logo

Overview

ID MAG03162
Name PYH1_bin.59
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Terriglobales
Family JAIQFD01
Genus
Species
Assembly information
Completeness (%) 67.16
Contamination (%) 2.59
GC content (%) 66.0
N50 (bp) 12,989
Genome size (bp) 2,017,988

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1819

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1132162_0 Belongs to the carbamoyltransferase HypF family K04656 - - 2.362e-279 879.0
PYH1_k127_1132162_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 602.0
PYH1_k127_1132162_2 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 578.0
PYH1_k127_1132162_3 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 430.0
PYH1_k127_1132162_4 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 298.0
PYH1_k127_1132162_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000004251 158.0
PYH1_k127_1132162_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000000001031 120.0
PYH1_k127_1132162_7 Hydrogenase nickel incorporation protein hypA K04651 - - 0.00000000000000000007599 94.0
PYH1_k127_1132162_8 High-affinity nickel-transport protein K07241 - - 0.0000000000000000004419 91.0
PYH1_k127_1201024_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 3.497e-196 620.0
PYH1_k127_1201024_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 389.0
PYH1_k127_1201024_2 DREV methyltransferase - - - 0.0000000000001278 72.0
PYH1_k127_12719_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1472.0
PYH1_k127_12719_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1291.0
PYH1_k127_12719_11 phosphorelay signal transduction system - - - 0.00005893 55.0
PYH1_k127_12719_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 366.0
PYH1_k127_12719_3 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 314.0
PYH1_k127_12719_4 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 303.0
PYH1_k127_12719_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004424 252.0
PYH1_k127_12719_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000006624 177.0
PYH1_k127_12719_7 Putative zinc-finger - - - 0.0000000000000000000000000000000006623 135.0
PYH1_k127_12719_8 - - - - 0.000000000000000000000000004155 122.0
PYH1_k127_12719_9 nuclear chromosome segregation - - - 0.00000000000000000000007002 107.0
PYH1_k127_128297_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.469e-224 726.0
PYH1_k127_128297_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 555.0
PYH1_k127_128297_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
PYH1_k127_128297_11 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000168 184.0
PYH1_k127_128297_12 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000002614 165.0
PYH1_k127_128297_13 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000001872 143.0
PYH1_k127_128297_14 methyltransferase activity - - - 0.0000000000000000000000000000000000004458 146.0
PYH1_k127_128297_15 - - - - 0.000000000000000000000000000000002829 135.0
PYH1_k127_128297_16 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000003328 118.0
PYH1_k127_128297_17 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000123 120.0
PYH1_k127_128297_18 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000003822 122.0
PYH1_k127_128297_2 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 495.0
PYH1_k127_128297_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 471.0
PYH1_k127_128297_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 422.0
PYH1_k127_128297_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 376.0
PYH1_k127_128297_6 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004416 275.0
PYH1_k127_128297_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002204 254.0
PYH1_k127_128297_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001311 229.0
PYH1_k127_128297_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000002308 222.0
PYH1_k127_1315311_0 dead deah K03724 - - 0.0 2027.0
PYH1_k127_1315311_1 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001487 285.0
PYH1_k127_1315311_2 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004297 284.0
PYH1_k127_1315311_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000001015 165.0
PYH1_k127_1315311_4 - - - - 0.0000000000000000000000000000000000000009318 155.0
PYH1_k127_1315311_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000003802 106.0
PYH1_k127_1326545_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 462.0
PYH1_k127_1326545_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 323.0
PYH1_k127_1326545_2 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000000000001367 153.0
PYH1_k127_1326545_3 Belongs to the MEMO1 family K06990 - - 0.0009906 45.0
PYH1_k127_132685_0 ABC transporter, transmembrane K18890 - - 8.988e-285 889.0
PYH1_k127_132685_1 Peptidase family M1 domain - - - 5.256e-263 829.0
PYH1_k127_132685_10 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 349.0
PYH1_k127_132685_11 NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
PYH1_k127_132685_12 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000006628 238.0
PYH1_k127_132685_14 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000009487 159.0
PYH1_k127_132685_15 DinB family - - - 0.0000000000000000000000000000000000000001013 161.0
PYH1_k127_132685_16 - - - - 0.0000000000000000000000000000000000007976 141.0
PYH1_k127_132685_17 - - - - 0.00000000000000000000000007198 122.0
PYH1_k127_132685_18 hemerythrin HHE cation binding domain - - - 0.00000000000000000002488 97.0
PYH1_k127_132685_19 - - - - 0.0000000000002225 72.0
PYH1_k127_132685_2 PA domain - - - 1.597e-230 747.0
PYH1_k127_132685_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 560.0
PYH1_k127_132685_4 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 508.0
PYH1_k127_132685_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 497.0
PYH1_k127_132685_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 471.0
PYH1_k127_132685_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 439.0
PYH1_k127_132685_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 426.0
PYH1_k127_132685_9 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 419.0
PYH1_k127_1344005_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 483.0
PYH1_k127_1344005_1 metal-dependent membrane protease - - - 0.0000000000000000000000000000000001164 142.0
PYH1_k127_1344005_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00001569 47.0
PYH1_k127_1369699_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 382.0
PYH1_k127_1369699_1 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003455 271.0
PYH1_k127_1369699_2 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
PYH1_k127_143951_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1614.0
PYH1_k127_143951_1 aconitate hydratase K01681 - 4.2.1.3 0.0 1320.0
PYH1_k127_143951_10 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 462.0
PYH1_k127_143951_11 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 371.0
PYH1_k127_143951_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 361.0
PYH1_k127_143951_13 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 329.0
PYH1_k127_143951_14 FeoA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 284.0
PYH1_k127_143951_15 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008469 284.0
PYH1_k127_143951_16 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000009933 259.0
PYH1_k127_143951_17 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000539 271.0
PYH1_k127_143951_18 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000005529 257.0
PYH1_k127_143951_19 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
PYH1_k127_143951_2 Elongation factor G, domain IV K02355 - - 0.0 1101.0
PYH1_k127_143951_20 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
PYH1_k127_143951_21 peroxiredoxin activity K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000004565 165.0
PYH1_k127_143951_22 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000167 165.0
PYH1_k127_143951_23 DinB family - - - 0.0000000000000000000000000000000004956 144.0
PYH1_k127_143951_24 - - - - 0.00000000000000000000000000000004251 131.0
PYH1_k127_143951_25 - - - - 0.00000000000000000000000001646 120.0
PYH1_k127_143951_26 serine-type peptidase activity K01061,K06889 - 3.1.1.45 0.00000000000000000000001689 110.0
PYH1_k127_143951_27 Bacterial regulatory proteins, tetR family - - - 0.000000000001403 76.0
PYH1_k127_143951_28 Bacterioferritin comigratory K03564 - 1.11.1.15 0.0000000000607 66.0
PYH1_k127_143951_29 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.00000000006109 64.0
PYH1_k127_143951_3 H( )-stimulated, divalent metal cation uptake system K03322 - - 5.783e-201 634.0
PYH1_k127_143951_30 - - - - 0.000008845 55.0
PYH1_k127_143951_4 PFAM Aminotransferase class-III K01845 - 5.4.3.8 1.302e-200 632.0
PYH1_k127_143951_5 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 587.0
PYH1_k127_143951_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 554.0
PYH1_k127_143951_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 510.0
PYH1_k127_143951_8 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 490.0
PYH1_k127_143951_9 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 444.0
PYH1_k127_1485057_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 473.0
PYH1_k127_1485057_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 361.0
PYH1_k127_1485057_2 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 302.0
PYH1_k127_1485057_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 298.0
PYH1_k127_1485057_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004171 253.0
PYH1_k127_1485057_5 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000002661 213.0
PYH1_k127_1485057_6 PFAM Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000424 200.0
PYH1_k127_1485057_7 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000002169 183.0
PYH1_k127_1485057_8 Leucine rich repeat variant - - - 0.0003026 49.0
PYH1_k127_15721_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 295.0
PYH1_k127_15721_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000002722 219.0
PYH1_k127_15721_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000009215 165.0
PYH1_k127_1628702_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1383.0
PYH1_k127_1628702_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 1.845e-288 891.0
PYH1_k127_1628702_2 Asparagine synthase K01953 - 6.3.5.4 2.456e-271 848.0
PYH1_k127_1628702_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.018e-237 756.0
PYH1_k127_1628702_4 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 370.0
PYH1_k127_1628702_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 372.0
PYH1_k127_1628702_6 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 348.0
PYH1_k127_1628702_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 338.0
PYH1_k127_1628702_8 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002757 288.0
PYH1_k127_1628702_9 spore germination K03605 - - 0.00000000000000000000000000000000000000001352 160.0
PYH1_k127_1683959_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.705e-262 815.0
PYH1_k127_1683959_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 9.679e-249 788.0
PYH1_k127_1683959_10 Bacterial Ig-like domain 2 - - - 0.0000000001734 68.0
PYH1_k127_1683959_11 domain, Protein K13735,K20276 - - 0.000003319 56.0
PYH1_k127_1683959_12 PFAM cytochrome c class III - - - 0.000007689 53.0
PYH1_k127_1683959_2 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 556.0
PYH1_k127_1683959_3 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 312.0
PYH1_k127_1683959_4 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001125 278.0
PYH1_k127_1683959_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007765 244.0
PYH1_k127_1683959_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000003583 168.0
PYH1_k127_1683959_7 - - - - 0.00000000000000000000000000000002034 131.0
PYH1_k127_1683959_9 Bacterial Ig-like domain 2 - - - 0.00000000008864 68.0
PYH1_k127_171128_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 8.212e-214 672.0
PYH1_k127_171128_1 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 276.0
PYH1_k127_1739418_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 526.0
PYH1_k127_1739418_1 Belongs to the ATPase B chain family K02109 - - 0.00000000000000000000000000000000001466 141.0
PYH1_k127_17420_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1196.0
PYH1_k127_17420_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 490.0
PYH1_k127_17420_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001354 261.0
PYH1_k127_17420_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001377 227.0
PYH1_k127_17420_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000003219 75.0
PYH1_k127_175646_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 437.0
PYH1_k127_175646_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 428.0
PYH1_k127_175646_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 354.0
PYH1_k127_175646_3 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000003976 128.0
PYH1_k127_176692_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 554.0
PYH1_k127_176692_1 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 496.0
PYH1_k127_176692_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 458.0
PYH1_k127_176692_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 418.0
PYH1_k127_176692_4 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 394.0
PYH1_k127_176692_5 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000001606 210.0
PYH1_k127_176692_6 PBS lyase HEAT-like repeat - - - 0.00000007917 65.0
PYH1_k127_176692_7 PFAM Tetratricopeptide repeat - - - 0.0000001446 62.0
PYH1_k127_1802118_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001597 274.0
PYH1_k127_1802118_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000003279 229.0
PYH1_k127_1802118_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000005268 93.0
PYH1_k127_1802118_4 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000002007 55.0
PYH1_k127_181790_0 PFAM Response regulator receiver domain K07713 - - 1.068e-240 751.0
PYH1_k127_181790_1 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 524.0
PYH1_k127_181790_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000004631 169.0
PYH1_k127_181790_11 anaerobic respiration - - - 0.00000000000000000000000000001014 129.0
PYH1_k127_181790_12 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000452 120.0
PYH1_k127_181790_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000001639 87.0
PYH1_k127_181790_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000002794 70.0
PYH1_k127_181790_15 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000003936 62.0
PYH1_k127_181790_16 Histidine kinase K14489 GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006950,GO:0006952,GO:0006970,GO:0007154,GO:0007165,GO:0007231,GO:0007275,GO:0008150,GO:0008152,GO:0008272,GO:0009267,GO:0009414,GO:0009415,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009743,GO:0009744,GO:0009755,GO:0009784,GO:0009790,GO:0009884,GO:0009885,GO:0009987,GO:0009991,GO:0010015,GO:0010029,GO:0010033,GO:0010035,GO:0010086,GO:0012505,GO:0015698,GO:0016020,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019199,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022622,GO:0023052,GO:0031667,GO:0031668,GO:0031669,GO:0032501,GO:0032502,GO:0032870,GO:0033500,GO:0033554,GO:0034285,GO:0035556,GO:0036211,GO:0038023,GO:0042221,GO:0042578,GO:0042592,GO:0042594,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043424,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048364,GO:0048509,GO:0048580,GO:0048598,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051239,GO:0051704,GO:0051707,GO:0051716,GO:0060089,GO:0065007,GO:0065008,GO:0070887,GO:0071214,GO:0071310,GO:0071322,GO:0071324,GO:0071329,GO:0071368,GO:0071470,GO:0071495,GO:0071496,GO:0071704,GO:0071944,GO:0072348,GO:0098542,GO:0099402,GO:0104004,GO:0140096,GO:1900140,GO:1901564,GO:1901700,GO:1901701,GO:1905392,GO:2000026 2.7.13.3 0.0003186 50.0
PYH1_k127_181790_2 ResB-like family K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 462.0
PYH1_k127_181790_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 372.0
PYH1_k127_181790_4 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 381.0
PYH1_k127_181790_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 340.0
PYH1_k127_181790_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000006525 239.0
PYH1_k127_181790_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000009818 229.0
PYH1_k127_181790_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000005593 213.0
PYH1_k127_181790_9 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000004867 197.0
PYH1_k127_1819315_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1416.0
PYH1_k127_1819315_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 476.0
PYH1_k127_1819315_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000008839 232.0
PYH1_k127_1819315_3 Transcriptional regulator, DeoR family K21601 - - 0.000002547 58.0
PYH1_k127_1821571_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000001037 121.0
PYH1_k127_1821571_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000001274 95.0
PYH1_k127_1821571_2 transposase activity - - - 0.0000000000004856 81.0
PYH1_k127_1821571_3 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.0000003407 59.0
PYH1_k127_1821571_4 - - - - 0.0008665 48.0
PYH1_k127_1827416_0 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 339.0
PYH1_k127_1827416_1 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
PYH1_k127_1827416_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000005553 235.0
PYH1_k127_1827416_3 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000000000000000000001124 172.0
PYH1_k127_1827416_4 Hfq protein - - - 0.0000000000000000000000000000000000000000000024 167.0
PYH1_k127_1831749_0 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 0.0 1368.0
PYH1_k127_1831749_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 570.0
PYH1_k127_1831749_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 372.0
PYH1_k127_1831749_3 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 360.0
PYH1_k127_1833861_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 468.0
PYH1_k127_1833861_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 351.0
PYH1_k127_1833861_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 298.0
PYH1_k127_1833861_3 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000003378 213.0
PYH1_k127_1833861_4 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000000001992 168.0
PYH1_k127_1851216_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 3.554e-224 724.0
PYH1_k127_1851216_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 555.0
PYH1_k127_1851216_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 307.0
PYH1_k127_1851216_3 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002254 264.0
PYH1_k127_1851216_4 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000000000000000007627 136.0
PYH1_k127_1851216_5 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000000000004703 98.0
PYH1_k127_1851216_6 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000001033 74.0
PYH1_k127_1863830_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 385.0
PYH1_k127_1863830_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 295.0
PYH1_k127_1898234_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1317.0
PYH1_k127_1898234_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.955e-232 722.0
PYH1_k127_1898234_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 470.0
PYH1_k127_1898234_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 417.0
PYH1_k127_1898234_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 348.0
PYH1_k127_1898234_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008135 261.0
PYH1_k127_1898234_6 DinB family - - - 0.00000000000000001622 87.0
PYH1_k127_1995913_0 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 2.751e-273 847.0
PYH1_k127_1995913_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 1.088e-262 824.0
PYH1_k127_1995913_2 cell shape determining protein MreB K03569 - - 4.449e-209 652.0
PYH1_k127_1995913_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 545.0
PYH1_k127_1995913_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 466.0
PYH1_k127_1995913_5 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 472.0
PYH1_k127_1995913_6 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 330.0
PYH1_k127_1995913_7 Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 295.0
PYH1_k127_1995913_8 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000003206 195.0
PYH1_k127_1995913_9 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.0000000000000000000000000000000000000001493 154.0
PYH1_k127_2017300_0 signal transduction histidine kinase - - - 9.915e-224 711.0
PYH1_k127_2017300_1 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000002242 215.0
PYH1_k127_2017300_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000001305 194.0
PYH1_k127_2017300_3 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000003573 168.0
PYH1_k127_2074464_0 FMN binding - - - 3.198e-240 752.0
PYH1_k127_2074464_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 8.837e-206 649.0
PYH1_k127_2074464_10 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000006889 154.0
PYH1_k127_2074464_11 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.0000000000000000000000001296 108.0
PYH1_k127_2074464_2 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 559.0
PYH1_k127_2074464_3 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 511.0
PYH1_k127_2074464_4 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 457.0
PYH1_k127_2074464_5 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 393.0
PYH1_k127_2074464_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 310.0
PYH1_k127_2074464_7 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001783 249.0
PYH1_k127_2074464_8 NAD dependent epimerase/dehydratase family K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008614 246.0
PYH1_k127_2074464_9 - - - - 0.000000000000000000000000000000000000000000799 163.0
PYH1_k127_209555_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1518.0
PYH1_k127_209555_1 Sulfatase K01130 - 3.1.6.1 0.0 1433.0
PYH1_k127_209555_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000001142 141.0
PYH1_k127_209555_11 - - - - 0.00000000000000000000000000001799 121.0
PYH1_k127_209555_12 - - - - 0.000000000001425 70.0
PYH1_k127_209555_13 membrane - - - 0.00006316 54.0
PYH1_k127_209555_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 2.919e-225 715.0
PYH1_k127_209555_3 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 463.0
PYH1_k127_209555_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 331.0
PYH1_k127_209555_5 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 301.0
PYH1_k127_209555_6 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 302.0
PYH1_k127_209555_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006255 238.0
PYH1_k127_209555_8 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K02805,K18653 - 2.6.1.104,2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000002785 223.0
PYH1_k127_209555_9 dTDP-6-deoxy-3,4-keto-hexulose isomerase - - - 0.000000000000000000000000000000000000000404 161.0
PYH1_k127_2155733_0 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 509.0
PYH1_k127_2155733_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 463.0
PYH1_k127_2155733_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000228 138.0
PYH1_k127_2155733_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000003057 127.0
PYH1_k127_2174126_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.139e-239 744.0
PYH1_k127_2174126_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 580.0
PYH1_k127_2174126_10 GGDEF domain - - - 0.0000000000002407 79.0
PYH1_k127_2174126_11 Gram-negative bacterial TonB protein C-terminal - - - 0.000000002257 69.0
PYH1_k127_2174126_12 Recombinase - - - 0.00000001203 56.0
PYH1_k127_2174126_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 574.0
PYH1_k127_2174126_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 543.0
PYH1_k127_2174126_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 326.0
PYH1_k127_2174126_5 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003791 287.0
PYH1_k127_2174126_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000002577 195.0
PYH1_k127_2174126_7 PFAM Cupin 2 conserved barrel domain protein K05913 - 1.13.11.41 0.00000000000000000000000000000000000000000003139 166.0
PYH1_k127_2174126_8 Regulatory protein - - - 0.0000000000000000000000000000000000000000002645 166.0
PYH1_k127_2174126_9 Pfam:DUF59 K02612 - - 0.00000000000000000000000000009967 119.0
PYH1_k127_2255515_0 Glycosyl transferase, family 2 - - - 0.0 1470.0
PYH1_k127_2255515_1 Sortilin, neurotensin receptor 3, - - - 0.0 1092.0
PYH1_k127_2255515_10 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 390.0
PYH1_k127_2255515_11 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 352.0
PYH1_k127_2255515_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 314.0
PYH1_k127_2255515_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 327.0
PYH1_k127_2255515_14 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000803 275.0
PYH1_k127_2255515_15 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004914 261.0
PYH1_k127_2255515_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007957 236.0
PYH1_k127_2255515_17 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007293 244.0
PYH1_k127_2255515_18 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000001863 187.0
PYH1_k127_2255515_19 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000001293 131.0
PYH1_k127_2255515_2 Amino acid permease - - - 1.716e-315 984.0
PYH1_k127_2255515_20 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000003794 126.0
PYH1_k127_2255515_21 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000001653 113.0
PYH1_k127_2255515_22 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000006517 108.0
PYH1_k127_2255515_23 - - - - 0.000000000000000004304 91.0
PYH1_k127_2255515_25 DNA integration - - - 0.00000001202 59.0
PYH1_k127_2255515_3 enterobactin catabolic process - - - 5.545e-266 829.0
PYH1_k127_2255515_4 PFAM Radical SAM - - - 8.151e-226 712.0
PYH1_k127_2255515_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 554.0
PYH1_k127_2255515_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 527.0
PYH1_k127_2255515_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 465.0
PYH1_k127_2255515_8 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 449.0
PYH1_k127_2255515_9 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 432.0
PYH1_k127_2263806_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.915e-229 720.0
PYH1_k127_2263806_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 380.0
PYH1_k127_2263806_10 beta-lactamase - - - 0.0000000001767 73.0
PYH1_k127_2263806_11 Serine aminopeptidase, S33 - - - 0.0000000002346 72.0
PYH1_k127_2263806_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 287.0
PYH1_k127_2263806_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001885 261.0
PYH1_k127_2263806_4 PFAM peptidase K16922 - - 0.00000000000000000000000000000000000000000000000002285 205.0
PYH1_k127_2263806_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000002942 178.0
PYH1_k127_2263806_7 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000001723 96.0
PYH1_k127_2263806_8 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000002288 94.0
PYH1_k127_2263806_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000075 91.0
PYH1_k127_2272934_0 FAD linked oxidases, C-terminal domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 576.0
PYH1_k127_2272934_1 PFAM peptidase S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 436.0
PYH1_k127_2272934_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001126 242.0
PYH1_k127_2272934_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000000008193 173.0
PYH1_k127_2301658_0 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 518.0
PYH1_k127_2301658_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 508.0
PYH1_k127_2301658_10 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000009864 124.0
PYH1_k127_2301658_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 461.0
PYH1_k127_2301658_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 387.0
PYH1_k127_2301658_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 348.0
PYH1_k127_2301658_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 265.0
PYH1_k127_2301658_6 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000002275 206.0
PYH1_k127_2301658_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000754 186.0
PYH1_k127_2301658_8 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000000001963 160.0
PYH1_k127_2301658_9 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000164 130.0
PYH1_k127_2303740_0 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 335.0
PYH1_k127_2303740_1 phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
PYH1_k127_2303740_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
PYH1_k127_2303740_3 - - - - 0.0000000001235 63.0
PYH1_k127_2303740_4 - - - - 0.000003286 52.0
PYH1_k127_2369623_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000002493 171.0
PYH1_k127_2369623_1 cheY-homologous receiver domain - - - 0.00000000000000000000102 103.0
PYH1_k127_2369623_2 Y_Y_Y domain - - - 0.000001436 59.0
PYH1_k127_2369623_3 CheW domain protein K13488 - - 0.00005559 54.0
PYH1_k127_2369623_4 Domain of unknown function (DUF4388) - - - 0.0004832 51.0
PYH1_k127_2460668_0 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 8.504e-194 628.0
PYH1_k127_2460668_1 Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 478.0
PYH1_k127_2460668_2 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 335.0
PYH1_k127_2460668_3 lipopolysaccharide metabolic process K08309,K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001177 268.0
PYH1_k127_2460668_4 Cytidylyltransferase K07257 - - 0.000000000000000000000000000000000000000195 155.0
PYH1_k127_2460668_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000001871 119.0
PYH1_k127_2473487_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.673e-303 945.0
PYH1_k127_2473487_1 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000000002002 202.0
PYH1_k127_2473487_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000001344 69.0
PYH1_k127_2492135_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 449.0
PYH1_k127_2492135_1 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 367.0
PYH1_k127_2492135_2 dead deah K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 315.0
PYH1_k127_2492135_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
PYH1_k127_2492135_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 299.0
PYH1_k127_2492135_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000009361 264.0
PYH1_k127_2492135_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000001023 261.0
PYH1_k127_2492135_7 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000005781 208.0
PYH1_k127_2492135_8 - - - - 0.0000000000000000000000000000000000006963 147.0
PYH1_k127_2492135_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001869 146.0
PYH1_k127_251393_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1210.0
PYH1_k127_251393_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 378.0
PYH1_k127_251393_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000003478 150.0
PYH1_k127_2575234_0 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 460.0
PYH1_k127_2575234_1 (ABC) transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 443.0
PYH1_k127_2575234_2 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000001273 182.0
PYH1_k127_2575234_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000008284 102.0
PYH1_k127_2587871_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 477.0
PYH1_k127_2626197_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.413e-262 827.0
PYH1_k127_2626197_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.955e-208 659.0
PYH1_k127_2626197_2 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000001809 213.0
PYH1_k127_2626197_3 - - - - 0.0000000000000000000000000000001963 124.0
PYH1_k127_2626197_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000001244 93.0
PYH1_k127_2626197_5 Regulatory protein, FmdB family - - - 0.000000000004254 67.0
PYH1_k127_2659958_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 6.335e-257 808.0
PYH1_k127_2659958_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 535.0
PYH1_k127_2659958_10 - - - - 0.00000000000000000000000000000000006566 138.0
PYH1_k127_2659958_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000004989 99.0
PYH1_k127_2659958_12 deoxyhypusine monooxygenase activity - - - 0.000000006547 69.0
PYH1_k127_2659958_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 411.0
PYH1_k127_2659958_3 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 393.0
PYH1_k127_2659958_4 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 361.0
PYH1_k127_2659958_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 297.0
PYH1_k127_2659958_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002522 237.0
PYH1_k127_2659958_7 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000006443 215.0
PYH1_k127_2659958_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000002119 184.0
PYH1_k127_2659958_9 - - - - 0.0000000000000000000000000000000000000003579 166.0
PYH1_k127_2667005_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1446.0
PYH1_k127_2667005_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0 1100.0
PYH1_k127_2667005_10 PFAM Peptidase M1, membrane alanine aminopeptidase K08776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 411.0
PYH1_k127_2667005_11 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 325.0
PYH1_k127_2667005_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
PYH1_k127_2667005_13 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000517 237.0
PYH1_k127_2667005_14 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
PYH1_k127_2667005_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
PYH1_k127_2667005_16 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000009727 201.0
PYH1_k127_2667005_17 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000264 173.0
PYH1_k127_2667005_18 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000003027 174.0
PYH1_k127_2667005_19 - - - - 0.0000000000000000000000000000000000001198 147.0
PYH1_k127_2667005_2 Urocanase Rossmann-like domain K01712 - 4.2.1.49 0.0 1013.0
PYH1_k127_2667005_20 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000004098 141.0
PYH1_k127_2667005_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.93e-322 997.0
PYH1_k127_2667005_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 8.152e-284 889.0
PYH1_k127_2667005_5 Belongs to the GSP D family K02453 - - 2.255e-267 845.0
PYH1_k127_2667005_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 3.642e-204 649.0
PYH1_k127_2667005_7 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 515.0
PYH1_k127_2667005_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 473.0
PYH1_k127_2667005_9 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 475.0
PYH1_k127_2677451_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 560.0
PYH1_k127_2677451_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 518.0
PYH1_k127_2677451_2 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000321 177.0
PYH1_k127_2677451_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000003754 175.0
PYH1_k127_2722173_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 502.0
PYH1_k127_2722173_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 552.0
PYH1_k127_2722173_10 - - - - 0.00000000000007962 82.0
PYH1_k127_2722173_2 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
PYH1_k127_2722173_3 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 366.0
PYH1_k127_2722173_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000001203 252.0
PYH1_k127_2722173_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000001897 249.0
PYH1_k127_2722173_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000003504 227.0
PYH1_k127_2722173_7 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000001952 187.0
PYH1_k127_2722173_8 - - - - 0.0000000000000000000002054 98.0
PYH1_k127_2722173_9 Protein of unknown function (DUF1232) - - - 0.00000000000000002236 94.0
PYH1_k127_2736378_0 lipopolysaccharide transport K22110 - - 0.0 1337.0
PYH1_k127_2736378_1 choline dehydrogenase activity - - - 6.7e-267 832.0
PYH1_k127_2736378_10 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 426.0
PYH1_k127_2736378_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 415.0
PYH1_k127_2736378_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 355.0
PYH1_k127_2736378_13 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 353.0
PYH1_k127_2736378_14 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 327.0
PYH1_k127_2736378_15 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
PYH1_k127_2736378_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 297.0
PYH1_k127_2736378_17 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000002523 201.0
PYH1_k127_2736378_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
PYH1_k127_2736378_19 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000658 187.0
PYH1_k127_2736378_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.307e-248 787.0
PYH1_k127_2736378_20 - - - - 0.0000000000000000000000000000000000000001505 154.0
PYH1_k127_2736378_21 YHS domain protein - - - 0.0000000000000000000000000000000000006078 145.0
PYH1_k127_2736378_22 - - - - 0.0000000000000000000000000000000001527 152.0
PYH1_k127_2736378_23 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000002334 136.0
PYH1_k127_2736378_24 Zincin-like metallopeptidase - - - 0.0000000000000000001741 93.0
PYH1_k127_2736378_25 Putative zinc-finger - - - 0.000000000000001059 87.0
PYH1_k127_2736378_27 Putative zinc-finger - - - 0.0000000009469 65.0
PYH1_k127_2736378_3 Glycogen debranching enzyme - - - 1.941e-220 732.0
PYH1_k127_2736378_4 Protein of unknown function (DUF1190) - - - 1.18e-202 665.0
PYH1_k127_2736378_5 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 607.0
PYH1_k127_2736378_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 568.0
PYH1_k127_2736378_7 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 567.0
PYH1_k127_2736378_8 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 505.0
PYH1_k127_2736378_9 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 431.0
PYH1_k127_2736379_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1294.0
PYH1_k127_2736379_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000314 164.0
PYH1_k127_2746352_0 surface antigen variable number - - - 3.288e-292 929.0
PYH1_k127_2746352_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.752e-255 789.0
PYH1_k127_2746352_10 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000008403 194.0
PYH1_k127_2746352_11 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000007477 187.0
PYH1_k127_2746352_13 Transport permease protein K01992 - - 0.0000000000000000000000000000000003528 141.0
PYH1_k127_2746352_14 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000006485 126.0
PYH1_k127_2746352_18 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000001013 78.0
PYH1_k127_2746352_19 Putative adhesin - - - 0.00003285 55.0
PYH1_k127_2746352_2 MoeZ MoeB K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 535.0
PYH1_k127_2746352_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 484.0
PYH1_k127_2746352_4 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 466.0
PYH1_k127_2746352_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 445.0
PYH1_k127_2746352_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 348.0
PYH1_k127_2746352_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003771 275.0
PYH1_k127_2746352_8 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000008764 254.0
PYH1_k127_276035_0 amino acid K03294 - - 3.425e-250 780.0
PYH1_k127_276035_1 amino acid K03294 - - 2.005e-237 743.0
PYH1_k127_276035_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 405.0
PYH1_k127_276035_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 364.0
PYH1_k127_276035_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 323.0
PYH1_k127_276035_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000006846 243.0
PYH1_k127_276035_14 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000004491 161.0
PYH1_k127_276035_15 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000976 127.0
PYH1_k127_276035_16 - - - - 0.0000000002202 69.0
PYH1_k127_276035_2 Sigma-54 interaction domain - - - 1.467e-227 713.0
PYH1_k127_276035_3 PAS domain - - - 6.361e-227 719.0
PYH1_k127_276035_4 Two component regulator propeller - - - 5.47e-209 672.0
PYH1_k127_276035_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 542.0
PYH1_k127_276035_6 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 453.0
PYH1_k127_276035_7 Major facilitator Superfamily K08152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 424.0
PYH1_k127_276035_8 TrkA-C domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 411.0
PYH1_k127_276035_9 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 425.0
PYH1_k127_2799491_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 564.0
PYH1_k127_2799491_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000002989 193.0
PYH1_k127_2844339_0 TonB-dependent Receptor Plug Domain K02014,K16092 - - 1.374e-218 700.0
PYH1_k127_2844339_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001006 281.0
PYH1_k127_2844339_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000001586 231.0
PYH1_k127_2844339_3 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000004241 222.0
PYH1_k127_2844339_4 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000000004272 152.0
PYH1_k127_2844339_5 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000000000000000000004636 131.0
PYH1_k127_2844339_6 Doxx family - - - 0.0000000000000000000000000001673 121.0
PYH1_k127_2844339_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000000000000000004391 111.0
PYH1_k127_2844339_8 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000008146 97.0
PYH1_k127_2864978_0 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 3.211e-230 731.0
PYH1_k127_2864978_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 512.0
PYH1_k127_2864978_2 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 469.0
PYH1_k127_2864978_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000002429 243.0
PYH1_k127_2864978_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001091 145.0
PYH1_k127_2864978_6 NACHT domain - - - 0.000000000000000000000000000002066 136.0
PYH1_k127_2864978_7 TIGRFAM TonB K03832 - - 0.0000000000000000000001893 111.0
PYH1_k127_2864978_8 FHA domain - - - 0.00000000000000000000102 109.0
PYH1_k127_2864978_9 PEGA domain - - - 0.000000005992 67.0
PYH1_k127_2874449_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.357e-278 865.0
PYH1_k127_2874449_1 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 263.0
PYH1_k127_2874449_2 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000000005415 87.0
PYH1_k127_2874449_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000002739 59.0
PYH1_k127_2887983_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 521.0
PYH1_k127_2887983_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 504.0
PYH1_k127_2887983_10 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002675 216.0
PYH1_k127_2887983_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001315 190.0
PYH1_k127_2887983_12 - - - - 0.0000000000000000000000000000000000000000000004902 184.0
PYH1_k127_2887983_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 459.0
PYH1_k127_2887983_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 402.0
PYH1_k127_2887983_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 391.0
PYH1_k127_2887983_5 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 390.0
PYH1_k127_2887983_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 301.0
PYH1_k127_2887983_7 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 263.0
PYH1_k127_2887983_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002269 257.0
PYH1_k127_2887983_9 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000005885 213.0
PYH1_k127_2903392_0 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 488.0
PYH1_k127_2903392_1 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 300.0
PYH1_k127_2903392_2 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000012 239.0
PYH1_k127_2903392_3 belongs to the Fur family K03711,K09823,K09825 - - 0.0000000000000000000000000000000000000003639 156.0
PYH1_k127_2903392_4 Domain of unknown function (DUF4870) - - - 0.000000000000000000000003817 109.0
PYH1_k127_2903392_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00001248 47.0
PYH1_k127_2944769_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.561e-228 714.0
PYH1_k127_2944769_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 599.0
PYH1_k127_2944769_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000002575 227.0
PYH1_k127_2944769_11 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000001648 228.0
PYH1_k127_2944769_12 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000006289 216.0
PYH1_k127_2944769_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
PYH1_k127_2944769_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000009276 207.0
PYH1_k127_2944769_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000007852 203.0
PYH1_k127_2944769_16 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 - - 0.0000000000000000000000000000000000000000000001007 170.0
PYH1_k127_2944769_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000001944 157.0
PYH1_k127_2944769_18 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000008785 153.0
PYH1_k127_2944769_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000002587 147.0
PYH1_k127_2944769_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 357.0
PYH1_k127_2944769_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000005924 119.0
PYH1_k127_2944769_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000002179 120.0
PYH1_k127_2944769_22 Ribosomal protein L30 K02907 - - 0.000000000000000000001192 95.0
PYH1_k127_2944769_23 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000007969 80.0
PYH1_k127_2944769_24 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000005642 70.0
PYH1_k127_2944769_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 325.0
PYH1_k127_2944769_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 313.0
PYH1_k127_2944769_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 286.0
PYH1_k127_2944769_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 287.0
PYH1_k127_2944769_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 287.0
PYH1_k127_2944769_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007934 258.0
PYH1_k127_2944769_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001878 241.0
PYH1_k127_2951520_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 497.0
PYH1_k127_2951520_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 324.0
PYH1_k127_2951520_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000638 205.0
PYH1_k127_2951520_3 response regulator, receiver - - - 0.000000000000000000000000000000000000000000001527 168.0
PYH1_k127_2951520_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000003345 139.0
PYH1_k127_2961682_0 PFAM Organic solvent tolerance protein K04744 - - 6.874e-256 815.0
PYH1_k127_2961682_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.997e-220 695.0
PYH1_k127_2961682_10 TIGRFAM TonB K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 314.0
PYH1_k127_2961682_11 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000103 291.0
PYH1_k127_2961682_12 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000001666 218.0
PYH1_k127_2961682_13 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
PYH1_k127_2961682_14 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000001915 206.0
PYH1_k127_2961682_15 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000374 208.0
PYH1_k127_2961682_16 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000006021 218.0
PYH1_k127_2961682_17 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000000000005411 182.0
PYH1_k127_2961682_18 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000487 152.0
PYH1_k127_2961682_19 response to heat K07090 - - 0.00000000000000000000000000001938 123.0
PYH1_k127_2961682_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.027e-217 685.0
PYH1_k127_2961682_20 pfam rdd - - - 0.000000000000000000000000002532 124.0
PYH1_k127_2961682_21 Preprotein translocase, YajC K03210 - - 0.00000000000000000000000003123 113.0
PYH1_k127_2961682_23 Serine threonine protein kinase K02035 - - 0.0003792 52.0
PYH1_k127_2961682_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 559.0
PYH1_k127_2961682_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 543.0
PYH1_k127_2961682_5 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 419.0
PYH1_k127_2961682_6 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 396.0
PYH1_k127_2961682_7 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 383.0
PYH1_k127_2961682_8 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
PYH1_k127_2961682_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 342.0
PYH1_k127_2962351_0 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009014 243.0
PYH1_k127_2962351_1 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000009226 157.0
PYH1_k127_2962351_2 PBS lyase HEAT-like repeat - - - 0.00000000463 70.0
PYH1_k127_2962351_3 Condensation domain - - - 0.0000005353 62.0
PYH1_k127_2963777_0 twitching motility protein K02670 - - 6.135e-201 630.0
PYH1_k127_2963777_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 603.0
PYH1_k127_2963777_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000001493 199.0
PYH1_k127_2963777_3 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000003152 100.0
PYH1_k127_2993309_0 Prokaryotic cytochrome b561 - - - 2.409e-246 778.0
PYH1_k127_2993309_1 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 373.0
PYH1_k127_2993309_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 319.0
PYH1_k127_300508_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 611.0
PYH1_k127_300508_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 469.0
PYH1_k127_300508_10 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000003916 158.0
PYH1_k127_300508_11 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000001408 133.0
PYH1_k127_300508_12 Glutaredoxin - - - 0.000000000000000008231 84.0
PYH1_k127_300508_13 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00007643 56.0
PYH1_k127_300508_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 422.0
PYH1_k127_300508_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 416.0
PYH1_k127_300508_4 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 400.0
PYH1_k127_300508_5 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 365.0
PYH1_k127_300508_6 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 342.0
PYH1_k127_300508_7 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 338.0
PYH1_k127_300508_8 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001217 289.0
PYH1_k127_300508_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000002112 187.0
PYH1_k127_3028657_0 RNA polymerase sigma-54 factor K03092 - - 1.167e-230 727.0
PYH1_k127_3028657_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.845e-221 704.0
PYH1_k127_3028657_2 lipopolysaccharide transport K09774 - - 5.206e-211 678.0
PYH1_k127_3028657_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 427.0
PYH1_k127_3028657_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 425.0
PYH1_k127_3028657_5 Ribosomal subunit interface protein K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000009731 229.0
PYH1_k127_3028657_6 - - - - 0.0000000000000000000000000000000000000000000000000000000025 203.0
PYH1_k127_3087052_0 Belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 561.0
PYH1_k127_3087052_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15059 - 1.13.11.74,1.13.11.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 424.0
PYH1_k127_3087052_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000002081 190.0
PYH1_k127_3087052_11 MafB19-like deaminase - - - 0.000000000000000000000000000000000000000004732 159.0
PYH1_k127_3087052_12 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000004145 141.0
PYH1_k127_3087052_13 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.00000000000000000000000000003229 123.0
PYH1_k127_3087052_14 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000003186 126.0
PYH1_k127_3087052_15 SMART Tetratricopeptide repeat - - - 0.0000000005616 72.0
PYH1_k127_3087052_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 413.0
PYH1_k127_3087052_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 396.0
PYH1_k127_3087052_4 PFAM Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005788 278.0
PYH1_k127_3087052_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000002566 248.0
PYH1_k127_3087052_6 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004623 256.0
PYH1_k127_3087052_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001811 255.0
PYH1_k127_3087052_8 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001891 255.0
PYH1_k127_3087052_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15058 - - 0.00000000000000000000000000000000000000000000000000000307 203.0
PYH1_k127_311252_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 3.492e-203 638.0
PYH1_k127_311252_1 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 379.0
PYH1_k127_311252_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 384.0
PYH1_k127_311252_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 286.0
PYH1_k127_311252_4 TonB C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005039 252.0
PYH1_k127_311252_5 Transposase K07491 - - 0.00000000000000000000000000000000000000000000000000000002982 200.0
PYH1_k127_313193_0 CarboxypepD_reg-like domain - - - 0.0 1042.0
PYH1_k127_313193_1 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 1.63e-238 752.0
PYH1_k127_313193_10 PilZ domain - - - 0.000000000000000000000000059 113.0
PYH1_k127_313193_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 415.0
PYH1_k127_313193_3 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 362.0
PYH1_k127_313193_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 299.0
PYH1_k127_313193_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 256.0
PYH1_k127_313193_6 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002604 230.0
PYH1_k127_313193_7 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000004935 220.0
PYH1_k127_313193_8 EVE domain - - - 0.00000000000000000000000000000000000000000004078 163.0
PYH1_k127_313193_9 Catalyzes the hydrolysis of nucleoside triphosphates K12944 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429,GO:0047840 - 0.00000000000000000000000000000000001226 147.0
PYH1_k127_3147976_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 416.0
PYH1_k127_3147976_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006435 271.0
PYH1_k127_3147976_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002771 248.0
PYH1_k127_3147976_3 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001602 251.0
PYH1_k127_3147976_4 Protein of unknown function (DUF3106) - - - 0.000000000000000000005138 101.0
PYH1_k127_3147976_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000007706 70.0
PYH1_k127_3147976_6 Protein conserved in bacteria K01061 - 3.1.1.45 0.000000003262 68.0
PYH1_k127_3196326_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.202e-255 800.0
PYH1_k127_3196326_1 Participates in both transcription termination and antitermination K02600 - - 4.036e-211 668.0
PYH1_k127_3196326_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 306.0
PYH1_k127_3196326_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000131 228.0
PYH1_k127_3196326_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000000003135 216.0
PYH1_k127_3196326_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000002835 100.0
PYH1_k127_3196326_6 VanZ like family - - - 0.000000000000007053 89.0
PYH1_k127_3196326_7 Putative stress-induced transcription regulator - - - 0.000004217 51.0
PYH1_k127_3210763_0 SpoIVB peptidase S55 - - - 1.27e-243 766.0
PYH1_k127_3210763_1 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 548.0
PYH1_k127_3210763_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 423.0
PYH1_k127_3210763_3 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 342.0
PYH1_k127_3213385_0 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0 1185.0
PYH1_k127_3213385_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.121e-285 894.0
PYH1_k127_3213385_10 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
PYH1_k127_3213385_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH1_k127_3213385_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000001472 190.0
PYH1_k127_3213385_13 Likely ribonuclease with RNase H fold. K07447 - - 0.00000000000000000000000000000000000000000007301 164.0
PYH1_k127_3213385_2 Involved in the tonB-independent uptake of proteins - - - 2.297e-195 641.0
PYH1_k127_3213385_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 428.0
PYH1_k127_3213385_4 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 432.0
PYH1_k127_3213385_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 404.0
PYH1_k127_3213385_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 379.0
PYH1_k127_3213385_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 344.0
PYH1_k127_3213385_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 328.0
PYH1_k127_3213385_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 285.0
PYH1_k127_3251261_0 Subtilase family - - - 0.00000000002204 77.0
PYH1_k127_3251261_1 Putative zinc-finger - - - 0.00000000003039 74.0
PYH1_k127_3251261_2 signal transduction histidine kinase - - - 0.000000005999 66.0
PYH1_k127_3251261_3 Trypsin-like serine protease - - - 0.00006968 56.0
PYH1_k127_3260182_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 6.461e-296 915.0
PYH1_k127_3260182_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 575.0
PYH1_k127_3260182_10 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000001599 197.0
PYH1_k127_3260182_11 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000001025 169.0
PYH1_k127_3260182_12 - - - - 0.00000000000000000000000000000000000001121 153.0
PYH1_k127_3260182_13 amine dehydrogenase activity - - - 0.00000000000000000000000000000002017 140.0
PYH1_k127_3260182_14 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000006176 125.0
PYH1_k127_3260182_15 S23 ribosomal protein - - - 0.000000000000000000000000000007011 123.0
PYH1_k127_3260182_16 - - - - 0.000000000000000000005041 106.0
PYH1_k127_3260182_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 523.0
PYH1_k127_3260182_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 497.0
PYH1_k127_3260182_4 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 452.0
PYH1_k127_3260182_5 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 432.0
PYH1_k127_3260182_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 426.0
PYH1_k127_3260182_7 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 318.0
PYH1_k127_3260182_8 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 308.0
PYH1_k127_3260182_9 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 292.0
PYH1_k127_328784_0 heat shock protein binding - - - 1.161e-234 744.0
PYH1_k127_328784_1 heat shock protein binding - - - 1.386e-226 715.0
PYH1_k127_328784_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 327.0
PYH1_k127_328784_4 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 280.0
PYH1_k127_3443145_0 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000001164 176.0
PYH1_k127_3443145_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000007113 174.0
PYH1_k127_3443145_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000001531 178.0
PYH1_k127_3443145_3 - - - - 0.00000000000000000000000000000000002075 143.0
PYH1_k127_3443145_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000001775 118.0
PYH1_k127_3450937_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 9.88e-204 644.0
PYH1_k127_3450937_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 555.0
PYH1_k127_3450937_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 456.0
PYH1_k127_3450937_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 398.0
PYH1_k127_3450937_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 397.0
PYH1_k127_3450937_5 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001355 253.0
PYH1_k127_3500830_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2641.0
PYH1_k127_3500830_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2491.0
PYH1_k127_3500830_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 595.0
PYH1_k127_3500830_3 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 465.0
PYH1_k127_3500830_4 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 305.0
PYH1_k127_3500830_5 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005227 284.0
PYH1_k127_3505427_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 426.0
PYH1_k127_351569_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 3.575e-288 909.0
PYH1_k127_351569_1 PFAM 4Fe-4S binding domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 266.0
PYH1_k127_351569_2 DMSO reductase anchor subunit (DmsC) - - - 0.000000000000000000000000000000000000000000000000005824 200.0
PYH1_k127_351569_3 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.00000000000000000000000001434 114.0
PYH1_k127_3516598_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 583.0
PYH1_k127_3516598_1 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
PYH1_k127_3516598_2 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000009177 227.0
PYH1_k127_3538924_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.324e-196 617.0
PYH1_k127_3538924_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000972 80.0
PYH1_k127_3538924_2 Mur ligase middle domain K01925 - 6.3.2.9 0.0001351 46.0
PYH1_k127_359020_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1250.0
PYH1_k127_359020_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 548.0
PYH1_k127_359020_10 Putative esterase K07017 - - 0.0000000000000000008123 89.0
PYH1_k127_359020_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 372.0
PYH1_k127_359020_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000001519 223.0
PYH1_k127_359020_4 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000000001401 193.0
PYH1_k127_359020_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000006314 187.0
PYH1_k127_359020_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000002787 147.0
PYH1_k127_359020_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000002183 147.0
PYH1_k127_359020_8 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000001716 112.0
PYH1_k127_359020_9 PQ loop repeat K15383 - - 0.00000000000000000001768 93.0
PYH1_k127_3610044_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 469.0
PYH1_k127_3610044_1 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 367.0
PYH1_k127_3610044_2 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000009305 173.0
PYH1_k127_3611731_0 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 323.0
PYH1_k127_3611731_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004355 272.0
PYH1_k127_3611731_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005815 254.0
PYH1_k127_3611731_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000000006312 131.0
PYH1_k127_3611731_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001028 79.0
PYH1_k127_3611731_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002438 49.0
PYH1_k127_3726916_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 4.242e-203 649.0
PYH1_k127_3726916_1 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 564.0
PYH1_k127_3726916_10 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000003877 166.0
PYH1_k127_3726916_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 487.0
PYH1_k127_3726916_3 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 404.0
PYH1_k127_3726916_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 332.0
PYH1_k127_3726916_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000008979 250.0
PYH1_k127_3726916_6 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000007038 246.0
PYH1_k127_3726916_7 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000002029 205.0
PYH1_k127_3726916_8 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000002954 197.0
PYH1_k127_3726916_9 methyltransferase - - - 0.000000000000000000000000000000000000000000001827 173.0
PYH1_k127_3742103_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 6.508e-210 663.0
PYH1_k127_3742103_1 alpha beta alpha domain I - - - 2.856e-209 659.0
PYH1_k127_3742103_10 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000000000000000000000000000002655 181.0
PYH1_k127_3742103_11 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000000004181 164.0
PYH1_k127_3742103_12 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.0000000000000000000000002232 114.0
PYH1_k127_3742103_14 antisigma factor binding - - - 0.000000000000000045 91.0
PYH1_k127_3742103_15 membrane protein domain - - - 0.00000004086 60.0
PYH1_k127_3742103_2 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 584.0
PYH1_k127_3742103_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 573.0
PYH1_k127_3742103_4 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 502.0
PYH1_k127_3742103_5 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 469.0
PYH1_k127_3742103_6 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 362.0
PYH1_k127_3742103_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 346.0
PYH1_k127_3742103_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000004669 229.0
PYH1_k127_3742103_9 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000001641 199.0
PYH1_k127_3761663_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1034.0
PYH1_k127_3761663_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 493.0
PYH1_k127_3761663_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 425.0
PYH1_k127_3761663_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 262.0
PYH1_k127_3761663_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002184 223.0
PYH1_k127_3761663_5 PASTA domain K12132 - 2.7.11.1 0.00000000000002302 76.0
PYH1_k127_3763475_0 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
PYH1_k127_3763475_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000001892 201.0
PYH1_k127_3763475_3 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000001125 177.0
PYH1_k127_3768109_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 346.0
PYH1_k127_3768109_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 295.0
PYH1_k127_3768109_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008031 275.0
PYH1_k127_3768109_3 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000001066 226.0
PYH1_k127_3768109_4 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000008931 52.0
PYH1_k127_3806582_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1135.0
PYH1_k127_3806582_1 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 549.0
PYH1_k127_3806582_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000004328 91.0
PYH1_k127_3806582_11 Hydrogenase maturation protease - - - 0.00000000000192 78.0
PYH1_k127_3806582_12 Tetratricopeptide repeat - - - 0.000001971 57.0
PYH1_k127_3806582_2 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 513.0
PYH1_k127_3806582_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 428.0
PYH1_k127_3806582_4 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 353.0
PYH1_k127_3806582_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000107 300.0
PYH1_k127_3806582_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001407 257.0
PYH1_k127_3806582_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000007785 203.0
PYH1_k127_3806582_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000007695 121.0
PYH1_k127_3806582_9 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000001974 96.0
PYH1_k127_3811615_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 2.22e-204 644.0
PYH1_k127_3811615_1 Serine aminopeptidase, S33 K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 416.0
PYH1_k127_3811615_3 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
PYH1_k127_3811615_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006251 245.0
PYH1_k127_3811615_5 - - - - 0.000000000000000000000000000005616 132.0
PYH1_k127_3811615_6 Putative regulatory protein - - - 0.00000000000000000000839 93.0
PYH1_k127_3811615_7 EamA-like transporter family - - - 0.0001929 48.0
PYH1_k127_3830484_0 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000001791 228.0
PYH1_k127_3830484_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000001431 130.0
PYH1_k127_3830484_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000114 117.0
PYH1_k127_3981798_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 591.0
PYH1_k127_3981798_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 429.0
PYH1_k127_3981798_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 426.0
PYH1_k127_3981798_3 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 355.0
PYH1_k127_3981798_4 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 298.0
PYH1_k127_3981798_5 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004362 255.0
PYH1_k127_3981798_6 Hfq protein K03666 - - 0.0000000000000000000000000004658 126.0
PYH1_k127_3981798_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00002678 52.0
PYH1_k127_4011249_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 8.19e-232 724.0
PYH1_k127_4011249_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 505.0
PYH1_k127_4011249_2 Abhydrolase domain containing 18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 467.0
PYH1_k127_4011249_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 388.0
PYH1_k127_4011249_4 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 360.0
PYH1_k127_4011249_5 Psort location Cytoplasmic, score 8.96 K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000007238 175.0
PYH1_k127_4011249_6 DinB superfamily - - - 0.0000000000000000000000000000000000009856 148.0
PYH1_k127_4011249_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000004297 91.0
PYH1_k127_4011249_8 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000002002 62.0
PYH1_k127_4011249_9 PFAM S23 ribosomal protein - - - 0.000000313 56.0
PYH1_k127_4024344_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 482.0
PYH1_k127_4024344_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000003176 181.0
PYH1_k127_4024344_2 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000009017 156.0
PYH1_k127_4129564_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 374.0
PYH1_k127_4129564_1 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001298 186.0
PYH1_k127_4129564_2 Carboxypeptidase regulatory-like domain - - - 0.000000003026 61.0
PYH1_k127_4242600_0 Thiolase, C-terminal domain - - - 9.047e-204 639.0
PYH1_k127_4242600_1 IgA Peptidase M64 - - - 1.574e-200 638.0
PYH1_k127_4242600_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000004493 154.0
PYH1_k127_4242600_11 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000005903 108.0
PYH1_k127_4242600_12 Chlorite dismutase - - - 0.0000000000000004969 83.0
PYH1_k127_4242600_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 582.0
PYH1_k127_4242600_3 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 578.0
PYH1_k127_4242600_4 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 507.0
PYH1_k127_4242600_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 414.0
PYH1_k127_4242600_6 Immune inhibitor A peptidase M6 K09607 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 363.0
PYH1_k127_4242600_8 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00000000000000000000000000000000000000000000000000000000001257 217.0
PYH1_k127_4242600_9 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000005658 190.0
PYH1_k127_4261445_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 343.0
PYH1_k127_4261445_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000409 142.0
PYH1_k127_4261445_2 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.000000000001654 71.0
PYH1_k127_4395669_0 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 1.574e-243 758.0
PYH1_k127_4395669_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
PYH1_k127_4399935_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 547.0
PYH1_k127_4399935_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
PYH1_k127_4399935_2 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000001332 194.0
PYH1_k127_4447364_0 ATPase BadF BadG BcrA BcrD type - - - 3.299e-252 796.0
PYH1_k127_4447364_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 368.0
PYH1_k127_4458814_0 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 432.0
PYH1_k127_4458814_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000005187 175.0
PYH1_k127_4458814_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000146 177.0
PYH1_k127_4479643_0 diguanylate cyclase K02030,K06950,K16923 - - 0.0 1206.0
PYH1_k127_4479643_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.289e-262 824.0
PYH1_k127_4479643_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.19e-212 668.0
PYH1_k127_4479643_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 3.63e-209 658.0
PYH1_k127_4479643_4 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 459.0
PYH1_k127_4479643_5 - - - - 0.000000000000000000000000000000000000000000000000000006676 196.0
PYH1_k127_4479643_6 Protein of unknown function (DUF2393) - - - 0.0000000000000000000000000000000000001101 150.0
PYH1_k127_4531638_0 Heat shock 70 kDa protein K04043 - - 0.0 1066.0
PYH1_k127_4531638_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.173e-305 945.0
PYH1_k127_4531638_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000001447 228.0
PYH1_k127_4531638_11 - - - - 0.00000000000000000000000000000000000000000000000000000000225 207.0
PYH1_k127_4531638_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000002325 206.0
PYH1_k127_4531638_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000008899 210.0
PYH1_k127_4531638_14 MerR HTH family regulatory protein K13640 - - 0.00000000000000000000000000000000000000000000000000005986 189.0
PYH1_k127_4531638_15 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000645 198.0
PYH1_k127_4531638_16 PAP2 superfamily - - - 0.00000000000000000000000000000000000000005569 162.0
PYH1_k127_4531638_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000001576 130.0
PYH1_k127_4531638_18 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000001993 95.0
PYH1_k127_4531638_19 - - - - 0.0000000000000002306 89.0
PYH1_k127_4531638_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.459e-196 618.0
PYH1_k127_4531638_20 isomerase activity K01821 - 5.3.2.6 0.000000000000005648 77.0
PYH1_k127_4531638_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 541.0
PYH1_k127_4531638_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 471.0
PYH1_k127_4531638_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 470.0
PYH1_k127_4531638_6 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 472.0
PYH1_k127_4531638_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 423.0
PYH1_k127_4531638_8 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 403.0
PYH1_k127_4531638_9 3-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001189 245.0
PYH1_k127_4547953_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 3.962e-239 755.0
PYH1_k127_4547953_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 502.0
PYH1_k127_4547953_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 336.0
PYH1_k127_4547953_3 O-methyltransferase - - - 0.0000000000000000000000000000000000000000001226 164.0
PYH1_k127_4547953_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000003708 125.0
PYH1_k127_458070_0 Alpha/beta hydrolase family - - - 3.987e-308 957.0
PYH1_k127_458070_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 452.0
PYH1_k127_458070_10 Protein of unknown function (DUF507) - - - 0.000000000000000000000000000004225 121.0
PYH1_k127_458070_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 308.0
PYH1_k127_458070_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001146 265.0
PYH1_k127_458070_4 Ferredoxin - - - 0.000000000000000000000000000000000000000000000001285 177.0
PYH1_k127_458070_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000006466 181.0
PYH1_k127_458070_6 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000001554 139.0
PYH1_k127_458070_7 ethanolamine catabolic process - - - 0.0000000000000000000000000000000004626 133.0
PYH1_k127_458070_8 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000000009479 131.0
PYH1_k127_458070_9 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000001675 124.0
PYH1_k127_4611803_0 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000001446 218.0
PYH1_k127_4611803_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000005422 208.0
PYH1_k127_4611803_2 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000008519 126.0
PYH1_k127_4696896_0 HD domain - - - 1.661e-239 754.0
PYH1_k127_4696896_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
PYH1_k127_4696896_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000008966 61.0
PYH1_k127_4753715_0 HD domain - - - 7.601e-243 767.0
PYH1_k127_4753715_1 cellulose binding - - - 3.229e-197 662.0
PYH1_k127_4753715_2 PFAM Beta-lactamase - - - 0.0007884 49.0
PYH1_k127_486828_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 2.631e-231 726.0
PYH1_k127_486828_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 473.0
PYH1_k127_486828_10 PFAM Lipid A - - - 0.000000000000000000000000000936 123.0
PYH1_k127_486828_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000001497 85.0
PYH1_k127_486828_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000309 55.0
PYH1_k127_486828_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 418.0
PYH1_k127_486828_3 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 384.0
PYH1_k127_486828_4 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 368.0
PYH1_k127_486828_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 310.0
PYH1_k127_486828_6 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
PYH1_k127_486828_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000009528 160.0
PYH1_k127_486828_8 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000003083 165.0
PYH1_k127_486828_9 Sporulation related domain - - - 0.000000000000000000000000000000000000004511 152.0
PYH1_k127_491420_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 8.968e-255 806.0
PYH1_k127_491420_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
PYH1_k127_491420_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 417.0
PYH1_k127_491420_3 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000001057 201.0
PYH1_k127_491420_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00000000000000000000000000000000008495 141.0
PYH1_k127_5015983_0 Protein kinase domain K12132 - 2.7.11.1 1.047e-257 820.0
PYH1_k127_5015983_1 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 311.0
PYH1_k127_5015983_2 - - - - 0.0000000000000000000000000000000000000002305 155.0
PYH1_k127_5030875_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 3.231e-298 926.0
PYH1_k127_5030875_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 446.0
PYH1_k127_5030875_2 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 357.0
PYH1_k127_5030875_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000002841 219.0
PYH1_k127_5030875_4 O-methyltransferase - - - 0.00000000000000000000000000000000000003881 145.0
PYH1_k127_5030875_5 DinB family - - - 0.00000000000000000000000000000000006404 139.0
PYH1_k127_5030875_6 - - - - 0.0000000000000000000000000002702 128.0
PYH1_k127_5030875_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000000008966 114.0
PYH1_k127_5048659_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 475.0
PYH1_k127_5048659_1 Toprim-like - - - 0.00000000000000000000000000000000000000275 165.0
PYH1_k127_5048659_2 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000001286 144.0
PYH1_k127_5048659_3 Scavenger mRNA decapping enzyme C-term binding - - - 0.000002057 49.0
PYH1_k127_5069107_0 Polysulphide reductase, NrfD K00185 - - 8.14e-212 668.0
PYH1_k127_5069107_1 4Fe-4S dicluster domain K00184 - - 3.472e-199 642.0
PYH1_k127_5069107_2 PFAM Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 593.0
PYH1_k127_5069107_3 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 567.0
PYH1_k127_5069107_4 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 433.0
PYH1_k127_5069107_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 344.0
PYH1_k127_5069107_6 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000006851 175.0
PYH1_k127_5069107_7 Cytochrome c - - - 0.000000000000000000000000000000000000000008199 168.0
PYH1_k127_5085877_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.014e-211 665.0
PYH1_k127_5085877_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 1.194e-195 621.0
PYH1_k127_5085877_10 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000000000000000000001646 138.0
PYH1_k127_5085877_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 596.0
PYH1_k127_5085877_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 473.0
PYH1_k127_5085877_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 327.0
PYH1_k127_5085877_5 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 317.0
PYH1_k127_5085877_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005312 278.0
PYH1_k127_5085877_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001534 274.0
PYH1_k127_5085877_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000004328 144.0
PYH1_k127_5085877_9 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000001195 149.0
PYH1_k127_5091344_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.703e-268 829.0
PYH1_k127_5091344_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.594e-261 811.0
PYH1_k127_5091344_10 - - - - 0.0000000000000000000000000000000000000000000000000001177 193.0
PYH1_k127_5091344_11 - - - - 0.0000000000000000000000000000000000000000000000001802 202.0
PYH1_k127_5091344_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000004545 178.0
PYH1_k127_5091344_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000936 178.0
PYH1_k127_5091344_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000001029 153.0
PYH1_k127_5091344_15 - - - - 0.000000000000000000000000001352 117.0
PYH1_k127_5091344_16 (FHA) domain - - - 0.000000000000000001612 96.0
PYH1_k127_5091344_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.338e-216 678.0
PYH1_k127_5091344_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 472.0
PYH1_k127_5091344_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 469.0
PYH1_k127_5091344_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 411.0
PYH1_k127_5091344_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 407.0
PYH1_k127_5091344_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 339.0
PYH1_k127_5091344_8 Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 315.0
PYH1_k127_5091344_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002318 239.0
PYH1_k127_5093540_0 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 292.0
PYH1_k127_5093540_1 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000005485 119.0
PYH1_k127_5093540_2 Cytochrome c K02305 - - 0.0000000000000000000000000007718 123.0
PYH1_k127_5093540_3 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000001195 128.0
PYH1_k127_5093540_4 4Fe-4S dicluster domain - - - 0.000001783 52.0
PYH1_k127_5162693_0 radical SAM domain protein K22318 - - 3.527e-251 785.0
PYH1_k127_5162693_1 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000000007254 110.0
PYH1_k127_5168819_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1139.0
PYH1_k127_5168819_1 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1107.0
PYH1_k127_5168819_2 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 486.0
PYH1_k127_5168819_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 287.0
PYH1_k127_5168819_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001139 239.0
PYH1_k127_5168819_5 Helix-hairpin-helix motif - - - 0.00000000000000000001857 95.0
PYH1_k127_5209857_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1295.0
PYH1_k127_5209857_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 450.0
PYH1_k127_5209857_2 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 389.0
PYH1_k127_5209857_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 336.0
PYH1_k127_5209857_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000004414 257.0
PYH1_k127_5209857_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000002338 195.0
PYH1_k127_5209857_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000007012 162.0
PYH1_k127_5258593_0 xanthine dehydrogenase, a b hammerhead K03520,K19820 - 1.2.5.3,1.5.99.4 1.445e-263 835.0
PYH1_k127_5258593_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002598 259.0
PYH1_k127_5258593_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000001228 229.0
PYH1_k127_5258593_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000147 185.0
PYH1_k127_5258593_4 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000003055 161.0
PYH1_k127_5258593_5 carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000001784 79.0
PYH1_k127_5285415_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 578.0
PYH1_k127_5285415_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 539.0
PYH1_k127_5285415_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
PYH1_k127_5285415_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 374.0
PYH1_k127_5285415_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005784 270.0
PYH1_k127_5492562_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 461.0
PYH1_k127_5492562_1 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
PYH1_k127_5492562_10 protein kinase related protein - - - 0.0003174 55.0
PYH1_k127_5492562_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 370.0
PYH1_k127_5492562_3 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 351.0
PYH1_k127_5492562_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 359.0
PYH1_k127_5492562_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 352.0
PYH1_k127_5492562_6 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 289.0
PYH1_k127_5492562_7 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000001878 201.0
PYH1_k127_5492562_8 PQQ enzyme repeat - - - 0.000000000000000000000000000006628 140.0
PYH1_k127_5492562_9 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000701 97.0
PYH1_k127_5509409_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1802.0
PYH1_k127_5509409_1 TIGRFAM nitrate reductase, beta subunit K00371 - 1.7.5.1 3.957e-216 680.0
PYH1_k127_5509409_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 408.0
PYH1_k127_5509409_3 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 373.0
PYH1_k127_5509409_4 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000000001317 188.0
PYH1_k127_5509409_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000002016 170.0
PYH1_k127_5509409_6 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000005116 103.0
PYH1_k127_5509409_7 Transcriptional regulator - - - 0.000000000000002508 87.0
PYH1_k127_5557154_0 Protein kinase domain K12132 - 2.7.11.1 7.879e-281 889.0
PYH1_k127_5557154_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 471.0
PYH1_k127_5564679_0 4Fe-4S dicluster domain K00184 - - 0.0 1144.0
PYH1_k127_5564679_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.323e-286 888.0
PYH1_k127_5564679_10 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003701 256.0
PYH1_k127_5564679_11 - - - - 0.00000000000001225 81.0
PYH1_k127_5564679_2 Polysulphide reductase, NrfD K00185 - - 9.394e-223 698.0
PYH1_k127_5564679_3 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 557.0
PYH1_k127_5564679_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 422.0
PYH1_k127_5564679_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 405.0
PYH1_k127_5564679_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 361.0
PYH1_k127_5564679_7 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 299.0
PYH1_k127_5564679_8 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001183 266.0
PYH1_k127_5564679_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 239.0
PYH1_k127_5621853_0 cellulose binding - - - 5.509e-225 700.0
PYH1_k127_5621853_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.531e-202 642.0
PYH1_k127_5621853_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000000000501 160.0
PYH1_k127_5621853_11 - - - - 0.000000000000000000000000000000002337 131.0
PYH1_k127_5621853_2 PFAM Type II secretion system F domain K02653 - - 1.094e-199 628.0
PYH1_k127_5621853_3 Type II/IV secretion system protein K02669 - - 1.047e-195 614.0
PYH1_k127_5621853_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 3.279e-195 622.0
PYH1_k127_5621853_5 DEAD DEAH box helicase K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 451.0
PYH1_k127_5621853_6 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 431.0
PYH1_k127_5621853_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 350.0
PYH1_k127_5621853_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 338.0
PYH1_k127_5621853_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000001648 158.0
PYH1_k127_562776_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 593.0
PYH1_k127_562776_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000002448 236.0
PYH1_k127_562776_3 - - - - 0.0000000000000000000008278 96.0
PYH1_k127_563101_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 496.0
PYH1_k127_563101_1 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001523 270.0
PYH1_k127_563101_10 - K02664 - - 0.0000000000000000005069 99.0
PYH1_k127_563101_2 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000004838 240.0
PYH1_k127_563101_3 Belongs to the HesB IscA family - - - 0.00000000000000000000000000000000000000000000000000000001328 199.0
PYH1_k127_563101_4 - - - - 0.0000000000000000000000000000000000000000000002681 175.0
PYH1_k127_563101_5 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000000000000002977 152.0
PYH1_k127_563101_6 - - - - 0.00000000000000000000000000000000000022 147.0
PYH1_k127_563101_7 Pilus assembly protein K02662 - - 0.000000000000000000000000000002337 135.0
PYH1_k127_563101_8 - - - - 0.0000000000000000000002394 98.0
PYH1_k127_563101_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000001824 93.0
PYH1_k127_5649658_0 Tetratricopeptide repeat - - - 4.327e-256 809.0
PYH1_k127_5649658_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.962e-236 739.0
PYH1_k127_5649658_10 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 294.0
PYH1_k127_5649658_11 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
PYH1_k127_5649658_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001138 232.0
PYH1_k127_5649658_13 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000003078 234.0
PYH1_k127_5649658_14 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000001552 183.0
PYH1_k127_5649658_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002747 177.0
PYH1_k127_5649658_16 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000000000000000555 168.0
PYH1_k127_5649658_17 GtrA-like protein - - - 0.00000000000000000000000000000618 132.0
PYH1_k127_5649658_18 phosphorelay signal transduction system - - - 0.00000000000000000000000006859 118.0
PYH1_k127_5649658_19 STAS domain - - - 0.000000000000003727 79.0
PYH1_k127_5649658_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 556.0
PYH1_k127_5649658_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02275,K17686 - 1.9.3.1,3.6.3.54 0.000005684 57.0
PYH1_k127_5649658_3 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 561.0
PYH1_k127_5649658_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 535.0
PYH1_k127_5649658_5 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 511.0
PYH1_k127_5649658_6 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 444.0
PYH1_k127_5649658_7 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
PYH1_k127_5649658_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
PYH1_k127_5649658_9 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
PYH1_k127_565423_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 5.904e-316 977.0
PYH1_k127_565423_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 1.074e-197 621.0
PYH1_k127_565423_10 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007048 239.0
PYH1_k127_565423_11 - - - - 0.00000000000000000000000000000000000000000001257 181.0
PYH1_k127_565423_12 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000000000000000000000008069 138.0
PYH1_k127_565423_13 EamA-like transporter family - - - 0.000000000000000000000000000002176 131.0
PYH1_k127_565423_14 membrane - - - 0.00000000000000000000000000001635 121.0
PYH1_k127_565423_15 Cytochrome oxidase complex assembly protein 1 - - - 0.000000000000000003824 91.0
PYH1_k127_565423_2 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 574.0
PYH1_k127_565423_3 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 568.0
PYH1_k127_565423_4 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 529.0
PYH1_k127_565423_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 490.0
PYH1_k127_565423_6 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 465.0
PYH1_k127_565423_7 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 450.0
PYH1_k127_565423_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 392.0
PYH1_k127_565423_9 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 314.0
PYH1_k127_570491_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 589.0
PYH1_k127_570491_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 525.0
PYH1_k127_570491_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000001294 124.0
PYH1_k127_5705046_0 GTP-binding protein TypA K06207 - - 0.0 1012.0
PYH1_k127_5705046_1 class II (D K K01893 - 6.1.1.22 4.932e-231 732.0
PYH1_k127_5705046_10 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 421.0
PYH1_k127_5705046_11 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 366.0
PYH1_k127_5705046_12 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 370.0
PYH1_k127_5705046_13 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 370.0
PYH1_k127_5705046_14 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 363.0
PYH1_k127_5705046_15 OmpA family K02557,K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 359.0
PYH1_k127_5705046_16 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 351.0
PYH1_k127_5705046_17 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 341.0
PYH1_k127_5705046_18 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 321.0
PYH1_k127_5705046_19 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 304.0
PYH1_k127_5705046_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.374e-217 690.0
PYH1_k127_5705046_20 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 297.0
PYH1_k127_5705046_21 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 299.0
PYH1_k127_5705046_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 293.0
PYH1_k127_5705046_23 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
PYH1_k127_5705046_24 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006163 273.0
PYH1_k127_5705046_25 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001136 260.0
PYH1_k127_5705046_26 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000005778 211.0
PYH1_k127_5705046_27 TIGRFAM Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000003603 201.0
PYH1_k127_5705046_28 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.00000000000000000000000000000000000000000000000003174 190.0
PYH1_k127_5705046_29 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000002516 175.0
PYH1_k127_5705046_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 580.0
PYH1_k127_5705046_30 - - - - 0.0000000000000000000000000000000000000000001173 166.0
PYH1_k127_5705046_31 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000001589 174.0
PYH1_k127_5705046_32 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000004358 164.0
PYH1_k127_5705046_33 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000008069 147.0
PYH1_k127_5705046_34 Pfam:N_methyl_2 - - - 0.00000000000000000000000000000000008799 140.0
PYH1_k127_5705046_35 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000002674 134.0
PYH1_k127_5705046_36 cyclic nucleotide binding K01420,K21556,K21562 - - 0.0000000000000000000000000000000003122 137.0
PYH1_k127_5705046_38 Pfam:N_methyl_2 - - - 0.00000000000000000000000000000001791 132.0
PYH1_k127_5705046_39 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000005412 122.0
PYH1_k127_5705046_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 572.0
PYH1_k127_5705046_40 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000006405 125.0
PYH1_k127_5705046_41 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000001207 127.0
PYH1_k127_5705046_42 Protein conserved in bacteria - - - 0.0000000000000000000000000003089 123.0
PYH1_k127_5705046_43 Ribosomal L32p protein family K02911 - - 0.000000000000000000000000005278 112.0
PYH1_k127_5705046_44 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000005133 104.0
PYH1_k127_5705046_45 - - - - 0.000000000000002961 77.0
PYH1_k127_5705046_46 - - - - 0.000000000000003686 87.0
PYH1_k127_5705046_47 acetyltransferase - - - 0.00000000000001386 74.0
PYH1_k127_5705046_49 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000029 56.0
PYH1_k127_5705046_5 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 529.0
PYH1_k127_5705046_50 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001485 45.0
PYH1_k127_5705046_6 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 508.0
PYH1_k127_5705046_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 466.0
PYH1_k127_5705046_8 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 452.0
PYH1_k127_5705046_9 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 424.0
PYH1_k127_5843210_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244,K00278 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 4.549e-280 872.0
PYH1_k127_5843210_1 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 360.0
PYH1_k127_5843210_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001291 218.0
PYH1_k127_5843210_3 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.000000000000000000000000000000001435 132.0
PYH1_k127_5843210_4 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.000000000000000000000004926 116.0
PYH1_k127_5843210_5 Tfp pilus assembly protein FimV - - - 0.0000000000000000000002547 103.0
PYH1_k127_5890520_0 Trypsin K04771 - 3.4.21.107 2.741e-206 654.0
PYH1_k127_5890520_1 Aldehyde dehydrogenase family K22445 - 1.2.99.10 5.387e-199 632.0
PYH1_k127_5890520_10 outer membrane efflux protein - - - 0.0000000000000000000000000000005625 126.0
PYH1_k127_5890520_11 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000002429 126.0
PYH1_k127_5890520_12 - - - - 0.000000000000000000117 93.0
PYH1_k127_5890520_2 Amidohydrolase family - - - 5.62e-196 626.0
PYH1_k127_5890520_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 520.0
PYH1_k127_5890520_4 Peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 454.0
PYH1_k127_5890520_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 431.0
PYH1_k127_5890520_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 311.0
PYH1_k127_5890520_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
PYH1_k127_5890520_8 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
PYH1_k127_5890520_9 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000007057 147.0
PYH1_k127_5905232_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 462.0
PYH1_k127_5905232_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 419.0
PYH1_k127_5905232_2 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
PYH1_k127_5905232_3 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000007566 186.0
PYH1_k127_5905232_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000001699 112.0
PYH1_k127_5947610_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 534.0
PYH1_k127_5947610_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 469.0
PYH1_k127_5947610_2 4Fe-4S binding domain K08358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 319.0
PYH1_k127_5947610_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001843 279.0
PYH1_k127_5947610_4 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000002673 187.0
PYH1_k127_5959081_0 DNA polymerase X family K02347 - - 9.029e-263 825.0
PYH1_k127_5959081_1 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000001008 192.0
PYH1_k127_5959081_2 Cold shock protein K03704 - - 0.00000000000000000000000000000005666 125.0
PYH1_k127_5959081_3 - - - - 0.00000000000000000000000000002147 131.0
PYH1_k127_5959081_4 Protein conserved in bacteria - - - 0.000000000000000000002878 94.0
PYH1_k127_5959081_5 nadp oxidoreductase, coenzyme f420-dependent - - - 0.0002033 46.0
PYH1_k127_597685_0 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001074 248.0
PYH1_k127_597685_1 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000006878 200.0
PYH1_k127_597685_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000581 121.0
PYH1_k127_6050458_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 1.726e-246 784.0
PYH1_k127_6050458_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.659e-229 715.0
PYH1_k127_6050458_10 NUDIX domain - - - 0.00000000000000000000000000000000000000000000002524 173.0
PYH1_k127_6050458_11 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000004165 180.0
PYH1_k127_6050458_12 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000133 121.0
PYH1_k127_6050458_13 - - - - 0.00000000000000000000000001236 126.0
PYH1_k127_6050458_14 Forkhead associated domain - - - 0.0000000000000001475 89.0
PYH1_k127_6050458_15 SNARE associated Golgi protein - - - 0.0000000002002 62.0
PYH1_k127_6050458_2 COGs COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 6.823e-212 672.0
PYH1_k127_6050458_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.2e-211 666.0
PYH1_k127_6050458_4 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 359.0
PYH1_k127_6050458_5 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 362.0
PYH1_k127_6050458_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 298.0
PYH1_k127_6050458_7 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 285.0
PYH1_k127_6050458_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001488 271.0
PYH1_k127_6050458_9 aminopeptidase activity K07004 - - 0.000000000000000000000000000000000000000000000000000000006888 226.0
PYH1_k127_6060990_0 Pyridoxal-dependent decarboxylase conserved domain - - - 1.206e-209 662.0
PYH1_k127_6060990_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 487.0
PYH1_k127_6076206_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.635e-198 624.0
PYH1_k127_6076206_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002805 244.0
PYH1_k127_6076206_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000001452 162.0
PYH1_k127_6076206_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000001446 156.0
PYH1_k127_611855_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 6.512e-252 818.0
PYH1_k127_611855_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 1.444e-196 656.0
PYH1_k127_6196712_0 Zinc-binding dehydrogenase K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 511.0
PYH1_k127_6196712_1 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 458.0
PYH1_k127_6196712_2 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 408.0
PYH1_k127_6196712_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001946 284.0
PYH1_k127_6196712_4 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000000000000000000000000004192 209.0
PYH1_k127_6196712_5 Transposase K07497 - - 0.00000000000000000000000000000000000000002541 153.0
PYH1_k127_6233879_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 518.0
PYH1_k127_6233879_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 358.0
PYH1_k127_6233879_2 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 295.0
PYH1_k127_6349771_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 6.117e-311 970.0
PYH1_k127_6349771_1 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 341.0
PYH1_k127_6355336_0 Histidine kinase K02482,K03557 - 2.7.13.3 1.817e-274 867.0
PYH1_k127_6355336_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 586.0
PYH1_k127_6355336_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 405.0
PYH1_k127_6355336_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
PYH1_k127_6355336_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000006738 209.0
PYH1_k127_6355336_5 Protein of unknown function with PCYCGC motif - - - 0.0000000000000000000000000000000000000000002439 164.0
PYH1_k127_6355336_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000009917 90.0
PYH1_k127_6357002_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1019.0
PYH1_k127_6357002_1 PFAM isocitrate isopropylmalate dehydrogenase K00031 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 613.0
PYH1_k127_6357002_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 253.0
PYH1_k127_6357002_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
PYH1_k127_6357002_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000006914 220.0
PYH1_k127_6357002_13 - - - - 0.00000000000000000000000000000000000000000000001066 183.0
PYH1_k127_6357002_14 GAF domain - - - 0.00000000000000000000000000000000000000000002053 168.0
PYH1_k127_6357002_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 522.0
PYH1_k127_6357002_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 479.0
PYH1_k127_6357002_4 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 488.0
PYH1_k127_6357002_5 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 434.0
PYH1_k127_6357002_6 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 419.0
PYH1_k127_6357002_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 313.0
PYH1_k127_6357002_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 301.0
PYH1_k127_6357002_9 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 295.0
PYH1_k127_6391951_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.931e-301 945.0
PYH1_k127_6391951_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000008856 239.0
PYH1_k127_6391951_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001112 241.0
PYH1_k127_6391951_3 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000002108 123.0
PYH1_k127_6391951_4 Protein of unknown function (DUF2892) - - - 0.00000000000000000003041 93.0
PYH1_k127_6391951_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000004952 75.0
PYH1_k127_6433617_0 Radical SAM - - - 0.0 1129.0
PYH1_k127_6433617_1 Radical SAM superfamily K06937 - - 5.423e-260 814.0
PYH1_k127_6433617_10 pilus assembly protein PilW - - - 0.0000006914 60.0
PYH1_k127_6433617_11 Pilus assembly protein PilX K02673 - - 0.00001125 58.0
PYH1_k127_6433617_12 general secretion pathway protein G K02456 - - 0.00004338 53.0
PYH1_k127_6433617_2 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 285.0
PYH1_k127_6433617_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006662 263.0
PYH1_k127_6433617_4 - - - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
PYH1_k127_6433617_5 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000000001775 192.0
PYH1_k127_6433617_6 - - - - 0.00000000000000000000000000000000000000000004957 168.0
PYH1_k127_6433617_8 integral membrane protein - - - 0.000000000000001858 79.0
PYH1_k127_6433617_9 - - - - 0.00000002547 60.0
PYH1_k127_6491832_0 amino acid - - - 3.343e-204 645.0
PYH1_k127_6491832_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003873 254.0
PYH1_k127_6551697_0 Carboxypeptidase regulatory-like domain - - - 2.775e-317 1013.0
PYH1_k127_6551697_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 2.9e-290 909.0
PYH1_k127_6551697_10 cellulose binding - - - 0.0000000000001042 83.0
PYH1_k127_6551697_2 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 495.0
PYH1_k127_6551697_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 469.0
PYH1_k127_6551697_4 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 396.0
PYH1_k127_6551697_5 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 323.0
PYH1_k127_6551697_6 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
PYH1_k127_6551697_7 polyphosphate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000345 232.0
PYH1_k127_6551697_8 CHAD - - - 0.000000000000000000005489 104.0
PYH1_k127_6613082_0 - - - - 0.00000000000000000000007083 101.0
PYH1_k127_6628885_0 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 463.0
PYH1_k127_6628885_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 407.0
PYH1_k127_6628885_2 Na+/H+ antiporter family K03315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003617 279.0
PYH1_k127_6628885_3 - - - - 0.0000000000000000000000000000000000000000000000000002346 186.0
PYH1_k127_6630053_0 PFAM Type II secretion system protein E K02652 - - 8.58e-209 657.0
PYH1_k127_6630053_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 456.0
PYH1_k127_6630053_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 369.0
PYH1_k127_6630053_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 299.0
PYH1_k127_6630053_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003725 279.0
PYH1_k127_6630053_5 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
PYH1_k127_6630053_6 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000674 214.0
PYH1_k127_6630053_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000004308 177.0
PYH1_k127_6723215_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.261e-285 889.0
PYH1_k127_6723215_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.604e-259 812.0
PYH1_k127_6723215_10 Putative zinc-finger - - - 0.000000000000000000000000000000000000002011 160.0
PYH1_k127_6723215_11 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000005305 149.0
PYH1_k127_6723215_13 - - - - 0.00005352 53.0
PYH1_k127_6723215_2 synthetase, class II (G H P K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 612.0
PYH1_k127_6723215_3 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 362.0
PYH1_k127_6723215_4 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 348.0
PYH1_k127_6723215_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 323.0
PYH1_k127_6723215_6 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
PYH1_k127_6723215_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
PYH1_k127_6723215_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003734 257.0
PYH1_k127_6723215_9 - - - - 0.0000000000000000000000000000000000000000000000766 176.0
PYH1_k127_6745904_0 PFAM peptidase M13 K01415 - 3.4.24.71 1.097e-262 825.0
PYH1_k127_6745904_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 526.0
PYH1_k127_6745904_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 460.0
PYH1_k127_6745904_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 407.0
PYH1_k127_6745904_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000002369 145.0
PYH1_k127_6755981_0 Bacterial regulatory protein, Fis family K07713 - - 1.169e-205 661.0
PYH1_k127_6755981_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 358.0
PYH1_k127_6755981_2 - - - - 0.000002905 53.0
PYH1_k127_6760372_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 5.173e-236 737.0
PYH1_k127_6760372_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 7.168e-236 743.0
PYH1_k127_6760372_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 425.0
PYH1_k127_6760372_11 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 384.0
PYH1_k127_6760372_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 381.0
PYH1_k127_6760372_13 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 380.0
PYH1_k127_6760372_14 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 362.0
PYH1_k127_6760372_15 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 326.0
PYH1_k127_6760372_16 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 325.0
PYH1_k127_6760372_17 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 323.0
PYH1_k127_6760372_18 synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 309.0
PYH1_k127_6760372_19 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 309.0
PYH1_k127_6760372_2 extracellular solute-binding protein, family 5 K02035 - - 1.178e-204 652.0
PYH1_k127_6760372_20 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 292.0
PYH1_k127_6760372_21 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 272.0
PYH1_k127_6760372_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000002715 238.0
PYH1_k127_6760372_23 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000004886 191.0
PYH1_k127_6760372_25 - - - - 0.00000000000000000000002077 107.0
PYH1_k127_6760372_26 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000006348 97.0
PYH1_k127_6760372_27 - - - - 0.0000000000000000004393 93.0
PYH1_k127_6760372_28 nuclear chromosome segregation - - - 0.00000000000000003423 85.0
PYH1_k127_6760372_3 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 612.0
PYH1_k127_6760372_4 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 576.0
PYH1_k127_6760372_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 584.0
PYH1_k127_6760372_6 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 494.0
PYH1_k127_6760372_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 473.0
PYH1_k127_6760372_8 Belongs to the GSP D family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 479.0
PYH1_k127_6760372_9 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 450.0
PYH1_k127_6784708_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1031.0
PYH1_k127_6784708_1 Fumarase C C-terminus K01744 - 4.3.1.1 2.478e-269 844.0
PYH1_k127_6784708_2 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 3.272e-245 762.0
PYH1_k127_6784708_3 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 403.0
PYH1_k127_6784708_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000005303 58.0
PYH1_k127_6802229_0 Sodium:solute symporter family - - - 1.498e-296 920.0
PYH1_k127_6802229_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.061e-265 827.0
PYH1_k127_6802229_2 Oligoendopeptidase f - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 482.0
PYH1_k127_6802229_3 Aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 354.0
PYH1_k127_6802229_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
PYH1_k127_6802229_5 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 321.0
PYH1_k127_6802229_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000001005 210.0
PYH1_k127_6802229_7 mttA/Hcf106 family K03117 - - 0.000000000000000009535 85.0
PYH1_k127_6817786_0 PFAM Glycosyl transferase family 2 - - - 3.71e-282 876.0
PYH1_k127_6817786_1 Tetratricopeptide repeat - - - 2.556e-201 641.0
PYH1_k127_6817786_10 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000000000000000006587 195.0
PYH1_k127_6817786_11 BioY family K03523 - - 0.0000000000000000000000000000000000000000002013 165.0
PYH1_k127_6817786_12 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.0000000000000000001782 89.0
PYH1_k127_6817786_14 - - - - 0.00000000000000008951 87.0
PYH1_k127_6817786_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 5.019e-194 609.0
PYH1_k127_6817786_3 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 517.0
PYH1_k127_6817786_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 473.0
PYH1_k127_6817786_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 431.0
PYH1_k127_6817786_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 436.0
PYH1_k127_6817786_7 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 329.0
PYH1_k127_6817786_8 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 275.0
PYH1_k127_6817786_9 - - - - 0.000000000000000000000000000000000000000000000000000002011 196.0
PYH1_k127_6862173_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 464.0
PYH1_k127_6862173_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 411.0
PYH1_k127_6862173_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
PYH1_k127_6862173_3 transmembrane transporter activity K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 279.0
PYH1_k127_6862173_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006375 263.0
PYH1_k127_6862173_5 sequence-specific DNA binding - - - 0.000000000000000000000001254 116.0
PYH1_k127_6873046_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 316.0
PYH1_k127_6873046_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004701 280.0
PYH1_k127_6909206_0 cellulose binding - - - 1.865e-239 762.0
PYH1_k127_6910172_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1014.0
PYH1_k127_6910172_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.111e-284 887.0
PYH1_k127_6910172_10 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000003386 116.0
PYH1_k127_6910172_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.902e-275 869.0
PYH1_k127_6910172_3 Sigma factor PP2C-like phosphatases - - - 1.384e-230 730.0
PYH1_k127_6910172_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 319.0
PYH1_k127_6910172_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002822 279.0
PYH1_k127_6910172_6 DinB superfamily - - - 0.0000000000000000000000000000000000000000000003467 176.0
PYH1_k127_6910172_7 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000000000001786 162.0
PYH1_k127_6910172_8 - - - - 0.0000000000000000000000000000000000000000371 154.0
PYH1_k127_6910172_9 - - - - 0.0000000000000000000000000000000003296 133.0
PYH1_k127_6913474_0 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 578.0
PYH1_k127_6913474_1 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 560.0
PYH1_k127_6913474_10 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 265.0
PYH1_k127_6913474_11 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000136 257.0
PYH1_k127_6913474_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007333 232.0
PYH1_k127_6913474_13 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000004677 175.0
PYH1_k127_6913474_14 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000001216 162.0
PYH1_k127_6913474_15 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000006768 158.0
PYH1_k127_6913474_16 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000002309 141.0
PYH1_k127_6913474_17 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000001777 122.0
PYH1_k127_6913474_18 Membrane - - - 0.000000000000000000002418 108.0
PYH1_k127_6913474_2 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 487.0
PYH1_k127_6913474_3 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 477.0
PYH1_k127_6913474_4 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 410.0
PYH1_k127_6913474_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 411.0
PYH1_k127_6913474_6 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 392.0
PYH1_k127_6913474_7 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 385.0
PYH1_k127_6913474_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
PYH1_k127_6913474_9 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004449 284.0
PYH1_k127_6938964_0 Insulinase (Peptidase family M16) K07263 - - 3.593e-203 642.0
PYH1_k127_6938964_1 Metal binding domain of Ada K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 299.0
PYH1_k127_6938964_2 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000006678 200.0
PYH1_k127_6938964_3 CTP synthase K01937 - 6.3.4.2 0.0000000000000000000000756 103.0
PYH1_k127_6938964_4 CTP synthase K01937 - 6.3.4.2 0.0000000000001542 73.0
PYH1_k127_6965953_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0 1021.0
PYH1_k127_6965953_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 1.892e-195 625.0
PYH1_k127_6965953_2 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 595.0
PYH1_k127_6965953_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
PYH1_k127_6965953_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000008887 216.0
PYH1_k127_6965953_5 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000143 212.0
PYH1_k127_6965953_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001218 179.0
PYH1_k127_6965953_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000005589 164.0
PYH1_k127_6967038_0 Hydrolase CocE NonD family - - - 2.081e-303 946.0
PYH1_k127_6967038_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 492.0
PYH1_k127_6967038_10 - - - - 0.00000000000000000000000000000000000008749 147.0
PYH1_k127_6967038_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 318.0
PYH1_k127_6967038_3 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 314.0
PYH1_k127_6967038_4 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 303.0
PYH1_k127_6967038_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 298.0
PYH1_k127_6967038_6 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001436 267.0
PYH1_k127_6967038_7 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008549 259.0
PYH1_k127_6967038_8 Glutathione peroxidase K02199 - - 0.00000000000000000000000000000000000000000000000001983 186.0
PYH1_k127_6967038_9 Disulphide bond corrector protein DsbC - - - 0.00000000000000000000000000000000000002516 151.0
PYH1_k127_698287_0 Peptidase M56 - - - 2.073e-219 694.0
PYH1_k127_698287_1 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 478.0
PYH1_k127_698287_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 395.0
PYH1_k127_698287_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001436 268.0
PYH1_k127_7028044_0 AMP-binding enzyme C-terminal domain - - - 3.214e-198 631.0
PYH1_k127_7028044_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
PYH1_k127_7028044_2 PFAM Short-chain dehydrogenase reductase SDR K00059,K03793 - 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 289.0
PYH1_k127_7028044_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000001893 251.0
PYH1_k127_7028044_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000008877 198.0
PYH1_k127_7028044_6 PFAM Glutaredoxin 2 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000004976 68.0
PYH1_k127_7028044_7 Transport permease protein K01992 - - 0.0000008265 59.0
PYH1_k127_7087348_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1164.0
PYH1_k127_7087348_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 544.0
PYH1_k127_7087348_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 320.0
PYH1_k127_7087348_3 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000144 193.0
PYH1_k127_7087348_4 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000001022 97.0
PYH1_k127_7087348_5 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000001453 91.0
PYH1_k127_7097324_0 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 561.0
PYH1_k127_7097324_1 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 489.0
PYH1_k127_7097324_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000152 276.0
PYH1_k127_7097324_3 YdjC-like protein - - - 0.0000000004745 62.0
PYH1_k127_7102506_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1283.0
PYH1_k127_7102506_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 519.0
PYH1_k127_7102506_10 - - - - 0.00000000000000000000000000004841 118.0
PYH1_k127_7102506_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 412.0
PYH1_k127_7102506_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
PYH1_k127_7102506_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 285.0
PYH1_k127_7102506_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000008953 220.0
PYH1_k127_7102506_6 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000000006651 193.0
PYH1_k127_7102506_7 Rhomboid K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000001205 200.0
PYH1_k127_7102506_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000001069 160.0
PYH1_k127_7102506_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000001451 136.0
PYH1_k127_7156916_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 443.0
PYH1_k127_7156916_2 - - - - 0.000000000000000000000000000000000000000000000000003581 188.0
PYH1_k127_7193133_0 - K17285 - - 0.0 1384.0
PYH1_k127_7193133_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.047e-213 673.0
PYH1_k127_7193133_10 - - - - 0.0000000000000000000000000000000000000000000001008 182.0
PYH1_k127_7193133_11 ATPase activity - - - 0.000000000000000000000000000000000000008697 161.0
PYH1_k127_7193133_12 - - - - 0.0000000000000000000000000000000001874 136.0
PYH1_k127_7193133_13 Transposase IS200 like K07491 - - 0.00000000000000000000000000000008901 135.0
PYH1_k127_7193133_14 - - - - 0.000000000000000000000000000003149 124.0
PYH1_k127_7193133_2 histone H2A K63-linked ubiquitination K00925,K08884,K11894 - 2.7.11.1,2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 467.0
PYH1_k127_7193133_3 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 372.0
PYH1_k127_7193133_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 321.0
PYH1_k127_7193133_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 305.0
PYH1_k127_7193133_6 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009614 265.0
PYH1_k127_7193133_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000419 203.0
PYH1_k127_7193133_8 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000001091 183.0
PYH1_k127_7193133_9 - - - - 0.00000000000000000000000000000000000000000000001862 181.0
PYH1_k127_7232970_0 Histidine kinase K02482 - 2.7.13.3 8.401e-313 993.0
PYH1_k127_7232970_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 3.424e-243 769.0
PYH1_k127_7232970_10 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000002369 162.0
PYH1_k127_7232970_11 Response regulator, receiver - - - 0.00000000000000000000000000000000000001191 153.0
PYH1_k127_7232970_13 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000003339 116.0
PYH1_k127_7232970_14 PhoQ Sensor - - - 0.000000000000000000000145 101.0
PYH1_k127_7232970_15 Integral membrane protein DUF92 - - - 0.0001163 49.0
PYH1_k127_7232970_2 Bacterial regulatory protein, Fis family - - - 9.627e-209 667.0
PYH1_k127_7232970_3 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 501.0
PYH1_k127_7232970_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 443.0
PYH1_k127_7232970_5 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 377.0
PYH1_k127_7232970_6 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
PYH1_k127_7232970_8 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000000000000000000000000000000002159 244.0
PYH1_k127_7232970_9 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000001217 220.0
PYH1_k127_7283278_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 458.0
PYH1_k127_7304292_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1304.0
PYH1_k127_7304292_1 PFAM Cytochrome c assembly protein K02198 - - 2.168e-301 936.0
PYH1_k127_7304292_10 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000000000000005188 165.0
PYH1_k127_7304292_11 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000008851 173.0
PYH1_k127_7304292_12 Bacterial-like globin K06886 - - 0.0000000000000000000000000000001346 131.0
PYH1_k127_7304292_13 - - - - 0.000000000000000000001582 102.0
PYH1_k127_7304292_14 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000004664 71.0
PYH1_k127_7304292_16 Protein of unknown function (DUF2934) - - - 0.000001504 53.0
PYH1_k127_7304292_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 463.0
PYH1_k127_7304292_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 439.0
PYH1_k127_7304292_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 444.0
PYH1_k127_7304292_5 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 421.0
PYH1_k127_7304292_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 384.0
PYH1_k127_7304292_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 361.0
PYH1_k127_7304292_8 cyclic nucleotide binding K13795 - - 0.00000000000000000000000000000000000000000000000000000000000001575 245.0
PYH1_k127_7304292_9 recA bacterial DNA recombination protein - - - 0.0000000000000000000000000000000000000000000000000000000001308 213.0
PYH1_k127_7354364_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 499.0
PYH1_k127_7354364_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 447.0
PYH1_k127_7354364_2 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 417.0
PYH1_k127_7354364_3 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 376.0
PYH1_k127_7354364_4 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000002573 241.0
PYH1_k127_7354364_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000005084 161.0
PYH1_k127_7354364_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000001575 120.0
PYH1_k127_7354364_8 Tfp pilus assembly protein FimV - - - 0.00000000000000001738 95.0
PYH1_k127_7379778_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1137.0
PYH1_k127_7379778_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 482.0
PYH1_k127_7379778_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000002992 213.0
PYH1_k127_7379778_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000001452 70.0
PYH1_k127_7379778_13 PD-(D/E)XK endonuclease - - - 0.00000001819 63.0
PYH1_k127_7379778_14 Protein of unknown function (DUF2621) - - - 0.0000005956 57.0
PYH1_k127_7379778_2 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 445.0
PYH1_k127_7379778_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 446.0
PYH1_k127_7379778_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 356.0
PYH1_k127_7379778_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 338.0
PYH1_k127_7379778_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 295.0
PYH1_k127_7379778_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 282.0
PYH1_k127_7379778_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002326 244.0
PYH1_k127_7379778_9 gluconolactonase activity K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000732 244.0
PYH1_k127_7404453_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 417.0
PYH1_k127_7404453_1 TOBE domain K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 341.0
PYH1_k127_7404453_10 TOBE domain - - - 0.000000000000000000000000000000000000000000000000001235 185.0
PYH1_k127_7404453_11 iron ion homeostasis K05349 - 3.2.1.21 0.00000000000000000001189 106.0
PYH1_k127_7404453_2 molybdate abc transporter K02018,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 315.0
PYH1_k127_7404453_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 307.0
PYH1_k127_7404453_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 294.0
PYH1_k127_7404453_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003979 282.0
PYH1_k127_7404453_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001453 276.0
PYH1_k127_7404453_7 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000462 279.0
PYH1_k127_7404453_8 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001639 250.0
PYH1_k127_7404453_9 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000001543 217.0
PYH1_k127_749045_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 567.0
PYH1_k127_749045_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 498.0
PYH1_k127_749045_2 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH1_k127_749045_4 - - - - 0.0000000000000000003652 91.0
PYH1_k127_749045_6 MacB-like periplasmic core domain K02004 - - 0.0000000001744 63.0
PYH1_k127_7558593_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 1.114e-196 618.0
PYH1_k127_7558593_1 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 376.0
PYH1_k127_7558593_2 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 377.0
PYH1_k127_7558593_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 289.0
PYH1_k127_7558593_4 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000004126 149.0
PYH1_k127_7558593_6 Tetratricopeptide repeat - - - 0.00000000000008787 83.0
PYH1_k127_7563629_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 465.0
PYH1_k127_7563629_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 282.0
PYH1_k127_7563629_2 - - - - 0.00000000000000000000000000000000000000000000000000251 186.0
PYH1_k127_7563629_3 antisigma factor binding K04749 - - 0.0000000000000000000001932 101.0
PYH1_k127_7570900_0 radical SAM domain protein K15045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 541.0
PYH1_k127_7570900_1 His Kinase A (phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 408.0
PYH1_k127_7570900_2 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 299.0
PYH1_k127_7570900_3 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000004077 216.0
PYH1_k127_7570900_4 peroxiredoxin activity K01607,K03469 - 3.1.26.4,4.1.1.44 0.000000000000000000000000000000000000000000000000000000001744 212.0
PYH1_k127_7570900_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000009647 167.0
PYH1_k127_7570900_6 4Fe-4S dicluster domain - - - 0.00000000000000000008763 90.0
PYH1_k127_7574677_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.611e-320 989.0
PYH1_k127_7574677_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 571.0
PYH1_k127_7574677_10 Belongs to the UPF0235 family K09131 - - 0.000000000000000001995 86.0
PYH1_k127_7574677_11 - - - - 0.00000000000000003796 89.0
PYH1_k127_7574677_2 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 535.0
PYH1_k127_7574677_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 492.0
PYH1_k127_7574677_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 440.0
PYH1_k127_7574677_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 427.0
PYH1_k127_7574677_6 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002615 263.0
PYH1_k127_7574677_7 - - - - 0.000000000000000000000000000000000000009668 159.0
PYH1_k127_7574677_8 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000001285 131.0
PYH1_k127_7574677_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000004543 114.0
PYH1_k127_7622746_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 549.0
PYH1_k127_7622746_1 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 504.0
PYH1_k127_7629321_0 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 535.0
PYH1_k127_7629321_1 Aminotransferase class-V K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 430.0
PYH1_k127_7629321_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 355.0
PYH1_k127_7629321_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 336.0
PYH1_k127_7629321_4 maltose O-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 333.0
PYH1_k127_7629321_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000002201 241.0
PYH1_k127_7629321_6 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000004434 207.0
PYH1_k127_7629321_7 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000001069 209.0
PYH1_k127_7629321_8 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000001499 139.0
PYH1_k127_7640527_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6e-240 753.0
PYH1_k127_7640527_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 457.0
PYH1_k127_7640527_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
PYH1_k127_7640527_3 - - - - 0.00000000000000000000000000000000000000000000000000000000004657 222.0
PYH1_k127_7640527_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000003111 205.0
PYH1_k127_7640527_5 - - - - 0.00000000000000000000000000000004862 133.0
PYH1_k127_7640527_6 - - - - 0.00000000000009328 81.0
PYH1_k127_7656931_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1106.0
PYH1_k127_7656931_1 YidE YbjL duplication domain protein K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 481.0
PYH1_k127_7656931_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007968 254.0
PYH1_k127_7656931_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000000000008568 79.0
PYH1_k127_7666729_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 548.0
PYH1_k127_7666729_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 387.0
PYH1_k127_7666729_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 323.0
PYH1_k127_7666729_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000005561 200.0
PYH1_k127_7684666_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1703.0
PYH1_k127_7684666_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.756e-287 893.0
PYH1_k127_7684666_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 422.0
PYH1_k127_7684666_11 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 412.0
PYH1_k127_7684666_12 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
PYH1_k127_7684666_13 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 345.0
PYH1_k127_7684666_14 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 312.0
PYH1_k127_7684666_15 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000003183 250.0
PYH1_k127_7684666_16 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001856 241.0
PYH1_k127_7684666_17 - - - - 0.00000000000000000000000000000000000000000000000000000000001325 211.0
PYH1_k127_7684666_18 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000000000000000000004633 209.0
PYH1_k127_7684666_2 Mur ligase middle domain K02558 - 6.3.2.45 5.208e-202 643.0
PYH1_k127_7684666_3 Aminotransferase class I and II - - - 4.219e-199 626.0
PYH1_k127_7684666_4 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 601.0
PYH1_k127_7684666_5 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 559.0
PYH1_k127_7684666_6 PFAM peptidase M61 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 475.0
PYH1_k127_7684666_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 458.0
PYH1_k127_7684666_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 449.0
PYH1_k127_7684666_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 434.0
PYH1_k127_7723450_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 367.0
PYH1_k127_7723450_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 359.0
PYH1_k127_7723450_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 358.0
PYH1_k127_7723450_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 339.0
PYH1_k127_7779228_0 Prolyl oligopeptidase - - - 1.442e-264 829.0
PYH1_k127_7779228_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 1.639e-203 674.0
PYH1_k127_7779228_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 497.0
PYH1_k127_7779228_3 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002561 273.0
PYH1_k127_7779228_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
PYH1_k127_7779228_5 Frataxin-like domain K06202 - - 0.000000000000000000000000000000000009552 138.0
PYH1_k127_7779228_6 iron ion homeostasis K05349 - 3.2.1.21 0.0000000000000000000000000008415 122.0
PYH1_k127_7779228_7 Beta-lactamase superfamily domain - - - 0.00000000000000000003454 100.0
PYH1_k127_7843106_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 293.0
PYH1_k127_7843106_1 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 286.0
PYH1_k127_7843106_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000001799 238.0
PYH1_k127_7843106_3 - - - - 0.000000000000000008072 94.0
PYH1_k127_7843106_4 ubiE/COQ5 methyltransferase family - - - 0.000000001007 68.0
PYH1_k127_7858820_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 7.33e-201 644.0
PYH1_k127_7858820_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 397.0
PYH1_k127_7858820_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004251 254.0
PYH1_k127_7858820_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000003507 121.0
PYH1_k127_7858820_4 - - - - 0.00000000000000000000000000006968 124.0
PYH1_k127_7858820_5 - - - - 0.0000000000000000003343 96.0
PYH1_k127_7861819_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1525.0
PYH1_k127_7861819_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1370.0
PYH1_k127_7861819_2 - - - - 0.00000000000000000000000000000118 128.0
PYH1_k127_7861819_3 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000009486 87.0
PYH1_k127_7868710_0 Protein of unknown function (DUF1343) - - - 1.827e-251 791.0
PYH1_k127_7868710_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 327.0
PYH1_k127_7868710_2 multi-organism process K03195 - - 0.000000000000000000000000000000000000000000000000494 181.0
PYH1_k127_7885465_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 557.0
PYH1_k127_7885465_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000001418 246.0
PYH1_k127_7885465_2 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000001474 237.0
PYH1_k127_7885465_3 carbon utilization K02664,K02665,K12280 - - 0.00000000000000000000000000000000000000000000000000000001631 204.0
PYH1_k127_7885465_4 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000001477 188.0
PYH1_k127_7885465_6 Helix-turn-helix domain - - - 0.000000000000000000000000000000009565 130.0
PYH1_k127_7960952_0 Carboxypeptidase regulatory-like domain - - - 1.112e-305 962.0
PYH1_k127_7960952_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 509.0
PYH1_k127_7965499_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 500.0
PYH1_k127_7965499_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 441.0
PYH1_k127_7965499_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 334.0
PYH1_k127_7965499_3 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 297.0
PYH1_k127_7965499_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
PYH1_k127_7965499_5 glutamate dehydrogenase [NAD(P)+] activity K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001155 294.0
PYH1_k127_7965499_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004011 243.0
PYH1_k127_7965499_7 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000003458 108.0
PYH1_k127_8013120_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 574.0
PYH1_k127_8013120_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 416.0
PYH1_k127_8013120_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 391.0
PYH1_k127_8013120_3 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 306.0
PYH1_k127_8013120_4 Heavy-metal resistance - - - 0.000000000000000000001078 102.0
PYH1_k127_8075864_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.262e-214 676.0
PYH1_k127_8075864_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 566.0
PYH1_k127_8075864_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 537.0
PYH1_k127_8075864_3 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 507.0
PYH1_k127_8075864_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 452.0
PYH1_k127_8075864_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 364.0
PYH1_k127_8075864_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 298.0
PYH1_k127_8075864_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001375 233.0
PYH1_k127_8075864_8 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000001008 198.0
PYH1_k127_8075864_9 - - - - 0.000001181 53.0
PYH1_k127_8086809_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1134.0
PYH1_k127_8094062_0 Permease, YjgP YjgQ - - - 1.52e-295 925.0
PYH1_k127_8094062_1 Glycosyl hydrolase family 57 - - - 1.711e-291 912.0
PYH1_k127_8094062_10 Tfp pilus assembly protein FimV - - - 0.000000000007767 74.0
PYH1_k127_8094062_11 peroxiredoxin activity K03564 - 1.11.1.15 0.0000001174 57.0
PYH1_k127_8094062_12 Redoxin - - - 0.00006198 49.0
PYH1_k127_8094062_13 Belongs to the peptidase M28 family K05994 - 3.4.11.10 0.0002681 54.0
PYH1_k127_8094062_2 ABC transporter, transmembrane K18889 - - 3.92e-262 823.0
PYH1_k127_8094062_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.993e-246 777.0
PYH1_k127_8094062_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.938e-222 695.0
PYH1_k127_8094062_5 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 386.0
PYH1_k127_8094062_6 TIGRFAM TonB K03832 - - 0.000000000000000000000000000000000000000000000000000001417 200.0
PYH1_k127_8094062_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001154 182.0
PYH1_k127_8094062_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000003138 183.0
PYH1_k127_8094062_9 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000001391 80.0
PYH1_k127_8096068_0 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 488.0
PYH1_k127_8096068_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 346.0
PYH1_k127_8096068_2 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 335.0
PYH1_k127_8096068_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
PYH1_k127_8096068_4 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000003564 180.0
PYH1_k127_8096068_6 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.0000009963 51.0
PYH1_k127_8097843_0 Cupin 2, conserved barrel domain protein - - - 0.000000002592 67.0
PYH1_k127_8097843_1 Cupin domain - - - 0.000000003302 67.0
PYH1_k127_8116249_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000004412 212.0
PYH1_k127_8116249_1 - - - - 0.000000000000000000000000000000000000000000008612 183.0
PYH1_k127_8116249_2 Protein tyrosine kinase - - - 0.00000000000000000000000007768 112.0
PYH1_k127_8119120_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 395.0
PYH1_k127_8119120_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000008171 186.0
PYH1_k127_8119120_2 cyclic nucleotide binding K10914 - - 0.000000000000000007164 89.0
PYH1_k127_8119120_3 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000007915 72.0
PYH1_k127_8119120_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000001756 69.0
PYH1_k127_8119120_5 - - - - 0.000005602 56.0
PYH1_k127_8122740_0 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 501.0
PYH1_k127_8354435_0 Two component signalling adaptor domain K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 548.0
PYH1_k127_8354435_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 336.0
PYH1_k127_8354435_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000006932 180.0
PYH1_k127_8354435_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000348 159.0
PYH1_k127_8354435_4 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000003242 136.0
PYH1_k127_8354435_5 PhoQ Sensor - - - 0.000000000000000000000000208 108.0
PYH1_k127_8354435_6 chemotaxis signal transduction protein K03408 - - 0.0000000000000006955 87.0
PYH1_k127_855483_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 570.0
PYH1_k127_855483_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 476.0
PYH1_k127_855483_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 472.0
PYH1_k127_855483_3 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 430.0
PYH1_k127_855483_4 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 419.0
PYH1_k127_855483_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 314.0
PYH1_k127_855483_6 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009769 274.0
PYH1_k127_855483_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009386 266.0
PYH1_k127_855483_8 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000006835 167.0
PYH1_k127_855483_9 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000981 129.0
PYH1_k127_858994_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.228e-241 748.0
PYH1_k127_858994_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.667e-231 721.0
PYH1_k127_858994_10 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000316 204.0
PYH1_k127_858994_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000005239 169.0
PYH1_k127_858994_12 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000000000000214 170.0
PYH1_k127_858994_13 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase - - - 0.0000000001135 68.0
PYH1_k127_858994_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000001287 57.0
PYH1_k127_858994_16 - - - - 0.0005763 44.0
PYH1_k127_858994_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 489.0
PYH1_k127_858994_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 377.0
PYH1_k127_858994_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 374.0
PYH1_k127_858994_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 355.0
PYH1_k127_858994_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
PYH1_k127_858994_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 321.0
PYH1_k127_858994_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000000000004523 216.0
PYH1_k127_858994_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000001986 226.0
PYH1_k127_862148_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 1.134e-202 643.0
PYH1_k127_862148_1 Protein involved in outer membrane biogenesis K07289,K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 484.0
PYH1_k127_862148_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000001018 59.0
PYH1_k127_862148_2 Gas vesicle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 332.0
PYH1_k127_862148_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 295.0
PYH1_k127_862148_4 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000006618 218.0
PYH1_k127_862148_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000001388 159.0
PYH1_k127_862148_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000001281 164.0
PYH1_k127_862148_8 His Kinase A (phosphoacceptor - - - 0.0000000000000000001877 102.0
PYH1_k127_862148_9 - - - - 0.0000000000000004232 87.0
PYH1_k127_886070_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.077e-224 699.0
PYH1_k127_886070_1 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 355.0
PYH1_k127_886070_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 285.0
PYH1_k127_886070_3 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 283.0
PYH1_k127_886070_4 stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000003796 162.0
PYH1_k127_886070_5 dinuclear metal center protein, YbgI - - - 0.000000000000000000000000000000000000000000364 159.0
PYH1_k127_935032_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1189.0
PYH1_k127_935032_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 6.588e-241 770.0
PYH1_k127_935032_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.702e-239 750.0
PYH1_k127_935032_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 602.0
PYH1_k127_935032_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 509.0
PYH1_k127_935032_5 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000129 193.0
PYH1_k127_935032_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000001371 175.0
PYH1_k127_935032_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000001586 148.0
PYH1_k127_937749_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.417e-225 703.0
PYH1_k127_937749_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 306.0
PYH1_k127_937749_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000005589 164.0
PYH1_k127_937749_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000003395 160.0
PYH1_k127_937749_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000005873 145.0
PYH1_k127_937749_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000001728 147.0
PYH1_k127_937749_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000001185 140.0
PYH1_k127_937749_15 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000002795 94.0
PYH1_k127_937749_16 Ribosomal protein L30 K02907 - - 0.00000000000000004486 90.0
PYH1_k127_937749_17 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000004978 69.0
PYH1_k127_937749_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000155 271.0
PYH1_k127_937749_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000362 262.0
PYH1_k127_937749_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006269 255.0
PYH1_k127_937749_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000007658 226.0
PYH1_k127_937749_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000000645 224.0
PYH1_k127_937749_7 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000000297 205.0
PYH1_k127_937749_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000521 203.0
PYH1_k127_937749_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000002057 169.0
PYH1_k127_990933_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.285e-229 723.0
PYH1_k127_990933_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 571.0
PYH1_k127_990933_10 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000002035 185.0
PYH1_k127_990933_11 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000009202 119.0
PYH1_k127_990933_12 Radical SAM - - - 0.000000000000000000001581 94.0
PYH1_k127_990933_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000005709 85.0
PYH1_k127_990933_14 6-phosphogluconolactonase activity K07404 - 3.1.1.31 0.0000000006057 72.0
PYH1_k127_990933_15 - - - - 0.000004869 49.0
PYH1_k127_990933_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 544.0
PYH1_k127_990933_3 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 481.0
PYH1_k127_990933_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 411.0
PYH1_k127_990933_5 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 422.0
PYH1_k127_990933_6 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 338.0
PYH1_k127_990933_7 Bacterial regulatory helix-turn-helix protein, lysR family K03576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 293.0
PYH1_k127_990933_8 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000131 259.0
PYH1_k127_990933_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000001367 194.0