Overview

ID MAG03167
Name PYH1_bin.66
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum WOR-3
Class WOR-3
Order SM23-42
Family
Genus
Species
Assembly information
Completeness (%) 74.74
Contamination (%) 1.59
GC content (%) 57.0
N50 (bp) 4,421
Genome size (bp) 1,556,020

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1436

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1004389_0 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 314.0
PYH1_k127_1004389_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 323.0
PYH1_k127_1024004_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 566.0
PYH1_k127_1024004_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000004597 58.0
PYH1_k127_1031744_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 411.0
PYH1_k127_1031744_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 319.0
PYH1_k127_1031744_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000002018 134.0
PYH1_k127_1031744_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000004898 103.0
PYH1_k127_1050611_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000003833 228.0
PYH1_k127_1050611_1 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000003633 177.0
PYH1_k127_1050611_2 Rubrerythrin - - - 0.000000000000000000000000000000000252 139.0
PYH1_k127_1050611_3 Metallo-beta-lactamase superfamily - - - 0.00000000000008041 72.0
PYH1_k127_1074483_0 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 3.4e-238 746.0
PYH1_k127_1074483_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 315.0
PYH1_k127_1074483_2 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000008657 226.0
PYH1_k127_1074483_3 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000004676 214.0
PYH1_k127_1074483_4 AMP binding - - - 0.0000000000000000000000000000000000000000000000000001985 194.0
PYH1_k127_1074483_5 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000006158 135.0
PYH1_k127_1074483_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000002745 131.0
PYH1_k127_1074483_7 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000009353 111.0
PYH1_k127_1074483_8 PBP superfamily domain K02040 - - 0.00001187 53.0
PYH1_k127_107630_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 405.0
PYH1_k127_107630_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 338.0
PYH1_k127_107630_2 diguanylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000004253 223.0
PYH1_k127_107630_3 peroxiredoxin activity - - - 0.00000001937 59.0
PYH1_k127_107630_4 ASPIC and UnbV - - - 0.0005555 44.0
PYH1_k127_1091896_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 359.0
PYH1_k127_1104556_0 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 471.0
PYH1_k127_1104556_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134,K00150 - 1.2.1.12,1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
PYH1_k127_1104556_2 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000001719 108.0
PYH1_k127_110501_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 348.0
PYH1_k127_1115610_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 495.0
PYH1_k127_1124220_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 373.0
PYH1_k127_1124220_1 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation K16898 - 3.6.4.12 0.00000000000000000000000001012 113.0
PYH1_k127_1137479_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 354.0
PYH1_k127_1137479_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000009174 215.0
PYH1_k127_1137479_2 Thioesterase superfamily - - - 0.0000000000000000000000003117 109.0
PYH1_k127_1137479_3 extracellular matrix structural constituent - - - 0.000000000003404 76.0
PYH1_k127_1137479_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000242 72.0
PYH1_k127_1152357_0 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000005472 205.0
PYH1_k127_1152357_1 type I secretion outer membrane protein, TolC K12340 GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351 - 0.0001189 52.0
PYH1_k127_1199979_0 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 305.0
PYH1_k127_1199979_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
PYH1_k127_1199979_2 Peptidase S24-like K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000007853 184.0
PYH1_k127_1199979_3 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000085 180.0
PYH1_k127_1202208_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 404.0
PYH1_k127_1202208_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000378 245.0
PYH1_k127_1202208_2 ATP:guanido phosphotransferase, C-terminal catalytic domain K00933,K00934,K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1,2.7.3.2,2.7.3.3 0.00000000000000000000000000000000000000000000006011 174.0
PYH1_k127_1202208_3 thioesterase - - - 0.00004342 47.0
PYH1_k127_122334_0 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 415.0
PYH1_k127_122334_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 399.0
PYH1_k127_122334_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 374.0
PYH1_k127_122334_3 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000006844 215.0
PYH1_k127_122334_4 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000007906 179.0
PYH1_k127_122334_5 Protein of unknown function (DUF1624) - - - 0.0000000000000000000003334 109.0
PYH1_k127_122334_6 PFAM PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000261 89.0
PYH1_k127_122334_7 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.00002164 49.0
PYH1_k127_1242573_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 432.0
PYH1_k127_1242573_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 379.0
PYH1_k127_1242573_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000007116 238.0
PYH1_k127_1242573_3 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000002374 104.0
PYH1_k127_1242573_4 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001415 100.0
PYH1_k127_1242573_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000009715 85.0
PYH1_k127_1244460_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000003237 224.0
PYH1_k127_1244460_1 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000003745 98.0
PYH1_k127_1244460_2 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000895 92.0
PYH1_k127_1244460_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000002439 60.0
PYH1_k127_1264439_0 PFAM NADH Ubiquinone plastoquinone (complex I) K00341,K05568,K12139,K14086 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 370.0
PYH1_k127_1264439_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000701 213.0
PYH1_k127_1264439_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000006756 61.0
PYH1_k127_1265657_0 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001526 95.0
PYH1_k127_1274717_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000016 252.0
PYH1_k127_1274717_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000001227 101.0
PYH1_k127_1274717_2 domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000005891 92.0
PYH1_k127_1274717_3 Protein of unknown function (DUF503) K09764 - - 0.00000000000000004417 84.0
PYH1_k127_1283916_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007036 305.0
PYH1_k127_1283916_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009174 278.0
PYH1_k127_1283916_2 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000004069 196.0
PYH1_k127_1283916_3 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000001202 145.0
PYH1_k127_1334671_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 305.0
PYH1_k127_1345888_0 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004144 247.0
PYH1_k127_1345888_1 diguanylate cyclase - - - 0.000000000000000000000000000006471 139.0
PYH1_k127_1345888_2 NHL repeat - - - 0.00000000000000000000000983 111.0
PYH1_k127_1345888_3 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000007423 96.0
PYH1_k127_1345888_4 TfoX N-terminal domain - - - 0.00000000000000003861 85.0
PYH1_k127_1345888_5 Parallel beta-helix repeats - - - 0.00000007353 64.0
PYH1_k127_1345888_6 Peptidase family C25 - - - 0.000003001 59.0
PYH1_k127_1359169_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 573.0
PYH1_k127_1359169_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000003836 184.0
PYH1_k127_1368182_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 507.0
PYH1_k127_1368182_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 457.0
PYH1_k127_1368182_2 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000007735 194.0
PYH1_k127_1368182_3 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000002004 122.0
PYH1_k127_1368182_4 Surface antigen - - - 0.000000000000000002314 98.0
PYH1_k127_1384902_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 270.0
PYH1_k127_1384902_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000002152 181.0
PYH1_k127_1384902_2 Protein of unknown function (DUF3494) - - - 0.0000000000000000000119 109.0
PYH1_k127_1384902_3 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000003798 75.0
PYH1_k127_1384902_4 Acyl-protein thioesterase. Source PGD - - - 0.00002564 52.0
PYH1_k127_1411076_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 464.0
PYH1_k127_1411076_1 Best Blastp hit gi 6685602 sp Q57957 KORB_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB (2-KETOGLUTARATE OXIDOREDUCTASE BETA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi 2129229 pir A64367 pyruvate synthase (EC 1.2.7.1) beta chain - Methanococcus jannaschii gi 1591241 gb AAB98531.1 '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB) Methanococcus jannaschii ', score K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 340.0
PYH1_k127_1411076_2 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 346.0
PYH1_k127_1411076_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000001142 226.0
PYH1_k127_1411076_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000003183 90.0
PYH1_k127_141592_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 364.0
PYH1_k127_141592_1 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000001153 196.0
PYH1_k127_1419510_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 404.0
PYH1_k127_1419510_1 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000001977 201.0
PYH1_k127_1419510_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000001234 109.0
PYH1_k127_145524_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.013e-304 955.0
PYH1_k127_145524_1 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000001536 205.0
PYH1_k127_145524_2 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000000001149 78.0
PYH1_k127_1490591_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 320.0
PYH1_k127_1490591_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595,K06883 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002091 271.0
PYH1_k127_1490591_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001588 224.0
PYH1_k127_1546634_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000001396 159.0
PYH1_k127_1546634_1 PFAM Methylated-DNA- protein -cysteine K07443 - - 0.0000000000000000000000000000005887 127.0
PYH1_k127_1577040_0 Two component regulator propeller K19693 - - 0.0003588 54.0
PYH1_k127_1588337_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 340.0
PYH1_k127_1588337_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 294.0
PYH1_k127_1588337_2 Psort location CytoplasmicMembrane, score K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000106 263.0
PYH1_k127_1588337_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002073 277.0
PYH1_k127_1588337_4 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000002948 191.0
PYH1_k127_1588337_5 peptidase activity, acting on L-amino acid peptides K01448,K07260,K09955,K13276 GO:0005575,GO:0005576 3.4.17.14,3.5.1.28 0.0000000008792 68.0
PYH1_k127_1598053_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000008693 248.0
PYH1_k127_1666966_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007288 284.0
PYH1_k127_1666966_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000001366 164.0
PYH1_k127_1666966_2 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000002653 179.0
PYH1_k127_1666966_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000005036 56.0
PYH1_k127_1731156_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 398.0
PYH1_k127_1731156_1 phosphatase activity K07025,K08723 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000321 222.0
PYH1_k127_1731156_2 Carbohydrate family 9 binding domain-like - - - 0.00000000000000004864 93.0
PYH1_k127_1731156_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000003107 74.0
PYH1_k127_1760405_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 614.0
PYH1_k127_1760405_1 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 322.0
PYH1_k127_1760405_2 HD domain - - - 0.00000000000000000000000000000000000000000000000002189 196.0
PYH1_k127_1760405_3 manganese ion transmembrane transporter activity - - - 0.000009263 48.0
PYH1_k127_176888_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 384.0
PYH1_k127_176888_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007893 252.0
PYH1_k127_176888_2 - - - - 0.00000000000000000000000000000004862 133.0
PYH1_k127_176888_3 Tetratricopeptide repeat - - - 0.0000000000000001708 87.0
PYH1_k127_176888_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000007018 51.0
PYH1_k127_176888_5 Transposase IS200 like K07491 - - 0.000144 50.0
PYH1_k127_1867636_0 Glycoside hydrolase family 24 - - - 0.000000000000000000000000000003749 139.0
PYH1_k127_1867636_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000002213 55.0
PYH1_k127_190629_0 DNA topoisomerase II activity K02469 - 5.99.1.3 5.766e-305 954.0
PYH1_k127_190629_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003552 222.0
PYH1_k127_190629_2 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000002093 206.0
PYH1_k127_190629_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000006882 186.0
PYH1_k127_190629_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.0000000000000000000000000006763 128.0
PYH1_k127_1937343_0 hydrogenase large subunit K14126 - 1.8.98.5 3.616e-222 699.0
PYH1_k127_1937343_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 502.0
PYH1_k127_1937343_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 513.0
PYH1_k127_1937343_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 293.0
PYH1_k127_1937343_4 Glycine cleavage H-protein K02437 - - 0.0000000000000000000000000000000000002434 145.0
PYH1_k127_1937434_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 9.197e-260 816.0
PYH1_k127_1937434_1 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 563.0
PYH1_k127_1937434_2 ABC transporter K10112,K11072,K17324 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 400.0
PYH1_k127_1937434_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 324.0
PYH1_k127_1937434_4 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000002414 263.0
PYH1_k127_1937434_5 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000003067 205.0
PYH1_k127_1937434_6 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000004313 166.0
PYH1_k127_1937434_7 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000002125 114.0
PYH1_k127_1937434_8 cellulose binding K00505 - 1.14.18.1 0.00000000000008091 83.0
PYH1_k127_1937434_9 xylan catabolic process K01179,K03932 - 3.2.1.4 0.0000005044 63.0
PYH1_k127_1942841_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 364.0
PYH1_k127_1942841_1 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000000000000000000003546 171.0
PYH1_k127_1942841_2 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000003679 157.0
PYH1_k127_1942841_3 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000003038 157.0
PYH1_k127_1942841_4 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000002989 100.0
PYH1_k127_1942841_5 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000004264 67.0
PYH1_k127_1942841_6 Subtilase family - - - 0.000000203 64.0
PYH1_k127_1946457_0 aminopeptidase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 358.0
PYH1_k127_1946457_1 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 323.0
PYH1_k127_1946457_2 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 314.0
PYH1_k127_1946457_3 4Fe-4S dicluster domain - - - 0.000000000000000000509 88.0
PYH1_k127_1946457_4 PFAM alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.000000000000000009746 98.0
PYH1_k127_1946457_5 Peptidase family M1 domain K01256 - 3.4.11.2 0.0000946 50.0
PYH1_k127_1957513_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006667 247.0
PYH1_k127_1961052_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 2.303e-313 998.0
PYH1_k127_1961052_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 451.0
PYH1_k127_1961052_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 403.0
PYH1_k127_1961052_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 312.0
PYH1_k127_1961052_4 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000002586 141.0
PYH1_k127_1961052_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000001325 130.0
PYH1_k127_1961052_6 Exopolysaccharide biosynthesis protein YbjH - - - 0.00000000000000000000000000002869 125.0
PYH1_k127_1961052_7 OsmC-like protein K07397 - - 0.00000000000000000000000000003905 121.0
PYH1_k127_1961052_8 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01083,K06131,K06915 - 3.1.3.8 0.0000000000001621 82.0
PYH1_k127_1961052_9 Protein conserved in bacteria - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000001025 63.0
PYH1_k127_1963077_0 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 450.0
PYH1_k127_1963077_1 metallopeptidase activity K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000597 247.0
PYH1_k127_1963077_2 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000489 180.0
PYH1_k127_1963077_3 - - - - 0.00000000000000000004813 100.0
PYH1_k127_2000885_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000001415 180.0
PYH1_k127_2000885_1 histidine kinase DNA gyrase B - - - 0.0001673 54.0
PYH1_k127_2015138_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000002325 229.0
PYH1_k127_2015138_1 Pilus assembly protein, PilO K02664 - - 0.0000000000000000001413 95.0
PYH1_k127_2015138_3 Fimbrial assembly protein (PilN) - - - 0.0000002885 58.0
PYH1_k127_2043529_0 Belongs to the GARS family K01945,K01952 - 6.3.4.13,6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 435.0
PYH1_k127_2043529_1 Belongs to the SUA5 family K01104,K01808,K07566,K20201 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.0000000000000000000000000000000000000000004071 170.0
PYH1_k127_2043529_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000004955 140.0
PYH1_k127_2063577_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 403.0
PYH1_k127_2063577_1 Belongs to the UPF0434 family K09791 - - 0.00000000001368 70.0
PYH1_k127_2064190_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000003063 215.0
PYH1_k127_2064190_1 sporulation resulting in formation of a cellular spore K06381 - - 0.00000000000000000000000000000000000000000000000000001468 200.0
PYH1_k127_2064190_2 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000000001742 115.0
PYH1_k127_2064190_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000001251 100.0
PYH1_k127_2096891_0 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 395.0
PYH1_k127_2096891_1 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 324.0
PYH1_k127_2096891_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001027 252.0
PYH1_k127_2109840_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 510.0
PYH1_k127_2109840_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 441.0
PYH1_k127_2109840_2 Major facilitator superfamily - - - 0.0000001935 64.0
PYH1_k127_2125106_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002188 259.0
PYH1_k127_2125106_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000003845 183.0
PYH1_k127_2125106_2 MFS/sugar transport protein K08177 - - 0.000000000000000000000000000000000000000008793 157.0
PYH1_k127_2125106_3 PFAM Collagen triple helix - - - 0.0000063 57.0
PYH1_k127_2136782_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.794e-268 844.0
PYH1_k127_2136782_1 Phosphoribulokinase uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000004389 248.0
PYH1_k127_2136782_2 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000006874 153.0
PYH1_k127_2171331_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 374.0
PYH1_k127_218440_0 2 iron, 2 sulfur cluster binding K00528,K02823,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003613 261.0
PYH1_k127_218440_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124,K21308 - - 0.00000000000000000000000003401 113.0
PYH1_k127_218440_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0000000000000008665 91.0
PYH1_k127_218440_3 quinone binding K00337 - 1.6.5.3 0.0000000000001622 74.0
PYH1_k127_2187235_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 368.0
PYH1_k127_2191668_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 495.0
PYH1_k127_2191668_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 379.0
PYH1_k127_2191668_2 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
PYH1_k127_2191668_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006158 273.0
PYH1_k127_2191668_4 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000009272 150.0
PYH1_k127_2191668_5 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000004886 120.0
PYH1_k127_2191668_6 HEAT repeats - - - 0.0000001146 59.0
PYH1_k127_21933_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 347.0
PYH1_k127_21933_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002272 258.0
PYH1_k127_21933_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007479 79.0
PYH1_k127_21933_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001354 83.0
PYH1_k127_21933_12 Ribosomal L29 protein K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000034 73.0
PYH1_k127_21933_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000001189 242.0
PYH1_k127_21933_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000005802 195.0
PYH1_k127_21933_4 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000009523 196.0
PYH1_k127_21933_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000008594 141.0
PYH1_k127_21933_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000008244 138.0
PYH1_k127_21933_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000005126 110.0
PYH1_k127_21933_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000003153 93.0
PYH1_k127_21933_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000005736 89.0
PYH1_k127_2249859_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 293.0
PYH1_k127_2249859_1 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.000000000000000000000000000000000000000000006672 174.0
PYH1_k127_2249859_2 Polymer-forming cytoskeletal - - - 0.0000000000000004594 82.0
PYH1_k127_2262140_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000001658 235.0
PYH1_k127_2262140_1 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000001152 220.0
PYH1_k127_2262140_2 D-glucuronyl C5-epimerase C-terminus - - - 0.0000000000000000000000000000000000004393 151.0
PYH1_k127_2262140_3 pyruvate formate lyase activating K04070 - 1.97.1.4 0.00000000000000000000000004563 108.0
PYH1_k127_2262140_4 Polysaccharide biosynthesis protein - - - 0.0001944 45.0
PYH1_k127_2325455_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 3.862e-238 743.0
PYH1_k127_2325455_1 PFAM Sodium sulphate symporter K14445 - - 0.0000000000000000000000000000000000004649 143.0
PYH1_k127_2325455_2 COG0662 Mannose-6-phosphate isomerase - - - 0.0000000000000000000036 96.0
PYH1_k127_232803_0 Phosphoribosyl-AMP cyclohydrolase K01496,K01497,K01814,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 445.0
PYH1_k127_232803_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 367.0
PYH1_k127_233825_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 470.0
PYH1_k127_233825_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 306.0
PYH1_k127_233825_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 301.0
PYH1_k127_233825_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.00000000000000000000000000000000000000000000000000001643 211.0
PYH1_k127_233825_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000008181 125.0
PYH1_k127_233825_5 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000005802 98.0
PYH1_k127_2342323_0 PFAM homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 529.0
PYH1_k127_2342323_1 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000008225 117.0
PYH1_k127_2367327_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 523.0
PYH1_k127_2367327_1 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000001486 106.0
PYH1_k127_2367327_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.00000000000000004642 87.0
PYH1_k127_2381975_0 virulence plasmid 65kDa B protein - - - 9.789e-242 778.0
PYH1_k127_2395827_1 radical SAM domain protein K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007152 273.0
PYH1_k127_2395827_2 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.0000000000000000000000000000000000000000001059 165.0
PYH1_k127_2469371_0 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 307.0
PYH1_k127_2469371_1 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000007001 157.0
PYH1_k127_2469371_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000005589 76.0
PYH1_k127_2482695_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000006162 240.0
PYH1_k127_2482695_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000336 244.0
PYH1_k127_2482695_2 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000008664 162.0
PYH1_k127_2482695_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000007768 144.0
PYH1_k127_2482695_4 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000001533 76.0
PYH1_k127_2544105_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 608.0
PYH1_k127_2544105_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 586.0
PYH1_k127_2544105_2 PFAM NADH Ubiquinone plastoquinone (complex I) K00341,K05568,K12139,K14086 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001204 264.0
PYH1_k127_2544105_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000006484 220.0
PYH1_k127_2544105_4 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000002833 101.0
PYH1_k127_2609321_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 492.0
PYH1_k127_2609321_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000003148 170.0
PYH1_k127_2609321_2 rRNA binding K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.00000000000000000000000000000000000000004068 158.0
PYH1_k127_2609321_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000007006 148.0
PYH1_k127_2609321_4 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000001038 149.0
PYH1_k127_2609321_5 diguanylate cyclase - - - 0.0000000000000000000000001234 110.0
PYH1_k127_2609321_6 Ribosomal protein L30 K02907 - - 0.0000000000005744 72.0
PYH1_k127_2612468_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 600.0
PYH1_k127_2612468_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 381.0
PYH1_k127_2612468_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 335.0
PYH1_k127_2612468_3 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001616 265.0
PYH1_k127_2612468_4 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.000000000000000000000000000000002313 137.0
PYH1_k127_2612468_5 PaaX-like protein K02616 - - 0.0000000000000001481 90.0
PYH1_k127_2612468_6 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000002172 72.0
PYH1_k127_2617660_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004762 265.0
PYH1_k127_2617660_1 cellulose binding - - - 0.00000000007463 72.0
PYH1_k127_2617660_2 domain protein K07004,K09955,K20276 - - 0.0000000001344 72.0
PYH1_k127_2625918_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 374.0
PYH1_k127_2625918_1 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000001329 197.0
PYH1_k127_2625918_2 cob(I)yrinic acid a,c-diamide adenosyltransferase K19221 - 2.5.1.17 0.0008989 42.0
PYH1_k127_2652028_0 PglZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 404.0
PYH1_k127_2652028_1 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000439 248.0
PYH1_k127_2652028_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000001968 233.0
PYH1_k127_2652028_3 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000003397 131.0
PYH1_k127_2652028_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000931 71.0
PYH1_k127_2654402_0 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000000000005839 208.0
PYH1_k127_2654402_1 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000001311 180.0
PYH1_k127_2661502_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 333.0
PYH1_k127_2661502_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001062 268.0
PYH1_k127_2661502_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009699 271.0
PYH1_k127_2661502_3 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000000000000000000000000007396 203.0
PYH1_k127_2661502_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000001903 186.0
PYH1_k127_2661502_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000006682 129.0
PYH1_k127_2661502_6 Acylphosphatase - - - 0.0000000000000000000000000001425 117.0
PYH1_k127_2681434_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 394.0
PYH1_k127_2681434_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002387 270.0
PYH1_k127_2681434_2 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000006451 85.0
PYH1_k127_2681434_3 Subtilase family K17734 - - 0.00000000000000009118 91.0
PYH1_k127_2681434_4 Peptidase, M23 K21472 - - 0.00001266 58.0
PYH1_k127_2717639_0 MutL protein K00854 - 2.7.1.17 2.78e-263 823.0
PYH1_k127_2717639_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 604.0
PYH1_k127_2717639_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000003731 124.0
PYH1_k127_2717639_3 - - - - 0.00000000000000000000000173 104.0
PYH1_k127_2717639_4 - - - - 0.00000000004303 69.0
PYH1_k127_2719334_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 4.607e-271 851.0
PYH1_k127_2719334_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 499.0
PYH1_k127_2719334_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 344.0
PYH1_k127_2719334_3 Radical SAM domain protein K22227 - - 0.000000000000000000000000000001862 122.0
PYH1_k127_2719334_4 - - - - 0.0000000000000000000000000001411 128.0
PYH1_k127_2719334_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000002101 104.0
PYH1_k127_2719878_0 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 535.0
PYH1_k127_2731325_0 DEAD H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 333.0
PYH1_k127_2731325_1 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000004822 172.0
PYH1_k127_2731325_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000003851 136.0
PYH1_k127_2732260_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004364 302.0
PYH1_k127_2732260_1 diguanylate cyclase - - - 0.00000000001195 79.0
PYH1_k127_2732260_2 - - - - 0.0004557 49.0
PYH1_k127_2766413_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005112 276.0
PYH1_k127_2766413_1 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 287.0
PYH1_k127_2766413_2 sequence-specific DNA binding - - - 0.00000000002599 66.0
PYH1_k127_2768729_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004058 207.0
PYH1_k127_2768729_1 PHP domain K07053 - 3.1.3.97 0.000000000000000000001682 96.0
PYH1_k127_2768729_2 antibiotic catabolic process - - - 0.00005983 53.0
PYH1_k127_2772289_0 Evidence 5 No homology to any previously reported sequences K17713 - - 0.0000000000000000000000000000000000000000000001784 190.0
PYH1_k127_2793683_0 Protease prsW family - - - 0.00000000000000000000000000000008196 142.0
PYH1_k127_2793683_2 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0001269 48.0
PYH1_k127_2797976_0 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004386 254.0
PYH1_k127_2797976_1 PQQ enzyme repeat - - - 0.00000000000000000000000004739 123.0
PYH1_k127_2797976_2 amine dehydrogenase activity - - - 0.0002034 52.0
PYH1_k127_2836569_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1057.0
PYH1_k127_2836569_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009991 234.0
PYH1_k127_2836569_2 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000001013 176.0
PYH1_k127_2836569_3 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.0000000000000000000000006944 106.0
PYH1_k127_2915360_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 433.0
PYH1_k127_2915360_1 saccharopine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000002514 172.0
PYH1_k127_2921105_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 422.0
PYH1_k127_2921105_1 Belongs to the UbiD family - - - 0.0000000000000000000000000000000000182 139.0
PYH1_k127_2921225_0 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000007559 176.0
PYH1_k127_2921225_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000003498 128.0
PYH1_k127_2921225_2 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000006827 95.0
PYH1_k127_2930120_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
PYH1_k127_2930120_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000003586 161.0
PYH1_k127_2940238_0 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000571 288.0
PYH1_k127_3012493_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008261 260.0
PYH1_k127_3012493_1 spore germination K03298 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008858 261.0
PYH1_k127_301318_0 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 345.0
PYH1_k127_301318_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000576 230.0
PYH1_k127_301318_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000003401 204.0
PYH1_k127_301318_4 R3H domain protein K06346 - - 0.000000000000000000002599 101.0
PYH1_k127_301318_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002421 93.0
PYH1_k127_301318_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000008812 69.0
PYH1_k127_301318_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000006934 53.0
PYH1_k127_3016318_0 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004115 285.0
PYH1_k127_3016318_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000003651 78.0
PYH1_k127_3016318_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000231 64.0
PYH1_k127_3016318_3 Anti-sigma-K factor rskA - - - 0.00001807 54.0
PYH1_k127_3024782_0 carboxylase, biotin carboxylase K01961,K01965,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 389.0
PYH1_k127_3024782_1 Biotin-requiring enzyme - - - 0.0000000000000000000000000001687 121.0
PYH1_k127_3029085_0 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000375 231.0
PYH1_k127_3029085_1 Bacterial transcriptional activator domain - - - 0.0000000001378 75.0
PYH1_k127_3029085_2 regulatory protein LuxR K03556 - - 0.000002211 61.0
PYH1_k127_3048555_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 2.459e-234 733.0
PYH1_k127_3048555_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005936 259.0
PYH1_k127_3048555_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000522 251.0
PYH1_k127_3048555_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000002787 195.0
PYH1_k127_3048555_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000001382 193.0
PYH1_k127_3048555_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000002741 164.0
PYH1_k127_3048555_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000007082 126.0
PYH1_k127_3048555_7 - - - - 0.000000001382 66.0
PYH1_k127_3052525_0 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 453.0
PYH1_k127_3052525_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K02945,K03527,K03977,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009240,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042380,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046490,GO:0046939,GO:0046940,GO:0048037,GO:0050145,GO:0051186,GO:0051188,GO:0051536,GO:0051538,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.4.25,6.3.2.1 0.000000000000000000000000000000000000000000000000000281 192.0
PYH1_k127_3052525_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000001655 136.0
PYH1_k127_3052525_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000003223 51.0
PYH1_k127_3071914_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 7.391e-213 669.0
PYH1_k127_3071914_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000112 222.0
PYH1_k127_3071914_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000003542 113.0
PYH1_k127_3071914_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000009691 96.0
PYH1_k127_3071914_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000009362 101.0
PYH1_k127_3071914_5 biopolymer transport protein K03559 - - 0.000000000000000002799 92.0
PYH1_k127_3071914_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000004013 82.0
PYH1_k127_3088425_0 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 310.0
PYH1_k127_3088425_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 297.0
PYH1_k127_3088425_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 258.0
PYH1_k127_3088425_3 PFAM Radical SAM - - - 0.0000000000000000001377 103.0
PYH1_k127_3116974_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004539 263.0
PYH1_k127_3116974_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000007697 85.0
PYH1_k127_3116974_2 Haemolytic - - - 0.000000000002195 72.0
PYH1_k127_3116974_3 protein trimerization - - - 0.0000001411 62.0
PYH1_k127_3133677_0 ammonia-lyase activity K01745 - 4.3.1.3 8.197e-265 822.0
PYH1_k127_3133677_1 TIGRFAM Bacterial surface protein 26-residue repeat - - - 0.0000000000000000000000000000000000000000000000000004724 201.0
PYH1_k127_3133677_2 pathogenesis K02417,K02519 - - 0.000000000000000000007905 103.0
PYH1_k127_3133677_3 PFAM ABC transporter related K01990 - - 0.00000001055 57.0
PYH1_k127_3152837_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000008754 271.0
PYH1_k127_3152837_1 chemotaxis - - - 0.00000001863 59.0
PYH1_k127_3152837_2 Two component signalling adaptor domain K03408 - - 0.00002311 52.0
PYH1_k127_3202337_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1133.0
PYH1_k127_3202337_1 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001542 287.0
PYH1_k127_3202337_2 Hep Hag repeat protein - - - 0.0000000000002137 75.0
PYH1_k127_3202337_3 Cytochrome C biogenesis protein - - - 0.000000009016 66.0
PYH1_k127_3210321_0 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 476.0
PYH1_k127_3217689_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000002379 216.0
PYH1_k127_3217689_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000005339 76.0
PYH1_k127_3217689_2 - - - - 0.000003766 56.0
PYH1_k127_3225103_0 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 376.0
PYH1_k127_3225103_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 372.0
PYH1_k127_3225103_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000003362 89.0
PYH1_k127_3225103_3 Tetratricopeptide repeat - - - 0.0004015 53.0
PYH1_k127_3228068_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 449.0
PYH1_k127_3228068_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000003844 133.0
PYH1_k127_3228068_2 Outer membrane receptor K02014 - - 0.00001251 57.0
PYH1_k127_3231283_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 537.0
PYH1_k127_3231283_1 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 382.0
PYH1_k127_3231283_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000008565 177.0
PYH1_k127_3231283_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000006486 91.0
PYH1_k127_3231283_4 NmrA-like family K01784 - 5.1.3.2 0.0000002198 55.0
PYH1_k127_323837_0 lyase activity K01387,K03301 - 3.4.24.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 331.0
PYH1_k127_323837_1 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000004393 228.0
PYH1_k127_3259698_0 Carbon starvation protein K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 568.0
PYH1_k127_3259698_1 glycyl-tRNA synthetase, tetrameric type, beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000001021 168.0
PYH1_k127_3295978_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 361.0
PYH1_k127_3295978_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000003717 229.0
PYH1_k127_3295978_2 nuclear chromosome segregation - - - 0.00000000000000000000000000000000001421 153.0
PYH1_k127_3320592_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.747e-201 657.0
PYH1_k127_3320592_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 392.0
PYH1_k127_3320592_2 Outer membrane lipoprotein K05807,K08309 - - 0.0000000000000000000000000000000000000001729 158.0
PYH1_k127_3320592_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000004017 158.0
PYH1_k127_3320592_4 binding-protein-dependent transport systems inner membrane component K02025,K15771 - - 0.0000000000000000000000000000004556 127.0
PYH1_k127_3320592_5 DivIVA protein K04074,K07484 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000004135 103.0
PYH1_k127_3320592_6 Xylose isomerase-like TIM barrel - - - 0.00001482 52.0
PYH1_k127_3320592_7 Tetratricopeptide repeat - - - 0.0008696 50.0
PYH1_k127_332935_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000006833 158.0
PYH1_k127_332935_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K18105 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.5 0.0000000000000000001272 92.0
PYH1_k127_332935_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00005834 50.0
PYH1_k127_3338026_0 ABC transporter transmembrane region K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 582.0
PYH1_k127_3338026_1 ABC transporter transmembrane region K18889 - - 0.000000000000000000000000000000000000000008815 156.0
PYH1_k127_3338026_2 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000008043 121.0
PYH1_k127_3338026_3 signal peptide peptidase SppA K04773 - - 0.00000001601 64.0
PYH1_k127_3400187_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 379.0
PYH1_k127_3400187_1 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 350.0
PYH1_k127_3400187_2 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001933 273.0
PYH1_k127_3400187_3 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000003055 72.0
PYH1_k127_3414250_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.991e-249 784.0
PYH1_k127_3414250_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
PYH1_k127_3414250_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000006795 128.0
PYH1_k127_3414250_11 transmembrane transport K16052 - - 0.000004338 58.0
PYH1_k127_3414250_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 297.0
PYH1_k127_3414250_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001382 258.0
PYH1_k127_3414250_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000001178 219.0
PYH1_k127_3414250_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000003005 195.0
PYH1_k127_3414250_6 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000001278 190.0
PYH1_k127_3414250_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000001082 175.0
PYH1_k127_3414250_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001736 156.0
PYH1_k127_3414250_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000008907 148.0
PYH1_k127_3440583_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 347.0
PYH1_k127_3440583_1 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000003699 214.0
PYH1_k127_3440583_2 tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000001737 89.0
PYH1_k127_3440583_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000008183 49.0
PYH1_k127_3448337_0 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 279.0
PYH1_k127_3448337_1 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000001023 155.0
PYH1_k127_3448337_2 translation initiation factor activity K06996 - - 0.0000000000000000003264 93.0
PYH1_k127_3448337_3 - - - - 0.0000000000001282 79.0
PYH1_k127_3448337_4 ATPases associated with a variety of cellular activities K02006 - - 0.0000001812 54.0
PYH1_k127_345648_0 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000006022 247.0
PYH1_k127_345648_1 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000000000000000000000000000000003464 190.0
PYH1_k127_345648_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000001348 94.0
PYH1_k127_345648_3 - - - - 0.00000000000000513 81.0
PYH1_k127_3471279_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 411.0
PYH1_k127_3471279_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000008161 166.0
PYH1_k127_3471279_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000001838 93.0
PYH1_k127_3558584_0 lipopolysaccharide metabolic process K07502,K08309,K19804,K21572 - - 0.00000000000000000000000000000000000000005905 166.0
PYH1_k127_3558584_1 Chain length determinant protein K16554 - - 0.0000000000000000000000000001184 131.0
PYH1_k127_3558584_2 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000002755 117.0
PYH1_k127_3558584_3 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000251 77.0
PYH1_k127_3558584_5 Protein of unknown function DUF86 - - - 0.0002412 49.0
PYH1_k127_3581968_0 Belongs to the ClpA ClpB family K03696 - - 5.049e-210 665.0
PYH1_k127_3581968_1 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000006443 164.0
PYH1_k127_3581968_2 helix_turn_helix, Arsenical Resistance Operon Repressor K21885 - - 0.0004192 48.0
PYH1_k127_3633147_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 515.0
PYH1_k127_3633147_1 arginyl-tRNA aminoacylation K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 441.0
PYH1_k127_3633147_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000002633 231.0
PYH1_k127_3633147_3 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000002539 134.0
PYH1_k127_3633147_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000001344 110.0
PYH1_k127_3633147_5 TRANSCRIPTIONal - - - 0.00000000000001521 78.0
PYH1_k127_3633147_6 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000002188 75.0
PYH1_k127_3633147_7 C4-type zinc ribbon domain K07164 - - 0.00000002798 64.0
PYH1_k127_3634356_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000001306 136.0
PYH1_k127_3655561_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
PYH1_k127_3655561_1 UbiE COQ5 - - - 0.0000000000000000000000000000000000000000000003868 171.0
PYH1_k127_3655561_2 - - - - 0.00000000000003338 78.0
PYH1_k127_3658556_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000004807 189.0
PYH1_k127_3670023_0 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003242 261.0
PYH1_k127_3670023_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000007008 216.0
PYH1_k127_3670023_2 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.00000000000000000000000000000000000000000005595 183.0
PYH1_k127_3670023_3 - - - - 0.00000000000000000000000000000000000000001217 154.0
PYH1_k127_3684715_0 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 431.0
PYH1_k127_3684715_1 FlgD Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003226 261.0
PYH1_k127_3684715_2 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000191 211.0
PYH1_k127_3701980_0 LVIVD repeat - - - 0.00000000653 68.0
PYH1_k127_3712572_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 334.0
PYH1_k127_3712572_1 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 280.0
PYH1_k127_3722387_0 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 302.0
PYH1_k127_3722387_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000135 246.0
PYH1_k127_3722387_2 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000004501 230.0
PYH1_k127_3722387_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000004457 149.0
PYH1_k127_3726072_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 2.043e-208 660.0
PYH1_k127_3726072_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 475.0
PYH1_k127_372849_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 469.0
PYH1_k127_372849_1 Tryptophanyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 403.0
PYH1_k127_372849_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 364.0
PYH1_k127_372849_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007459 296.0
PYH1_k127_372849_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000522 244.0
PYH1_k127_372849_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000001565 154.0
PYH1_k127_372849_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000007369 100.0
PYH1_k127_3746327_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 340.0
PYH1_k127_3746327_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 296.0
PYH1_k127_3746327_2 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000005203 186.0
PYH1_k127_3746327_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000001414 59.0
PYH1_k127_3749412_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000002489 240.0
PYH1_k127_3749412_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001917 181.0
PYH1_k127_3749412_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000543 177.0
PYH1_k127_3749412_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000008038 164.0
PYH1_k127_3749412_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000001736 124.0
PYH1_k127_3749412_5 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001876 67.0
PYH1_k127_3750232_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000004667 183.0
PYH1_k127_3750232_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000002269 161.0
PYH1_k127_3750232_2 Ribosomal protein L17 K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000008797 117.0
PYH1_k127_3775203_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000006983 226.0
PYH1_k127_3775203_1 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000001368 210.0
PYH1_k127_3775203_2 Signal peptidase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000003149 177.0
PYH1_k127_3775203_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000391 128.0
PYH1_k127_3775203_4 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0000000000000001538 80.0
PYH1_k127_3790962_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000001268 79.0
PYH1_k127_3790962_1 TonB-dependent receptor - - - 0.00000000001546 74.0
PYH1_k127_3792152_0 leucine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000008941 233.0
PYH1_k127_3792152_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005711 231.0
PYH1_k127_3826225_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000002698 228.0
PYH1_k127_3838346_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
PYH1_k127_3838346_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 292.0
PYH1_k127_3838346_2 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000399 218.0
PYH1_k127_3838346_3 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000907 169.0
PYH1_k127_3846645_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001942 287.0
PYH1_k127_3846645_1 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000003218 114.0
PYH1_k127_3846645_2 toxin-antitoxin pair type II binding - - - 0.00000002972 57.0
PYH1_k127_3876573_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 429.0
PYH1_k127_3876573_1 polysaccharide export K01991 - - 0.0000000000000000000000000000000001166 148.0
PYH1_k127_3903471_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 396.0
PYH1_k127_3903471_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000001639 240.0
PYH1_k127_3903471_2 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000003625 201.0
PYH1_k127_3903471_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000000000007891 109.0
PYH1_k127_3903471_4 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000000000000002646 80.0
PYH1_k127_393352_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000009726 151.0
PYH1_k127_393352_1 Phenazine biosynthesis protein phzf family - - - 0.0000000000000001641 83.0
PYH1_k127_393352_2 OsmC-like protein K07397 - - 0.00000000004162 69.0
PYH1_k127_393352_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000324 57.0
PYH1_k127_3960380_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 579.0
PYH1_k127_3960380_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 425.0
PYH1_k127_3960380_2 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008633 263.0
PYH1_k127_3960380_3 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000002992 206.0
PYH1_k127_3960380_4 PFAM Tetratricopeptide - - - 0.00000000111 69.0
PYH1_k127_3960380_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000006751 61.0
PYH1_k127_3960380_6 cellulose binding K00505 - 1.14.18.1 0.00000001049 63.0
PYH1_k127_3960380_7 Phosphopantetheine attachment site - - - 0.0000001147 57.0
PYH1_k127_3971134_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 428.0
PYH1_k127_3971134_1 Fibronectin type 3 domain - - - 0.0000000003479 67.0
PYH1_k127_3978057_0 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 581.0
PYH1_k127_3978057_1 Type II secretion system protein E K02652 - - 0.000000000000000000005536 98.0
PYH1_k127_3990848_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1030.0
PYH1_k127_3990848_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000002829 185.0
PYH1_k127_3999471_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 396.0
PYH1_k127_3999471_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000015 218.0
PYH1_k127_3999471_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000002778 194.0
PYH1_k127_3999471_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000005253 162.0
PYH1_k127_3999471_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000293 92.0
PYH1_k127_3999471_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000007994 87.0
PYH1_k127_3999471_6 cellulose binding - - - 0.000404 47.0
PYH1_k127_4045251_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 4.844e-259 814.0
PYH1_k127_4045251_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 580.0
PYH1_k127_4045251_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 361.0
PYH1_k127_4045251_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000001687 204.0
PYH1_k127_4045251_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000005978 126.0
PYH1_k127_4045251_5 RQC domain - - - 0.00000000000000000000002866 112.0
PYH1_k127_4045251_6 Protein of unknown function (DUF721) - - - 0.000000000001279 74.0
PYH1_k127_4065589_0 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000001718 198.0
PYH1_k127_4065589_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000137 125.0
PYH1_k127_4080608_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000006164 244.0
PYH1_k127_4080608_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000005598 169.0
PYH1_k127_4080608_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000006588 150.0
PYH1_k127_4080608_3 peptidyl-tyrosine sulfation - - - 0.00000000000000004138 96.0
PYH1_k127_4088246_0 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
PYH1_k127_4090945_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 490.0
PYH1_k127_4090945_1 imidazolonepropionase activity K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 321.0
PYH1_k127_4090945_10 Tetratricopeptide repeat - - - 0.000425 53.0
PYH1_k127_4090945_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 287.0
PYH1_k127_4090945_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006821 242.0
PYH1_k127_4090945_4 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000003909 172.0
PYH1_k127_4090945_5 Tetratricopeptide repeat - - - 0.000000000000000000000003785 119.0
PYH1_k127_4090945_6 proteolysis K03665 - - 0.00000000000000000001655 96.0
PYH1_k127_4090945_7 - - - - 0.000000000000007073 87.0
PYH1_k127_4090945_8 Tetratricopeptide repeats - - - 0.0000000000003154 83.0
PYH1_k127_4090945_9 chaperone-mediated protein folding - - - 0.0000002375 64.0
PYH1_k127_4093717_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 417.0
PYH1_k127_4093717_1 SCO1/SenC - - - 0.00000000000000000000000000000000000000000000000000000196 202.0
PYH1_k127_4093717_2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000001021 178.0
PYH1_k127_4093717_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000000000000000000000003836 134.0
PYH1_k127_4093717_4 - - - - 0.00000000000002195 77.0
PYH1_k127_4113458_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000002727 227.0
PYH1_k127_4113458_1 outer membrane efflux protein - - - 0.000001394 57.0
PYH1_k127_4131579_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 588.0
PYH1_k127_4131579_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 420.0
PYH1_k127_4131579_2 transcriptional activator domain - - - 0.0000000000378 73.0
PYH1_k127_4136663_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 355.0
PYH1_k127_4146781_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 440.0
PYH1_k127_4146781_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000001883 208.0
PYH1_k127_4153076_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.82e-219 701.0
PYH1_k127_4153076_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000001202 165.0
PYH1_k127_4153076_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000001056 102.0
PYH1_k127_4153600_0 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 395.0
PYH1_k127_4153600_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.0000000000000000000000000000001039 139.0
PYH1_k127_4173023_0 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000005915 163.0
PYH1_k127_4173023_1 to Saccharomyces cerevisiae TOM71 (YHR117W) and TOM70 (YNL121C) K17768 GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0017038,GO:0019867,GO:0030150,GO:0030943,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0045039,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:0090151,GO:0098573,GO:0098588,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1990542 - 0.000000002593 68.0
PYH1_k127_4173457_0 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 322.0
PYH1_k127_4173457_1 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006576 260.0
PYH1_k127_4173457_2 PFAM 4Fe-4S K00176 - 1.2.7.3 0.0000000000000000000004137 98.0
PYH1_k127_4187460_0 - - - - 0.000000000000000000008206 101.0
PYH1_k127_4187460_1 Bacterial PH domain - - - 0.0000000162 64.0
PYH1_k127_4204937_0 Penicillin-binding Protein dimerisation domain K03587,K08384,K08724,K12552,K12556 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 329.0
PYH1_k127_4204937_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000456 248.0
PYH1_k127_4204937_2 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000403 104.0
PYH1_k127_4204937_3 antisigma factor binding - - - 0.0000000184 60.0
PYH1_k127_4204995_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 543.0
PYH1_k127_4204995_1 alanine dehydrogenase activity K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 308.0
PYH1_k127_4204995_2 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000008842 143.0
PYH1_k127_4204995_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000001381 57.0
PYH1_k127_4224276_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 441.0
PYH1_k127_4224276_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 416.0
PYH1_k127_4224276_2 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000001355 216.0
PYH1_k127_4224276_3 Belongs to the peptidase M48B family K03799 - - 0.000003334 60.0
PYH1_k127_4224759_0 FecR protein - - - 0.00001205 55.0
PYH1_k127_4224759_1 Methyltransferase - - - 0.00002828 54.0
PYH1_k127_4235864_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 395.0
PYH1_k127_4235864_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 296.0
PYH1_k127_4241303_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 370.0
PYH1_k127_4241303_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0000000000000000000000001307 109.0
PYH1_k127_4242405_0 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 461.0
PYH1_k127_4270843_0 Alpha-2-macroglobulin family K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 323.0
PYH1_k127_4270843_1 metallopeptidase activity K06974 - - 0.00000000000000000000000000000000000000000000002656 175.0
PYH1_k127_4272675_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 400.0
PYH1_k127_4272675_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 334.0
PYH1_k127_4272675_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000009825 215.0
PYH1_k127_4275103_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 327.0
PYH1_k127_4275103_1 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000002936 195.0
PYH1_k127_4275103_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000001148 168.0
PYH1_k127_4279108_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 454.0
PYH1_k127_4279108_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000876 204.0
PYH1_k127_4279108_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000009103 153.0
PYH1_k127_4279108_3 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00001093 54.0
PYH1_k127_4279108_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00006735 46.0
PYH1_k127_430674_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567,K04568 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 532.0
PYH1_k127_430674_1 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 325.0
PYH1_k127_430674_2 PFAM Enoyl-CoA hydratase isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000004354 251.0
PYH1_k127_430674_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
PYH1_k127_430674_4 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000006446 220.0
PYH1_k127_430674_5 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.0000000000000000000000000000000004921 136.0
PYH1_k127_430674_6 Psort location Cytoplasmic, score 8.96 K19411 - - 0.000000000000000000000000002173 117.0
PYH1_k127_4322823_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000001176 221.0
PYH1_k127_4322823_1 Leucyl aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.00000000000000000000000004429 119.0
PYH1_k127_4343701_0 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 507.0
PYH1_k127_4343701_1 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 406.0
PYH1_k127_4343701_2 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 362.0
PYH1_k127_4343701_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000104 221.0
PYH1_k127_4343701_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000005759 194.0
PYH1_k127_4343701_5 4Fe-4S double cluster binding domain - - - 0.000000000000000000000000000000000000000000000002079 181.0
PYH1_k127_4343701_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000005881 166.0
PYH1_k127_4343701_7 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000001182 122.0
PYH1_k127_4343701_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000007078 123.0
PYH1_k127_4343701_9 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000004558 89.0
PYH1_k127_4413821_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1066.0
PYH1_k127_4413821_1 Large extracellular alpha-helical protein - - - 0.0000000000000000000000000000000000000001821 172.0
PYH1_k127_4413821_2 - - - - 0.00000000000000000000000000003707 123.0
PYH1_k127_4419041_0 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000004632 194.0
PYH1_k127_4419041_1 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.00000000000001655 84.0
PYH1_k127_445029_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 345.0
PYH1_k127_445029_1 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K01802,K07533 - 5.2.1.8 0.0000000001571 72.0
PYH1_k127_445029_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000002365 64.0
PYH1_k127_4471316_0 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000213 237.0
PYH1_k127_4471316_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
PYH1_k127_4471316_2 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000006016 186.0
PYH1_k127_4471316_3 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000000000000000000000000000000000000064 175.0
PYH1_k127_4471316_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000003619 168.0
PYH1_k127_4471316_5 PFAM TPR repeat-containing protein - - - 0.00000000017 71.0
PYH1_k127_447462_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 550.0
PYH1_k127_447462_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 494.0
PYH1_k127_447462_2 PFAM Aldehyde dehydrogenase K00131 - 1.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 454.0
PYH1_k127_447462_3 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02768,K02769,K02770 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 0.000000000000000000000000000000001705 134.0
PYH1_k127_447462_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000009166 115.0
PYH1_k127_447462_5 PFAM BioY protein K03523 - - 0.000000000000000000000000001134 119.0
PYH1_k127_447462_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000008745 57.0
PYH1_k127_447462_7 PFAM UspA domain protein - - - 0.00001406 53.0
PYH1_k127_449933_0 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000001398 197.0
PYH1_k127_449933_1 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000001116 171.0
PYH1_k127_449933_2 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000001662 123.0
PYH1_k127_4504756_0 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008962 247.0
PYH1_k127_4504756_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008124 242.0
PYH1_k127_4504756_2 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000000000000000000000000000000005412 214.0
PYH1_k127_4504756_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K14696 - - 0.00000000000000000000183 97.0
PYH1_k127_4534396_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002435 291.0
PYH1_k127_4534396_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000001968 103.0
PYH1_k127_4594078_0 Domain of unknown function (DUF1846) - - - 7.077e-241 752.0
PYH1_k127_460556_0 - - - - 0.00000000000000000000000000000000219 143.0
PYH1_k127_460556_1 serine threonine protein kinase - - - 0.00000000000000000000000003145 115.0
PYH1_k127_460556_2 PKD domain - - - 0.000000000000000000000005805 113.0
PYH1_k127_460556_3 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000005592 101.0
PYH1_k127_460556_4 Peptidase family M28 - - - 0.000008349 55.0
PYH1_k127_460556_5 endopeptidase activity - - - 0.0002844 47.0
PYH1_k127_4613903_0 Tricorn protease C1 domain K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 498.0
PYH1_k127_4656823_0 Adenylate K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 404.0
PYH1_k127_4656823_1 Large extracellular alpha-helical protein - - - 0.0000000000000000000000005112 106.0
PYH1_k127_46734_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000004311 249.0
PYH1_k127_46734_1 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000000000000003085 194.0
PYH1_k127_46734_2 AsmA-like C-terminal region K07289,K09800 - - 0.0000000000000000000000000000000000000000000000009914 199.0
PYH1_k127_46734_3 von Willebrand factor (vWF) type A domain - - - 0.00000005925 64.0
PYH1_k127_46734_4 CBS domain K00974 - 2.7.7.72 0.0000003478 55.0
PYH1_k127_4673858_0 peptidase S16 K01338,K04076,K04770 - 3.4.21.53 8.797e-204 646.0
PYH1_k127_4673858_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 610.0
PYH1_k127_4673858_2 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 505.0
PYH1_k127_4673858_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 265.0
PYH1_k127_4673858_4 serine-type D-Ala-D-Ala carboxypeptidase activity K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000005816 254.0
PYH1_k127_4673858_5 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.00000000000000000000000000000000000000000000001243 181.0
PYH1_k127_4673858_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000005791 117.0
PYH1_k127_4673858_7 - - - - 0.00000004884 64.0
PYH1_k127_4673858_8 TPR repeat - - - 0.0000001681 65.0
PYH1_k127_4680886_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 6.325e-230 729.0
PYH1_k127_4680886_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 295.0
PYH1_k127_4680886_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002351 278.0
PYH1_k127_4680886_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002956 245.0
PYH1_k127_4680886_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000009531 162.0
PYH1_k127_4680886_5 aminopeptidase activity K05994 - 3.4.11.10 0.000000000000000000000000000000000001416 156.0
PYH1_k127_4689845_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 322.0
PYH1_k127_4689845_1 Domain of unknown function (DUF362) - - - 0.00000008907 55.0
PYH1_k127_4757335_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000002587 140.0
PYH1_k127_4757335_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000001153 100.0
PYH1_k127_4757335_2 Evidence 4 Homologs of previously reported genes of - - - 0.00003623 57.0
PYH1_k127_4769608_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000122 247.0
PYH1_k127_4769608_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000006188 241.0
PYH1_k127_4769608_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004256 223.0
PYH1_k127_4769608_3 Ribonuclease HII K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001939 208.0
PYH1_k127_4769608_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000232 126.0
PYH1_k127_4769608_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000005507 109.0
PYH1_k127_4769608_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000001117 90.0
PYH1_k127_4769608_7 Belongs to the UPF0102 family K07460 - - 0.0000000001514 64.0
PYH1_k127_4844395_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000124 282.0
PYH1_k127_4844395_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001555 271.0
PYH1_k127_4844395_2 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000008931 205.0
PYH1_k127_4844395_3 transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000003347 192.0
PYH1_k127_4844395_4 Histidine kinase K07683 - 2.7.13.3 0.00000000000000000000000000000001008 145.0
PYH1_k127_4844395_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00001899 57.0
PYH1_k127_4863506_0 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000002418 239.0
PYH1_k127_4863506_1 Belongs to the PdxA family K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000247 197.0
PYH1_k127_4863506_2 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000000000000007197 117.0
PYH1_k127_4878151_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 467.0
PYH1_k127_4878151_1 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000000000003956 155.0
PYH1_k127_4878151_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000001412 124.0
PYH1_k127_4878151_3 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000007192 95.0
PYH1_k127_4878151_4 amine dehydrogenase activity - - - 0.000000002374 68.0
PYH1_k127_4878151_5 Putative zinc-finger - - - 0.00002519 56.0
PYH1_k127_4880205_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 482.0
PYH1_k127_4880205_1 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000000001593 211.0
PYH1_k127_4880205_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000006207 126.0
PYH1_k127_4880205_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000168 129.0
PYH1_k127_4880205_4 - - - - 0.0003982 46.0
PYH1_k127_4900024_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.429e-213 670.0
PYH1_k127_4900024_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000001343 60.0
PYH1_k127_4923669_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1251.0
PYH1_k127_4923669_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 590.0
PYH1_k127_4923669_2 Methyltransferase, chemotaxis proteins - - - 0.000000000000000000000000000000000000000000000000000003212 207.0
PYH1_k127_4923669_3 membrane K08978 - - 0.00008495 50.0
PYH1_k127_4923669_4 Parallel beta-helix repeats - - - 0.00009551 44.0
PYH1_k127_4929714_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000003174 278.0
PYH1_k127_4929714_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000001879 247.0
PYH1_k127_4929714_2 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000003768 236.0
PYH1_k127_4929714_3 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000006494 188.0
PYH1_k127_4929714_4 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000004266 171.0
PYH1_k127_4929714_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000001229 143.0
PYH1_k127_4929714_6 Preprotein translocase subunit K03210 - - 0.00000000000000000006367 93.0
PYH1_k127_4931321_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 451.0
PYH1_k127_4931321_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
PYH1_k127_4931321_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000001696 203.0
PYH1_k127_4931321_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000005181 59.0
PYH1_k127_4973949_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 449.0
PYH1_k127_4973949_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006852 257.0
PYH1_k127_4973949_2 Dihydrodipicolinate reductase, C-terminus K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008849 237.0
PYH1_k127_4973949_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000005906 221.0
PYH1_k127_4973949_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000001115 226.0
PYH1_k127_4973949_5 - - - - 0.0000000000000001237 85.0
PYH1_k127_4973949_6 Acyltransferase K00655 - 2.3.1.51 0.0000000000000004548 83.0
PYH1_k127_4973949_7 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0006651 42.0
PYH1_k127_4982126_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 345.0
PYH1_k127_4982126_1 - - - - 0.0000000000000000000000000103 113.0
PYH1_k127_5034365_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 456.0
PYH1_k127_5034365_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 379.0
PYH1_k127_5034365_2 subunit beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001261 249.0
PYH1_k127_5034365_3 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000002922 218.0
PYH1_k127_5034365_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000003281 76.0
PYH1_k127_5044530_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.762e-213 679.0
PYH1_k127_5044530_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001138 243.0
PYH1_k127_5044530_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000005082 83.0
PYH1_k127_505803_0 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 584.0
PYH1_k127_5180614_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 332.0
PYH1_k127_5180614_1 - - - - 0.00000000000000000000000000000000000000000000000000008725 194.0
PYH1_k127_5180614_2 LppC putative lipoprotein K07121 - - 0.000000000000000000000001245 119.0
PYH1_k127_5198797_0 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000002177 216.0
PYH1_k127_5198797_1 TIGRFAM methyltransferase, MtaA CmuA family K01599 - 4.1.1.37 0.0000000000000000000000000000000000001253 154.0
PYH1_k127_5198797_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000001626 133.0
PYH1_k127_5198797_3 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000006968 123.0
PYH1_k127_5198797_4 Sigma-54 interaction domain K06714 - - 0.00000004229 63.0
PYH1_k127_5198797_5 cellulose binding - - - 0.0000002926 61.0
PYH1_k127_521798_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 439.0
PYH1_k127_521798_1 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 372.0
PYH1_k127_521798_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
PYH1_k127_521798_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001579 244.0
PYH1_k127_521798_4 PcrB family K07094 - - 0.00000000000000000000000000000000000000000000000000000000000006914 220.0
PYH1_k127_521798_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000002405 216.0
PYH1_k127_521798_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000229 216.0
PYH1_k127_521798_7 asparaginase activity K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000005573 215.0
PYH1_k127_521798_8 Protein of unknown function (DUF3795) - - - 0.00003051 52.0
PYH1_k127_5238657_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 323.0
PYH1_k127_5238657_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000001622 106.0
PYH1_k127_5238657_2 PFAM YcfA-like protein - - - 0.00000000000000002437 82.0
PYH1_k127_5244863_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008942 281.0
PYH1_k127_5244863_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000001694 154.0
PYH1_k127_5244863_2 Colicin V production protein K03558 - - 0.000000257 59.0
PYH1_k127_524774_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 540.0
PYH1_k127_524774_1 xylulokinase activity K00848 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003377 287.0
PYH1_k127_524774_2 Class II Aldolase and Adducin N-terminal domain K01629 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 0.0000000000000000000000000000000000000000000000000000000000006599 219.0
PYH1_k127_5267956_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.818e-203 642.0
PYH1_k127_5267956_1 Right handed beta helix region - - - 0.00005074 55.0
PYH1_k127_5276917_0 PFAM response regulator receiver - - - 0.0000209 51.0
PYH1_k127_530408_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000009751 230.0
PYH1_k127_530408_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000001374 139.0
PYH1_k127_530408_2 outer membrane chaperone Skp (OmpH) K06142 - - 0.0001057 51.0
PYH1_k127_5306824_0 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 291.0
PYH1_k127_5306824_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000003464 190.0
PYH1_k127_5306824_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000001124 124.0
PYH1_k127_5306824_3 cell envelope organization K05807,K06381 - - 0.0000001673 55.0
PYH1_k127_5316141_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 280.0
PYH1_k127_5316141_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001092 266.0
PYH1_k127_5316141_2 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001192 271.0
PYH1_k127_5316141_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000008128 191.0
PYH1_k127_5316141_4 polysaccharide deacetylase - - - 0.000000000000000000000005416 109.0
PYH1_k127_5326479_0 Arylsulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 558.0
PYH1_k127_5326479_1 PFAM Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000005933 224.0
PYH1_k127_5326479_2 Sulfatase K01130 - 3.1.6.1 0.000004126 54.0
PYH1_k127_5343508_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 522.0
PYH1_k127_5350335_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 293.0
PYH1_k127_5350335_1 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000502 238.0
PYH1_k127_5399849_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
PYH1_k127_5399849_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000003191 234.0
PYH1_k127_5399849_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000004279 158.0
PYH1_k127_5399849_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000001378 109.0
PYH1_k127_5444020_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 467.0
PYH1_k127_5444020_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
PYH1_k127_5444020_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 365.0
PYH1_k127_5444020_3 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000001852 219.0
PYH1_k127_5444020_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000008029 207.0
PYH1_k127_5444020_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000005688 207.0
PYH1_k127_5444020_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000003156 173.0
PYH1_k127_5445242_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 333.0
PYH1_k127_5445242_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 320.0
PYH1_k127_5445242_2 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 303.0
PYH1_k127_5445242_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 290.0
PYH1_k127_5445242_4 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000009318 218.0
PYH1_k127_5445242_5 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000002729 206.0
PYH1_k127_5445242_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000002613 171.0
PYH1_k127_5445242_7 - - - - 0.00000000000000000000001138 117.0
PYH1_k127_5445242_8 Regulatory protein - - - 0.0000000000000000000005841 100.0
PYH1_k127_5450445_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 321.0
PYH1_k127_5450445_1 LamG domain protein jellyroll fold domain protein - - - 0.000000000000000000000000000001862 136.0
PYH1_k127_5450445_2 transcriptional regulator - - - 0.000000000000000004842 93.0
PYH1_k127_5450445_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000001521 71.0
PYH1_k127_5486345_0 Tricorn protease homolog - - - 0.0 1399.0
PYH1_k127_5492630_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K12143 - - 0.00000000000000000000000000000000000000006388 159.0
PYH1_k127_5492630_1 acetyltransferase - - - 0.000164 53.0
PYH1_k127_5495239_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000001123 226.0
PYH1_k127_5495239_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000035 195.0
PYH1_k127_5586716_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
PYH1_k127_5586716_1 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000009543 174.0
PYH1_k127_5586716_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000004116 156.0
PYH1_k127_5586716_3 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.0000000000000000000000000001795 126.0
PYH1_k127_5593846_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006649 271.0
PYH1_k127_5593846_1 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000008523 223.0
PYH1_k127_5593846_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000832 164.0
PYH1_k127_5593846_3 histidine kinase HAMP region domain protein K03406 - - 0.00000000000001627 88.0
PYH1_k127_5594099_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000002599 255.0
PYH1_k127_5594099_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000002209 156.0
PYH1_k127_5598752_0 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000003919 228.0
PYH1_k127_5598752_1 - - - - 0.00001207 49.0
PYH1_k127_5645288_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 385.0
PYH1_k127_5700862_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002914 269.0
PYH1_k127_5700862_1 membrane protein (DUF2078) K08982 - - 0.0001071 44.0
PYH1_k127_5701998_0 4Fe-4S binding domain K02572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 400.0
PYH1_k127_5701998_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
PYH1_k127_5701998_3 - - - - 0.000000000005767 72.0
PYH1_k127_5723866_0 Sugar nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000001528 198.0
PYH1_k127_5723866_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000002704 126.0
PYH1_k127_5744288_0 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 403.0
PYH1_k127_5744288_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000002495 196.0
PYH1_k127_5744288_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000002547 198.0
PYH1_k127_5744288_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000008526 184.0
PYH1_k127_5753308_0 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 432.0
PYH1_k127_5753308_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 422.0
PYH1_k127_5753308_2 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000002627 239.0
PYH1_k127_5753308_3 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000000007157 178.0
PYH1_k127_5753308_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K17999 - 1.12.1.4 0.0000000000000000000000000000000000000000004783 162.0
PYH1_k127_5753308_5 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.0000000000000000000005189 98.0
PYH1_k127_5786273_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 451.0
PYH1_k127_5786273_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 302.0
PYH1_k127_5786273_2 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000001114 236.0
PYH1_k127_5801563_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000001836 142.0
PYH1_k127_5801563_1 protein containing LysM domain - - - 0.000000000000000000000006827 113.0
PYH1_k127_5801563_2 Tetratricopeptide repeat - - - 0.00000001863 67.0
PYH1_k127_5801563_3 Domain of unknown function (DUF1844) - - - 0.00001962 50.0
PYH1_k127_5872149_0 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004357 295.0
PYH1_k127_5872149_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
PYH1_k127_5876237_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001088 269.0
PYH1_k127_5876237_1 polysaccharide biosynthetic process K00655,K00721 - 2.3.1.51,2.4.1.83 0.000002641 51.0
PYH1_k127_589957_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 410.0
PYH1_k127_589957_1 photosystem II stabilization - - - 0.00002906 54.0
PYH1_k127_5906832_0 Adenylate K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 342.0
PYH1_k127_5906832_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000904 54.0
PYH1_k127_5916144_0 BadF BadG BcrA BcrD - - - 0.0 1236.0
PYH1_k127_5916144_1 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000005717 157.0
PYH1_k127_5941068_0 phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 319.0
PYH1_k127_5941068_1 penicillin-binding protein - - - 0.0000000000000531 82.0
PYH1_k127_5941068_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000001699 62.0
PYH1_k127_594484_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 613.0
PYH1_k127_594484_1 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 512.0
PYH1_k127_594484_2 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 501.0
PYH1_k127_594484_3 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000003708 201.0
PYH1_k127_594484_4 Type IV pilin PilA - - - 0.00000007933 60.0
PYH1_k127_594484_6 Prokaryotic N-terminal methylation motif K02672 - - 0.00004995 55.0
PYH1_k127_594484_7 RHS Repeat - - - 0.00005141 54.0
PYH1_k127_5966261_0 COG2909 ATP-dependent transcriptional regulator K03556 - - 0.0000000000000000000000000000000000000000000000000000000001652 224.0
PYH1_k127_5966261_1 - - - - 0.0000000000000000000000000000000000000002763 157.0
PYH1_k127_5972340_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.621e-210 666.0
PYH1_k127_5972340_1 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02246,K08084 - - 0.00001259 51.0
PYH1_k127_5985597_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002566 277.0
PYH1_k127_5985597_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000009955 223.0
PYH1_k127_5985597_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000008177 177.0
PYH1_k127_5994784_0 OPT oligopeptide transporter protein - - - 3.834e-222 707.0
PYH1_k127_5994784_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 424.0
PYH1_k127_5994784_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005658 269.0
PYH1_k127_5994784_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000001166 236.0
PYH1_k127_5994784_4 pectinesterase activity K10117 - - 0.00000000006073 75.0
PYH1_k127_5994784_5 Evidence 5 No homology to any previously reported sequences K07004,K09955 - - 0.000000000319 72.0
PYH1_k127_5994784_6 DNA-binding transcription factor activity K21903,K22043 - - 0.000009884 51.0
PYH1_k127_6001882_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001425 242.0
PYH1_k127_6001882_1 PKD domain - - - 0.00000000000000000000007562 106.0
PYH1_k127_6001882_2 PFAM FG-GAP repeat protein - - - 0.0000000000001751 81.0
PYH1_k127_6001882_3 bacterial-type flagellum-dependent cell motility K16147 - 2.4.99.16 0.000000000002368 79.0
PYH1_k127_6001882_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00003948 52.0
PYH1_k127_6013276_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 409.0
PYH1_k127_6013276_1 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000001176 188.0
PYH1_k127_6013276_2 N-terminal domain of unknown function (DUF4140) - - - 0.00000002558 61.0
PYH1_k127_6013276_3 Aminotransferase class-V K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.00000005365 56.0
PYH1_k127_602064_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 443.0
PYH1_k127_602064_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 306.0
PYH1_k127_602064_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000001056 154.0
PYH1_k127_6035104_0 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 536.0
PYH1_k127_6035104_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 476.0
PYH1_k127_6035104_2 penicillin binding K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 378.0
PYH1_k127_6035104_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 292.0
PYH1_k127_6035104_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000009766 218.0
PYH1_k127_6035104_5 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000003698 200.0
PYH1_k127_6035104_6 PFAM Phosphoribosyltransferase K02242 - - 0.000000000000000000000000000000000000000000001555 175.0
PYH1_k127_6035104_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000001188 154.0
PYH1_k127_6085991_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 369.0
PYH1_k127_6085991_1 PFAM Uncharacterised protein family (UPF0164) - - - 0.00000000000000000000000000000000000000000000000000000000005206 218.0
PYH1_k127_6085991_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000001542 210.0
PYH1_k127_6085991_3 Belongs to the peptidase S8 family K07093 - - 0.000000001123 61.0
PYH1_k127_6111765_0 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.0000000000000000000002538 104.0
PYH1_k127_6111765_1 PTS system mannose/fructose/sorbose family IID component K02796 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 - 0.0000000000000000000007349 105.0
PYH1_k127_6111765_2 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000002669 90.0
PYH1_k127_6111765_3 PTS system sorbose-specific iic component - - - 0.00000004517 63.0
PYH1_k127_6131246_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000001299 248.0
PYH1_k127_6131246_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000005696 216.0
PYH1_k127_6131246_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000008121 207.0
PYH1_k127_6131246_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000001705 126.0
PYH1_k127_6131246_4 - - - - 0.0000000000000005712 83.0
PYH1_k127_6152637_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004261 293.0
PYH1_k127_6152637_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000002805 68.0
PYH1_k127_6152637_2 HEAT repeats K01387 - 3.4.24.3 0.000000003494 63.0
PYH1_k127_6172938_0 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000002619 149.0
PYH1_k127_6172938_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000006961 127.0
PYH1_k127_6172938_2 Helix-hairpin-helix motif - - - 0.00000000000000000000001835 115.0
PYH1_k127_6183064_0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001288 287.0
PYH1_k127_6183064_1 Methyltransferase type 11 K01921 - 6.3.2.4 0.000000000000000000000000000000004959 132.0
PYH1_k127_6183064_2 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 0.0000168 52.0
PYH1_k127_6183713_0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002219 204.0
PYH1_k127_6183713_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000002937 201.0
PYH1_k127_6183713_2 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000811 78.0
PYH1_k127_6183713_3 GIY-YIG catalytic domain protein K07461 - - 0.000000003351 60.0
PYH1_k127_618933_0 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002718 279.0
PYH1_k127_618933_1 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000004301 126.0
PYH1_k127_618933_2 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000002413 121.0
PYH1_k127_618933_3 amine dehydrogenase activity K14274 - - 0.00000000000000004881 94.0
PYH1_k127_6201349_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 544.0
PYH1_k127_6201349_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000001916 264.0
PYH1_k127_6224604_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 531.0
PYH1_k127_6224604_1 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000007144 241.0
PYH1_k127_6238414_0 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 584.0
PYH1_k127_6238414_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000001338 185.0
PYH1_k127_6242040_0 - - - - 0.0000000000000000000000000000003953 134.0
PYH1_k127_6259047_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003129 252.0
PYH1_k127_6259047_1 Required for chromosome condensation and partitioning K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000001839 228.0
PYH1_k127_6259047_2 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000282 76.0
PYH1_k127_6274422_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000001094 217.0
PYH1_k127_6274422_1 Renal dipeptidase family protein K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000945 179.0
PYH1_k127_6274422_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000003279 66.0
PYH1_k127_6274422_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0001028 55.0
PYH1_k127_6289547_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 419.0
PYH1_k127_6289547_1 Belongs to the ompA family - - - 0.0000000000000000000000000000003318 130.0
PYH1_k127_6312523_0 Belongs to the ompA family - - - 0.000000000000000000001645 108.0
PYH1_k127_6312523_1 long-chain fatty acid transport protein - - - 0.0000002018 63.0
PYH1_k127_631324_0 RNA ligase activity K14415,K18148 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0030312,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 405.0
PYH1_k127_631324_1 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002967 254.0
PYH1_k127_6385178_0 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008465 263.0
PYH1_k127_6385178_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000002922 208.0
PYH1_k127_6385178_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000002173 61.0
PYH1_k127_6394565_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 493.0
PYH1_k127_6394565_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000002547 195.0
PYH1_k127_6394565_2 PFAM glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000008735 182.0
PYH1_k127_6394565_3 metallopeptidase activity K06974 - - 0.0000000000000000000000000004131 121.0
PYH1_k127_6394565_4 cheY-homologous receiver domain K07658 - - 0.000000000000000000002583 98.0
PYH1_k127_6418892_0 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 452.0
PYH1_k127_6418892_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008096 316.0
PYH1_k127_6427019_0 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000001215 169.0
PYH1_k127_6432787_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 352.0
PYH1_k127_6432787_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000001923 191.0
PYH1_k127_6432787_2 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.00000000000000000000000005912 117.0
PYH1_k127_6432787_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000002432 91.0
PYH1_k127_6432787_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000007915 85.0
PYH1_k127_6432787_5 - - - - 0.00000000000000009465 81.0
PYH1_k127_6432787_6 ATP synthase F(0) sector subunit b K02109 - - 0.0000000000000001011 89.0
PYH1_k127_6461504_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 552.0
PYH1_k127_6461504_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 505.0
PYH1_k127_6461504_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002406 232.0
PYH1_k127_6461504_3 Domain of unknown function (4846) - - - 0.000000000000000000000000000000000000000000000000000003701 194.0
PYH1_k127_6461504_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000002086 89.0
PYH1_k127_6461504_5 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.00002534 52.0
PYH1_k127_648522_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000001756 240.0
PYH1_k127_6500218_0 Threonine synthase N terminus K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 532.0
PYH1_k127_6500218_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 491.0
PYH1_k127_6500218_2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 481.0
PYH1_k127_6500218_3 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000327 111.0
PYH1_k127_6508228_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 437.0
PYH1_k127_6508228_1 COG0457 FOG TPR repeat - - - 0.000000000000004065 90.0
PYH1_k127_6508228_2 Tetratricopeptide repeat - - - 0.0000004294 63.0
PYH1_k127_65226_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 475.0
PYH1_k127_65226_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000001223 133.0
PYH1_k127_65226_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000005259 111.0
PYH1_k127_65226_3 transmembrane transcriptional regulator (anti-sigma factor) - - - 0.0001591 47.0
PYH1_k127_6539783_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 461.0
PYH1_k127_6539783_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K16079 - - 0.00000000000000000000000000001095 137.0
PYH1_k127_6556177_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 468.0
PYH1_k127_6556177_1 Rubredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007588 265.0
PYH1_k127_6556177_2 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002534 220.0
PYH1_k127_6564246_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00973,K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000001739 226.0
PYH1_k127_6564246_1 lipopolysaccharide metabolic process K08309,K19804 - - 0.0000000000001529 81.0
PYH1_k127_6564246_2 transferase activity, transferring glycosyl groups - - - 0.000000000004418 68.0
PYH1_k127_6568135_0 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 363.0
PYH1_k127_6568135_1 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000008851 162.0
PYH1_k127_6568135_2 - - - - 0.00000000002303 70.0
PYH1_k127_6576789_0 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000135 216.0
PYH1_k127_6576789_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000003651 123.0
PYH1_k127_6576789_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000001391 114.0
PYH1_k127_6576789_3 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000003665 85.0
PYH1_k127_6588728_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 319.0
PYH1_k127_6588728_1 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000000000000354 254.0
PYH1_k127_6588728_2 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000000000000000000000000002575 205.0
PYH1_k127_6588728_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000001028 58.0
PYH1_k127_6594743_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000002561 214.0
PYH1_k127_6594743_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000005488 84.0
PYH1_k127_6594743_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000001395 80.0
PYH1_k127_6635872_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 502.0
PYH1_k127_6635872_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 299.0
PYH1_k127_6635872_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.00000000000000000000000000000000000000000000000000000000001403 210.0
PYH1_k127_6635872_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000001385 224.0
PYH1_k127_6635872_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000002715 132.0
PYH1_k127_6635872_5 Histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000003222 86.0
PYH1_k127_6637214_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000006275 176.0
PYH1_k127_6637214_1 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000004154 118.0
PYH1_k127_6637214_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000004315 101.0
PYH1_k127_6637214_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000001649 90.0
PYH1_k127_6637214_4 S-layer homology domain - - - 0.0003295 51.0
PYH1_k127_6676124_0 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 282.0
PYH1_k127_6676124_1 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001382 221.0
PYH1_k127_6676124_2 ABC-2 type transporter K01992 - - 0.000000000000000000008327 102.0
PYH1_k127_6676124_3 ABC-2 type transporter K01992 - - 0.00000000000002868 83.0
PYH1_k127_6688400_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 439.0
PYH1_k127_6688400_1 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000002335 186.0
PYH1_k127_6688400_2 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K04763 - - 0.0000000000000000000000000007224 119.0
PYH1_k127_6741164_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 447.0
PYH1_k127_6741164_1 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 275.0
PYH1_k127_6741164_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000007689 154.0
PYH1_k127_6741164_3 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000001944 165.0
PYH1_k127_6750398_0 Domain of unknown function (DUF4438) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 429.0
PYH1_k127_6750398_1 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000001222 222.0
PYH1_k127_6750398_2 FlgD Ig-like domain K15924 - 3.2.1.136 0.0000000000002703 78.0
PYH1_k127_6750398_3 prepilin-type N-terminal cleavage methylation K02456 - - 0.0000392 53.0
PYH1_k127_6801648_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 366.0
PYH1_k127_6801648_1 lyase activity K01387,K03301 - 3.4.24.3 0.00000000000000000000000000000000000000001062 160.0
PYH1_k127_6824334_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 426.0
PYH1_k127_6824334_1 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000007723 176.0
PYH1_k127_6824334_2 Trypsin - - - 0.00001032 50.0
PYH1_k127_683029_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 402.0
PYH1_k127_683029_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 318.0
PYH1_k127_683029_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 306.0
PYH1_k127_683029_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000145 69.0
PYH1_k127_6841971_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 559.0
PYH1_k127_6841971_1 Transcriptional regulator K13652 - - 0.000000000000000000000000001321 124.0
PYH1_k127_6841971_2 4 iron, 4 sulfur cluster binding - - - 0.00000005186 58.0
PYH1_k127_6887240_0 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 435.0
PYH1_k127_6887240_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000001092 199.0
PYH1_k127_6887240_2 Involved in formation and maintenance of cell shape K03570 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000002714 83.0
PYH1_k127_6887240_3 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000551 49.0
PYH1_k127_6912534_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 335.0
PYH1_k127_6912534_1 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000171 266.0
PYH1_k127_6912534_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000001139 189.0
PYH1_k127_6912534_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000009467 180.0
PYH1_k127_6912534_4 Conserved hypothetical protein 95 - - - 0.000000000000000001521 89.0
PYH1_k127_6912534_5 Evidence 4 Homologs of previously reported genes of - - - 0.0001377 52.0
PYH1_k127_6977143_0 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000001218 238.0
PYH1_k127_6977143_1 tRNA pseudouridine synthase D (TruD) K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000001537 185.0
PYH1_k127_6977143_2 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000006238 147.0
PYH1_k127_6977143_3 methyltransferase - - - 0.0000000000000004193 86.0
PYH1_k127_6977143_4 Helix-hairpin-helix motif K02237 - - 0.000000000003026 70.0
PYH1_k127_69943_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 317.0
PYH1_k127_69943_1 YoaP-like - - - 0.00000007837 63.0
PYH1_k127_69943_2 Regulatory protein ArsR - - - 0.00007765 49.0
PYH1_k127_7014773_0 smart pdz dhr glgf K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 403.0
PYH1_k127_7014773_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 387.0
PYH1_k127_7014773_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000001619 182.0
PYH1_k127_7014773_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000771 132.0
PYH1_k127_7014773_4 cellulose binding K00505 - 1.14.18.1 0.00000000000000000000107 97.0
PYH1_k127_7028160_0 Peptidase family M3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 488.0
PYH1_k127_7028160_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 301.0
PYH1_k127_7028160_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
PYH1_k127_7028160_3 UbiE COQ5 - - - 0.0000000000000000000000000000000000000000001215 162.0
PYH1_k127_7028639_0 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 439.0
PYH1_k127_7028639_1 peptidase M42 family protein K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 369.0
PYH1_k127_7028639_2 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002744 286.0
PYH1_k127_7028639_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000004451 242.0
PYH1_k127_7028639_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000002361 179.0
PYH1_k127_7028639_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000003726 123.0
PYH1_k127_7038123_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
PYH1_k127_7038123_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 388.0
PYH1_k127_7038123_2 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000007711 178.0
PYH1_k127_7038123_3 ligase activity, forming carbon-carbon bonds K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.00000000000000000000000000000000002143 140.0
PYH1_k127_7038123_4 Tetratricopeptide repeat - - - 0.00000000000002216 85.0
PYH1_k127_7045901_0 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 285.0
PYH1_k127_7045901_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000003178 167.0
PYH1_k127_7045901_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000001123 155.0
PYH1_k127_7045901_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000001737 143.0
PYH1_k127_7045901_4 Sporulation related domain - - - 0.00002216 53.0
PYH1_k127_7073745_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 275.0
PYH1_k127_7073745_1 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000002627 222.0
PYH1_k127_7073745_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000001849 109.0
PYH1_k127_7075288_0 Belongs to the ClpA ClpB family K03696 - - 7.102e-202 642.0
PYH1_k127_7075288_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000001998 171.0
PYH1_k127_7080694_0 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 411.0
PYH1_k127_7080694_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 393.0
PYH1_k127_7080694_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000009263 171.0
PYH1_k127_7080694_3 Endonuclease I - - - 0.0000000005399 72.0
PYH1_k127_7124098_0 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000001273 169.0
PYH1_k127_7124098_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000668 183.0
PYH1_k127_7124098_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000338 167.0
PYH1_k127_7128474_0 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 287.0
PYH1_k127_7128474_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000008162 197.0
PYH1_k127_7168757_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 462.0
PYH1_k127_7168757_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000144 167.0
PYH1_k127_7168757_2 UbiA prenyltransferase family K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000002991 86.0
PYH1_k127_7199033_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 608.0
PYH1_k127_7199033_1 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000001564 202.0
PYH1_k127_7199033_2 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000000000002752 151.0
PYH1_k127_7199033_3 - - - - 0.0000000002151 73.0
PYH1_k127_7240889_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 323.0
PYH1_k127_7240889_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 297.0
PYH1_k127_7240889_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000006084 161.0
PYH1_k127_7310952_0 Domain of Unknown Function (DUF1080) - - - 0.000005476 57.0
PYH1_k127_7310952_1 Protein of unknown function (DUF1565) - - - 0.0004725 51.0
PYH1_k127_7311055_0 PFAM Radical SAM superfamily K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 317.0
PYH1_k127_7311055_1 thioesterase - - - 0.000000000000000000000000000000000000000000000000000000269 198.0
PYH1_k127_7311055_2 radical SAM domain protein K09711 - - 0.00000000000000000000004247 108.0
PYH1_k127_7333097_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 384.0
PYH1_k127_7333097_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 297.0
PYH1_k127_7333097_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001646 288.0
PYH1_k127_7369055_0 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009243 250.0
PYH1_k127_7369055_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000001436 217.0
PYH1_k127_7379767_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 398.0
PYH1_k127_7379767_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 297.0
PYH1_k127_7379767_2 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002995 268.0
PYH1_k127_7379767_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000003154 106.0
PYH1_k127_7428065_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 351.0
PYH1_k127_7428065_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000001885 166.0
PYH1_k127_7428065_2 - - - - 0.0000000000000000000000000000137 129.0
PYH1_k127_7466106_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.429e-279 873.0
PYH1_k127_7466106_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 316.0
PYH1_k127_7466106_2 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001277 298.0
PYH1_k127_7466106_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004814 259.0
PYH1_k127_7466106_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000156 169.0
PYH1_k127_7469458_0 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 509.0
PYH1_k127_7469458_1 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000005842 193.0
PYH1_k127_7469458_2 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00003797 55.0
PYH1_k127_7480563_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000004412 109.0
PYH1_k127_7480563_1 Xylose isomerase-like TIM barrel - - - 0.000000000000001401 84.0
PYH1_k127_7480563_2 PFAM Capsule synthesis protein, CapA K07282 - - 0.000000008569 66.0
PYH1_k127_748113_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000001409 215.0
PYH1_k127_748113_1 Aerotolerance regulator N-terminal - - - 0.0000000000000000001754 103.0
PYH1_k127_7508382_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 310.0
PYH1_k127_7508382_1 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007835 266.0
PYH1_k127_7536238_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000825 194.0
PYH1_k127_7536238_1 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000004237 121.0
PYH1_k127_7559596_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 391.0
PYH1_k127_7559596_1 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 335.0
PYH1_k127_7559596_2 ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000005557 195.0
PYH1_k127_7559596_3 extracellular matrix structural constituent - - - 0.000000000262 71.0
PYH1_k127_7559596_4 translation initiation factor activity K06996 - - 0.0003912 43.0
PYH1_k127_7577658_0 - - - - 0.0000000000000000000000000000000000000006177 154.0
PYH1_k127_7577658_1 Conserved repeat domain - - - 0.00000000000000000000000000000000000001253 154.0
PYH1_k127_7577658_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000001495 145.0
PYH1_k127_758432_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000001312 115.0
PYH1_k127_758432_1 Xylose isomerase-like TIM barrel - - - 0.00000002474 62.0
PYH1_k127_7608254_1 Nitroreductase family - - - 0.00000000000000000000000001377 111.0
PYH1_k127_7622088_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002047 278.0
PYH1_k127_7622088_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000001385 231.0
PYH1_k127_7622088_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0008138 45.0
PYH1_k127_7641233_0 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 349.0
PYH1_k127_7641233_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000214 104.0
PYH1_k127_7641233_2 - - - - 0.0000001494 56.0
PYH1_k127_7641233_3 Tetratricopeptide repeat - - - 0.000213 46.0
PYH1_k127_764424_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.361e-288 911.0
PYH1_k127_764424_1 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000002905 184.0
PYH1_k127_764424_2 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000002157 161.0
PYH1_k127_764424_3 hydrogenase maturation protease K03605 - - 0.0000000000001341 77.0
PYH1_k127_7653045_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 592.0
PYH1_k127_7653045_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000001815 179.0
PYH1_k127_7653045_2 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000008314 143.0
PYH1_k127_7663245_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 362.0
PYH1_k127_7663245_1 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.0000000000323 74.0
PYH1_k127_7663852_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000001257 186.0
PYH1_k127_7663852_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000005634 186.0
PYH1_k127_7675393_0 long-chain fatty acid transport protein - - - 0.000000000000000002732 96.0
PYH1_k127_7675393_1 extracellular matrix structural constituent - - - 0.00000000000003466 85.0
PYH1_k127_7675393_2 Kelch motif - - - 0.000000000001888 79.0
PYH1_k127_7687800_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 420.0
PYH1_k127_7687800_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000004084 160.0
PYH1_k127_7687800_2 mitochondrial gene expression K02935 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005759 134.0
PYH1_k127_7687800_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000006 108.0
PYH1_k127_7704235_0 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000000000006877 228.0
PYH1_k127_7704235_1 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000003998 181.0
PYH1_k127_7704235_2 PFAM CYTH domain K01768 - 4.6.1.1 0.00000000000000005141 86.0
PYH1_k127_7714166_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.822e-217 690.0
PYH1_k127_7714166_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000645 223.0
PYH1_k127_7714166_2 methyltransferase - - - 0.00000000000000000000000003103 121.0
PYH1_k127_7747715_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001299 286.0
PYH1_k127_7749641_0 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 382.0
PYH1_k127_7749641_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000001085 243.0
PYH1_k127_7749641_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K22043 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000255 47.0
PYH1_k127_7750205_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1533.0
PYH1_k127_7750205_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 4.153e-292 915.0
PYH1_k127_7750205_2 Endonuclease containing a URI domain K07461 - - 0.00000001201 57.0
PYH1_k127_778708_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000001667 215.0
PYH1_k127_778708_1 Tetratricopeptide repeat - - - 0.0000000005978 71.0
PYH1_k127_778708_2 Protein of unknown function (DUF1501) - - - 0.0008566 51.0
PYH1_k127_7787129_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000002448 89.0
PYH1_k127_7787129_1 Putative zinc-finger - - - 0.0005638 48.0
PYH1_k127_7808392_0 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 499.0
PYH1_k127_7808392_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001786 279.0
PYH1_k127_7808392_10 - - - - 0.0001148 53.0
PYH1_k127_7808392_11 phosphate-selective porin O and P - - - 0.0004836 51.0
PYH1_k127_7808392_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002971 269.0
PYH1_k127_7808392_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001098 251.0
PYH1_k127_7808392_4 Oxidoreductase K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000003485 260.0
PYH1_k127_7808392_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
PYH1_k127_7808392_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000004109 200.0
PYH1_k127_7808392_7 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000002142 209.0
PYH1_k127_7808392_8 Transcriptional regulator - - - 0.00000000000000000000000000002989 121.0
PYH1_k127_7846550_0 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
PYH1_k127_7846550_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000005118 167.0
PYH1_k127_7846550_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000008861 101.0
PYH1_k127_7863155_0 lyase activity K01387,K03301 - 3.4.24.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 445.0
PYH1_k127_788279_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 342.0
PYH1_k127_788279_1 Transcription termination factor nusG - - - 0.000000000000000000000000000003459 125.0
PYH1_k127_788279_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000002958 89.0
PYH1_k127_7890201_0 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 334.0
PYH1_k127_7890201_1 surface antigen (D15) K07277 - - 0.00000000000000000000000000000000000000000001427 184.0
PYH1_k127_7890201_2 Galactose oxidase, central domain - - - 0.000000000000000000000000000000001402 145.0
PYH1_k127_7890201_3 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000000006791 113.0
PYH1_k127_7968153_0 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000009444 131.0
PYH1_k127_7968153_1 PKD domain - - - 0.0000007937 54.0
PYH1_k127_7971805_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 553.0
PYH1_k127_7971805_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001039 144.0
PYH1_k127_7976151_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003113 288.0
PYH1_k127_7976151_1 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000001465 142.0
PYH1_k127_8015162_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.00000000000000000001579 95.0
PYH1_k127_8023979_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000005604 268.0
PYH1_k127_8023979_1 Domain of unknown function (DUF4919) - - - 0.00005303 47.0
PYH1_k127_8035473_0 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.0000000000000000000000000000000000000843 151.0
PYH1_k127_8035473_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000007461 95.0
PYH1_k127_8035473_2 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.000001504 53.0
PYH1_k127_8058179_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
PYH1_k127_8058179_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000003379 177.0
PYH1_k127_8074788_0 Tetratricopeptide repeat protein - - - 0.0000000000000000000000000000000000000000005941 181.0
PYH1_k127_8074788_1 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000000000000007687 106.0
PYH1_k127_8074788_2 TonB-dependent receptor - - - 0.000009665 58.0
PYH1_k127_8091678_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000003566 213.0
PYH1_k127_8091678_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000002961 166.0
PYH1_k127_8091678_2 Peptidase M56 - - - 0.0000000000000000000000000004668 126.0
PYH1_k127_8091678_3 Peptidase M56 - - - 0.000000000000000000000001167 118.0
PYH1_k127_8102752_0 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 306.0
PYH1_k127_8102752_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000002245 149.0
PYH1_k127_8102752_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587 - 1.6.5.3 0.000000000000000000000000000000000001753 139.0
PYH1_k127_8111570_0 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 388.0
PYH1_k127_8111570_1 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
PYH1_k127_8111570_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000009239 230.0
PYH1_k127_8111570_3 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000001052 141.0
PYH1_k127_8111570_4 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000004597 105.0
PYH1_k127_8144533_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 9.671e-302 946.0
PYH1_k127_8144533_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000004725 181.0
PYH1_k127_8144533_2 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000007523 99.0
PYH1_k127_8175637_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 394.0
PYH1_k127_8175637_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 290.0
PYH1_k127_8175637_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000002075 239.0
PYH1_k127_8175637_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
PYH1_k127_8175637_4 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000008588 111.0
PYH1_k127_8175637_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000006684 64.0
PYH1_k127_8175637_6 long-chain fatty acid transporting porin activity - - - 0.000006003 57.0
PYH1_k127_8200025_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 334.0
PYH1_k127_8200025_1 PFAM CheW domain protein K03408 - - 0.000000005175 60.0
PYH1_k127_8200025_2 PFAM zinc iron permease K16267 - - 0.000002343 51.0
PYH1_k127_8209307_0 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000007629 244.0
PYH1_k127_8209307_1 PFAM Peptidase C1A, papain - - - 0.00000000000000000000000000000000000000000000000000000103 213.0
PYH1_k127_8228064_0 VTC domain - - - 0.0000000000000000000000000000000000000000000000005043 187.0
PYH1_k127_8228064_1 pathogenesis - - - 0.000000000000000000000000000000000000000295 151.0
PYH1_k127_8228064_2 NHL repeat containing protein - - - 0.000000000000000000000000007674 117.0
PYH1_k127_8271019_0 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 286.0
PYH1_k127_8271019_1 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002045 293.0
PYH1_k127_8271019_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000001932 166.0
PYH1_k127_8271019_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000002419 142.0
PYH1_k127_8271019_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000001818 125.0
PYH1_k127_8271019_5 Domain of unknown function (DUF4412) - - - 0.0000203 55.0
PYH1_k127_8343777_0 Multicopper oxidase K08100 - 1.3.3.5 1.457e-254 804.0
PYH1_k127_8358059_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 1.804e-224 707.0
PYH1_k127_8358059_1 PFAM Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 321.0
PYH1_k127_8358059_3 Galactose oxidase, central domain - - - 0.0000000000000000000000005936 122.0
PYH1_k127_840444_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
PYH1_k127_840444_1 aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 410.0
PYH1_k127_840444_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 419.0
PYH1_k127_840444_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000005723 215.0
PYH1_k127_840444_4 - - - - 0.0000000000000000000000000000004101 133.0
PYH1_k127_840444_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000003581 92.0
PYH1_k127_840444_6 OsmC-like protein K07397 - - 0.0000000000000004969 83.0
PYH1_k127_840444_7 PFAM 2-hydroxyglutaryl-CoA dehydratase - - - 0.00000000000001605 83.0
PYH1_k127_840701_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 341.0
PYH1_k127_840701_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000295 214.0
PYH1_k127_840701_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000001865 194.0
PYH1_k127_840701_3 - - - - 0.000000000000000000000000000000000000000000000001841 181.0
PYH1_k127_840701_4 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000871 159.0
PYH1_k127_841638_0 PFAM Cupin domain - - - 0.000000000000000000000000000004233 123.0
PYH1_k127_841638_1 TonB dependent receptor K16089 - - 0.0002864 53.0
PYH1_k127_86490_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000002851 245.0
PYH1_k127_86490_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000007933 209.0
PYH1_k127_86490_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000006228 162.0
PYH1_k127_86490_3 Roadblock/LC7 domain - - - 0.000000000005956 71.0
PYH1_k127_872731_0 Acyl-CoA dehydrogenase, N-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
PYH1_k127_872731_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000007948 193.0
PYH1_k127_872731_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000007011 136.0
PYH1_k127_880409_0 endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005628 284.0
PYH1_k127_880409_1 Belongs to the UPF0761 family K07058 - - 0.000000000000000000676 96.0
PYH1_k127_884698_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
PYH1_k127_884698_1 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 260.0
PYH1_k127_884698_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate- level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01900 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042709,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0046483,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1902494 6.2.1.4,6.2.1.5 0.0005673 46.0
PYH1_k127_888486_0 Thrombospondin type 3 repeat - - - 0.000000000000000007414 96.0
PYH1_k127_888486_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000003972 62.0
PYH1_k127_888486_2 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.000001426 51.0
PYH1_k127_908219_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 8.826e-248 775.0
PYH1_k127_908219_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000001123 134.0
PYH1_k127_908219_2 Glycosyl transferase, family 2 - - - 0.000000000000002262 88.0
PYH1_k127_908219_3 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000000000001063 84.0
PYH1_k127_935579_0 - - - - 0.00000000000000000000000000000000000000000000000000001221 190.0
PYH1_k127_935579_1 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000867 185.0
PYH1_k127_935579_3 PFAM GAF domain K08968 - 1.8.4.14 0.000000000003364 66.0
PYH1_k127_944921_0 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 410.0
PYH1_k127_944921_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 334.0
PYH1_k127_944921_2 Conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 302.0
PYH1_k127_944921_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000007705 229.0
PYH1_k127_944921_4 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000002295 170.0
PYH1_k127_947526_0 exonuclease K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 435.0
PYH1_k127_947526_1 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 313.0
PYH1_k127_947526_2 Spore coat protein CotH K06330 - - 0.00000000000000000000000000000000000000000000000000000000000000001606 237.0
PYH1_k127_947526_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000005944 193.0
PYH1_k127_947526_4 - - - - 0.000000000000000000000000000000000000000000005047 173.0
PYH1_k127_947526_5 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000004896 168.0
PYH1_k127_947526_6 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000001037 119.0
PYH1_k127_947526_7 guanyl-nucleotide exchange factor activity - - - 0.0000000007614 65.0
PYH1_k127_966892_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 468.0
PYH1_k127_966892_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 336.0
PYH1_k127_966892_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000009145 173.0
PYH1_k127_966892_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000003491 108.0
PYH1_k127_966892_4 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000007135 101.0