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Overview

ID MAG03168
Name PYH1_bin.67
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family UBA5066
Genus DAOMFB01
Species
Assembly information
Completeness (%) 78.15
Contamination (%) 1.33
GC content (%) 69.0
N50 (bp) 10,790
Genome size (bp) 2,889,078

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2477

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1001816_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 491.0
PYH1_k127_1001816_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 323.0
PYH1_k127_1001816_2 microcin C7 resistance K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002642 283.0
PYH1_k127_1001816_3 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000003026 258.0
PYH1_k127_1001816_4 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000001829 229.0
PYH1_k127_1001816_5 nuclear chromosome segregation - - - 0.000000000000003334 86.0
PYH1_k127_1001816_6 O-methyltransferase K00588 - 2.1.1.104 0.000000000421 66.0
PYH1_k127_1001816_7 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00027 48.0
PYH1_k127_1053549_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.033e-245 802.0
PYH1_k127_1053549_1 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001812 262.0
PYH1_k127_1053549_10 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000002602 87.0
PYH1_k127_1053549_11 outer membrane autotransporter barrel domain protein - - - 0.00000003683 66.0
PYH1_k127_1053549_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002734 249.0
PYH1_k127_1053549_3 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000003991 241.0
PYH1_k127_1053549_4 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000009071 192.0
PYH1_k127_1053549_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000001655 162.0
PYH1_k127_1053549_6 DinB family - - - 0.00000000000000000000000000000000000001254 154.0
PYH1_k127_1053549_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000009886 138.0
PYH1_k127_1053549_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000003981 133.0
PYH1_k127_1053549_9 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000004275 110.0
PYH1_k127_1104342_0 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 443.0
PYH1_k127_1104342_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 362.0
PYH1_k127_1104342_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 334.0
PYH1_k127_1104342_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000004247 108.0
PYH1_k127_1112535_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 415.0
PYH1_k127_1112535_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000827 198.0
PYH1_k127_1112535_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000001079 195.0
PYH1_k127_1112535_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000005976 105.0
PYH1_k127_1112535_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000145 69.0
PYH1_k127_1112535_5 - - - - 0.00000000001712 65.0
PYH1_k127_1112535_6 lipolytic protein G-D-S-L family - - - 0.00000000009835 74.0
PYH1_k127_1112535_7 - - - - 0.0007774 52.0
PYH1_k127_112189_0 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
PYH1_k127_112189_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000002113 209.0
PYH1_k127_112189_2 - - - - 0.00000000000000000000000000000000000002394 151.0
PYH1_k127_112189_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000001708 157.0
PYH1_k127_112189_4 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000001181 120.0
PYH1_k127_112189_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000005321 119.0
PYH1_k127_112189_6 nuclease activity K06218 - - 0.00000000000000002221 87.0
PYH1_k127_1134699_0 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 293.0
PYH1_k127_1134699_1 PFAM Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 259.0
PYH1_k127_1140556_0 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 412.0
PYH1_k127_1140556_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 310.0
PYH1_k127_1140556_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000002708 239.0
PYH1_k127_1140556_3 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000001443 227.0
PYH1_k127_1140556_4 - - - - 0.0000000000000000000000000000005282 135.0
PYH1_k127_1140556_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000003538 121.0
PYH1_k127_1140556_6 Helix-turn-helix domain - - - 0.0000000002832 64.0
PYH1_k127_1140556_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000385 69.0
PYH1_k127_1165983_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005461 233.0
PYH1_k127_1165983_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008676 235.0
PYH1_k127_116875_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 395.0
PYH1_k127_116875_1 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 367.0
PYH1_k127_116875_10 Cytochrome C assembly protein - - - 0.00000001055 57.0
PYH1_k127_116875_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000002223 67.0
PYH1_k127_116875_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 296.0
PYH1_k127_116875_3 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001543 294.0
PYH1_k127_116875_4 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000002895 215.0
PYH1_k127_116875_5 denitrification pathway - - - 0.000000000000000000000000005047 118.0
PYH1_k127_116875_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000002626 117.0
PYH1_k127_116875_7 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000001139 113.0
PYH1_k127_116875_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000001804 82.0
PYH1_k127_116875_9 - - - - 0.0000000002696 74.0
PYH1_k127_1176797_0 Belongs to the peptidase S16 family - - - 2.702e-246 784.0
PYH1_k127_1176797_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.234e-230 738.0
PYH1_k127_1176797_10 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000005645 205.0
PYH1_k127_1176797_11 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000004731 161.0
PYH1_k127_1176797_12 cyclic nucleotide-binding K10914 - - 0.0000000000000000001249 92.0
PYH1_k127_1176797_13 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000001283 91.0
PYH1_k127_1176797_14 Universal stress protein family - - - 0.0000000000000003875 94.0
PYH1_k127_1176797_15 PIN domain - - - 0.000000000000007002 81.0
PYH1_k127_1176797_16 - - - - 0.000000000007941 77.0
PYH1_k127_1176797_17 ribonuclease activity - GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.0000000004148 69.0
PYH1_k127_1176797_18 Redoxin - - - 0.000000001296 68.0
PYH1_k127_1176797_19 PAS domain - - - 0.000182 49.0
PYH1_k127_1176797_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 442.0
PYH1_k127_1176797_20 AbrB family - - - 0.0002532 48.0
PYH1_k127_1176797_3 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 432.0
PYH1_k127_1176797_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 392.0
PYH1_k127_1176797_5 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 392.0
PYH1_k127_1176797_6 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 357.0
PYH1_k127_1176797_7 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 309.0
PYH1_k127_1176797_8 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000176 284.0
PYH1_k127_1176797_9 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002388 233.0
PYH1_k127_1231100_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 337.0
PYH1_k127_1231100_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000002212 175.0
PYH1_k127_1231100_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000003235 161.0
PYH1_k127_1231100_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000008711 99.0
PYH1_k127_1241690_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 454.0
PYH1_k127_1241690_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000001588 166.0
PYH1_k127_1241690_3 nucleic-acid-binding protein contains PIN domain - - - 0.0000000000000000000000000001469 123.0
PYH1_k127_1241690_4 Antidote-toxin recognition MazE, bacterial antitoxin - - - 0.000000000006256 69.0
PYH1_k127_1247359_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1323.0
PYH1_k127_1247359_1 Phosphoglucose isomerase K01810 - 5.3.1.9 5.93e-280 896.0
PYH1_k127_1247359_10 nuclease activity K06218 - - 0.000000000000000000001114 96.0
PYH1_k127_1247359_11 - - - - 0.00000000000000008308 82.0
PYH1_k127_1247359_12 Belongs to the SEDS family - - - 0.0000000002002 62.0
PYH1_k127_1247359_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 7.443e-270 839.0
PYH1_k127_1247359_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.94e-215 680.0
PYH1_k127_1247359_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 535.0
PYH1_k127_1247359_5 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 500.0
PYH1_k127_1247359_6 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 429.0
PYH1_k127_1247359_7 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 391.0
PYH1_k127_1247359_8 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 323.0
PYH1_k127_1247359_9 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 293.0
PYH1_k127_1267794_0 Sortilin, neurotensin receptor 3, - - - 2.34e-307 970.0
PYH1_k127_1267794_1 peptidyl-tyrosine sulfation - - - 4.385e-219 701.0
PYH1_k127_1267794_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 550.0
PYH1_k127_1267794_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 524.0
PYH1_k127_1267794_4 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 311.0
PYH1_k127_1267794_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000001799 265.0
PYH1_k127_1267794_6 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000297 247.0
PYH1_k127_1267794_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000373 192.0
PYH1_k127_1283871_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000001996 215.0
PYH1_k127_1283871_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000005874 187.0
PYH1_k127_1283871_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000952 198.0
PYH1_k127_1283871_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000004565 150.0
PYH1_k127_1283871_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000002054 65.0
PYH1_k127_1283871_5 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000001539 60.0
PYH1_k127_1287585_0 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 478.0
PYH1_k127_1287585_1 - - - - 0.00000000000000000000000000000000000000000003134 167.0
PYH1_k127_1287585_2 Nucleotidyl transferase - - - 0.0000000000009878 81.0
PYH1_k127_1287585_3 OsmC-like protein - - - 0.00000004412 64.0
PYH1_k127_1315326_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.801e-253 826.0
PYH1_k127_1315326_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 353.0
PYH1_k127_1315326_2 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 315.0
PYH1_k127_1315326_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000007012 230.0
PYH1_k127_1315326_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000002887 189.0
PYH1_k127_1315326_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000001496 133.0
PYH1_k127_1315326_6 Outer membrane lipoprotein - - - 0.0000000000000000000000001087 111.0
PYH1_k127_1315326_7 Lipopolysaccharide-assembly - - - 0.00000000000000004578 97.0
PYH1_k127_1315326_8 Binds directly to 16S ribosomal RNA K02968 - - 0.0000007311 57.0
PYH1_k127_1333506_0 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 461.0
PYH1_k127_1333506_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 349.0
PYH1_k127_1333506_10 - - - - 0.0000000000000001508 81.0
PYH1_k127_1333506_11 - - - - 0.00000000001573 76.0
PYH1_k127_1333506_12 GDSL-like Lipase/Acylhydrolase family - - - 0.00000002494 65.0
PYH1_k127_1333506_2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 337.0
PYH1_k127_1333506_3 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005158 275.0
PYH1_k127_1333506_4 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000001374 194.0
PYH1_k127_1333506_5 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000007427 160.0
PYH1_k127_1333506_6 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000004084 121.0
PYH1_k127_1333506_7 PIN domain - - - 0.0000000000000000000000004738 110.0
PYH1_k127_1333506_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000046 113.0
PYH1_k127_1333506_9 Protein of unknown function, DUF547 - - - 0.00000000000000000002442 101.0
PYH1_k127_1350816_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 503.0
PYH1_k127_1350816_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
PYH1_k127_1350816_2 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.00000000000000000000000000000000000000000000000000001197 211.0
PYH1_k127_1350816_3 peptidyl-tyrosine sulfation - - - 0.000000495 62.0
PYH1_k127_1392977_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 605.0
PYH1_k127_1392977_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000005777 141.0
PYH1_k127_1417569_0 B12 binding domain K04034 - 1.21.98.3 6.347e-210 665.0
PYH1_k127_1417569_1 radical SAM domain protein K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 555.0
PYH1_k127_1417569_10 methyltransferase K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000002771 173.0
PYH1_k127_1417569_11 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000773 160.0
PYH1_k127_1417569_12 Carboxypeptidase regulatory-like domain - - - 0.000000000000000003418 101.0
PYH1_k127_1417569_13 Uncharacterised nucleotidyltransferase - - - 0.0000000239 68.0
PYH1_k127_1417569_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 531.0
PYH1_k127_1417569_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 476.0
PYH1_k127_1417569_4 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 387.0
PYH1_k127_1417569_5 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 374.0
PYH1_k127_1417569_6 Hexosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 306.0
PYH1_k127_1417569_7 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 302.0
PYH1_k127_1417569_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000006429 216.0
PYH1_k127_1417569_9 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000002633 207.0
PYH1_k127_1426967_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 516.0
PYH1_k127_1426967_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 411.0
PYH1_k127_1426967_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000025 231.0
PYH1_k127_1426967_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000004922 209.0
PYH1_k127_1426967_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000008149 168.0
PYH1_k127_143500_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 317.0
PYH1_k127_143500_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 293.0
PYH1_k127_143500_2 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006224 264.0
PYH1_k127_143500_3 TOBE domain K02017,K06857 - 3.6.3.29,3.6.3.55 0.000000000000000000000000000000009192 141.0
PYH1_k127_1438695_0 PFAM Amidase - - - 8.305e-271 840.0
PYH1_k127_1438695_1 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 520.0
PYH1_k127_1438695_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001814 51.0
PYH1_k127_1497627_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 535.0
PYH1_k127_1497627_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 335.0
PYH1_k127_1551633_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.302e-258 810.0
PYH1_k127_1551633_1 response regulator - - - 1.473e-255 827.0
PYH1_k127_1551633_10 Predicted membrane protein (DUF2232) - - - 0.000000001473 67.0
PYH1_k127_1551633_2 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 523.0
PYH1_k127_1551633_3 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 529.0
PYH1_k127_1551633_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 424.0
PYH1_k127_1551633_5 transcriptional regulator K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 356.0
PYH1_k127_1551633_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004988 224.0
PYH1_k127_1551633_7 nuclease activity K18828 - - 0.00000000000000000000000000000000000005539 146.0
PYH1_k127_1551633_8 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000001554 137.0
PYH1_k127_1551633_9 - K21495 - - 0.00000000000000000006548 91.0
PYH1_k127_1573614_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 593.0
PYH1_k127_1573614_1 signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 504.0
PYH1_k127_1573614_2 radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 397.0
PYH1_k127_1573614_3 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
PYH1_k127_1573614_4 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005641 267.0
PYH1_k127_1573614_5 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000000009803 185.0
PYH1_k127_1573614_6 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000008513 125.0
PYH1_k127_1573614_7 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000001118 100.0
PYH1_k127_1573614_8 aminopeptidase N - - - 0.000000000000407 81.0
PYH1_k127_1573614_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00001184 51.0
PYH1_k127_1622921_0 Malate synthase K01638 - 2.3.3.9 0.0 1166.0
PYH1_k127_1622921_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 514.0
PYH1_k127_1622921_10 stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000001188 132.0
PYH1_k127_1622921_11 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000001024 123.0
PYH1_k127_1622921_12 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000004869 88.0
PYH1_k127_1622921_13 Baseplate assembly protein - - - 0.0000000000000001093 83.0
PYH1_k127_1622921_14 carboxylic ester hydrolase activity - - - 0.0000000000000005452 87.0
PYH1_k127_1622921_15 - - - - 0.0000000000000009799 86.0
PYH1_k127_1622921_16 - - - - 0.0000000000001017 76.0
PYH1_k127_1622921_17 - - - - 0.0000000002832 65.0
PYH1_k127_1622921_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 419.0
PYH1_k127_1622921_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 401.0
PYH1_k127_1622921_4 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 375.0
PYH1_k127_1622921_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 380.0
PYH1_k127_1622921_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 380.0
PYH1_k127_1622921_7 - - - - 0.0000000000000000000000000000000000000000000000000000000003585 206.0
PYH1_k127_1622921_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000004919 208.0
PYH1_k127_1622921_9 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000002864 185.0
PYH1_k127_1638858_0 B12 binding domain - - - 2.312e-248 776.0
PYH1_k127_1638858_1 Radical SAM - - - 1.81e-203 671.0
PYH1_k127_1638858_2 Polyphosphate kinase middle domain K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 598.0
PYH1_k127_1638858_3 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 269.0
PYH1_k127_1638858_4 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.00000000000000000000000000000000000000005794 158.0
PYH1_k127_1638858_5 Glutaredoxin K03676 - - 0.00000003778 56.0
PYH1_k127_1638858_6 lysyltransferase activity K07027 - - 0.0000002684 59.0
PYH1_k127_1638858_7 CAAX protease self-immunity - - - 0.0007872 51.0
PYH1_k127_1680160_0 PFAM peptidase M13 K07386 - - 2.575e-225 721.0
PYH1_k127_1680160_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 430.0
PYH1_k127_1680160_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004722 264.0
PYH1_k127_1680160_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000001543 257.0
PYH1_k127_1680160_4 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000003599 138.0
PYH1_k127_1681890_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 8.98e-272 853.0
PYH1_k127_1681890_1 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 498.0
PYH1_k127_1681890_2 Glycosyltransferase like family 2 K00721,K20534 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 357.0
PYH1_k127_1681890_3 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 347.0
PYH1_k127_1681890_4 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 344.0
PYH1_k127_1681890_5 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000003845 205.0
PYH1_k127_1681890_6 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000006928 181.0
PYH1_k127_1681890_7 fatty acid desaturase - - - 0.00000000000425 77.0
PYH1_k127_1682121_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 457.0
PYH1_k127_1682121_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 358.0
PYH1_k127_1682121_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
PYH1_k127_1682121_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003261 296.0
PYH1_k127_1682121_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
PYH1_k127_1682121_5 Putative diguanylate phosphodiesterase K14051 - 3.1.4.52 0.00000000000000000001223 93.0
PYH1_k127_1698207_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 496.0
PYH1_k127_1698207_1 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000002963 260.0
PYH1_k127_1698207_2 Redoxin - - - 0.00000000000000000006178 102.0
PYH1_k127_1698207_3 homoserine transmembrane transporter activity - - - 0.000000007903 65.0
PYH1_k127_1707255_0 GMC oxidoreductase K03333 - 1.1.3.6 8.76e-228 717.0
PYH1_k127_1707255_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.087e-202 647.0
PYH1_k127_1707255_10 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000006826 136.0
PYH1_k127_1707255_11 AraC-like ligand binding domain - - - 0.00000000000000000000000000000001531 134.0
PYH1_k127_1707255_12 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000001899 126.0
PYH1_k127_1707255_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 594.0
PYH1_k127_1707255_3 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 524.0
PYH1_k127_1707255_4 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 450.0
PYH1_k127_1707255_5 PFAM sodium calcium exchanger membrane region K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 418.0
PYH1_k127_1707255_6 Tyrosine 3-monooxygenase K00501 GO:0000003,GO:0001101,GO:0001654,GO:0001666,GO:0001678,GO:0001754,GO:0001963,GO:0001975,GO:0002237,GO:0003007,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004511,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005783,GO:0005790,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006570,GO:0006584,GO:0006585,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006720,GO:0006725,GO:0006807,GO:0006810,GO:0006836,GO:0006950,GO:0006970,GO:0007154,GO:0007267,GO:0007268,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007444,GO:0007507,GO:0007564,GO:0007568,GO:0007591,GO:0007593,GO:0007600,GO:0007601,GO:0007605,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007617,GO:0007618,GO:0007619,GO:0007622,GO:0007623,GO:0007626,GO:0007631,GO:0007638,GO:0008016,GO:0008021,GO:0008049,GO:0008144,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0008344,GO:0009058,GO:0009072,GO:0009266,GO:0009314,GO:0009404,GO:0009410,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009612,GO:0009617,GO:0009628,GO:0009635,GO:0009636,GO:0009651,GO:0009653,GO:0009712,GO:0009713,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009820,GO:0009887,GO:0009888,GO:0009898,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010043,GO:0010243,GO:0010259,GO:0010632,GO:0012505,GO:0012506,GO:0014070,GO:0014075,GO:0014823,GO:0015837,GO:0015842,GO:0016020,GO:0016043,GO:0016137,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017085,GO:0017144,GO:0018958,GO:0018963,GO:0019098,GO:0019438,GO:0019725,GO:0019748,GO:0019752,GO:0019825,GO:0019899,GO:0019904,GO:0019953,GO:0021537,GO:0021543,GO:0021700,GO:0021987,GO:0022008,GO:0022404,GO:0022414,GO:0022607,GO:0023052,GO:0030133,GO:0030154,GO:0030182,GO:0030334,GO:0030424,GO:0030425,GO:0030534,GO:0030659,GO:0030900,GO:0031076,GO:0031090,GO:0031406,GO:0031410,GO:0031667,GO:0031960,GO:0031982,GO:0032094,GO:0032355,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032879,GO:0033076,GO:0033162,GO:0033267,GO:0033500,GO:0033993,GO:0034284,GO:0034607,GO:0034617,GO:0034641,GO:0035094,GO:0035176,GO:0035178,GO:0035220,GO:0035240,GO:0035295,GO:0035690,GO:0035900,GO:0035902,GO:0036094,GO:0036293,GO:0036477,GO:0040011,GO:0040012,GO:0040040,GO:0042214,GO:0042221,GO:0042303,GO:0042330,GO:0042335,GO:0042414,GO:0042415,GO:0042416,GO:0042417,GO:0042418,GO:0042421,GO:0042423,GO:0042461,GO:0042462,GO:0042470,GO:0042493,GO:0042537,GO:0042592,GO:0042593,GO:0042745,GO:0042755,GO:0042995,GO:0043005,GO:0043010,GO:0043025,GO:0043052,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043195,GO:0043204,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043279,GO:0043434,GO:0043436,GO:0043473,GO:0043648,GO:0043679,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0045009,GO:0045202,GO:0045471,GO:0045472,GO:0046189,GO:0046483,GO:0046530,GO:0046677,GO:0046684,GO:0046872,GO:0046914,GO:0046958,GO:0046959,GO:0048037,GO:0048048,GO:0048066,GO:0048067,GO:0048070,GO:0048079,GO:0048082,GO:0048085,GO:0048468,GO:0048511,GO:0048512,GO:0048513,GO:0048545,GO:0048562,GO:0048568,GO:0048592,GO:0048593,GO:0048596,GO:0048598,GO:0048609,GO:0048666,GO:0048699,GO:0048731,GO:0048770,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0050953,GO:0050954,GO:0051179,GO:0051234,GO:0051239,GO:0051259,GO:0051260,GO:0051262,GO:0051270,GO:0051289,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051649,GO:0051703,GO:0051704,GO:0051705,GO:0051707,GO:0051716,GO:0052314,GO:0055082,GO:0055114,GO:0060179,GO:0060322,GO:0060429,GO:0065003,GO:0065007,GO:0065008,GO:0070382,GO:0070405,GO:0070482,GO:0070848,GO:0070887,GO:0071241,GO:0071248,GO:0071287,GO:0071310,GO:0071312,GO:0071316,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071363,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072359,GO:0090596,GO:0090741,GO:0097159,GO:0097164,GO:0097237,GO:0097305,GO:0097366,GO:0097447,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098700,GO:0098793,GO:0098805,GO:0098916,GO:0099503,GO:0099504,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0150034,GO:1901135,GO:1901338,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901615,GO:1901617,GO:1901652,GO:1901654,GO:1901657,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903522,GO:2000026,GO:2000145,GO:2000274 1.14.16.2 0.00000000000000000000000000000000000000000000000000000000000003144 226.0
PYH1_k127_1707255_7 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
PYH1_k127_1707255_8 - - - - 0.000000000000000000000000000000000000002981 161.0
PYH1_k127_1707255_9 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000006686 152.0
PYH1_k127_1730130_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.092e-215 677.0
PYH1_k127_1730130_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 602.0
PYH1_k127_1730130_2 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 444.0
PYH1_k127_1730130_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000004568 210.0
PYH1_k127_1730130_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000006341 123.0
PYH1_k127_17325_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 564.0
PYH1_k127_17325_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 388.0
PYH1_k127_17325_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000003968 273.0
PYH1_k127_17325_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
PYH1_k127_17325_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000005581 119.0
PYH1_k127_17325_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000001881 123.0
PYH1_k127_1742879_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1289.0
PYH1_k127_1742879_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1060.0
PYH1_k127_1742879_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 325.0
PYH1_k127_1742879_3 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
PYH1_k127_1742879_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000001429 107.0
PYH1_k127_1785253_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.228e-237 745.0
PYH1_k127_1785253_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 335.0
PYH1_k127_1785253_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 299.0
PYH1_k127_1785253_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000001425 233.0
PYH1_k127_1785253_4 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000001183 134.0
PYH1_k127_1785253_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000001354 95.0
PYH1_k127_1785253_6 ABC transporter K01990 - - 0.0000000000000001507 91.0
PYH1_k127_1796950_0 ImcF-related N-terminal domain K11891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 304.0
PYH1_k127_1796950_1 TIGRFAM type VI secretion protein, VC_A0114 family K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000303 240.0
PYH1_k127_1796950_2 Type VI secretion system protein DotU - - - 0.00000004357 63.0
PYH1_k127_1799127_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 556.0
PYH1_k127_1799127_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 490.0
PYH1_k127_1799127_10 Transcription factor zinc-finger - - - 0.000000000000000000000000000001154 136.0
PYH1_k127_1799127_11 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000003541 125.0
PYH1_k127_1799127_12 holo-[acyl-carrier-protein] synthase activity K00997,K01207 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 0.0000000000000000000000419 104.0
PYH1_k127_1799127_13 PFAM Sensors of blue-light using FAD - - - 0.0000000000000000008694 91.0
PYH1_k127_1799127_14 Stage II sporulation D domain protein K06381 - - 0.00000000000000001535 97.0
PYH1_k127_1799127_16 acyl carrier protein - - - 0.000000001015 62.0
PYH1_k127_1799127_17 His Kinase A (phosphoacceptor) domain - - - 0.000000007105 69.0
PYH1_k127_1799127_2 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 469.0
PYH1_k127_1799127_3 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 406.0
PYH1_k127_1799127_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 368.0
PYH1_k127_1799127_5 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 330.0
PYH1_k127_1799127_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000001994 185.0
PYH1_k127_1799127_8 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.000000000000000000000000000000000000000001045 167.0
PYH1_k127_1799127_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001034 164.0
PYH1_k127_1817116_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003839 293.0
PYH1_k127_1817116_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 277.0
PYH1_k127_1817116_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001074 208.0
PYH1_k127_1817116_3 Membrane - - - 0.0000000000001018 84.0
PYH1_k127_1884070_0 Biogenesis protein - - - 0.00000000000000000000000000000000001415 144.0
PYH1_k127_1884070_1 diguanylate cyclase - - - 0.00000000000000000000000000000000006703 138.0
PYH1_k127_1884070_2 LAO AO transport system ATPase K07588 - - 0.000000000000000000000001506 116.0
PYH1_k127_1884070_3 ArgK protein K07588 - - 0.0000000000000005499 79.0
PYH1_k127_1884984_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 398.0
PYH1_k127_1884984_1 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 305.0
PYH1_k127_1884984_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000001392 87.0
PYH1_k127_1884984_11 Protein of unknown function (DUF1573) - - - 0.00000000000003336 86.0
PYH1_k127_1884984_12 oligosaccharyl transferase activity - - - 0.00000005499 62.0
PYH1_k127_1884984_2 of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006818 271.0
PYH1_k127_1884984_3 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001436 262.0
PYH1_k127_1884984_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000006702 231.0
PYH1_k127_1884984_5 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000576 189.0
PYH1_k127_1884984_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000001033 168.0
PYH1_k127_1884984_7 Fibronectin, type III domain - - - 0.000000000000000000001457 109.0
PYH1_k127_1884984_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000001769 110.0
PYH1_k127_1884984_9 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000009817 96.0
PYH1_k127_1959447_0 PFAM ribonuclease II K01147 - 3.1.13.1 3.477e-194 617.0
PYH1_k127_1959447_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 299.0
PYH1_k127_1959447_2 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.00000000000000000000000005832 108.0
PYH1_k127_1959447_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000005627 69.0
PYH1_k127_2033112_0 Belongs to the UPF0441 family - - - 3.515e-203 664.0
PYH1_k127_2033112_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 383.0
PYH1_k127_2033112_2 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 327.0
PYH1_k127_2033112_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000003179 109.0
PYH1_k127_2033112_4 Ankyrin 1, erythrocytic K10380 GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006887,GO:0006888,GO:0006996,GO:0007010,GO:0007163,GO:0007275,GO:0008092,GO:0008093,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010638,GO:0012505,GO:0014731,GO:0015672,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016528,GO:0016529,GO:0018130,GO:0019438,GO:0019899,GO:0030011,GO:0030016,GO:0030017,GO:0030018,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030424,GO:0030507,GO:0030673,GO:0030674,GO:0030863,GO:0031252,GO:0031253,GO:0031256,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032589,GO:0032940,GO:0033013,GO:0033014,GO:0033036,GO:0033043,GO:0033267,GO:0034101,GO:0034613,GO:0034641,GO:0035088,GO:0035090,GO:0042383,GO:0042592,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0044237,GO:0044249,GO:0044271,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045197,GO:0045199,GO:0045202,GO:0045211,GO:0046483,GO:0046903,GO:0046907,GO:0048193,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060090,GO:0061245,GO:0061515,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0097060,GO:0097458,GO:0098590,GO:0098771,GO:0098794,GO:0099080,GO:0099081,GO:0099512,GO:0099568,GO:0120025,GO:0120038,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1990778 - 0.0000000000000000002208 98.0
PYH1_k127_2033112_5 - - - - 0.00000000000000001185 87.0
PYH1_k127_2033112_6 protein ubiquitination K15502 - - 0.000000000002867 79.0
PYH1_k127_2033112_8 PFAM plasmid stabilization system K06218 - - 0.0000001454 55.0
PYH1_k127_205240_0 HlyD membrane-fusion protein of T1SS K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 496.0
PYH1_k127_205240_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 422.0
PYH1_k127_205240_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 424.0
PYH1_k127_205240_3 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 366.0
PYH1_k127_205240_4 Metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 308.0
PYH1_k127_205240_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000008493 169.0
PYH1_k127_205240_6 PFAM Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000000009246 169.0
PYH1_k127_205240_7 - - - - 0.000000000000000002148 90.0
PYH1_k127_2097092_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.056e-234 732.0
PYH1_k127_2097092_1 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000726 138.0
PYH1_k127_2097092_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000005999 83.0
PYH1_k127_2105057_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
PYH1_k127_2105057_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000102 255.0
PYH1_k127_2105057_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.00000000000000000000000000000000000001918 164.0
PYH1_k127_2105057_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000003562 80.0
PYH1_k127_2105057_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000003116 76.0
PYH1_k127_2108717_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 262.0
PYH1_k127_2108717_1 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001199 245.0
PYH1_k127_2108717_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000003817 141.0
PYH1_k127_2115329_0 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 422.0
PYH1_k127_2115329_1 Metal-dependent phosphoesterase K07053 - 3.1.3.97 0.000000000000000004608 87.0
PYH1_k127_2115329_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000002194 70.0
PYH1_k127_2115329_3 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000009252 51.0
PYH1_k127_2159093_0 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 378.0
PYH1_k127_2159093_1 Major royal jelly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 334.0
PYH1_k127_2159093_2 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006884 289.0
PYH1_k127_2159093_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001515 277.0
PYH1_k127_2159093_4 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000415 267.0
PYH1_k127_2159093_5 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000000000000000000000000007304 151.0
PYH1_k127_2178671_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 395.0
PYH1_k127_2178671_1 - - - - 0.0000000007098 67.0
PYH1_k127_2232868_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 547.0
PYH1_k127_2232868_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 511.0
PYH1_k127_2232868_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
PYH1_k127_2232868_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000003243 228.0
PYH1_k127_2232868_4 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000001129 229.0
PYH1_k127_2232868_5 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000001782 151.0
PYH1_k127_2251908_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
PYH1_k127_2251908_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004727 279.0
PYH1_k127_2251908_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000004398 190.0
PYH1_k127_2251908_3 structural constituent of ribosome K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000769 162.0
PYH1_k127_2251908_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0001521 55.0
PYH1_k127_2269894_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 610.0
PYH1_k127_2269894_1 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 435.0
PYH1_k127_2269894_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004956 296.0
PYH1_k127_2269894_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000044 173.0
PYH1_k127_2269894_4 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0032501,GO:0036211,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0046872,GO:0046914,GO:0048871,GO:0050897,GO:0065007,GO:0065008,GO:0071704,GO:0097009,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000004455 178.0
PYH1_k127_2269894_5 Including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000007716 154.0
PYH1_k127_2269894_6 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000002322 108.0
PYH1_k127_2269894_7 Membrane - - - 0.00000000000000000002947 106.0
PYH1_k127_2269894_8 Protein of unknown function, DUF255 K01829 - 5.3.4.1 0.0000000000003384 76.0
PYH1_k127_2276584_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 414.0
PYH1_k127_2276584_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 391.0
PYH1_k127_2276584_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 342.0
PYH1_k127_2276584_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 340.0
PYH1_k127_2276584_4 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000163 304.0
PYH1_k127_2276584_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000102 142.0
PYH1_k127_2283715_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 617.0
PYH1_k127_2283715_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 480.0
PYH1_k127_2283715_2 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 340.0
PYH1_k127_2283715_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001374 303.0
PYH1_k127_2283715_4 Chromate resistance exported protein - - - 0.0000000000003406 78.0
PYH1_k127_2289575_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 579.0
PYH1_k127_2289575_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 554.0
PYH1_k127_2289575_10 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000002146 203.0
PYH1_k127_2289575_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000003809 165.0
PYH1_k127_2289575_12 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.0000000000000000000000000000000000000006244 150.0
PYH1_k127_2289575_13 - - - - 0.00000000000000000000000000000000005577 140.0
PYH1_k127_2289575_14 - - - - 0.000000000000000000000000000000006623 137.0
PYH1_k127_2289575_15 DinB family - - - 0.00000000000000000000000000000000726 134.0
PYH1_k127_2289575_16 transposition - - - 0.0000000000000000000000000000000103 131.0
PYH1_k127_2289575_17 Cytochrome c554 and c-prime - - - 0.00000000000000000000000001522 120.0
PYH1_k127_2289575_18 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000008645 113.0
PYH1_k127_2289575_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 457.0
PYH1_k127_2289575_3 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 472.0
PYH1_k127_2289575_4 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 424.0
PYH1_k127_2289575_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 338.0
PYH1_k127_2289575_6 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 337.0
PYH1_k127_2289575_7 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
PYH1_k127_2289575_8 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000043 297.0
PYH1_k127_2289575_9 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000005378 227.0
PYH1_k127_2366270_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1149.0
PYH1_k127_2366270_1 Carbamoyltransferase C-terminus K00612 - - 1.242e-258 811.0
PYH1_k127_2366270_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 1.099e-243 758.0
PYH1_k127_2366270_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 3.563e-225 702.0
PYH1_k127_2366270_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 5.523e-195 621.0
PYH1_k127_2366270_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 546.0
PYH1_k127_2366270_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000019 129.0
PYH1_k127_2366270_7 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000001211 68.0
PYH1_k127_2366965_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.349e-260 828.0
PYH1_k127_2366965_1 Peptide transporter - - - 1.44e-212 680.0
PYH1_k127_2366965_10 homoserine transmembrane transporter activity K06600,K06895 - - 0.000000000000000000000000000000000005158 145.0
PYH1_k127_2366965_11 HupF/HypC family K04653 - - 0.000000000000000000012 96.0
PYH1_k127_2366965_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 581.0
PYH1_k127_2366965_3 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 534.0
PYH1_k127_2366965_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 436.0
PYH1_k127_2366965_5 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 336.0
PYH1_k127_2366965_6 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002026 289.0
PYH1_k127_2366965_7 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000007117 251.0
PYH1_k127_2366965_8 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000002022 190.0
PYH1_k127_2366965_9 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000007308 142.0
PYH1_k127_2387583_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 554.0
PYH1_k127_2387583_1 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.00000000000000000000000000000000000000000000000000000000000000002053 235.0
PYH1_k127_2387583_2 Mitochondrial biogenesis AIM24 - - - 0.000000000214 73.0
PYH1_k127_240340_0 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 467.0
PYH1_k127_240340_1 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005136 283.0
PYH1_k127_2403962_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 430.0
PYH1_k127_2403962_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 375.0
PYH1_k127_2403962_2 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 340.0
PYH1_k127_2403962_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 324.0
PYH1_k127_2403962_4 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000243 293.0
PYH1_k127_2403962_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001144 278.0
PYH1_k127_2403962_6 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000002635 254.0
PYH1_k127_2403962_7 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000002228 152.0
PYH1_k127_2403962_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000113 134.0
PYH1_k127_2446632_0 PFAM Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009691 267.0
PYH1_k127_2446632_1 Ferritin Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000334 245.0
PYH1_k127_2446632_2 acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000001447 141.0
PYH1_k127_2446632_3 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000009466 83.0
PYH1_k127_2446632_4 Protein tyrosine kinase - - - 0.0000000000000002054 81.0
PYH1_k127_2446632_5 Outer membrane efflux protein - - - 0.000000001733 69.0
PYH1_k127_2514463_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 609.0
PYH1_k127_2514463_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 584.0
PYH1_k127_2514463_2 Leukotriene A4 hydrolase, C-terminal K01254 GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 534.0
PYH1_k127_2514463_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 313.0
PYH1_k127_2514463_4 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000001511 127.0
PYH1_k127_2514463_5 - - - - 0.0000000000000000000000003605 121.0
PYH1_k127_2514463_6 Peptidase family M28 - - - 0.000000000000000000004842 108.0
PYH1_k127_2514463_7 SPFH domain-Band 7 family - - - 0.0000000000000348 83.0
PYH1_k127_2514463_8 CBS domain K04767 - - 0.000000000007055 71.0
PYH1_k127_2545110_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 631.0
PYH1_k127_2545110_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 566.0
PYH1_k127_2545110_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 286.0
PYH1_k127_2545110_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000431 276.0
PYH1_k127_2560808_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 585.0
PYH1_k127_2560808_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000003039 218.0
PYH1_k127_2560808_2 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000006045 204.0
PYH1_k127_2560808_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000003777 146.0
PYH1_k127_2560808_4 lysyltransferase activity K07027 - - 0.0000000000001002 76.0
PYH1_k127_2560808_5 peptidyl-tyrosine sulfation - - - 0.0001999 50.0
PYH1_k127_2569100_0 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.167e-198 631.0
PYH1_k127_2569100_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 561.0
PYH1_k127_2569100_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000007201 247.0
PYH1_k127_2569100_11 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000009781 89.0
PYH1_k127_2569100_12 Peptidase M56 - - - 0.0000000002217 73.0
PYH1_k127_2569100_13 Amidohydrolase family - - - 0.0000000002569 73.0
PYH1_k127_2569100_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000007992 63.0
PYH1_k127_2569100_15 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000002637 54.0
PYH1_k127_2569100_16 Domain of unknown function (DUF4388) - - - 0.0000003784 63.0
PYH1_k127_2569100_17 oxidoreductase activity - - - 0.00006737 57.0
PYH1_k127_2569100_2 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 528.0
PYH1_k127_2569100_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 505.0
PYH1_k127_2569100_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 451.0
PYH1_k127_2569100_5 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 426.0
PYH1_k127_2569100_6 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 413.0
PYH1_k127_2569100_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 383.0
PYH1_k127_2569100_8 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001394 291.0
PYH1_k127_2569100_9 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000001725 242.0
PYH1_k127_2598451_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000001146 182.0
PYH1_k127_2598451_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000001058 143.0
PYH1_k127_2599741_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 314.0
PYH1_k127_2599741_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000002004 200.0
PYH1_k127_2599741_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000007239 126.0
PYH1_k127_2599741_3 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000508 89.0
PYH1_k127_2599883_0 filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 511.0
PYH1_k127_2599883_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 463.0
PYH1_k127_2599883_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 305.0
PYH1_k127_2599883_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003639 243.0
PYH1_k127_2599883_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000004586 237.0
PYH1_k127_2599883_6 cellulose binding - - - 0.000000000000000001198 99.0
PYH1_k127_2608226_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 426.0
PYH1_k127_2608226_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001001 278.0
PYH1_k127_2608226_2 ATPase involved in DNA repair - - - 0.0000001953 60.0
PYH1_k127_2608773_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000006549 216.0
PYH1_k127_2610093_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 3.606e-244 764.0
PYH1_k127_2610093_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 467.0
PYH1_k127_2610093_2 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000000239 162.0
PYH1_k127_2610093_3 - - - - 0.00000000000000000000000000000000000004092 151.0
PYH1_k127_2610093_4 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000004828 143.0
PYH1_k127_2610093_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000001322 108.0
PYH1_k127_2610093_6 regulator - - - 0.0000000000000000000000508 104.0
PYH1_k127_2610093_7 aspartate kinase activity - - - 0.0000000001028 68.0
PYH1_k127_2610093_8 Pfam Response regulator receiver - - - 0.000000001079 63.0
PYH1_k127_2616383_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.722e-236 751.0
PYH1_k127_2616383_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 356.0
PYH1_k127_2616383_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 343.0
PYH1_k127_2616383_3 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
PYH1_k127_2616383_4 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000002353 110.0
PYH1_k127_2616383_5 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000004402 78.0
PYH1_k127_2616383_6 Methyltransferase domain - - - 0.0000000000003077 81.0
PYH1_k127_2616383_7 PFAM Fimbrial assembly family protein K02663 - - 0.000000007817 64.0
PYH1_k127_2621225_0 Sortilin, neurotensin receptor 3, - - - 0.0 1225.0
PYH1_k127_2621225_1 cellulose binding - - - 7.12e-263 844.0
PYH1_k127_2621225_10 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 431.0
PYH1_k127_2621225_11 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 427.0
PYH1_k127_2621225_12 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 384.0
PYH1_k127_2621225_13 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
PYH1_k127_2621225_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 342.0
PYH1_k127_2621225_15 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 314.0
PYH1_k127_2621225_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006352 243.0
PYH1_k127_2621225_17 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000001296 238.0
PYH1_k127_2621225_18 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000006656 222.0
PYH1_k127_2621225_19 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000564 219.0
PYH1_k127_2621225_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 7.883e-231 726.0
PYH1_k127_2621225_20 DinB family - - - 0.00000000000000000000000000000005089 142.0
PYH1_k127_2621225_21 RNA recognition motif - - - 0.0000000000000000000002115 103.0
PYH1_k127_2621225_22 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000008206 101.0
PYH1_k127_2621225_23 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000001755 93.0
PYH1_k127_2621225_24 ACT domain K01653 - 2.2.1.6 0.0000003193 56.0
PYH1_k127_2621225_3 Dehydratase family K01687 - 4.2.1.9 3.594e-223 706.0
PYH1_k127_2621225_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 4.979e-210 677.0
PYH1_k127_2621225_5 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 563.0
PYH1_k127_2621225_6 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 509.0
PYH1_k127_2621225_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 481.0
PYH1_k127_2621225_8 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 487.0
PYH1_k127_2621225_9 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 434.0
PYH1_k127_2626103_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 503.0
PYH1_k127_2626103_1 GAF domain - - - 0.000000000000000000000000000000000000000107 165.0
PYH1_k127_2626103_2 endoglucanase-related protein, glucosyl hydrolase family 9 protein - - - 0.00000000001008 79.0
PYH1_k127_2626103_3 Oxygen tolerance - - - 0.0004736 48.0
PYH1_k127_2626247_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 490.0
PYH1_k127_2626247_1 Cupin 2, conserved barrel domain protein K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000272 251.0
PYH1_k127_2626247_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000003572 226.0
PYH1_k127_2626247_3 PIN domain - - - 0.00000000000000000000000000000000000000004403 158.0
PYH1_k127_2626247_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000008298 111.0
PYH1_k127_2626247_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000002596 99.0
PYH1_k127_2627043_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 447.0
PYH1_k127_2627043_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 377.0
PYH1_k127_2627043_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001121 280.0
PYH1_k127_2627043_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000001054 216.0
PYH1_k127_2627043_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000003079 143.0
PYH1_k127_2627043_5 Response regulator receiver domain - - - 0.00000000002965 76.0
PYH1_k127_2638531_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 602.0
PYH1_k127_2638531_1 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
PYH1_k127_2638531_10 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000003461 134.0
PYH1_k127_2638531_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001812 136.0
PYH1_k127_2638531_12 Pas domain - - - 0.0000000000000000000001708 107.0
PYH1_k127_2638531_13 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000002806 89.0
PYH1_k127_2638531_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000003281 76.0
PYH1_k127_2638531_2 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 501.0
PYH1_k127_2638531_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 323.0
PYH1_k127_2638531_4 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008824 287.0
PYH1_k127_2638531_5 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 254.0
PYH1_k127_2638531_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
PYH1_k127_2638531_7 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000005598 224.0
PYH1_k127_2638531_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000005728 192.0
PYH1_k127_2638531_9 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000007788 175.0
PYH1_k127_2646888_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.067e-280 875.0
PYH1_k127_2646888_1 DEAD DEAH box helicase - - - 8.933e-266 846.0
PYH1_k127_2646888_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000009456 239.0
PYH1_k127_2646888_11 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000001795 253.0
PYH1_k127_2646888_12 Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000002359 209.0
PYH1_k127_2646888_13 - - - - 0.000000000000000000000000000000000000000000000000000000000276 211.0
PYH1_k127_2646888_14 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000001634 224.0
PYH1_k127_2646888_15 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000002212 178.0
PYH1_k127_2646888_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000659 161.0
PYH1_k127_2646888_17 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000102 154.0
PYH1_k127_2646888_18 MlaD protein K02067 - - 0.0000000000000000000000000000000000007216 154.0
PYH1_k127_2646888_19 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000001676 143.0
PYH1_k127_2646888_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 595.0
PYH1_k127_2646888_20 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000001441 130.0
PYH1_k127_2646888_21 Dodecin K09165 - - 0.00000000000000000000000285 105.0
PYH1_k127_2646888_22 CHASE - - - 0.000000000000000000001119 111.0
PYH1_k127_2646888_23 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000003059 78.0
PYH1_k127_2646888_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 571.0
PYH1_k127_2646888_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 481.0
PYH1_k127_2646888_5 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 466.0
PYH1_k127_2646888_6 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 453.0
PYH1_k127_2646888_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 345.0
PYH1_k127_2646888_8 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 342.0
PYH1_k127_2646888_9 serine-type endopeptidase inhibitor activity K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 303.0
PYH1_k127_265056_0 ABC transporter K06020 - 3.6.3.25 1.727e-245 769.0
PYH1_k127_265056_1 Prolyl oligopeptidase family - - - 1.297e-213 684.0
PYH1_k127_265056_10 - - - - 0.00000000000000002916 96.0
PYH1_k127_265056_11 - - - - 0.0001799 49.0
PYH1_k127_265056_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 561.0
PYH1_k127_265056_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 518.0
PYH1_k127_265056_4 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 464.0
PYH1_k127_265056_5 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 326.0
PYH1_k127_265056_6 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000115 304.0
PYH1_k127_265056_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 267.0
PYH1_k127_265056_8 - - - - 0.00000000000000000000000000000000000000000000000000000008971 218.0
PYH1_k127_265056_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000003491 130.0
PYH1_k127_267108_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 500.0
PYH1_k127_267108_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 492.0
PYH1_k127_267108_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 452.0
PYH1_k127_267108_4 Putative zinc- or iron-chelating domain - - - 0.000000000000007615 85.0
PYH1_k127_267108_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00001613 51.0
PYH1_k127_2697895_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 406.0
PYH1_k127_2697895_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 358.0
PYH1_k127_2697895_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000004418 86.0
PYH1_k127_2697895_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000004664 72.0
PYH1_k127_2697895_12 Domain of unknown function (DUF4340) - - - 0.0005321 52.0
PYH1_k127_2697895_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 301.0
PYH1_k127_2697895_3 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000754 273.0
PYH1_k127_2697895_4 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000007486 236.0
PYH1_k127_2697895_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000005278 156.0
PYH1_k127_2697895_6 Hydrolase - - - 0.0000000000000000000000000000000001369 145.0
PYH1_k127_2697895_7 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000005049 115.0
PYH1_k127_2697895_8 PFAM pentapeptide repeat protein - - - 0.000000000000000000000000005932 128.0
PYH1_k127_2697895_9 EamA-like transporter family - - - 0.0000000000000000000002165 108.0
PYH1_k127_2711016_0 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 412.0
PYH1_k127_2711016_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 383.0
PYH1_k127_2711016_2 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
PYH1_k127_2711016_3 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000004536 187.0
PYH1_k127_2711016_4 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000000000000000000005418 184.0
PYH1_k127_2727372_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 8.011e-215 673.0
PYH1_k127_2727372_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 600.0
PYH1_k127_2727372_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 560.0
PYH1_k127_2727372_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 398.0
PYH1_k127_2727372_4 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 370.0
PYH1_k127_2727372_5 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000001455 251.0
PYH1_k127_2727372_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000001845 198.0
PYH1_k127_2727372_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000003649 109.0
PYH1_k127_2727372_9 Memo-like protein K06990 - - 0.00000000000000002745 85.0
PYH1_k127_2746944_0 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000004704 234.0
PYH1_k127_2748190_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 628.0
PYH1_k127_2748190_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 316.0
PYH1_k127_2748190_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 249.0
PYH1_k127_2748190_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000008498 136.0
PYH1_k127_2748190_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000001108 78.0
PYH1_k127_2755432_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 407.0
PYH1_k127_2755432_1 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 297.0
PYH1_k127_2755432_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000002808 155.0
PYH1_k127_2755432_3 Thioredoxin K03671 - - 0.000000000000000000000000000000007364 138.0
PYH1_k127_2755432_4 Psort location CytoplasmicMembrane, score - - - 0.000001231 61.0
PYH1_k127_2757677_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 348.0
PYH1_k127_2757677_1 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000008078 218.0
PYH1_k127_2757677_2 Histidine kinase - - - 0.00000000000000000000000000000000005953 150.0
PYH1_k127_2757677_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000001199 120.0
PYH1_k127_2757677_4 SPTR RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000001249 57.0
PYH1_k127_2850250_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 613.0
PYH1_k127_2850250_1 helicase superfamily c-terminal domain K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 442.0
PYH1_k127_287207_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 580.0
PYH1_k127_287207_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 394.0
PYH1_k127_287207_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 379.0
PYH1_k127_287207_3 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000003631 237.0
PYH1_k127_287207_4 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000009778 139.0
PYH1_k127_287207_5 PQ loop repeat K15383 - - 0.00000002683 67.0
PYH1_k127_2893731_0 cellulose binding - - - 0.0 1253.0
PYH1_k127_2893731_1 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 536.0
PYH1_k127_2893731_10 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000001968 152.0
PYH1_k127_2893731_11 nitric oxide dioxygenase activity - - - 0.000000000000000000001174 100.0
PYH1_k127_2893731_12 YsiA-like protein, C-terminal region K13770 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000009216 58.0
PYH1_k127_2893731_13 Domain of unknown function (DUF4136) - - - 0.00001009 55.0
PYH1_k127_2893731_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 508.0
PYH1_k127_2893731_3 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 473.0
PYH1_k127_2893731_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 441.0
PYH1_k127_2893731_5 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 440.0
PYH1_k127_2893731_6 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 421.0
PYH1_k127_2893731_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000002324 177.0
PYH1_k127_2893731_8 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000000007099 156.0
PYH1_k127_2893731_9 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000003263 172.0
PYH1_k127_2897517_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 424.0
PYH1_k127_2897517_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 419.0
PYH1_k127_2897517_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
PYH1_k127_2897517_3 PFAM Peptidase family M20 M25 M40 K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 301.0
PYH1_k127_2897517_4 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000001599 168.0
PYH1_k127_2897517_5 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000002805 110.0
PYH1_k127_2897517_6 Binds the 23S rRNA K02909 - - 0.000000000000000000004512 109.0
PYH1_k127_2897517_7 - - - - 0.000000000001793 75.0
PYH1_k127_2903352_0 Tricorn protease C1 domain K08676 - - 8.326e-308 983.0
PYH1_k127_2903352_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000004844 135.0
PYH1_k127_2903352_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000003796 75.0
PYH1_k127_2916011_0 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 388.0
PYH1_k127_2916011_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004658 281.0
PYH1_k127_2916011_2 TIGRFAM YD repeat protein - - - 0.00000000000000000000000000000003629 141.0
PYH1_k127_2916011_3 PFAM PIN domain - - - 0.0000000000000000000000000000004289 130.0
PYH1_k127_2916011_4 PFAM plasmid K06218 - - 0.0000000000000004089 80.0
PYH1_k127_2916011_5 positive regulation of growth - - - 0.00000000000002078 80.0
PYH1_k127_2916011_6 toxin-antitoxin pair type II binding K19159 - - 0.000003122 55.0
PYH1_k127_2949861_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 565.0
PYH1_k127_2949861_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 465.0
PYH1_k127_2949861_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 453.0
PYH1_k127_2949861_3 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 369.0
PYH1_k127_2949861_4 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 349.0
PYH1_k127_2949861_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 317.0
PYH1_k127_2949861_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000003621 178.0
PYH1_k127_2949861_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000005919 153.0
PYH1_k127_2949861_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000003358 97.0
PYH1_k127_2949861_9 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000005812 98.0
PYH1_k127_2966292_0 Domain of Unknown Function (DUF748) - - - 5.586e-201 670.0
PYH1_k127_2966292_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 533.0
PYH1_k127_2966292_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 364.0
PYH1_k127_2966292_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 376.0
PYH1_k127_2966292_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000361 178.0
PYH1_k127_2966292_5 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000005309 111.0
PYH1_k127_2966292_6 Rhomboid family - - - 0.00000000000000001789 91.0
PYH1_k127_2966292_7 Protein of unknown function (DUF1579) - - - 0.00000000004339 70.0
PYH1_k127_2983998_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1037.0
PYH1_k127_2983998_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 499.0
PYH1_k127_2983998_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000886 177.0
PYH1_k127_2983998_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000004911 162.0
PYH1_k127_2983998_12 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000001876 134.0
PYH1_k127_2983998_13 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000002665 128.0
PYH1_k127_2983998_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000002081 121.0
PYH1_k127_2983998_15 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.00000000000000000001264 104.0
PYH1_k127_2983998_16 PFAM PASTA domain K01921,K08884,K12132 - 2.7.11.1,6.3.2.4 0.00000000008125 71.0
PYH1_k127_2983998_17 mttA/Hcf106 family K03116 - - 0.0000000003219 67.0
PYH1_k127_2983998_18 LysM domain - - - 0.00000007537 63.0
PYH1_k127_2983998_19 PFAM helix-turn-helix, Fis-type - - - 0.00001813 56.0
PYH1_k127_2983998_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 387.0
PYH1_k127_2983998_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 303.0
PYH1_k127_2983998_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 282.0
PYH1_k127_2983998_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
PYH1_k127_2983998_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002382 272.0
PYH1_k127_2983998_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000003814 240.0
PYH1_k127_2983998_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000005072 226.0
PYH1_k127_2983998_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000004427 186.0
PYH1_k127_2999898_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.148e-251 809.0
PYH1_k127_2999898_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 4.092e-228 739.0
PYH1_k127_2999898_10 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000000000000000000000001533 113.0
PYH1_k127_2999898_11 Polymer-forming cytoskeletal - - - 0.0000000000004351 76.0
PYH1_k127_2999898_13 - - - - 0.0000007562 61.0
PYH1_k127_2999898_2 Belongs to the aldehyde dehydrogenase family K22187 - - 4.601e-219 698.0
PYH1_k127_2999898_3 Aminotransferase class-V K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 418.0
PYH1_k127_2999898_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 350.0
PYH1_k127_2999898_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 314.0
PYH1_k127_2999898_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000095 267.0
PYH1_k127_2999898_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000002612 245.0
PYH1_k127_2999898_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000003499 213.0
PYH1_k127_2999898_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000002366 139.0
PYH1_k127_3005817_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 7.46e-212 672.0
PYH1_k127_3005817_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 473.0
PYH1_k127_3005817_10 histidine kinase dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000313 176.0
PYH1_k127_3005817_12 - - - - 0.00000000000000000000000000003961 118.0
PYH1_k127_3005817_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000004433 104.0
PYH1_k127_3005817_15 Multicopper K06324 - 1.16.3.3 0.0000000000000001078 91.0
PYH1_k127_3005817_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 410.0
PYH1_k127_3005817_3 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 391.0
PYH1_k127_3005817_4 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003077 300.0
PYH1_k127_3005817_7 - - - - 0.000000000000000000000000000000000000000000000000000000000001289 211.0
PYH1_k127_3005817_8 Sigma-70, region 4 type 2 - - - 0.000000000000000000000000000000000000000000000000001279 192.0
PYH1_k127_3005817_9 - - - - 0.00000000000000000000000000000000000000000000000002451 188.0
PYH1_k127_3011654_0 PFAM Peptidase M16 - - - 0.00000000000000000000000000000000000005671 161.0
PYH1_k127_3011654_1 Insulinase (Peptidase family M16) K07263 - - 0.0002209 47.0
PYH1_k127_3025821_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.497e-302 945.0
PYH1_k127_3025821_1 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000004191 115.0
PYH1_k127_3186270_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 4.586e-316 1005.0
PYH1_k127_3186270_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 575.0
PYH1_k127_3186270_10 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000001812 158.0
PYH1_k127_3186270_11 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000007674 117.0
PYH1_k127_3186270_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 576.0
PYH1_k127_3186270_3 Putative Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 556.0
PYH1_k127_3186270_4 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 539.0
PYH1_k127_3186270_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 369.0
PYH1_k127_3186270_6 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
PYH1_k127_3186270_7 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002602 276.0
PYH1_k127_3186270_8 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000001296 204.0
PYH1_k127_3186270_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000001848 186.0
PYH1_k127_3273170_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 475.0
PYH1_k127_3273170_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 264.0
PYH1_k127_3273170_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000273 156.0
PYH1_k127_3273170_3 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000008617 149.0
PYH1_k127_3273170_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000001055 102.0
PYH1_k127_335371_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 397.0
PYH1_k127_335371_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 307.0
PYH1_k127_335371_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002778 269.0
PYH1_k127_335371_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000003218 228.0
PYH1_k127_335371_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000001607 217.0
PYH1_k127_335371_5 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000005005 190.0
PYH1_k127_335371_6 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000001561 106.0
PYH1_k127_335371_7 Tetratricopeptide repeat - - - 0.00000000000000000000008652 111.0
PYH1_k127_335371_8 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000000002181 101.0
PYH1_k127_335371_9 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000003509 87.0
PYH1_k127_3366701_0 PA domain - - - 0.0 1191.0
PYH1_k127_3366701_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.883e-227 714.0
PYH1_k127_3366701_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 456.0
PYH1_k127_3366701_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000002066 186.0
PYH1_k127_3366701_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000236 138.0
PYH1_k127_3366701_5 PAP2 superfamily - - - 0.000000000000000265 91.0
PYH1_k127_3366701_6 S4 RNA-binding domain K04762 - - 0.000000003703 63.0
PYH1_k127_3368301_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 488.0
PYH1_k127_3368301_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 411.0
PYH1_k127_3368301_2 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005184 288.0
PYH1_k127_3368301_3 Glycosyl transferase family 2 - - - 0.00000000000000000000002639 109.0
PYH1_k127_3368301_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000004954 105.0
PYH1_k127_3429100_0 Heat shock 70 kDa protein K04043 - - 5.498e-290 902.0
PYH1_k127_3429100_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.699e-232 737.0
PYH1_k127_3429100_10 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000007957 195.0
PYH1_k127_3429100_11 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000002885 193.0
PYH1_k127_3429100_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000004389 151.0
PYH1_k127_3429100_13 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000105 149.0
PYH1_k127_3429100_14 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000005574 121.0
PYH1_k127_3429100_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000001172 134.0
PYH1_k127_3429100_16 Domain of unknown function (DUF1844) - - - 0.0000417 51.0
PYH1_k127_3429100_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 599.0
PYH1_k127_3429100_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 527.0
PYH1_k127_3429100_4 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 409.0
PYH1_k127_3429100_5 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002125 272.0
PYH1_k127_3429100_6 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
PYH1_k127_3429100_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000001759 243.0
PYH1_k127_3429100_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000004249 195.0
PYH1_k127_3429100_9 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000002049 184.0
PYH1_k127_3438495_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 2.584e-247 801.0
PYH1_k127_3438495_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 555.0
PYH1_k127_3438495_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 495.0
PYH1_k127_3438495_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 357.0
PYH1_k127_3438495_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 301.0
PYH1_k127_3438495_5 Acyl-transferase - - - 0.000000000000000000000000000000000000000000000000003754 197.0
PYH1_k127_3438495_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000004122 181.0
PYH1_k127_3438495_7 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000002562 144.0
PYH1_k127_3438495_8 - - - - 0.0000000000000000000008584 102.0
PYH1_k127_3448463_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 302.0
PYH1_k127_3448463_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000004014 146.0
PYH1_k127_3448463_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000001313 125.0
PYH1_k127_3453285_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 522.0
PYH1_k127_3453285_1 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006662 248.0
PYH1_k127_3453285_2 AI-2E family transporter - - - 0.0000000000000000000000000000003053 138.0
PYH1_k127_3453285_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000003716 129.0
PYH1_k127_3453285_4 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000003649 82.0
PYH1_k127_3453285_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000003708 95.0
PYH1_k127_3453285_6 chlorophyll binding - - - 0.00001107 58.0
PYH1_k127_3458271_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008474 278.0
PYH1_k127_3458271_1 HEPN domain - - - 0.000000000000000000000000000000000001762 145.0
PYH1_k127_3458271_2 Domain of unknown function (DUF3943) - - - 0.000000000000000004259 96.0
PYH1_k127_3458271_3 Domain of unknown function (DUF3943) - - - 0.0000000000001637 74.0
PYH1_k127_3458271_4 - K01992,K19341 - - 0.0000000000002729 74.0
PYH1_k127_3458271_5 Nucleotidyltransferase domain - - - 0.000000000000382 77.0
PYH1_k127_3458271_6 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000005031 76.0
PYH1_k127_3458271_7 Putative regulatory protein - - - 0.000005039 57.0
PYH1_k127_3474731_0 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 317.0
PYH1_k127_3474731_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000112 287.0
PYH1_k127_3474731_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000008609 220.0
PYH1_k127_3474731_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000007165 105.0
PYH1_k127_3474731_4 ATP synthase alpha/beta chain, C terminal domain - - - 0.0000000000000000000008291 102.0
PYH1_k127_3474731_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000652 88.0
PYH1_k127_3474731_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000007346 89.0
PYH1_k127_3474731_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000008066 51.0
PYH1_k127_3474731_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0001756 51.0
PYH1_k127_348463_0 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 417.0
PYH1_k127_348463_1 Translation elongation factor P EF-P - - - 0.00000000000000000000000000000000000000000000000001397 184.0
PYH1_k127_348463_2 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000008264 177.0
PYH1_k127_348463_3 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000005653 137.0
PYH1_k127_3494278_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 8.894e-239 769.0
PYH1_k127_3494278_1 Heat shock 70 kDa protein K04043 - - 8.297e-216 685.0
PYH1_k127_3494278_10 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000002409 175.0
PYH1_k127_3494278_11 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000004246 151.0
PYH1_k127_3494278_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000001292 133.0
PYH1_k127_3494278_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000006415 109.0
PYH1_k127_3494278_14 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000003411 88.0
PYH1_k127_3494278_15 RecX family K03565 - - 0.00000000005773 70.0
PYH1_k127_3494278_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 1.618e-194 635.0
PYH1_k127_3494278_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 521.0
PYH1_k127_3494278_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 413.0
PYH1_k127_3494278_5 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 371.0
PYH1_k127_3494278_6 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
PYH1_k127_3494278_7 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001554 271.0
PYH1_k127_3494278_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
PYH1_k127_3494278_9 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000002528 181.0
PYH1_k127_3538754_0 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 435.0
PYH1_k127_3538754_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 322.0
PYH1_k127_3538754_2 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 304.0
PYH1_k127_3538754_3 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000002688 182.0
PYH1_k127_3538754_4 - - - - 0.000000000000000000000000000000000000000113 156.0
PYH1_k127_3538754_5 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000693 132.0
PYH1_k127_3538754_6 - - - - 0.0000000000000000000002645 110.0
PYH1_k127_3548333_0 PFAM Type II secretion system protein E K02652 - - 1.126e-214 678.0
PYH1_k127_3548333_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007568 285.0
PYH1_k127_3548333_2 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000758 215.0
PYH1_k127_3548333_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000003041 100.0
PYH1_k127_3548333_4 Type II and III secretion system protein K02453 - - 0.00001189 55.0
PYH1_k127_3548333_5 PFAM Fimbrial assembly family protein K02663 - - 0.0005903 52.0
PYH1_k127_3548387_0 NAD synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 556.0
PYH1_k127_3548387_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 528.0
PYH1_k127_3548387_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 265.0
PYH1_k127_3548387_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001887 216.0
PYH1_k127_3548387_4 Psort location Cytoplasmic, score 8.96 K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000003951 170.0
PYH1_k127_3548387_5 PIN domain - - - 0.000000000000000000000000000000001597 134.0
PYH1_k127_3548387_6 Glycosyl transferase family 2 - - - 0.00000000000000000000000000003445 136.0
PYH1_k127_3548387_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000009717 77.0
PYH1_k127_3548387_8 RDD family - - - 0.00003094 54.0
PYH1_k127_355099_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1304.0
PYH1_k127_355099_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000008536 119.0
PYH1_k127_355099_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000009562 108.0
PYH1_k127_355099_3 tryptophanase activity K01667 - 4.1.99.1 0.000000001065 66.0
PYH1_k127_355350_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 351.0
PYH1_k127_355350_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 320.0
PYH1_k127_355350_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000006897 165.0
PYH1_k127_355350_3 Ribosomal L32p protein family K02911 - - 0.00000000000000000004646 91.0
PYH1_k127_355350_4 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000001213 91.0
PYH1_k127_355350_5 Glycosyl transferase 4-like domain - - - 0.00000003963 62.0
PYH1_k127_3569525_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 529.0
PYH1_k127_3569525_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 391.0
PYH1_k127_3569525_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 340.0
PYH1_k127_3569525_3 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000009781 175.0
PYH1_k127_3569525_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000001119 134.0
PYH1_k127_3569525_5 PIN domain - - - 0.00000001765 61.0
PYH1_k127_3600170_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 2.317e-256 812.0
PYH1_k127_3600170_1 TonB-dependent Receptor Plug Domain K02014 - - 5.903e-200 646.0
PYH1_k127_3600170_2 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000003038 198.0
PYH1_k127_3627800_0 PFAM Protein synthesis factor, GTP-binding K06207 - - 1.096e-224 709.0
PYH1_k127_3627800_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000005701 143.0
PYH1_k127_3627800_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000003718 104.0
PYH1_k127_3627800_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000007598 78.0
PYH1_k127_3640627_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1020.0
PYH1_k127_3640627_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000001221 176.0
PYH1_k127_3640627_2 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.000000000000004616 76.0
PYH1_k127_3647644_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 316.0
PYH1_k127_3647644_1 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.0000000000000000000004176 106.0
PYH1_k127_3647644_2 Glycosyl transferases group 1 - - - 0.0000000000001304 85.0
PYH1_k127_3647644_3 transferase activity, transferring acyl groups - - - 0.000000000426 71.0
PYH1_k127_3647644_4 PKD domain - - - 0.0000000159 68.0
PYH1_k127_3715832_0 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 350.0
PYH1_k127_3715832_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006866 290.0
PYH1_k127_3715832_2 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000001219 248.0
PYH1_k127_3715832_3 Surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000002742 250.0
PYH1_k127_3715832_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000002372 205.0
PYH1_k127_3715832_5 HPP family - - - 0.000000000000000000000000000000000000000000000000000002833 209.0
PYH1_k127_3715832_6 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000656 185.0
PYH1_k127_3715832_7 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000001098 70.0
PYH1_k127_3715835_0 Periplasmic copper-binding protein (NosD) K07218 - - 3.22e-198 638.0
PYH1_k127_3715835_1 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 376.0
PYH1_k127_3715835_2 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 332.0
PYH1_k127_3715835_3 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003273 256.0
PYH1_k127_3715835_4 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000005188 179.0
PYH1_k127_3719971_0 4Fe-4S dicluster domain - - - 1.319e-276 857.0
PYH1_k127_3719971_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 568.0
PYH1_k127_3719971_10 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000004625 173.0
PYH1_k127_3719971_11 - - - - 0.00000000000000000000000000000001484 131.0
PYH1_k127_3719971_12 TfoX N-terminal domain - - - 0.00000000000000000000001525 102.0
PYH1_k127_3719971_13 PFAM Nitrate reductase gamma subunit - - - 0.00000001472 55.0
PYH1_k127_3719971_14 Protein of unknown function (DUF1697) - - - 0.000229 51.0
PYH1_k127_3719971_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 527.0
PYH1_k127_3719971_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 411.0
PYH1_k127_3719971_4 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 318.0
PYH1_k127_3719971_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 321.0
PYH1_k127_3719971_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004699 305.0
PYH1_k127_3719971_7 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000913 279.0
PYH1_k127_3719971_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000003943 191.0
PYH1_k127_3719971_9 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000000000000000000000005448 171.0
PYH1_k127_374351_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000001676 153.0
PYH1_k127_374351_1 glycosyl transferase - - - 0.0000000000000000000006401 101.0
PYH1_k127_374351_2 manganese ion transmembrane transporter activity - - - 0.000000000000000002153 94.0
PYH1_k127_374351_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000001718 91.0
PYH1_k127_3752692_0 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000002486 216.0
PYH1_k127_3752692_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000001389 121.0
PYH1_k127_3752692_2 Male sterility protein - - - 0.00000000000004473 86.0
PYH1_k127_3752692_3 amine dehydrogenase activity - - - 0.0000001286 64.0
PYH1_k127_3752692_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001791 64.0
PYH1_k127_3752692_5 - - - - 0.00002211 54.0
PYH1_k127_3819526_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 6.03e-317 986.0
PYH1_k127_3819526_1 TIGRFAM type VI secretion system Vgr family protein K11904 - - 3.4e-205 668.0
PYH1_k127_3819526_11 serine threonine protein kinase K12132 - 2.7.11.1 0.0004452 53.0
PYH1_k127_3819526_2 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 370.0
PYH1_k127_3819526_3 type VI secretion protein K11900,K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 348.0
PYH1_k127_3819526_4 metal cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000005215 219.0
PYH1_k127_3819526_5 - - - - 0.00000000000000000000000000000000000000000000000000000002399 206.0
PYH1_k127_3819526_6 - - - - 0.000000000000000000000000000000000000000003699 169.0
PYH1_k127_3819526_7 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000005318 143.0
PYH1_k127_3819526_8 PAAR motif - - - 0.00000000000000000008927 97.0
PYH1_k127_3819526_9 Forkhead associated domain - - - 0.00000000000000003033 92.0
PYH1_k127_3896573_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000141 284.0
PYH1_k127_3896573_1 - - - - 0.0000000000000000000000000000000000000000000000000000002081 211.0
PYH1_k127_3896573_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000002448 134.0
PYH1_k127_3925702_0 phosphoribosylamine-glycine ligase activity K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 445.0
PYH1_k127_3925702_1 Bacterial transcriptional activator domain - - - 0.0002895 52.0
PYH1_k127_3927293_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
PYH1_k127_3927293_1 SCO1/SenC K07152 - - 0.00000000000000000000000000000000003043 145.0
PYH1_k127_3927293_2 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000001403 137.0
PYH1_k127_3927293_3 Hpt domain - - - 0.0000000000000000000000007926 119.0
PYH1_k127_3927293_4 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000754 101.0
PYH1_k127_3936178_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 595.0
PYH1_k127_3936178_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000016 262.0
PYH1_k127_3936178_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000004018 131.0
PYH1_k127_3936178_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000131 127.0
PYH1_k127_3936178_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000004205 111.0
PYH1_k127_3936178_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000004283 96.0
PYH1_k127_3936178_14 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000005419 66.0
PYH1_k127_3936178_15 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000002101 68.0
PYH1_k127_3936178_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000003784 270.0
PYH1_k127_3936178_3 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003469 206.0
PYH1_k127_3936178_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000005572 196.0
PYH1_k127_3936178_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000004447 193.0
PYH1_k127_3936178_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000005171 183.0
PYH1_k127_3936178_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000005587 171.0
PYH1_k127_3936178_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000004314 167.0
PYH1_k127_3936178_9 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000004612 156.0
PYH1_k127_3957404_0 Cytochrome bd terminal oxidase subunit I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 319.0
PYH1_k127_3957404_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000762 257.0
PYH1_k127_3957404_2 ribonuclease - - - 0.000000000000000000000000000000001165 135.0
PYH1_k127_3957404_3 Barstar (barnase inhibitor) - - - 0.0000000000000000009187 96.0
PYH1_k127_3957404_4 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000001657 79.0
PYH1_k127_3957404_5 membrane protein (DUF2238) K08984 - - 0.0000000001217 63.0
PYH1_k127_3957404_6 Antitoxin component of a toxin-antitoxin (TA) module - GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 - 0.000001297 55.0
PYH1_k127_3999679_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000542 134.0
PYH1_k127_3999679_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000006059 139.0
PYH1_k127_3999679_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000002298 107.0
PYH1_k127_3999679_3 Bacterial membrane protein, YfhO - - - 0.0000044 55.0
PYH1_k127_4033389_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1072.0
PYH1_k127_4033389_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.702e-252 807.0
PYH1_k127_4033389_10 PFAM Stage II sporulation - - - 0.00000000000000000000000000000000000002758 159.0
PYH1_k127_4033389_11 - - - - 0.000000000000000000000000003081 129.0
PYH1_k127_4033389_12 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000006072 104.0
PYH1_k127_4033389_13 - - - - 0.000001143 58.0
PYH1_k127_4033389_14 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000035 58.0
PYH1_k127_4033389_2 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 6.009e-222 707.0
PYH1_k127_4033389_3 Polysulphide reductase, NrfD K00185 - - 1.342e-201 640.0
PYH1_k127_4033389_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 357.0
PYH1_k127_4033389_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 340.0
PYH1_k127_4033389_6 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 287.0
PYH1_k127_4033389_7 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
PYH1_k127_4033389_8 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000009796 212.0
PYH1_k127_4033389_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000001396 196.0
PYH1_k127_4058827_0 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 534.0
PYH1_k127_4058827_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 406.0
PYH1_k127_4058827_2 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002063 280.0
PYH1_k127_4058827_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000004262 164.0
PYH1_k127_4058827_4 PFAM FecR protein - - - 0.0000000001504 74.0
PYH1_k127_4058827_5 Involved in formation and maintenance of cell shape K03570 - - 0.0004847 50.0
PYH1_k127_40627_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 588.0
PYH1_k127_40627_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000001213 250.0
PYH1_k127_40627_2 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.000000000000000005018 89.0
PYH1_k127_4079947_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 319.0
PYH1_k127_4079947_1 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000004145 244.0
PYH1_k127_4079947_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000006881 78.0
PYH1_k127_4079947_4 Yip1 domain - - - 0.000000000001629 78.0
PYH1_k127_4079947_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000001279 63.0
PYH1_k127_4079947_6 ABC transporter K02003 - - 0.000000007065 63.0
PYH1_k127_4083643_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 325.0
PYH1_k127_4083643_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000006087 260.0
PYH1_k127_4083643_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001415 263.0
PYH1_k127_4083643_3 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000004573 222.0
PYH1_k127_4083643_4 Cytidylate kinase-like family K00945 - 2.7.4.25 0.0000000000000000006012 96.0
PYH1_k127_4134736_0 Large extracellular alpha-helical protein - - - 0.0 2173.0
PYH1_k127_4134736_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 411.0
PYH1_k127_4134736_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 356.0
PYH1_k127_4134736_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 345.0
PYH1_k127_4134736_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 306.0
PYH1_k127_4134736_5 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 292.0
PYH1_k127_4134736_6 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000911 238.0
PYH1_k127_4140156_0 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 551.0
PYH1_k127_4140156_1 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 499.0
PYH1_k127_4140156_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 466.0
PYH1_k127_4140156_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 414.0
PYH1_k127_4140156_4 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 400.0
PYH1_k127_4140156_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000001113 246.0
PYH1_k127_4140156_6 Domain of unknown function (DUF4412) - - - 0.0000000000000000000000000000000000000264 155.0
PYH1_k127_4140156_7 Domain of unknown function (DUF4412) - - - 0.00000000000000000000000000000001165 139.0
PYH1_k127_4140156_8 P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000002737 105.0
PYH1_k127_4162708_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 521.0
PYH1_k127_4162708_1 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 386.0
PYH1_k127_4162708_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 307.0
PYH1_k127_4162708_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000006704 175.0
PYH1_k127_4162708_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000004243 94.0
PYH1_k127_4246497_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 581.0
PYH1_k127_4246497_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000248 225.0
PYH1_k127_4246497_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001175 137.0
PYH1_k127_4246497_3 Plasmid stability protein - - - 0.000001024 53.0
PYH1_k127_4261521_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.73e-202 640.0
PYH1_k127_4261521_1 B12 binding domain - - - 9.321e-201 644.0
PYH1_k127_4261521_2 associated with various cellular activities K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 488.0
PYH1_k127_4261521_3 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006115 302.0
PYH1_k127_4261521_4 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003523 259.0
PYH1_k127_4261521_5 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000117 153.0
PYH1_k127_4261521_6 SMART Tetratricopeptide - - - 0.00000000000009646 85.0
PYH1_k127_4261521_8 VanZ like family - - - 0.0009063 52.0
PYH1_k127_4262877_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002372 311.0
PYH1_k127_4262877_1 Cyclic nucleotide-monophosphate binding domain K03316 - - 0.0000000844 64.0
PYH1_k127_4262877_2 Transmembrane secretion effector - - - 0.0000057 59.0
PYH1_k127_4304716_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1311.0
PYH1_k127_4304716_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.777e-199 639.0
PYH1_k127_4304716_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 463.0
PYH1_k127_4304716_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 462.0
PYH1_k127_4304716_4 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 350.0
PYH1_k127_4304716_5 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000007308 256.0
PYH1_k127_4304716_6 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000101 231.0
PYH1_k127_4304716_7 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000001126 109.0
PYH1_k127_4304716_8 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000001931 72.0
PYH1_k127_4304716_9 protein involved in formation of periplasmic nitrate reductase K02570 - - 0.0000002221 64.0
PYH1_k127_4316083_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 466.0
PYH1_k127_4316083_1 Pro-kumamolisin, activation domain K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 420.0
PYH1_k127_4316083_10 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000008754 74.0
PYH1_k127_4316083_11 PFAM DNA polymerase beta domain protein region K07075 - - 0.000000000008715 79.0
PYH1_k127_4316083_12 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000001158 55.0
PYH1_k127_4316083_13 heat shock protein binding K05516,K05801 - - 0.00001043 58.0
PYH1_k127_4316083_2 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000001175 200.0
PYH1_k127_4316083_3 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000000002758 153.0
PYH1_k127_4316083_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000005187 148.0
PYH1_k127_4316083_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000002553 139.0
PYH1_k127_4316083_6 Protein of unknown function DUF86 - - - 0.0000000000000000000000002071 113.0
PYH1_k127_4316083_7 Domain of unknown function (DUF4126) - - - 0.0000000000000000004531 102.0
PYH1_k127_4316083_8 PQQ enzyme repeat - - - 0.000000000000002581 91.0
PYH1_k127_4316083_9 - - - - 0.000000000000009257 81.0
PYH1_k127_4321710_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1200.0
PYH1_k127_4321710_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 1.043e-255 798.0
PYH1_k127_4321710_10 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 340.0
PYH1_k127_4321710_11 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000002642 194.0
PYH1_k127_4321710_12 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.000000000000000000000000000000004631 142.0
PYH1_k127_4321710_13 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000002609 136.0
PYH1_k127_4321710_14 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000000000000000001871 144.0
PYH1_k127_4321710_15 - - - - 0.000000000000000008027 98.0
PYH1_k127_4321710_2 lysine biosynthetic process via aminoadipic acid - - - 5.557e-212 679.0
PYH1_k127_4321710_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 564.0
PYH1_k127_4321710_4 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 484.0
PYH1_k127_4321710_5 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 406.0
PYH1_k127_4321710_6 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 411.0
PYH1_k127_4321710_7 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 366.0
PYH1_k127_4321710_8 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 352.0
PYH1_k127_4321710_9 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 319.0
PYH1_k127_4326802_0 Dehydrogenase E1 component K11381 - 1.2.4.4 5.539e-302 940.0
PYH1_k127_4326802_1 arylsulfatase A K01130 - 3.1.6.1 3.992e-265 822.0
PYH1_k127_4326802_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000001065 72.0
PYH1_k127_4326802_11 - - - - 0.0000003535 63.0
PYH1_k127_4326802_12 - - - - 0.00006322 51.0
PYH1_k127_4326802_13 bacterial OsmY and nodulation domain - - - 0.0004983 49.0
PYH1_k127_4326802_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 7.688e-205 662.0
PYH1_k127_4326802_3 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 404.0
PYH1_k127_4326802_4 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 358.0
PYH1_k127_4326802_5 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002355 295.0
PYH1_k127_4326802_6 receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000002109 222.0
PYH1_k127_4326802_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000002344 121.0
PYH1_k127_4326802_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000002234 83.0
PYH1_k127_4326802_9 Parallel beta-helix repeats - - - 0.000000000106 76.0
PYH1_k127_4347635_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 454.0
PYH1_k127_4347635_1 PFAM filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 406.0
PYH1_k127_4347635_10 response regulator, receiver - - - 0.00000000000000000000000000000001423 134.0
PYH1_k127_4347635_11 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000000004643 124.0
PYH1_k127_4347635_12 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.00000000000000000000000000001255 126.0
PYH1_k127_4347635_13 Protein of unknown function DUF86 - - - 0.00000000000000000000000000002343 121.0
PYH1_k127_4347635_14 HIRAN - - - 0.000000000000000000000000002746 115.0
PYH1_k127_4347635_15 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000001459 119.0
PYH1_k127_4347635_16 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000002456 101.0
PYH1_k127_4347635_17 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000004226 100.0
PYH1_k127_4347635_18 PIN domain - - - 0.000000000000000000002179 95.0
PYH1_k127_4347635_19 mRNA binding K07339 - - 0.00000000000000000003749 98.0
PYH1_k127_4347635_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
PYH1_k127_4347635_20 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000000005875 91.0
PYH1_k127_4347635_21 heat shock protein binding K05516 - - 0.00000000000000003617 93.0
PYH1_k127_4347635_22 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 - 2.7.7.13,2.7.7.99 0.00000000000002588 80.0
PYH1_k127_4347635_23 - - - - 0.0000000000162 69.0
PYH1_k127_4347635_24 - - - - 0.000000001065 66.0
PYH1_k127_4347635_25 WYL domain K13572 - - 0.000000001931 60.0
PYH1_k127_4347635_26 - - - - 0.00003713 54.0
PYH1_k127_4347635_27 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0002174 54.0
PYH1_k127_4347635_28 Type II transport protein GspH K08084 - - 0.0007529 49.0
PYH1_k127_4347635_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000001053 279.0
PYH1_k127_4347635_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000476 261.0
PYH1_k127_4347635_5 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000005058 231.0
PYH1_k127_4347635_6 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000001782 209.0
PYH1_k127_4347635_7 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000003239 151.0
PYH1_k127_4347635_8 Flavoprotein K03186 - 2.5.1.129 0.00000000000000000000000000000000001874 144.0
PYH1_k127_4347635_9 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000004241 131.0
PYH1_k127_4356755_0 permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 475.0
PYH1_k127_4356755_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 344.0
PYH1_k127_4356755_2 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000004815 254.0
PYH1_k127_4356755_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000004206 201.0
PYH1_k127_4356755_4 Transcriptional regulator K03892,K21903 - - 0.0000000000000000002128 93.0
PYH1_k127_4356755_5 redox-active disulfide protein 2 - - - 0.0000000000000006564 83.0
PYH1_k127_4377000_0 4Fe-4S dicluster domain - - - 8.433e-205 651.0
PYH1_k127_4377000_1 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 549.0
PYH1_k127_4377000_11 HEAT-like repeat - - - 0.0000004341 64.0
PYH1_k127_4377000_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 554.0
PYH1_k127_4377000_3 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 496.0
PYH1_k127_4377000_4 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 444.0
PYH1_k127_4377000_5 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 383.0
PYH1_k127_4377000_6 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000002637 171.0
PYH1_k127_4377000_7 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000001599 108.0
PYH1_k127_4377000_8 Nitrate reductase gamma subunit - - - 0.000000000000000000004145 95.0
PYH1_k127_4377000_9 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000001646 78.0
PYH1_k127_4379104_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 512.0
PYH1_k127_4379104_1 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 309.0
PYH1_k127_4379104_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000265 206.0
PYH1_k127_4379104_3 KR domain - - - 0.00000000000000000000001076 110.0
PYH1_k127_4393934_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 494.0
PYH1_k127_4393934_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 430.0
PYH1_k127_4393934_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 396.0
PYH1_k127_4393934_3 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 291.0
PYH1_k127_4393934_4 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004423 260.0
PYH1_k127_4393934_5 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000001292 230.0
PYH1_k127_4393934_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000002087 162.0
PYH1_k127_4393934_7 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000001496 74.0
PYH1_k127_4393934_8 PIN domain - - - 0.00000005258 60.0
PYH1_k127_4456754_0 Peptidase m28 - - - 1.577e-212 676.0
PYH1_k127_4456754_1 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 512.0
PYH1_k127_4456754_10 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000007173 217.0
PYH1_k127_4456754_11 PFAM CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000005804 198.0
PYH1_k127_4456754_12 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000002136 166.0
PYH1_k127_4456754_13 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000005111 142.0
PYH1_k127_4456754_14 diguanylate cyclase - - - 0.00000000000000000000000000000000006054 146.0
PYH1_k127_4456754_15 Phosphate-selective porin O and P - - - 0.0000000000000000000000000001559 130.0
PYH1_k127_4456754_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 488.0
PYH1_k127_4456754_3 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 420.0
PYH1_k127_4456754_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 400.0
PYH1_k127_4456754_5 PFAM Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 319.0
PYH1_k127_4456754_6 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001112 266.0
PYH1_k127_4456754_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 273.0
PYH1_k127_4456754_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000002658 235.0
PYH1_k127_4456754_9 transport system permease K01998 - - 0.0000000000000000000000000000000000000000000000000000000000237 229.0
PYH1_k127_4473490_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 381.0
PYH1_k127_4473490_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000003261 220.0
PYH1_k127_4473490_2 GYD domain - - - 0.0000000000000000000001896 100.0
PYH1_k127_4473490_3 nucleotidyltransferase activity - - - 0.000000006864 63.0
PYH1_k127_4473490_4 Protein of unknown function DUF86 - - - 0.0000005852 60.0
PYH1_k127_4473490_5 - - - - 0.0001453 51.0
PYH1_k127_4488451_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 379.0
PYH1_k127_4488451_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 344.0
PYH1_k127_4488451_2 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000009116 178.0
PYH1_k127_4488451_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000001628 159.0
PYH1_k127_4488451_4 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000000000000000001519 151.0
PYH1_k127_4488451_5 AMMECR1 K09141 - - 0.00000000000000000000000000000000008362 152.0
PYH1_k127_4488451_6 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000001324 140.0
PYH1_k127_4488451_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000004024 64.0
PYH1_k127_450476_0 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006095 261.0
PYH1_k127_450476_1 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000039 210.0
PYH1_k127_450476_10 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00004342 47.0
PYH1_k127_450476_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000003563 210.0
PYH1_k127_450476_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000007797 174.0
PYH1_k127_450476_4 - - - - 0.0000000000000000000000000000000000000001985 155.0
PYH1_k127_450476_5 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000002636 157.0
PYH1_k127_450476_6 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000005248 113.0
PYH1_k127_450476_7 - - - - 0.000000000000002702 79.0
PYH1_k127_450476_8 formate dehydrogenase K00127 - - 0.000000000000003212 89.0
PYH1_k127_450476_9 Papain-like cysteine protease AvrRpt2 - - - 0.000001029 57.0
PYH1_k127_4510636_0 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 458.0
PYH1_k127_4510636_1 CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
PYH1_k127_4510636_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000004745 62.0
PYH1_k127_4510636_3 Domain of unknown function (DUF4388) - - - 0.000006319 59.0
PYH1_k127_4542937_0 K+ potassium transporter K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 346.0
PYH1_k127_4542937_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00008879 48.0
PYH1_k127_4561653_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1060.0
PYH1_k127_4561653_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 538.0
PYH1_k127_4561653_10 - - - - 0.00000005086 61.0
PYH1_k127_4561653_11 TIGRFAM regulatory protein, FmdB - - - 0.00000005421 60.0
PYH1_k127_4561653_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 359.0
PYH1_k127_4561653_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 349.0
PYH1_k127_4561653_4 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 312.0
PYH1_k127_4561653_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000002807 171.0
PYH1_k127_4561653_6 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000004125 166.0
PYH1_k127_4561653_7 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000002097 106.0
PYH1_k127_4561653_8 Protein of unknown function (DUF2892) - - - 0.0000000000000000002115 96.0
PYH1_k127_4561653_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000003127 96.0
PYH1_k127_4590825_0 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000001016 204.0
PYH1_k127_4590825_1 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000001526 163.0
PYH1_k127_4590825_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000004135 103.0
PYH1_k127_4590825_3 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000002094 91.0
PYH1_k127_4590825_4 Protein of unknown function (DUF465) - - - 0.0005921 45.0
PYH1_k127_4597891_0 MacB-like periplasmic core domain K02004 - - 9.777e-320 1003.0
PYH1_k127_4597891_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 534.0
PYH1_k127_4597891_10 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000478 130.0
PYH1_k127_4597891_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000003835 102.0
PYH1_k127_4597891_12 Carboxymuconolactone decarboxylase family - - - 0.0000004287 56.0
PYH1_k127_4597891_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K21137 - - 0.0002999 44.0
PYH1_k127_4597891_15 FtsX-like permease family - - - 0.0008814 51.0
PYH1_k127_4597891_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 465.0
PYH1_k127_4597891_3 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 390.0
PYH1_k127_4597891_4 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 353.0
PYH1_k127_4597891_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 321.0
PYH1_k127_4597891_6 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003564 283.0
PYH1_k127_4597891_7 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 256.0
PYH1_k127_4597891_8 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000791 244.0
PYH1_k127_4597891_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000003929 215.0
PYH1_k127_4610951_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 443.0
PYH1_k127_4610951_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
PYH1_k127_4610951_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000001798 189.0
PYH1_k127_4610951_3 - - - - 0.000000000001905 79.0
PYH1_k127_4610951_4 Redoxin K02199 - - 0.000376 50.0
PYH1_k127_4647543_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.133e-214 686.0
PYH1_k127_4647543_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000002733 227.0
PYH1_k127_4647543_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000005019 104.0
PYH1_k127_4647543_3 Protein of unknown function (DUF503) K09764 - - 0.00000000008684 67.0
PYH1_k127_4664515_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.071e-209 671.0
PYH1_k127_4664515_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000006949 180.0
PYH1_k127_4664515_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001507 144.0
PYH1_k127_4664515_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000009004 81.0
PYH1_k127_4683846_0 topoisomerase K02469 - 5.99.1.3 3.541e-267 844.0
PYH1_k127_4683846_1 - - - - 0.0000000000000000000000000000000000000000000897 176.0
PYH1_k127_4683846_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000003346 179.0
PYH1_k127_4695878_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 414.0
PYH1_k127_4695878_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 354.0
PYH1_k127_4695878_2 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000002138 109.0
PYH1_k127_4695878_3 Efflux transporter, RND family, MFP subunit K02005 - - 0.000000000002297 71.0
PYH1_k127_4713892_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 559.0
PYH1_k127_4713892_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 407.0
PYH1_k127_4713892_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 389.0
PYH1_k127_4713892_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000001323 164.0
PYH1_k127_4713892_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000001673 91.0
PYH1_k127_4713892_5 PFAM PEGA domain - - - 0.0000179 55.0
PYH1_k127_4716220_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 488.0
PYH1_k127_4716220_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
PYH1_k127_4716220_2 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 359.0
PYH1_k127_4716220_3 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000000000000000000001052 209.0
PYH1_k127_4716220_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000001323 194.0
PYH1_k127_4716220_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000002889 164.0
PYH1_k127_4716220_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.00000000000000000000000001242 113.0
PYH1_k127_4716220_7 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000003806 91.0
PYH1_k127_4716220_8 4Fe-4S dicluster domain K08358 - - 0.0000000004744 66.0
PYH1_k127_4716220_9 Nitrate reductase delta subunit - - - 0.0000003846 60.0
PYH1_k127_4724629_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 524.0
PYH1_k127_4724629_1 Heavy metal transport detoxification protein K01533,K17686,K19597 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 365.0
PYH1_k127_4724629_2 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000024 138.0
PYH1_k127_4728258_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 8.225e-225 727.0
PYH1_k127_4728258_1 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000001076 186.0
PYH1_k127_4728258_2 Diguanylate cyclase - - - 0.0000002692 53.0
PYH1_k127_4728258_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000008651 62.0
PYH1_k127_4761341_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1331.0
PYH1_k127_4761341_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 4.733e-276 867.0
PYH1_k127_4761341_2 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000004583 140.0
PYH1_k127_4761341_3 PFAM O-Antigen - - - 0.000006428 60.0
PYH1_k127_4765056_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 445.0
PYH1_k127_4765056_1 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 412.0
PYH1_k127_4765056_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000003367 87.0
PYH1_k127_4765056_2 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 380.0
PYH1_k127_4765056_3 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 376.0
PYH1_k127_4765056_4 Proline racemase K01777,K12658 - 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 339.0
PYH1_k127_4765056_5 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 290.0
PYH1_k127_4765056_6 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001032 262.0
PYH1_k127_4765056_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000006482 197.0
PYH1_k127_4765056_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000001147 114.0
PYH1_k127_4765056_9 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000001119 97.0
PYH1_k127_4769856_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 583.0
PYH1_k127_4769856_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 386.0
PYH1_k127_4769856_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004325 280.0
PYH1_k127_4769856_3 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000002841 230.0
PYH1_k127_4769856_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000001139 194.0
PYH1_k127_4769856_6 Belongs to the UPF0235 family K09131 - - 0.0001244 55.0
PYH1_k127_4822654_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 405.0
PYH1_k127_4822654_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003607 270.0
PYH1_k127_4822654_2 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000001402 248.0
PYH1_k127_4822654_3 pfam abc K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000002794 239.0
PYH1_k127_4822654_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002719 240.0
PYH1_k127_4822654_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000002924 173.0
PYH1_k127_4822654_6 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000009054 174.0
PYH1_k127_4822654_7 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000216 145.0
PYH1_k127_4882052_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 518.0
PYH1_k127_4882052_1 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 380.0
PYH1_k127_4882052_2 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000001549 259.0
PYH1_k127_4882052_3 response regulator, receiver - - - 0.000000000000000000000000001291 130.0
PYH1_k127_4882052_4 Protein of unknown function (DUF2283) - - - 0.000000000000002376 79.0
PYH1_k127_4915096_0 LmbE family - - - 1.34e-229 737.0
PYH1_k127_4915096_1 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 383.0
PYH1_k127_4915096_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002294 235.0
PYH1_k127_4915096_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002475 232.0
PYH1_k127_4915096_4 CAAX protease self-immunity K07052 - - 0.00000000009221 72.0
PYH1_k127_4919536_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 512.0
PYH1_k127_4919536_1 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 428.0
PYH1_k127_4919536_10 Alpha beta hydrolase - - - 0.0000000000000000000000000000006396 135.0
PYH1_k127_4919536_11 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000013 101.0
PYH1_k127_4919536_12 - - - - 0.00008226 45.0
PYH1_k127_4919536_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0002875 51.0
PYH1_k127_4919536_2 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 383.0
PYH1_k127_4919536_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 336.0
PYH1_k127_4919536_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 334.0
PYH1_k127_4919536_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000006849 273.0
PYH1_k127_4919536_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000005291 197.0
PYH1_k127_4919536_7 gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000003937 194.0
PYH1_k127_4919536_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000004696 176.0
PYH1_k127_4919536_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002967 139.0
PYH1_k127_4962877_0 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 346.0
PYH1_k127_4962877_1 twitching motility protein PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 347.0
PYH1_k127_4962877_2 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000007945 183.0
PYH1_k127_4962877_3 Histidine kinase - - - 0.00000000000000000000000001619 128.0
PYH1_k127_4962877_4 Bacterial membrane protein YfhO - - - 0.0000000000001272 83.0
PYH1_k127_500581_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.228e-238 747.0
PYH1_k127_500581_1 O-acetylhomoserine K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 494.0
PYH1_k127_500581_10 regulation of translation K03530 - - 0.0000000000000000000000000000000006595 137.0
PYH1_k127_500581_11 - K07039 - - 0.000000000001785 70.0
PYH1_k127_500581_12 Bacterial antitoxin of type II TA system, VapB - - - 0.0001312 47.0
PYH1_k127_500581_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0002803 51.0
PYH1_k127_500581_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 427.0
PYH1_k127_500581_3 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000009396 261.0
PYH1_k127_500581_4 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000001106 215.0
PYH1_k127_500581_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000001055 216.0
PYH1_k127_500581_6 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000007049 203.0
PYH1_k127_500581_7 - K07039 - - 0.00000000000000000000000000000000000000000000005572 184.0
PYH1_k127_500581_8 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000005043 165.0
PYH1_k127_500581_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000004345 141.0
PYH1_k127_5035933_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002556 261.0
PYH1_k127_5035933_1 Bacterial membrane protein, YfhO - - - 0.000000000000002514 91.0
PYH1_k127_5058754_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 515.0
PYH1_k127_5058754_1 ATPase (AAA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 394.0
PYH1_k127_5058754_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 339.0
PYH1_k127_5058754_3 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 301.0
PYH1_k127_5058754_4 FR47-like protein - - - 0.0000000000000000000000000001126 117.0
PYH1_k127_5058754_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000001981 118.0
PYH1_k127_5074700_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 8.094e-293 919.0
PYH1_k127_5074700_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.094e-224 704.0
PYH1_k127_5074700_10 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000003685 64.0
PYH1_k127_5074700_11 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000008005 72.0
PYH1_k127_5074700_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 604.0
PYH1_k127_5074700_3 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 576.0
PYH1_k127_5074700_4 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 484.0
PYH1_k127_5074700_5 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 297.0
PYH1_k127_5074700_6 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005103 276.0
PYH1_k127_5074700_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000002793 190.0
PYH1_k127_5074700_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000184 95.0
PYH1_k127_5074700_9 response regulator - - - 0.00000000005471 70.0
PYH1_k127_5092095_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003157 282.0
PYH1_k127_5092095_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002385 242.0
PYH1_k127_5092095_2 UPF0761 membrane protein K07058 - - 0.000000000000003956 91.0
PYH1_k127_5092095_3 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000004185 79.0
PYH1_k127_5092095_4 ABC-type multidrug transport system ATPase component - - - 0.000000000001788 79.0
PYH1_k127_5092095_5 - - - - 0.0000263 52.0
PYH1_k127_5102577_0 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.0 1278.0
PYH1_k127_5102577_1 DNA methylase K07316 - 2.1.1.72 2.811e-231 733.0
PYH1_k127_5102577_10 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000005055 165.0
PYH1_k127_5102577_11 methylamine metabolic process - - - 0.0000000000000000000000000000000000001642 147.0
PYH1_k127_5102577_12 Belongs to the Fur family K09825 - - 0.0000000000000000000000000001056 119.0
PYH1_k127_5102577_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.000000000000000000000000001195 124.0
PYH1_k127_5102577_14 Transposase and inactivated derivatives - - - 0.000000000000001979 81.0
PYH1_k127_5102577_15 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000004083 89.0
PYH1_k127_5102577_16 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.000000000003343 79.0
PYH1_k127_5102577_17 COG2202 FOG PAS PAC domain - - - 0.000000001154 72.0
PYH1_k127_5102577_18 histidine kinase A domain protein - - - 0.0006568 53.0
PYH1_k127_5102577_2 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 496.0
PYH1_k127_5102577_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 480.0
PYH1_k127_5102577_4 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 417.0
PYH1_k127_5102577_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000004549 234.0
PYH1_k127_5102577_6 HTH-like domain - - - 0.00000000000000000000000000000000000000000000000000000003973 205.0
PYH1_k127_5102577_7 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000002418 214.0
PYH1_k127_5102577_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000002477 182.0
PYH1_k127_5102577_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000001116 171.0
PYH1_k127_5118235_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 300.0
PYH1_k127_5118235_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004756 285.0
PYH1_k127_5118235_2 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005688 280.0
PYH1_k127_5118235_3 Dehydrogenase K00111,K15736 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000001262 201.0
PYH1_k127_5118235_4 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000188 157.0
PYH1_k127_5118235_5 - - - - 0.000000000000000000000000000000002706 133.0
PYH1_k127_5118235_6 Tetratricopeptide repeat - - - 0.0000000000000417 81.0
PYH1_k127_5125492_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 513.0
PYH1_k127_5125492_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000002506 180.0
PYH1_k127_517352_0 4Fe-4S single cluster domain K06937 - - 1.245e-240 762.0
PYH1_k127_517352_1 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000001273 171.0
PYH1_k127_517352_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000007371 143.0
PYH1_k127_517352_3 Belongs to the UPF0310 family - - - 0.0000000000000000000000000008627 117.0
PYH1_k127_517352_4 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000001033 88.0
PYH1_k127_5176004_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 551.0
PYH1_k127_5176004_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001691 282.0
PYH1_k127_5176004_2 peptidase inhibitor activity - - - 0.00000000000000000001156 104.0
PYH1_k127_5188784_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 324.0
PYH1_k127_5188784_1 CoA binding domain K06929 - - 0.00000000000000000000000000000004862 133.0
PYH1_k127_5188784_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000219 106.0
PYH1_k127_5188784_3 TIGRFAM TonB family C-terminal domain K03832 - - 0.0000000009612 71.0
PYH1_k127_5201455_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005758 287.0
PYH1_k127_5201455_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000001256 164.0
PYH1_k127_5201455_2 domain, Protein - - - 0.00000000000000000000000000000006961 142.0
PYH1_k127_5201455_3 Fungalysin metallopeptidase (M36) - - - 0.0000000000006723 83.0
PYH1_k127_5215966_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 509.0
PYH1_k127_5215966_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 458.0
PYH1_k127_5215966_2 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 432.0
PYH1_k127_5215966_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 439.0
PYH1_k127_5215966_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004465 276.0
PYH1_k127_5215966_5 acr, cog1430 K09005 - - 0.00000000000000006864 95.0
PYH1_k127_5232479_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 4.385e-199 630.0
PYH1_k127_5232479_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 477.0
PYH1_k127_5232479_10 TIGRFAM diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000005898 160.0
PYH1_k127_5232479_11 Protein of unknown function (DUF2905) - - - 0.000000000000000000509 88.0
PYH1_k127_5232479_12 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.000000000000000139 83.0
PYH1_k127_5232479_13 von Willebrand factor, type A K07114 - - 0.00000000000004501 86.0
PYH1_k127_5232479_2 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 406.0
PYH1_k127_5232479_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 395.0
PYH1_k127_5232479_4 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 404.0
PYH1_k127_5232479_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 316.0
PYH1_k127_5232479_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000524 301.0
PYH1_k127_5232479_7 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001186 239.0
PYH1_k127_5232479_8 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000008603 230.0
PYH1_k127_5232479_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000003801 153.0
PYH1_k127_5282186_0 DNA topoisomerase K02470,K02622 - 5.99.1.3 7.654e-273 852.0
PYH1_k127_5282186_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 514.0
PYH1_k127_5282186_2 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 460.0
PYH1_k127_5282186_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 322.0
PYH1_k127_5282186_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000001795 100.0
PYH1_k127_5282186_5 Domain of unknown function (DUF4912) K09942 - - 0.00000000003537 77.0
PYH1_k127_5294992_0 Glycogen debranching enzyme - - - 0.0 1490.0
PYH1_k127_5294992_1 Sulfate permease family - - - 3.692e-233 734.0
PYH1_k127_5294992_2 Alpha amylase, catalytic domain - - - 8.794e-218 714.0
PYH1_k127_5294992_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
PYH1_k127_5294992_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 327.0
PYH1_k127_5294992_5 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 322.0
PYH1_k127_5294992_7 YMGG-like Gly-zipper - - - 0.0009782 49.0
PYH1_k127_534455_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 7.277e-247 777.0
PYH1_k127_534455_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 601.0
PYH1_k127_534455_2 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 589.0
PYH1_k127_534455_3 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 366.0
PYH1_k127_534455_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 321.0
PYH1_k127_534455_5 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000277 114.0
PYH1_k127_5372281_0 Peptidase S46 - - - 1.696e-280 882.0
PYH1_k127_5372281_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 571.0
PYH1_k127_5372281_2 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000001198 233.0
PYH1_k127_5372281_3 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000000000000000007278 225.0
PYH1_k127_5372281_4 DinB family - - - 0.000000000000000000000000000000000000000004048 173.0
PYH1_k127_5372281_5 Diacylglycerol kinase catalytic domain - - - 0.000000002709 66.0
PYH1_k127_5380366_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 307.0
PYH1_k127_5380366_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003985 278.0
PYH1_k127_5416743_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1257.0
PYH1_k127_5416743_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.154e-202 649.0
PYH1_k127_5416743_10 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000001244 180.0
PYH1_k127_5416743_11 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000002069 179.0
PYH1_k127_5416743_12 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000001337 152.0
PYH1_k127_5416743_13 - - - - 0.0000000000000000007198 88.0
PYH1_k127_5416743_14 - - - - 0.0000000000009499 70.0
PYH1_k127_5416743_15 SpoVT / AbrB like domain - - - 0.00000000003746 66.0
PYH1_k127_5416743_16 Autotransporter beta-domain - - - 0.0000001936 66.0
PYH1_k127_5416743_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 378.0
PYH1_k127_5416743_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 365.0
PYH1_k127_5416743_4 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 362.0
PYH1_k127_5416743_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 346.0
PYH1_k127_5416743_6 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 330.0
PYH1_k127_5416743_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004343 286.0
PYH1_k127_5416743_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000002166 233.0
PYH1_k127_5416743_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000002326 197.0
PYH1_k127_547140_0 - - - - 0.0 1022.0
PYH1_k127_547140_1 acyl-CoA dehydrogenase - - - 9.871e-235 741.0
PYH1_k127_547140_10 Adenylate cyclase - - - 0.00000004483 60.0
PYH1_k127_547140_2 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 1.469e-194 619.0
PYH1_k127_547140_3 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 350.0
PYH1_k127_547140_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 347.0
PYH1_k127_547140_5 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 333.0
PYH1_k127_547140_6 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 319.0
PYH1_k127_547140_8 - - - - 0.00000000000000000001208 96.0
PYH1_k127_547140_9 Protein tyrosine kinase - - - 0.00000000000009751 73.0
PYH1_k127_5489151_0 lipopolysaccharide transport K22110 - - 0.0 1341.0
PYH1_k127_5489151_1 Glycogen debranching enzyme - - - 9.402e-205 671.0
PYH1_k127_5489151_10 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000133 196.0
PYH1_k127_5489151_11 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000004606 161.0
PYH1_k127_5489151_12 - - - - 0.000000000000000000000000000000009932 147.0
PYH1_k127_5489151_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000002317 93.0
PYH1_k127_5489151_14 Putative zinc-finger - - - 0.00000000257 61.0
PYH1_k127_5489151_2 choline dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 533.0
PYH1_k127_5489151_3 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 533.0
PYH1_k127_5489151_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 446.0
PYH1_k127_5489151_5 NADH dehydrogenase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 405.0
PYH1_k127_5489151_6 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 344.0
PYH1_k127_5489151_7 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 334.0
PYH1_k127_5489151_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001427 248.0
PYH1_k127_5489151_9 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000002159 239.0
PYH1_k127_5489869_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 383.0
PYH1_k127_5489869_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 355.0
PYH1_k127_5489869_2 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000003716 174.0
PYH1_k127_5489869_3 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00003569 49.0
PYH1_k127_5490445_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 402.0
PYH1_k127_5490445_1 - K00241 - - 0.00000000000000000000000000961 114.0
PYH1_k127_5495376_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.136e-195 640.0
PYH1_k127_5495376_1 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 392.0
PYH1_k127_5495376_2 CYTH K05873 - 4.6.1.1 0.00000000000000000004133 102.0
PYH1_k127_5495376_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000006875 98.0
PYH1_k127_5495376_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000003907 81.0
PYH1_k127_55344_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 7.775e-223 699.0
PYH1_k127_55344_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 4.062e-208 672.0
PYH1_k127_55344_10 metalloendopeptidase activity - - - 0.000001113 59.0
PYH1_k127_55344_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 411.0
PYH1_k127_55344_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 336.0
PYH1_k127_55344_4 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001069 282.0
PYH1_k127_55344_5 coenzyme F420 binding K07226 - - 0.0000000000000000000000000000000000000005297 157.0
PYH1_k127_55344_6 Cytochrome c - - - 0.000000000000000000000000000000000000001287 158.0
PYH1_k127_55344_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000006273 110.0
PYH1_k127_55344_8 Belongs to the ompA family K12216 - - 0.000000000000002084 86.0
PYH1_k127_554628_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 540.0
PYH1_k127_554628_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 432.0
PYH1_k127_554628_10 Stage II sporulation protein K06381 - - 0.0000000000000000000000000004008 123.0
PYH1_k127_554628_11 HD domain K07814 - - 0.000000000000000000000001874 118.0
PYH1_k127_554628_12 Spore Coat Protein - - - 0.000000000000000000000004696 108.0
PYH1_k127_554628_13 response regulator K02481 - - 0.00000000000000000000006367 102.0
PYH1_k127_554628_14 dinucleotide biosynthesis protein K03753 - - 0.00000000000000000003675 106.0
PYH1_k127_554628_15 Spore Coat Protein U domain - - - 0.0000000000000000001268 98.0
PYH1_k127_554628_16 Spore Coat Protein U domain - - - 0.0000000000000002144 93.0
PYH1_k127_554628_17 Bacterial membrane protein YfhO - - - 0.0000000001034 75.0
PYH1_k127_554628_18 Histidine kinase A domain protein - - - 0.0000000177 66.0
PYH1_k127_554628_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 362.0
PYH1_k127_554628_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 319.0
PYH1_k127_554628_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 301.0
PYH1_k127_554628_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
PYH1_k127_554628_6 Major facilitator K08223 - - 0.00000000000000000000000000000000000000000000000000000000000004215 224.0
PYH1_k127_554628_7 NlpE C-terminal OB domain - - - 0.000000000000000000000000000000000000000000001353 186.0
PYH1_k127_554628_8 pilus organization K07346 - - 0.00000000000000000000000000000000000000000009635 169.0
PYH1_k127_554628_9 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000001716 147.0
PYH1_k127_5558538_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
PYH1_k127_5558538_1 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000002207 205.0
PYH1_k127_5558538_2 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000002053 128.0
PYH1_k127_5558538_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000005871 56.0
PYH1_k127_5567713_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 454.0
PYH1_k127_5567713_1 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 428.0
PYH1_k127_5567713_2 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 330.0
PYH1_k127_5567713_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000009793 188.0
PYH1_k127_5567713_4 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000003801 139.0
PYH1_k127_5567713_5 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000001044 119.0
PYH1_k127_5569144_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005195 289.0
PYH1_k127_5569144_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000004912 226.0
PYH1_k127_5584898_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 584.0
PYH1_k127_5584898_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 554.0
PYH1_k127_5584898_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001705 249.0
PYH1_k127_5584898_3 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000001436 260.0
PYH1_k127_5584898_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000001525 122.0
PYH1_k127_5584898_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000009169 113.0
PYH1_k127_5585649_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1182.0
PYH1_k127_5585649_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000007142 128.0
PYH1_k127_5585649_2 - - - - 0.000000000000000000000002265 110.0
PYH1_k127_5719085_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000005283 244.0
PYH1_k127_5719085_1 Aminotransferase class-III - - - 0.00000000000000000000007366 115.0
PYH1_k127_5719085_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000001583 91.0
PYH1_k127_5719085_3 PFAM peptidase - - - 0.000000000000001679 87.0
PYH1_k127_576063_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1019.0
PYH1_k127_576063_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 434.0
PYH1_k127_576063_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 289.0
PYH1_k127_576063_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000001167 240.0
PYH1_k127_5800211_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001659 256.0
PYH1_k127_5800211_1 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000001768 245.0
PYH1_k127_5800211_2 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.00007471 53.0
PYH1_k127_581358_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 443.0
PYH1_k127_581358_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 426.0
PYH1_k127_581358_10 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000004681 82.0
PYH1_k127_581358_12 Tetratricopeptide repeat - - - 0.00000001441 66.0
PYH1_k127_581358_13 Domain of unknown function (DUF4339) - - - 0.0000002131 64.0
PYH1_k127_581358_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 309.0
PYH1_k127_581358_3 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 252.0
PYH1_k127_581358_4 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
PYH1_k127_581358_5 Predicted membrane protein (DUF2142) - - - 0.00000000000000000000000000000000000000000000000003511 196.0
PYH1_k127_581358_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000001305 177.0
PYH1_k127_581358_7 - - - - 0.0000000000000000000000000000000004081 140.0
PYH1_k127_581358_8 TM2 domain - - - 0.0000000000000000000009681 110.0
PYH1_k127_581358_9 PAP2 superfamily - - - 0.00000000000000005662 93.0
PYH1_k127_5887634_0 Oligopeptide transporter OPT - - - 1.995e-229 733.0
PYH1_k127_5887634_1 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000493 259.0
PYH1_k127_5887634_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000219 209.0
PYH1_k127_5887634_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000001856 175.0
PYH1_k127_5887634_4 Protein of unknown function (DUF2752) - - - 0.00000000000000425 80.0
PYH1_k127_5887634_5 - - - - 0.0000000001047 69.0
PYH1_k127_5901551_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1227.0
PYH1_k127_5901551_1 Lytic murein transglycosylase K08309 - - 0.000000000000000000000002997 109.0
PYH1_k127_5942114_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 1.056e-303 951.0
PYH1_k127_5942114_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
PYH1_k127_5942114_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000005182 243.0
PYH1_k127_5942114_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000001677 226.0
PYH1_k127_5942114_4 Regulatory protein - - - 0.00000000000000000519 93.0
PYH1_k127_5955331_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000003496 241.0
PYH1_k127_5955331_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000005834 211.0
PYH1_k127_5955331_2 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000006107 132.0
PYH1_k127_5955331_3 Transcriptional regulator - - - 0.00000000000001808 81.0
PYH1_k127_5984830_0 Belongs to the peptidase S8 family K13275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 492.0
PYH1_k127_5984830_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 458.0
PYH1_k127_5984830_10 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000002748 201.0
PYH1_k127_5984830_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000007148 173.0
PYH1_k127_5984830_12 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000000001146 176.0
PYH1_k127_5984830_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000001948 177.0
PYH1_k127_5984830_14 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000001259 162.0
PYH1_k127_5984830_15 Transcriptional regulator, Crp Fnr family K01420,K10914 - - 0.0000000000000000000000000000000000000000702 160.0
PYH1_k127_5984830_16 Vitamin B12 dependent methionine synthase activation - - - 0.000000000004505 79.0
PYH1_k127_5984830_17 Peptidoglycan-binding domain 1 protein - - - 0.00000000001063 74.0
PYH1_k127_5984830_2 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 372.0
PYH1_k127_5984830_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 310.0
PYH1_k127_5984830_4 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 309.0
PYH1_k127_5984830_5 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002994 287.0
PYH1_k127_5984830_6 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000256 276.0
PYH1_k127_5984830_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004183 271.0
PYH1_k127_5984830_8 pfam abc K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000001738 236.0
PYH1_k127_5984830_9 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000000002118 192.0
PYH1_k127_6003230_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 7.318e-277 871.0
PYH1_k127_6003230_1 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 531.0
PYH1_k127_6003230_2 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000001593 219.0
PYH1_k127_6003230_3 - - - - 0.000000000000000000000000000000000000151 149.0
PYH1_k127_6003230_4 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.00000000000000000000000000006085 122.0
PYH1_k127_6003230_5 PFAM CBS domain - - - 0.000000000000000000000000003248 123.0
PYH1_k127_6003230_6 PFAM Sodium sulfate symporter transmembrane region K14445 - - 0.0000000000000326 74.0
PYH1_k127_6020063_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.061e-201 634.0
PYH1_k127_6020063_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000151 96.0
PYH1_k127_6061299_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 408.0
PYH1_k127_6061299_1 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004471 284.0
PYH1_k127_6061299_10 antisigma factor binding - - - 0.0000000000000000000125 96.0
PYH1_k127_6061299_11 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000006632 105.0
PYH1_k127_6061299_12 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000001661 69.0
PYH1_k127_6061299_13 Aspartyl protease - - - 0.0000002293 64.0
PYH1_k127_6061299_14 Methyltransferase domain - - - 0.0000003364 61.0
PYH1_k127_6061299_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
PYH1_k127_6061299_3 electron transport chain K00347,K03614 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000001462 260.0
PYH1_k127_6061299_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000001484 218.0
PYH1_k127_6061299_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000008926 236.0
PYH1_k127_6061299_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000001552 222.0
PYH1_k127_6061299_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000001592 178.0
PYH1_k127_6061299_8 SMART phosphoesterase PA-phosphatase related - - - 0.0000000000000000000000000000000000000001262 169.0
PYH1_k127_6061299_9 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000003043 98.0
PYH1_k127_6091700_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1556.0
PYH1_k127_6091700_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1470.0
PYH1_k127_6091700_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 448.0
PYH1_k127_6091700_3 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 368.0
PYH1_k127_6091700_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005876 259.0
PYH1_k127_6091700_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000001551 183.0
PYH1_k127_6091700_6 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000005994 178.0
PYH1_k127_6091700_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000001064 129.0
PYH1_k127_6097682_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 5.417e-197 619.0
PYH1_k127_6097682_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 370.0
PYH1_k127_6097682_2 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003718 278.0
PYH1_k127_6097682_3 PFAM NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001385 233.0
PYH1_k127_6097682_4 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000537 99.0
PYH1_k127_6104462_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 536.0
PYH1_k127_6104462_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 362.0
PYH1_k127_6104462_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000351 291.0
PYH1_k127_6104462_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000003585 198.0
PYH1_k127_6104462_4 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000004765 144.0
PYH1_k127_6104462_5 Ribonuclease K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000008983 113.0
PYH1_k127_6104462_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000021 97.0
PYH1_k127_6104462_7 C4-type zinc ribbon domain K07164 - - 0.00000000000000008751 91.0
PYH1_k127_6104462_8 PFAM DivIVA family protein K04074 - - 0.000000000000001772 83.0
PYH1_k127_6104462_9 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000001596 70.0
PYH1_k127_6140501_0 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000001234 98.0
PYH1_k127_6140501_2 - - - - 0.0002068 53.0
PYH1_k127_6146512_0 PFAM Prolyl oligopeptidase family - - - 4.942e-292 930.0
PYH1_k127_6146512_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.164e-205 661.0
PYH1_k127_6146512_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 404.0
PYH1_k127_6146512_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 295.0
PYH1_k127_6146512_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000003082 223.0
PYH1_k127_6146512_5 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000001025 227.0
PYH1_k127_6146512_6 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000001472 140.0
PYH1_k127_6146512_7 Peptidase family M23 K21472 - - 0.00000000000000000000001459 115.0
PYH1_k127_6175879_0 cellulose binding - - - 4.571e-243 780.0
PYH1_k127_6175879_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.534e-213 684.0
PYH1_k127_6175879_10 Protein of unknown function (DUF2752) - - - 0.00000002668 66.0
PYH1_k127_6175879_2 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 410.0
PYH1_k127_6175879_3 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 408.0
PYH1_k127_6175879_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 327.0
PYH1_k127_6175879_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000001938 183.0
PYH1_k127_6175879_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000247 135.0
PYH1_k127_6175879_7 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000003978 141.0
PYH1_k127_6175879_8 - - - - 0.000000000000000006947 98.0
PYH1_k127_6175879_9 integral membrane protein - - - 0.000000000000000389 89.0
PYH1_k127_6188623_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
PYH1_k127_6188623_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000003968 191.0
PYH1_k127_6188623_2 ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000001692 184.0
PYH1_k127_6188623_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000001287 153.0
PYH1_k127_6188623_4 outer membrane efflux protein - - - 0.0000000000000000000000002976 119.0
PYH1_k127_6289375_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 395.0
PYH1_k127_6289375_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 383.0
PYH1_k127_6289375_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000004234 223.0
PYH1_k127_6289375_3 von Willebrand factor, type A - - - 0.000000000000000000001203 106.0
PYH1_k127_6289375_4 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000001204 93.0
PYH1_k127_6289375_5 Thrombospondin type 3 repeat K03286 - - 0.000000000000002056 84.0
PYH1_k127_6347048_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 529.0
PYH1_k127_6347048_1 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000803 173.0
PYH1_k127_6347048_2 - - - - 0.0001171 48.0
PYH1_k127_6348341_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 382.0
PYH1_k127_6348341_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000179 198.0
PYH1_k127_6348341_2 Domain of unknown function (DUF4136) - - - 0.000000000000000000000007154 110.0
PYH1_k127_6348341_3 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000008253 65.0
PYH1_k127_6348341_4 PFAM Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00001098 48.0
PYH1_k127_6348658_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 1.992e-292 915.0
PYH1_k127_6348658_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000007628 119.0
PYH1_k127_6399855_0 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 333.0
PYH1_k127_6399855_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 320.0
PYH1_k127_6399855_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 301.0
PYH1_k127_6399855_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 304.0
PYH1_k127_6399855_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001624 239.0
PYH1_k127_6399855_5 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000003072 87.0
PYH1_k127_6399855_6 Protein of unknown function (DUF1634) - - - 0.000000000000000004989 97.0
PYH1_k127_6399855_7 (FHA) domain - - - 0.000000000003095 73.0
PYH1_k127_6399855_8 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000002448 68.0
PYH1_k127_6416139_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 541.0
PYH1_k127_6416139_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 405.0
PYH1_k127_6416139_10 PIN domain - - - 0.000002163 57.0
PYH1_k127_6416139_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 373.0
PYH1_k127_6416139_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 360.0
PYH1_k127_6416139_4 belongs to the thioredoxin family K20444,K20543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004156 276.0
PYH1_k127_6416139_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000002957 141.0
PYH1_k127_6416139_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000016 132.0
PYH1_k127_6416139_7 belongs to the thioredoxin family K20444,K20543 - - 0.000000000000000000006581 106.0
PYH1_k127_6416139_8 PFAM glycosyl transferase family 39 - - - 0.00000000000000002353 92.0
PYH1_k127_6416139_9 positive regulation of growth - - - 0.0000000001202 65.0
PYH1_k127_6508820_0 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 346.0
PYH1_k127_6508820_1 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 326.0
PYH1_k127_6508820_2 transporter, DctM subunit K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 308.0
PYH1_k127_6508820_3 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000005075 187.0
PYH1_k127_6508820_5 Belongs to the pirin family K06911 - - 0.000002417 53.0
PYH1_k127_6508820_6 aldo keto reductase - - - 0.0005123 43.0
PYH1_k127_651576_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1139.0
PYH1_k127_651576_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 519.0
PYH1_k127_651576_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001791 224.0
PYH1_k127_651576_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000287 243.0
PYH1_k127_651576_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000003823 119.0
PYH1_k127_651576_5 integral membrane protein - - - 0.0000000000000001099 92.0
PYH1_k127_651576_6 Methyltransferase domain - - - 0.0000000003993 73.0
PYH1_k127_651576_7 CopG domain protein DNA-binding domain protein - - - 0.0000000008919 62.0
PYH1_k127_6575602_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 404.0
PYH1_k127_6575602_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 392.0
PYH1_k127_6575602_2 ABC transporter C-terminal domain K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 373.0
PYH1_k127_6575602_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000001136 130.0
PYH1_k127_658662_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 308.0
PYH1_k127_658662_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000005077 138.0
PYH1_k127_658662_2 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000003829 61.0
PYH1_k127_658662_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000166 52.0
PYH1_k127_6649716_0 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 426.0
PYH1_k127_6649716_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 404.0
PYH1_k127_6649716_2 uroporphyrinogen decarboxylase activity K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 313.0
PYH1_k127_6649716_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 295.0
PYH1_k127_6649716_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000791 249.0
PYH1_k127_6649716_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000005838 221.0
PYH1_k127_6649716_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000004799 157.0
PYH1_k127_6649716_7 ABC-type transport system involved in cytochrome c biogenesis, permease component K02497 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.000000007554 66.0
PYH1_k127_6719611_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 563.0
PYH1_k127_6719611_1 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000001493 288.0
PYH1_k127_6719611_2 Spore Coat K01790 - 5.1.3.13 0.000000000000000000000000000000405 131.0
PYH1_k127_6719611_3 Belongs to the universal stress protein A family - - - 0.0000000000000000005079 93.0
PYH1_k127_6719611_4 Protein of unknown function (DUF2723) - - - 0.00001622 58.0
PYH1_k127_6719829_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 439.0
PYH1_k127_6719829_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 334.0
PYH1_k127_6719829_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009024 288.0
PYH1_k127_6719829_3 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002236 283.0
PYH1_k127_6719829_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.0002645 47.0
PYH1_k127_6719829_5 Thioredoxin-like - - - 0.0004972 46.0
PYH1_k127_6722728_0 COG NOG10142 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 526.0
PYH1_k127_6722728_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 508.0
PYH1_k127_6722728_2 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 393.0
PYH1_k127_6722728_3 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 400.0
PYH1_k127_6722728_5 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000009474 177.0
PYH1_k127_6722728_6 - - - - 0.00000000000000396 81.0
PYH1_k127_6722728_7 Glycine-zipper domain - - - 0.000005071 50.0
PYH1_k127_6723359_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 522.0
PYH1_k127_6723359_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 404.0
PYH1_k127_6723359_2 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 325.0
PYH1_k127_6723359_3 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000006 199.0
PYH1_k127_6723359_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000005932 153.0
PYH1_k127_6723359_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000002439 135.0
PYH1_k127_6723359_6 Major facilitator K08223 - - 0.00000000000000007427 81.0
PYH1_k127_6773017_0 PFAM FAD linked oxidase domain protein - - - 1.355e-198 634.0
PYH1_k127_6773017_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 500.0
PYH1_k127_6773017_2 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 423.0
PYH1_k127_6773017_3 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000002416 241.0
PYH1_k127_6773017_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000005159 139.0
PYH1_k127_6773017_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000009584 108.0
PYH1_k127_6773017_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000008194 63.0
PYH1_k127_6773017_7 - - - - 0.00000001397 59.0
PYH1_k127_6773017_8 PFAM GCN5-related N-acetyltransferase - - - 0.0000004915 61.0
PYH1_k127_6773017_9 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0008684 44.0
PYH1_k127_6785278_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 437.0
PYH1_k127_6785278_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00003313 52.0
PYH1_k127_6796979_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 355.0
PYH1_k127_6796979_1 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000006299 220.0
PYH1_k127_6796979_2 of the beta-lactamase K00784 - 3.1.26.11 0.0000000000000000000000000000000000000008003 158.0
PYH1_k127_6796979_3 Methyltransferase - - - 0.000000000000000000000002568 114.0
PYH1_k127_6807924_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1221.0
PYH1_k127_6807924_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 593.0
PYH1_k127_6807924_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 454.0
PYH1_k127_6807924_3 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 428.0
PYH1_k127_6807924_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000004118 99.0
PYH1_k127_6807924_6 Domain of unknown function (DUF3943) - - - 0.00000008204 61.0
PYH1_k127_6807924_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000002855 60.0
PYH1_k127_6807924_8 COG NOG22668 non supervised orthologous group - - - 0.000003302 53.0
PYH1_k127_6807924_9 toxin-antitoxin pair type II binding K06284 - - 0.00001315 51.0
PYH1_k127_6828635_0 PFAM response regulator receiver K07713 - - 1.259e-199 632.0
PYH1_k127_6828635_1 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 487.0
PYH1_k127_6828635_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 363.0
PYH1_k127_6828635_3 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000001771 170.0
PYH1_k127_6828635_4 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000000104 68.0
PYH1_k127_6831009_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 546.0
PYH1_k127_6831009_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 398.0
PYH1_k127_6831009_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000001517 234.0
PYH1_k127_6841315_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 515.0
PYH1_k127_6841315_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 418.0
PYH1_k127_6841315_2 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 326.0
PYH1_k127_6841315_3 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 322.0
PYH1_k127_6841315_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 310.0
PYH1_k127_6841315_5 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000001053 196.0
PYH1_k127_6841315_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000005033 83.0
PYH1_k127_6860738_0 Integrase core domain - - - 0.00000000000000000000002972 102.0
PYH1_k127_6860738_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000001895 103.0
PYH1_k127_6860738_2 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.00000008748 66.0
PYH1_k127_6866746_0 Sortilin, neurotensin receptor 3, - - - 0.0 1210.0
PYH1_k127_6866746_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 413.0
PYH1_k127_6866746_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
PYH1_k127_6866746_3 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000001072 134.0
PYH1_k127_6882916_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 438.0
PYH1_k127_6882916_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000001282 152.0
PYH1_k127_6882916_2 Aminotransferase class I and II K11358 - 2.6.1.1 0.00000000000003167 85.0
PYH1_k127_6887460_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
PYH1_k127_6887460_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005883 255.0
PYH1_k127_6887460_2 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000001884 196.0
PYH1_k127_6887460_3 Histidine kinase K07652 - 2.7.13.3 0.00000000000000000000008069 105.0
PYH1_k127_6887460_4 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000002234 108.0
PYH1_k127_6892549_0 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 402.0
PYH1_k127_6892549_1 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000001977 205.0
PYH1_k127_6892549_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000003216 188.0
PYH1_k127_6892549_3 - - - - 0.0000000000000000000000002022 116.0
PYH1_k127_6892549_4 Preprotein translocase SecG subunit K03075 - - 0.00000000000001025 81.0
PYH1_k127_6892549_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000002088 75.0
PYH1_k127_6892549_6 RDD family - - - 0.000001652 60.0
PYH1_k127_6892549_7 Belongs to the BshC family K22136 - - 0.000002815 55.0
PYH1_k127_6892549_8 response to antibiotic - - - 0.0002329 50.0
PYH1_k127_6900157_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1173.0
PYH1_k127_6900157_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 343.0
PYH1_k127_6900157_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003348 177.0
PYH1_k127_6900157_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000001252 174.0
PYH1_k127_6900157_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000007055 160.0
PYH1_k127_6900157_13 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000001655 153.0
PYH1_k127_6900157_14 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000003784 145.0
PYH1_k127_6900157_15 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000001194 139.0
PYH1_k127_6900157_16 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.0000000000000000000000000000000009929 139.0
PYH1_k127_6900157_17 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000008741 145.0
PYH1_k127_6900157_18 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000004177 106.0
PYH1_k127_6900157_19 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002839 82.0
PYH1_k127_6900157_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 339.0
PYH1_k127_6900157_20 - - - - 0.00000002577 61.0
PYH1_k127_6900157_21 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000001244 57.0
PYH1_k127_6900157_23 Periplasmic binding protein LacI transcriptional regulator K01775,K02529 - 5.1.1.1 0.0003852 45.0
PYH1_k127_6900157_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 317.0
PYH1_k127_6900157_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003463 299.0
PYH1_k127_6900157_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007261 284.0
PYH1_k127_6900157_6 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000529 228.0
PYH1_k127_6900157_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002566 226.0
PYH1_k127_6900157_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000001654 208.0
PYH1_k127_6900157_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000002496 184.0
PYH1_k127_6911858_0 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 330.0
PYH1_k127_6911858_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006853 243.0
PYH1_k127_6911858_2 - - - - 0.000000000000004783 87.0
PYH1_k127_6911858_3 Rhodanese Homology Domain K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000001892 62.0
PYH1_k127_693420_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 442.0
PYH1_k127_693420_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 311.0
PYH1_k127_693420_2 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000001324 184.0
PYH1_k127_693420_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000008884 149.0
PYH1_k127_6997674_0 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 523.0
PYH1_k127_6997674_1 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 486.0
PYH1_k127_6997674_10 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0004832 49.0
PYH1_k127_6997674_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000001032 199.0
PYH1_k127_6997674_3 phosphatase activity K07025 - - 0.0000000000000000000000000000000000001232 156.0
PYH1_k127_6997674_4 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000006655 149.0
PYH1_k127_6997674_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000001055 145.0
PYH1_k127_6997674_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000003501 72.0
PYH1_k127_6997674_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000006427 73.0
PYH1_k127_6997674_8 PIN domain K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000002107 69.0
PYH1_k127_6997674_9 ABC-2 type transporter K01992 - - 0.000002454 61.0
PYH1_k127_7007776_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1701.0
PYH1_k127_7007776_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.148e-202 639.0
PYH1_k127_7011858_0 Prolyl oligopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 556.0
PYH1_k127_7011858_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 479.0
PYH1_k127_7011858_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 373.0
PYH1_k127_7011858_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 327.0
PYH1_k127_7011858_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 326.0
PYH1_k127_7011858_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000397 227.0
PYH1_k127_7011858_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000001435 187.0
PYH1_k127_7011858_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000006776 95.0
PYH1_k127_7011858_8 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000009214 92.0
PYH1_k127_7011858_9 - - - - 0.000003077 57.0
PYH1_k127_7023955_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 574.0
PYH1_k127_7023955_1 4Fe-4S binding domain - - - 0.0000000000000000000000000002248 115.0
PYH1_k127_7035813_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 609.0
PYH1_k127_7035813_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 471.0
PYH1_k127_7035813_2 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 407.0
PYH1_k127_7035813_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 390.0
PYH1_k127_7035813_4 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000002101 157.0
PYH1_k127_7036009_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.922e-301 940.0
PYH1_k127_7036009_1 Elongation factor Tu C-terminal domain K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.431e-196 616.0
PYH1_k127_7036009_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000003835 92.0
PYH1_k127_7036009_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 412.0
PYH1_k127_7036009_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 380.0
PYH1_k127_7036009_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003927 240.0
PYH1_k127_7036009_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
PYH1_k127_7036009_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000003341 220.0
PYH1_k127_7036009_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000008101 161.0
PYH1_k127_7036009_8 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001015 162.0
PYH1_k127_7036009_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000008487 134.0
PYH1_k127_7036754_0 lipolytic protein G-D-S-L family - - - 0.000000000001583 79.0
PYH1_k127_7036754_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0004606 54.0
PYH1_k127_7062299_0 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 308.0
PYH1_k127_7062299_1 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006812 280.0
PYH1_k127_7062299_2 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000001675 209.0
PYH1_k127_7062299_3 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000002031 60.0
PYH1_k127_7071393_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 308.0
PYH1_k127_7071393_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007214 267.0
PYH1_k127_7071393_2 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000006809 174.0
PYH1_k127_7071393_3 methyltransferase activity - - - 0.00000000000000000000000000000004528 132.0
PYH1_k127_7071393_4 - - - - 0.0000000000002158 74.0
PYH1_k127_7071393_5 OsmC-like protein - - - 0.00000109 53.0
PYH1_k127_7104166_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 408.0
PYH1_k127_7104166_1 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002667 259.0
PYH1_k127_7104166_3 AAA domain - - - 0.0000000000000000000000000000000000000000000000000005154 190.0
PYH1_k127_7104166_4 thiolester hydrolase activity K06889 - - 0.0000000005757 72.0
PYH1_k127_7105899_0 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 361.0
PYH1_k127_7105899_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000001201 141.0
PYH1_k127_7105899_2 Lipopolysaccharide kinase (Kdo/WaaP) family K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000001836 149.0
PYH1_k127_7105899_3 2Fe-2S -binding domain - - - 0.0000000005909 65.0
PYH1_k127_7105899_4 Thioredoxin-like - - - 0.0003094 52.0
PYH1_k127_7133272_0 Proprotein convertase P-domain - - - 1.269e-282 888.0
PYH1_k127_7133272_1 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 466.0
PYH1_k127_7133272_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 431.0
PYH1_k127_7133272_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 354.0
PYH1_k127_7133272_4 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 362.0
PYH1_k127_7133272_5 esterase - - - 0.0000000000000000000000000000000000000000000000000000000001183 225.0
PYH1_k127_7133272_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000004101 203.0
PYH1_k127_7133272_7 protein kinase activity - - - 0.0000000000000000000000009196 121.0
PYH1_k127_7133272_8 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000001476 98.0
PYH1_k127_7133272_9 Putative phosphatase (DUF442) - - - 0.000000000000000004505 95.0
PYH1_k127_7155967_0 elongation factor G K02355 - - 8.483e-200 643.0
PYH1_k127_7155967_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006559 284.0
PYH1_k127_7155967_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000618 265.0
PYH1_k127_7155967_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000001236 251.0
PYH1_k127_7155967_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000004036 181.0
PYH1_k127_7155967_5 response to nickel cation - - - 0.00000000001512 67.0
PYH1_k127_7155967_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000009336 72.0
PYH1_k127_7159655_0 signal transduction histidine kinase - - - 0.00000000000000000000003035 110.0
PYH1_k127_7159655_1 Belongs to the glycosyl hydrolase 13 family K01176 - 3.2.1.1 0.00000000000001109 77.0
PYH1_k127_7159655_2 - - - - 0.000004199 50.0
PYH1_k127_7211517_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1639.0
PYH1_k127_7211517_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1144.0
PYH1_k127_7211517_10 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000008463 208.0
PYH1_k127_7211517_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000003511 196.0
PYH1_k127_7211517_12 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000004805 158.0
PYH1_k127_7211517_13 DinB family - - - 0.00000000000000000000000000000000000001896 153.0
PYH1_k127_7211517_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000007626 144.0
PYH1_k127_7211517_15 acyl-coa-binding protein - - - 0.000000000000000000000000000115 118.0
PYH1_k127_7211517_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000002 124.0
PYH1_k127_7211517_17 cell wall organization - - - 0.00000000000000000002494 104.0
PYH1_k127_7211517_18 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000383 80.0
PYH1_k127_7211517_19 KaiC - - - 0.00000005572 65.0
PYH1_k127_7211517_2 Hydrolase CocE NonD family - - - 4.165e-321 1000.0
PYH1_k127_7211517_3 SMART Elongator protein 3 MiaB NifB - - - 1.586e-211 672.0
PYH1_k127_7211517_4 PFAM Acetyl-CoA dehydrogenase-like C-terminal domain, Acyl-CoA dehydrogenase domain-containing protein, acyl-CoA dehydrogenase domain-containing protein K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 492.0
PYH1_k127_7211517_5 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 389.0
PYH1_k127_7211517_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 335.0
PYH1_k127_7211517_7 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 293.0
PYH1_k127_7211517_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000009409 241.0
PYH1_k127_7211517_9 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000001178 213.0
PYH1_k127_7239415_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 8.279e-201 633.0
PYH1_k127_7239415_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 589.0
PYH1_k127_7239415_10 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000002647 219.0
PYH1_k127_7239415_11 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003425 211.0
PYH1_k127_7239415_12 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000002082 209.0
PYH1_k127_7239415_13 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000001465 189.0
PYH1_k127_7239415_14 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000001365 190.0
PYH1_k127_7239415_15 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000008474 169.0
PYH1_k127_7239415_16 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000001664 142.0
PYH1_k127_7239415_17 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000001058 124.0
PYH1_k127_7239415_18 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000001331 125.0
PYH1_k127_7239415_19 PFAM Redoxin - - - 0.00000000000000000000002339 115.0
PYH1_k127_7239415_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 599.0
PYH1_k127_7239415_20 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000008271 80.0
PYH1_k127_7239415_21 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000002095 78.0
PYH1_k127_7239415_22 PFAM phosphatidate cytidylyltransferase - - - 0.00004944 57.0
PYH1_k127_7239415_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 396.0
PYH1_k127_7239415_4 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 364.0
PYH1_k127_7239415_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 343.0
PYH1_k127_7239415_6 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 323.0
PYH1_k127_7239415_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 300.0
PYH1_k127_7239415_8 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000002101 240.0
PYH1_k127_7239415_9 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000002966 224.0
PYH1_k127_7269374_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 602.0
PYH1_k127_7269374_1 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 536.0
PYH1_k127_7269374_10 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000002456 166.0
PYH1_k127_7269374_11 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000001649 151.0
PYH1_k127_7269374_12 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000001119 143.0
PYH1_k127_7269374_13 Hfq protein - - - 0.00000000000000000000000002234 125.0
PYH1_k127_7269374_14 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000000000008691 114.0
PYH1_k127_7269374_15 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K10794 - 1.21.4.1,1.21.4.2 0.000000000000001057 79.0
PYH1_k127_7269374_16 DinB superfamily - - - 0.00000000000002011 81.0
PYH1_k127_7269374_17 Lipid A 3-O-deacylase (PagL) - - - 0.00000221 58.0
PYH1_k127_7269374_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 374.0
PYH1_k127_7269374_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 360.0
PYH1_k127_7269374_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 351.0
PYH1_k127_7269374_5 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 347.0
PYH1_k127_7269374_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000006372 236.0
PYH1_k127_7269374_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000757 229.0
PYH1_k127_7283205_0 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 313.0
PYH1_k127_7283205_1 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.000000175 64.0
PYH1_k127_7283205_2 Prokaryotic N-terminal methylation motif - - - 0.0001665 55.0
PYH1_k127_7315850_0 GTP1/OBG K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 339.0
PYH1_k127_7315850_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000008107 178.0
PYH1_k127_7315850_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000001436 136.0
PYH1_k127_7315850_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000002832 108.0
PYH1_k127_7315850_4 TPM domain - - - 0.000000000000000000001081 107.0
PYH1_k127_7380362_0 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 593.0
PYH1_k127_7380362_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000003667 240.0
PYH1_k127_7380362_2 PFAM Alpha beta hydrolase K07019 - - 0.00000000000000000000000000000000000000000000000000000000000211 241.0
PYH1_k127_7380362_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000002604 198.0
PYH1_k127_7380362_4 Transcriptional regulator - - - 0.0007193 49.0
PYH1_k127_7415916_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1253.0
PYH1_k127_7415916_1 translation initiation factor activity K07004,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 370.0
PYH1_k127_7415916_2 Transcriptional regulator - - - 0.0000005882 63.0
PYH1_k127_7415916_3 Sigma-70, region 4 - - - 0.000007295 55.0
PYH1_k127_7415916_4 Tetratricopeptide repeat - - - 0.0002304 55.0
PYH1_k127_7415916_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0005214 50.0
PYH1_k127_7420978_0 PFAM Prolyl oligopeptidase family - - - 1.495e-240 767.0
PYH1_k127_7420978_1 imidazolonepropionase activity K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008401 293.0
PYH1_k127_7420978_2 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000002196 167.0
PYH1_k127_7420978_3 Transcription elongation factor, N-terminal - - - 0.000000000000000000000000000002957 139.0
PYH1_k127_7420978_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000213 69.0
PYH1_k127_7432439_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 394.0
PYH1_k127_7432439_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 313.0
PYH1_k127_7432439_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 304.0
PYH1_k127_7432439_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000008129 224.0
PYH1_k127_7432439_4 NUDIX domain - - - 0.00000000000000000000000000000000000000001285 161.0
PYH1_k127_7432439_5 Tetratricopeptide repeat - - - 0.0000000003368 71.0
PYH1_k127_7432439_6 Sporulation related domain K03749 - - 0.0001171 52.0
PYH1_k127_7455285_0 ABC transporter transmembrane K11085 - - 2.746e-250 808.0
PYH1_k127_7455285_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 511.0
PYH1_k127_7455285_10 PFAM glycosyl transferase family 2 - - - 0.00000006814 63.0
PYH1_k127_7455285_11 Male sterility protein K01784,K19997 - 5.1.3.2,5.1.3.26 0.0000524 56.0
PYH1_k127_7455285_2 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 417.0
PYH1_k127_7455285_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 360.0
PYH1_k127_7455285_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
PYH1_k127_7455285_5 saccharopine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 328.0
PYH1_k127_7455285_6 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000005809 210.0
PYH1_k127_7455285_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000163 191.0
PYH1_k127_7455285_8 peptidyl-tyrosine sulfation - - - 0.000000000000001166 87.0
PYH1_k127_7455285_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000003696 70.0
PYH1_k127_749269_0 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 349.0
PYH1_k127_749269_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
PYH1_k127_749269_2 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004164 265.0
PYH1_k127_749269_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000001461 143.0
PYH1_k127_749269_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000001491 115.0
PYH1_k127_7532954_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1000.0
PYH1_k127_7532954_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 394.0
PYH1_k127_7532954_2 aminotransferase K00817 - 2.6.1.9 0.00009277 45.0
PYH1_k127_7551815_0 serine-type peptidase activity K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 429.0
PYH1_k127_7551815_1 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007759 269.0
PYH1_k127_7551815_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 252.0
PYH1_k127_7556091_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 484.0
PYH1_k127_7556091_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002489 298.0
PYH1_k127_7563142_0 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 362.0
PYH1_k127_7563142_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000003893 194.0
PYH1_k127_7569612_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.2 1.191e-241 756.0
PYH1_k127_7569612_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 3.246e-221 701.0
PYH1_k127_7586957_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 397.0
PYH1_k127_7586957_1 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000002957 241.0
PYH1_k127_7586957_2 Fe-S protein K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000005954 202.0
PYH1_k127_7586957_3 permease - - - 0.0000000000000000000000000000000000000000000001804 184.0
PYH1_k127_7588214_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 578.0
PYH1_k127_7588214_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 394.0
PYH1_k127_7588214_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000053 240.0
PYH1_k127_7588214_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000007365 186.0
PYH1_k127_7588214_4 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000001287 177.0
PYH1_k127_7588214_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000007937 171.0
PYH1_k127_7588214_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000002132 137.0
PYH1_k127_7588214_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000191 121.0
PYH1_k127_7588214_8 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0001006 46.0
PYH1_k127_7626913_0 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 383.0
PYH1_k127_7626913_1 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000004872 216.0
PYH1_k127_7626913_2 PFAM TonB-dependent Receptor Plug - - - 0.0000000000002869 76.0
PYH1_k127_7626913_3 Carboxypeptidase regulatory-like domain - - - 0.0000000265 61.0
PYH1_k127_7627471_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 393.0
PYH1_k127_7627471_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 319.0
PYH1_k127_7627471_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000002652 279.0
PYH1_k127_7627471_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000002701 218.0
PYH1_k127_7627471_4 Preprotein translocase SecG subunit K03075 - - 0.00000000000000334 81.0
PYH1_k127_7627471_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000005897 76.0
PYH1_k127_7646020_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 428.0
PYH1_k127_7646020_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 361.0
PYH1_k127_7646020_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000007078 163.0
PYH1_k127_7646020_11 - - - - 0.00000000000000000000000003834 123.0
PYH1_k127_7646020_12 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000004395 106.0
PYH1_k127_7646020_14 toxin-antitoxin pair type II binding - - - 0.000000000000006788 81.0
PYH1_k127_7646020_15 YMGG-like Gly-zipper - - - 0.0000000001607 66.0
PYH1_k127_7646020_16 toxin-antitoxin pair type II binding K06284 - - 0.000008651 57.0
PYH1_k127_7646020_17 permease - - - 0.0003094 52.0
PYH1_k127_7646020_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 328.0
PYH1_k127_7646020_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 325.0
PYH1_k127_7646020_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 310.0
PYH1_k127_7646020_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
PYH1_k127_7646020_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000006848 250.0
PYH1_k127_7646020_7 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000004472 254.0
PYH1_k127_7646020_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000465 231.0
PYH1_k127_7646020_9 dna-binding protein - - - 0.0000000000000000000000000000000000000000000000000001617 188.0
PYH1_k127_7676200_0 Putative modulator of DNA gyrase K03568 - - 2.221e-232 751.0
PYH1_k127_7676200_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 4.837e-214 671.0
PYH1_k127_7676200_10 - - - - 0.00000000000000000000009247 109.0
PYH1_k127_7676200_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000001007 97.0
PYH1_k127_7676200_12 conserved protein (COG2071) K09166 - - 0.00000000000000287 76.0
PYH1_k127_7676200_13 - - - - 0.0000000003617 65.0
PYH1_k127_7676200_14 Domain of unknown function (DUF4437) - - - 0.000000001389 71.0
PYH1_k127_7676200_15 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000993 61.0
PYH1_k127_7676200_16 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000001639 62.0
PYH1_k127_7676200_17 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000001425 55.0
PYH1_k127_7676200_18 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00002915 54.0
PYH1_k127_7676200_19 - - - - 0.0005817 44.0
PYH1_k127_7676200_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 545.0
PYH1_k127_7676200_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 452.0
PYH1_k127_7676200_4 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 408.0
PYH1_k127_7676200_5 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 396.0
PYH1_k127_7676200_6 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000007302 245.0
PYH1_k127_7676200_7 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000003569 242.0
PYH1_k127_7676200_8 NTPase - - - 0.000000000000000000000000000000000000000001496 161.0
PYH1_k127_7676200_9 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000007069 117.0
PYH1_k127_7694776_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 527.0
PYH1_k127_7694776_1 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 320.0
PYH1_k127_7694776_2 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000005664 204.0
PYH1_k127_7694776_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000003367 191.0
PYH1_k127_7694776_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000001036 131.0
PYH1_k127_7694776_5 Zincin-like metallopeptidase - - - 0.0000000000000000000004348 109.0
PYH1_k127_7713279_0 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 543.0
PYH1_k127_7713279_1 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000002802 183.0
PYH1_k127_7713279_2 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000001022 164.0
PYH1_k127_7713279_3 - - - - 0.00000000000000000000000000000000000008698 150.0
PYH1_k127_7713279_4 Protein of unknown function (DUF2723) - - - 0.0000000000004955 83.0
PYH1_k127_7743145_0 PAS sensor protein K13243 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008144,GO:0008150,GO:0009628,GO:0016787,GO:0016788,GO:0019825,GO:0019826,GO:0020037,GO:0036094,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0070482,GO:0071111,GO:0097159,GO:1901363 3.1.4.52 0.0 1028.0
PYH1_k127_7743145_1 beta-lactamase - - - 1.317e-222 716.0
PYH1_k127_7743145_2 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 454.0
PYH1_k127_7743145_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 394.0
PYH1_k127_7743145_4 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009301 277.0
PYH1_k127_7743145_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000321 250.0
PYH1_k127_7743145_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000006621 209.0
PYH1_k127_7743145_7 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000003846 153.0
PYH1_k127_7743145_8 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000009203 117.0
PYH1_k127_7743145_9 PFAM CAAX amino terminal protease family - - - 0.000000000000000000008825 105.0
PYH1_k127_7802922_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 512.0
PYH1_k127_7802922_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 308.0
PYH1_k127_7802922_2 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 299.0
PYH1_k127_7802922_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000002383 191.0
PYH1_k127_7802922_4 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000003963 175.0
PYH1_k127_7802922_5 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000001415 171.0
PYH1_k127_7802922_6 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000002707 133.0
PYH1_k127_7802922_7 Sigma-70 region 2 K03088 - - 0.0000000000000000000000002227 117.0
PYH1_k127_7802922_8 Heavy-metal resistance - - - 0.0000000000000000008304 92.0
PYH1_k127_7802922_9 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000003134 85.0
PYH1_k127_7816471_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 332.0
PYH1_k127_7816471_1 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 288.0
PYH1_k127_7816471_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000009286 252.0
PYH1_k127_7816471_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000002509 115.0
PYH1_k127_7827487_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000003833 136.0
PYH1_k127_7827487_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000005266 119.0
PYH1_k127_7827487_2 Parallel beta-helix repeats - - - 0.000000000007128 73.0
PYH1_k127_7833889_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009558 248.0
PYH1_k127_7833889_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000004761 238.0
PYH1_k127_7833889_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000000000000005007 209.0
PYH1_k127_7833889_3 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.000000000000000000000000000000000000000000000000000009616 195.0
PYH1_k127_7833889_4 - - - - 0.0000000000000000000000000000000000000000002237 163.0
PYH1_k127_7833889_5 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000006306 147.0
PYH1_k127_7833889_6 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000008651 94.0
PYH1_k127_7833889_7 META domain K03668 - - 0.000000000000007002 81.0
PYH1_k127_7833889_8 surface antigen variable number repeat protein K07001 - - 0.00000000002567 70.0
PYH1_k127_783637_0 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 517.0
PYH1_k127_783637_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 393.0
PYH1_k127_783637_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 344.0
PYH1_k127_783637_3 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 290.0
PYH1_k127_783637_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000005243 66.0
PYH1_k127_783637_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0009687 42.0
PYH1_k127_7838072_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 398.0
PYH1_k127_7838072_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001937 295.0
PYH1_k127_7838072_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000007688 265.0
PYH1_k127_7838072_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000001068 242.0
PYH1_k127_7844442_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000009678 130.0
PYH1_k127_7844442_1 - - - - 0.00001416 56.0
PYH1_k127_7858249_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5e-324 1007.0
PYH1_k127_7858249_1 Fumarase C C-terminus K01744 - 4.3.1.1 3.231e-211 666.0
PYH1_k127_7858249_2 Predicted Permease Membrane Region - - - 6.681e-210 666.0
PYH1_k127_7858249_3 Inorganic ion transport and metabolism K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 525.0
PYH1_k127_7858249_4 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000003352 248.0
PYH1_k127_7858249_5 - - - - 0.0000000000000000008358 101.0
PYH1_k127_7882752_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000288 137.0
PYH1_k127_7882752_1 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000003928 121.0
PYH1_k127_7958345_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 471.0
PYH1_k127_7958345_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 450.0
PYH1_k127_7958345_2 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000009735 211.0
PYH1_k127_7958345_3 s cog2930 - - - 0.0000000000000000000000000000000000000000000000000000001464 206.0
PYH1_k127_7958345_4 ACT domain K09707 - - 0.0000000000000000000000000000000000001752 145.0
PYH1_k127_7958345_5 - - - - 0.0000000000000000000000000000000005819 133.0
PYH1_k127_7958345_6 - - - - 0.0000000000000009189 88.0
PYH1_k127_7958345_7 - - - - 0.000005036 56.0
PYH1_k127_7958345_8 Domain of unknown function (DUF4395) - - - 0.0005947 49.0
PYH1_k127_7973934_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 379.0
PYH1_k127_7973934_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 310.0
PYH1_k127_7973934_2 selenocysteine lyase - - - 0.00000000000000000000000000002516 124.0
PYH1_k127_7973934_3 Putative ABC exporter - - - 0.000000008393 67.0
PYH1_k127_7984860_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.169e-238 747.0
PYH1_k127_7984860_1 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 499.0
PYH1_k127_7984860_10 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00004194 54.0
PYH1_k127_7984860_2 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
PYH1_k127_7984860_3 Selenocysteine synthase N terminal K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 322.0
PYH1_k127_7984860_4 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000006657 139.0
PYH1_k127_7984860_5 DSBA-like thioredoxin domain - - - 0.00000000000000000003721 103.0
PYH1_k127_7984860_6 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000001504 87.0
PYH1_k127_7984860_7 Biotin carboxyl carrier protein K01960 - 6.4.1.1 0.00000000000003479 85.0
PYH1_k127_7984860_8 Tetratricopeptide repeat - - - 0.000002223 60.0
PYH1_k127_7984860_9 domain, Protein - - - 0.000005413 55.0
PYH1_k127_7994191_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1155.0
PYH1_k127_7994191_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 332.0
PYH1_k127_7994191_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000009421 235.0
PYH1_k127_7994191_3 - - - - 0.00000000000000000000271 98.0
PYH1_k127_7994191_4 Glycosyltransferase like family 2 - - - 0.00000000000000005714 94.0
PYH1_k127_8064962_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 572.0
PYH1_k127_8064962_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000007497 178.0
PYH1_k127_8064962_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0009163 43.0
PYH1_k127_8077430_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000007966 231.0
PYH1_k127_8077430_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000003223 179.0
PYH1_k127_8077430_2 HD domain - - - 0.00000000000000000000000000000000000000000005693 181.0
PYH1_k127_8077430_3 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000004797 61.0
PYH1_k127_8078671_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 335.0
PYH1_k127_8078671_1 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000001301 228.0
PYH1_k127_8078671_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000002945 213.0
PYH1_k127_8078671_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000001009 191.0
PYH1_k127_8078671_4 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000009568 150.0
PYH1_k127_8078671_5 Gram-negative bacterial TonB protein C-terminal - - - 0.0000906 49.0
PYH1_k127_8084927_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 623.0
PYH1_k127_8084927_1 Adenylate cyclase - - - 0.000000000000000003374 93.0
PYH1_k127_8084927_2 Protein of unknown function (DUF2662) - - - 0.00000000000006073 80.0
PYH1_k127_8084927_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000276 54.0
PYH1_k127_8097359_0 aminotransferase K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000006741 230.0
PYH1_k127_8097359_1 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000001211 213.0
PYH1_k127_8097359_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000001689 95.0
PYH1_k127_8097359_3 Protein kinase domain K12132 - 2.7.11.1 0.0000002114 52.0
PYH1_k127_8097359_4 - - - - 0.00001341 53.0
PYH1_k127_8097359_5 Involved in the tonB-independent uptake of proteins - - - 0.0001618 50.0
PYH1_k127_8104690_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000001914 112.0
PYH1_k127_8104690_1 DinB superfamily - - - 0.000000000000000000000004906 111.0
PYH1_k127_8104690_2 - - - - 0.000000002137 70.0
PYH1_k127_8104690_3 HEAT repeats - - - 0.0005731 50.0
PYH1_k127_8129915_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002596 295.0
PYH1_k127_8129915_1 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000009147 94.0
PYH1_k127_8142317_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 7.456e-229 717.0
PYH1_k127_8142317_1 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000004462 244.0
PYH1_k127_8142317_2 TIGRFAM type VI secretion-associated protein, ImpA family K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000001755 241.0
PYH1_k127_8142317_3 Pfam:T6SS_VipB K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000003337 231.0
PYH1_k127_8142317_4 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000001511 208.0
PYH1_k127_8142317_5 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000002235 191.0
PYH1_k127_8142317_6 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000000001782 141.0
PYH1_k127_8142317_7 type VI secretion system effector K11903 - - 0.0000000000000000000009599 100.0
PYH1_k127_8148066_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 8.294e-221 699.0
PYH1_k127_8148066_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 516.0
PYH1_k127_8148066_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000006225 93.0
PYH1_k127_8148066_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.000000005087 68.0
PYH1_k127_8161046_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 480.0
PYH1_k127_8161046_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 349.0
PYH1_k127_8161046_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 307.0
PYH1_k127_8161046_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000008079 167.0
PYH1_k127_8161046_4 von Willebrand factor, type A - - - 0.000000000000000000000000000000006117 149.0
PYH1_k127_8161046_5 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000002112 127.0
PYH1_k127_8161046_6 nucleotidyltransferase activity K07075,K07076 - - 0.000000000000000000000000004887 117.0
PYH1_k127_8161046_7 Transposase - - - 0.00000000000000000000000009331 114.0
PYH1_k127_8161046_8 PFAM HEPN domain - - - 0.000000000000000000002094 104.0
PYH1_k127_8161046_9 Peptidase M56 - - - 0.0000000000000008874 93.0
PYH1_k127_8188631_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1575.0
PYH1_k127_8188631_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 525.0
PYH1_k127_8188631_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 502.0
PYH1_k127_8188631_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 394.0
PYH1_k127_8188631_4 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000127 179.0
PYH1_k127_8188631_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000003927 108.0
PYH1_k127_8188631_6 Bacterial membrane protein, YfhO - - - 0.00005483 53.0
PYH1_k127_8188631_7 Type II secretion system (T2SS), protein G K02456 - - 0.0002175 52.0
PYH1_k127_8214864_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 4.898e-263 825.0
PYH1_k127_8214864_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 414.0
PYH1_k127_8214864_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
PYH1_k127_8214864_3 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 321.0
PYH1_k127_8214864_4 EamA-like transporter family - - - 0.00000000000000000000000000000003939 138.0
PYH1_k127_8214864_5 VanZ like family - - - 0.00004407 57.0
PYH1_k127_8217243_0 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1486.0
PYH1_k127_8217243_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 467.0
PYH1_k127_8217243_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 316.0
PYH1_k127_8272244_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 413.0
PYH1_k127_8272244_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009502 280.0
PYH1_k127_8272244_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000008293 249.0
PYH1_k127_8272244_3 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000002297 124.0
PYH1_k127_8272244_4 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.0000000000000000000001925 102.0
PYH1_k127_8272244_5 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000002128 102.0
PYH1_k127_8289125_0 NeuB family K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 335.0
PYH1_k127_8289125_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000003108 239.0
PYH1_k127_8289125_2 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000023 145.0
PYH1_k127_8289125_3 PFAM membrane protein of K08972 - - 0.000000000000000000000000001014 121.0
PYH1_k127_8289125_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000004137 99.0
PYH1_k127_8298874_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 445.0
PYH1_k127_8298874_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003302 281.0
PYH1_k127_8298874_2 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.000000000000001465 78.0
PYH1_k127_8314925_0 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 4.189e-243 792.0
PYH1_k127_8314925_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 411.0
PYH1_k127_8314925_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000224 306.0
PYH1_k127_8314925_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007107 241.0
PYH1_k127_8314925_5 Phosphatidylserine decarboxylase - - - 0.000000000000000000000000000000000000000002689 169.0
PYH1_k127_8314925_6 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.0000000000003138 81.0
PYH1_k127_8314925_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001533 65.0
PYH1_k127_8314925_8 - - - - 0.000001324 58.0
PYH1_k127_8337703_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 361.0
PYH1_k127_8337703_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
PYH1_k127_8337703_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 302.0
PYH1_k127_8337703_3 - - - - 0.0000000000000000000000000000000000000000000000001863 188.0
PYH1_k127_8337703_4 ABC transporter K02003 - - 0.000000000000000000000000000000000002784 141.0
PYH1_k127_8337703_5 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.000000000000000000008984 96.0
PYH1_k127_8337703_6 PIN domain - - - 0.0000000000000000008615 86.0
PYH1_k127_8337703_7 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.00000000000000206 79.0
PYH1_k127_8337703_8 - - - - 0.0000001152 61.0
PYH1_k127_8337703_9 Protein involved in meta-pathway of phenol degradation - - - 0.0001644 53.0
PYH1_k127_8338108_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 2151.0
PYH1_k127_8338108_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000282 147.0
PYH1_k127_8340479_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.388e-221 714.0
PYH1_k127_8340479_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 577.0
PYH1_k127_8340479_2 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000003881 134.0
PYH1_k127_8340479_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000007423 96.0
PYH1_k127_8340479_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000227 71.0
PYH1_k127_8359386_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.586e-295 929.0
PYH1_k127_8359386_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.353e-268 853.0
PYH1_k127_8359386_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000002051 220.0
PYH1_k127_8359386_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000009846 205.0
PYH1_k127_8359386_12 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000004247 185.0
PYH1_k127_8359386_13 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000899 188.0
PYH1_k127_8359386_14 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000007774 181.0
PYH1_k127_8359386_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000005543 136.0
PYH1_k127_8359386_16 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000006354 102.0
PYH1_k127_8359386_17 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000006303 70.0
PYH1_k127_8359386_19 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000008603 61.0
PYH1_k127_8359386_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 7.77e-216 702.0
PYH1_k127_8359386_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000001224 61.0
PYH1_k127_8359386_21 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0001063 47.0
PYH1_k127_8359386_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 445.0
PYH1_k127_8359386_4 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 448.0
PYH1_k127_8359386_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 411.0
PYH1_k127_8359386_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 381.0
PYH1_k127_8359386_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00375,K05825,K16422,K16423 - 1.1.3.46,2.6.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000002084 258.0
PYH1_k127_8359386_8 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000003652 231.0
PYH1_k127_8359386_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000004602 233.0
PYH1_k127_857317_0 reductase alpha subunit K00394 - 1.8.99.2 6.019e-275 853.0
PYH1_k127_857317_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 4.134e-232 741.0
PYH1_k127_857317_10 nitrate reductase activity - - - 0.000000000000000000000000000000005971 142.0
PYH1_k127_857317_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002417 134.0
PYH1_k127_857317_12 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000001807 124.0
PYH1_k127_857317_13 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000001542 106.0
PYH1_k127_857317_14 PFAM response regulator receiver - - - 0.0000000000000000000004486 111.0
PYH1_k127_857317_15 Ogr/Delta-like zinc finger - - - 0.000000000000000000002649 99.0
PYH1_k127_857317_16 transcriptional regulator - - - 0.00000000000000000009002 95.0
PYH1_k127_857317_17 PFAM response regulator receiver - - - 0.0000000000000001634 86.0
PYH1_k127_857317_18 PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding K01007 - 2.7.9.2 0.0000000000000005831 91.0
PYH1_k127_857317_19 PFAM response regulator receiver - - - 0.0000000000000006692 86.0
PYH1_k127_857317_2 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 597.0
PYH1_k127_857317_20 Conserved hypothetical protein 698 - - - 0.000002114 51.0
PYH1_k127_857317_3 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 429.0
PYH1_k127_857317_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
PYH1_k127_857317_5 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 400.0
PYH1_k127_857317_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
PYH1_k127_857317_7 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004675 260.0
PYH1_k127_857317_8 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000003416 250.0
PYH1_k127_857317_9 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000004163 229.0
PYH1_k127_870743_0 Beta-lactamase - - - 3.141e-216 690.0
PYH1_k127_870743_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 1.656e-214 678.0
PYH1_k127_870743_3 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000003391 103.0
PYH1_k127_870743_4 - - - - 0.00000000000002256 84.0
PYH1_k127_870743_5 Protein of unknown function DUF86 - - - 0.0005734 46.0
PYH1_k127_873453_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.784e-196 636.0
PYH1_k127_873453_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 547.0
PYH1_k127_873453_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 372.0
PYH1_k127_873453_4 PIN domain K19686 - - 0.000000000000000000000000000000000000000000000005194 176.0
PYH1_k127_873453_5 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000000000001882 129.0
PYH1_k127_873453_6 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000005764 130.0
PYH1_k127_873453_7 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000002402 119.0
PYH1_k127_873453_8 Tetratricopeptide repeat - - - 0.000488 51.0
PYH1_k127_958626_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1728.0
PYH1_k127_958626_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 559.0
PYH1_k127_958626_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 469.0
PYH1_k127_958626_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 421.0
PYH1_k127_958626_4 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 400.0
PYH1_k127_958626_5 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
PYH1_k127_958626_6 transcription factor binding K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000004938 221.0
PYH1_k127_958626_7 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000003911 239.0
PYH1_k127_958626_8 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000001213 196.0
PYH1_k127_958626_9 Gram-negative bacterial TonB protein C-terminal - - - 0.00006946 49.0
PYH1_k127_980171_0 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000131 138.0
PYH1_k127_980171_1 NmrA-like family - - - 0.000000000000000000000146 112.0
PYH1_k127_980171_2 oxidoreductase activity - - - 0.00000000006087 70.0
PYH1_k127_980171_3 Methyltransferase domain - - - 0.000000002154 70.0
PYH1_k127_980171_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000006748 65.0
PYH1_k127_980171_5 - - - - 0.0000002893 63.0