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Overview

ID MAG03170
Name PYH1_bin.70
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family JAFGLR01
Genus JAFGLR01
Species
Assembly information
Completeness (%) 84.21
Contamination (%) 3.31
GC content (%) 51.0
N50 (bp) 4,039
Genome size (bp) 1,370,910

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1353

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1016639_0 NurA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
PYH1_k127_1016639_1 PFAM HAS barrel domain - - - 0.0000000002249 63.0
PYH1_k127_1031534_0 Hep Hag repeat protein K21449 - - 0.00000000000000000000000000000000000000000000000000002104 193.0
PYH1_k127_1031534_2 - - - - 0.00000000318 58.0
PYH1_k127_1081425_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000007981 198.0
PYH1_k127_1081425_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000242 98.0
PYH1_k127_1081425_2 phosphatidylinositol transporter activity - - - 0.000000000000000001862 90.0
PYH1_k127_1081425_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000006102 62.0
PYH1_k127_1118983_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 542.0
PYH1_k127_1118983_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 501.0
PYH1_k127_1118983_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000004948 168.0
PYH1_k127_1118983_11 Probable zinc-ribbon domain - - - 0.00000000000009402 77.0
PYH1_k127_1118983_12 Putative zinc- or iron-chelating domain - - - 0.0000000000001949 75.0
PYH1_k127_1118983_13 Phage integrase family - - - 0.000000008631 57.0
PYH1_k127_1118983_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 485.0
PYH1_k127_1118983_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 416.0
PYH1_k127_1118983_4 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001196 288.0
PYH1_k127_1118983_5 PFAM Response regulator receiver domain K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH1_k127_1118983_6 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000002445 246.0
PYH1_k127_1118983_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.000000000000000000000000000000000000000000000000000000000000001233 226.0
PYH1_k127_1118983_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001977 209.0
PYH1_k127_1118983_9 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000006245 184.0
PYH1_k127_1149667_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000002386 160.0
PYH1_k127_1149667_1 ISXO2-like transposase domain K07488 - - 0.0000000000000000000000000008328 123.0
PYH1_k127_1152100_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 451.0
PYH1_k127_1152100_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008076 281.0
PYH1_k127_1181198_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008169 259.0
PYH1_k127_1181198_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000008592 59.0
PYH1_k127_1181198_2 dehydratase - - - 0.0001155 49.0
PYH1_k127_119302_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 458.0
PYH1_k127_119302_1 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000463 186.0
PYH1_k127_1208612_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 298.0
PYH1_k127_1208612_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 286.0
PYH1_k127_1208612_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000005902 150.0
PYH1_k127_1208612_3 - - - - 0.000368 49.0
PYH1_k127_1231333_0 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 298.0
PYH1_k127_1231333_1 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000002152 96.0
PYH1_k127_1243501_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000001292 155.0
PYH1_k127_126938_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 371.0
PYH1_k127_127866_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.394e-286 892.0
PYH1_k127_127866_1 GPR1 FUN34 yaaH family protein K07034 - - 0.00000000000000000000000000000000000000007001 157.0
PYH1_k127_127866_2 Probable zinc-ribbon domain - - - 0.00000001528 55.0
PYH1_k127_127866_3 Probable zinc-ribbon domain - - - 0.00007066 46.0
PYH1_k127_1280737_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 512.0
PYH1_k127_1280737_1 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000008714 89.0
PYH1_k127_1331056_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 291.0
PYH1_k127_1331056_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 289.0
PYH1_k127_1331056_2 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006778 265.0
PYH1_k127_1331056_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000002032 137.0
PYH1_k127_1331056_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000007743 94.0
PYH1_k127_1338461_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 472.0
PYH1_k127_1349122_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
PYH1_k127_1349122_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000323 131.0
PYH1_k127_1349122_2 cell adhesion involved in biofilm formation K07407 - 3.2.1.22 0.00000000000000000000000000000003375 137.0
PYH1_k127_1363798_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 404.0
PYH1_k127_1363798_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000436 241.0
PYH1_k127_1376956_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 549.0
PYH1_k127_1376956_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000002473 128.0
PYH1_k127_1429095_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 448.0
PYH1_k127_1440957_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 387.0
PYH1_k127_1440957_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.000000000000000000000000000000000000000001445 158.0
PYH1_k127_145694_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 549.0
PYH1_k127_145694_2 4 iron, 4 sulfur cluster binding - - - 0.00000000009453 63.0
PYH1_k127_1459677_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 463.0
PYH1_k127_1473578_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 391.0
PYH1_k127_1473578_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007817 278.0
PYH1_k127_1473578_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000004675 139.0
PYH1_k127_1473578_3 Domain of unknown function (DUF4129) - - - 0.0000007107 62.0
PYH1_k127_1492274_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000001076 179.0
PYH1_k127_1492274_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000382 71.0
PYH1_k127_1501668_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.056e-212 673.0
PYH1_k127_1526537_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 383.0
PYH1_k127_1526537_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000001112 122.0
PYH1_k127_1526537_2 META domain protein - - - 0.00000000003993 76.0
PYH1_k127_1538207_0 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 465.0
PYH1_k127_1538207_1 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
PYH1_k127_1545707_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 551.0
PYH1_k127_1545707_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
PYH1_k127_1545707_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000002672 55.0
PYH1_k127_1554795_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.24e-310 960.0
PYH1_k127_1554795_1 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000001589 88.0
PYH1_k127_1564436_0 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000002201 209.0
PYH1_k127_1564436_1 PFAM Cold-shock protein DNA-binding - - - 0.00000000000000000000000001078 115.0
PYH1_k127_1564436_2 AMP binding - - - 0.0000000000000000000000000543 113.0
PYH1_k127_1586009_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 371.0
PYH1_k127_1586009_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 311.0
PYH1_k127_1586009_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
PYH1_k127_1586009_3 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000008471 162.0
PYH1_k127_1586009_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000008817 81.0
PYH1_k127_1589107_0 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0 1482.0
PYH1_k127_1589107_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000004454 109.0
PYH1_k127_1589107_2 Transcriptional regulator, arsR family - - - 0.00000000000000000006103 93.0
PYH1_k127_1589107_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0006879 45.0
PYH1_k127_1596766_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 9.242e-197 620.0
PYH1_k127_1596766_1 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000002796 166.0
PYH1_k127_1623678_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
PYH1_k127_1623678_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00973,K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8 0.000000000000000000000002318 114.0
PYH1_k127_1628210_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1405.0
PYH1_k127_1628210_1 DNA-directed DNA polymerase activity K02337 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 545.0
PYH1_k127_1628210_2 - - - - 0.000000000000000000000000000000000000000000000002855 182.0
PYH1_k127_1628210_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000002765 75.0
PYH1_k127_1653934_0 Belongs to the 5'-nucleotidase family K01081,K07004,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 377.0
PYH1_k127_167167_0 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004142 268.0
PYH1_k127_1675217_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 355.0
PYH1_k127_1675217_1 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000274 194.0
PYH1_k127_1675217_2 AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000007058 190.0
PYH1_k127_1675217_3 peptidase M24 - - - 0.00000000000000000000000000000002996 141.0
PYH1_k127_1675217_4 oxalate decarboxylase activity - - - 0.0000000000000003361 83.0
PYH1_k127_1675217_5 Hydantoin racemase K16841 - 5.1.99.3 0.00000000003931 74.0
PYH1_k127_1714537_0 DNA ligase K01971 - 6.5.1.1 6.586e-232 747.0
PYH1_k127_1714537_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000008496 179.0
PYH1_k127_1724465_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 437.0
PYH1_k127_1744614_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006963 273.0
PYH1_k127_1744614_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
PYH1_k127_1752923_0 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004931 276.0
PYH1_k127_1752923_1 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005234 272.0
PYH1_k127_1752923_2 glutaredoxin-like protein, YruB-family - - - 0.0000000000000000001733 89.0
PYH1_k127_1752923_3 Cation efflux family K16264 - - 0.000000006051 59.0
PYH1_k127_1769480_0 Putative Fe-S cluster K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 561.0
PYH1_k127_1769480_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000002293 267.0
PYH1_k127_1769480_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000006812 179.0
PYH1_k127_1779606_0 Baseplate J-like protein - - - 0.00000000000000000000000000005618 129.0
PYH1_k127_1792741_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
PYH1_k127_1792741_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000006346 79.0
PYH1_k127_1805726_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001126 261.0
PYH1_k127_1805726_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002525 256.0
PYH1_k127_1808247_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 467.0
PYH1_k127_1808247_1 Preprotein translocase subunit K03210 - - 0.00000000000000001751 87.0
PYH1_k127_1814138_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 564.0
PYH1_k127_1814138_1 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 552.0
PYH1_k127_1814138_2 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 462.0
PYH1_k127_1814138_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000001426 188.0
PYH1_k127_1820494_0 phage tail tape measure protein - - - 0.0000000000000002331 93.0
PYH1_k127_1820494_1 Protein of unknown function (DUF3277) - - - 0.0000000000000106 79.0
PYH1_k127_1820494_2 Protein of unknown function (DUF3383) - - - 0.0001416 44.0
PYH1_k127_1844281_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 471.0
PYH1_k127_1844281_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
PYH1_k127_1844281_2 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000003517 210.0
PYH1_k127_1844281_3 TIGRFAM type I restriction system adenine methylase (hsdM) K03427 - 2.1.1.72 0.0000000002886 63.0
PYH1_k127_1869940_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 387.0
PYH1_k127_1869940_1 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000003388 217.0
PYH1_k127_1869940_2 YHYH protein - - - 0.000000000000000000008621 100.0
PYH1_k127_1869940_3 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000001127 74.0
PYH1_k127_1869940_4 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000002707 67.0
PYH1_k127_1902552_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 413.0
PYH1_k127_1902552_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000001985 113.0
PYH1_k127_1941828_0 transmembrane transporter activity K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003761 261.0
PYH1_k127_1941828_1 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001978 256.0
PYH1_k127_1941828_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000001181 99.0
PYH1_k127_1941828_3 PFAM Sodium Bile acid symporter family K03325 - - 0.000000000000001497 77.0
PYH1_k127_1941828_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08738 - - 0.000003354 55.0
PYH1_k127_1944862_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 401.0
PYH1_k127_1944862_1 AAA domain K07028 - - 0.0000000000009229 76.0
PYH1_k127_1944862_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000003092 62.0
PYH1_k127_1944862_3 Psort location Cytoplasmic, score 8.87 - - - 0.0009065 44.0
PYH1_k127_1956274_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 289.0
PYH1_k127_1956274_1 Protein of unknown function (DUF1464) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 294.0
PYH1_k127_1956274_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000001284 174.0
PYH1_k127_1956274_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000008082 134.0
PYH1_k127_1959024_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 332.0
PYH1_k127_1964613_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000001266 203.0
PYH1_k127_1964613_1 4Fe-4S single cluster domain - - - 0.000000000000004899 87.0
PYH1_k127_1964613_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000007015 83.0
PYH1_k127_1964613_3 Major Facilitator Superfamily - - - 0.000000000001334 73.0
PYH1_k127_1964613_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000001373 58.0
PYH1_k127_1973651_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.474e-232 735.0
PYH1_k127_1973651_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 310.0
PYH1_k127_1973651_10 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000003163 108.0
PYH1_k127_1973651_11 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.000000000000001741 78.0
PYH1_k127_1973651_2 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 318.0
PYH1_k127_1973651_3 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
PYH1_k127_1973651_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
PYH1_k127_1973651_5 nitric oxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000248 197.0
PYH1_k127_1973651_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000000000609 184.0
PYH1_k127_1973651_7 metal-dependent hydrolase of the TIM-barrel fold K07045,K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000009363 173.0
PYH1_k127_1973651_8 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000002271 152.0
PYH1_k127_1973651_9 RNA methylase - - - 0.0000000000000000000000000000000000792 139.0
PYH1_k127_2019052_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 287.0
PYH1_k127_2019052_1 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000008006 205.0
PYH1_k127_2019052_2 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000003279 166.0
PYH1_k127_2019052_3 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000006171 128.0
PYH1_k127_2019052_4 Uncharacterised protein family UPF0066 - - - 0.00000000000000000011 92.0
PYH1_k127_2019052_5 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000003949 85.0
PYH1_k127_2094056_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.066e-246 767.0
PYH1_k127_2094056_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 605.0
PYH1_k127_2094056_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 537.0
PYH1_k127_2094056_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 473.0
PYH1_k127_2094056_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 457.0
PYH1_k127_2094056_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001041 251.0
PYH1_k127_2094056_6 MgtC family K07507 - - 0.00000000000000000000000000000000001328 140.0
PYH1_k127_2094056_7 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000001989 102.0
PYH1_k127_2094056_8 ACT domain K01653 - 2.2.1.6 0.00000000000000003649 82.0
PYH1_k127_2094056_9 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.0000000000000003553 81.0
PYH1_k127_2111202_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.772e-245 768.0
PYH1_k127_2111202_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 377.0
PYH1_k127_2111202_10 - - - - 0.0000000000000000000000006204 105.0
PYH1_k127_2111202_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 372.0
PYH1_k127_2111202_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 361.0
PYH1_k127_2111202_4 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 319.0
PYH1_k127_2111202_5 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000258 285.0
PYH1_k127_2111202_6 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000493 242.0
PYH1_k127_2111202_7 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000006091 193.0
PYH1_k127_2111202_8 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000007054 170.0
PYH1_k127_2111202_9 Cupin domain - - - 0.00000000000000000000000000000000002702 137.0
PYH1_k127_2122973_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 497.0
PYH1_k127_2122973_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000003484 117.0
PYH1_k127_212607_0 Amidohydrolase K07045,K14333,K15063 - 4.1.1.46 0.000000213 53.0
PYH1_k127_212607_1 Dihydroorotate dehydrogenase - - - 0.00001459 53.0
PYH1_k127_2162237_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 320.0
PYH1_k127_2162237_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 308.0
PYH1_k127_2162237_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000002469 129.0
PYH1_k127_2190497_0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000003116 160.0
PYH1_k127_2190497_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000001147 121.0
PYH1_k127_2190497_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000001867 113.0
PYH1_k127_2190497_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000001718 95.0
PYH1_k127_2259125_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.338e-231 724.0
PYH1_k127_2259125_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002512 284.0
PYH1_k127_227184_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1272.0
PYH1_k127_230027_0 Heat shock 70 kDa protein K04043 - - 1.006e-303 942.0
PYH1_k127_230027_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000004104 202.0
PYH1_k127_230027_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000007075 154.0
PYH1_k127_230027_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000007517 146.0
PYH1_k127_2320776_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000265 198.0
PYH1_k127_2320776_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000001102 151.0
PYH1_k127_2320776_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 4.2.1.17 0.0000000004652 61.0
PYH1_k127_2325215_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 1.493e-244 766.0
PYH1_k127_2325215_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000319 162.0
PYH1_k127_2325215_2 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000002783 60.0
PYH1_k127_2363746_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 290.0
PYH1_k127_2363746_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000111 178.0
PYH1_k127_2392607_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 316.0
PYH1_k127_2392607_1 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 263.0
PYH1_k127_2392607_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
PYH1_k127_2392607_3 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000004123 200.0
PYH1_k127_2490418_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 491.0
PYH1_k127_2495541_0 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
PYH1_k127_2495541_1 Protein of unknown function (DUF448) K07742 - - 0.0000000000003505 70.0
PYH1_k127_2504754_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 375.0
PYH1_k127_2504754_1 III protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 328.0
PYH1_k127_2504754_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 270.0
PYH1_k127_2504754_3 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000004069 196.0
PYH1_k127_2504754_4 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000344 102.0
PYH1_k127_2546261_0 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 359.0
PYH1_k127_2546261_1 diguanylate cyclase - - - 0.00000000000002048 81.0
PYH1_k127_2603778_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.015e-270 841.0
PYH1_k127_2603778_1 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000001214 179.0
PYH1_k127_2603778_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000001043 154.0
PYH1_k127_2614506_0 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 333.0
PYH1_k127_2625482_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
PYH1_k127_2625482_1 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000000000000000002342 213.0
PYH1_k127_2625482_2 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000005975 184.0
PYH1_k127_2625482_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000000000001737 156.0
PYH1_k127_2691891_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 574.0
PYH1_k127_2691891_1 Acetyl xylan esterase (AXE1) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 311.0
PYH1_k127_2691891_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001257 208.0
PYH1_k127_2691891_3 Major facilitator superfamily K03449 - - 0.0000000000000000000000000000000000000000000000000000000005007 209.0
PYH1_k127_2691891_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000009816 199.0
PYH1_k127_2691891_5 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000001919 111.0
PYH1_k127_2713930_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 570.0
PYH1_k127_2713930_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 313.0
PYH1_k127_2713930_10 - - - - 0.0000272 48.0
PYH1_k127_2713930_2 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 294.0
PYH1_k127_2713930_3 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000004419 219.0
PYH1_k127_2713930_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000008925 158.0
PYH1_k127_2713930_5 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000000000000000001045 160.0
PYH1_k127_2713930_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000004511 152.0
PYH1_k127_2713930_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000002061 144.0
PYH1_k127_2713930_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000008774 138.0
PYH1_k127_2713930_9 - - - - 0.000000000000000000000000000114 117.0
PYH1_k127_2721106_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000001994 72.0
PYH1_k127_2721106_1 Trypsin - - - 0.00000000003459 68.0
PYH1_k127_2721106_2 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.0006044 48.0
PYH1_k127_2748392_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
PYH1_k127_2748392_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000002661 213.0
PYH1_k127_2770772_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000001426 171.0
PYH1_k127_2770772_1 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000000000000006409 161.0
PYH1_k127_2770772_2 transcriptional regulator PadR family K10947 - - 0.00000000000000000000000002206 113.0
PYH1_k127_2779216_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 591.0
PYH1_k127_2779216_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004095 273.0
PYH1_k127_2867052_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 473.0
PYH1_k127_2867052_1 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 372.0
PYH1_k127_2867052_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 263.0
PYH1_k127_2867052_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003928 243.0
PYH1_k127_2867052_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
PYH1_k127_2882336_0 4Fe-4S dicluster domain - - - 1.21e-229 722.0
PYH1_k127_2882336_1 PFAM Nitrate reductase gamma subunit - - - 0.0000000000001029 73.0
PYH1_k127_2882336_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000001224 55.0
PYH1_k127_2882336_3 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000001395 51.0
PYH1_k127_2891720_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 589.0
PYH1_k127_2891720_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 555.0
PYH1_k127_2891720_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000002276 100.0
PYH1_k127_2891720_3 Mannose-6-phosphate isomerase - - - 0.0002559 46.0
PYH1_k127_2929806_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 581.0
PYH1_k127_2952870_0 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000495 255.0
PYH1_k127_2952870_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001339 252.0
PYH1_k127_2952870_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000001994 225.0
PYH1_k127_3030354_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 474.0
PYH1_k127_3030354_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005366 256.0
PYH1_k127_3030354_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K12132 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.11.1,5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000005251 216.0
PYH1_k127_3030354_3 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000002555 124.0
PYH1_k127_3048291_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.903e-268 842.0
PYH1_k127_3048291_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 527.0
PYH1_k127_3049050_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.338e-239 744.0
PYH1_k127_3049050_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 277.0
PYH1_k127_3049050_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000002836 118.0
PYH1_k127_3054143_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005949 238.0
PYH1_k127_3054143_1 Flavodoxin-like fold - - - 0.0000229 48.0
PYH1_k127_3058731_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 558.0
PYH1_k127_3058731_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000002415 213.0
PYH1_k127_3058731_2 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000009344 125.0
PYH1_k127_3067085_0 HMGL-like K02594 - 2.3.3.14 9.913e-200 629.0
PYH1_k127_3067085_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 533.0
PYH1_k127_3067085_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 510.0
PYH1_k127_3067085_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
PYH1_k127_3067085_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000004429 246.0
PYH1_k127_3074517_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 368.0
PYH1_k127_3074517_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 347.0
PYH1_k127_3074517_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 332.0
PYH1_k127_3074517_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000001029 250.0
PYH1_k127_3074517_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
PYH1_k127_3074517_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000009077 193.0
PYH1_k127_3096719_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 353.0
PYH1_k127_3096719_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 340.0
PYH1_k127_3119426_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.151e-260 810.0
PYH1_k127_3119426_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.356e-214 671.0
PYH1_k127_3119426_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 547.0
PYH1_k127_3119426_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 517.0
PYH1_k127_3119426_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
PYH1_k127_3119426_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 467.0
PYH1_k127_3119426_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 301.0
PYH1_k127_3119426_7 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 305.0
PYH1_k127_3125631_0 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 319.0
PYH1_k127_3125631_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002903 265.0
PYH1_k127_3125631_2 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000001352 143.0
PYH1_k127_3192356_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 513.0
PYH1_k127_3192356_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 498.0
PYH1_k127_3192356_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000001445 51.0
PYH1_k127_3222522_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 394.0
PYH1_k127_3222740_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 404.0
PYH1_k127_3222740_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 348.0
PYH1_k127_3227065_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 481.0
PYH1_k127_3249219_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 492.0
PYH1_k127_3273367_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 364.0
PYH1_k127_3273367_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000001994 243.0
PYH1_k127_3273367_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000001588 134.0
PYH1_k127_3273367_3 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000003161 134.0
PYH1_k127_328364_0 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000008439 210.0
PYH1_k127_328364_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000001197 205.0
PYH1_k127_3323406_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000004729 150.0
PYH1_k127_3323406_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.00000006719 64.0
PYH1_k127_3328962_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 569.0
PYH1_k127_3328962_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 400.0
PYH1_k127_3328962_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000006065 209.0
PYH1_k127_335607_0 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000006371 128.0
PYH1_k127_335607_1 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000002533 83.0
PYH1_k127_3460472_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 576.0
PYH1_k127_3460472_1 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 422.0
PYH1_k127_3460472_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 376.0
PYH1_k127_3460472_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000002928 205.0
PYH1_k127_3460472_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000004292 190.0
PYH1_k127_3460472_5 - - - - 0.0006968 44.0
PYH1_k127_3493231_0 IPT/TIG domain - - - 0.000000000000000000000000000000000000000002408 162.0
PYH1_k127_3533976_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 287.0
PYH1_k127_3533976_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000005007 211.0
PYH1_k127_3533976_2 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.00000000000000000000000000000000000000000000000000004246 201.0
PYH1_k127_3533976_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000009337 190.0
PYH1_k127_3533976_4 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.00001147 49.0
PYH1_k127_3542412_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 458.0
PYH1_k127_3542412_1 - - - - 0.00000000000269 69.0
PYH1_k127_3542412_2 - - - - 0.000000002739 59.0
PYH1_k127_3589251_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 488.0
PYH1_k127_3589251_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001231 235.0
PYH1_k127_3608931_0 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000005873 202.0
PYH1_k127_3608931_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000002542 175.0
PYH1_k127_3618481_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 372.0
PYH1_k127_3620721_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 497.0
PYH1_k127_3620721_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 316.0
PYH1_k127_3620721_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000008281 125.0
PYH1_k127_3620721_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000001849 109.0
PYH1_k127_3622960_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 455.0
PYH1_k127_3622960_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 423.0
PYH1_k127_3622960_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 299.0
PYH1_k127_3633846_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
PYH1_k127_3633846_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
PYH1_k127_3633846_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000964 214.0
PYH1_k127_3633846_3 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.000000000000000000000000000000000000000008682 154.0
PYH1_k127_3633846_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000001197 145.0
PYH1_k127_3633846_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000002144 135.0
PYH1_k127_3633846_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000105 77.0
PYH1_k127_3633846_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003068 51.0
PYH1_k127_3648828_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1159.0
PYH1_k127_3648828_1 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000295 181.0
PYH1_k127_3648828_2 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000001313 123.0
PYH1_k127_3648828_3 - - - - 0.0000000000000000000000009478 114.0
PYH1_k127_3648828_4 Methyltransferase type 11 - - - 0.0000000000000001254 87.0
PYH1_k127_3648828_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000001016 66.0
PYH1_k127_3648828_6 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000003092 62.0
PYH1_k127_3648828_8 methyltransferase K16648 - - 0.0004732 49.0
PYH1_k127_3654657_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.071e-213 672.0
PYH1_k127_3654657_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000003519 136.0
PYH1_k127_3654657_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000001603 80.0
PYH1_k127_3654657_3 dolichyl monophosphate biosynthetic process - - - 0.0000000007173 67.0
PYH1_k127_3654815_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.262e-291 911.0
PYH1_k127_3659109_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 554.0
PYH1_k127_3659109_1 FAD dependent oxidoreductase K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 525.0
PYH1_k127_3659109_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 355.0
PYH1_k127_3659109_3 Short C-terminal domain K08982 - - 0.00004516 48.0
PYH1_k127_3659711_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 584.0
PYH1_k127_3659711_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 569.0
PYH1_k127_3659711_2 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.0000000000000000000002646 107.0
PYH1_k127_3678215_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 523.0
PYH1_k127_3678215_1 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 393.0
PYH1_k127_3678215_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000001141 75.0
PYH1_k127_3704362_0 Ftsk_gamma K03466 - - 3.652e-235 749.0
PYH1_k127_3704362_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.6e-217 683.0
PYH1_k127_3718566_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 605.0
PYH1_k127_3718566_1 spore germination K03605 - - 0.0000000000000000000000000000000005955 136.0
PYH1_k127_3728484_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 8.916e-262 818.0
PYH1_k127_3728484_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 433.0
PYH1_k127_3728484_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000003396 119.0
PYH1_k127_3728484_3 - - - - 0.000108 48.0
PYH1_k127_3740125_0 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 375.0
PYH1_k127_3740125_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
PYH1_k127_3740125_2 DNA modification repair radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001156 260.0
PYH1_k127_3744580_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 539.0
PYH1_k127_3744580_1 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.00000000000000000000000000005573 119.0
PYH1_k127_3764472_0 Endoribonuclease that initiates mRNA decay K18682 - - 4.24e-209 661.0
PYH1_k127_3764472_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 492.0
PYH1_k127_3764472_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 323.0
PYH1_k127_3764472_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 335.0
PYH1_k127_3764472_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
PYH1_k127_3764472_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
PYH1_k127_3764472_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000005863 205.0
PYH1_k127_3764472_7 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000539 177.0
PYH1_k127_3764472_8 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000002137 105.0
PYH1_k127_3764472_9 - - - - 0.000000001683 65.0
PYH1_k127_3777040_0 Arylsulfotransferase (ASST) - - - 4.12e-219 689.0
PYH1_k127_3777040_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 533.0
PYH1_k127_3777040_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 319.0
PYH1_k127_3777040_3 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000002957 203.0
PYH1_k127_380650_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000006299 182.0
PYH1_k127_380650_1 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000488 147.0
PYH1_k127_3812323_0 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 590.0
PYH1_k127_3812323_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 539.0
PYH1_k127_3820572_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 437.0
PYH1_k127_3828626_0 endonuclease III - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
PYH1_k127_3828626_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000001726 86.0
PYH1_k127_3828626_2 Amidohydrolase K07045 - - 0.00000005966 62.0
PYH1_k127_3834751_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.392e-262 832.0
PYH1_k127_3838898_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1362.0
PYH1_k127_3857001_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 362.0
PYH1_k127_3864880_0 peptidase, M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001092 253.0
PYH1_k127_3864880_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000126 205.0
PYH1_k127_3864880_2 Arylsulfotransferase (ASST) - - - 0.00000000000000522 78.0
PYH1_k127_3877921_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 447.0
PYH1_k127_3877921_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 422.0
PYH1_k127_3877921_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 358.0
PYH1_k127_3877921_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 321.0
PYH1_k127_3877921_4 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000001092 164.0
PYH1_k127_3877921_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001097 142.0
PYH1_k127_3877921_6 phosphoribosyltransferase K07100 - - 0.000000004176 60.0
PYH1_k127_389309_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000001171 231.0
PYH1_k127_389309_1 4Fe-4S binding domain K02572,K02573,K02574,K03616 - - 0.000000000000000000000000000000000000000000000000009674 196.0
PYH1_k127_3918879_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 278.0
PYH1_k127_3918879_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000006172 245.0
PYH1_k127_3918879_2 PFAM Fibronectin type III domain - - - 0.0000196 58.0
PYH1_k127_3918879_3 TIGRFAM cytochrome C family protein - - - 0.0005365 53.0
PYH1_k127_3942874_0 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 586.0
PYH1_k127_3942874_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 543.0
PYH1_k127_3942874_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001246 230.0
PYH1_k127_3942874_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000001897 162.0
PYH1_k127_3942874_4 Putative Fe-S cluster - - - 0.00000000000000000000211 100.0
PYH1_k127_3951590_0 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 317.0
PYH1_k127_3951590_1 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
PYH1_k127_3951590_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000004918 188.0
PYH1_k127_3951590_3 - K03975 - - 0.0000000000000000000000000000004955 130.0
PYH1_k127_3953612_0 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000003398 154.0
PYH1_k127_3957336_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
PYH1_k127_3957336_1 Stress-responsive transcriptional regulator K03973 - - 0.00000000000000001483 88.0
PYH1_k127_3957336_2 - - - - 0.000000000002032 78.0
PYH1_k127_3962280_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000008623 228.0
PYH1_k127_4005007_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 494.0
PYH1_k127_4005007_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 423.0
PYH1_k127_4005007_2 nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000001174 83.0
PYH1_k127_400642_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.271e-201 637.0
PYH1_k127_400642_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 443.0
PYH1_k127_400642_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000009751 261.0
PYH1_k127_400642_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000233 223.0
PYH1_k127_4014276_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 343.0
PYH1_k127_4014276_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 309.0
PYH1_k127_4014276_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 295.0
PYH1_k127_4014276_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
PYH1_k127_4014276_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000001342 170.0
PYH1_k127_4014276_5 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000003095 140.0
PYH1_k127_4014276_6 Lrp/AsnC ligand binding domain - - - 0.000000000000000000007743 94.0
PYH1_k127_4046582_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 439.0
PYH1_k127_4046582_1 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 291.0
PYH1_k127_4046582_2 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.0000000000000000000000000000000000001615 146.0
PYH1_k127_4053358_0 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 345.0
PYH1_k127_408023_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000001679 175.0
PYH1_k127_408023_1 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000001271 141.0
PYH1_k127_408023_2 Cupin domain - - - 0.00000000000001197 79.0
PYH1_k127_4096934_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 541.0
PYH1_k127_4096934_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000005139 204.0
PYH1_k127_4096934_2 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000002474 151.0
PYH1_k127_4096934_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000002456 81.0
PYH1_k127_4096934_4 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000004616 83.0
PYH1_k127_4108107_0 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 285.0
PYH1_k127_4108107_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001015 185.0
PYH1_k127_4126709_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 446.0
PYH1_k127_4126709_1 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 351.0
PYH1_k127_4126709_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000001148 195.0
PYH1_k127_4126709_3 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000001491 86.0
PYH1_k127_4142715_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000263 256.0
PYH1_k127_4145755_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 373.0
PYH1_k127_4145755_2 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000006003 71.0
PYH1_k127_4155976_0 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000003343 162.0
PYH1_k127_4155976_1 DegV family - - - 0.0000000001627 66.0
PYH1_k127_4155976_2 Extracellular liganD-binding receptor K01999 - - 0.000003842 59.0
PYH1_k127_4167199_0 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 306.0
PYH1_k127_4167199_1 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 302.0
PYH1_k127_4167199_2 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.00000000000000000000000000000000000000000001665 176.0
PYH1_k127_4167199_3 PFAM Integrase core domain - - - 0.000000171 63.0
PYH1_k127_4171700_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 561.0
PYH1_k127_4171700_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
PYH1_k127_4171700_2 Replication initiation and membrane attachment - - - 0.0000000000000000000000000000000000000000000000001121 187.0
PYH1_k127_4171700_3 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000005247 128.0
PYH1_k127_4171700_4 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000005034 84.0
PYH1_k127_4205886_0 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
PYH1_k127_4205886_1 - - - - 0.000000000000000000000000000000000000000000000000001182 194.0
PYH1_k127_4205886_2 PAC2 family - - - 0.000000000000000000000000000000000000000005806 166.0
PYH1_k127_4236804_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 344.0
PYH1_k127_4236804_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000007373 89.0
PYH1_k127_4275905_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K07469,K11177 - 1.17.1.4,1.2.5.3,1.2.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 468.0
PYH1_k127_4296763_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
PYH1_k127_4296763_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000004554 211.0
PYH1_k127_4360304_0 tRNA-splicing ligase RtcB K14415 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 505.0
PYH1_k127_4360304_1 Cell division protein FtsJ - - - 0.00000000000000005617 84.0
PYH1_k127_4360304_2 - - - - 0.00000000001113 70.0
PYH1_k127_4360304_3 Protein of unknown function DUF45 K07043 - - 0.00000005209 63.0
PYH1_k127_4375688_0 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 286.0
PYH1_k127_4375688_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 260.0
PYH1_k127_438305_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000008537 185.0
PYH1_k127_4390129_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.889e-232 732.0
PYH1_k127_4390129_1 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002198 244.0
PYH1_k127_4390129_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000002809 248.0
PYH1_k127_4390129_3 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000005564 236.0
PYH1_k127_4390129_4 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000005346 155.0
PYH1_k127_4390129_5 PQ loop repeat K15383 - - 0.00000000000002526 75.0
PYH1_k127_4418355_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 328.0
PYH1_k127_4418355_1 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000007834 217.0
PYH1_k127_4418355_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000005134 159.0
PYH1_k127_4418355_3 4Fe-4S dicluster domain - - - 0.00000000000000000004951 91.0
PYH1_k127_4419999_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 464.0
PYH1_k127_4419999_1 Psort location Cytoplasmic, score - - - 0.0000000000001022 73.0
PYH1_k127_4419999_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000419 49.0
PYH1_k127_447436_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 373.0
PYH1_k127_447436_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 334.0
PYH1_k127_447436_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 321.0
PYH1_k127_451880_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.564e-304 955.0
PYH1_k127_452222_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 433.0
PYH1_k127_452222_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K20445 - 1.17.1.5 0.00000000000000000000000004797 113.0
PYH1_k127_4579268_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1546.0
PYH1_k127_4579268_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.496e-257 810.0
PYH1_k127_4579268_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000002296 118.0
PYH1_k127_4579268_11 PFAM response regulator receiver - - - 0.0000000000000000000004586 100.0
PYH1_k127_4579268_12 PFAM Cyclic nucleotide-binding domain - - - 0.00000002877 61.0
PYH1_k127_4579268_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.781e-197 624.0
PYH1_k127_4579268_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 400.0
PYH1_k127_4579268_4 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 314.0
PYH1_k127_4579268_5 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 306.0
PYH1_k127_4579268_6 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002796 276.0
PYH1_k127_4579268_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000135 215.0
PYH1_k127_4579268_8 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000007244 189.0
PYH1_k127_4579268_9 GAF domain - - - 0.0000000000000000000000000000000000000000000000007997 190.0
PYH1_k127_4597725_0 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 323.0
PYH1_k127_4597725_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000007103 169.0
PYH1_k127_4597725_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000001383 163.0
PYH1_k127_4597725_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000008081 134.0
PYH1_k127_4597725_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000005419 66.0
PYH1_k127_459946_0 Alpha amylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 301.0
PYH1_k127_459946_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000002425 206.0
PYH1_k127_460545_0 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000005832 238.0
PYH1_k127_460545_1 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.0000000000000000000000002092 115.0
PYH1_k127_4613536_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.0000000000000000000000000000000000000000000001761 181.0
PYH1_k127_4613536_1 chain release factor K15034 - - 0.000000000000000000003443 95.0
PYH1_k127_4636625_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.953e-209 665.0
PYH1_k127_4636625_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 574.0
PYH1_k127_4636625_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 353.0
PYH1_k127_4636625_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
PYH1_k127_4636625_4 acylphosphatase activity K01512 - 3.6.1.7 0.0000000000000000001617 91.0
PYH1_k127_466458_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
PYH1_k127_4665128_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 562.0
PYH1_k127_4665128_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 534.0
PYH1_k127_4665128_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 330.0
PYH1_k127_4665128_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
PYH1_k127_4665128_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
PYH1_k127_4665128_5 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000001157 172.0
PYH1_k127_4665128_6 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001152 93.0
PYH1_k127_466828_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 603.0
PYH1_k127_466828_1 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000001067 177.0
PYH1_k127_466828_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000004007 119.0
PYH1_k127_4680043_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 536.0
PYH1_k127_4680043_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000004584 166.0
PYH1_k127_4680043_2 Dolichol kinase - - - 0.0001568 48.0
PYH1_k127_4699283_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1049.0
PYH1_k127_4699283_1 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 307.0
PYH1_k127_4699283_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 299.0
PYH1_k127_4699283_3 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000002834 207.0
PYH1_k127_4699283_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000002704 156.0
PYH1_k127_4699283_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000004449 138.0
PYH1_k127_4699283_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000001474 119.0
PYH1_k127_4699283_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000001893 111.0
PYH1_k127_4699283_8 PFAM Major Facilitator Superfamily - - - 0.000000000000000000002545 107.0
PYH1_k127_4699283_9 AraC-like ligand binding domain - - - 0.000000000000009918 79.0
PYH1_k127_4714334_0 - - - - 0.000000000000000000000000000000000000000000000000002876 197.0
PYH1_k127_4714334_1 Peptidase MA superfamily - - - 0.00000000001914 68.0
PYH1_k127_4715373_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000002213 256.0
PYH1_k127_4729667_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 473.0
PYH1_k127_4729667_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 306.0
PYH1_k127_4729667_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000004008 185.0
PYH1_k127_4730363_0 Dak1_2 K07030 - - 1.361e-204 650.0
PYH1_k127_4730363_1 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 566.0
PYH1_k127_4730363_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 350.0
PYH1_k127_4730363_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 335.0
PYH1_k127_4730363_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003506 264.0
PYH1_k127_4730363_5 Ribosomal L28 family K02902 - - 0.00000000000000000004572 92.0
PYH1_k127_4752774_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 319.0
PYH1_k127_4752774_1 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000004391 201.0
PYH1_k127_4752774_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000007221 142.0
PYH1_k127_4752774_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000002727 105.0
PYH1_k127_4752774_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00002852 48.0
PYH1_k127_4762981_0 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 450.0
PYH1_k127_4762981_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000005572 196.0
PYH1_k127_4762981_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000007625 139.0
PYH1_k127_476332_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
PYH1_k127_476332_1 ABC-2 family transporter protein - - - 0.00000000000000000000004798 109.0
PYH1_k127_476332_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000232 67.0
PYH1_k127_4765453_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.167e-219 703.0
PYH1_k127_479136_0 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000001811 154.0
PYH1_k127_479136_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000002285 82.0
PYH1_k127_4793488_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 321.0
PYH1_k127_4793488_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
PYH1_k127_4793488_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
PYH1_k127_4793488_3 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000002484 183.0
PYH1_k127_4793488_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000006404 112.0
PYH1_k127_4793488_5 DAK2 domain fusion protein YloV K07030 - - 0.0000000000007206 70.0
PYH1_k127_4793488_6 ATP binding cassette transporter ABC protein K01990 - - 0.0002646 46.0
PYH1_k127_4802508_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
PYH1_k127_4802508_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000003375 117.0
PYH1_k127_4811351_0 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000009957 188.0
PYH1_k127_4819258_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 307.0
PYH1_k127_4819258_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000515 220.0
PYH1_k127_4864502_0 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
PYH1_k127_4864502_1 cyclase family - - - 0.00000000000000000000000000000000000000000000000000000005024 206.0
PYH1_k127_4864502_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000002518 188.0
PYH1_k127_4864502_3 cyclase family - - - 0.000000000000000000000000000000000000000000000004202 182.0
PYH1_k127_4864502_4 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000004207 49.0
PYH1_k127_4896150_0 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000001633 214.0
PYH1_k127_4896150_1 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000001781 188.0
PYH1_k127_4896150_2 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000008841 147.0
PYH1_k127_4905444_0 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 376.0
PYH1_k127_4905444_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000001067 238.0
PYH1_k127_4905444_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000001487 116.0
PYH1_k127_4934858_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 398.0
PYH1_k127_4957898_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 586.0
PYH1_k127_4957898_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 282.0
PYH1_k127_4957898_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000001147 114.0
PYH1_k127_4957898_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000003444 97.0
PYH1_k127_4957898_4 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00005418 46.0
PYH1_k127_4966234_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 568.0
PYH1_k127_4966234_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 447.0
PYH1_k127_4966234_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006005 273.0
PYH1_k127_4983101_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000001462 163.0
PYH1_k127_5005642_0 Trehalase - - - 0.00000000000000000000000000000002048 136.0
PYH1_k127_5005642_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000005092 121.0
PYH1_k127_5048251_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 399.0
PYH1_k127_5063617_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
PYH1_k127_5063617_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000139 259.0
PYH1_k127_5063617_10 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001481 94.0
PYH1_k127_5063617_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000001188 83.0
PYH1_k127_5063617_12 structural constituent of ribosome K02904 - - 0.000000000000002177 79.0
PYH1_k127_5063617_2 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000228 210.0
PYH1_k127_5063617_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000001213 203.0
PYH1_k127_5063617_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000004369 184.0
PYH1_k127_5063617_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000001772 179.0
PYH1_k127_5063617_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000006297 153.0
PYH1_k127_5063617_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000001247 149.0
PYH1_k127_5063617_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007691 103.0
PYH1_k127_5063617_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000003541 98.0
PYH1_k127_507971_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000001036 217.0
PYH1_k127_509189_0 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 541.0
PYH1_k127_509189_1 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000002247 53.0
PYH1_k127_5172968_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 544.0
PYH1_k127_5172968_1 PHP domain K07053 - 3.1.3.97 0.000000000000000000000006484 107.0
PYH1_k127_5187257_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 574.0
PYH1_k127_5187257_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000002621 164.0
PYH1_k127_5187257_2 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.0000000000000000000000001731 109.0
PYH1_k127_5187518_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000003864 213.0
PYH1_k127_5187518_1 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000002045 194.0
PYH1_k127_5188563_0 LysE type translocator - - - 0.0000000000000000000000000000000000000000002078 164.0
PYH1_k127_5281757_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001295 250.0
PYH1_k127_5281757_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000002101 156.0
PYH1_k127_532602_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 375.0
PYH1_k127_532602_1 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000001099 185.0
PYH1_k127_532602_2 - - - - 0.0000002148 59.0
PYH1_k127_5349519_0 TIGRFAM Translation elongation factor K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 290.0
PYH1_k127_5349519_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000008677 253.0
PYH1_k127_5395966_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000001109 250.0
PYH1_k127_5395966_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
PYH1_k127_5396472_0 NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 377.0
PYH1_k127_5396472_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 331.0
PYH1_k127_5396472_2 MmgE/PrpD family - - - 0.0000000000000000000000001208 121.0
PYH1_k127_5429271_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 310.0
PYH1_k127_5429271_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000001591 164.0
PYH1_k127_5429271_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000004813 163.0
PYH1_k127_543238_0 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000005368 229.0
PYH1_k127_543238_1 Cytidylate kinase-like family - - - 0.00000000000002943 76.0
PYH1_k127_5437644_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.646e-300 931.0
PYH1_k127_5437644_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 541.0
PYH1_k127_5437644_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 462.0
PYH1_k127_5437644_3 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 419.0
PYH1_k127_5437644_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 365.0
PYH1_k127_5437644_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 271.0
PYH1_k127_5437644_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000001228 223.0
PYH1_k127_5437644_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000302 177.0
PYH1_k127_5437644_8 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000001001 149.0
PYH1_k127_5437644_9 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000005513 134.0
PYH1_k127_5458330_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 368.0
PYH1_k127_5458330_1 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001845 259.0
PYH1_k127_5458330_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000004825 106.0
PYH1_k127_5475260_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 575.0
PYH1_k127_5475260_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000004086 105.0
PYH1_k127_5501167_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 497.0
PYH1_k127_5501167_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000008395 233.0
PYH1_k127_5501167_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000325 197.0
PYH1_k127_5513515_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 551.0
PYH1_k127_5513515_1 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002241 257.0
PYH1_k127_5513515_10 Metallopeptidase family M24 - - - 0.00000000002045 71.0
PYH1_k127_5513515_11 membrane - - - 0.0000002981 59.0
PYH1_k127_5513515_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001994 243.0
PYH1_k127_5513515_3 peptidase, M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002515 244.0
PYH1_k127_5513515_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000001638 242.0
PYH1_k127_5513515_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
PYH1_k127_5513515_6 oxidoreductase activity, acting on CH-OH group of donors K18337 - 1.1.1.173,1.1.1.377,1.1.1.378 0.000000000000000000000000000000000000000000000000000001779 201.0
PYH1_k127_5513515_7 Thioredoxin-like - - - 0.0000000000000000000000000003547 120.0
PYH1_k127_5513515_8 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000004356 102.0
PYH1_k127_5541061_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001057 276.0
PYH1_k127_5541061_1 MaoC like domain - - - 0.0000000000000000000000000000000000002615 145.0
PYH1_k127_5541061_2 response regulator - - - 0.0000000000000000000000003301 113.0
PYH1_k127_5541061_3 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000176 103.0
PYH1_k127_5564102_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 539.0
PYH1_k127_5564102_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00123,K00266 - 1.17.1.9,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 471.0
PYH1_k127_5564102_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 430.0
PYH1_k127_5564102_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 424.0
PYH1_k127_5564102_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
PYH1_k127_5564102_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000003412 157.0
PYH1_k127_5564102_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.000000000000000000000000000000001096 139.0
PYH1_k127_5564102_7 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000484 133.0
PYH1_k127_5564102_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000004087 111.0
PYH1_k127_5573608_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001111 253.0
PYH1_k127_5573608_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000006253 129.0
PYH1_k127_5595848_0 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000004048 222.0
PYH1_k127_5595848_1 integral membrane protein - - - 0.000000000000000007622 91.0
PYH1_k127_5644481_0 acid phosphatase activity - - - 0.00000000000000000000000000000000000007417 155.0
PYH1_k127_5644481_1 Arylsulfotransferase (ASST) - - - 0.00003487 47.0
PYH1_k127_5663518_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 419.0
PYH1_k127_5663518_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 415.0
PYH1_k127_5663518_2 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 282.0
PYH1_k127_5663518_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001886 279.0
PYH1_k127_5663518_4 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000001238 146.0
PYH1_k127_5664912_0 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 514.0
PYH1_k127_5664912_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 332.0
PYH1_k127_5664912_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000006798 197.0
PYH1_k127_5664912_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000123 177.0
PYH1_k127_5691615_0 TIGRFAM sodium ion-translocating decarboxylase, beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 450.0
PYH1_k127_5691615_1 Cytidylate kinase-like family - - - 0.00000000001843 69.0
PYH1_k127_5707631_0 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000413 280.0
PYH1_k127_5737384_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000149 209.0
PYH1_k127_5737384_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000002721 177.0
PYH1_k127_5737384_2 Stage II sporulation protein M K06384 - - 0.000000000000006922 82.0
PYH1_k127_5753034_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 502.0
PYH1_k127_5753034_1 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 361.0
PYH1_k127_5753034_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000002173 165.0
PYH1_k127_5753034_3 Bacterial extracellular solute-binding protein - - - 0.000000000000000000003628 104.0
PYH1_k127_5753034_4 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.00000000002823 74.0
PYH1_k127_5753160_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 548.0
PYH1_k127_5753160_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 364.0
PYH1_k127_5753160_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000289 156.0
PYH1_k127_5753160_3 PFAM Uncharacterised protein, DegV family COG1307 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002925 128.0
PYH1_k127_5804309_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 338.0
PYH1_k127_5804309_1 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.0000000000000001319 82.0
PYH1_k127_5818708_0 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000005344 116.0
PYH1_k127_5818708_1 TIGRFAM DNA polymerase LigD, polymerase domain protein K01971 - 6.5.1.1 0.0009165 42.0
PYH1_k127_5832607_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.308e-241 765.0
PYH1_k127_5832607_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 288.0
PYH1_k127_5832607_2 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000002691 229.0
PYH1_k127_5832607_3 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
PYH1_k127_5832607_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000994 133.0
PYH1_k127_5832607_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000006147 106.0
PYH1_k127_5832607_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000001724 74.0
PYH1_k127_5842270_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 495.0
PYH1_k127_5842270_1 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 484.0
PYH1_k127_5842270_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 445.0
PYH1_k127_5842270_3 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000032 246.0
PYH1_k127_5842270_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000002976 224.0
PYH1_k127_5842270_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000182 187.0
PYH1_k127_5842270_6 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000005557 195.0
PYH1_k127_5842270_7 denitrification pathway - - - 0.000000000000000000000000000000000000000000000003493 182.0
PYH1_k127_5842270_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001823 165.0
PYH1_k127_5842270_9 methionine transport K02071 - - 0.0000000000000002594 81.0
PYH1_k127_5842939_0 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
PYH1_k127_5842939_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000008491 171.0
PYH1_k127_5852373_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.197e-236 741.0
PYH1_k127_5852373_1 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 348.0
PYH1_k127_5852373_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000123 120.0
PYH1_k127_5852373_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000001916 113.0
PYH1_k127_5852373_12 Binds the 23S rRNA K02909 - - 0.00000000000000000000000007414 107.0
PYH1_k127_5852373_13 - - - - 0.00000000000000002059 84.0
PYH1_k127_5852373_2 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 297.0
PYH1_k127_5852373_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001728 254.0
PYH1_k127_5852373_4 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000009957 222.0
PYH1_k127_5852373_5 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
PYH1_k127_5852373_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000004968 176.0
PYH1_k127_5852373_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000003538 168.0
PYH1_k127_5852373_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000489 155.0
PYH1_k127_5852373_9 PFAM glutaredoxin - - - 0.00000000000000000000000000006045 121.0
PYH1_k127_5854844_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 337.0
PYH1_k127_5854844_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000005727 72.0
PYH1_k127_5859465_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 2.675e-210 664.0
PYH1_k127_5859465_1 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 296.0
PYH1_k127_5872423_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.237e-289 898.0
PYH1_k127_5872423_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 530.0
PYH1_k127_5872423_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
PYH1_k127_5872423_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000006529 230.0
PYH1_k127_5872423_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000003491 217.0
PYH1_k127_5872423_5 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000435 215.0
PYH1_k127_5875529_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 459.0
PYH1_k127_5875529_1 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000004629 165.0
PYH1_k127_5875529_2 - - - - 0.0000000001623 62.0
PYH1_k127_5875529_3 PFAM Nitrate reductase gamma subunit - - - 0.000000001652 62.0
PYH1_k127_5894958_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 480.0
PYH1_k127_5898813_0 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000005491 213.0
PYH1_k127_5898813_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000001719 155.0
PYH1_k127_5946484_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 290.0
PYH1_k127_5946484_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 292.0
PYH1_k127_5946484_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
PYH1_k127_5946484_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000003083 192.0
PYH1_k127_5946484_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000004476 178.0
PYH1_k127_5946484_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000000000001841 173.0
PYH1_k127_5946484_6 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000157 174.0
PYH1_k127_5946484_7 Thioesterase superfamily - - - 0.00000000000000000000000741 114.0
PYH1_k127_5946484_8 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00004649 48.0
PYH1_k127_5956447_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.306e-310 958.0
PYH1_k127_5956447_1 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 310.0
PYH1_k127_5956447_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
PYH1_k127_5956447_3 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 296.0
PYH1_k127_5956447_4 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000009189 170.0
PYH1_k127_5980312_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 632.0
PYH1_k127_5980312_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 557.0
PYH1_k127_5980312_2 ligase activity K01474 - 3.5.2.14 0.00000000000000000000000826 117.0
PYH1_k127_5980312_3 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000001204 60.0
PYH1_k127_5980312_4 Creatinase/Prolidase N-terminal domain - - - 0.00003134 48.0
PYH1_k127_5982836_0 - - - - 0.000000000000000000003389 110.0
PYH1_k127_5982836_1 TIGRFAM RHS repeat-associated core domain-containing protein, YD repeat protein - - - 0.000000000000001465 90.0
PYH1_k127_5985823_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 544.0
PYH1_k127_5985823_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000009591 259.0
PYH1_k127_5985823_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000001473 213.0
PYH1_k127_5985823_3 acetyltransferase - - - 0.000000000000000000000000000000000003519 143.0
PYH1_k127_6006669_0 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000000000000000000002274 182.0
PYH1_k127_6006669_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000005825 160.0
PYH1_k127_6006669_2 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000689 112.0
PYH1_k127_6006669_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000001982 79.0
PYH1_k127_6010827_0 Elongation factor G C-terminus K06207 - - 1.211e-264 828.0
PYH1_k127_6013579_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 244.0
PYH1_k127_6013579_1 acetyltransferase - - - 0.000000000000000000000000000000000000007102 153.0
PYH1_k127_6021248_0 Conserved region in glutamate synthase - - - 9.566e-254 791.0
PYH1_k127_6021248_1 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000001634 202.0
PYH1_k127_604106_0 - - - - 0.000000000000000007265 86.0
PYH1_k127_604845_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 389.0
PYH1_k127_604845_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 377.0
PYH1_k127_6056141_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 616.0
PYH1_k127_6056141_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 576.0
PYH1_k127_6056141_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 435.0
PYH1_k127_6056141_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000004187 244.0
PYH1_k127_6056141_4 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000007781 238.0
PYH1_k127_6059141_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.733e-318 997.0
PYH1_k127_6070824_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
PYH1_k127_6070824_1 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000008758 192.0
PYH1_k127_6070824_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000004751 131.0
PYH1_k127_6090000_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 295.0
PYH1_k127_6090000_1 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001273 214.0
PYH1_k127_6113251_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 607.0
PYH1_k127_6113251_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 286.0
PYH1_k127_6113251_2 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000002232 128.0
PYH1_k127_6113251_3 - - - - 0.0000000000000000611 81.0
PYH1_k127_6125793_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 326.0
PYH1_k127_6125793_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000003043 237.0
PYH1_k127_6195577_0 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000000000000000000000006025 223.0
PYH1_k127_6195577_1 NurA - - - 0.000000000000000000000000001284 117.0
PYH1_k127_6196295_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 604.0
PYH1_k127_6196295_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 473.0
PYH1_k127_6196295_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 368.0
PYH1_k127_6196295_3 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 351.0
PYH1_k127_6196295_4 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
PYH1_k127_6196295_5 NIL - - - 0.00000000000000000000000000000000000000000000000000000001254 200.0
PYH1_k127_6196295_6 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
PYH1_k127_6196295_7 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000001713 140.0
PYH1_k127_6196295_8 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000483 123.0
PYH1_k127_6199469_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 397.0
PYH1_k127_6199469_1 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000259 218.0
PYH1_k127_6199469_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000003238 162.0
PYH1_k127_6222992_0 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 298.0
PYH1_k127_6222992_1 Glutamine cyclotransferase K00683 - 2.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001421 260.0
PYH1_k127_6222992_2 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000009205 108.0
PYH1_k127_623623_0 Iron-sulfur cluster-binding protein K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 476.0
PYH1_k127_623623_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000002406 203.0
PYH1_k127_623623_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000916 150.0
PYH1_k127_6240215_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 360.0
PYH1_k127_6240215_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
PYH1_k127_6240215_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005547 254.0
PYH1_k127_6240215_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000242 194.0
PYH1_k127_6240215_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000167 183.0
PYH1_k127_6240215_5 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000001569 172.0
PYH1_k127_6240215_6 structural constituent of ribosome K02879 - - 0.0000000000000000000000000000000000000000002862 161.0
PYH1_k127_6240215_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000001209 156.0
PYH1_k127_6240215_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004507 153.0
PYH1_k127_6240648_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 383.0
PYH1_k127_6256162_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 2.593e-210 670.0
PYH1_k127_6256162_1 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 454.0
PYH1_k127_6256162_2 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 410.0
PYH1_k127_6256162_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000001416 52.0
PYH1_k127_6256162_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K15583 - - 0.00006547 45.0
PYH1_k127_631906_0 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 540.0
PYH1_k127_631906_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 427.0
PYH1_k127_631906_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 326.0
PYH1_k127_631906_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000003634 97.0
PYH1_k127_6349879_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 554.0
PYH1_k127_6349879_1 Selenocysteine-specific translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003218 271.0
PYH1_k127_6349879_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000002162 161.0
PYH1_k127_6385050_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 355.0
PYH1_k127_6385050_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003765 246.0
PYH1_k127_6385050_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000001256 150.0
PYH1_k127_6409585_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005894 243.0
PYH1_k127_6409585_1 Rhs family - - - 0.000417 49.0
PYH1_k127_6433270_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 392.0
PYH1_k127_6461458_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 536.0
PYH1_k127_6461458_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000002575 94.0
PYH1_k127_650035_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
PYH1_k127_650035_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002393 237.0
PYH1_k127_650035_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000001876 209.0
PYH1_k127_650035_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000005303 142.0
PYH1_k127_650035_4 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000000001965 134.0
PYH1_k127_6501053_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001269 233.0
PYH1_k127_6501053_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000146 199.0
PYH1_k127_6501053_2 peptidase U32 - - - 0.000000000000000000000000256 107.0
PYH1_k127_6501053_3 - - - - 0.00000000000004158 74.0
PYH1_k127_6514326_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 563.0
PYH1_k127_6517361_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 544.0
PYH1_k127_6517361_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000001073 68.0
PYH1_k127_6532053_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.167e-292 915.0
PYH1_k127_6579341_0 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000004461 87.0
PYH1_k127_6579341_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000001291 88.0
PYH1_k127_661269_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 316.0
PYH1_k127_661269_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000008051 109.0
PYH1_k127_6617569_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 5.855e-240 765.0
PYH1_k127_6617569_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.822e-239 750.0
PYH1_k127_6617569_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000008306 76.0
PYH1_k127_6617569_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 612.0
PYH1_k127_6617569_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 454.0
PYH1_k127_6617569_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 421.0
PYH1_k127_6617569_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 416.0
PYH1_k127_6617569_6 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 302.0
PYH1_k127_6617569_7 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
PYH1_k127_6617569_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000003584 208.0
PYH1_k127_6617569_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000001202 141.0
PYH1_k127_6703486_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.789e-273 851.0
PYH1_k127_6703486_1 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 569.0
PYH1_k127_6703486_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 502.0
PYH1_k127_6703486_3 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001596 232.0
PYH1_k127_6712565_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 1.69e-203 663.0
PYH1_k127_6712565_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000004469 164.0
PYH1_k127_671381_0 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 381.0
PYH1_k127_671381_1 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 298.0
PYH1_k127_671381_2 ABC transporter K02003 - - 0.000000000000000000000000000000001169 131.0
PYH1_k127_6727130_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 547.0
PYH1_k127_6744210_0 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 300.0
PYH1_k127_6748856_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005587 279.0
PYH1_k127_676358_0 Major Facilitator Superfamily - - - 0.00000000005638 73.0
PYH1_k127_6787684_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 7.48e-236 750.0
PYH1_k127_6787684_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000306 234.0
PYH1_k127_6787754_0 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000005541 187.0
PYH1_k127_6787754_1 - - - - 0.0000003557 59.0
PYH1_k127_6789332_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
PYH1_k127_6789332_1 MFS transporter - - - 0.00000000000000000000000000000003803 141.0
PYH1_k127_6809941_0 AMP-binding enzyme K01897 - 6.2.1.3 7.176e-296 918.0
PYH1_k127_6809941_1 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 6.838e-283 882.0
PYH1_k127_6809941_10 Thioesterase superfamily K02614 - - 0.0000000000000000000000000004593 118.0
PYH1_k127_6809941_11 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.000000000000000000001626 99.0
PYH1_k127_6809941_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.569e-209 668.0
PYH1_k127_6809941_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
PYH1_k127_6809941_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 462.0
PYH1_k127_6809941_5 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 454.0
PYH1_k127_6809941_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 376.0
PYH1_k127_6809941_7 PFAM Sodium calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001735 254.0
PYH1_k127_6809941_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000007854 175.0
PYH1_k127_6809941_9 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000002295 162.0
PYH1_k127_6849871_0 YHYH protein - - - 0.00000000000000000001422 100.0
PYH1_k127_6849871_1 - - - - 0.00000000000001639 74.0
PYH1_k127_6850315_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000002966 155.0
PYH1_k127_6891231_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 420.0
PYH1_k127_6891231_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000002205 208.0
PYH1_k127_6891231_2 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000000000009263 188.0
PYH1_k127_6891231_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000008557 155.0
PYH1_k127_6891231_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000004639 130.0
PYH1_k127_6891231_5 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.0000002119 61.0
PYH1_k127_6902966_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000001488 191.0
PYH1_k127_6912339_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 3.831e-194 628.0
PYH1_k127_6912339_1 PFAM ferredoxin-dependent glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 472.0
PYH1_k127_6912339_2 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 334.0
PYH1_k127_6912339_3 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474,K10854 - 3.5.2.14,6.4.1.6 0.00000000000000000000000000000000000000000000000000000000000000006069 231.0
PYH1_k127_6920111_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.733e-261 815.0
PYH1_k127_6920111_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 317.0
PYH1_k127_6920111_2 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 301.0
PYH1_k127_6920111_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008962 265.0
PYH1_k127_6920111_4 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.00000000000000000000000000000000000022 147.0
PYH1_k127_6922690_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 282.0
PYH1_k127_6922690_1 COG0006 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000003741 125.0
PYH1_k127_6922690_2 Pfam:DUF2424 K14731 - 3.1.1.83 0.000000000000000003233 89.0
PYH1_k127_6929565_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 392.0
PYH1_k127_6943041_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 584.0
PYH1_k127_694758_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004444 254.0
PYH1_k127_694758_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000006026 75.0
PYH1_k127_6979673_0 Domain of unknown function (DUF1998) K06877 - - 8.97e-288 902.0
PYH1_k127_6979673_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000004268 205.0
PYH1_k127_6979673_2 Protein of unknown function (DUF503) K09764 - - 0.000000009192 57.0
PYH1_k127_6982471_0 - - - - 0.0000000000000000000000000000000000000004382 149.0
PYH1_k127_7020126_0 PFAM formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.00000000000000000000000000000000000000000000000000006459 198.0
PYH1_k127_7020126_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000005584 87.0
PYH1_k127_7082902_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 462.0
PYH1_k127_7082902_1 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 432.0
PYH1_k127_7082902_2 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 398.0
PYH1_k127_7082902_3 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
PYH1_k127_7082902_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000003459 130.0
PYH1_k127_7086131_0 dephospho-CoA kinase activity - - - 0.0000000000000000001912 95.0
PYH1_k127_7086131_1 Hep Hag repeat protein - - - 0.000000000000002426 83.0
PYH1_k127_7086131_2 Glycosyl hydrolases family 25 K07273 - - 0.0000000003003 71.0
PYH1_k127_7086131_3 DNA N-6-adenine-methyltransferase (Dam) - - - 0.000000003807 64.0
PYH1_k127_7086131_4 Putative peptidoglycan binding domain - - - 0.00007341 54.0
PYH1_k127_709243_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 359.0
PYH1_k127_709243_1 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000285 138.0
PYH1_k127_709243_2 Protein of unknown function (DUF1847) - - - 0.0000000000000000000002447 108.0
PYH1_k127_709243_3 - - - - 0.0000000000000000003485 93.0
PYH1_k127_709243_4 Protein of unknown function (DUF1847) - - - 0.0000000002899 61.0
PYH1_k127_7127692_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000002762 213.0
PYH1_k127_7171567_0 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K17735 - 1.1.1.108,1.1.1.157 0.00000000000000000000000000000000000000000000000000003254 199.0
PYH1_k127_7206088_0 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000001861 188.0
PYH1_k127_7218126_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.263e-201 634.0
PYH1_k127_7218126_1 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 298.0
PYH1_k127_7218126_2 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 301.0
PYH1_k127_7218126_3 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000002391 176.0
PYH1_k127_7218126_4 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000002932 148.0
PYH1_k127_7218126_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000007599 128.0
PYH1_k127_7218126_6 - - - - 0.000000000000000001078 85.0
PYH1_k127_7218126_7 TIGRFAM Ammonium transporter K03320 - - 0.0000000000004818 70.0
PYH1_k127_7231870_0 Ferritin-like domain K22336 - 1.16.3.1 0.0000000000000004877 81.0
PYH1_k127_7231870_1 Belongs to the ompA family K03640 - - 0.0001766 51.0
PYH1_k127_7235116_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 303.0
PYH1_k127_7235116_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000001721 224.0
PYH1_k127_7235116_2 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000004559 201.0
PYH1_k127_7235116_3 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000001131 165.0
PYH1_k127_7235116_4 Cyclophilin-like K09143 - - 0.000000000000000000000000000007962 122.0
PYH1_k127_728431_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
PYH1_k127_728431_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003857 284.0
PYH1_k127_728431_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000005689 124.0
PYH1_k127_728431_3 GYD domain - - - 0.0000000000000000000000005865 107.0
PYH1_k127_728431_4 - K04096 - - 0.00000000000000001726 86.0
PYH1_k127_728431_5 - - - - 0.00000000001395 68.0
PYH1_k127_7288410_0 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 599.0
PYH1_k127_7288410_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000009367 244.0
PYH1_k127_7288410_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000005873 187.0
PYH1_k127_7288410_3 TatD related DNase K03424 - - 0.00000000000000000000000000001092 130.0
PYH1_k127_730206_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.572e-260 820.0
PYH1_k127_730206_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 332.0
PYH1_k127_730206_2 YHYH protein - - - 0.0000000000000000000000000007356 121.0
PYH1_k127_730206_3 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000008052 116.0
PYH1_k127_730206_4 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000009634 75.0
PYH1_k127_7317439_0 cell redox homeostasis K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000007325 201.0
PYH1_k127_7317439_1 - - - - 0.00002032 48.0
PYH1_k127_7357059_0 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005506 254.0
PYH1_k127_7357059_1 Poly A polymerase head domain K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000001273 246.0
PYH1_k127_7357059_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
PYH1_k127_7357059_3 dUTPase K01520 - 3.6.1.23 0.0000000000000000000000000000000000001149 144.0
PYH1_k127_7378216_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 472.0
PYH1_k127_7378216_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 451.0
PYH1_k127_7378216_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
PYH1_k127_7378216_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000002804 218.0
PYH1_k127_7378216_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000003062 188.0
PYH1_k127_7378216_5 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000002071 176.0
PYH1_k127_7378216_6 Cysteinyl-tRNA synthetase K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000006677 167.0
PYH1_k127_7382564_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
PYH1_k127_7382564_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000001575 120.0
PYH1_k127_7382564_2 Uncharacterised ArCR, COG2043 - - - 0.00001304 49.0
PYH1_k127_7394123_0 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000004892 166.0
PYH1_k127_7394123_1 helix_turn_helix ASNC type K03718 - - 0.0000000000000002949 84.0
PYH1_k127_7398162_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.427e-205 647.0
PYH1_k127_7398162_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.009e-195 621.0
PYH1_k127_7398162_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 335.0
PYH1_k127_7404837_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 505.0
PYH1_k127_7404837_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 435.0
PYH1_k127_7404837_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
PYH1_k127_7404837_3 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 353.0
PYH1_k127_7404837_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000007648 205.0
PYH1_k127_7404837_5 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000002137 189.0
PYH1_k127_7412729_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.319e-234 747.0
PYH1_k127_7412729_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000001776 186.0
PYH1_k127_7412729_2 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.0000000000001255 72.0
PYH1_k127_7486530_0 COG0006 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000003528 195.0
PYH1_k127_7494439_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 504.0
PYH1_k127_7494439_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004255 158.0
PYH1_k127_7494439_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0003718 44.0
PYH1_k127_7502950_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000004316 183.0
PYH1_k127_7502950_1 PAC2 family K07159 - - 0.000000000000000000000000000001295 123.0
PYH1_k127_7503172_0 Dihydroxyacetone kinase family - - - 0.0000000000000000000000000000000000002189 153.0
PYH1_k127_7527818_0 4Fe-4S dicluster domain - - - 1.8e-257 800.0
PYH1_k127_7560446_0 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000008278 175.0
PYH1_k127_7606965_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 585.0
PYH1_k127_7612893_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 327.0
PYH1_k127_7612893_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000005293 219.0
PYH1_k127_7628475_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 439.0
PYH1_k127_7628475_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 430.0
PYH1_k127_7628475_10 - - - - 0.000000000000000000001007 95.0
PYH1_k127_7628475_11 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000001334 76.0
PYH1_k127_7628475_2 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
PYH1_k127_7628475_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 391.0
PYH1_k127_7628475_4 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 342.0
PYH1_k127_7628475_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 342.0
PYH1_k127_7628475_6 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005848 272.0
PYH1_k127_7628475_7 2-methylcitrate dehydratase activity K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000001991 193.0
PYH1_k127_7628475_8 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000009217 187.0
PYH1_k127_7628475_9 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000000001914 142.0
PYH1_k127_763325_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1381.0
PYH1_k127_763325_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000001178 76.0
PYH1_k127_7634266_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 344.0
PYH1_k127_7634266_1 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 292.0
PYH1_k127_7634266_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
PYH1_k127_7634266_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008307 259.0
PYH1_k127_7634266_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
PYH1_k127_7634266_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006507 227.0
PYH1_k127_7634266_6 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000006152 195.0
PYH1_k127_7634266_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000009219 115.0
PYH1_k127_7634266_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000002111 63.0
PYH1_k127_7648023_0 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000001319 160.0
PYH1_k127_7648023_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000001795 160.0
PYH1_k127_7648023_2 - - - - 0.00000000000000000000003688 102.0
PYH1_k127_769447_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 445.0
PYH1_k127_769447_1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000003115 181.0
PYH1_k127_769447_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000005686 177.0
PYH1_k127_7699535_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 292.0
PYH1_k127_7699535_1 ECF sigma factor K03088 - - 0.0000000000000000000000000003247 121.0
PYH1_k127_7699535_2 Tfp pilus assembly protein FimV - - - 0.00002038 57.0
PYH1_k127_770572_0 Winged helix-turn-helix - - - 0.0000000000000000000000000000000004998 135.0
PYH1_k127_770572_1 - - - - 0.000000000000000000000001566 106.0
PYH1_k127_7711276_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 289.0
PYH1_k127_7711276_1 acid phosphatase activity - - - 0.00000000000000000000002402 109.0
PYH1_k127_7727783_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.263e-211 664.0
PYH1_k127_7727783_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000513 250.0
PYH1_k127_7727783_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000171 186.0
PYH1_k127_7727783_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001245 127.0
PYH1_k127_7727783_4 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000263 112.0
PYH1_k127_7727783_5 Ribosomal protein S16 K02959 - - 0.0000000000000000000000001641 108.0
PYH1_k127_7727783_6 KH domain K06960 - - 0.00000000000000000000001706 101.0
PYH1_k127_7727783_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000003561 76.0
PYH1_k127_774865_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 503.0
PYH1_k127_77878_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000008953 211.0
PYH1_k127_77878_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000001864 87.0
PYH1_k127_7818361_0 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 310.0
PYH1_k127_7818361_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K03520 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000001822 218.0
PYH1_k127_7834518_0 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 341.0
PYH1_k127_7834518_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
PYH1_k127_7834518_2 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000006638 225.0
PYH1_k127_7834518_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000004954 177.0
PYH1_k127_7834518_4 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000002312 153.0
PYH1_k127_7834518_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000156 143.0
PYH1_k127_7834518_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002723 111.0
PYH1_k127_7834518_7 B12 binding domain - - - 0.00000000000000000005493 93.0
PYH1_k127_7834518_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000515 82.0
PYH1_k127_7847121_0 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000000000002683 231.0
PYH1_k127_7847121_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000006148 202.0
PYH1_k127_7847121_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000002119 136.0
PYH1_k127_7847121_3 - - - - 0.00000000000111 75.0
PYH1_k127_7866827_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000105 296.0
PYH1_k127_7866827_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K02003,K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000003332 218.0
PYH1_k127_7866827_2 HlyD family secretion protein K02005,K13888 - - 0.000000002106 69.0
PYH1_k127_7904708_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
PYH1_k127_7912736_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 9.743e-277 867.0
PYH1_k127_7930803_0 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 526.0
PYH1_k127_7957947_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000743 248.0
PYH1_k127_7957947_1 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000000000000000000000001242 188.0
PYH1_k127_7957947_2 COG0534 Na -driven multidrug efflux pump - - - 0.00000000000000000000000005457 113.0
PYH1_k127_7957947_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000007864 63.0
PYH1_k127_7978815_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.817e-212 668.0
PYH1_k127_7978815_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000002997 153.0
PYH1_k127_7978815_2 - - - - 0.0000000000000000000001778 104.0
PYH1_k127_798074_0 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 286.0
PYH1_k127_798074_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000002247 113.0
PYH1_k127_8011715_0 pathogenesis - - - 0.00000000000000006102 83.0
PYH1_k127_8011715_1 cellulase activity K12567 - 2.7.11.1 0.0000000000001964 79.0
PYH1_k127_8011715_2 Domain of unknown function (DUF4382) - - - 0.0000003616 55.0
PYH1_k127_8011715_3 Cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000002484 58.0
PYH1_k127_8021786_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 458.0
PYH1_k127_8021786_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 388.0
PYH1_k127_8021786_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
PYH1_k127_8021786_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000288 283.0
PYH1_k127_8021786_4 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
PYH1_k127_8021786_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000005426 70.0
PYH1_k127_8048007_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 316.0
PYH1_k127_8089523_0 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 345.0
PYH1_k127_8089523_1 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000001045 192.0
PYH1_k127_8089523_2 ABC-2 type transporter - - - 0.000000003279 61.0
PYH1_k127_8119556_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000008337 213.0
PYH1_k127_8119556_1 carotenoid biosynthetic process K10212 - - 0.00000000000000000000000000000007895 130.0
PYH1_k127_8173715_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 326.0
PYH1_k127_8173715_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 285.0
PYH1_k127_8173715_2 - - - - 0.000000000000000000000000000002771 121.0
PYH1_k127_8188831_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.723e-200 629.0
PYH1_k127_8188831_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 317.0
PYH1_k127_8188831_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000000837 132.0
PYH1_k127_8188831_3 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.000000000000003584 75.0
PYH1_k127_8188831_4 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000004509 76.0
PYH1_k127_8188831_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0008692 46.0
PYH1_k127_8192119_0 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000003402 158.0
PYH1_k127_8192119_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000009929 119.0
PYH1_k127_8192119_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000004238 108.0
PYH1_k127_8192119_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000003064 88.0
PYH1_k127_8192119_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000002727 76.0
PYH1_k127_8192119_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - 0.0000000001891 63.0
PYH1_k127_8240319_0 ABC transporter, transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 559.0
PYH1_k127_8240319_1 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 496.0
PYH1_k127_8240319_2 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 501.0
PYH1_k127_8240319_3 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 304.0
PYH1_k127_8240319_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008719 283.0
PYH1_k127_8240319_5 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000001736 171.0
PYH1_k127_8240319_6 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000001144 130.0
PYH1_k127_8240319_7 Protein of unknown function (DUF664) - - - 0.0000000000000001477 87.0
PYH1_k127_8245846_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 3.229e-213 676.0
PYH1_k127_8245846_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000001005 208.0
PYH1_k127_8245846_2 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000006428 157.0
PYH1_k127_8245846_3 Belongs to the 'phage' integrase family - - - 0.000000000000005762 75.0
PYH1_k127_8282835_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 303.0
PYH1_k127_8282835_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 256.0
PYH1_k127_8282835_11 COG NOG20805 non supervised orthologous group - - - 0.0003703 43.0
PYH1_k127_8282835_2 Alpha/beta hydrolase family K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000003988 216.0
PYH1_k127_8282835_3 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000000009599 117.0
PYH1_k127_8282835_4 the current gene model (or a revised gene model) may contain a premature stop - - - 0.00000000000000005742 80.0
PYH1_k127_8282835_6 Ribulose bisphosphate carboxylase, large chain K01601,K01963 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.1.3.15,4.1.1.39,6.4.1.2 0.000000003151 59.0
PYH1_k127_8282835_8 - - - - 0.0000003388 51.0
PYH1_k127_8282835_9 ORF located using Blastx - - - 0.0000817 47.0
PYH1_k127_8294061_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002687 241.0
PYH1_k127_8294061_1 Thioredoxin - - - 0.00000000000000000000000002861 116.0
PYH1_k127_8297411_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 315.0
PYH1_k127_8301757_0 PFAM PEBP family protein K06910 - - 0.00000002552 64.0
PYH1_k127_8302792_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 387.0
PYH1_k127_8302792_1 Subtilase family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000009121 182.0
PYH1_k127_8304630_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 436.0
PYH1_k127_8304630_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 426.0
PYH1_k127_8304630_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
PYH1_k127_8304630_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 292.0
PYH1_k127_8304630_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000002763 166.0
PYH1_k127_8304630_5 - - - - 0.0000000000000006226 83.0
PYH1_k127_8305068_0 ATPase AAA-2 domain protein K03696 - - 0.0 1050.0
PYH1_k127_8305068_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 492.0
PYH1_k127_8305068_10 CTP synthase K01937 - 6.3.4.2 0.0000000000001523 74.0
PYH1_k127_8305068_11 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.000000000007981 68.0
PYH1_k127_8305068_12 - - - - 0.00000000002238 65.0
PYH1_k127_8305068_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 416.0
PYH1_k127_8305068_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 390.0
PYH1_k127_8305068_4 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 366.0
PYH1_k127_8305068_5 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 315.0
PYH1_k127_8305068_6 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002769 259.0
PYH1_k127_8305068_7 Glutamine amidotransferase class-I - - - 0.0000000000000000000000001702 111.0
PYH1_k127_8305068_8 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000003311 83.0
PYH1_k127_8305068_9 Putative regulatory protein - - - 0.0000000000000004526 81.0
PYH1_k127_8305962_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 326.0
PYH1_k127_8305962_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 323.0
PYH1_k127_8305962_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000002022 241.0
PYH1_k127_8311029_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 2.37e-226 726.0
PYH1_k127_8311029_1 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 3.769e-208 660.0
PYH1_k127_8311029_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 548.0
PYH1_k127_8311029_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 413.0
PYH1_k127_8311029_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 404.0
PYH1_k127_8311029_5 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
PYH1_k127_8311029_6 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
PYH1_k127_8311029_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000008425 72.0
PYH1_k127_8315003_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 461.0
PYH1_k127_8315003_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 384.0
PYH1_k127_8315003_10 - - - - 0.000000000000000000000000000000000000000000000001026 177.0
PYH1_k127_8315003_11 Regulatory protein, FmdB family - - - 0.0000000005948 63.0
PYH1_k127_8315003_12 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00001286 54.0
PYH1_k127_8315003_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 366.0
PYH1_k127_8315003_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 363.0
PYH1_k127_8315003_4 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 331.0
PYH1_k127_8315003_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 308.0
PYH1_k127_8315003_6 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 274.0
PYH1_k127_8315003_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000007548 261.0
PYH1_k127_8315003_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000002229 214.0
PYH1_k127_8315003_9 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000001362 212.0
PYH1_k127_8334341_0 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 371.0
PYH1_k127_8334341_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0004591 45.0
PYH1_k127_8334757_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001295 244.0
PYH1_k127_8334757_1 response regulator - - - 0.0000000000000000000000001364 109.0
PYH1_k127_8337486_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 389.0
PYH1_k127_8338594_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000002636 170.0
PYH1_k127_8342374_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.776e-210 669.0
PYH1_k127_8342374_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.517e-194 616.0
PYH1_k127_8342374_2 flavin adenine dinucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001231 286.0
PYH1_k127_84454_0 - - - - 0.000000000008144 71.0
PYH1_k127_85742_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 383.0
PYH1_k127_85742_1 - - - - 0.0001514 48.0
PYH1_k127_867865_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 331.0
PYH1_k127_867865_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000001312 129.0
PYH1_k127_926846_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 466.0
PYH1_k127_926846_1 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000006639 123.0
PYH1_k127_93097_0 cellulose binding - - - 0.000000000000000000000000000007098 129.0
PYH1_k127_950085_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 325.0
PYH1_k127_963809_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 1.432e-194 619.0
PYH1_k127_963809_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 523.0
PYH1_k127_963809_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000226 290.0
PYH1_k127_963809_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000007354 147.0
PYH1_k127_963809_4 Divergent PAP2 family K09775 - - 0.00000000000000000000000000000002846 130.0
PYH1_k127_966667_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 6.575e-290 915.0
PYH1_k127_966667_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007625 242.0
PYH1_k127_970370_0 R3H domain - - - 3.557e-202 641.0
PYH1_k127_970370_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 467.0
PYH1_k127_970370_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000001238 222.0
PYH1_k127_973826_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003729 286.0
PYH1_k127_973826_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
PYH1_k127_990701_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 472.0
PYH1_k127_990701_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
PYH1_k127_990701_2 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000004607 192.0
PYH1_k127_990701_3 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000001472 187.0
PYH1_k127_990701_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000001399 152.0
PYH1_k127_990701_5 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000148 123.0
PYH1_k127_990701_6 sulfur carrier activity - - - 0.00000000000000000000001842 101.0
PYH1_k127_990701_7 - - - - 0.000000001022 61.0
PYH1_k127_990701_8 electron transfer activity K05337 - - 0.00000001502 58.0
PYH1_k127_992426_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.316e-221 701.0
PYH1_k127_992426_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000008089 215.0
PYH1_k127_992426_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000006395 183.0
PYH1_k127_992426_3 mttA/Hcf106 family K03116 - - 0.00000002003 61.0
PYH1_k127_992426_4 protein secretion K03116 - - 0.0000000846 56.0
PYH1_k127_994494_0 - - - - 0.00000000000000000000000000000000000000000000000002007 202.0
PYH1_k127_994494_1 Methyltransferase domain - - - 0.0000005094 59.0