.0
PYH1_k127_2526451_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 413.0
PYH1_k127_2526451_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000005304 221.0
PYH1_k127_2526759_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 398.0
PYH1_k127_2526759_1 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 293.0
PYH1_k127_2526759_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
PYH1_k127_2526759_3 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000005159 205.0
PYH1_k127_2526759_4 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000001125 137.0
PYH1_k127_2526759_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000002165 137.0
PYH1_k127_2526759_6 peptidase dimerisation domain protein - - - 0.00000002746 56.0
PYH1_k127_2526759_7 - - - - 0.000001012 54.0
PYH1_k127_2541731_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 338.0
PYH1_k127_2541731_1 ABC transporter, ATP-binding protein K01996 - - 0.0000000000000000000000000000000000000002719 152.0
PYH1_k127_2541731_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000001008 140.0
PYH1_k127_256400_0 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 513.0
PYH1_k127_256400_1 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
PYH1_k127_2575146_0 tyrosine recombinase XerC K03733,K04763 - - 0.000000000000000000000000000000006015 145.0
PYH1_k127_2575146_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000009877 108.0
PYH1_k127_2575146_2 Phage integrase SAM-like domain K04763 - - 0.000000000002963 76.0
PYH1_k127_2575146_3 Peptide ABC transporter substrate-binding protein K02035 - - 0.000002346 54.0
PYH1_k127_2644923_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.746e-198 624.0
PYH1_k127_2644923_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 617.0
PYH1_k127_2644923_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 378.0
PYH1_k127_2644923_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
PYH1_k127_2644923_4 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
PYH1_k127_2644923_5 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001549 241.0
PYH1_k127_2644923_6 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000006793 217.0
PYH1_k127_2644923_7 HAD hydrolase, family IA, variant 1 K07025 - - 0.00000000000000000000000000000000000000000000003909 178.0
PYH1_k127_2644923_8 transposition, DNA-mediated - - - 0.0005076 46.0
PYH1_k127_2668852_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 570.0
PYH1_k127_2668852_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 488.0
PYH1_k127_2668852_2 Phage portal protein, SPP1 Gp6-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 285.0
PYH1_k127_2668852_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
PYH1_k127_2668852_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000182 178.0
PYH1_k127_2668852_5 - - - - 0.0000000000000001436 82.0
PYH1_k127_2668852_6 Belongs to the 'phage' integrase family K04763 - - 0.00000000000007812 81.0
PYH1_k127_2682256_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.214e-196 623.0
PYH1_k127_2682256_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000007199 236.0
PYH1_k127_2682256_2 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000001743 203.0
PYH1_k127_2682256_3 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.00000000000000000000000000000000000000000000000000006879 189.0
PYH1_k127_2682256_4 RDD family - - - 0.000000000000000000000005633 107.0
PYH1_k127_2708757_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 572.0
PYH1_k127_2708757_1 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 473.0
PYH1_k127_2708757_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 419.0
PYH1_k127_2708757_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
PYH1_k127_2708757_4 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000004712 214.0
PYH1_k127_2708757_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000003149 189.0
PYH1_k127_2708757_6 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000005436 180.0
PYH1_k127_2708757_7 - - - - 0.0000000000000000001969 99.0
PYH1_k127_2708757_8 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000503 70.0
PYH1_k127_2709234_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 595.0
PYH1_k127_2709234_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 593.0
PYH1_k127_2709234_10 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000003941 231.0
PYH1_k127_2709234_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000003764 115.0
PYH1_k127_2709234_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 464.0
PYH1_k127_2709234_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 436.0
PYH1_k127_2709234_4 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 428.0
PYH1_k127_2709234_5 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 417.0
PYH1_k127_2709234_6 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 348.0
PYH1_k127_2709234_7 DNA modification repair radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 351.0
PYH1_k127_2709234_8 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 320.0
PYH1_k127_2709234_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 300.0
PYH1_k127_2729724_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000371 283.0
PYH1_k127_2729724_1 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002403 241.0
PYH1_k127_2729724_3 Isoprenylcysteine carboxyl methyltransferase - - - 0.000003884 52.0
PYH1_k127_2729724_4 self proteolysis - - - 0.00004961 52.0
PYH1_k127_2741890_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 403.0
PYH1_k127_2741890_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
PYH1_k127_2741890_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000003269 203.0
PYH1_k127_2741890_11 Cytochrome c3 - - - 0.00000000000000000000000000000000001504 148.0
PYH1_k127_2741890_12 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000003028 146.0
PYH1_k127_2741890_13 Response regulator receiver K07696 - - 0.000000000000000000001444 102.0
PYH1_k127_2741890_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000001615 76.0
PYH1_k127_2741890_2 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 294.0
PYH1_k127_2741890_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 269.0
PYH1_k127_2741890_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
PYH1_k127_2741890_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
PYH1_k127_2741890_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007577 271.0
PYH1_k127_2741890_7 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001214 235.0
PYH1_k127_2741890_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000003815 213.0
PYH1_k127_2741890_9 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
PYH1_k127_2768734_0 Belongs to the ClpA ClpB family K03696 - - 1.254e-200 639.0
PYH1_k127_2768734_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 451.0
PYH1_k127_2768734_2 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000001177 246.0
PYH1_k127_2768734_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000009202 217.0
PYH1_k127_2768734_4 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
PYH1_k127_2768734_5 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000007164 142.0
PYH1_k127_2768734_6 PFAM Biotin lipoyl attachment - - - 0.0000000000000474 75.0
PYH1_k127_2792128_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 555.0
PYH1_k127_2792128_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 334.0
PYH1_k127_2792128_2 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 316.0
PYH1_k127_2792128_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000015 148.0
PYH1_k127_2792128_4 acyl-CoA dehydrogenase - - - 0.00000000000002892 75.0
PYH1_k127_2792128_5 Domain of unknown function (DUF1893) - - - 0.0000000000002273 76.0
PYH1_k127_2796293_0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
PYH1_k127_2796293_1 TPM domain K06872 - - 0.00000000000000000000004081 107.0
PYH1_k127_2796293_2 - - - - 0.000007097 54.0
PYH1_k127_2812241_0 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 306.0
PYH1_k127_2812241_1 4Fe-4S single cluster domain K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003638 287.0
PYH1_k127_2812241_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001162 272.0
PYH1_k127_2812241_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004115 248.0
PYH1_k127_2812241_4 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000002657 241.0
PYH1_k127_2812241_5 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000002069 181.0
PYH1_k127_2812241_6 4Fe-4S dicluster domain K05796 - - 0.00000000000000000000000000001039 129.0
PYH1_k127_2812241_7 leucine-rich repeat-containing protein typical subtype K13730 - - 0.00000000000000000000000001818 120.0
PYH1_k127_2812241_8 N-Acetylmuramoyl-L-alanine amidase K01176,K01448,K06385 - 3.2.1.1,3.5.1.28 0.000000143 62.0
PYH1_k127_2864219_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 308.0
PYH1_k127_2864219_1 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005394 259.0
PYH1_k127_2864219_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000007966 231.0
PYH1_k127_2864219_3 Domain of unknown function (DUF4382) - - - 0.0000007925 61.0
PYH1_k127_2869588_0 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004154 276.0
PYH1_k127_2869588_1 - - - - 0.00000000000000000003011 100.0
PYH1_k127_2904474_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 397.0
PYH1_k127_2904474_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000181 251.0
PYH1_k127_2904474_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000001008 211.0
PYH1_k127_2904474_3 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000002875 216.0
PYH1_k127_2904474_4 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000002194 188.0
PYH1_k127_2904474_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000003468 141.0
PYH1_k127_2944841_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 504.0
PYH1_k127_2944841_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 289.0
PYH1_k127_2944841_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000001635 121.0
PYH1_k127_2958603_0 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 371.0
PYH1_k127_2958603_1 ATPase activity K02010,K02017,K02019,K02049,K02068,K02071,K06857,K10112 - 3.6.3.29,3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 350.0
PYH1_k127_2958603_2 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
PYH1_k127_2958603_3 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002587 252.0
PYH1_k127_2958603_4 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008138 245.0
PYH1_k127_2958603_5 - - - - 0.000000000000000000007046 94.0
PYH1_k127_296767_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 473.0
PYH1_k127_296767_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007527 274.0
PYH1_k127_296767_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 264.0
PYH1_k127_296767_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005749 248.0
PYH1_k127_296767_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000002297 192.0
PYH1_k127_3015116_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 7.296e-214 675.0
PYH1_k127_3015116_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 560.0
PYH1_k127_3015116_10 TM2 domain - - - 0.000000000000672 73.0
PYH1_k127_3015116_11 N-terminal half of MaoC dehydratase - - - 0.0000000000007114 70.0
PYH1_k127_3015116_12 Glutaredoxin - - - 0.00008505 48.0
PYH1_k127_3015116_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 434.0
PYH1_k127_3015116_3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
PYH1_k127_3015116_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 312.0
PYH1_k127_3015116_5 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 306.0
PYH1_k127_3015116_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 270.0
PYH1_k127_3015116_7 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K02617 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.0000000000000000000000000000000000002542 146.0
PYH1_k127_3015116_8 MaoC like domain - - - 0.00000000000000000000000000000002717 131.0
PYH1_k127_3015116_9 Thioredoxin - - - 0.0000000000000000000000000001525 123.0
PYH1_k127_3029945_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.119e-243 761.0
PYH1_k127_3029945_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.095e-219 694.0
PYH1_k127_3029945_10 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000001964 201.0
PYH1_k127_3029945_11 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000001808 181.0
PYH1_k127_3029945_12 Bifunctional coenzyme A synthase K02318 GO:0000003,GO:0001667,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003006,GO:0003674,GO:0003824,GO:0004140,GO:0004595,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005759,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007300,GO:0007303,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0010631,GO:0015936,GO:0015937,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016482,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019867,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040011,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046390,GO:0046483,GO:0046907,GO:0048468,GO:0048477,GO:0048513,GO:0048563,GO:0048569,GO:0048609,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0055086,GO:0055088,GO:0055090,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070013,GO:0070328,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090130,GO:0090132,GO:0090407,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.3 0.0000000000000000000000000000000000000000000004224 173.0
PYH1_k127_3029945_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000001289 174.0
PYH1_k127_3029945_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000002974 159.0
PYH1_k127_3029945_15 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000004212 159.0
PYH1_k127_3029945_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000008199 141.0
PYH1_k127_3029945_17 - - - - 0.000000000000000000000000000002536 121.0
PYH1_k127_3029945_18 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000007462 117.0
PYH1_k127_3029945_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000007593 119.0
PYH1_k127_3029945_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 524.0
PYH1_k127_3029945_20 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000001161 115.0
PYH1_k127_3029945_21 - - - - 0.0000000006732 61.0
PYH1_k127_3029945_22 - - - - 0.00000001572 58.0
PYH1_k127_3029945_3 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 316.0
PYH1_k127_3029945_4 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
PYH1_k127_3029945_5 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 292.0
PYH1_k127_3029945_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004941 275.0
PYH1_k127_3029945_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000655 231.0
PYH1_k127_3029945_8 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000004942 215.0
PYH1_k127_3029945_9 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000004894 222.0
PYH1_k127_3065_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000002518 185.0
PYH1_k127_3065_1 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000000000000001049 189.0
PYH1_k127_3065_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000004928 169.0
PYH1_k127_3181707_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 508.0
PYH1_k127_3181707_1 Hypothetical methyltransferase - - - 0.00000000000000000000015 105.0
PYH1_k127_3217673_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
PYH1_k127_3217673_1 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000009473 209.0
PYH1_k127_3217673_2 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000003834 192.0
PYH1_k127_3217673_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000006924 133.0
PYH1_k127_3217673_4 Subtilase family K01342 - 3.4.21.62 0.000000000000000001844 88.0
PYH1_k127_3217673_5 - - - - 0.00000819 53.0
PYH1_k127_3240195_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 576.0
PYH1_k127_3240195_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001098 251.0
PYH1_k127_3240195_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000916 236.0
PYH1_k127_32519_0 Radical SAM N-terminal - - - 4.715e-274 852.0
PYH1_k127_32519_1 Conserved region in glutamate synthase - - - 8.712e-262 812.0
PYH1_k127_32519_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 253.0
PYH1_k127_32519_11 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000001509 229.0
PYH1_k127_32519_12 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000008709 192.0
PYH1_k127_32519_13 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 - - 0.000000000000000000000000000000000000000000000005194 176.0
PYH1_k127_32519_15 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000128 153.0
PYH1_k127_32519_16 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000005643 148.0
PYH1_k127_32519_17 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000003966 128.0
PYH1_k127_32519_18 amidohydrolase K07045 - - 0.0000000000000000000000000005909 126.0
PYH1_k127_32519_19 PFAM Nitroreductase - - - 0.000000000000000000000000007143 117.0
PYH1_k127_32519_2 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.066e-257 801.0
PYH1_k127_32519_20 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.0000000000000000001466 96.0
PYH1_k127_32519_21 regulatory protein, FmdB family - - - 0.0000000000000000188 84.0
PYH1_k127_32519_22 - - - - 0.000000000007872 72.0
PYH1_k127_32519_23 Regulatory protein, FmdB family - - - 0.00000009682 56.0
PYH1_k127_32519_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 7.327e-220 688.0
PYH1_k127_32519_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 617.0
PYH1_k127_32519_5 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 562.0
PYH1_k127_32519_6 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 548.0
PYH1_k127_32519_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 414.0
PYH1_k127_32519_8 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
PYH1_k127_32519_9 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006588 282.0
PYH1_k127_3261701_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 500.0
PYH1_k127_3261701_1 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 496.0
PYH1_k127_3261701_2 PFAM Integrase catalytic region K07497 - - 0.00000000000000000002488 91.0
PYH1_k127_3261701_3 Probable zinc-ribbon domain - - - 0.0000000000000005378 79.0
PYH1_k127_3261701_4 PFAM Integrase catalytic region K07497 - - 0.0000000000006844 68.0
PYH1_k127_3261701_5 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000004444 65.0
PYH1_k127_3261701_6 - - - - 0.0000004634 57.0
PYH1_k127_3261701_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00004708 49.0
PYH1_k127_3299814_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.938e-297 923.0
PYH1_k127_3299814_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 447.0
PYH1_k127_3299814_10 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000002527 198.0
PYH1_k127_3299814_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000006077 186.0
PYH1_k127_3299814_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000006312 119.0
PYH1_k127_3299814_13 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000004708 74.0
PYH1_k127_3299814_14 - - - - 0.0000000006944 63.0
PYH1_k127_3299814_15 COG3291 FOG PKD repeat - - - 0.0001465 53.0
PYH1_k127_3299814_2 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 434.0
PYH1_k127_3299814_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 436.0
PYH1_k127_3299814_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 348.0
PYH1_k127_3299814_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 315.0
PYH1_k127_3299814_6 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008668 277.0
PYH1_k127_3299814_7 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH1_k127_3299814_8 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
PYH1_k127_3299814_9 MatE - - - 0.0000000000000000000000000000000000000000000000000001635 199.0
PYH1_k127_331475_0 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 523.0
PYH1_k127_331475_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 427.0
PYH1_k127_331475_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 406.0
PYH1_k127_331475_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 407.0
PYH1_k127_331475_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 396.0
PYH1_k127_331475_5 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 383.0
PYH1_k127_331475_6 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 353.0
PYH1_k127_331475_7 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.000000000000000000000000001658 116.0
PYH1_k127_33555_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 297.0
PYH1_k127_33555_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
PYH1_k127_33555_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000004273 123.0
PYH1_k127_33555_3 peptidase U32 - - - 0.00000000000000000000000004012 109.0
PYH1_k127_3389752_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 301.0
PYH1_k127_3389752_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 292.0
PYH1_k127_3389752_2 - - - - 0.0000000000000000000000000000000000000000000000001178 189.0
PYH1_k127_3389752_3 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000004209 133.0
PYH1_k127_3389752_4 OsmC-like protein K07397 - - 0.000000000000000000003776 101.0
PYH1_k127_3389752_5 Zinc ribbon domain - - - 0.0000000000013 70.0
PYH1_k127_3389752_7 - - - - 0.000001425 59.0
PYH1_k127_3441480_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.986e-196 623.0
PYH1_k127_3441480_1 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
PYH1_k127_3441480_2 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000024 168.0
PYH1_k127_3461476_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.395e-221 704.0
PYH1_k127_3461476_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 507.0
PYH1_k127_3461476_10 4Fe-4S dicluster domain K05580 - 1.6.5.3 0.0000000000000000000000000000000005189 136.0
PYH1_k127_3461476_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.00000000000000000000000000000001001 130.0
PYH1_k127_3461476_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000004913 124.0
PYH1_k127_3461476_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 488.0
PYH1_k127_3461476_3 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 394.0
PYH1_k127_3461476_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 391.0
PYH1_k127_3461476_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 363.0
PYH1_k127_3461476_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 332.0
PYH1_k127_3461476_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005524 263.0
PYH1_k127_3461476_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
PYH1_k127_3461476_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000003076 148.0
PYH1_k127_3480782_0 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 285.0
PYH1_k127_3480782_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007191 274.0
PYH1_k127_3480782_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000001075 178.0
PYH1_k127_3480782_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000007023 66.0
PYH1_k127_3512631_0 Oligopeptidase F K08602 - - 2.961e-202 644.0
PYH1_k127_3512631_1 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000001057 189.0
PYH1_k127_3512631_2 - - - - 0.00003019 51.0
PYH1_k127_3523141_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 501.0
PYH1_k127_3523141_1 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
PYH1_k127_3523141_2 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000001106 201.0
PYH1_k127_3523141_3 GDP-mannose 4,6 dehydratase K00091 - 1.1.1.219 0.0000000000000000000000009477 107.0
PYH1_k127_3523141_4 GYD domain - - - 0.000000000000000008087 87.0
PYH1_k127_3523141_5 - - - - 0.0000002329 56.0
PYH1_k127_352411_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 3.912e-201 633.0
PYH1_k127_352411_1 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000624 243.0
PYH1_k127_352411_2 GrpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000001418 218.0
PYH1_k127_352411_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000002535 219.0
PYH1_k127_352411_4 KR domain K07124 - - 0.000000000000000000000000000000000000000000000000000001133 203.0
PYH1_k127_352411_5 DsrE/DsrF-like family K04085 - - 0.00000000000000000000000001255 112.0
PYH1_k127_352411_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000002961 74.0
PYH1_k127_357604_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003213 283.0
PYH1_k127_357604_1 AMP binding - - - 0.00000000000000000009757 96.0
PYH1_k127_357604_2 PFAM multi antimicrobial extrusion protein - - - 0.000000000000000001159 91.0
PYH1_k127_3578471_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 620.0
PYH1_k127_3578471_1 Radical SAM superfamily K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 518.0
PYH1_k127_3578471_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 387.0
PYH1_k127_3578471_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 311.0
PYH1_k127_3578471_4 PhoQ Sensor K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001239 207.0
PYH1_k127_3578471_5 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000007716 189.0
PYH1_k127_3578471_6 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000003972 148.0
PYH1_k127_3578471_7 cheY-homologous receiver domain - - - 0.000000000000000000000001064 109.0
PYH1_k127_3578471_8 PFAM response regulator receiver - - - 0.00000000000000000000002242 106.0
PYH1_k127_3578471_9 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000002498 76.0
PYH1_k127_3610297_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 7e-323 1006.0
PYH1_k127_3610297_1 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 297.0
PYH1_k127_3610297_2 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000004677 229.0
PYH1_k127_3610297_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000007038 189.0
PYH1_k127_3610297_4 Transcriptional regulator - - - 0.00000000000000000006359 96.0
PYH1_k127_3610297_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04079 - - 0.000001062 59.0
PYH1_k127_3618958_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 555.0
PYH1_k127_3618958_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 354.0
PYH1_k127_3618958_10 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000312 162.0
PYH1_k127_3618958_11 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000001798 171.0
PYH1_k127_3618958_12 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000003811 134.0
PYH1_k127_3618958_13 PFAM ABC-2 type transporter K01992 - - 0.000000000000000005813 96.0
PYH1_k127_3618958_14 - - - - 0.00000000001318 67.0
PYH1_k127_3618958_15 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00002471 48.0
PYH1_k127_3618958_2 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 330.0
PYH1_k127_3618958_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 299.0
PYH1_k127_3618958_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001833 261.0
PYH1_k127_3618958_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001359 244.0
PYH1_k127_3618958_6 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
PYH1_k127_3618958_7 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K17735 - 1.1.1.108,1.1.1.157 0.000000000000000000000000000000000000000000000000000000002726 207.0
PYH1_k127_3618958_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000002596 195.0
PYH1_k127_3618958_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000001098 175.0
PYH1_k127_3622994_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1405.0
PYH1_k127_3622994_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.443e-280 884.0
PYH1_k127_3622994_10 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002306 229.0
PYH1_k127_3622994_11 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000000001676 209.0
PYH1_k127_3622994_12 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000007233 203.0
PYH1_k127_3622994_13 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000008513 188.0
PYH1_k127_3622994_14 -acetyltransferase - - - 0.0000000000000000000000000001886 119.0
PYH1_k127_3622994_15 sulfur carrier activity - - - 0.0000000000000000000000001746 107.0
PYH1_k127_3622994_16 glutaredoxin-like protein, YruB-family - - - 0.000000000000000000002035 94.0
PYH1_k127_3622994_17 - - - - 0.000000000000000227 81.0
PYH1_k127_3622994_18 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000001418 72.0
PYH1_k127_3622994_19 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000006938 64.0
PYH1_k127_3622994_2 elongation factor Tu domain 2 protein K02355 - - 4.64e-196 632.0
PYH1_k127_3622994_20 SNARE associated Golgi protein - - - 0.00001286 48.0
PYH1_k127_3622994_3 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 557.0
PYH1_k127_3622994_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 486.0
PYH1_k127_3622994_5 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 445.0
PYH1_k127_3622994_6 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 400.0
PYH1_k127_3622994_7 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 336.0
PYH1_k127_3622994_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000004022 259.0
PYH1_k127_3622994_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
PYH1_k127_3626271_0 AAA-like domain K06915 - - 6.579e-226 712.0
PYH1_k127_3626271_1 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 322.0
PYH1_k127_3626271_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000004203 227.0
PYH1_k127_3626271_3 PFAM HAS barrel domain - - - 0.0000000000000000000000000000000000000000000000000001972 191.0
PYH1_k127_3626271_4 LysE type translocator - - - 0.000000000000001424 77.0
PYH1_k127_3648819_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000001157 273.0
PYH1_k127_3648819_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000007653 196.0
PYH1_k127_3691275_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 401.0
PYH1_k127_3691275_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 376.0
PYH1_k127_3691275_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 311.0
PYH1_k127_3691275_3 methyltransferase activity - - - 0.0003683 45.0
PYH1_k127_3738_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 6.392e-206 650.0
PYH1_k127_3738_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002634 277.0
PYH1_k127_3738_2 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000006435 271.0
PYH1_k127_3738_3 Alpha/beta hydrolase family K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000007148 241.0
PYH1_k127_3738_4 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000009203 204.0
PYH1_k127_3738_5 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000008325 171.0
PYH1_k127_3738_6 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000001898 167.0
PYH1_k127_3738_7 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000000000000005751 117.0
PYH1_k127_3738_8 CoA-transferase family III - - - 0.00000000001582 67.0
PYH1_k127_3738_9 PFAM regulatory protein TetR - - - 0.00000000001683 72.0
PYH1_k127_3747497_0 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
PYH1_k127_3747497_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000002112 246.0
PYH1_k127_3747497_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000004099 218.0
PYH1_k127_381970_0 succinate dehydrogenase K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 379.0
PYH1_k127_381970_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
PYH1_k127_381970_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000002162 93.0
PYH1_k127_381970_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000125 68.0
PYH1_k127_3825344_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 375.0
PYH1_k127_3825344_1 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 287.0
PYH1_k127_3825344_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009803 276.0
PYH1_k127_3825344_3 Pfam:N_methyl_2 K02650 - - 0.000000000000001657 81.0
PYH1_k127_3825344_4 PFAM multicopper oxidase type 2 - - - 0.00000000000001055 76.0
PYH1_k127_3880564_0 Belongs to the OprB family K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002993 294.0
PYH1_k127_3880564_1 Ion transport 2 domain protein - - - 0.0000000000000000000000001008 109.0
PYH1_k127_3880564_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000003925 78.0
PYH1_k127_3880564_3 Putative MetA-pathway of phenol degradation - - - 0.00000361 53.0
PYH1_k127_3952622_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001038 235.0
PYH1_k127_3952622_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000003739 209.0
PYH1_k127_3952622_2 SnoaL-like polyketide cyclase K06893 - - 0.00000000000000000001209 96.0
PYH1_k127_3952622_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000995 78.0
PYH1_k127_3952622_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000004458 63.0
PYH1_k127_3952622_5 Dimerisation domain - - - 0.000000006744 64.0
PYH1_k127_3952622_6 Protein of unknown function (DUF998) - - - 0.000002665 57.0
PYH1_k127_3971539_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 1.81e-286 893.0
PYH1_k127_3971539_1 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 428.0
PYH1_k127_3971539_2 Dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 318.0
PYH1_k127_3971539_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
PYH1_k127_3971539_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002566 284.0
PYH1_k127_3971539_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000002884 180.0
PYH1_k127_3971539_6 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000001252 136.0
PYH1_k127_3971539_7 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.0000000000000000000006807 98.0
PYH1_k127_4059362_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 561.0
PYH1_k127_4059362_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 334.0
PYH1_k127_4059362_2 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
PYH1_k127_4059362_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH1_k127_4059362_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000003652 216.0
PYH1_k127_4059362_5 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000001098 82.0
PYH1_k127_4059362_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000002346 82.0
PYH1_k127_4068735_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 315.0
PYH1_k127_4068735_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000003374 165.0
PYH1_k127_4068735_2 Amino acid permease - - - 0.0000000000000000000000004361 110.0
PYH1_k127_4068735_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000006648 85.0
PYH1_k127_4069947_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.002e-249 787.0
PYH1_k127_4069947_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 428.0
PYH1_k127_4069947_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000005845 205.0
PYH1_k127_4069947_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000412 181.0
PYH1_k127_4069947_4 Phospholipid methyltransferase - - - 0.0000000000000000003791 93.0
PYH1_k127_40854_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 364.0
PYH1_k127_40854_1 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000000000000001597 134.0
PYH1_k127_40854_2 HemY domain protein K02498 - - 0.0000000000004449 68.0
PYH1_k127_4199586_0 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008076 281.0
PYH1_k127_4199586_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009501 271.0
PYH1_k127_4199586_2 Phosphotriesterase family K07048 - - 0.0000000000000006585 82.0
PYH1_k127_4199586_3 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.0000001319 53.0
PYH1_k127_4255642_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.228e-220 694.0
PYH1_k127_4255642_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.826e-195 616.0
PYH1_k127_4255642_10 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000002595 95.0
PYH1_k127_4255642_11 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000001528 90.0
PYH1_k127_4255642_12 MgtC family K07507 - - 0.00000000000000008583 81.0
PYH1_k127_4255642_13 GIY-YIG catalytic domain K07461 - - 0.000000000000003748 76.0
PYH1_k127_4255642_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000001235 87.0
PYH1_k127_4255642_15 Nitroreductase family K04719 - 1.13.11.79 0.00000000000004362 79.0
PYH1_k127_4255642_16 GIY-YIG catalytic domain K07461 - - 0.00000000002045 64.0
PYH1_k127_4255642_17 HlyD family secretion protein K02005 - - 0.00003308 57.0
PYH1_k127_4255642_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 510.0
PYH1_k127_4255642_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 463.0
PYH1_k127_4255642_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 409.0
PYH1_k127_4255642_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 366.0
PYH1_k127_4255642_6 Efflux ABC transporter permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 329.0
PYH1_k127_4255642_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007797 269.0
PYH1_k127_4255642_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001982 254.0
PYH1_k127_4255642_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000007695 109.0
PYH1_k127_4257613_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.624e-313 970.0
PYH1_k127_4257613_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.893e-296 935.0
PYH1_k127_4257613_10 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 321.0
PYH1_k127_4257613_11 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 313.0
PYH1_k127_4257613_12 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 310.0
PYH1_k127_4257613_13 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 307.0
PYH1_k127_4257613_14 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 280.0
PYH1_k127_4257613_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000001741 179.0
PYH1_k127_4257613_16 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000003471 184.0
PYH1_k127_4257613_18 - - - - 0.0000005566 61.0
PYH1_k127_4257613_2 Domain of unknown function (DUF3536) - - - 2.731e-267 844.0
PYH1_k127_4257613_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.355e-243 769.0
PYH1_k127_4257613_4 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 599.0
PYH1_k127_4257613_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 479.0
PYH1_k127_4257613_6 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 470.0
PYH1_k127_4257613_7 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 442.0
PYH1_k127_4257613_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 444.0
PYH1_k127_4257613_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 395.0
PYH1_k127_4286989_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1113.0
PYH1_k127_4286989_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 440.0
PYH1_k127_4286989_10 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000001819 178.0
PYH1_k127_4286989_11 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000001632 163.0
PYH1_k127_4286989_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000006686 133.0
PYH1_k127_4286989_13 AMP binding - - - 0.000000000000000000000000001028 118.0
PYH1_k127_4286989_14 Regulatory protein, FmdB family - - - 0.000009161 49.0
PYH1_k127_4286989_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 373.0
PYH1_k127_4286989_3 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 357.0
PYH1_k127_4286989_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 357.0
PYH1_k127_4286989_5 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 344.0
PYH1_k127_4286989_6 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 315.0
PYH1_k127_4286989_7 cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
PYH1_k127_4286989_8 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
PYH1_k127_4286989_9 PFAM GDSL-like Lipase Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000006387 190.0
PYH1_k127_4319240_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
PYH1_k127_4319240_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003591 278.0
PYH1_k127_4319240_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003644 274.0
PYH1_k127_4319240_3 Chloramphenicol phosphotransferase-like protein K18554 - - 0.00000000000000000000000000000000000000000002228 168.0
PYH1_k127_4319240_4 PFAM Integrase catalytic region K07497 - - 0.0000001749 55.0
PYH1_k127_433311_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 6.899e-234 738.0
PYH1_k127_433311_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 312.0
PYH1_k127_433311_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000009042 173.0
PYH1_k127_433311_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000000005813 140.0
PYH1_k127_433311_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000008275 138.0
PYH1_k127_433311_5 GGDEF domain - - - 0.0000000001443 63.0
PYH1_k127_43424_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 4.176e-203 642.0
PYH1_k127_43424_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 314.0
PYH1_k127_43424_10 - - - - 0.00000000000000000000005159 110.0
PYH1_k127_43424_11 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000002002 74.0
PYH1_k127_43424_12 - - - - 0.0000000000001234 73.0
PYH1_k127_43424_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 310.0
PYH1_k127_43424_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
PYH1_k127_43424_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000915 198.0
PYH1_k127_43424_5 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000002633 194.0
PYH1_k127_43424_6 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000008344 168.0
PYH1_k127_43424_7 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000000000000004632 140.0
PYH1_k127_43424_8 GH3 auxin-responsive promoter - - - 0.000000000000000000000002348 117.0
PYH1_k127_43424_9 Methanol dehydrogenase K06872 - - 0.00000000000000000000002799 104.0
PYH1_k127_4348395_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1729.0
PYH1_k127_4348395_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1416.0
PYH1_k127_4348395_10 - - - - 0.00000002409 61.0
PYH1_k127_4348395_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 8.607e-204 651.0
PYH1_k127_4348395_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 490.0
PYH1_k127_4348395_4 IMP dehydrogenase / GMP reductase domain K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH1_k127_4348395_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 328.0
PYH1_k127_4348395_6 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000003505 211.0
PYH1_k127_4348395_7 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000002253 195.0
PYH1_k127_4348395_8 Chromatin associated protein KTI12 - - - 0.000000000000000000000000000000000003287 144.0
PYH1_k127_4348395_9 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000004013 89.0
PYH1_k127_4363008_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.728e-217 691.0
PYH1_k127_4363008_1 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 470.0
PYH1_k127_4363008_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000009373 185.0
PYH1_k127_4382667_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000001301 228.0
PYH1_k127_4382667_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000002729 158.0
PYH1_k127_4382667_2 KR domain K13774 - - 0.0000000001539 62.0
PYH1_k127_4404092_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 568.0
PYH1_k127_4404092_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 491.0
PYH1_k127_4404092_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 446.0
PYH1_k127_4404092_3 sAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000001618 194.0
PYH1_k127_4404092_4 NUDIX domain - - - 0.000000000000000000000000000001225 128.0
PYH1_k127_4404092_5 HupF/HypC family K04653 - - 0.000000000000000004345 85.0
PYH1_k127_4428845_0 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 454.0
PYH1_k127_4487211_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 613.0
PYH1_k127_4487211_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 408.0
PYH1_k127_4487211_2 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 378.0
PYH1_k127_4487211_3 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003736 263.0
PYH1_k127_4487211_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002965 263.0
PYH1_k127_4487211_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000002323 252.0
PYH1_k127_4487211_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000114 128.0
PYH1_k127_4487211_7 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0000000000000000000000000000007313 123.0
PYH1_k127_4496410_0 DNA ligase K01971 - 6.5.1.1 1.149e-249 799.0
PYH1_k127_4496410_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 339.0
PYH1_k127_4496410_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000005194 193.0
PYH1_k127_4496410_3 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000004399 169.0
PYH1_k127_4496410_4 Glycosyltransferase family 87 - - - 0.0000000000000000001557 102.0
PYH1_k127_4496410_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000002188 69.0
PYH1_k127_449747_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 469.0
PYH1_k127_449747_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 301.0
PYH1_k127_449747_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000001146 133.0
PYH1_k127_449747_11 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000002463 108.0
PYH1_k127_449747_12 NifU-like domain - - - 0.000000000001779 67.0
PYH1_k127_449747_13 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000003653 58.0
PYH1_k127_449747_14 NifU-like domain - - - 0.00001323 47.0
PYH1_k127_449747_2 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
PYH1_k127_449747_3 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000009515 214.0
PYH1_k127_449747_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000009977 200.0
PYH1_k127_449747_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000004092 191.0
PYH1_k127_449747_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000004346 176.0
PYH1_k127_449747_7 Glycoprotease family - - - 0.000000000000000000000000000000000000000000000007032 181.0
PYH1_k127_449747_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000006226 168.0
PYH1_k127_449747_9 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002621 164.0
PYH1_k127_450435_0 Aromatic ring hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.318e-205 652.0
PYH1_k127_450435_1 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 466.0
PYH1_k127_450435_2 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 460.0
PYH1_k127_4521402_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 386.0
PYH1_k127_4521402_1 - - - - 0.000000000000000000000000000000000000000005868 157.0
PYH1_k127_4521402_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000003617 140.0
PYH1_k127_4560853_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 544.0
PYH1_k127_4560853_1 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 537.0
PYH1_k127_4560853_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 381.0
PYH1_k127_4560853_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 367.0
PYH1_k127_4560853_4 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 321.0
PYH1_k127_4560853_5 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001564 289.0
PYH1_k127_4560853_6 acetyl coenzyme A synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 287.0
PYH1_k127_4560853_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001703 263.0
PYH1_k127_4560853_8 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000001525 171.0
PYH1_k127_4560853_9 Carboxymuconolactone decarboxylase family - - - 0.0000000000000003647 83.0
PYH1_k127_45919_0 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001324 294.0
PYH1_k127_45919_1 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000000001263 193.0
PYH1_k127_45919_2 - - - - 0.000158 45.0
PYH1_k127_4642155_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 559.0
PYH1_k127_4642155_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 459.0
PYH1_k127_4642155_10 Enoyl-CoA hydratase/isomerase K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000004789 148.0
PYH1_k127_4642155_11 response regulator - - - 0.00000000000000000000000000005152 123.0
PYH1_k127_4642155_12 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000005793 100.0
PYH1_k127_4642155_2 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 351.0
PYH1_k127_4642155_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
PYH1_k127_4642155_4 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
PYH1_k127_4642155_5 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
PYH1_k127_4642155_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001661 237.0
PYH1_k127_4642155_7 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000009997 199.0
PYH1_k127_4642155_8 - K07018 - - 0.00000000000000000000000000000000000000000000003817 179.0
PYH1_k127_4642155_9 PFAM NADH flavin oxidoreductase NADH oxidase K10797 - 1.3.1.31 0.0000000000000000000000000000000000000003649 160.0
PYH1_k127_4653310_0 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 355.0
PYH1_k127_4653310_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000002372 199.0
PYH1_k127_4653310_2 Transposase K07491 - - 0.000000000000000000000000000000000000009675 149.0
PYH1_k127_4653310_3 Nacht domain - - - 0.000000000000001047 80.0
PYH1_k127_4667407_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
PYH1_k127_4667407_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000216 245.0
PYH1_k127_4667407_2 Replication initiation and membrane attachment - - - 0.00000000000000000000000000000000000000000000000000001739 198.0
PYH1_k127_4667407_3 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001808 143.0
PYH1_k127_4725010_1 Protein of unknown function (DUF2628) - - - 0.000000000000000000000000002073 116.0
PYH1_k127_4725010_2 IMP dehydrogenase activity K07182 - - 0.00000000000000000000005019 104.0
PYH1_k127_4725010_3 - - - - 0.000000007796 57.0
PYH1_k127_4738577_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1167.0
PYH1_k127_476302_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 346.0
PYH1_k127_476302_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002667 197.0
PYH1_k127_476302_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000004666 128.0
PYH1_k127_476302_3 - - - - 0.0000000000000000000022 96.0
PYH1_k127_476302_4 CAAX protease self-immunity K07052 - - 0.000000000000000000004598 103.0
PYH1_k127_476302_5 Domain of unknown function (DU1801) - - - 0.0000000000000002271 83.0
PYH1_k127_481232_0 Aminotransferase class I and II K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 556.0
PYH1_k127_481232_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 462.0
PYH1_k127_481232_10 RNA recognition motif - - - 0.0000000000000000000000000000001802 126.0
PYH1_k127_481232_11 SpoVT / AbrB like domain - - - 0.0000000001449 66.0
PYH1_k127_481232_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 426.0
PYH1_k127_481232_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 418.0
PYH1_k127_481232_4 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 403.0
PYH1_k127_481232_5 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 302.0
PYH1_k127_481232_6 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000007604 243.0
PYH1_k127_481232_7 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
PYH1_k127_481232_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001154 178.0
PYH1_k127_481232_9 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000009944 164.0
PYH1_k127_497696_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 493.0
PYH1_k127_497696_1 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000004969 218.0
PYH1_k127_5029137_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 354.0
PYH1_k127_5029137_1 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 336.0
PYH1_k127_5029137_2 PFAM Transketolase K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000357 229.0
PYH1_k127_5029137_3 KR domain - - - 0.000000000000000000000000000000000000000000000001339 184.0
PYH1_k127_5043179_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 1.094e-305 947.0
PYH1_k127_5043179_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 535.0
PYH1_k127_5044982_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.07e-269 839.0
PYH1_k127_5044982_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.121e-262 819.0
PYH1_k127_5044982_10 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
PYH1_k127_5044982_11 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 329.0
PYH1_k127_5044982_12 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 311.0
PYH1_k127_5044982_13 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002065 286.0
PYH1_k127_5044982_14 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000159 258.0
PYH1_k127_5044982_15 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000001573 225.0
PYH1_k127_5044982_16 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000491 226.0
PYH1_k127_5044982_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
PYH1_k127_5044982_18 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000007623 212.0
PYH1_k127_5044982_19 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000001871 185.0
PYH1_k127_5044982_2 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 6.897e-235 737.0
PYH1_k127_5044982_20 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000002359 186.0
PYH1_k127_5044982_21 denitrification pathway - - - 0.00000000000000000000000000000000000000000000004332 178.0
PYH1_k127_5044982_22 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000005206 175.0
PYH1_k127_5044982_23 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000003643 162.0
PYH1_k127_5044982_24 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.0000000000000000000000000000000000000002834 155.0
PYH1_k127_5044982_25 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000003021 158.0
PYH1_k127_5044982_26 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000003253 149.0
PYH1_k127_5044982_27 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000003874 148.0
PYH1_k127_5044982_28 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000187 137.0
PYH1_k127_5044982_29 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000000000004355 142.0
PYH1_k127_5044982_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.338e-228 715.0
PYH1_k127_5044982_30 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000008635 126.0
PYH1_k127_5044982_31 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.000000000000000000000000000002037 121.0
PYH1_k127_5044982_32 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000976 127.0
PYH1_k127_5044982_33 MgtC family K07507 - - 0.0000000000000000000000000003887 116.0
PYH1_k127_5044982_34 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000001198 100.0
PYH1_k127_5044982_35 Belongs to the UPF0434 family - - - 0.000000000000000007103 85.0
PYH1_k127_5044982_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.012e-207 654.0
PYH1_k127_5044982_5 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 571.0
PYH1_k127_5044982_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 547.0
PYH1_k127_5044982_7 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 480.0
PYH1_k127_5044982_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 447.0
PYH1_k127_5044982_9 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 361.0
PYH1_k127_5094631_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 441.0
PYH1_k127_5094631_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 386.0
PYH1_k127_5094631_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 258.0
PYH1_k127_5094631_3 PFAM HD domain - - - 0.000000000000000000000000000000000000000000005096 170.0
PYH1_k127_5094631_4 - - - - 0.000000000001189 70.0
PYH1_k127_5094631_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000003788 63.0
PYH1_k127_5094631_6 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00001004 51.0
PYH1_k127_5101345_0 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 332.0
PYH1_k127_5101345_1 Ribonuclease R winged-helix domain protein K09720 - - 0.00000000000000000000004305 101.0
PYH1_k127_5123907_0 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 413.0
PYH1_k127_5123907_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 387.0
PYH1_k127_5123907_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 292.0
PYH1_k127_5123907_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0008138 45.0
PYH1_k127_5166937_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.149e-309 971.0
PYH1_k127_5166937_1 Domain of unknown function (DUF4131) K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 563.0
PYH1_k127_5166937_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001062 286.0
PYH1_k127_5166937_3 COG2015, Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009295 266.0
PYH1_k127_5166937_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000002533 182.0
PYH1_k127_5166937_5 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000001023 116.0
PYH1_k127_5166937_6 RDD family - - - 0.0000000000000000000000004971 105.0
PYH1_k127_5168533_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 499.0
PYH1_k127_5168533_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000004329 183.0
PYH1_k127_5168533_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000002298 175.0
PYH1_k127_5168533_3 ethyl tert-butyl ether degradation - - - 0.0000000000000000000008514 98.0
PYH1_k127_5168533_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000001587 68.0
PYH1_k127_5184019_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
PYH1_k127_5184019_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000001005 148.0
PYH1_k127_5184019_2 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000002598 148.0
PYH1_k127_5186017_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 427.0
PYH1_k127_5186017_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K22338 - 1.17.1.11 0.000000000000000000000000000000000000000000000000000004262 198.0
PYH1_k127_5186017_2 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000000147 185.0
PYH1_k127_5186017_3 NADH-quinone oxidoreductase, E subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000003636 122.0
PYH1_k127_5186017_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000004202 59.0
PYH1_k127_5188180_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1146.0
PYH1_k127_5188180_1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 7.361e-225 712.0
PYH1_k127_5188180_10 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
PYH1_k127_5188180_11 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002571 269.0
PYH1_k127_5188180_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009215 237.0
PYH1_k127_5188180_13 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055,K01259,K09023,K14727,K16434 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.1.1.24,3.4.11.5,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000003348 236.0
PYH1_k127_5188180_14 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000512 235.0
PYH1_k127_5188180_15 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000002239 203.0
PYH1_k127_5188180_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000003171 207.0
PYH1_k127_5188180_17 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000002263 176.0
PYH1_k127_5188180_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000001862 151.0
PYH1_k127_5188180_19 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000002956 149.0
PYH1_k127_5188180_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
PYH1_k127_5188180_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000001846 110.0
PYH1_k127_5188180_21 FR47-like protein - - - 0.0000000000000000001597 95.0
PYH1_k127_5188180_22 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000001179 81.0
PYH1_k127_5188180_24 DSBA-like thioredoxin domain - - - 0.000001487 57.0
PYH1_k127_5188180_3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 409.0
PYH1_k127_5188180_4 enoyl-(acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
PYH1_k127_5188180_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 351.0
PYH1_k127_5188180_6 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
PYH1_k127_5188180_7 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 330.0
PYH1_k127_5188180_8 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 289.0
PYH1_k127_5188180_9 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002047 281.0
PYH1_k127_521577_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 602.0
PYH1_k127_521577_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 596.0
PYH1_k127_521577_2 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 398.0
PYH1_k127_521577_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 314.0
PYH1_k127_521577_4 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
PYH1_k127_521577_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
PYH1_k127_521577_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000002106 190.0
PYH1_k127_521577_7 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000003096 131.0
PYH1_k127_5228531_0 AMP-binding enzyme K01897 - 6.2.1.3 5.235e-226 709.0
PYH1_k127_5228531_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 291.0
PYH1_k127_5228531_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000007954 244.0
PYH1_k127_5228531_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000007258 208.0
PYH1_k127_5228531_4 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.0000000000000000000000001232 113.0
PYH1_k127_5251768_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 478.0
PYH1_k127_5251768_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 389.0
PYH1_k127_5251768_10 Cyclic nucleotide-monophosphate binding domain - - - 0.0000004448 58.0
PYH1_k127_5251768_11 LacY proton/sugar symporter - - - 0.00002387 48.0
PYH1_k127_5251768_12 helix_turn_helix, Lux Regulon - - - 0.00007607 53.0
PYH1_k127_5251768_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
PYH1_k127_5251768_3 helix_turn_helix, Lux Regulon K11618 - - 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
PYH1_k127_5251768_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000001044 217.0
PYH1_k127_5251768_5 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000001691 201.0
PYH1_k127_5251768_6 Protein of unknown function (DUF402) K09145 - - 0.0000000000000000000000000000000000003087 148.0
PYH1_k127_5251768_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000539 94.0
PYH1_k127_5251768_8 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000001791 94.0
PYH1_k127_5251768_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000269 69.0
PYH1_k127_5259566_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 564.0
PYH1_k127_5259566_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 512.0
PYH1_k127_5259566_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
PYH1_k127_5259566_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 377.0
PYH1_k127_5259566_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 325.0
PYH1_k127_5259566_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007573 226.0
PYH1_k127_5259566_6 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000005587 151.0
PYH1_k127_5259566_7 - - - - 0.0000000000000000000000000000000000001648 144.0
PYH1_k127_5259566_8 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000004338 96.0
PYH1_k127_5259566_9 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000007625 51.0
PYH1_k127_5347532_0 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 357.0
PYH1_k127_5347532_1 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000002137 236.0
PYH1_k127_5347532_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 239.0
PYH1_k127_5347532_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000183 163.0
PYH1_k127_5347532_4 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000002258 149.0
PYH1_k127_5347532_5 phosphoribosyl-AMP cyclohydrolase activity K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000002232 145.0
PYH1_k127_5347532_6 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000001222 139.0
PYH1_k127_5347532_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000002103 138.0
PYH1_k127_5347532_8 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000002497 131.0
PYH1_k127_5371387_0 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005721 271.0
PYH1_k127_5371387_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000003227 166.0
PYH1_k127_5371521_0 Endopeptidase La K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 603.0
PYH1_k127_5371521_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
PYH1_k127_5371521_2 PFAM VWA domain containing CoxE-like protein K09989 - - 0.0000000000000000000000000000000000000001653 153.0
PYH1_k127_540657_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
PYH1_k127_540657_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000007015 151.0
PYH1_k127_540657_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000247 138.0
PYH1_k127_540657_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000001286 128.0
PYH1_k127_5437005_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 314.0
PYH1_k127_5437005_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004162 276.0
PYH1_k127_5437005_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001896 272.0
PYH1_k127_5486263_0 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 455.0
PYH1_k127_5486263_1 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007335 287.0
PYH1_k127_5486263_2 metallopeptidase activity K03933 - - 0.00000000000000000000000000000000000003011 166.0
PYH1_k127_5486263_3 methyltransferase - - - 0.000000000000000000000000006411 124.0
PYH1_k127_5486263_4 Right handed beta helix region - - - 0.00000002045 68.0
PYH1_k127_549734_0 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 340.0
PYH1_k127_549734_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002762 250.0
PYH1_k127_549734_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000003075 204.0
PYH1_k127_549734_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000004613 184.0
PYH1_k127_549734_4 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000001464 171.0
PYH1_k127_549734_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000099 85.0
PYH1_k127_549734_6 helix_turn_helix, mercury resistance - - - 0.000000000003529 68.0
PYH1_k127_5632584_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 516.0
PYH1_k127_5632584_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 472.0
PYH1_k127_5632584_10 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000527 274.0
PYH1_k127_5632584_11 Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 260.0
PYH1_k127_5632584_12 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000009953 243.0
PYH1_k127_5632584_13 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000006556 156.0
PYH1_k127_5632584_14 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000001527 117.0
PYH1_k127_5632584_15 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000004311 93.0
PYH1_k127_5632584_16 cell adhesion involved in biofilm formation - - - 0.0001337 53.0
PYH1_k127_5632584_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 386.0
PYH1_k127_5632584_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 366.0
PYH1_k127_5632584_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
PYH1_k127_5632584_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 352.0
PYH1_k127_5632584_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 359.0
PYH1_k127_5632584_7 4Fe-4S double cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
PYH1_k127_5632584_8 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 320.0
PYH1_k127_5632584_9 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
PYH1_k127_5675264_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 366.0
PYH1_k127_5675264_1 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 300.0
PYH1_k127_5675264_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000004721 87.0
PYH1_k127_569658_0 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000004697 111.0
PYH1_k127_569658_1 - - - - 0.00000000000004963 77.0
PYH1_k127_569658_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000003911 50.0
PYH1_k127_5719500_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 370.0
PYH1_k127_5719500_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 359.0
PYH1_k127_5719500_2 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001715 261.0
PYH1_k127_5719500_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001809 120.0
PYH1_k127_5721315_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000091 224.0
PYH1_k127_5721315_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000501 188.0
PYH1_k127_5721315_2 CoA-transferase family III K07544 - 2.8.3.15 0.000000000000000000000000000000000000000000002485 173.0
PYH1_k127_5721792_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 475.0
PYH1_k127_5721792_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000002804 144.0
PYH1_k127_5721792_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000001019 57.0
PYH1_k127_5793465_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 7.979e-282 878.0
PYH1_k127_5793465_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.413e-194 618.0
PYH1_k127_5793465_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000001099 168.0
PYH1_k127_5793465_11 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000004969 136.0
PYH1_k127_5793465_12 - - - - 0.0000000000000000000000000000003688 124.0
PYH1_k127_5793465_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000001114 124.0
PYH1_k127_5793465_14 methyltransferase - - - 0.000000000000000000000000008912 113.0
PYH1_k127_5793465_15 - - - - 0.000000000000000000117 88.0
PYH1_k127_5793465_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 537.0
PYH1_k127_5793465_3 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 334.0
PYH1_k127_5793465_4 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 317.0
PYH1_k127_5793465_5 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
PYH1_k127_5793465_6 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001577 270.0
PYH1_k127_5793465_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000003869 223.0
PYH1_k127_5793465_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001647 201.0
PYH1_k127_5793465_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000001847 181.0
PYH1_k127_579905_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 459.0
PYH1_k127_579905_1 Best Blastp hit gi 10176666 dbj BAB07760.1 (AP001520) BH4041 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003897 247.0
PYH1_k127_579905_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001399 168.0
PYH1_k127_579905_3 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000000004228 145.0
PYH1_k127_579905_4 PFAM Integrase catalytic region K07497 - - 0.0000000000006844 68.0
PYH1_k127_579905_5 Transposase IS116 IS110 IS902 family protein - - - 0.000000000003538 66.0
PYH1_k127_579905_6 EamA-like transporter family - - - 0.0000000000216 74.0
PYH1_k127_5874982_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000008562 239.0
PYH1_k127_5874982_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000003946 212.0
PYH1_k127_5874982_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000001926 204.0
PYH1_k127_5874982_3 PFAM B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000001547 196.0
PYH1_k127_5875736_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 294.0
PYH1_k127_5875736_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000001288 177.0
PYH1_k127_5875736_3 KR domain - - - 0.000000000000000000000000000000003602 139.0
PYH1_k127_5875736_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000034 116.0
PYH1_k127_5875736_5 TAP-like protein - - - 0.0000000000000000000000000003634 124.0
PYH1_k127_5892179_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 494.0
PYH1_k127_5902314_0 Hydantoinase/oxoprolinase N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 563.0
PYH1_k127_5902314_1 acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000001422 214.0
PYH1_k127_5902314_2 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000003653 203.0
PYH1_k127_5902314_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000002156 188.0
PYH1_k127_5902314_4 Forkhead associated domain - - - 0.000000000000000000003725 102.0
PYH1_k127_5902314_5 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000003478 89.0
PYH1_k127_5912211_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 3.134e-314 993.0
PYH1_k127_5912211_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.618e-218 685.0
PYH1_k127_5912211_2 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.967e-210 666.0
PYH1_k127_5912211_3 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 364.0
PYH1_k127_5912211_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 326.0
PYH1_k127_5912211_5 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 308.0
PYH1_k127_5912211_6 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
PYH1_k127_5912211_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
PYH1_k127_5912211_8 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003137 168.0
PYH1_k127_5912211_9 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000001503 126.0
PYH1_k127_5963741_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 531.0
PYH1_k127_5963741_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
PYH1_k127_5963741_10 Protein of unknown function (DUF664) - - - 0.000000000000000001499 92.0
PYH1_k127_5963741_11 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000004897 83.0
PYH1_k127_5963741_12 Major Facilitator Superfamily - - - 0.0000000000005683 81.0
PYH1_k127_5963741_13 Phospholipase_D-nuclease N-terminal - - - 0.0001959 44.0
PYH1_k127_5963741_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 356.0
PYH1_k127_5963741_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 307.0
PYH1_k127_5963741_4 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 301.0
PYH1_k127_5963741_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000001029 201.0
PYH1_k127_5963741_6 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000002129 148.0
PYH1_k127_5963741_7 FMN-dependent dehydrogenase K00459 - 1.13.12.16 0.00000000000000000000000000000000001905 147.0
PYH1_k127_5963741_8 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000003184 108.0
PYH1_k127_5963741_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000001072 96.0
PYH1_k127_6006082_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 8.968e-295 922.0
PYH1_k127_6006082_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 524.0
PYH1_k127_6006082_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 512.0
PYH1_k127_6006082_3 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
PYH1_k127_6006082_4 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003417 252.0
PYH1_k127_6006082_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000003409 166.0
PYH1_k127_6006082_6 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00001161 55.0
PYH1_k127_6014852_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 593.0
PYH1_k127_6014852_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 449.0
PYH1_k127_6014852_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 353.0
PYH1_k127_6014852_3 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007185 297.0
PYH1_k127_6014852_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002952 230.0
PYH1_k127_6014852_5 Response regulator receiver domain K02658 - - 0.0000006942 58.0
PYH1_k127_6034001_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 377.0
PYH1_k127_6034001_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000003257 200.0
PYH1_k127_6034001_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000001767 193.0
PYH1_k127_6034001_3 MaoC like domain - - - 0.00000000000000000000000000000000000006599 146.0
PYH1_k127_6034001_4 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000286 116.0
PYH1_k127_6034001_5 ABC-2 type transporter K01992 - - 0.000000008057 58.0
PYH1_k127_6034939_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 358.0
PYH1_k127_6034939_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 289.0
PYH1_k127_6034939_2 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000004749 136.0
PYH1_k127_6034939_3 xylan catabolic process K03932 - - 0.00000000000000001866 93.0
PYH1_k127_6034939_4 dehydratase - - - 0.000002125 55.0
PYH1_k127_6042013_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 4.417e-208 672.0
PYH1_k127_6042013_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 589.0
PYH1_k127_6042013_10 Thiamine-binding protein - - - 0.0000000000000000000000007377 106.0
PYH1_k127_6042013_11 COG0346 Lactoylglutathione lyase and related lyases K05606,K07588 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.000000000001769 74.0
PYH1_k127_6042013_2 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
PYH1_k127_6042013_3 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 349.0
PYH1_k127_6042013_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 312.0
PYH1_k127_6042013_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 287.0
PYH1_k127_6042013_6 ABC-type nitrate sulfonate bicarbonate transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000186 232.0
PYH1_k127_6042013_7 - - - - 0.0000000000000000000000000000000000000000000000000000007888 203.0
PYH1_k127_6042013_8 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.0000000000000000000000000000000003678 139.0
PYH1_k127_6042013_9 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000000000001689 127.0
PYH1_k127_6055178_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.99e-212 672.0
PYH1_k127_6055178_1 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 543.0
PYH1_k127_6055178_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 390.0
PYH1_k127_6055178_3 lysyltransferase activity K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 319.0
PYH1_k127_6055178_4 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 304.0
PYH1_k127_6055178_5 Amidohydrolase family - - - 0.000000000000006419 78.0
PYH1_k127_6055178_6 Uncharacterised conserved protein (DUF2156) - - - 0.000000004097 66.0
PYH1_k127_6055178_7 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.00000001348 57.0
PYH1_k127_6055283_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 369.0
PYH1_k127_6066422_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1239.0
PYH1_k127_6066422_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.158e-308 956.0
PYH1_k127_6066422_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000226 141.0
PYH1_k127_6066422_11 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000001811 87.0
PYH1_k127_6066422_12 PFAM Cyclic nucleotide-binding domain - - - 0.000000000000007939 81.0
PYH1_k127_6066422_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000007772 71.0
PYH1_k127_6066422_2 HMGL-like K02594 - 2.3.3.14 1.44e-202 639.0
PYH1_k127_6066422_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 589.0
PYH1_k127_6066422_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
PYH1_k127_6066422_5 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH1_k127_6066422_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000007654 252.0
PYH1_k127_6066422_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
PYH1_k127_6066422_8 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001164 249.0
PYH1_k127_6066422_9 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000000000000000000007938 175.0
PYH1_k127_6068387_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 535.0
PYH1_k127_6068387_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 339.0
PYH1_k127_6068387_2 Nitroreductase family K19285 - 1.5.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000008821 259.0
PYH1_k127_6088297_0 efflux protein, MATE family - - - 0.00000000000000000000000000000000000000000007592 175.0
PYH1_k127_6134814_0 PFAM multicopper oxidase type 2 - - - 7.866e-311 964.0
PYH1_k127_6134814_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000001363 199.0
PYH1_k127_6134814_2 Outer membrane receptor - - - 0.0003803 51.0
PYH1_k127_6240305_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1043.0
PYH1_k127_6240305_1 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 400.0
PYH1_k127_6240305_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
PYH1_k127_6240305_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000006908 72.0
PYH1_k127_6240305_4 Regulatory protein, FmdB family - - - 0.0000000005658 64.0
PYH1_k127_6240305_5 TIGRFAM hydrolase CocE NonD family protein K06978 - - 0.00000003183 56.0
PYH1_k127_6240305_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000002285 57.0
PYH1_k127_6242769_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000004849 220.0
PYH1_k127_6242769_1 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000002122 164.0
PYH1_k127_6242769_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000007564 86.0
PYH1_k127_6242769_4 metallocarboxypeptidase activity K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.000000000000006383 88.0
PYH1_k127_6256274_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 278.0
PYH1_k127_6256274_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000002015 115.0
PYH1_k127_6256274_2 Ferritin-like domain - - - 0.000000000000004659 87.0
PYH1_k127_6256274_3 Lamin Tail Domain K07004 - - 0.0000003634 62.0
PYH1_k127_6257287_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1107.0
PYH1_k127_6257287_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 5e-324 1019.0
PYH1_k127_6257287_10 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000006597 279.0
PYH1_k127_6257287_11 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001693 275.0
PYH1_k127_6257287_12 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000002464 244.0
PYH1_k127_6257287_13 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000008251 193.0
PYH1_k127_6257287_14 - - - - 0.0000000000000000000000000000000000000000000000002129 184.0
PYH1_k127_6257287_15 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000005781 156.0
PYH1_k127_6257287_16 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000007638 136.0
PYH1_k127_6257287_17 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000808 138.0
PYH1_k127_6257287_18 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates - - - 0.00000000000000000000000000000003097 130.0
PYH1_k127_6257287_19 - - - - 0.00000000000000000000000000005702 117.0
PYH1_k127_6257287_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 608.0
PYH1_k127_6257287_20 - - - - 0.000000000000000000000123 98.0
PYH1_k127_6257287_21 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000005337 96.0
PYH1_k127_6257287_22 Glutamine amidotransferase class-I - - - 0.0000000000000000000005569 99.0
PYH1_k127_6257287_23 - - - - 0.000000000000000001787 87.0
PYH1_k127_6257287_25 GIY-YIG catalytic domain K07461 - - 0.00000000000000002447 83.0
PYH1_k127_6257287_26 DNA polymerase X family K02347 - - 0.00000000000007882 76.0
PYH1_k127_6257287_27 - - - - 0.0000000003595 61.0
PYH1_k127_6257287_28 - - - - 0.000000007808 61.0
PYH1_k127_6257287_3 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 593.0
PYH1_k127_6257287_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 529.0
PYH1_k127_6257287_5 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 469.0
PYH1_k127_6257287_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 457.0
PYH1_k127_6257287_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
PYH1_k127_6257287_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 311.0
PYH1_k127_6257287_9 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 308.0
PYH1_k127_6276820_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 604.0
PYH1_k127_6276820_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 518.0
PYH1_k127_6276820_10 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000001371 132.0
PYH1_k127_6276820_11 AAA domain K07028 - - 0.00000000000392 75.0
PYH1_k127_6276820_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 516.0
PYH1_k127_6276820_3 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 374.0
PYH1_k127_6276820_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 339.0
PYH1_k127_6276820_5 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 253.0
PYH1_k127_6276820_6 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000007846 234.0
PYH1_k127_6276820_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000001513 153.0
PYH1_k127_6276820_8 PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000001868 160.0
PYH1_k127_6276820_9 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000189 149.0
PYH1_k127_6308866_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 1.995e-202 634.0
PYH1_k127_6308866_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 590.0
PYH1_k127_6308866_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 264.0
PYH1_k127_6308866_3 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000005158 213.0
PYH1_k127_6314200_1 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000005452 183.0
PYH1_k127_6314200_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002778 52.0
PYH1_k127_6330575_0 Dak1_2 K07030 - - 2.048e-209 663.0
PYH1_k127_6330575_1 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 289.0
PYH1_k127_6330575_2 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 276.0
PYH1_k127_6330575_3 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003199 264.0
PYH1_k127_6330575_4 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.0000000000000000000000001319 109.0
PYH1_k127_6330575_5 Ribosomal L28 family K02902 - - 0.0000000000000000000003197 97.0
PYH1_k127_6381843_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 422.0
PYH1_k127_6381843_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
PYH1_k127_6381843_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 329.0
PYH1_k127_6381843_3 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH1_k127_6410876_0 Tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 598.0
PYH1_k127_6410876_1 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 430.0
PYH1_k127_6410876_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000003126 217.0
PYH1_k127_6410876_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000009647 166.0
PYH1_k127_6410876_4 - - - - 0.000000000000000000000000000000000000000002596 158.0
PYH1_k127_6410876_5 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000004779 148.0
PYH1_k127_6410876_6 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000001631 134.0
PYH1_k127_6410876_7 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000004316 121.0
PYH1_k127_6410876_8 - - - - 0.000000000008022 70.0
PYH1_k127_6410876_9 PAAR repeat-containing protein - - - 0.00000001488 56.0
PYH1_k127_641554_0 Poly A polymerase head domain K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 309.0
PYH1_k127_641554_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 297.0
PYH1_k127_641554_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
PYH1_k127_641554_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000001348 187.0
PYH1_k127_641554_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000004062 83.0
PYH1_k127_6441883_0 serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000001901 199.0
PYH1_k127_6441883_1 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000299 174.0
PYH1_k127_6441883_2 FHA domain protein - - - 0.00005146 53.0
PYH1_k127_6449914_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000002682 228.0
PYH1_k127_6449914_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000009559 208.0
PYH1_k127_6449914_2 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000004512 155.0
PYH1_k127_6449914_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00004389 46.0
PYH1_k127_6462289_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000875 242.0
PYH1_k127_6462289_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000006658 216.0
PYH1_k127_6462289_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000008439 175.0
PYH1_k127_6462289_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000002051 173.0
PYH1_k127_6462289_4 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000004999 151.0
PYH1_k127_6462289_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000002298 158.0
PYH1_k127_6473844_0 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
PYH1_k127_6473844_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 302.0
PYH1_k127_6473844_2 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000005077 138.0
PYH1_k127_6473844_3 PFAM Rubrerythrin - - - 0.000000000000000000000000000002733 126.0
PYH1_k127_657891_0 AMP-binding enzyme C-terminal domain - - - 6.041e-213 672.0
PYH1_k127_657891_1 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 441.0
PYH1_k127_657891_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002111 238.0
PYH1_k127_657891_3 GYD domain - - - 0.000000000000000000000000000002201 124.0
PYH1_k127_657891_4 - - - - 0.000000001443 68.0
PYH1_k127_6600013_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 451.0
PYH1_k127_6600013_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 419.0
PYH1_k127_6600013_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 370.0
PYH1_k127_6600013_3 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 320.0
PYH1_k127_6600013_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000004333 218.0
PYH1_k127_6600013_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000461 117.0
PYH1_k127_6600013_6 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000005026 72.0
PYH1_k127_6613344_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001715 259.0
PYH1_k127_6613344_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002852 259.0
PYH1_k127_6613344_2 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.0000000009862 64.0
PYH1_k127_6613344_3 - - - - 0.000001043 57.0
PYH1_k127_6625661_0 Bacterial dnaA protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 478.0
PYH1_k127_6625661_1 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
PYH1_k127_6625661_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000001815 100.0
PYH1_k127_6625661_3 Methyltransferase type 11 - - - 0.00000000000000000001047 102.0
PYH1_k127_6689675_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 406.0
PYH1_k127_6689675_1 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 357.0
PYH1_k127_6689675_2 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
PYH1_k127_6689675_3 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000009198 112.0
PYH1_k127_6689675_4 Hydrolase, TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000001297 89.0
PYH1_k127_6689675_5 DUF167 K09131 - - 0.000000000000004477 78.0
PYH1_k127_6720579_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.342e-311 977.0
PYH1_k127_6720579_1 electron transfer activity K03615 - - 0.000000000000000000000000000000000000000000000000003836 184.0
PYH1_k127_6720579_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000005414 102.0
PYH1_k127_6720579_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000001277 84.0
PYH1_k127_6757285_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 466.0
PYH1_k127_6757285_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000006527 69.0
PYH1_k127_6770008_0 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 490.0
PYH1_k127_6770008_1 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000002772 187.0
PYH1_k127_6770008_2 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000245 85.0
PYH1_k127_6792770_0 nitronate monooxygenase activity K00088,K00459 - 1.1.1.205,1.13.12.16 3.479e-293 905.0
PYH1_k127_6792770_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 5.461e-222 700.0
PYH1_k127_6792770_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000838 145.0
PYH1_k127_6792770_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000004062 80.0
PYH1_k127_6792770_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.499e-195 624.0
PYH1_k127_6792770_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 406.0
PYH1_k127_6792770_4 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 356.0
PYH1_k127_6792770_5 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 342.0
PYH1_k127_6792770_6 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 327.0
PYH1_k127_6792770_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000002691 205.0
PYH1_k127_6792770_8 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000002224 189.0
PYH1_k127_6792770_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000001482 173.0
PYH1_k127_6811002_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 576.0
PYH1_k127_6811002_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 334.0
PYH1_k127_6811002_10 PFAM glutaredoxin - - - 0.00000000000000000000000001748 113.0
PYH1_k127_6811002_11 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000002366 109.0
PYH1_k127_6811002_12 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000173 66.0
PYH1_k127_6811002_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
PYH1_k127_6811002_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005713 230.0
PYH1_k127_6811002_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002609 214.0
PYH1_k127_6811002_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000003914 190.0
PYH1_k127_6811002_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000002823 148.0
PYH1_k127_6811002_7 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000002596 133.0
PYH1_k127_6811002_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000009643 120.0
PYH1_k127_6811002_9 - - - - 0.0000000000000000000000000002375 125.0
PYH1_k127_6834004_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 559.0
PYH1_k127_6834004_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 556.0
PYH1_k127_6834004_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
PYH1_k127_6834004_11 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002046 247.0
PYH1_k127_6834004_12 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001709 254.0
PYH1_k127_6834004_13 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
PYH1_k127_6834004_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
PYH1_k127_6834004_15 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000001482 219.0
PYH1_k127_6834004_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
PYH1_k127_6834004_17 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000138 198.0
PYH1_k127_6834004_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000636 195.0
PYH1_k127_6834004_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000007936 189.0
PYH1_k127_6834004_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 541.0
PYH1_k127_6834004_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000003643 179.0
PYH1_k127_6834004_21 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000005207 175.0
PYH1_k127_6834004_22 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000003612 170.0
PYH1_k127_6834004_23 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000004908 170.0
PYH1_k127_6834004_24 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000003026 165.0
PYH1_k127_6834004_25 Dihydroxyacetone kinase family - - - 0.0000000000000000000000000000000000000000001014 171.0
PYH1_k127_6834004_26 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002994 161.0
PYH1_k127_6834004_27 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000002216 160.0
PYH1_k127_6834004_28 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000002744 160.0
PYH1_k127_6834004_29 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000003137 166.0
PYH1_k127_6834004_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 420.0
PYH1_k127_6834004_30 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000007113 155.0
PYH1_k127_6834004_31 structural constituent of ribosome K02879 - - 0.00000000000000000000000000000000000000002705 154.0
PYH1_k127_6834004_32 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001504 147.0
PYH1_k127_6834004_33 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000001626 137.0
PYH1_k127_6834004_34 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000009395 134.0
PYH1_k127_6834004_35 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000002183 127.0
PYH1_k127_6834004_36 Ribosomal protein S16 K02959 - - 0.000000000000000000000000000003628 121.0
PYH1_k127_6834004_37 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000004259 113.0
PYH1_k127_6834004_38 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000001893 111.0
PYH1_k127_6834004_39 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001181 107.0
PYH1_k127_6834004_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 365.0
PYH1_k127_6834004_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000003057 103.0
PYH1_k127_6834004_41 KH domain K06960 - - 0.0000000000000000000000551 102.0
PYH1_k127_6834004_42 - - - - 0.000000000000000000002686 100.0
PYH1_k127_6834004_43 Phosphoesterase K07095 - - 0.00000000000000000004191 96.0
PYH1_k127_6834004_44 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002443 87.0
PYH1_k127_6834004_45 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009374 68.0
PYH1_k127_6834004_46 structural constituent of ribosome K02904 - - 0.00000000008804 64.0
PYH1_k127_6834004_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
PYH1_k127_6834004_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 302.0
PYH1_k127_6834004_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 283.0
PYH1_k127_6834004_8 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
PYH1_k127_6834004_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001577 254.0
PYH1_k127_6834532_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 2.06e-209 676.0
PYH1_k127_6834532_1 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 2.973e-209 675.0
PYH1_k127_6834532_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000004893 214.0
PYH1_k127_6834532_3 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K00008 - 1.1.1.14 0.0000000000000000000000000000000005927 145.0
PYH1_k127_6834532_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001101 82.0
PYH1_k127_6841748_0 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 588.0
PYH1_k127_6841748_1 ABC transporter, transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 507.0
PYH1_k127_6841748_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000002611 193.0
PYH1_k127_6841748_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000004038 126.0
PYH1_k127_6872075_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.574e-195 619.0
PYH1_k127_6872075_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 550.0
PYH1_k127_6872075_10 TetR family transcriptional regulator - - - 0.000000000000000000000000003711 119.0
PYH1_k127_6872075_11 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000001465 108.0
PYH1_k127_6872075_12 Preprotein translocase SecG subunit K03075 - - 0.000000000000000006533 87.0
PYH1_k127_6872075_13 membrane - - - 0.0000000001837 65.0
PYH1_k127_6872075_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 351.0
PYH1_k127_6872075_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH1_k127_6872075_4 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 309.0
PYH1_k127_6872075_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
PYH1_k127_6872075_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
PYH1_k127_6872075_7 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000002874 249.0
PYH1_k127_6872075_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000007986 159.0
PYH1_k127_6880188_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 520.0
PYH1_k127_6880188_1 malic enzyme K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 448.0
PYH1_k127_6880188_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 372.0
PYH1_k127_6880188_3 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 372.0
PYH1_k127_6880188_4 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 341.0
PYH1_k127_6880188_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
PYH1_k127_6880188_6 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000004265 193.0
PYH1_k127_6880188_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004462 169.0
PYH1_k127_6880188_8 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000007661 151.0
PYH1_k127_6880188_9 Ecdysteroid kinase - - - 0.0000001432 56.0
PYH1_k127_6882598_0 phosphatidylinositol metabolic process K13671 - - 0.0000000000000000000000000000000000000000000000004501 193.0
PYH1_k127_6882598_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000009331 127.0
PYH1_k127_6882598_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000002035 115.0
PYH1_k127_6882598_3 Helix-turn-helix domain - - - 0.0000000106 61.0
PYH1_k127_6882598_4 - - - - 0.0000004804 57.0
PYH1_k127_6913603_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
PYH1_k127_6913603_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 322.0
PYH1_k127_6913603_2 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 322.0
PYH1_k127_6913603_3 GntR family - - - 0.000000002064 64.0
PYH1_k127_6913603_4 Carboxylesterase family K03929 - - 0.000003052 51.0
PYH1_k127_6913603_5 Acetyltransferase (GNAT) domain - - - 0.000009185 54.0
PYH1_k127_6934724_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 558.0
PYH1_k127_6934724_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 518.0
PYH1_k127_6934724_10 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000001223 205.0
PYH1_k127_6934724_11 Cupin domain protein - - - 0.0000000000000000000000000000000000000001626 152.0
PYH1_k127_6934724_12 - - - - 0.0000000000000000000000000000421 118.0
PYH1_k127_6934724_13 NifU-like domain - - - 0.00000000000000000000000006428 108.0
PYH1_k127_6934724_14 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000008267 111.0
PYH1_k127_6934724_15 CoA-transferase family III K08298 - 2.8.3.21 0.0009593 44.0
PYH1_k127_6934724_2 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 455.0
PYH1_k127_6934724_3 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 462.0
PYH1_k127_6934724_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 398.0
PYH1_k127_6934724_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 392.0
PYH1_k127_6934724_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 280.0
PYH1_k127_6934724_7 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH1_k127_6934724_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
PYH1_k127_6934724_9 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
PYH1_k127_6971026_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
PYH1_k127_6971026_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 349.0
PYH1_k127_6971026_10 - - - - 0.000000000000000000000000000000000001657 147.0
PYH1_k127_6971026_12 Belongs to the 'phage' integrase family K04763 - - 0.00008333 51.0
PYH1_k127_6971026_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
PYH1_k127_6971026_3 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 276.0
PYH1_k127_6971026_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 260.0
PYH1_k127_6971026_5 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000002952 246.0
PYH1_k127_6971026_6 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001956 246.0
PYH1_k127_6971026_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000001579 211.0
PYH1_k127_6971026_8 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000001177 193.0
PYH1_k127_6971026_9 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000003197 158.0
PYH1_k127_6998073_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.195e-259 817.0
PYH1_k127_6998073_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.831e-233 734.0
PYH1_k127_6998073_10 nitrite transmembrane transporter activity K02575,K08223 - - 0.00000000000003522 85.0
PYH1_k127_6998073_11 - - - - 0.00003186 46.0
PYH1_k127_6998073_2 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 418.0
PYH1_k127_6998073_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
PYH1_k127_6998073_4 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 339.0
PYH1_k127_6998073_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 323.0
PYH1_k127_6998073_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 326.0
PYH1_k127_6998073_7 Formyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001178 285.0
PYH1_k127_6998073_8 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
PYH1_k127_7022056_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1170.0
PYH1_k127_7022056_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.154e-201 642.0
PYH1_k127_7022056_10 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004317 263.0
PYH1_k127_7022056_11 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001356 256.0
PYH1_k127_7022056_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007483 258.0
PYH1_k127_7022056_13 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001424 247.0
PYH1_k127_7022056_14 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000001156 224.0
PYH1_k127_7022056_15 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000002104 213.0
PYH1_k127_7022056_16 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000001791 218.0
PYH1_k127_7022056_17 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000008376 199.0
PYH1_k127_7022056_18 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000005347 189.0
PYH1_k127_7022056_19 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000009682 187.0
PYH1_k127_7022056_2 chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 538.0
PYH1_k127_7022056_20 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000009493 170.0
PYH1_k127_7022056_21 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000102 173.0
PYH1_k127_7022056_22 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000009535 173.0
PYH1_k127_7022056_23 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000009521 151.0
PYH1_k127_7022056_24 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000004251 140.0
PYH1_k127_7022056_25 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000208 151.0
PYH1_k127_7022056_27 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000001105 118.0
PYH1_k127_7022056_28 Serine aminopeptidase, S33 - - - 0.000000000000000000000000006299 121.0
PYH1_k127_7022056_29 PFAM SpoVT AbrB domain protein K07172 - - 0.000000000000000000000000008245 115.0
PYH1_k127_7022056_3 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 499.0
PYH1_k127_7022056_30 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000008757 102.0
PYH1_k127_7022056_31 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000004142 93.0
PYH1_k127_7022056_32 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000004824 86.0
PYH1_k127_7022056_33 - - - - 0.000000000000000521 88.0
PYH1_k127_7022056_34 PFAM glycine cleavage H-protein - - - 0.0000000000001075 79.0
PYH1_k127_7022056_35 cellular response to starvation - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000415 70.0
PYH1_k127_7022056_36 - - - - 0.000002199 53.0
PYH1_k127_7022056_37 - - - - 0.0004646 47.0
PYH1_k127_7022056_4 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 369.0
PYH1_k127_7022056_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 347.0
PYH1_k127_7022056_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 351.0
PYH1_k127_7022056_7 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 286.0
PYH1_k127_7022056_8 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006876 278.0
PYH1_k127_7022056_9 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002081 261.0
PYH1_k127_7033378_0 5'-nucleotidase, C-terminal domain K01081,K07004,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000002648 209.0
PYH1_k127_7033378_1 TM2 domain - - - 0.00000001338 64.0
PYH1_k127_7038681_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 428.0
PYH1_k127_7038681_1 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 302.0
PYH1_k127_7038681_10 Helix-turn-helix domain - - - 0.000000000000004511 78.0
PYH1_k127_7038681_12 Domain of unknown function (DUF362) - - - 0.00000000002985 66.0
PYH1_k127_7038681_13 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000001018 69.0
PYH1_k127_7038681_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007135 282.0
PYH1_k127_7038681_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009868 240.0
PYH1_k127_7038681_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000004162 229.0
PYH1_k127_7038681_5 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
PYH1_k127_7038681_6 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000000002181 205.0
PYH1_k127_7038681_7 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000000486 143.0
PYH1_k127_7038681_8 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000002757 132.0
PYH1_k127_7038681_9 - - - - 0.0000000000000000008805 96.0
PYH1_k127_7046375_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.457e-299 932.0
PYH1_k127_7046375_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.288e-294 919.0
PYH1_k127_7046375_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 541.0
PYH1_k127_7046375_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000004429 177.0
PYH1_k127_7046375_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000151 172.0
PYH1_k127_7046375_5 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000003916 168.0
PYH1_k127_7046375_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000003624 133.0
PYH1_k127_7046375_7 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001244 80.0
PYH1_k127_7046375_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00003292 49.0
PYH1_k127_7059835_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 428.0
PYH1_k127_7059835_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 378.0
PYH1_k127_7059835_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000006268 232.0
PYH1_k127_7059835_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000005513 179.0
PYH1_k127_7059835_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000008918 101.0
PYH1_k127_7155739_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.601e-215 678.0
PYH1_k127_7155739_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.485e-197 626.0
PYH1_k127_7155739_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000004301 167.0
PYH1_k127_7155739_11 AMP binding - - - 0.0000000000000000000000000000003538 128.0
PYH1_k127_7155739_12 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000001374 122.0
PYH1_k127_7155739_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000001737 108.0
PYH1_k127_7155739_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000004278 98.0
PYH1_k127_7155739_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 537.0
PYH1_k127_7155739_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 523.0
PYH1_k127_7155739_4 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 518.0
PYH1_k127_7155739_5 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
PYH1_k127_7155739_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 444.0
PYH1_k127_7155739_7 PFAM Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002903 243.0
PYH1_k127_7155739_8 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
PYH1_k127_7155739_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000009395 213.0
PYH1_k127_7167815_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.523e-294 931.0
PYH1_k127_7167815_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 586.0
PYH1_k127_7167815_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000004381 251.0
PYH1_k127_7167815_11 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006364 231.0
PYH1_k127_7167815_12 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000003035 207.0
PYH1_k127_7167815_13 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000004762 199.0
PYH1_k127_7167815_14 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000006816 179.0
PYH1_k127_7167815_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001284 174.0
PYH1_k127_7167815_16 3-hydroxyacyl-CoA dehydrogenase K00074,K15016,K15019 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17 0.000000000000000000000000000000000000000001046 166.0
PYH1_k127_7167815_17 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000006047 146.0
PYH1_k127_7167815_18 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000005485 115.0
PYH1_k127_7167815_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 484.0
PYH1_k127_7167815_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 441.0
PYH1_k127_7167815_4 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 346.0
PYH1_k127_7167815_5 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
PYH1_k127_7167815_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 310.0
PYH1_k127_7167815_7 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 306.0
PYH1_k127_7167815_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001521 282.0
PYH1_k127_7167815_9 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007261 280.0
PYH1_k127_7186140_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000007674 247.0
PYH1_k127_7186140_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
PYH1_k127_7186140_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K03340 - 1.4.1.16 0.00000000000000000000000000000000000000000000000000000001 202.0
PYH1_k127_7186140_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000000189 147.0
PYH1_k127_7186140_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K11329 - - 0.0000000000000000000001362 101.0
PYH1_k127_7190783_0 SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 312.0
PYH1_k127_7190783_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000007467 229.0
PYH1_k127_7190783_2 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000001211 217.0
PYH1_k127_7190783_3 Universal stress protein family - - - 0.00000000000000004155 89.0
PYH1_k127_7196128_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 555.0
PYH1_k127_7196128_1 Phage capsid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 488.0
PYH1_k127_7196128_2 Phage portal protein, SPP1 Gp6-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 296.0
PYH1_k127_7196128_3 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000003291 208.0
PYH1_k127_7196128_4 - - - - 0.000000000000000000000000000000000000000000000002421 180.0
PYH1_k127_7196128_5 - - - - 0.00000000000000000000000000000000009574 134.0
PYH1_k127_7196128_7 - - - - 0.0000000000006311 71.0
PYH1_k127_7196128_8 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000001687 67.0
PYH1_k127_7273679_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005729 225.0
PYH1_k127_7273679_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000005226 184.0
PYH1_k127_7273679_2 Acyltransferase family K11941 - - 0.00000000000000000000000000000000000934 152.0
PYH1_k127_7273679_3 - - - - 0.0008381 44.0
PYH1_k127_7317184_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.102e-241 754.0
PYH1_k127_7317184_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.949e-237 740.0
PYH1_k127_7317184_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000002508 98.0
PYH1_k127_7317184_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000000001454 79.0
PYH1_k127_7317184_12 - - - - 0.000000002929 63.0
PYH1_k127_7317184_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 385.0
PYH1_k127_7317184_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
PYH1_k127_7317184_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
PYH1_k127_7317184_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000003041 189.0
PYH1_k127_7317184_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000002358 164.0
PYH1_k127_7317184_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000004143 162.0
PYH1_k127_7317184_8 Zincin-like metallopeptidase - - - 0.00000000000000000000000000001565 121.0
PYH1_k127_7317184_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000007069 119.0
PYH1_k127_7352538_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000001329 149.0
PYH1_k127_7404260_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
PYH1_k127_7404260_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 299.0
PYH1_k127_7404260_2 PAC2 family K07159 - - 0.00000000000000000000001812 102.0
PYH1_k127_7404260_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000008532 93.0
PYH1_k127_7404260_4 membrane - - - 0.000000008308 66.0
PYH1_k127_7423810_0 Domain of unknown function (DUF1998) K06877 - - 1.725e-295 925.0
PYH1_k127_7423810_1 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000001668 188.0
PYH1_k127_7423810_2 Protein conserved in bacteria K09764 - - 0.00000000000000000005004 92.0
PYH1_k127_7423810_3 Helix-turn-helix - - - 0.000000000000000000509 88.0
PYH1_k127_7470364_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 9.07e-219 683.0
PYH1_k127_7470364_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 488.0
PYH1_k127_7470364_10 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000005091 136.0
PYH1_k127_7470364_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002066 82.0
PYH1_k127_7470364_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000001191 70.0
PYH1_k127_7470364_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 466.0
PYH1_k127_7470364_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 425.0
PYH1_k127_7470364_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 332.0
PYH1_k127_7470364_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000546 267.0
PYH1_k127_7470364_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006501 254.0
PYH1_k127_7470364_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
PYH1_k127_7470364_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
PYH1_k127_7470364_9 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000002594 179.0
PYH1_k127_7482409_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 353.0
PYH1_k127_7482409_1 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
PYH1_k127_7482409_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 305.0
PYH1_k127_7482409_3 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 291.0
PYH1_k127_7482409_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 292.0
PYH1_k127_7482409_5 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000001142 253.0
PYH1_k127_7482409_6 Electron transfer flavoprotein domain K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000009684 175.0
PYH1_k127_7482409_7 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000004578 145.0
PYH1_k127_7482409_8 Rhodanese Homology Domain - - - 0.000000000000000000000000000000003941 133.0
PYH1_k127_7482409_9 Protein of unknown function (DUF664) - - - 0.00000000000002057 80.0
PYH1_k127_7522597_0 ABC transporter K06158 - - 4.275e-208 667.0
PYH1_k127_7522597_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004533 238.0
PYH1_k127_7522597_2 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH1_k127_7522597_3 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000006515 175.0
PYH1_k127_7522597_4 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000005841 165.0
PYH1_k127_7522597_5 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.000000000000000000000000000003719 136.0
PYH1_k127_7637281_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 294.0
PYH1_k127_7637281_1 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000296 173.0
PYH1_k127_7637281_2 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000003764 127.0
PYH1_k127_7637281_3 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000004314 128.0
PYH1_k127_7637281_4 - - - - 0.0000000000000000003187 87.0
PYH1_k127_7637281_5 carotenoid biosynthetic process K10212 - - 0.0000000000007863 71.0
PYH1_k127_7637281_6 arsenate reductase (glutaredoxin) activity K05521 - 3.2.2.24 0.0000000004722 64.0
PYH1_k127_7639093_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 532.0
PYH1_k127_7639093_1 PFAM GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000001762 176.0
PYH1_k127_7639093_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000001028 176.0
PYH1_k127_7639093_3 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000005469 166.0
PYH1_k127_7639093_4 PAAR repeat-containing protein - - - 0.000000000000000000000000000000000000007477 147.0
PYH1_k127_7639093_5 PFAM Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000005067 136.0
PYH1_k127_7639093_6 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000002717 138.0
PYH1_k127_7639093_7 cell adhesion involved in biofilm formation - - - 0.0000000000000000006949 101.0
PYH1_k127_7639093_8 Pkd domain containing protein - - - 0.00000000005356 76.0
PYH1_k127_7796872_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 455.0
PYH1_k127_7796872_1 Alpha-2-Macroglobulin K03910,K06530 GO:0000768,GO:0001932,GO:0001933,GO:0001942,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002576,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006949,GO:0006950,GO:0006952,GO:0007275,GO:0008150,GO:0008285,GO:0008544,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009653,GO:0009888,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0010837,GO:0010839,GO:0012505,GO:0012506,GO:0016020,GO:0016192,GO:0017015,GO:0019220,GO:0019222,GO:0019838,GO:0019955,GO:0022404,GO:0022405,GO:0023051,GO:0023057,GO:0030097,GO:0030099,GO:0030141,GO:0030154,GO:0030316,GO:0030512,GO:0030659,GO:0030667,GO:0030856,GO:0031090,GO:0031091,GO:0031092,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031410,GO:0031982,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032940,GO:0042127,GO:0042303,GO:0042325,GO:0042326,GO:0042633,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043588,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045595,GO:0045604,GO:0045616,GO:0045682,GO:0045936,GO:0046903,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050829,GO:0050830,GO:0050896,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051704,GO:0051707,GO:0060255,GO:0060429,GO:0061041,GO:0061045,GO:0065007,GO:0071944,GO:0072674,GO:0072675,GO:0080090,GO:0080134,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0097708,GO:0098542,GO:0098588,GO:0098773,GO:0098805,GO:0099503,GO:1903034,GO:1903035,GO:1903844,GO:1903845,GO:2000026 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 466.0
PYH1_k127_7796872_10 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
PYH1_k127_7796872_11 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000006537 237.0
PYH1_k127_7796872_12 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000001078 226.0
PYH1_k127_7796872_13 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000634 209.0
PYH1_k127_7796872_14 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000002342 213.0
PYH1_k127_7796872_15 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000001898 190.0
PYH1_k127_7796872_16 Belongs to the 2H phosphoesterase superfamily. YjcG family - - - 0.0000004802 60.0
PYH1_k127_7796872_17 - - - - 0.00005762 51.0
PYH1_k127_7796872_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 421.0
PYH1_k127_7796872_3 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 415.0
PYH1_k127_7796872_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 414.0
PYH1_k127_7796872_5 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 406.0
PYH1_k127_7796872_6 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 391.0
PYH1_k127_7796872_7 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 370.0
PYH1_k127_7796872_8 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 346.0
PYH1_k127_7796872_9 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 336.0
PYH1_k127_7821873_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003523 246.0
PYH1_k127_7821873_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000002353 231.0
PYH1_k127_7821873_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000004472 210.0
PYH1_k127_7867119_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266,K03388 - 1.4.1.13,1.4.1.14,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.651e-302 954.0
PYH1_k127_7867119_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.245e-259 832.0
PYH1_k127_7867119_10 Resolvase, N terminal domain - - - 0.000000000007863 65.0
PYH1_k127_7867119_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.775e-234 741.0
PYH1_k127_7867119_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 445.0
PYH1_k127_7867119_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 301.0
PYH1_k127_7867119_5 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
PYH1_k127_7867119_6 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000008022 203.0
PYH1_k127_7867119_7 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000005437 196.0
PYH1_k127_7867119_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000004606 188.0
PYH1_k127_7867119_9 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000007663 165.0
PYH1_k127_7886803_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 528.0
PYH1_k127_7886803_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 401.0
PYH1_k127_7886803_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 349.0
PYH1_k127_7886803_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000007404 218.0
PYH1_k127_7886803_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000004099 214.0
PYH1_k127_7886803_5 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000001358 177.0
PYH1_k127_7886803_6 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000001717 164.0
PYH1_k127_7916963_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 473.0
PYH1_k127_7916963_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000004155 241.0
PYH1_k127_7916963_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000001174 205.0
PYH1_k127_7916963_3 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000001564 190.0
PYH1_k127_7916963_4 R3H domain - - - 0.00000000000000000000000000000000000000004428 154.0
PYH1_k127_7921204_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 6.706e-304 949.0
PYH1_k127_7921204_1 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 381.0
PYH1_k127_7921204_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 342.0
PYH1_k127_7921204_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000001333 221.0
PYH1_k127_7921204_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000001768 146.0
PYH1_k127_7921204_5 4Fe-4S dicluster domain K00124,K07307 - - 0.00000000000000000000000000000006083 144.0
PYH1_k127_7958843_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.384e-233 737.0
PYH1_k127_7958843_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 443.0
PYH1_k127_7958843_10 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009284 274.0
PYH1_k127_7958843_11 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000874 265.0
PYH1_k127_7958843_12 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH1_k127_7958843_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
PYH1_k127_7958843_14 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000002177 223.0
PYH1_k127_7958843_15 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000001898 214.0
PYH1_k127_7958843_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000002062 180.0
PYH1_k127_7958843_17 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000002774 125.0
PYH1_k127_7958843_18 hydrogenase expression formation protein HypE K04655 - - 0.000000000000001118 76.0
PYH1_k127_7958843_2 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 424.0
PYH1_k127_7958843_20 - - - - 0.00009437 51.0
PYH1_k127_7958843_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 409.0
PYH1_k127_7958843_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 379.0
PYH1_k127_7958843_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 345.0
PYH1_k127_7958843_6 leucine import across plasma membrane K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 310.0
PYH1_k127_7958843_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 301.0
PYH1_k127_7958843_8 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 308.0
PYH1_k127_7958843_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 275.0
PYH1_k127_7976557_0 NAD synthase K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 567.0
PYH1_k127_7976557_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 349.0
PYH1_k127_7976557_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
PYH1_k127_7976557_3 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000002099 232.0
PYH1_k127_7977554_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 450.0
PYH1_k127_7977554_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 406.0
PYH1_k127_7977554_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH1_k127_8008224_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 564.0
PYH1_k127_8008224_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
PYH1_k127_8008224_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000008822 201.0
PYH1_k127_8008224_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000001015 206.0
PYH1_k127_8023533_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 382.0
PYH1_k127_8023533_1 nitrate reductase activity - - - 0.000000000000000000000000000000000009865 144.0
PYH1_k127_8023533_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000548 136.0
PYH1_k127_8023533_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000008682 98.0
PYH1_k127_8023533_4 - - - - 0.000000000000000004031 88.0
PYH1_k127_8023533_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000001597 78.0
PYH1_k127_8024247_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 466.0
PYH1_k127_8024247_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 337.0
PYH1_k127_8024247_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
PYH1_k127_8024247_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000001853 216.0
PYH1_k127_8024247_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000001229 206.0
PYH1_k127_8024247_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000003541 159.0
PYH1_k127_8024247_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000001797 77.0
PYH1_k127_803722_0 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 457.0
PYH1_k127_803722_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 338.0
PYH1_k127_803722_10 Transcriptional regulator - - - 0.0000000000000000000000000000113 127.0
PYH1_k127_803722_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 303.0
PYH1_k127_803722_3 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002429 214.0
PYH1_k127_803722_4 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000005961 226.0
PYH1_k127_803722_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000001692 193.0
PYH1_k127_803722_6 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000005756 184.0
PYH1_k127_803722_7 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.0000000000000000000000000000000000000000000000109 181.0
PYH1_k127_803722_8 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000007399 168.0
PYH1_k127_803722_9 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000001338 154.0
PYH1_k127_8046661_0 Transposase zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 380.0
PYH1_k127_8046661_1 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000008028 167.0
PYH1_k127_8124300_0 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
PYH1_k127_8124300_1 Flavodoxin - - - 0.0000000000000000000000000000005599 127.0
PYH1_k127_8124300_2 - - - - 0.00000000001051 67.0
PYH1_k127_8124300_3 - - - - 0.000000006276 66.0
PYH1_k127_8151910_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 342.0
PYH1_k127_8151910_1 Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
PYH1_k127_8151910_2 Glutaredoxin K03676,K04771 - 3.4.21.107 0.00000000000000000000000000000000001383 141.0
PYH1_k127_8151910_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000001201 67.0
PYH1_k127_8151910_4 PFAM Cyclic nucleotide-binding K10914 - - 0.000000007407 57.0
PYH1_k127_8176295_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 350.0
PYH1_k127_8176295_1 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 313.0
PYH1_k127_8176295_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 277.0
PYH1_k127_8176295_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000001279 101.0
PYH1_k127_8176295_4 FCD - - - 0.00000000000000000001133 95.0
PYH1_k127_8192159_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 477.0
PYH1_k127_8192159_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 314.0
PYH1_k127_8192159_2 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000001675 69.0
PYH1_k127_8231449_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 373.0
PYH1_k127_8231449_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 310.0
PYH1_k127_8231449_10 - - - - 0.00000001574 64.0
PYH1_k127_8231449_11 - - - - 0.00000004055 62.0
PYH1_k127_8231449_12 - - - - 0.000004944 56.0
PYH1_k127_8231449_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000001411 233.0
PYH1_k127_8231449_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000003078 222.0
PYH1_k127_8231449_4 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000008534 211.0
PYH1_k127_8231449_5 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000002808 198.0
PYH1_k127_8231449_6 - - - - 0.00000000000000000000000000000000000000000003848 170.0
PYH1_k127_8231449_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000001709 151.0
PYH1_k127_8231449_8 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000005805 81.0
PYH1_k127_8231449_9 SnoaL-like domain - - - 0.0000000000005985 74.0
PYH1_k127_8235499_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 582.0
PYH1_k127_8235499_1 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 469.0
PYH1_k127_8235499_10 efflux protein, MATE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001597 267.0
PYH1_k127_8235499_11 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000003057 254.0
PYH1_k127_8235499_12 acetoacetate decarboxylase activity K01574 - 4.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000003311 231.0
PYH1_k127_8235499_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000001523 211.0
PYH1_k127_8235499_14 ACT domain - - - 0.00000000000000000000000000000000000000000000000000002806 192.0
PYH1_k127_8235499_15 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000002227 171.0
PYH1_k127_8235499_16 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000008417 154.0
PYH1_k127_8235499_17 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003388 142.0
PYH1_k127_8235499_18 PFAM Methylated-DNA- protein -cysteine K07443 - - 0.000000000000000000000000001151 115.0
PYH1_k127_8235499_19 Sugar (and other) transporter - - - 0.000000000000000000000005599 115.0
PYH1_k127_8235499_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 452.0
PYH1_k127_8235499_20 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000005313 75.0
PYH1_k127_8235499_21 Major Facilitator Superfamily K03535,K08194 - - 0.000000000001349 79.0
PYH1_k127_8235499_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 407.0
PYH1_k127_8235499_4 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 376.0
PYH1_k127_8235499_5 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 371.0
PYH1_k127_8235499_6 Iron-containing alcohol dehydrogenase K00001,K04072 - 1.1.1.1,1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 365.0
PYH1_k127_8235499_7 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 326.0
PYH1_k127_8235499_8 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004978 267.0
PYH1_k127_8235499_9 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
PYH1_k127_8286864_0 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 431.0
PYH1_k127_8286864_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 320.0
PYH1_k127_8336183_0 ABC-type sugar transport system periplasmic component K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009733 243.0
PYH1_k127_8336183_1 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000009027 231.0
PYH1_k127_8357661_0 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 488.0
PYH1_k127_8357661_1 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 480.0
PYH1_k127_8357661_10 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000001886 234.0
PYH1_k127_8357661_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000113 181.0
PYH1_k127_8357661_12 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000007675 163.0
PYH1_k127_8357661_13 Transcriptional regulator - - - 0.00000000000000000000000000000000005529 141.0
PYH1_k127_8357661_14 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00973 - 2.7.7.24 0.0000000001129 65.0
PYH1_k127_8357661_2 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 442.0
PYH1_k127_8357661_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 359.0
PYH1_k127_8357661_4 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 329.0
PYH1_k127_8357661_5 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
PYH1_k127_8357661_6 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 258.0
PYH1_k127_8357661_7 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000005394 252.0
PYH1_k127_8357661_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001711 231.0
PYH1_k127_8357661_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001242 223.0
PYH1_k127_852364_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 382.0
PYH1_k127_852364_1 sh3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001403 294.0
PYH1_k127_852364_2 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000323 209.0
PYH1_k127_852364_3 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000142 187.0
PYH1_k127_887068_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.552e-304 939.0
PYH1_k127_887068_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 342.0
PYH1_k127_887068_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 295.0
PYH1_k127_887068_3 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004102 282.0
PYH1_k127_887068_4 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009377 282.0
PYH1_k127_887068_5 Protein of unknown function (DUF2167) - - - 0.00000000000000000000000000000000000000000000000000000003879 206.0
PYH1_k127_887068_6 Thioredoxin K03671 - - 0.000000000000000000000000000000000006351 139.0
PYH1_k127_897819_0 CAAX protease self-immunity - - - 0.000000000000000000000001301 109.0
PYH1_k127_897819_1 membrane - - - 0.000000000000001215 86.0
PYH1_k127_897819_2 Phospholipid methyltransferase - - - 0.000000003603 64.0
PYH1_k127_924468_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.354e-319 1002.0
PYH1_k127_924468_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 3.239e-211 664.0
PYH1_k127_924468_11 methyltransferase K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000002829 214.0
PYH1_k127_924468_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000003714 143.0
PYH1_k127_924468_13 spore germination K03605 - - 0.000000000000000000000000000000006928 135.0
PYH1_k127_924468_14 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000004527 121.0
PYH1_k127_924468_15 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000001352 118.0
PYH1_k127_924468_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000001129 93.0
PYH1_k127_924468_17 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.0000000000000004077 78.0
PYH1_k127_924468_18 PFAM Cyclic nucleotide-binding domain - - - 0.00000007449 60.0
PYH1_k127_924468_19 ABC transporter substrate-binding protein K02035 - - 0.0000001994 57.0
PYH1_k127_924468_2 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 4.401e-203 641.0
PYH1_k127_924468_20 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000003517 51.0
PYH1_k127_924468_21 PFAM Integrase catalytic region - - - 0.00004319 48.0
PYH1_k127_924468_22 Domain of unknown function (DUF4190) - - - 0.0008535 47.0
PYH1_k127_924468_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 602.0
PYH1_k127_924468_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 546.0
PYH1_k127_924468_5 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 532.0
PYH1_k127_924468_6 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 509.0
PYH1_k127_924468_7 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 390.0
PYH1_k127_924468_8 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 297.0
PYH1_k127_924468_9 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004911 280.0
PYH1_k127_928158_0 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
PYH1_k127_928158_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 322.0
PYH1_k127_928158_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000008675 136.0
PYH1_k127_928759_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 501.0
PYH1_k127_928759_1 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 474.0
PYH1_k127_928759_2 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002972 273.0
PYH1_k127_928759_3 Predicted membrane protein (DUF2206) - - - 0.0000000000000000000000000000000000000000000000000000000214 222.0
PYH1_k127_928759_4 to orf3 of fosmid clone 4B7mr3 - - - 0.0000000000000000000000000000000000000000000000000499 194.0
PYH1_k127_928759_5 Protein of unknown function (DUF1616) - - - 0.00000002714 61.0
PYH1_k127_948295_0 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 439.0
PYH1_k127_948295_1 PFAM nuclease (SNase domain protein) - - - 0.00000001488 56.0
PYH1_k127_948295_2 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00001476 48.0
PYH1_k127_99029_0 Transposase IS116/IS110/IS902 family - GO:0003674,GO:0003824,GO:0004803,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0032196,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 362.0
PYH1_k127_99029_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000002749 130.0
PYH1_k127_99029_2 Belongs to the 'phage' integrase family - - - 0.0008195 42.0