Overview

ID MAG03169
Name PYH1_bin.68
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Krumholzibacteriota
Class Krumholzibacteriia
Order WVZY01
Family WVZY01
Genus
Species
Assembly information
Completeness (%) 60.37
Contamination (%) 1.85
GC content (%) 62.0
N50 (bp) 3,051
Genome size (bp) 1,503,185

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1453

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1001361_0 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 407.0
PYH1_k127_1001361_1 Cytochrome c K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 390.0
PYH1_k127_1001361_2 oxidase subunit K08738 - - 0.0000002551 59.0
PYH1_k127_1011313_0 5'-nucleotidase - - - 0.0000000000000000000000248 107.0
PYH1_k127_1013216_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 343.0
PYH1_k127_1013216_1 PFAM DinB family - - - 0.000000000000000000000000000000000000000000000000001762 189.0
PYH1_k127_1013216_2 Cyclophilin-like K09143 - - 0.00000000000000000000000000000002863 133.0
PYH1_k127_1013460_0 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000005637 132.0
PYH1_k127_1013460_1 extracellular matrix structural constituent - - - 0.00000000000005434 82.0
PYH1_k127_1013460_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000003498 79.0
PYH1_k127_1019894_0 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 330.0
PYH1_k127_1019894_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000008122 233.0
PYH1_k127_1019894_2 Belongs to the MraZ family K03925 - - 0.000000002647 64.0
PYH1_k127_1025853_0 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 441.0
PYH1_k127_1025853_1 PFAM Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00005505 57.0
PYH1_k127_1059668_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000838 229.0
PYH1_k127_1059668_1 Bacterial Ig-like domain K07156 - - 0.0000000000000000000002043 109.0
PYH1_k127_1059668_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000008945 75.0
PYH1_k127_1059668_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000004087 75.0
PYH1_k127_1077209_0 aerobic electron transport chain K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 553.0
PYH1_k127_1077209_1 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 367.0
PYH1_k127_1080106_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1229.0
PYH1_k127_1087571_0 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 524.0
PYH1_k127_1087571_1 cellulose binding - - - 0.000000000004788 72.0
PYH1_k127_1092907_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 484.0
PYH1_k127_1092907_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003292 239.0
PYH1_k127_1092907_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000009208 157.0
PYH1_k127_110277_0 - - - - 0.000000000000003497 89.0
PYH1_k127_1114996_0 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 385.0
PYH1_k127_1114996_1 asparagine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 277.0
PYH1_k127_1114996_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000002708 239.0
PYH1_k127_113152_0 COG0471 Di- and tricarboxylate transporters K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 474.0
PYH1_k127_113152_1 - - - - 0.00000000000000000000005428 98.0
PYH1_k127_113152_2 Heavy-metal resistance - - - 0.0003502 49.0
PYH1_k127_1159797_0 response regulator K02481,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 492.0
PYH1_k127_1159797_1 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000002261 197.0
PYH1_k127_11823_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000003351 109.0
PYH1_k127_11823_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000115 82.0
PYH1_k127_1183519_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 447.0
PYH1_k127_1183519_1 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 295.0
PYH1_k127_1184786_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001283 278.0
PYH1_k127_1184786_1 PFAM lipopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000004993 178.0
PYH1_k127_1184786_2 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000000000000004417 158.0
PYH1_k127_1184786_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000001526 155.0
PYH1_k127_1184786_4 Histidine kinase - - - 0.00000000121 71.0
PYH1_k127_1184786_5 O-Antigen ligase - - - 0.00000002235 66.0
PYH1_k127_1184786_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000002301 61.0
PYH1_k127_1189045_0 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 312.0
PYH1_k127_1189045_1 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002205 245.0
PYH1_k127_1189045_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - - 0.000000000000000000000000002977 112.0
PYH1_k127_1189045_3 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000005883 78.0
PYH1_k127_1204402_0 fibronectin type III domain protein - - - 0.000000102 64.0
PYH1_k127_1204501_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 423.0
PYH1_k127_1288221_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 477.0
PYH1_k127_1288221_1 RecX family K03565 - - 0.0000001097 58.0
PYH1_k127_1288221_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000008926 51.0
PYH1_k127_1300357_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000002044 213.0
PYH1_k127_1300357_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000003776 132.0
PYH1_k127_1314054_0 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 524.0
PYH1_k127_1314054_1 Phospholipid methyltransferase - - - 0.000000000273 69.0
PYH1_k127_1332770_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000544 204.0
PYH1_k127_1332770_1 Sigma factor PP2C-like phosphatases K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000000000000000000000000000008414 165.0
PYH1_k127_1335803_0 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 357.0
PYH1_k127_1335803_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 317.0
PYH1_k127_1335803_2 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000116 160.0
PYH1_k127_1335803_3 PFAM glycoside hydrolase, family 13 domain protein - - - 0.0000000000000297 80.0
PYH1_k127_1340386_0 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.00000000000000000000000001804 113.0
PYH1_k127_1340386_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000907 112.0
PYH1_k127_1340386_2 TIGRFAM TonB family K03832 - - 0.0000111 57.0
PYH1_k127_1362263_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 316.0
PYH1_k127_1362263_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000002705 206.0
PYH1_k127_1389346_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 252.0
PYH1_k127_1389346_1 Polysaccharide biosynthesis protein - - - 0.000000000184 73.0
PYH1_k127_1392978_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
PYH1_k127_1392978_1 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000238 256.0
PYH1_k127_1392978_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000633 144.0
PYH1_k127_1392978_3 TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000009619 95.0
PYH1_k127_1393579_0 spore germination K07790 - - 0.0000000000000000000000000000000000000000000006611 178.0
PYH1_k127_1393579_1 - - - - 0.000000000000000000000000000000007683 147.0
PYH1_k127_1393579_2 oligosaccharyl transferase activity - - - 0.000000000000000000000001119 118.0
PYH1_k127_1393579_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000115 82.0
PYH1_k127_1412384_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 420.0
PYH1_k127_1412384_1 Belongs to the glycosyl hydrolase 18 family - - - 0.0000000000000000000000000000000000000000000000001532 186.0
PYH1_k127_1412384_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000009996 138.0
PYH1_k127_1421937_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 364.0
PYH1_k127_1421937_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 332.0
PYH1_k127_1439484_0 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 383.0
PYH1_k127_1439484_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
PYH1_k127_1439484_2 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000005824 161.0
PYH1_k127_1439484_3 cellulose binding K01179,K21449 - 3.2.1.4 0.00000000000000000000997 106.0
PYH1_k127_144042_0 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005997 250.0
PYH1_k127_144042_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000006141 195.0
PYH1_k127_144042_2 PadR family transcriptional regulator K10947 - - 0.0000000000000000000000000000000000008597 143.0
PYH1_k127_144042_3 - - - - 0.000000000000009663 84.0
PYH1_k127_144042_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000003502 68.0
PYH1_k127_1448916_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000001361 139.0
PYH1_k127_1448916_1 Histidine kinase - - - 0.0001078 54.0
PYH1_k127_1451824_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 350.0
PYH1_k127_1451824_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000008731 160.0
PYH1_k127_1451824_3 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.00000000000000000000000000000000000001446 161.0
PYH1_k127_1451824_4 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000003558 108.0
PYH1_k127_1451824_5 blue (type 1) copper K00368 - 1.7.2.1 0.000000003467 63.0
PYH1_k127_1460825_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 437.0
PYH1_k127_1460825_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000006398 156.0
PYH1_k127_1460825_2 reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000008247 149.0
PYH1_k127_1460825_3 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000002675 145.0
PYH1_k127_1463513_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 338.0
PYH1_k127_1463513_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 315.0
PYH1_k127_1463513_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001253 264.0
PYH1_k127_1463513_3 R3H domain protein K06346 - - 0.00000000000000000000000000000001144 146.0
PYH1_k127_1463513_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000001522 103.0
PYH1_k127_1473432_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.12e-308 955.0
PYH1_k127_1473432_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 1.102e-234 745.0
PYH1_k127_1473432_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 450.0
PYH1_k127_1473432_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
PYH1_k127_1473432_4 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
PYH1_k127_1473432_5 nickel cation binding K04651 - - 0.0000000000000000000000000001853 118.0
PYH1_k127_1473432_6 Hydrogenase maturation protease - - - 0.0000000000000000000007766 103.0
PYH1_k127_1473432_7 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000004449 60.0
PYH1_k127_1475235_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000001186 179.0
PYH1_k127_1475235_1 PD-(D/E)XK nuclease superfamily - - - 0.00000004317 66.0
PYH1_k127_1475623_0 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.0000000000000000000000000000000000001064 154.0
PYH1_k127_1475623_1 Belongs to the GbsR family - - - 0.00000000000000000000000008961 113.0
PYH1_k127_1505834_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458,K14660 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002049 271.0
PYH1_k127_1505834_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000005675 187.0
PYH1_k127_1510521_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000133 134.0
PYH1_k127_1543707_0 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000001409 191.0
PYH1_k127_1543707_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000004717 169.0
PYH1_k127_1543707_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000001001 136.0
PYH1_k127_1543707_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000002068 68.0
PYH1_k127_1550020_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 307.0
PYH1_k127_1554883_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 9.256e-236 737.0
PYH1_k127_1554883_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000006433 143.0
PYH1_k127_1554883_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000004556 127.0
PYH1_k127_1554883_3 PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000003925 78.0
PYH1_k127_1571371_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 390.0
PYH1_k127_1571371_1 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009836 260.0
PYH1_k127_1632289_0 von Willebrand factor type A domain - - - 0.000000000000000000002961 109.0
PYH1_k127_1689657_0 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 323.0
PYH1_k127_1689657_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000001081 152.0
PYH1_k127_1696477_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 383.0
PYH1_k127_1696477_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 367.0
PYH1_k127_171749_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 624.0
PYH1_k127_171749_1 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 520.0
PYH1_k127_171749_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002262 282.0
PYH1_k127_1724559_0 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 339.0
PYH1_k127_1724559_1 PFAM Signal transduction histidine kinase, internal region - - - 0.0000000002234 72.0
PYH1_k127_1724559_2 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.00000007661 55.0
PYH1_k127_1766688_0 inorganic phosphate transmembrane transporter activity K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 490.0
PYH1_k127_1766688_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 332.0
PYH1_k127_1788821_0 Tricorn protease C1 domain K08676 - - 0.0000000000000000000000000000000000000000005382 160.0
PYH1_k127_1788821_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000002269 113.0
PYH1_k127_1798915_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 244.0
PYH1_k127_1798915_1 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000449 209.0
PYH1_k127_1798915_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000669 206.0
PYH1_k127_1798915_3 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001813 166.0
PYH1_k127_1798915_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000007103 121.0
PYH1_k127_1798915_5 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000006809 69.0
PYH1_k127_1817233_0 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000003085 153.0
PYH1_k127_1817233_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000002025 136.0
PYH1_k127_1844624_0 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000000000000000000000000000000000000005593 175.0
PYH1_k127_1845268_0 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000008195 235.0
PYH1_k127_1845268_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000001372 198.0
PYH1_k127_1863307_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 310.0
PYH1_k127_1863307_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000001162 96.0
PYH1_k127_1863307_2 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000114 85.0
PYH1_k127_1863307_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000005491 74.0
PYH1_k127_1866329_0 Oligoendopeptidase f - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 402.0
PYH1_k127_1866329_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000002632 170.0
PYH1_k127_1866329_2 -acetyltransferase K00657 - 2.3.1.57 0.00000000000000000000000000000000000000002061 156.0
PYH1_k127_1871758_0 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 471.0
PYH1_k127_1871758_1 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 304.0
PYH1_k127_1871758_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 309.0
PYH1_k127_1871758_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007338 278.0
PYH1_k127_1871758_4 pfam abc K01990,K13926 - - 0.000000000000000000000000000000000000000000000002683 179.0
PYH1_k127_1871758_5 Transcriptional regulator - - - 0.000000000000000000000000000007955 121.0
PYH1_k127_1917715_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000003842 237.0
PYH1_k127_1917715_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000001133 183.0
PYH1_k127_1917715_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000001171 54.0
PYH1_k127_1927254_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000002534 103.0
PYH1_k127_1927254_1 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000002942 109.0
PYH1_k127_2038644_0 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000467 145.0
PYH1_k127_2038644_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00001286 48.0
PYH1_k127_2048489_0 Peptidase family C69 - - - 1.673e-252 790.0
PYH1_k127_2055673_0 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 333.0
PYH1_k127_2055673_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 293.0
PYH1_k127_2055673_2 RmlD substrate binding domain K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 286.0
PYH1_k127_2063073_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000004735 128.0
PYH1_k127_2063073_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000003639 95.0
PYH1_k127_2081422_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 1.008e-248 780.0
PYH1_k127_2089356_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000002226 80.0
PYH1_k127_2089356_1 Biopolymer transport protein K03559,K03560 - - 0.00000003508 60.0
PYH1_k127_2089356_2 Biopolymer transport protein K03559 - - 0.0000005735 60.0
PYH1_k127_2089356_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00002922 56.0
PYH1_k127_2089356_4 ompA family - - - 0.00008225 54.0
PYH1_k127_2104518_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 358.0
PYH1_k127_2104518_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 324.0
PYH1_k127_2104518_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000004561 61.0
PYH1_k127_2111841_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 581.0
PYH1_k127_2111841_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000001203 198.0
PYH1_k127_2111841_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0008714 46.0
PYH1_k127_2119727_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000434 281.0
PYH1_k127_2119727_1 - - - - 0.0000000000000000000000000000000000000000000005575 175.0
PYH1_k127_2124019_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 407.0
PYH1_k127_2124019_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000001367 124.0
PYH1_k127_2124019_2 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000001669 99.0
PYH1_k127_2129384_0 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
PYH1_k127_2129384_1 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000002265 223.0
PYH1_k127_2133824_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 366.0
PYH1_k127_2133824_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000005071 222.0
PYH1_k127_2149284_0 (ABC) transporter K15738,K18231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 577.0
PYH1_k127_2149284_1 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000001871 157.0
PYH1_k127_2152364_0 diguanylate cyclase - - - 0.00000001485 67.0
PYH1_k127_2160477_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 494.0
PYH1_k127_2160477_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
PYH1_k127_2187128_0 Pyruvate formate-lyase K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 339.0
PYH1_k127_2187128_1 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 336.0
PYH1_k127_2194703_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 482.0
PYH1_k127_2194703_1 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002182 290.0
PYH1_k127_2226361_0 Anti-sigma factor antagonist K02066,K04749 - - 0.00000000000000000005888 105.0
PYH1_k127_2226361_1 Anti-sigma factor antagonist K04749,K06378 - - 0.000000000000000001703 100.0
PYH1_k127_2248749_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003528 287.0
PYH1_k127_2248749_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000005701 175.0
PYH1_k127_2248749_2 Tetratricopeptide repeat - - - 0.000000000000367 83.0
PYH1_k127_2248749_3 PFAM ABC transporter K05833 - - 0.0000122 48.0
PYH1_k127_226742_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000001663 241.0
PYH1_k127_226742_1 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001137 246.0
PYH1_k127_226742_2 recA bacterial DNA recombination protein K03553 - - 0.000000000000000009566 87.0
PYH1_k127_2280017_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000113 161.0
PYH1_k127_2280017_1 Putative adhesin - - - 0.0000000006309 72.0
PYH1_k127_2280017_2 Anti-sigma-K factor rskA - - - 0.00003049 54.0
PYH1_k127_2280017_3 Polymer-forming cytoskeletal - - - 0.00009187 53.0
PYH1_k127_2305332_0 MreB/Mbl protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 474.0
PYH1_k127_2305332_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 291.0
PYH1_k127_2305332_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000003214 235.0
PYH1_k127_2305332_3 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.00000000000000000000000000000000009354 144.0
PYH1_k127_2305332_4 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000001454 135.0
PYH1_k127_2305332_5 rod shape-determining protein MreD K03571 - - 0.00000000000002373 82.0
PYH1_k127_230941_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 427.0
PYH1_k127_230941_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 355.0
PYH1_k127_230941_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 315.0
PYH1_k127_230941_3 PFAM Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 299.0
PYH1_k127_230941_4 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000006984 85.0
PYH1_k127_2314715_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 452.0
PYH1_k127_2314715_1 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000003106 187.0
PYH1_k127_2314715_2 - - - - 0.0000000000000000000000000000000004081 140.0
PYH1_k127_2317704_0 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
PYH1_k127_2317704_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000006597 121.0
PYH1_k127_2317704_2 oxidase subunit K08738 - - 0.00002838 53.0
PYH1_k127_2325945_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 325.0
PYH1_k127_2325945_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
PYH1_k127_2325945_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
PYH1_k127_2325945_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000001752 176.0
PYH1_k127_2325945_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000007185 124.0
PYH1_k127_2325945_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000009959 67.0
PYH1_k127_2368808_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 443.0
PYH1_k127_2368808_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000008266 88.0
PYH1_k127_2368808_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000007071 76.0
PYH1_k127_2370487_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006982 269.0
PYH1_k127_2370487_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000004308 195.0
PYH1_k127_2371756_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 290.0
PYH1_k127_2371756_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000003746 68.0
PYH1_k127_2382501_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.184e-247 773.0
PYH1_k127_2382501_1 Cupin domain - - - 0.00000000000000000000000000000001694 128.0
PYH1_k127_2382501_2 recA bacterial DNA recombination protein K03553 - - 0.00000000000000000000000002271 111.0
PYH1_k127_2399720_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 406.0
PYH1_k127_2399720_1 domain, Protein K01406,K03931,K15125 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000004369 237.0
PYH1_k127_2400319_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 484.0
PYH1_k127_2400319_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000005168 198.0
PYH1_k127_2419713_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 580.0
PYH1_k127_2419713_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 472.0
PYH1_k127_2419713_10 DoxX - - - 0.00002133 50.0
PYH1_k127_2419713_11 COG1225 Peroxiredoxin - - - 0.00008658 49.0
PYH1_k127_2419713_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 353.0
PYH1_k127_2419713_3 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 347.0
PYH1_k127_2419713_4 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000006061 198.0
PYH1_k127_2419713_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000001129 186.0
PYH1_k127_2419713_6 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.00000000000000000000000000000000004043 136.0
PYH1_k127_2419713_7 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.0000000000000000000002022 106.0
PYH1_k127_2419713_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000001541 78.0
PYH1_k127_2419713_9 FeS assembly protein SufD K09015 - - 0.0000001288 54.0
PYH1_k127_2425073_0 Peptidase family M49 K01277 - 3.4.14.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 391.0
PYH1_k127_2425073_1 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.0000000000000000000000000000000000000001827 158.0
PYH1_k127_2425073_2 Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family - - - 0.000000000000000000000002444 106.0
PYH1_k127_2473994_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 336.0
PYH1_k127_2473994_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000001428 218.0
PYH1_k127_2473994_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000007493 109.0
PYH1_k127_2474662_0 HEAT repeats K01387 - 3.4.24.3 0.00000000000000000006827 105.0
PYH1_k127_2474662_1 peptidyl-tyrosine sulfation - - - 0.000001079 60.0
PYH1_k127_2480090_0 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000005524 186.0
PYH1_k127_2480090_1 - - - - 0.000000000000000000107 95.0
PYH1_k127_2480090_2 DNA binding - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0097159,GO:1901363 - 0.000007203 59.0
PYH1_k127_2525121_0 - - - - 0.0000000000000000000000000000000000000000000000000000003836 203.0
PYH1_k127_2525121_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000004753 132.0
PYH1_k127_2525121_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000003656 120.0
PYH1_k127_2525121_3 Outer membrane protein beta-barrel domain - - - 0.0000000006216 70.0
PYH1_k127_2535969_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 329.0
PYH1_k127_2535969_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 306.0
PYH1_k127_2565362_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 586.0
PYH1_k127_2565362_1 Glycosyl transferases group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.000000000000000000000000000000000000000000000000000000000000000001571 235.0
PYH1_k127_2565362_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000004573 222.0
PYH1_k127_2589543_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 337.0
PYH1_k127_2589543_1 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001186 243.0
PYH1_k127_2589543_2 Tetratricopeptide repeat - - - 0.00004316 54.0
PYH1_k127_2606160_0 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 396.0
PYH1_k127_2606160_1 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000004018 160.0
PYH1_k127_2607446_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 286.0
PYH1_k127_2607446_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000001018 174.0
PYH1_k127_2607446_2 phosphorelay signal transduction system K02437 - - 0.0000000000003496 76.0
PYH1_k127_2678019_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 591.0
PYH1_k127_2678019_1 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001708 56.0
PYH1_k127_271273_0 energy transducer activity K03832 - - 0.0000000000001058 80.0
PYH1_k127_271273_1 biopolymer transport protein K03559 - - 0.000000000002389 73.0
PYH1_k127_271273_2 PFAM Outer membrane efflux protein - - - 0.0000000002791 71.0
PYH1_k127_2732990_0 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 362.0
PYH1_k127_2732990_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 322.0
PYH1_k127_2732990_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000003373 221.0
PYH1_k127_2732990_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000008372 173.0
PYH1_k127_2732990_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000006523 100.0
PYH1_k127_2771648_0 CoA-binding domain protein K09181 - - 0.0 1121.0
PYH1_k127_2771648_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 406.0
PYH1_k127_2771648_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 329.0
PYH1_k127_2771648_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000004646 160.0
PYH1_k127_2771648_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000001537 154.0
PYH1_k127_2771648_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000003149 67.0
PYH1_k127_2782706_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 337.0
PYH1_k127_2782706_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007002 276.0
PYH1_k127_2782706_2 - - - - 0.000000001226 64.0
PYH1_k127_2803351_0 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 418.0
PYH1_k127_2803351_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 390.0
PYH1_k127_2803351_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0001492 49.0
PYH1_k127_280649_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 4.55e-260 807.0
PYH1_k127_280649_1 fumarate reductase K00246 - - 0.000000000000000000000008394 104.0
PYH1_k127_2810729_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.051e-254 828.0
PYH1_k127_2810729_1 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.0000000000000000000000000001807 132.0
PYH1_k127_2810729_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000005025 117.0
PYH1_k127_2810729_3 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.000000006159 67.0
PYH1_k127_2827576_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 450.0
PYH1_k127_2827576_1 Branched-chain amino acid transport system / permease component K01997,K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 377.0
PYH1_k127_2827576_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001799 288.0
PYH1_k127_2827576_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000007509 190.0
PYH1_k127_2847422_0 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
PYH1_k127_2847422_1 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000002787 202.0
PYH1_k127_2847422_2 heme ABC exporter, ATP-binding protein CcmA K02193 - 3.6.3.41 0.0000000000000000000000000000000001585 137.0
PYH1_k127_2848788_0 Mut7-C ubiquitin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 313.0
PYH1_k127_2848788_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000001513 138.0
PYH1_k127_2848788_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000001192 107.0
PYH1_k127_2855921_0 DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000005357 231.0
PYH1_k127_2872295_0 Propeptide_C25 - - - 0.0000000000000000000000000000000000000000000000000000000001149 228.0
PYH1_k127_2887762_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 503.0
PYH1_k127_2887762_1 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 351.0
PYH1_k127_2887762_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 312.0
PYH1_k127_2887762_3 - - - - 0.00000000000000000000000000000000000000000001088 175.0
PYH1_k127_2887762_4 PFAM aldo keto reductase K07079 - - 0.00000000001651 66.0
PYH1_k127_2887762_5 Domain of unknown function (DUF4412) - - - 0.0000005474 60.0
PYH1_k127_2896174_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008053 255.0
PYH1_k127_2896174_1 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000002419 233.0
PYH1_k127_2896174_2 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000001006 130.0
PYH1_k127_2902237_0 auxin-activated signaling pathway K07088 - - 0.000000000000000000000000000000000000000000000000000006075 200.0
PYH1_k127_2902237_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000002749 167.0
PYH1_k127_2902237_2 Thioesterase superfamily - - - 0.000000000001636 70.0
PYH1_k127_2907309_0 Dienelactone hydrolase family - - - 2.026e-201 638.0
PYH1_k127_2907309_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000002756 160.0
PYH1_k127_2933596_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 379.0
PYH1_k127_2933596_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000000002845 179.0
PYH1_k127_2933596_2 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000003389 151.0
PYH1_k127_2933596_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000003014 139.0
PYH1_k127_2933596_4 AMP binding - - - 0.000000000000000000000000000002431 129.0
PYH1_k127_2933596_5 nuclear chromosome segregation - - - 0.000000000000000004718 90.0
PYH1_k127_2933596_6 Binding-protein-dependent transport system inner membrane component K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000001602 57.0
PYH1_k127_295082_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
PYH1_k127_295082_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 315.0
PYH1_k127_2957466_0 5'-nucleotidase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 413.0
PYH1_k127_2957466_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000005399 82.0
PYH1_k127_2957466_2 Transcriptional regulator - - - 0.00000000000003316 75.0
PYH1_k127_2961584_0 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000001003 207.0
PYH1_k127_2961584_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00002288 53.0
PYH1_k127_2966418_0 PA domain - - - 4.389e-212 672.0
PYH1_k127_2966418_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 360.0
PYH1_k127_2973927_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 266.0
PYH1_k127_2973927_1 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000005028 154.0
PYH1_k127_2977282_0 Belongs to the FtsK SpoIIIE SftA family K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 344.0
PYH1_k127_2977282_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000001973 179.0
PYH1_k127_2980548_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 342.0
PYH1_k127_2980548_1 Inner membrane component domain - - - 0.00000000000000000000000000000000000000000004768 168.0
PYH1_k127_2993126_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 353.0
PYH1_k127_2993126_1 - - - - 0.000006087 59.0
PYH1_k127_3003616_0 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008303 253.0
PYH1_k127_3003616_1 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000001261 249.0
PYH1_k127_3004514_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 307.0
PYH1_k127_3004514_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000008324 206.0
PYH1_k127_3004514_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000001683 212.0
PYH1_k127_3004514_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000005547 153.0
PYH1_k127_3004514_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000927 76.0
PYH1_k127_3004514_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000006265 65.0
PYH1_k127_3004514_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000002377 54.0
PYH1_k127_3004514_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0001011 44.0
PYH1_k127_301190_0 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 376.0
PYH1_k127_301190_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009521 263.0
PYH1_k127_301190_2 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000004 111.0
PYH1_k127_301190_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000002244 70.0
PYH1_k127_3013035_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004295 280.0
PYH1_k127_3013035_1 6,7-dimethyl-8-ribityllumazine synthase activity K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000003627 179.0
PYH1_k127_3013035_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000002549 119.0
PYH1_k127_3013035_3 PFAM Metallophosphoesterase - - - 0.00000000000000003571 89.0
PYH1_k127_3019496_0 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 473.0
PYH1_k127_3062815_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 486.0
PYH1_k127_3062815_1 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000278 100.0
PYH1_k127_3080114_0 endonuclease III K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
PYH1_k127_3080114_1 Acetyltransferase (GNAT) domain - - - 0.00000000002418 74.0
PYH1_k127_3080114_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00003749 51.0
PYH1_k127_3080114_3 Tetratricopeptide repeat - - - 0.0002876 48.0
PYH1_k127_3099706_0 citrate CoA-transferase activity K01643 - 2.8.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 535.0
PYH1_k127_3099706_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000009628 222.0
PYH1_k127_3099706_2 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000008855 140.0
PYH1_k127_3101212_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003309 256.0
PYH1_k127_3101212_1 membrane organization K07126,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000001923 244.0
PYH1_k127_3115705_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007811 255.0
PYH1_k127_3115705_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000588 236.0
PYH1_k127_3115705_2 Glycosyl transferases group 1 - - - 0.00000000000000000001656 96.0
PYH1_k127_3118218_0 Belongs to the glycosyl hydrolase 43 family K01181,K09955 - 3.2.1.8 0.00000000000000000000000000000008287 141.0
PYH1_k127_3118218_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.00000000000000000000000003178 124.0
PYH1_k127_3118218_2 transferase activity, transferring glycosyl groups - - - 0.00000002962 61.0
PYH1_k127_3121920_0 Adenylosuccinate synthetase K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 295.0
PYH1_k127_3121920_1 amine dehydrogenase activity - - - 0.00000000005339 74.0
PYH1_k127_3135888_0 Short chain dehydrogenase - - - 1.031e-199 643.0
PYH1_k127_3135888_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
PYH1_k127_3179253_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 351.0
PYH1_k127_3197686_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 326.0
PYH1_k127_3197686_1 protein kinase activity K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000002275 230.0
PYH1_k127_3199037_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 9.612e-242 760.0
PYH1_k127_3203439_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.341e-227 724.0
PYH1_k127_3203439_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 431.0
PYH1_k127_3203439_2 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 311.0
PYH1_k127_3203439_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002959 247.0
PYH1_k127_3203439_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000439 228.0
PYH1_k127_3203439_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000005902 173.0
PYH1_k127_3203439_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000005207 140.0
PYH1_k127_3203439_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000229 127.0
PYH1_k127_3203439_8 UbiA prenyltransferase family K03179,K04040 - 2.5.1.133,2.5.1.39,2.5.1.62 0.00000001519 64.0
PYH1_k127_3224778_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001381 265.0
PYH1_k127_3224778_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000008002 174.0
PYH1_k127_3224778_2 Acetyltransferase (GNAT) domain - - - 0.0003978 48.0
PYH1_k127_3235990_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 5.943e-197 625.0
PYH1_k127_3241700_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 590.0
PYH1_k127_3245523_0 4Fe-4S dicluster domain K00184 - - 2.142e-214 692.0
PYH1_k127_3245523_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000006214 120.0
PYH1_k127_3279614_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.295e-201 631.0
PYH1_k127_3279614_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 464.0
PYH1_k127_3279614_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001852 119.0
PYH1_k127_3279614_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000007634 107.0
PYH1_k127_3279614_12 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006243 95.0
PYH1_k127_3279614_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000003871 68.0
PYH1_k127_3279614_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000001133 63.0
PYH1_k127_3279614_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 396.0
PYH1_k127_3279614_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000561 284.0
PYH1_k127_3279614_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000002264 239.0
PYH1_k127_3279614_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000005009 222.0
PYH1_k127_3279614_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000003895 213.0
PYH1_k127_3279614_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002735 189.0
PYH1_k127_3279614_8 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000002569 143.0
PYH1_k127_3279614_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000547 138.0
PYH1_k127_3302550_0 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 493.0
PYH1_k127_3304189_0 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000002357 166.0
PYH1_k127_3304189_1 protein secretion K15125 - - 0.000000000000000000006257 108.0
PYH1_k127_3304189_2 Zinc metalloprotease (Elastase) K09607 - - 0.000007621 59.0
PYH1_k127_3304338_0 actin binding K12341 - - 0.000000000000000000000000000165 128.0
PYH1_k127_3313572_0 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 530.0
PYH1_k127_3313572_1 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001987 260.0
PYH1_k127_3313572_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000006167 233.0
PYH1_k127_3313572_3 Domain of unknown function (DUF378) K09779 - - 0.00000000000000006309 94.0
PYH1_k127_3313572_4 Outer membrane protein beta-barrel domain - - - 0.00003552 53.0
PYH1_k127_3353048_0 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 302.0
PYH1_k127_3353048_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000136 160.0
PYH1_k127_3353048_2 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000003873 156.0
PYH1_k127_336424_0 M6 family metalloprotease domain protein - - - 0.0000003135 63.0
PYH1_k127_336424_1 long-chain fatty acid transport protein - - - 0.00003093 54.0
PYH1_k127_3364832_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 423.0
PYH1_k127_3364832_1 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003813 272.0
PYH1_k127_3364832_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000003899 190.0
PYH1_k127_3364832_3 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000122 115.0
PYH1_k127_3391474_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 469.0
PYH1_k127_3391474_1 cystathionine gamma-synthase activity K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000006704 151.0
PYH1_k127_3391474_2 protein secretion K09800 - - 0.00001316 57.0
PYH1_k127_3409527_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 307.0
PYH1_k127_3409527_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
PYH1_k127_3409527_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000002459 178.0
PYH1_k127_3413733_0 dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 332.0
PYH1_k127_3413733_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
PYH1_k127_3413733_2 Psort location CytoplasmicMembrane, score K09153 - - 0.0000000000004774 75.0
PYH1_k127_3415559_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 337.0
PYH1_k127_3415559_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 266.0
PYH1_k127_3415559_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000006069 119.0
PYH1_k127_3415559_3 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000009002 121.0
PYH1_k127_3436827_0 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 425.0
PYH1_k127_3436827_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000001282 210.0
PYH1_k127_3449656_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 326.0
PYH1_k127_3449656_1 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000003978 212.0
PYH1_k127_3494783_0 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 266.0
PYH1_k127_3494783_1 Membrane protein involved in the export of o-antigen and teichoic acid - - - 0.00000000000000000000000000000000000000000004075 168.0
PYH1_k127_3502435_0 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001106 237.0
PYH1_k127_3513951_0 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 586.0
PYH1_k127_3545160_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000003803 90.0
PYH1_k127_3545160_1 response to copper ion K02388,K02396 - - 0.000000301 63.0
PYH1_k127_3545160_2 Bacterial Ig-like domain - - - 0.0004097 53.0
PYH1_k127_3628288_0 Cleaves the N-terminal amino acid of tripeptides K01258 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 298.0
PYH1_k127_3628288_1 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 294.0
PYH1_k127_3630232_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 314.0
PYH1_k127_3630232_1 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000000000001071 136.0
PYH1_k127_3642426_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 343.0
PYH1_k127_3642426_1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.000000000000000000000000000001515 129.0
PYH1_k127_3642426_2 Deoxynucleoside kinase - - - 0.00000000000000000000000008732 110.0
PYH1_k127_3642426_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000001075 100.0
PYH1_k127_3642426_4 WD40-like Beta Propeller Repeat - - - 0.0001724 51.0
PYH1_k127_3647522_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 7.954e-236 738.0
PYH1_k127_3667324_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001655 282.0
PYH1_k127_3667324_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001789 239.0
PYH1_k127_3667324_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000008365 195.0
PYH1_k127_3667324_3 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000001413 180.0
PYH1_k127_3667324_4 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000002186 183.0
PYH1_k127_3667324_5 Methyltransferase domain - - - 0.00000000000000000000000000000000002644 141.0
PYH1_k127_3667324_6 negative regulation of translational initiation K05554,K15885 - - 0.00000000000000000000000000000000318 134.0
PYH1_k127_3667324_7 - - - - 0.000000000000000000000004702 106.0
PYH1_k127_3672444_0 DNA-directed 5'-3' RNA polymerase activity K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 8.486e-251 782.0
PYH1_k127_367840_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 492.0
PYH1_k127_3691531_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000001053 244.0
PYH1_k127_3691531_1 Subtilase family - - - 0.00000000000000000000000000000000000000000002671 187.0
PYH1_k127_3691531_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000001268 99.0
PYH1_k127_3725888_0 inositol 2-dehydrogenase activity K13018 - 2.3.1.201 2.678e-228 721.0
PYH1_k127_3725888_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 516.0
PYH1_k127_3725888_2 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000008415 109.0
PYH1_k127_3746440_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 397.0
PYH1_k127_3758833_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009284 274.0
PYH1_k127_3758833_1 Histidine kinase K11357 - 2.7.13.3 0.00000000000000000000008199 112.0
PYH1_k127_3789776_0 Transposase and inactivated derivatives K00986,K07497 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 431.0
PYH1_k127_3789776_1 COG2963 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000005102 148.0
PYH1_k127_3789776_2 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000002993 151.0
PYH1_k127_3789776_3 Peptidase M56 - - - 0.000000000001784 81.0
PYH1_k127_3789776_4 PFAM transposase, mutator - - - 0.00000004521 61.0
PYH1_k127_3789776_5 cAMP biosynthetic process - - - 0.000002041 51.0
PYH1_k127_3797688_0 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002371 255.0
PYH1_k127_3797688_1 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000000001216 128.0
PYH1_k127_3797688_2 D-glucuronyl C5-epimerase C-terminus - - - 0.00000000002176 75.0
PYH1_k127_3797688_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000001216 50.0
PYH1_k127_3804329_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 448.0
PYH1_k127_3804329_1 - - - - 0.0000000145 61.0
PYH1_k127_3806113_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000007647 241.0
PYH1_k127_3806113_1 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000003786 122.0
PYH1_k127_3812660_0 Glycosyl hydrolase family 92 - - - 2.192e-213 676.0
PYH1_k127_3812660_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 378.0
PYH1_k127_3812660_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.0000000005468 67.0
PYH1_k127_3817529_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000005518 88.0
PYH1_k127_3817529_1 Tetratricopeptide repeat - - - 0.00074 51.0
PYH1_k127_3821210_0 cellulase activity K01081,K01179,K06931 - 3.1.3.5,3.2.1.4 0.00000000000000003193 95.0
PYH1_k127_38300_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 312.0
PYH1_k127_38300_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 309.0
PYH1_k127_38300_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002449 286.0
PYH1_k127_3835780_0 cystathionine gamma-synthase activity K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 361.0
PYH1_k127_3846482_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000002251 205.0
PYH1_k127_3846482_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000003129 79.0
PYH1_k127_3846482_2 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.000000001547 72.0
PYH1_k127_3848093_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000001374 236.0
PYH1_k127_3848093_1 Roadblock/LC7 domain - - - 0.0000000000000000000000000000282 119.0
PYH1_k127_3848093_2 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000000000000000006011 115.0
PYH1_k127_3848093_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0005807 50.0
PYH1_k127_387562_0 Amino acid permease - - - 4.475e-200 636.0
PYH1_k127_387562_1 Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000000001082 143.0
PYH1_k127_388271_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 3.349e-298 923.0
PYH1_k127_388271_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000006334 228.0
PYH1_k127_388271_2 Reductase C-terminal - - - 0.0000000000000000000000000005052 117.0
PYH1_k127_388271_3 - - - - 0.0000000000000002993 83.0
PYH1_k127_389709_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 346.0
PYH1_k127_389709_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000129 238.0
PYH1_k127_389709_2 Electron transfer flavoprotein K03522 - - 0.0004972 46.0
PYH1_k127_3898807_0 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001384 243.0
PYH1_k127_3898807_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000001811 131.0
PYH1_k127_3903938_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000166 149.0
PYH1_k127_3916631_0 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 421.0
PYH1_k127_3916631_1 - - - - 0.00000000000000000000000000000006453 129.0
PYH1_k127_3916631_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000002167 68.0
PYH1_k127_3920847_0 Uncharacterized protein family (UPF0051) K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 437.0
PYH1_k127_3920847_1 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 416.0
PYH1_k127_3920847_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
PYH1_k127_3920847_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000002157 54.0
PYH1_k127_3931423_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 473.0
PYH1_k127_3931423_1 Glycosyl transferases group 1 - - - 0.00000000000000000008412 104.0
PYH1_k127_3933455_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000008517 177.0
PYH1_k127_3933455_1 cellulose binding K12132 - 2.7.11.1 0.000000000000000000000000322 119.0
PYH1_k127_3933455_2 peptidyl-tyrosine sulfation - - - 0.000000000004861 79.0
PYH1_k127_3933455_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000002762 63.0
PYH1_k127_3937959_0 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000004937 231.0
PYH1_k127_3937959_1 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000001566 182.0
PYH1_k127_3942483_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002065 279.0
PYH1_k127_3942483_1 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000008043 190.0
PYH1_k127_3942483_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00006729 48.0
PYH1_k127_3954669_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 491.0
PYH1_k127_3990826_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002397 243.0
PYH1_k127_3990826_1 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.000000000000000000000000000000000000000000000000000000001474 223.0
PYH1_k127_3990826_2 Tetratricopeptide repeat - - - 0.000000001377 66.0
PYH1_k127_3994698_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 522.0
PYH1_k127_3994698_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000031 181.0
PYH1_k127_3994698_2 SpoVG K06412 - - 0.000000000000000000000001741 105.0
PYH1_k127_3994698_3 PFAM UbiA prenyltransferase - - - 0.000009353 48.0
PYH1_k127_3997928_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
PYH1_k127_3997928_1 PFAM OmpA MotB domain protein K03286 - - 0.0000000000000000000000000000000000000000000000000000000008646 208.0
PYH1_k127_3997928_2 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000005095 203.0
PYH1_k127_4041824_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 430.0
PYH1_k127_4041824_1 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 307.0
PYH1_k127_4041824_2 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000000002635 109.0
PYH1_k127_4064988_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 570.0
PYH1_k127_4084063_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 349.0
PYH1_k127_4084063_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 326.0
PYH1_k127_4084063_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
PYH1_k127_4084063_3 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000106 142.0
PYH1_k127_4084063_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000005257 129.0
PYH1_k127_4084063_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.000000000000000000000000000001967 123.0
PYH1_k127_4085910_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000005395 208.0
PYH1_k127_4085910_1 PFAM PEGA domain - - - 0.000000000000000000001898 105.0
PYH1_k127_4090427_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 539.0
PYH1_k127_4104382_0 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000386 153.0
PYH1_k127_4104382_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000071 93.0
PYH1_k127_4104382_2 cellulase activity - - - 0.0000000000000009606 89.0
PYH1_k127_4118797_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000002245 126.0
PYH1_k127_4118797_1 DsrE/DsrF/DrsH-like family - - - 0.0000002563 53.0
PYH1_k127_4118797_2 - - - - 0.00000293 53.0
PYH1_k127_4123102_0 Multidrug efflux transporter, MFS family protein - - - 0.0000000003198 72.0
PYH1_k127_4123261_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003043 245.0
PYH1_k127_4123261_1 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000001166 171.0
PYH1_k127_4123261_2 - - - - 0.00003299 53.0
PYH1_k127_4147315_0 ABC transporter K01996,K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 328.0
PYH1_k127_4147315_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000001545 130.0
PYH1_k127_4147315_2 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000001625 103.0
PYH1_k127_4147315_3 Protein tyrosine kinase - - - 0.000004197 58.0
PYH1_k127_4150294_0 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 350.0
PYH1_k127_4150294_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000003548 217.0
PYH1_k127_4150294_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000003104 95.0
PYH1_k127_4160211_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000001821 192.0
PYH1_k127_4160211_1 peptidyl-tyrosine sulfation - - - 0.0000000000002775 80.0
PYH1_k127_4176111_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 9.717e-236 746.0
PYH1_k127_4176111_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 266.0
PYH1_k127_4176111_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000001522 235.0
PYH1_k127_4176111_3 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000007595 154.0
PYH1_k127_4177015_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000008051 185.0
PYH1_k127_4177015_1 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000001168 120.0
PYH1_k127_4190071_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 464.0
PYH1_k127_4190071_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 398.0
PYH1_k127_4190071_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000001581 111.0
PYH1_k127_4190071_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000004409 94.0
PYH1_k127_4190071_4 Belongs to the complex I 75 kDa subunit family K03934 - 1.6.5.3,1.6.99.3 0.0000000005274 63.0
PYH1_k127_419500_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000002456 160.0
PYH1_k127_419500_1 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000000000003198 149.0
PYH1_k127_419500_2 Endonuclease I - - - 0.000003836 57.0
PYH1_k127_4199622_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000205 189.0
PYH1_k127_4199622_1 Peptidase M50 - - - 0.000000000000000000000000000000000000000000001994 173.0
PYH1_k127_4199622_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000004107 168.0
PYH1_k127_4199622_3 Domain of unknown function (DUF366) K09139 - - 0.00000000000000000000000000000005824 133.0
PYH1_k127_4199622_4 Fibronectin type 3 domain - - - 0.0000001552 59.0
PYH1_k127_4203550_0 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 468.0
PYH1_k127_4203550_1 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 422.0
PYH1_k127_4203550_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000724 102.0
PYH1_k127_4212730_0 DNA polymerase K02337,K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1201.0
PYH1_k127_4212730_1 domain protein K13735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 341.0
PYH1_k127_4212730_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000062 93.0
PYH1_k127_4212730_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0003605 54.0
PYH1_k127_4227840_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 1.803e-287 898.0
PYH1_k127_4227840_1 NTPase - - - 0.0000000000000000000000000000000000000000000000000208 185.0
PYH1_k127_4227840_2 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000349 156.0
PYH1_k127_4227840_3 Protein of unknown function (DUF2809) - - - 0.000000000000000000000000000000003836 138.0
PYH1_k127_4229418_0 tail specific protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 340.0
PYH1_k127_4229418_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
PYH1_k127_4229418_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001019 196.0
PYH1_k127_4242334_0 Peptidase M56 - - - 0.00000000000000000000000000000000002753 150.0
PYH1_k127_4242334_1 MacB-like periplasmic core domain K02004 - - 0.00000000000001863 74.0
PYH1_k127_4242334_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000001519 74.0
PYH1_k127_4242746_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 527.0
PYH1_k127_4242746_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000001052 109.0
PYH1_k127_4251876_0 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000004946 185.0
PYH1_k127_4251876_1 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000003816 119.0
PYH1_k127_4252675_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 359.0
PYH1_k127_4252675_1 - - - - 0.0000000000000906 76.0
PYH1_k127_4252675_2 - - - - 0.0000000000002 76.0
PYH1_k127_4262912_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006814 284.0
PYH1_k127_4262912_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000001342 143.0
PYH1_k127_4262912_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000003351 92.0
PYH1_k127_4262912_3 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.0000000000005114 78.0
PYH1_k127_4262912_4 membrane - - - 0.000003493 59.0
PYH1_k127_4268493_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 305.0
PYH1_k127_4268493_1 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000124 237.0
PYH1_k127_4268493_2 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000002182 142.0
PYH1_k127_4268493_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000001161 87.0
PYH1_k127_427024_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 366.0
PYH1_k127_427024_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000009963 221.0
PYH1_k127_427024_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0002559 46.0
PYH1_k127_4276096_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 460.0
PYH1_k127_4276096_1 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 416.0
PYH1_k127_4276096_2 isobutyryl-CoA mutase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007555 274.0
PYH1_k127_4276096_3 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000002452 188.0
PYH1_k127_4276096_4 Esterase-like activity of phytase - - - 0.00000003963 62.0
PYH1_k127_4308169_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.175e-219 696.0
PYH1_k127_4308169_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 317.0
PYH1_k127_4308169_2 ATP-NAD kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000006808 199.0
PYH1_k127_4310057_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.701e-272 852.0
PYH1_k127_4319022_0 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 364.0
PYH1_k127_4319022_1 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000008978 184.0
PYH1_k127_4319022_2 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000004142 184.0
PYH1_k127_4319022_3 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000004084 160.0
PYH1_k127_4319022_4 - - - - 0.00000000000000000001554 95.0
PYH1_k127_4319022_5 Belongs to the BshC family K22136 - - 0.000000003096 67.0
PYH1_k127_432078_0 Protein of unknown function (DUF2723) K16928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 399.0
PYH1_k127_432078_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000359 289.0
PYH1_k127_432078_2 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027 - - 0.0000000000000000000000000003515 132.0
PYH1_k127_432078_3 NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.000000001509 59.0
PYH1_k127_4338863_0 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000000104 207.0
PYH1_k127_4338863_1 Patatin-like phospholipase K06900 - - 0.0000000000000000000000000003411 127.0
PYH1_k127_4338863_2 Peptidase, S9A B C family, catalytic domain protein - - - 0.0000000000000000000000001161 115.0
PYH1_k127_4338863_3 Thioredoxin - - - 0.000000000000000000004189 102.0
PYH1_k127_4398608_0 Calx-beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 467.0
PYH1_k127_4398608_1 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 437.0
PYH1_k127_4407258_0 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 329.0
PYH1_k127_4407258_1 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000003164 196.0
PYH1_k127_4409423_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 436.0
PYH1_k127_4409423_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000002183 178.0
PYH1_k127_4409423_2 Polysaccharide biosynthesis/export protein - - - 0.000004704 52.0
PYH1_k127_4444394_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 413.0
PYH1_k127_4444394_1 protein secretion K09800 - - 0.0000000000000000000004437 100.0
PYH1_k127_4471756_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004737 277.0
PYH1_k127_4478801_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001831 282.0
PYH1_k127_4487049_0 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000000000000000000000000000000000000000000000000003904 212.0
PYH1_k127_4492769_0 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.000000000000000000000000000000000000006741 160.0
PYH1_k127_4492769_1 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000007505 119.0
PYH1_k127_4492769_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.00000000000000000000001129 102.0
PYH1_k127_4517295_0 PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 375.0
PYH1_k127_4517295_1 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007434 265.0
PYH1_k127_4521585_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000003073 209.0
PYH1_k127_4532180_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004709 239.0
PYH1_k127_4532180_1 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000008774 198.0
PYH1_k127_4532180_2 Cytochrome b subunit of the bc K00412,K02635 - - 0.000000000000000000000000000000000001906 147.0
PYH1_k127_4554262_0 Protein of unknown function (DUF354) K09726 - - 0.000000000004183 69.0
PYH1_k127_4554262_1 D-glucuronyl C5-epimerase C-terminus - - - 0.000000008155 67.0
PYH1_k127_4554262_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000008629 56.0
PYH1_k127_4558011_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 1.617e-272 850.0
PYH1_k127_4558011_1 glutamine synthetase K01915 - 6.3.1.2 1.435e-200 637.0
PYH1_k127_4558011_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 475.0
PYH1_k127_4558011_3 Smr domain - - - 0.000000000000000000000000000002257 123.0
PYH1_k127_4584632_0 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000006541 142.0
PYH1_k127_4584632_1 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000888 70.0
PYH1_k127_4584632_2 TadE-like protein - - - 0.0000000114 63.0
PYH1_k127_4584632_3 Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000001823 63.0
PYH1_k127_4584632_4 Belongs to the GSP D family K02280 - - 0.0000002376 61.0
PYH1_k127_4593304_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000003253 206.0
PYH1_k127_4593304_1 Propeptide_C25 - - - 0.000000000000000000000007884 108.0
PYH1_k127_4593304_2 - - - - 0.00000005173 65.0
PYH1_k127_4603382_0 A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
PYH1_k127_4603382_1 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000002975 190.0
PYH1_k127_4607931_0 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000002562 225.0
PYH1_k127_4607931_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02282 - - 0.000000000000000000000000000000000000000000000006696 184.0
PYH1_k127_4607931_2 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000002358 126.0
PYH1_k127_4614103_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 556.0
PYH1_k127_4614103_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000005101 209.0
PYH1_k127_4638764_0 extracellular matrix structural constituent - - - 0.00000000000001745 81.0
PYH1_k127_4649344_0 saccharopine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 471.0
PYH1_k127_4649344_1 serine acetyltransferase K00640 - 2.3.1.30 0.00000000001892 65.0
PYH1_k127_4649344_2 YceI-like domain - - - 0.00000000002385 64.0
PYH1_k127_4658402_0 nuclease activity - - - 0.00000000000000000000000000000000000003746 150.0
PYH1_k127_4658402_1 cellulase activity K01201 - 3.2.1.45 0.0000000000000000004812 100.0
PYH1_k127_4658402_2 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000227 85.0
PYH1_k127_4658972_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 560.0
PYH1_k127_4658972_1 - - - - 0.0000355 51.0
PYH1_k127_4666008_0 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 418.0
PYH1_k127_4666008_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000002089 71.0
PYH1_k127_4682333_0 TrkA-N domain - - - 0.000000000000000000000000000000000000000000000000001173 201.0
PYH1_k127_4682333_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000001489 160.0
PYH1_k127_4696363_0 Tetratricopeptide repeat - - - 0.0000003067 63.0
PYH1_k127_4696948_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 543.0
PYH1_k127_4696948_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 372.0
PYH1_k127_4696948_2 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000544 274.0
PYH1_k127_4696948_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000003456 214.0
PYH1_k127_4696948_4 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.000006732 54.0
PYH1_k127_4697705_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 316.0
PYH1_k127_4697705_1 Psort location CytoplasmicMembrane, score K01992 - - 0.0000000000000000000000000000000000000000000000000001135 201.0
PYH1_k127_4700006_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 550.0
PYH1_k127_4700006_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000001284 230.0
PYH1_k127_4700006_2 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000005538 143.0
PYH1_k127_4700006_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000004061 121.0
PYH1_k127_4700006_4 Exodeoxyribonuclease V, gamma subunit K03657 - 3.6.4.12 0.000000000000000000001488 95.0
PYH1_k127_4710273_0 Creatinine amidohydrolase K01470 - 3.5.2.10 7.872e-220 695.0
PYH1_k127_4720903_0 - K01992 - - 2.36e-211 671.0
PYH1_k127_4720903_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
PYH1_k127_472371_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 480.0
PYH1_k127_472371_1 S-acyltransferase activity K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 351.0
PYH1_k127_472371_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000006807 232.0
PYH1_k127_4746272_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 534.0
PYH1_k127_4746272_1 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008614 282.0
PYH1_k127_4746272_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000001015 213.0
PYH1_k127_4746272_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000002995 76.0
PYH1_k127_4747006_0 regulation of RNA biosynthetic process K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000006972 173.0
PYH1_k127_4747006_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000104 114.0
PYH1_k127_4747006_2 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000003735 52.0
PYH1_k127_4775467_0 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 483.0
PYH1_k127_4775467_1 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 434.0
PYH1_k127_4775467_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 342.0
PYH1_k127_4779339_0 Glycosyltransferase like family 2 K03606,K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008116 261.0
PYH1_k127_4779339_1 Two component regulator propeller - - - 0.000000000000000000004099 109.0
PYH1_k127_4809663_0 pfam nudix - - - 0.00000000000000000000000000001231 122.0
PYH1_k127_4809663_1 Salt-induced outer membrane protein K07283 - - 0.0000002749 62.0
PYH1_k127_4815177_0 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000000007672 226.0
PYH1_k127_4819772_0 Tetratricopeptide repeat - - - 0.00000000000000000000003067 112.0
PYH1_k127_4819772_1 Capsule assembly protein Wzi - - - 0.00000000000008915 84.0
PYH1_k127_4833037_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 2.446e-194 620.0
PYH1_k127_4833037_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000001594 223.0
PYH1_k127_4847676_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000001388 153.0
PYH1_k127_4850735_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009921 254.0
PYH1_k127_485435_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.914e-286 891.0
PYH1_k127_485435_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 463.0
PYH1_k127_485435_2 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
PYH1_k127_485435_3 - - - - 0.00000000000000000000000005023 124.0
PYH1_k127_485435_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000008177 108.0
PYH1_k127_4891171_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 345.0
PYH1_k127_4891171_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000005558 189.0
PYH1_k127_4897846_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 402.0
PYH1_k127_4897846_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.000000000000000000000000000000000001592 143.0
PYH1_k127_4903214_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001053 278.0
PYH1_k127_4903214_1 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000004002 193.0
PYH1_k127_4903214_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000002204 124.0
PYH1_k127_4903214_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K12982 - - 0.00000000000000006158 86.0
PYH1_k127_4913427_0 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.000000000000000000000000000000000001285 143.0
PYH1_k127_4913427_1 lipopolysaccharide biosynthesis protein - - - 0.0000000007489 71.0
PYH1_k127_4913427_2 polysaccharide K01991,K20987 - - 0.00007765 49.0
PYH1_k127_4925634_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000001557 155.0
PYH1_k127_4925634_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000002231 124.0
PYH1_k127_4925634_2 Radical SAM domain protein - - - 0.00000000000000000000000000007546 127.0
PYH1_k127_4925634_3 Belongs to the SUA5 family - - - 0.0000000000000000006169 96.0
PYH1_k127_4926811_0 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 374.0
PYH1_k127_4926811_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000005535 156.0
PYH1_k127_4926811_2 Tetratricopeptide repeat - - - 0.0000931 46.0
PYH1_k127_4927005_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000155 240.0
PYH1_k127_4927005_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000008954 132.0
PYH1_k127_4927005_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000002254 124.0
PYH1_k127_4929053_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 328.0
PYH1_k127_4929053_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
PYH1_k127_4929053_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000009006 181.0
PYH1_k127_4929053_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000002959 168.0
PYH1_k127_4930289_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 313.0
PYH1_k127_4930289_1 Nitrogen-fixing NifU domain protein - - - 0.00000000000000000001063 93.0
PYH1_k127_4930289_2 Sigma factor PP2C-like phosphatases - - - 0.00000000000004756 81.0
PYH1_k127_4948452_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 507.0
PYH1_k127_4948452_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001561 222.0
PYH1_k127_4948452_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000007444 134.0
PYH1_k127_4948452_3 Outer membrane protein beta-barrel domain - - - 0.000000002282 66.0
PYH1_k127_4951137_0 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 517.0
PYH1_k127_4951137_1 Cupin superfamily (DUF985) - - - 0.000000000000000000000000000000000000000000000000000000000002111 212.0
PYH1_k127_4951137_2 Tellurite resistance protein TehB - - - 0.000000000000000000000000007609 113.0
PYH1_k127_4951137_3 Protein of unknown function (DUF2892) - - - 0.000000000000000001499 89.0
PYH1_k127_4959387_0 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 319.0
PYH1_k127_4959387_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
PYH1_k127_4959387_2 Periplasmic Protein - - - 0.0000000004588 66.0
PYH1_k127_4962017_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 606.0
PYH1_k127_4963361_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 588.0
PYH1_k127_4963361_1 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000008406 108.0
PYH1_k127_4963361_2 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000001043 85.0
PYH1_k127_4963361_3 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes K14194 - - 0.00007871 53.0
PYH1_k127_4964156_0 Peptidase, M23 family - - - 0.00000000000000000000000000000000000001849 154.0
PYH1_k127_4964156_1 Belongs to the ParB family K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.000000000000000000000005426 106.0
PYH1_k127_4964156_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000001173 101.0
PYH1_k127_4977431_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000002108 214.0
PYH1_k127_4977431_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000001148 124.0
PYH1_k127_4982358_0 PFAM Tetratricopeptide - - - 0.00000000000009076 84.0
PYH1_k127_4982358_1 long-chain fatty acid transporting porin activity - - - 0.0000000003249 69.0
PYH1_k127_4994609_0 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 496.0
PYH1_k127_4994609_1 PFAM ABC transporter related K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 285.0
PYH1_k127_5043090_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.24e-315 987.0
PYH1_k127_5043090_1 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000000000000000000000000000000000000000000000003317 204.0
PYH1_k127_505418_0 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000009162 211.0
PYH1_k127_505418_1 Hydrolase K21471 - - 0.0000000000000000000000000000009574 124.0
PYH1_k127_5057128_0 YceI-like domain - - - 0.000000000000000000000000000000000000000000000005161 176.0
PYH1_k127_5057128_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001157 173.0
PYH1_k127_5061107_0 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000002754 148.0
PYH1_k127_5061107_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000003041 64.0
PYH1_k127_5109915_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 514.0
PYH1_k127_5109915_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 394.0
PYH1_k127_5109915_2 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000004183 163.0
PYH1_k127_5109915_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000006285 93.0
PYH1_k127_5109915_4 denitrification pathway - - - 0.00000000000001092 77.0
PYH1_k127_5112347_0 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008007 274.0
PYH1_k127_5112347_1 PhoU domain K02039 - - 0.000000000000000003764 85.0
PYH1_k127_5114493_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 467.0
PYH1_k127_5114493_1 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000003228 237.0
PYH1_k127_5114493_2 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000001959 239.0
PYH1_k127_5114493_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000003625 166.0
PYH1_k127_5126392_0 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 362.0
PYH1_k127_5126392_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 279.0
PYH1_k127_5126392_2 Rieske 2Fe-2S iron-sulphur domain K05710,K14750 - - 0.000000000000000000000003755 104.0
PYH1_k127_5148966_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 412.0
PYH1_k127_5159905_0 Flavin containing amine oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 4.871e-207 655.0
PYH1_k127_5159905_1 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000002693 191.0
PYH1_k127_5159905_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000004756 66.0
PYH1_k127_5251354_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 5.06e-203 641.0
PYH1_k127_5251354_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000009433 157.0
PYH1_k127_5251354_2 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000001707 111.0
PYH1_k127_5251354_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01142 - 3.1.11.2 0.0000000000000005916 83.0
PYH1_k127_5251354_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000001407 53.0
PYH1_k127_5284194_0 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 551.0
PYH1_k127_5284194_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000008221 93.0
PYH1_k127_5295985_0 PFAM Carbamoyltransferase K00612 - - 1.418e-238 746.0
PYH1_k127_5295985_1 - - - - 0.00000000000000000000000000000007082 130.0
PYH1_k127_5295985_2 - - - - 0.000000000000000002151 86.0
PYH1_k127_5319418_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 306.0
PYH1_k127_5319418_1 domain, Protein K01406,K03931,K15125 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000005986 209.0
PYH1_k127_5319418_2 cellulose binding K00505 - 1.14.18.1 0.000000000004788 79.0
PYH1_k127_5319418_3 COG1082 Sugar phosphate isomerases epimerases - - - 0.00002707 55.0
PYH1_k127_5334934_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 395.0
PYH1_k127_5334934_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000003843 94.0
PYH1_k127_5341779_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000003968 242.0
PYH1_k127_5341779_1 HD domain - - - 0.00000000000000000000000000000000836 130.0
PYH1_k127_5348874_0 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000002863 149.0
PYH1_k127_5348874_1 Redoxin K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000001434 123.0
PYH1_k127_5348874_2 Redoxin K03564 - 1.11.1.15 0.0000000000009776 70.0
PYH1_k127_5348874_3 metal-dependent phosphoesterase, PHP family K07053 - 3.1.3.97 0.00000000001794 66.0
PYH1_k127_5348874_4 Belongs to the sulfur carrier protein TusA family - - - 0.0008692 46.0
PYH1_k127_5353294_0 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000004826 248.0
PYH1_k127_5354728_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 443.0
PYH1_k127_5354728_1 META domain - - - 0.0000000000000000000000000000000000000000000001169 180.0
PYH1_k127_5355844_0 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000004114 178.0
PYH1_k127_5355844_1 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.000000000000000000000000000000000009511 143.0
PYH1_k127_5355844_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000004994 89.0
PYH1_k127_5367724_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 576.0
PYH1_k127_5367724_1 Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family - - - 0.000000000000000000000000000000001148 131.0
PYH1_k127_5367724_3 TIR domain - - - 0.000000002597 70.0
PYH1_k127_539153_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008801 266.0
PYH1_k127_539153_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000006877 178.0
PYH1_k127_5406482_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.006e-260 814.0
PYH1_k127_5406482_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
PYH1_k127_5416810_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000000000523 96.0
PYH1_k127_5416810_1 protein kinase activity - - - 0.00000001276 69.0
PYH1_k127_5416810_2 type IV pilus modification protein PilV K02458,K02671 - - 0.00001619 56.0
PYH1_k127_5416810_3 Pilus assembly protein PilX K02673 - - 0.0001171 48.0
PYH1_k127_5416810_4 general secretion pathway protein K02456,K02457,K10930 - - 0.0004929 49.0
PYH1_k127_5418974_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 619.0
PYH1_k127_5418974_1 PFAM RNA recognition motif - - - 0.000000000000000000000000105 109.0
PYH1_k127_5418974_2 Peptidase m28 - - - 0.000000000000000000000001949 108.0
PYH1_k127_5419255_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 2.403e-278 876.0
PYH1_k127_5422125_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 459.0
PYH1_k127_5422125_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000009043 227.0
PYH1_k127_5422125_2 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000002591 107.0
PYH1_k127_5450476_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1109.0
PYH1_k127_5450476_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000114 194.0
PYH1_k127_5450476_2 membrane K08972 - - 0.0001198 51.0
PYH1_k127_5471968_0 Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000000000000000000000000001257 211.0
PYH1_k127_5471968_1 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.000000000000000000000000000000000000000002459 164.0
PYH1_k127_5471968_2 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000474 154.0
PYH1_k127_5480235_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 4.121e-299 930.0
PYH1_k127_5480235_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
PYH1_k127_5480235_2 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000003474 73.0
PYH1_k127_5500657_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 568.0
PYH1_k127_5500657_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 421.0
PYH1_k127_5513807_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 507.0
PYH1_k127_5517096_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
PYH1_k127_5517096_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000002561 114.0
PYH1_k127_5517096_2 Putative zinc-finger - - - 0.00001876 55.0
PYH1_k127_5525693_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 601.0
PYH1_k127_5560765_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 306.0
PYH1_k127_5560765_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000002137 199.0
PYH1_k127_5560765_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000008255 202.0
PYH1_k127_5560765_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000009033 123.0
PYH1_k127_5562103_0 Zn_pept - - - 2.698e-195 630.0
PYH1_k127_5562103_1 - - - - 0.000003876 52.0
PYH1_k127_5564805_0 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 313.0
PYH1_k127_5564805_1 Biotin-lipoyl like K02005 - - 0.0000000000000001897 87.0
PYH1_k127_5564805_2 Outer membrane efflux protein - - - 0.00000000004187 68.0
PYH1_k127_5567136_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000007493 222.0
PYH1_k127_5567136_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000002505 92.0
PYH1_k127_5575120_0 Sigma factor PP2C-like phosphatases K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000000000000000000000000000000000008926 184.0
PYH1_k127_5575120_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000007269 163.0
PYH1_k127_5575120_2 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 0.00005207 56.0
PYH1_k127_5590162_0 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000535 88.0
PYH1_k127_5590162_1 Cold shock K03704 - - 0.00000000000007268 72.0
PYH1_k127_5605790_0 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000000000000000000000004216 122.0
PYH1_k127_5605790_1 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000005428 98.0
PYH1_k127_5615444_0 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 576.0
PYH1_k127_5615444_1 - - - - 0.0001407 48.0
PYH1_k127_5626195_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 544.0
PYH1_k127_5626195_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000002324 139.0
PYH1_k127_5626195_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000121 79.0
PYH1_k127_5653044_0 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 318.0
PYH1_k127_5653044_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000001143 236.0
PYH1_k127_5653044_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000776 96.0
PYH1_k127_5653044_3 - - - - 0.000004589 56.0
PYH1_k127_5654160_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000002632 178.0
PYH1_k127_5675673_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 529.0
PYH1_k127_5675673_1 COG1122 ABC-type cobalt transport system, ATPase component K16786,K16787 - - 0.00000000000000000000000000000000000000000003803 177.0
PYH1_k127_5690837_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.178e-229 724.0
PYH1_k127_5758814_0 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 336.0
PYH1_k127_5758814_1 - - - - 0.00000000005973 70.0
PYH1_k127_5758814_2 - - - - 0.0000000004971 62.0
PYH1_k127_5760829_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 554.0
PYH1_k127_5760829_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 439.0
PYH1_k127_5760829_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 253.0
PYH1_k127_5760829_3 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000719 216.0
PYH1_k127_5784565_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 475.0
PYH1_k127_5784565_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 447.0
PYH1_k127_5784565_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000006035 265.0
PYH1_k127_5784565_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000008532 168.0
PYH1_k127_5784565_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000164 162.0
PYH1_k127_5784565_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000001842 145.0
PYH1_k127_5809669_0 Response regulator, receiver K01007 - 2.7.9.2 4.991e-217 687.0
PYH1_k127_582322_0 Cytochrome c554 and c-prime - - - 2.369e-219 693.0
PYH1_k127_5846922_0 RNA ligase activity K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 555.0
PYH1_k127_5846922_1 Oligoendopeptidase f K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 527.0
PYH1_k127_5846922_2 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 308.0
PYH1_k127_5846922_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000003376 239.0
PYH1_k127_5846922_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000001346 196.0
PYH1_k127_5846922_5 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000001861 162.0
PYH1_k127_5846922_6 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000041 105.0
PYH1_k127_5888686_0 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1058.0
PYH1_k127_5888686_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 585.0
PYH1_k127_5888686_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 467.0
PYH1_k127_5888686_3 PFAM HypF finger K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
PYH1_k127_5888686_4 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000002759 112.0
PYH1_k127_5888686_5 Methyltransferase domain - - - 0.00000000002488 73.0
PYH1_k127_58982_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000000000000000009483 166.0
PYH1_k127_58982_1 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000002584 73.0
PYH1_k127_58982_2 Outer membrane efflux protein - - - 0.0000001939 60.0
PYH1_k127_5907659_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 1.357e-211 668.0
PYH1_k127_5908883_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 481.0
PYH1_k127_5908883_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000005772 140.0
PYH1_k127_5919793_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000009638 170.0
PYH1_k127_5919793_1 Histidine kinase - - - 0.0000000000000000000000000006696 131.0
PYH1_k127_5927599_0 Domain of unknown function (DUF3471) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 512.0
PYH1_k127_5936888_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000001935 207.0
PYH1_k127_5939790_0 PFAM peptidase U34 dipeptidase - - - 5.285e-198 630.0
PYH1_k127_5939790_1 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 510.0
PYH1_k127_5939790_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102,K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 350.0
PYH1_k127_595013_0 PFAM aminotransferase class V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 349.0
PYH1_k127_595013_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000002473 206.0
PYH1_k127_5953375_0 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 335.0
PYH1_k127_5953375_1 enterotoxin - - - 0.00000000000004493 79.0
PYH1_k127_5978439_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 389.0
PYH1_k127_5978439_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000156 270.0
PYH1_k127_5978439_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000001552 59.0
PYH1_k127_5982685_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 4.135e-208 657.0
PYH1_k127_5983173_0 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 483.0
PYH1_k127_5983173_1 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.00000000000000000000000000000000000001234 161.0
PYH1_k127_5983173_2 Transcriptional regulator - - - 0.00000000000006766 78.0
PYH1_k127_5983173_3 Putative regulatory protein - - - 0.0000001994 54.0
PYH1_k127_6031144_0 Tricorn protease C1 domain K08676 - - 0.0 1118.0
PYH1_k127_603626_0 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000000000000000000000000003385 194.0
PYH1_k127_603626_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000003843 70.0
PYH1_k127_603626_2 RNase_H superfamily - - - 0.00000007853 60.0
PYH1_k127_6044465_0 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000003405 196.0
PYH1_k127_6044465_1 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000002748 150.0
PYH1_k127_6044465_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000001152 93.0
PYH1_k127_6053892_0 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000004121 180.0
PYH1_k127_6074075_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 507.0
PYH1_k127_6074075_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 384.0
PYH1_k127_6074075_2 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000000000001633 136.0
PYH1_k127_6074075_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000007222 112.0
PYH1_k127_6074075_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000698 75.0
PYH1_k127_6113155_0 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 436.0
PYH1_k127_6113155_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 299.0
PYH1_k127_6113155_2 Tricorn protease C1 domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
PYH1_k127_6113155_3 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000001274 175.0
PYH1_k127_6113155_4 metallocarboxypeptidase activity - - - 0.000000000000000002303 101.0
PYH1_k127_6118715_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005866 276.0
PYH1_k127_6118715_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000007535 224.0
PYH1_k127_6118715_2 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000002865 178.0
PYH1_k127_6118715_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000001608 143.0
PYH1_k127_6118715_4 PFAM Cell envelope-related transcriptional attenuator domain - - - 0.0000000117 63.0
PYH1_k127_6118715_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001973 62.0
PYH1_k127_6118715_7 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.0009028 47.0
PYH1_k127_6141549_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000007431 218.0
PYH1_k127_6141549_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000001202 138.0
PYH1_k127_6141549_2 ABC transporter K02003 - - 0.00000000000000000000000000001212 124.0
PYH1_k127_6158222_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 8.718e-257 809.0
PYH1_k127_6158222_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 5.254e-247 783.0
PYH1_k127_6158222_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 544.0
PYH1_k127_6158222_3 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 540.0
PYH1_k127_6162665_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 595.0
PYH1_k127_6162665_1 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000000004135 117.0
PYH1_k127_6232509_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 338.0
PYH1_k127_6232509_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000008372 185.0
PYH1_k127_6232509_2 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000005552 94.0
PYH1_k127_6282805_0 Carbamoyltransferase C-terminus K00612 - - 1.002e-264 825.0
PYH1_k127_6282805_1 - - - - 0.00000000000000000114 87.0
PYH1_k127_6289166_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007334 274.0
PYH1_k127_6289166_1 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000008299 166.0
PYH1_k127_6289166_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000002871 76.0
PYH1_k127_6299813_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
PYH1_k127_6299813_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000004458 116.0
PYH1_k127_6300372_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
PYH1_k127_6300372_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000001645 220.0
PYH1_k127_6331107_0 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000001856 177.0
PYH1_k127_6331107_1 metal-dependent membrane protease K07052 - - 0.0000000000000001806 87.0
PYH1_k127_633495_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 473.0
PYH1_k127_633495_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000001273 182.0
PYH1_k127_633495_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000001264 164.0
PYH1_k127_633495_3 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000004146 106.0
PYH1_k127_633605_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 438.0
PYH1_k127_633605_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000003745 121.0
PYH1_k127_633605_2 HEAT repeats - - - 0.00004878 52.0
PYH1_k127_633910_0 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 443.0
PYH1_k127_633910_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003278 242.0
PYH1_k127_6382577_0 Oligopeptide transporter OPT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 522.0
PYH1_k127_6405551_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 340.0
PYH1_k127_6405551_1 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000002812 169.0
PYH1_k127_6464170_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.802e-319 995.0
PYH1_k127_6464170_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.658e-267 839.0
PYH1_k127_6464170_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000256 199.0
PYH1_k127_6464170_3 Protein of unknown function (DUF721) - - - 0.00000000000004212 76.0
PYH1_k127_6465314_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1143.0
PYH1_k127_6465314_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
PYH1_k127_6465314_2 PQQ-like domain - - - 0.000000000000000000000000000000000001369 144.0
PYH1_k127_6465314_3 Cold shock K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000191 86.0
PYH1_k127_6465314_4 Protein of unknown function (DUF494) - - - 0.0001077 50.0
PYH1_k127_6481240_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.031e-258 811.0
PYH1_k127_6481240_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 378.0
PYH1_k127_6481240_2 membrane organization K07277 - - 0.00000000000006527 82.0
PYH1_k127_6481240_3 Tetratricopeptide repeats - - - 0.00000000001327 76.0
PYH1_k127_6483766_0 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 320.0
PYH1_k127_6483766_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 312.0
PYH1_k127_6483766_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000001394 165.0
PYH1_k127_6496748_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.809e-219 707.0
PYH1_k127_6496748_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000005887 237.0
PYH1_k127_6496748_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000009761 68.0
PYH1_k127_6496748_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000002354 57.0
PYH1_k127_6496748_4 antisigma factor binding K04749 - - 0.0003084 50.0
PYH1_k127_6498487_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000001018 164.0
PYH1_k127_6498487_1 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001936 145.0
PYH1_k127_6498487_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000004981 121.0
PYH1_k127_6498487_3 rRNA binding K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000433 98.0
PYH1_k127_6498487_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000001323 93.0
PYH1_k127_6507808_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 614.0
PYH1_k127_6508036_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 545.0
PYH1_k127_6508036_1 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.0000000000000006895 81.0
PYH1_k127_6526965_0 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000008928 218.0
PYH1_k127_6526965_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000005113 154.0
PYH1_k127_6564656_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 1.278e-288 890.0
PYH1_k127_6611208_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 406.0
PYH1_k127_6611810_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.235e-219 693.0
PYH1_k127_6611810_1 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000002445 119.0
PYH1_k127_6611810_2 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000003743 107.0
PYH1_k127_6611810_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000001184 78.0
PYH1_k127_6615979_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000001486 231.0
PYH1_k127_6615979_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000001663 211.0
PYH1_k127_6639480_0 ABC-2 family transporter protein K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 339.0
PYH1_k127_6639480_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000003928 228.0
PYH1_k127_6639480_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000001117 79.0
PYH1_k127_6639480_3 AAA domain, putative AbiEii toxin, Type IV TA system K09697 - 3.6.3.7 0.0000008455 51.0
PYH1_k127_6643904_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 475.0
PYH1_k127_6643904_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 405.0
PYH1_k127_6643904_2 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 356.0
PYH1_k127_6645089_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 383.0
PYH1_k127_6645089_1 Adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.000000000000000000000000000001705 126.0
PYH1_k127_6677211_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 3.761e-285 888.0
PYH1_k127_6677211_1 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000006424 184.0
PYH1_k127_6693028_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 346.0
PYH1_k127_6708832_0 ABC-type transport system involved in multi-copper enzyme maturation - - - 0.000000000000000000000000008502 119.0
PYH1_k127_6708832_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001965 119.0
PYH1_k127_6738349_0 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 382.0
PYH1_k127_6738349_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000003226 242.0
PYH1_k127_6738349_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000001969 209.0
PYH1_k127_6759571_0 DNA polymerase alpha chain like domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 594.0
PYH1_k127_67887_0 protein secretion - - - 0.00000000000000000000000000001179 135.0
PYH1_k127_6797771_0 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 342.0
PYH1_k127_6797771_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002518 280.0
PYH1_k127_6797771_2 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000001237 173.0
PYH1_k127_6797771_3 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000002282 80.0
PYH1_k127_6887058_0 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 466.0
PYH1_k127_6887058_1 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.6.1.13 0.0000000000000000000000000000000000001627 149.0
PYH1_k127_6907635_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 354.0
PYH1_k127_6909510_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004317 239.0
PYH1_k127_6909510_1 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000005083 179.0
PYH1_k127_6909510_2 - - - - 0.0000000006217 67.0
PYH1_k127_6957881_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.0000000000000000008065 87.0
PYH1_k127_6957881_1 heptosyltransferase II K02843 - - 0.00000000002176 75.0
PYH1_k127_6957881_2 ABC transporter K02021,K06147,K06148,K11085 - - 0.0000009244 56.0
PYH1_k127_6992571_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000004397 154.0
PYH1_k127_6992571_1 Tetratricopeptide repeat - - - 0.0000000162 64.0
PYH1_k127_6992571_2 metallopeptidase activity - - - 0.0000003102 64.0
PYH1_k127_6995343_0 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008054 255.0
PYH1_k127_6995343_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000005618 222.0
PYH1_k127_7040111_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 412.0
PYH1_k127_7040111_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 313.0
PYH1_k127_7040111_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000001963 225.0
PYH1_k127_704731_0 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 494.0
PYH1_k127_704731_1 citrate CoA-transferase activity K01643 - 2.8.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005291 275.0
PYH1_k127_7086568_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 564.0
PYH1_k127_7138612_0 PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 581.0
PYH1_k127_7138612_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 315.0
PYH1_k127_7138612_2 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000247 147.0
PYH1_k127_7138612_3 GYD domain - - - 0.00000000000000000000000000000000003956 136.0
PYH1_k127_7138612_4 - - - - 0.000000006453 66.0
PYH1_k127_7161200_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000866 244.0
PYH1_k127_7161200_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000309 151.0
PYH1_k127_7161200_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000344 93.0
PYH1_k127_7161200_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000009177 90.0
PYH1_k127_7161200_4 Belongs to the UPF0109 family K06960 - - 0.0000000000000002059 82.0
PYH1_k127_7178063_0 Tricorn protease C1 domain K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000566 269.0
PYH1_k127_7185738_0 Cystathionine beta-synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000004803 264.0
PYH1_k127_7185738_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000006853 182.0
PYH1_k127_7185738_2 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000001115 171.0
PYH1_k127_7185738_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000002069 117.0
PYH1_k127_7185738_4 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.0000000000000000000000000002262 117.0
PYH1_k127_7212445_0 - - - - 0.00000000000000000000003284 101.0
PYH1_k127_7212445_1 SNF2 family N-terminal domain - - - 0.000000000000000000006024 96.0
PYH1_k127_7212445_2 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000002228 95.0
PYH1_k127_7212445_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000808 63.0
PYH1_k127_7220600_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 344.0
PYH1_k127_7220600_1 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007094 258.0
PYH1_k127_7220600_2 Protein of unknown function (DUF456) K09793 - - 0.00000000006855 69.0
PYH1_k127_7220790_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000005098 207.0
PYH1_k127_7220790_1 PFAM Glycosyl transferases group 1 - - - 0.00000008695 61.0
PYH1_k127_7245733_0 HI0933-like protein K07007 - - 0.000000000000000000000000000003235 121.0
PYH1_k127_7245733_1 Multicopper oxidase K04753 - - 0.000000000000000000000000001478 130.0
PYH1_k127_7245733_2 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000008673 88.0
PYH1_k127_724727_0 Soluble NSF attachment protein, SNAP - - - 0.0000000000000000000000000000000005351 138.0
PYH1_k127_724727_1 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000001257 122.0
PYH1_k127_724727_2 - - - - 0.0000000000000000001836 96.0
PYH1_k127_724727_3 Zinc-dependent metalloprotease - - - 0.000000000000003688 91.0
PYH1_k127_7259042_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 321.0
PYH1_k127_7259042_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 304.0
PYH1_k127_7261663_0 Type III restriction enzyme res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 585.0
PYH1_k127_7273224_0 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000005196 220.0
PYH1_k127_7273224_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000288 119.0
PYH1_k127_728869_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 1.962e-317 994.0
PYH1_k127_728869_1 PFAM natural resistance-associated macrophage protein K03322 - - 4.872e-199 629.0
PYH1_k127_728869_2 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 491.0
PYH1_k127_728869_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 312.0
PYH1_k127_728869_4 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
PYH1_k127_728869_5 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000008149 168.0
PYH1_k127_728869_6 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000006497 148.0
PYH1_k127_728869_7 Phosphate transporter family K03306 - - 0.000000000000000009972 83.0
PYH1_k127_728869_8 Glycosyltransferase, group 2 family protein - - - 0.0000000001675 64.0
PYH1_k127_7295755_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 382.0
PYH1_k127_7311551_0 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 434.0
PYH1_k127_7311551_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000246 145.0
PYH1_k127_7311551_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000000000002158 138.0
PYH1_k127_7311551_3 PFAM Appr-1-p processing - - - 0.0000000000006179 77.0
PYH1_k127_7322394_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003029 269.0
PYH1_k127_7330003_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 352.0
PYH1_k127_7330003_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 344.0
PYH1_k127_7330003_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000001719 132.0
PYH1_k127_7377574_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008363 248.0
PYH1_k127_741016_0 class II (D K and N) K01893 - 6.1.1.22 0.000000000000005973 79.0
PYH1_k127_741016_1 Sel1-like repeats. - - - 0.000002124 61.0
PYH1_k127_7424669_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 597.0
PYH1_k127_744587_0 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 602.0
PYH1_k127_744587_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 413.0
PYH1_k127_744587_2 mRNA catabolic process K06950,K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004369 269.0
PYH1_k127_744587_3 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000054 212.0
PYH1_k127_7451267_0 Chain length determinant protein K01153,K05789,K07011,K16554 - 3.1.21.3 0.0000000000000000000000000000000000000000005888 172.0
PYH1_k127_7463836_0 PQQ enzyme repeat - - - 0.000000000000000000000001308 118.0
PYH1_k127_7463836_1 Tetratricopeptide repeat - - - 0.0000000000000004129 89.0
PYH1_k127_7463836_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000005237 72.0
PYH1_k127_7486063_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000004797 184.0
PYH1_k127_7486063_1 lipopolysaccharide metabolic process K07502,K08309,K19804,K21572 - - 0.00000001143 61.0
PYH1_k127_7503659_0 adenosylhomocysteinase activity K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 606.0
PYH1_k127_7503659_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 273.0
PYH1_k127_7508614_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
PYH1_k127_7508614_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000001665 134.0
PYH1_k127_7514361_0 PFAM Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 8.536e-199 635.0
PYH1_k127_7514361_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 370.0
PYH1_k127_7514361_2 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.0000000000000000000000000000006819 130.0
PYH1_k127_7514361_3 CAAX amino terminal protease family K07052 - - 0.00002474 54.0
PYH1_k127_7516885_0 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 297.0
PYH1_k127_7516885_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000002759 231.0
PYH1_k127_7516885_2 cellulose binding - - - 0.0000355 46.0
PYH1_k127_7570748_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000005572 196.0
PYH1_k127_7570748_1 histidyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000000000002376 199.0
PYH1_k127_7570748_2 Tellurite resistance protein TerB - - - 0.000000000000000000000002744 111.0
PYH1_k127_7570748_3 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000001958 113.0
PYH1_k127_7570748_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000001176 79.0
PYH1_k127_7576967_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 5.157e-231 727.0
PYH1_k127_7610066_0 Involved in the tonB-independent uptake of proteins K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 385.0
PYH1_k127_7610066_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 303.0
PYH1_k127_7613417_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 9.39e-220 698.0
PYH1_k127_7613417_1 Flavodoxin-like fold K03923,K11748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002599 263.0
PYH1_k127_7613417_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000001021 130.0
PYH1_k127_7613417_3 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000933 133.0
PYH1_k127_7613417_4 EamA-like transporter family - - - 0.00000006743 63.0
PYH1_k127_7614710_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000001017 212.0
PYH1_k127_7614710_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000003023 136.0
PYH1_k127_7647961_0 DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000008855 231.0
PYH1_k127_7647961_1 Polysaccharide biosynthesis protein K01710 - 4.2.1.46 0.00000000000000000000000000000004863 128.0
PYH1_k127_7647961_2 PFAM BioY family K03523 - - 0.0000000000000000194 96.0
PYH1_k127_7664748_0 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000000000000000001261 222.0
PYH1_k127_7664748_1 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000001951 216.0
PYH1_k127_7674807_0 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 339.0
PYH1_k127_7674807_1 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 336.0
PYH1_k127_7674807_2 AsmA-like C-terminal region K07289 - - 0.000000001233 68.0
PYH1_k127_7678545_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 452.0
PYH1_k127_7678545_1 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
PYH1_k127_7678545_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
PYH1_k127_7679745_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 529.0
PYH1_k127_7679745_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 355.0
PYH1_k127_7679745_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000002631 190.0
PYH1_k127_7679745_3 metallopeptidase activity K01218,K13276 - 3.2.1.78 0.00000000000000003149 91.0
PYH1_k127_7679803_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 358.0
PYH1_k127_7679803_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 338.0
PYH1_k127_7679803_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001431 272.0
PYH1_k127_7679803_3 Glycine cleavage system H protein K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000005346 152.0
PYH1_k127_7730114_0 FAD dependent oxidoreductase K00205,K00362,K02573,K03518,K05927,K07302 - 1.12.5.1,1.2.5.3,1.3.99.16,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 487.0
PYH1_k127_7730114_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 309.0
PYH1_k127_7749432_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000008231 173.0
PYH1_k127_7749432_2 cellulose binding K00505 - 1.14.18.1 0.00000000003721 74.0
PYH1_k127_7757680_0 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 347.0
PYH1_k127_7757680_1 SurA N-terminal domain K07533 - 5.2.1.8 0.0000000000000000066 94.0
PYH1_k127_7780076_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008077 269.0
PYH1_k127_7780076_1 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000001039 116.0
PYH1_k127_7780076_2 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000006425 109.0
PYH1_k127_7780076_3 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000005068 83.0
PYH1_k127_7780076_4 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000002345 62.0
PYH1_k127_7788113_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.331e-272 845.0
PYH1_k127_7788193_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 423.0
PYH1_k127_7788193_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 339.0
PYH1_k127_7788193_2 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001514 251.0
PYH1_k127_7793246_0 Extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 344.0
PYH1_k127_7793246_1 TIGRFAM sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001018 286.0
PYH1_k127_7793246_2 TIGRFAM sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007287 274.0
PYH1_k127_7795042_0 Helix-turn-helix domain - - - 0.0000000000000003769 83.0
PYH1_k127_7795042_1 transcriptional regulators - - - 0.00000000000000851 79.0
PYH1_k127_7795042_2 PFAM GvpD gas vesicle - - - 0.00000000007375 70.0
PYH1_k127_7812757_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 464.0
PYH1_k127_7812757_1 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000147 128.0
PYH1_k127_7812757_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000002037 66.0
PYH1_k127_7820582_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 426.0
PYH1_k127_7820582_1 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 413.0
PYH1_k127_7820582_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001049 278.0
PYH1_k127_7820582_3 Male sterility protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000006346 219.0
PYH1_k127_7820582_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000001773 207.0
PYH1_k127_7820582_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000004396 166.0
PYH1_k127_7820582_6 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000006505 169.0
PYH1_k127_7820582_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000007231 153.0
PYH1_k127_7827385_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 496.0
PYH1_k127_7827385_1 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000122 182.0
PYH1_k127_7827385_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000002544 88.0
PYH1_k127_7827385_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.000000000000000006324 86.0
PYH1_k127_7832531_0 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 340.0
PYH1_k127_7832531_1 Haloacid dehalogenase-like hydrolase K01507 - 3.6.1.1 0.00000000000000000000000000002056 124.0
PYH1_k127_7832531_2 30S ribosomal protein Thx K19033 - - 0.0006171 45.0
PYH1_k127_7880181_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 331.0
PYH1_k127_7891020_0 Glycosyl hydrolase family 92 - - - 6.618e-261 820.0
PYH1_k127_7897249_0 PFAM Mandelate racemase muconate lactonizing protein K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001595 254.0
PYH1_k127_7897249_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000003434 130.0
PYH1_k127_7897249_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000603 87.0
PYH1_k127_7897249_4 Belongs to the serpin family K05579,K13963 - 1.6.5.3 0.000000291 52.0
PYH1_k127_7904534_0 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 327.0
PYH1_k127_7904534_1 TrkA-N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002121 232.0
PYH1_k127_7904534_2 ECF sigma factor K03088 - - 0.0000000000000000000000003253 112.0
PYH1_k127_7906640_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 295.0
PYH1_k127_7906640_1 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000007427 210.0
PYH1_k127_7906640_2 - - - - 0.0000000000000003914 79.0
PYH1_k127_7909445_0 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001862 269.0
PYH1_k127_7909445_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000002444 168.0
PYH1_k127_7909445_2 Transposase - - - 0.00000000000000000000000000000000000002331 145.0
PYH1_k127_7909445_3 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000002565 147.0
PYH1_k127_7909445_4 PFAM Integrase catalytic - - - 0.000000000007848 70.0
PYH1_k127_7915687_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 463.0
PYH1_k127_7915687_1 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000001671 181.0
PYH1_k127_7948884_0 response regulator K02481,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000482 287.0
PYH1_k127_7948884_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001064 248.0
PYH1_k127_7948884_2 domain, Protein - - - 0.0000000000000000000000000000000006203 149.0
PYH1_k127_7949837_0 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000002665 175.0
PYH1_k127_7949837_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000001743 151.0
PYH1_k127_7953281_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.609e-200 638.0
PYH1_k127_8038814_0 DNA polymerase A domain K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000009735 211.0
PYH1_k127_8038814_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000127 192.0
PYH1_k127_8038814_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000009369 123.0
PYH1_k127_805715_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 8.212e-236 753.0
PYH1_k127_805715_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.162e-209 666.0
PYH1_k127_805715_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 319.0
PYH1_k127_8070742_0 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 330.0
PYH1_k127_8070742_1 Regulatory protein, FmdB family - - - 0.0000000000000000000004137 98.0
PYH1_k127_8071579_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.835e-230 727.0
PYH1_k127_8074422_0 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000006525 211.0
PYH1_k127_8074422_1 Stage II sporulation protein K06381 - - 0.00000000000000001301 85.0
PYH1_k127_8074422_2 Belongs to the glycosyl hydrolase 13 family - - - 0.0000001286 56.0
PYH1_k127_8076223_0 long-chain fatty acid transporting porin activity - - - 0.0000000005585 68.0
PYH1_k127_8076223_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000003143 67.0
PYH1_k127_8117950_0 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
PYH1_k127_8117950_1 Transglycosylase - - - 0.00000000009927 67.0
PYH1_k127_8117950_2 - - - - 0.0000000004905 70.0
PYH1_k127_8128492_0 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 327.0
PYH1_k127_8128492_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001793 259.0
PYH1_k127_8128492_2 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000003181 253.0
PYH1_k127_8128492_3 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000000000008684 123.0
PYH1_k127_8151090_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 1.227e-220 695.0
PYH1_k127_8170567_0 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 329.0
PYH1_k127_8170567_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000000000000000008924 210.0
PYH1_k127_8170567_2 TetR family transcriptional regulator - - - 0.000000000002894 76.0
PYH1_k127_8171783_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 490.0
PYH1_k127_8182799_0 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 7.452e-269 845.0
PYH1_k127_8182799_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000000000000005742 189.0
PYH1_k127_8182799_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000003829 61.0
PYH1_k127_8186216_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 526.0
PYH1_k127_8186216_1 Bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001745 266.0
PYH1_k127_8186216_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000001802 250.0
PYH1_k127_8204955_0 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000166 233.0
PYH1_k127_8204955_1 Belongs to the uridine kinase family K00876 - 2.7.1.48 0.000000000000000000000000000000000002788 143.0
PYH1_k127_8213641_0 PFAM binding-protein-dependent transport systems inner membrane component K02025,K17242 - - 0.00000000000000000000000000000000000000000000000000000000000000000001966 243.0
PYH1_k127_8213641_1 binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000007861 233.0
PYH1_k127_8229407_0 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 469.0
PYH1_k127_8229407_1 FlgD Ig-like domain K21449 - - 0.00000000000000000000000000000000000000000000003723 190.0
PYH1_k127_8229407_2 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000000000000000000000008755 119.0
PYH1_k127_8229407_3 IMP dehydrogenase activity K07182 - - 0.0000000000000001576 85.0
PYH1_k127_8256461_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 478.0
PYH1_k127_8275278_0 PglZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 560.0
PYH1_k127_8275278_1 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001753 292.0
PYH1_k127_8275278_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 272.0
PYH1_k127_8275278_3 Hydrolase, P-loop family K06925 - - 0.00000000000000000000000004851 113.0
PYH1_k127_8275278_4 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000003095 113.0
PYH1_k127_8275278_5 Acetyltransferase K03789 - 2.3.1.128 0.000000000003384 70.0
PYH1_k127_8275278_6 Cupin 2, conserved barrel domain protein - - - 0.0000002563 53.0
PYH1_k127_8278999_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1172.0
PYH1_k127_8301700_0 PUA-like domain K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 440.0
PYH1_k127_8301700_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000004686 177.0
PYH1_k127_8320376_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 545.0
PYH1_k127_8320376_1 Dodecin K09165 - - 0.0000000000000000000000000001978 120.0
PYH1_k127_8320376_2 - - - - 0.0000000000000000144 87.0
PYH1_k127_8320376_3 PFAM Major facilitator superfamily - - - 0.000000000001948 70.0
PYH1_k127_8320376_4 Thioredoxin domain - - - 0.00005403 47.0
PYH1_k127_8337795_0 Methyltransferase - - - 0.0000000000000000000000000000000000000000000009763 173.0
PYH1_k127_8337795_1 Nickel-containing superoxide dismutase - - - 0.0000000000000000000000000000000000000002726 154.0
PYH1_k127_8346145_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 570.0
PYH1_k127_8346145_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 437.0
PYH1_k127_8346145_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 384.0
PYH1_k127_8346145_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.0000000000000000000000000000000001259 137.0
PYH1_k127_8354306_0 Glycosyltransferase like family 2 K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 437.0
PYH1_k127_8354306_1 Belongs to the ompA family K03286 - - 0.0000000000000000000004183 97.0
PYH1_k127_8354306_2 Tetratrico peptide repeat - - - 0.000000005849 69.0
PYH1_k127_8369966_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001845 238.0
PYH1_k127_8369966_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000002347 136.0
PYH1_k127_870940_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 486.0
PYH1_k127_870940_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000008486 199.0
PYH1_k127_893669_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.624e-221 701.0
PYH1_k127_893669_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000001421 133.0
PYH1_k127_893669_2 TIGRFAM M6 family metalloprotease domain - - - 0.0000000000000000000000000000001192 145.0
PYH1_k127_893669_3 cellulase activity K01201 - 3.2.1.45 0.0000000000001593 85.0
PYH1_k127_893669_4 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000001297 69.0
PYH1_k127_907803_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 451.0
PYH1_k127_907803_1 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000165 277.0
PYH1_k127_959979_0 PFAM Cytochrome c assembly protein K02198 - - 0.00000000000000000000000000000000000000000002548 168.0
PYH1_k127_959979_1 - - - - 0.0005539 47.0
PYH1_k127_982066_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 344.0
PYH1_k127_982066_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 304.0
PYH1_k127_982066_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000472 275.0
PYH1_k127_982066_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000007125 218.0
PYH1_k127_982066_4 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000001576 207.0
PYH1_k127_982066_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000005597 117.0
PYH1_k127_982066_6 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.00000000000000000000008975 104.0
PYH1_k127_983082_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000003253 206.0
PYH1_k127_983082_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000001312 178.0
PYH1_k127_984732_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 3.824e-222 714.0
PYH1_k127_984732_1 inorganic phosphate transmembrane transporter activity K02038 - - 0.00000000000000000000000000000000000000000000006702 179.0