Overview

ID MAG03171
Name PYH1_bin.8
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Syntrophobacteria
Order BM002
Family BM002
Genus JAGFXI01
Species
Assembly information
Completeness (%) 71.85
Contamination (%) 2.69
GC content (%) 61.0
N50 (bp) 5,572
Genome size (bp) 2,174,723

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2040

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1062300_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 1.959e-258 808.0
PYH1_k127_1062300_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 292.0
PYH1_k127_1062300_2 zinc-finger binding domain of transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000002043 196.0
PYH1_k127_106551_0 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 436.0
PYH1_k127_106551_1 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002102 252.0
PYH1_k127_106551_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000005028 198.0
PYH1_k127_106551_3 PFAM GAF domain protein - - - 0.0000000000000000000000000000000000001085 148.0
PYH1_k127_106551_4 - - - - 0.000000000000000002264 91.0
PYH1_k127_106551_5 - - - - 0.00002767 51.0
PYH1_k127_1068725_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 531.0
PYH1_k127_1068725_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 288.0
PYH1_k127_1068725_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001801 287.0
PYH1_k127_1068725_3 protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
PYH1_k127_1127387_0 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000001363 130.0
PYH1_k127_1127387_1 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000000000004491 91.0
PYH1_k127_1127387_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000003194 55.0
PYH1_k127_1127387_3 phosphate-selective porin O and P - - - 0.0005501 52.0
PYH1_k127_1152700_0 catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 300.0
PYH1_k127_1152700_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 293.0
PYH1_k127_1152700_2 transcriptional K03892 - - 0.00000000000000000000000002188 113.0
PYH1_k127_1152700_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000002039 64.0
PYH1_k127_1152700_4 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000168 59.0
PYH1_k127_1152700_5 - - - - 0.000000004147 63.0
PYH1_k127_1154540_0 Signal transduction response regulator, receiver domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 356.0
PYH1_k127_1154540_1 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000277 224.0
PYH1_k127_1154540_2 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000007823 60.0
PYH1_k127_1179280_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.158e-212 664.0
PYH1_k127_1179280_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 399.0
PYH1_k127_1179280_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001572 132.0
PYH1_k127_1179280_11 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000009087 129.0
PYH1_k127_1179280_12 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000001325 112.0
PYH1_k127_1179280_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000005131 94.0
PYH1_k127_1179280_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000001089 81.0
PYH1_k127_1179280_15 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001283 66.0
PYH1_k127_1179280_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 287.0
PYH1_k127_1179280_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
PYH1_k127_1179280_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
PYH1_k127_1179280_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004299 207.0
PYH1_k127_1179280_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000005351 199.0
PYH1_k127_1179280_7 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
PYH1_k127_1179280_8 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001285 177.0
PYH1_k127_1179280_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000004266 150.0
PYH1_k127_1249650_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 354.0
PYH1_k127_1249650_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000048 268.0
PYH1_k127_1249650_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000002816 205.0
PYH1_k127_1249650_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000002847 145.0
PYH1_k127_1290261_0 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000591 249.0
PYH1_k127_1290261_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000736 192.0
PYH1_k127_1290261_2 Glycosyl transferase family 41 K09667 - 2.4.1.255 0.000000000000000000000001401 120.0
PYH1_k127_1295171_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 575.0
PYH1_k127_1295171_1 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 451.0
PYH1_k127_1295171_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
PYH1_k127_1295171_3 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 314.0
PYH1_k127_1295171_4 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
PYH1_k127_1295171_5 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000006009 224.0
PYH1_k127_1295171_6 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000001242 199.0
PYH1_k127_1295171_7 PFAM AsmA family protein K07290 - - 0.0000000000000000000000000000000000002967 163.0
PYH1_k127_1295171_8 AsmA family K07289,K07290 - - 0.0000000000000000000000000000001336 145.0
PYH1_k127_1311986_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 408.0
PYH1_k127_1311986_1 Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000002076 193.0
PYH1_k127_1311986_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000002275 199.0
PYH1_k127_1311986_3 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000003783 192.0
PYH1_k127_1311986_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000008725 174.0
PYH1_k127_1311986_5 protein kinase activity - - - 0.0000000000000000000000000000001607 129.0
PYH1_k127_131788_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 4.344e-232 726.0
PYH1_k127_131788_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 531.0
PYH1_k127_131788_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 515.0
PYH1_k127_131788_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 454.0
PYH1_k127_131788_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 325.0
PYH1_k127_131788_5 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000004404 198.0
PYH1_k127_1322575_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 527.0
PYH1_k127_1322575_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 411.0
PYH1_k127_1322575_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000361 149.0
PYH1_k127_1322575_3 - - - - 0.00000000000000000000001784 109.0
PYH1_k127_1322575_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000007656 95.0
PYH1_k127_1346883_0 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000003912 156.0
PYH1_k127_1346883_1 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000005545 130.0
PYH1_k127_1346883_2 - - - - 0.000000000000000000000000000001505 123.0
PYH1_k127_1346883_3 Bacterial dnaA protein - - - 0.0000000000000001117 88.0
PYH1_k127_1346883_4 PFAM IstB-like ATP binding protein - - - 0.00000000000007417 74.0
PYH1_k127_1346883_5 COG1484 DNA replication protein - - - 0.000000001261 58.0
PYH1_k127_1346883_7 IstB-like ATP binding protein - - - 0.000215 44.0
PYH1_k127_1356617_0 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 4.561e-225 706.0
PYH1_k127_1356617_1 pfam abc K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 408.0
PYH1_k127_1356617_2 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 316.0
PYH1_k127_1356617_3 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 292.0
PYH1_k127_1361004_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 462.0
PYH1_k127_1361004_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001287 275.0
PYH1_k127_1361004_2 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000005196 172.0
PYH1_k127_1361004_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000007622 71.0
PYH1_k127_1361004_4 PilZ domain - - - 0.0008496 48.0
PYH1_k127_136528_0 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000003827 179.0
PYH1_k127_136528_1 Transcription termination factor nusG - - - 0.0000000000000000001208 96.0
PYH1_k127_136528_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000602 90.0
PYH1_k127_138244_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.457e-321 1002.0
PYH1_k127_138244_1 Threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000001284 174.0
PYH1_k127_138244_2 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000007063 115.0
PYH1_k127_138244_3 Heavy-metal-associated domain - - - 0.000000000000000000000002427 103.0
PYH1_k127_139122_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.301e-247 772.0
PYH1_k127_1405741_0 DNA photolyase K01669 - 4.1.99.3 1.173e-200 635.0
PYH1_k127_1405741_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.958e-195 623.0
PYH1_k127_1405741_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 555.0
PYH1_k127_1405741_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 427.0
PYH1_k127_1405741_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000002843 156.0
PYH1_k127_145714_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001766 169.0
PYH1_k127_145714_1 - - - - 0.000000000000000000000000000000000000008534 150.0
PYH1_k127_145714_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000003024 143.0
PYH1_k127_145714_3 Cupin 2, conserved barrel domain protein - - - 0.00000000006279 69.0
PYH1_k127_1460366_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 604.0
PYH1_k127_1460366_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000114 141.0
PYH1_k127_1460366_2 Universal stress protein K06149 - - 0.00000000000000000000000001731 111.0
PYH1_k127_1460366_3 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.0000000000000000000001316 104.0
PYH1_k127_1460366_4 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000007049 49.0
PYH1_k127_1460569_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 526.0
PYH1_k127_1460569_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 296.0
PYH1_k127_1460569_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000001516 215.0
PYH1_k127_1460569_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000002893 129.0
PYH1_k127_1460569_4 synthase K01858 - 5.5.1.4 0.000000000000000000000000000001736 120.0
PYH1_k127_1460569_5 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000001576 66.0
PYH1_k127_1514695_0 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000000000000000000000000000002905 181.0
PYH1_k127_1514695_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000004832 119.0
PYH1_k127_1555838_0 ThiF family - - - 0.00000000000000000000000000000000000223 156.0
PYH1_k127_1615003_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 445.0
PYH1_k127_1615003_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 326.0
PYH1_k127_1615003_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 307.0
PYH1_k127_1615003_3 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
PYH1_k127_1615003_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000007545 237.0
PYH1_k127_1615003_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000002501 134.0
PYH1_k127_1625471_0 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 554.0
PYH1_k127_1625471_1 DSHCT - - - 0.000000000000000000000000000000000000000000000000000000000000000000008936 246.0
PYH1_k127_165201_0 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 527.0
PYH1_k127_165201_1 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.00000000000000000000000000000000000000000000000001342 191.0
PYH1_k127_165201_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000001028 170.0
PYH1_k127_170407_0 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 425.0
PYH1_k127_170407_1 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 319.0
PYH1_k127_170407_2 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000382 241.0
PYH1_k127_170407_3 Transposase - - - 0.000000000000000000000001833 111.0
PYH1_k127_170407_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000006823 71.0
PYH1_k127_1711136_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 361.0
PYH1_k127_1711136_1 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000265 148.0
PYH1_k127_1715004_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 313.0
PYH1_k127_1715004_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
PYH1_k127_1715004_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000006456 102.0
PYH1_k127_1715004_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000419 104.0
PYH1_k127_1715004_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000008907 80.0
PYH1_k127_1715004_5 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001689 74.0
PYH1_k127_1716453_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 402.0
PYH1_k127_1716453_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000002891 213.0
PYH1_k127_1724889_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 533.0
PYH1_k127_1724889_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 367.0
PYH1_k127_1724889_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
PYH1_k127_1724889_4 DNA-templated transcription, initiation K03088 - - 0.000000000003539 71.0
PYH1_k127_1745456_0 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 461.0
PYH1_k127_1745456_1 - - - - 0.00000000000000000000000000000000003476 140.0
PYH1_k127_1745456_2 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000003235 68.0
PYH1_k127_1745456_3 - - - - 0.00002242 48.0
PYH1_k127_175262_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 352.0
PYH1_k127_175262_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007719 251.0
PYH1_k127_175262_2 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000001345 195.0
PYH1_k127_1753890_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000008982 213.0
PYH1_k127_1753890_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000002813 213.0
PYH1_k127_1753890_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000004065 213.0
PYH1_k127_1753890_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000345 175.0
PYH1_k127_1753890_4 PFAM cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000001744 118.0
PYH1_k127_180731_0 Type III restriction enzyme, res subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 413.0
PYH1_k127_180731_1 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000575 225.0
PYH1_k127_180731_2 Thioesterase superfamily - - - 0.00000000000002922 79.0
PYH1_k127_1807840_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 408.0
PYH1_k127_1807840_1 transport system involved in gliding motility auxiliary component-like K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 410.0
PYH1_k127_1807840_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 379.0
PYH1_k127_1807840_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 288.0
PYH1_k127_1807840_4 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000004241 222.0
PYH1_k127_1807840_6 - - - - 0.000000000000000007943 86.0
PYH1_k127_1807840_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000009939 84.0
PYH1_k127_1807840_8 Domain of unknown function (DUF4340) - - - 0.00000000000002704 86.0
PYH1_k127_1807840_9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000005285 63.0
PYH1_k127_180942_0 Insulinase (Peptidase family M16) K07263 - - 1.394e-199 647.0
PYH1_k127_180942_1 Fis Family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 296.0
PYH1_k127_180942_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000005994 178.0
PYH1_k127_180942_3 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000000000000000000000005953 161.0
PYH1_k127_180942_4 Initiation factor 2 subunit family K03680 - - 0.000000000000000000000000000001897 134.0
PYH1_k127_180942_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000002036 113.0
PYH1_k127_1820678_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 497.0
PYH1_k127_1820678_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 466.0
PYH1_k127_1820678_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 331.0
PYH1_k127_1820678_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000001029 229.0
PYH1_k127_1820678_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000001881 132.0
PYH1_k127_1820678_5 response to heat - - - 0.000000000000003805 79.0
PYH1_k127_1822217_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 430.0
PYH1_k127_1822217_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000152 183.0
PYH1_k127_1822217_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000001812 166.0
PYH1_k127_1822217_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000004544 55.0
PYH1_k127_1838651_0 PFAM Pyruvate carboxyltransferase - - - 2.061e-308 953.0
PYH1_k127_1838651_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.039e-257 805.0
PYH1_k127_1838651_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 498.0
PYH1_k127_1838651_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 329.0
PYH1_k127_1838651_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000005589 235.0
PYH1_k127_1838921_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.095e-198 636.0
PYH1_k127_1838921_1 Belongs to the 'phage' integrase family - - - 0.000000002561 58.0
PYH1_k127_1838921_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000001336 57.0
PYH1_k127_1838921_3 - - - - 0.0004207 45.0
PYH1_k127_1853023_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 499.0
PYH1_k127_1853023_1 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 314.0
PYH1_k127_1878321_0 Domain of Unknown Function (DUF748) - - - 2.118e-264 857.0
PYH1_k127_1878321_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000001531 184.0
PYH1_k127_1878321_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000001395 85.0
PYH1_k127_1878321_4 PFAM Tetratricopeptide - - - 0.0000361 56.0
PYH1_k127_188383_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 334.0
PYH1_k127_188383_1 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000004547 226.0
PYH1_k127_188383_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000004378 56.0
PYH1_k127_1892673_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 443.0
PYH1_k127_1892673_1 pilus assembly protein PilW - - - 0.0000000000001586 79.0
PYH1_k127_1892673_2 Prokaryotic N-terminal methylation motif K02458,K02671 - - 0.0000006633 59.0
PYH1_k127_1892673_3 Type II transport protein GspH - - - 0.000002769 57.0
PYH1_k127_1892673_4 PilX N-terminal - - - 0.000005265 57.0
PYH1_k127_1896867_0 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 6.81e-198 626.0
PYH1_k127_1896867_1 Pterin binding enzyme K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 392.0
PYH1_k127_1896867_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
PYH1_k127_1908694_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 479.0
PYH1_k127_1908694_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 432.0
PYH1_k127_1908694_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 388.0
PYH1_k127_1908694_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 314.0
PYH1_k127_1908694_4 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 288.0
PYH1_k127_1908694_5 Receptor family ligand binding region K01999 - - 0.0000000008822 64.0
PYH1_k127_1960242_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 299.0
PYH1_k127_1960242_1 General secretion pathway protein C K02452 - - 0.00000000000000000000000000000000004533 145.0
PYH1_k127_1960242_2 - - - - 0.0004737 49.0
PYH1_k127_1963596_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.698e-225 725.0
PYH1_k127_1963596_1 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 489.0
PYH1_k127_1963596_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000008779 108.0
PYH1_k127_1963596_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000005028 90.0
PYH1_k127_1986003_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 340.0
PYH1_k127_1986003_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004236 282.0
PYH1_k127_1986003_2 EamA-like transporter family - - - 0.00000000002002 70.0
PYH1_k127_1986003_3 Belongs to the HesB IscA family - - - 0.00000000007634 64.0
PYH1_k127_2000408_0 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 358.0
PYH1_k127_2000408_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005026 271.0
PYH1_k127_2000408_2 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
PYH1_k127_2033455_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
PYH1_k127_2033455_1 PFAM Protein kinase domain K05385,K12132,K13590 - 2.7.11.1,2.7.7.65 0.0000000000000000000000000000000000000000000000000304 194.0
PYH1_k127_2033455_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000004225 72.0
PYH1_k127_2047524_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 507.0
PYH1_k127_2047524_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270,K21749 - 2.7.7.43,2.7.7.92,3.1.3.45 0.0000000000000000000000000000000000000004848 157.0
PYH1_k127_20699_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 602.0
PYH1_k127_20699_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 315.0
PYH1_k127_20699_2 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000004029 141.0
PYH1_k127_20699_3 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000002353 109.0
PYH1_k127_20699_4 - K08086 - - 0.0005123 51.0
PYH1_k127_2078619_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 539.0
PYH1_k127_2078619_1 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 351.0
PYH1_k127_2131913_0 Belongs to the thiolase family K00626 - 2.3.1.9 5.627e-201 631.0
PYH1_k127_2131913_1 PFAM UspA domain protein - - - 0.000000000000000000000000000000000000000000000000000006985 202.0
PYH1_k127_2131913_2 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.000000000000000000000000000000000001186 145.0
PYH1_k127_2131913_3 Belongs to the AAA ATPase family - - - 0.00000000000000874 79.0
PYH1_k127_2131913_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ - - - 0.0001126 54.0
PYH1_k127_2131913_5 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000885 46.0
PYH1_k127_213361_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 489.0
PYH1_k127_213361_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002269 235.0
PYH1_k127_2152570_0 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 503.0
PYH1_k127_2152570_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000002238 51.0
PYH1_k127_2215989_0 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 329.0
PYH1_k127_2215989_1 - - - - 0.00000000000000000001757 97.0
PYH1_k127_2215989_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000004255 55.0
PYH1_k127_2230179_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.722e-281 870.0
PYH1_k127_2230179_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000006997 259.0
PYH1_k127_2277952_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001012 244.0
PYH1_k127_2277952_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0001907 45.0
PYH1_k127_2285715_0 4Fe-4S binding domain - - - 4.819e-266 833.0
PYH1_k127_2285715_1 PFAM major facilitator superfamily MFS_1 K03446 - - 8.046e-231 725.0
PYH1_k127_2285715_10 - - - - 0.00000000001104 68.0
PYH1_k127_2285715_11 Cupin domain K11312 - - 0.0002345 49.0
PYH1_k127_2285715_2 Aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 4.641e-215 679.0
PYH1_k127_2285715_3 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 551.0
PYH1_k127_2285715_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
PYH1_k127_2285715_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 330.0
PYH1_k127_2285715_6 Enoyl-(Acyl carrier protein) reductase K15734 - 1.1.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 294.0
PYH1_k127_2285715_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001557 280.0
PYH1_k127_2285715_8 PFAM secretion protein HlyD K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008599 275.0
PYH1_k127_2285715_9 Cupin domain K11312 - - 0.000000000000000000000001798 103.0
PYH1_k127_2309975_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.687e-221 698.0
PYH1_k127_2309975_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 434.0
PYH1_k127_2309975_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 402.0
PYH1_k127_2309975_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 304.0
PYH1_k127_2309975_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000004588 55.0
PYH1_k127_2366421_0 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 3.402e-260 813.0
PYH1_k127_2370981_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 488.0
PYH1_k127_2370981_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 354.0
PYH1_k127_2370981_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 345.0
PYH1_k127_2370981_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000002258 120.0
PYH1_k127_2370981_4 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000005412 108.0
PYH1_k127_2370981_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000002592 76.0
PYH1_k127_2374469_0 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001209 276.0
PYH1_k127_2374469_1 acetyl-CoA catabolic process K00197,K03616 - 2.1.1.245 0.00000000000000000000001508 109.0
PYH1_k127_2374469_2 Thioredoxin-like - - - 0.000000000000000009458 93.0
PYH1_k127_2374469_3 Putative regulatory protein - - - 0.000000001481 60.0
PYH1_k127_2374469_4 Putative transmembrane protein (PGPGW) - - - 0.00000008695 57.0
PYH1_k127_2375387_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.966e-320 992.0
PYH1_k127_2375387_1 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 424.0
PYH1_k127_2375387_2 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002392 293.0
PYH1_k127_2375387_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000000000002431 129.0
PYH1_k127_2375387_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000689 107.0
PYH1_k127_2375740_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000002118 85.0
PYH1_k127_2375740_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0009476 50.0
PYH1_k127_2383609_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 381.0
PYH1_k127_2383609_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000719 247.0
PYH1_k127_2383609_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000001713 246.0
PYH1_k127_2389316_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.005e-232 728.0
PYH1_k127_2389316_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 600.0
PYH1_k127_2389316_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009213 268.0
PYH1_k127_2408481_0 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 433.0
PYH1_k127_2408481_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 376.0
PYH1_k127_2408481_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001507 266.0
PYH1_k127_2408481_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008936 258.0
PYH1_k127_2408481_4 response regulator - - - 0.0000000000000001225 85.0
PYH1_k127_243372_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 443.0
PYH1_k127_243372_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 371.0
PYH1_k127_243372_2 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 305.0
PYH1_k127_243372_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006986 291.0
PYH1_k127_2442304_0 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 433.0
PYH1_k127_2442304_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005559 236.0
PYH1_k127_2442304_2 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000001023 204.0
PYH1_k127_2442304_3 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000005611 158.0
PYH1_k127_2442304_4 HNH nucleases - - - 0.0000000000000000000000000002777 115.0
PYH1_k127_2456433_0 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 436.0
PYH1_k127_2456433_1 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000000003279 168.0
PYH1_k127_2456433_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000003549 122.0
PYH1_k127_2460336_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1097.0
PYH1_k127_2460336_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 304.0
PYH1_k127_2500332_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1036.0
PYH1_k127_2500332_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 398.0
PYH1_k127_2500332_2 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000005784 234.0
PYH1_k127_2500332_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000006366 193.0
PYH1_k127_2500332_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000421 118.0
PYH1_k127_2500332_5 PFAM sigma-54 factor interaction domain-containing protein K02584,K12266 - - 0.000000784 53.0
PYH1_k127_2512762_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 458.0
PYH1_k127_2512762_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 424.0
PYH1_k127_2512762_2 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001304 293.0
PYH1_k127_2512762_3 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002427 275.0
PYH1_k127_2512762_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000008033 228.0
PYH1_k127_2524182_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 548.0
PYH1_k127_2524182_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 441.0
PYH1_k127_2524182_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000002767 268.0
PYH1_k127_2524182_3 Putative exonuclease, RdgC - - - 0.00000000000000000000000000000000000000000000000000000000002032 212.0
PYH1_k127_2524182_4 May be involved in recombination - - - 0.000000000000000000000000000000000000000000000000000776 188.0
PYH1_k127_2546601_0 Silent information regulator protein Sir2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 387.0
PYH1_k127_2546601_1 PFAM Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000002328 182.0
PYH1_k127_2546601_2 hydrolase - - - 0.00000000000000000000000000000000000000000000008811 174.0
PYH1_k127_2546601_3 - - - - 0.00000000000000000000000000000004491 134.0
PYH1_k127_2549606_0 PFAM aminotransferase, class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 369.0
PYH1_k127_2549606_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 357.0
PYH1_k127_2549606_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 352.0
PYH1_k127_2549606_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
PYH1_k127_2549606_4 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005261 281.0
PYH1_k127_2549606_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000005222 211.0
PYH1_k127_2549606_6 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000004395 148.0
PYH1_k127_2549606_7 Putative regulatory protein - - - 0.00000000000000000000000001383 110.0
PYH1_k127_2549606_8 Uroporphyrinogen-III synthase HemD K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000002157 64.0
PYH1_k127_2566580_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 572.0
PYH1_k127_2566580_1 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 268.0
PYH1_k127_2566580_2 General secretory system II protein E domain protein - - - 0.0000000000000000000005678 98.0
PYH1_k127_2566580_3 - - - - 0.0000000000000000001157 89.0
PYH1_k127_2566580_4 - - - - 0.000000000000000001822 85.0
PYH1_k127_2566580_5 ArsR family transcriptional regulator K07658 - - 0.00000001451 57.0
PYH1_k127_2566580_6 Response regulator receiver domain protein - - - 0.000006674 50.0
PYH1_k127_26110_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000001309 177.0
PYH1_k127_26110_1 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000004009 76.0
PYH1_k127_261275_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 542.0
PYH1_k127_261275_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002204 266.0
PYH1_k127_2671247_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 6.408e-197 617.0
PYH1_k127_2671247_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 501.0
PYH1_k127_2671247_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
PYH1_k127_2691134_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 421.0
PYH1_k127_2691134_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 303.0
PYH1_k127_2691134_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003138 284.0
PYH1_k127_2703973_0 Elongation factor Tu domain 2 K03833 - - 1.012e-231 733.0
PYH1_k127_2703973_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 435.0
PYH1_k127_2703973_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 405.0
PYH1_k127_2703973_3 Metallo-beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007864 257.0
PYH1_k127_2703973_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003043 254.0
PYH1_k127_2703973_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000002208 222.0
PYH1_k127_2703973_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000001827 121.0
PYH1_k127_2729859_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 334.0
PYH1_k127_2729859_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 304.0
PYH1_k127_2729859_2 ROS/MUCR transcriptional regulator protein - - - 0.0000000000002182 73.0
PYH1_k127_2731498_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.522e-281 881.0
PYH1_k127_2731498_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.552e-211 665.0
PYH1_k127_2731498_2 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 2.018e-202 635.0
PYH1_k127_2731498_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 488.0
PYH1_k127_2731498_4 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 355.0
PYH1_k127_2731498_5 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000006392 99.0
PYH1_k127_2755540_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 3.842e-229 717.0
PYH1_k127_2755540_1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 447.0
PYH1_k127_2755540_2 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 353.0
PYH1_k127_2755540_3 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000001326 205.0
PYH1_k127_2755540_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000001801 145.0
PYH1_k127_2780032_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000007807 192.0
PYH1_k127_2780032_1 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000638 184.0
PYH1_k127_2780032_2 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000002374 134.0
PYH1_k127_2780032_3 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000001657 79.0
PYH1_k127_2791869_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.841e-268 850.0
PYH1_k127_2791869_1 RNB K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 552.0
PYH1_k127_2791869_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 432.0
PYH1_k127_2791869_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 429.0
PYH1_k127_2791869_4 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 404.0
PYH1_k127_2791869_5 CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 311.0
PYH1_k127_2791869_6 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
PYH1_k127_2791869_7 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000445 258.0
PYH1_k127_2791869_8 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000003908 236.0
PYH1_k127_2791869_9 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.000000000000000000264 94.0
PYH1_k127_2817826_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 444.0
PYH1_k127_2817826_1 Lipopolysaccharide-assembly - - - 0.00000000000000000002737 99.0
PYH1_k127_2817826_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000881 77.0
PYH1_k127_2817826_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07775 - - 0.0000000000000313 77.0
PYH1_k127_2817826_4 PFAM HD domain K07814 - - 0.000001436 53.0
PYH1_k127_2817826_5 Thioesterase superfamily - - - 0.000191 50.0
PYH1_k127_2826185_0 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000002895 244.0
PYH1_k127_2826185_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000006376 195.0
PYH1_k127_2826185_2 peptidyl-tyrosine sulfation - - - 0.00000000000000001057 91.0
PYH1_k127_2826185_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00005738 49.0
PYH1_k127_2829566_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 4.2e-280 869.0
PYH1_k127_2829566_1 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 367.0
PYH1_k127_2829566_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 330.0
PYH1_k127_2829566_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000001718 133.0
PYH1_k127_2836983_0 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 412.0
PYH1_k127_2836983_1 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 265.0
PYH1_k127_2836983_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000002806 170.0
PYH1_k127_2836983_3 CHAT domain - - - 0.0000000000000000000000000000000002905 145.0
PYH1_k127_2842660_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.943e-311 960.0
PYH1_k127_2842660_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000006944 156.0
PYH1_k127_2842660_2 Mut7-C ubiquitin - - - 0.00000000000000000007057 93.0
PYH1_k127_2907026_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 418.0
PYH1_k127_2907026_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 291.0
PYH1_k127_2907026_2 PASTA K12132 - 2.7.11.1 0.000000000000000000000000000000000000001928 162.0
PYH1_k127_2907026_3 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000004514 99.0
PYH1_k127_2907026_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00001349 47.0
PYH1_k127_2908960_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 466.0
PYH1_k127_2908960_1 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 420.0
PYH1_k127_2908960_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 363.0
PYH1_k127_2908960_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 350.0
PYH1_k127_2908960_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 313.0
PYH1_k127_2908960_5 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 295.0
PYH1_k127_2908960_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000167 183.0
PYH1_k127_2908960_7 ACT domain - - - 0.000000000000000201 79.0
PYH1_k127_2922952_0 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 462.0
PYH1_k127_2922952_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
PYH1_k127_2922952_2 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 322.0
PYH1_k127_2922952_4 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000009035 164.0
PYH1_k127_2924_0 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 468.0
PYH1_k127_2924_1 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000001153 160.0
PYH1_k127_2965286_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 473.0
PYH1_k127_2965286_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 318.0
PYH1_k127_2965286_2 Jag_N K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
PYH1_k127_2965286_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000004988 54.0
PYH1_k127_2983827_0 PFAM type II secretion system K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 418.0
PYH1_k127_2983827_1 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000003595 210.0
PYH1_k127_2983827_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000002963 123.0
PYH1_k127_3011184_0 extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
PYH1_k127_3011184_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 305.0
PYH1_k127_3011184_2 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000001539 193.0
PYH1_k127_3011184_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.0000000000000000000000000000000000506 149.0
PYH1_k127_3062208_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 306.0
PYH1_k127_3062208_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000004043 136.0
PYH1_k127_3062208_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000001515 95.0
PYH1_k127_3062208_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000000000000006696 85.0
PYH1_k127_3071620_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 413.0
PYH1_k127_3071620_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 350.0
PYH1_k127_3071620_2 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 300.0
PYH1_k127_3104514_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 454.0
PYH1_k127_3104514_1 Amidohydrolase family K01305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 408.0
PYH1_k127_3104514_2 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000006733 230.0
PYH1_k127_3104514_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000001235 230.0
PYH1_k127_3104514_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH1_k127_3104514_5 Dodecin K09165 - - 0.00000000000000000000000001676 114.0
PYH1_k127_3106030_0 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 374.0
PYH1_k127_3106030_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 289.0
PYH1_k127_3106030_2 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000001751 248.0
PYH1_k127_3106531_0 recombinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 291.0
PYH1_k127_3106531_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000004829 254.0
PYH1_k127_3106531_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000004418 198.0
PYH1_k127_3106531_3 Recombinase - - - 0.000000000000000000000001907 104.0
PYH1_k127_3169006_0 Peptidase dimerisation domain - - - 1.795e-211 665.0
PYH1_k127_3169006_1 Major Facilitator Superfamily K08161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002939 253.0
PYH1_k127_3169006_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000199 236.0
PYH1_k127_3169006_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH1_k127_3169006_4 Sulphur transport K07112 - - 0.00005518 49.0
PYH1_k127_3188960_0 Pyridine nucleotide-disulphide oxidoreductase - - - 6.276e-293 906.0
PYH1_k127_3188960_1 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 465.0
PYH1_k127_3188960_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 366.0
PYH1_k127_3188960_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 334.0
PYH1_k127_3188960_4 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004762 271.0
PYH1_k127_3188960_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000361 246.0
PYH1_k127_3188960_6 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000004692 211.0
PYH1_k127_3188960_7 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000002144 96.0
PYH1_k127_324175_0 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 421.0
PYH1_k127_324175_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 300.0
PYH1_k127_3257760_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 516.0
PYH1_k127_3257760_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 316.0
PYH1_k127_3257760_2 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001138 261.0
PYH1_k127_3257760_3 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000000004288 198.0
PYH1_k127_3257760_4 1,4-alpha-glucan branching enzyme activity - - - 0.00000000000000000000000000000000000001182 146.0
PYH1_k127_3257760_5 response regulator, receiver - - - 0.00000000000000000009254 99.0
PYH1_k127_3276775_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 431.0
PYH1_k127_3276775_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 421.0
PYH1_k127_3276775_10 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000005589 60.0
PYH1_k127_3276775_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 406.0
PYH1_k127_3276775_3 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000703 188.0
PYH1_k127_3276775_4 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000006379 136.0
PYH1_k127_3276775_5 DsrC like protein K11179 - - 0.0000000000000000000000000000004435 125.0
PYH1_k127_3276775_6 - - - - 0.0000000000000000001912 95.0
PYH1_k127_3276775_7 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000002486 69.0
PYH1_k127_3276775_8 - - - - 0.000000000006371 69.0
PYH1_k127_3276775_9 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000003329 65.0
PYH1_k127_3277670_0 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005215 264.0
PYH1_k127_3277670_1 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000002352 254.0
PYH1_k127_3277670_2 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000001464 196.0
PYH1_k127_3277670_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000001888 172.0
PYH1_k127_3288200_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 565.0
PYH1_k127_3288200_1 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000002538 192.0
PYH1_k127_3288200_2 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000001334 156.0
PYH1_k127_3288200_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000001195 148.0
PYH1_k127_3288200_4 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000005028 126.0
PYH1_k127_3288200_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000731 51.0
PYH1_k127_3330905_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1122.0
PYH1_k127_3330905_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 592.0
PYH1_k127_3330905_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 465.0
PYH1_k127_3330905_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000004856 185.0
PYH1_k127_3330905_4 BioY family K03523 - - 0.000000000000000000000000000000000000000000012 169.0
PYH1_k127_3330905_5 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000005903 169.0
PYH1_k127_3330905_6 Helix-turn-helix domain K15539 - - 0.0000000000000000000002598 109.0
PYH1_k127_3391646_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1075.0
PYH1_k127_3391646_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 544.0
PYH1_k127_3391646_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 298.0
PYH1_k127_3391646_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000009668 214.0
PYH1_k127_3391646_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000001484 210.0
PYH1_k127_3391646_5 - - - - 0.00000000000001833 75.0
PYH1_k127_3393143_0 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 325.0
PYH1_k127_3396980_0 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 438.0
PYH1_k127_3396980_1 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 293.0
PYH1_k127_3396980_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.0000000000000000000000000000000000000000000000000000009172 198.0
PYH1_k127_3396980_3 ubiE/COQ5 methyltransferase family - - - 0.0000003315 56.0
PYH1_k127_3396980_4 Nuclease-related domain - - - 0.0000008455 51.0
PYH1_k127_3412204_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 3.76e-211 662.0
PYH1_k127_3412204_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 577.0
PYH1_k127_3412204_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 416.0
PYH1_k127_3412204_3 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000392 44.0
PYH1_k127_3435752_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 9.207e-204 643.0
PYH1_k127_3435752_1 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 614.0
PYH1_k127_3435752_10 Protein of unknown function (DUF1285) K09986 - - 0.00000000000132 76.0
PYH1_k127_3435752_11 DUF218 domain - - - 0.000005261 52.0
PYH1_k127_3435752_2 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 426.0
PYH1_k127_3435752_3 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 294.0
PYH1_k127_3435752_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000004842 271.0
PYH1_k127_3435752_5 DJ-1/PfpI family K03152,K05520,K05687,K12132 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 2.7.11.1,3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
PYH1_k127_3435752_6 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
PYH1_k127_3435752_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003414 243.0
PYH1_k127_3435752_8 - - - - 0.000000000000000000000000000000000000000000000000004759 185.0
PYH1_k127_3435752_9 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000003004 128.0
PYH1_k127_3443590_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 507.0
PYH1_k127_3443590_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000001591 220.0
PYH1_k127_3447012_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.759e-259 808.0
PYH1_k127_3447012_1 BadF BadG BcrA BcrD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 562.0
PYH1_k127_3447012_2 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000000000000000000000001075 213.0
PYH1_k127_3447012_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000001473 200.0
PYH1_k127_3469363_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 398.0
PYH1_k127_3469363_1 - - - - 0.000000000000000000003433 100.0
PYH1_k127_3469363_2 pfam abc1 K03688 - - 0.0000000001998 61.0
PYH1_k127_3487392_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 531.0
PYH1_k127_3487392_1 PFAM ATP-binding region ATPase domain protein K02482,K10819 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 439.0
PYH1_k127_3487392_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 383.0
PYH1_k127_3487392_3 cheY-homologous receiver domain K07658 - - 0.00000000000000000002022 97.0
PYH1_k127_3487392_4 response regulator K02481,K07715 - - 0.00000001136 61.0
PYH1_k127_3493273_0 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 479.0
PYH1_k127_3493273_1 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000166 122.0
PYH1_k127_3493273_2 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000007848 70.0
PYH1_k127_3493273_3 - - - - 0.0001221 50.0
PYH1_k127_3530506_0 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 419.0
PYH1_k127_3530506_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 338.0
PYH1_k127_3530506_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000001179 188.0
PYH1_k127_3530506_3 PFAM Cyclic nucleotide-binding K10914 - - 0.000000000189 70.0
PYH1_k127_3530506_4 Uncharacterised ArCR, COG2043 - - - 0.0003809 48.0
PYH1_k127_3535107_0 Permease, YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
PYH1_k127_3535107_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 317.0
PYH1_k127_3535107_2 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 303.0
PYH1_k127_3535107_3 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
PYH1_k127_3535107_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000004159 261.0
PYH1_k127_3535107_5 acetyltransferase - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000001548 220.0
PYH1_k127_3542124_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 391.0
PYH1_k127_3542124_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000002145 210.0
PYH1_k127_3542124_2 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000001279 168.0
PYH1_k127_3542124_3 EamA-like transporter family K08978 - - 0.0000000000000000000000000003215 118.0
PYH1_k127_3542124_4 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000003317 114.0
PYH1_k127_3542124_5 Hydrolase K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3 0.00004836 53.0
PYH1_k127_3542237_0 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 303.0
PYH1_k127_3542237_1 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003582 286.0
PYH1_k127_3542237_2 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004407 276.0
PYH1_k127_3542237_3 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000002039 186.0
PYH1_k127_3542237_4 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000002225 173.0
PYH1_k127_3542237_5 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000000000003086 123.0
PYH1_k127_3582759_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 392.0
PYH1_k127_3582759_1 Triosephosphate isomerase K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 308.0
PYH1_k127_3582759_2 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000113 193.0
PYH1_k127_3582759_3 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000004105 103.0
PYH1_k127_3582759_4 Belongs to the HpcH HpaI aldolase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000003958 95.0
PYH1_k127_3582759_5 Oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.00000000001335 64.0
PYH1_k127_358362_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1394.0
PYH1_k127_358362_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 574.0
PYH1_k127_358362_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 433.0
PYH1_k127_358362_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008647 271.0
PYH1_k127_358362_4 Efflux pump membrane transporter K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001596 241.0
PYH1_k127_3626820_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 350.0
PYH1_k127_3626820_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000005933 213.0
PYH1_k127_3626820_2 Cache 3/Cache 2 fusion domain K03406 - - 0.000000000001629 78.0
PYH1_k127_3626820_3 Tetratricopeptide repeat - - - 0.0000000002074 71.0
PYH1_k127_3627067_0 Conserved region in glutamate synthase - - - 8.215e-293 905.0
PYH1_k127_3627067_1 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008958 284.0
PYH1_k127_3627067_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 272.0
PYH1_k127_3627067_3 glutamate synthase alpha subunit domain protein - - - 0.000000000000000000000000000000000000000004414 156.0
PYH1_k127_3627067_4 4Fe-4S binding domain K00124 - - 0.0003847 46.0
PYH1_k127_363316_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 445.0
PYH1_k127_363316_1 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001307 229.0
PYH1_k127_363316_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000185 219.0
PYH1_k127_363316_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000001031 212.0
PYH1_k127_3635761_0 Belongs to the ClpX chaperone family - - - 8.641e-224 707.0
PYH1_k127_3635761_1 PFAM Radical SAM K22226 - - 6.262e-213 668.0
PYH1_k127_3635761_2 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 318.0
PYH1_k127_3635761_3 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 301.0
PYH1_k127_3635761_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000002129 184.0
PYH1_k127_3635761_5 transposase activity - - - 0.00000000000000000000000000000000000000001019 160.0
PYH1_k127_3635761_6 similarity to GP 17427840 - - - 0.00002868 47.0
PYH1_k127_3639942_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 319.0
PYH1_k127_3639942_1 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 295.0
PYH1_k127_3639942_2 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000112 224.0
PYH1_k127_3639942_3 NUDIX domain - - - 0.00000000000000000000000000000000000004633 151.0
PYH1_k127_3639942_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000049 110.0
PYH1_k127_3650656_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 395.0
PYH1_k127_3650656_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
PYH1_k127_3650656_2 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.00000000000000000000000000000007456 128.0
PYH1_k127_3650656_3 metal cluster binding K06940,K18475 - - 0.00000000005717 73.0
PYH1_k127_3663805_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.698e-215 679.0
PYH1_k127_3663805_1 PFAM cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002843 299.0
PYH1_k127_3663805_2 - - - - 0.0000000000000000001476 92.0
PYH1_k127_3663805_3 Histone deacetylase domain K04768 - - 0.000000000001861 72.0
PYH1_k127_3663805_4 histone deacetylase - - - 0.0000002051 57.0
PYH1_k127_3676285_0 - - - - 1.52e-211 672.0
PYH1_k127_3695600_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 298.0
PYH1_k127_3695600_1 Glycosyl transferase, family 2 - - - 0.000000000001091 79.0
PYH1_k127_3695600_2 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000004166 57.0
PYH1_k127_3725765_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 392.0
PYH1_k127_3725765_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002345 266.0
PYH1_k127_3725765_2 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000001221 204.0
PYH1_k127_3725765_3 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000000000000003277 128.0
PYH1_k127_3725765_4 PFAM YbaK prolyl-tRNA synthetases associated domain - - - 0.00000000000000000000000000001321 125.0
PYH1_k127_3725765_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000001493 108.0
PYH1_k127_3725765_6 Histone deacetylase domain K04768 - - 0.0000000000000000000003154 98.0
PYH1_k127_3730421_0 PFAM 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
PYH1_k127_3730421_1 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
PYH1_k127_3730421_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000003581 154.0
PYH1_k127_3730421_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000001234 134.0
PYH1_k127_3735758_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 432.0
PYH1_k127_3752968_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
PYH1_k127_3752968_1 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000009395 134.0
PYH1_k127_3752968_2 HNH endonuclease - - - 0.0000000000000000000000000002863 115.0
PYH1_k127_3752968_3 PFAM Peptidase family M28 - - - 0.00001644 57.0
PYH1_k127_3798029_0 Tex-like protein N-terminal domain K06959 - - 2.109e-308 959.0
PYH1_k127_3798029_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 330.0
PYH1_k127_3823657_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.073e-195 625.0
PYH1_k127_3823657_1 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 471.0
PYH1_k127_3844856_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.675e-261 822.0
PYH1_k127_3844856_1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 402.0
PYH1_k127_3844856_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000002158 158.0
PYH1_k127_3844856_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000007756 141.0
PYH1_k127_3857628_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 438.0
PYH1_k127_3857628_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 434.0
PYH1_k127_3857628_2 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 385.0
PYH1_k127_3857628_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001349 251.0
PYH1_k127_3857628_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
PYH1_k127_3857628_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
PYH1_k127_3857628_6 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000001384 208.0
PYH1_k127_3857628_7 TIGRFAM maf protein K06287 - - 0.00000000000000000000000000000000000000000000000000009996 193.0
PYH1_k127_3857628_8 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000000000000000000000007977 181.0
PYH1_k127_3857628_9 - - - - 0.00000000000000000000002661 106.0
PYH1_k127_3866641_0 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 479.0
PYH1_k127_3866641_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000002301 187.0
PYH1_k127_3866641_2 hexose biosynthetic process K01810 - 5.3.1.9 0.00000000000000000000000000000000003383 137.0
PYH1_k127_3877302_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.116e-214 680.0
PYH1_k127_3877302_1 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 443.0
PYH1_k127_3877302_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 331.0
PYH1_k127_3877302_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006935 271.0
PYH1_k127_3908589_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1334.0
PYH1_k127_3908589_1 4Fe-4S dicluster domain K00371 - 1.7.5.1 1.853e-203 643.0
PYH1_k127_3908589_2 nitrite transmembrane transporter activity K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 400.0
PYH1_k127_3908589_3 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
PYH1_k127_3908589_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000006709 125.0
PYH1_k127_3908589_5 Nitrate reductase delta subunit K00373 - - 0.00000000000000000000000000001724 124.0
PYH1_k127_3908589_6 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000001882 101.0
PYH1_k127_3924070_0 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 340.0
PYH1_k127_3924070_1 Potential Queuosine, Q, salvage protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 308.0
PYH1_k127_3924070_2 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000002097 102.0
PYH1_k127_3924070_3 Forkhead associated domain - - - 0.00000000279 61.0
PYH1_k127_3924616_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 3.863e-257 805.0
PYH1_k127_3924616_1 Nucleoside recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 587.0
PYH1_k127_3924616_2 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 294.0
PYH1_k127_3924616_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 287.0
PYH1_k127_3924616_4 peptidyl-tyrosine sulfation - - - 0.0000000000000001287 91.0
PYH1_k127_3994804_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 418.0
PYH1_k127_3994804_1 Binding-protein-dependent transport system inner membrane component K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 400.0
PYH1_k127_3994804_2 PFAM ABC transporter related K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 383.0
PYH1_k127_3994804_3 SMART regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000009626 242.0
PYH1_k127_3994804_4 NMT1-like family K02051,K15553 - - 0.00000000000000000000000000000000000000000000006489 171.0
PYH1_k127_3995076_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1201.0
PYH1_k127_3995076_1 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 589.0
PYH1_k127_3995076_2 CheY-like receiver, AAA-type ATPase, and DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 540.0
PYH1_k127_3995076_3 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 388.0
PYH1_k127_3995076_4 PFAM UspA domain protein - - - 0.0000000000000000000000000000000000000000001817 171.0
PYH1_k127_3995076_5 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000007711 79.0
PYH1_k127_3995076_6 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000007199 64.0
PYH1_k127_3995076_8 - - - - 0.00001962 50.0
PYH1_k127_4044_0 CoA binding domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 626.0
PYH1_k127_4044_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 427.0
PYH1_k127_4044_10 Prokaryotic N-terminal methylation motif - - - 0.0006963 48.0
PYH1_k127_4044_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 332.0
PYH1_k127_4044_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008968 275.0
PYH1_k127_4044_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001192 270.0
PYH1_k127_4044_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000001415 180.0
PYH1_k127_4044_7 Tetratricopeptide repeat - - - 0.0000000003602 70.0
PYH1_k127_4044_8 RDD family - - - 0.0000001229 63.0
PYH1_k127_4055285_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1489.0
PYH1_k127_4055285_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 355.0
PYH1_k127_4055285_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
PYH1_k127_4055285_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000009473 229.0
PYH1_k127_4055285_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002637 159.0
PYH1_k127_4055285_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000879 151.0
PYH1_k127_4055285_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000009058 88.0
PYH1_k127_4055285_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000005297 83.0
PYH1_k127_4055285_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000002154 70.0
PYH1_k127_4056258_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 400.0
PYH1_k127_4056258_1 radical SAM domain protein K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 393.0
PYH1_k127_4056258_2 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000000000000000000000000001262 200.0
PYH1_k127_4056258_3 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000003118 158.0
PYH1_k127_4056258_4 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000003143 152.0
PYH1_k127_4056258_5 Cold shock protein domain K03704 - - 0.000000000000000000000000002904 111.0
PYH1_k127_4056258_6 ParB domain protein nuclease K03497 - - 0.00000000000000000000000355 114.0
PYH1_k127_4056258_7 Biotin-requiring enzyme - - - 0.0000001009 53.0
PYH1_k127_4063923_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 287.0
PYH1_k127_4063923_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000005641 214.0
PYH1_k127_4063923_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001261 214.0
PYH1_k127_4063923_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000526 184.0
PYH1_k127_4063923_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001147 151.0
PYH1_k127_4063923_5 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001776 154.0
PYH1_k127_4063923_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002278 127.0
PYH1_k127_4063923_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001199 115.0
PYH1_k127_4063923_8 structural constituent of ribosome K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000002662 72.0
PYH1_k127_4106504_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.456e-229 717.0
PYH1_k127_4106504_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000004603 124.0
PYH1_k127_4106504_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000001031 118.0
PYH1_k127_4106504_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000002583 115.0
PYH1_k127_4106504_4 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000002817 79.0
PYH1_k127_4106504_5 Belongs to the ParB family K03497 - - 0.000000000003517 69.0
PYH1_k127_4106504_6 ATP synthesis coupled proton transport K02109 - - 0.0000008717 57.0
PYH1_k127_4118368_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 357.0
PYH1_k127_4118368_1 ATPase involved in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 349.0
PYH1_k127_4118368_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 300.0
PYH1_k127_4118368_3 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000001087 153.0
PYH1_k127_4118368_4 - - - - 0.000000000000000000000000003475 116.0
PYH1_k127_4118368_5 - - - - 0.00006979 53.0
PYH1_k127_4159458_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 4.668e-263 832.0
PYH1_k127_4159458_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 467.0
PYH1_k127_4159458_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 455.0
PYH1_k127_4159458_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 274.0
PYH1_k127_4159458_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000002628 117.0
PYH1_k127_4159458_5 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000009872 84.0
PYH1_k127_4177796_0 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 490.0
PYH1_k127_4177796_1 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 432.0
PYH1_k127_4177796_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 285.0
PYH1_k127_4177796_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001883 276.0
PYH1_k127_4177796_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000001113 161.0
PYH1_k127_4207681_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0 1288.0
PYH1_k127_4207681_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 550.0
PYH1_k127_4207681_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 342.0
PYH1_k127_4207681_3 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000005134 261.0
PYH1_k127_4207681_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000004166 178.0
PYH1_k127_4207681_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000001457 151.0
PYH1_k127_4207681_6 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000004502 148.0
PYH1_k127_4207681_7 Belongs to the 'phage' integrase family - - - 0.0000000000000000000007972 98.0
PYH1_k127_4207681_8 Helix-turn-helix XRE-family like proteins - - - 0.000002807 51.0
PYH1_k127_4207681_9 GAF domain - - - 0.000003198 55.0
PYH1_k127_4211535_0 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 462.0
PYH1_k127_4211535_1 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 317.0
PYH1_k127_4211535_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001915 286.0
PYH1_k127_4211535_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 259.0
PYH1_k127_4211535_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001824 252.0
PYH1_k127_4211535_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000609 95.0
PYH1_k127_4211535_6 - - - - 0.0006419 52.0
PYH1_k127_4224735_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1075.0
PYH1_k127_4224735_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 449.0
PYH1_k127_4224735_2 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 328.0
PYH1_k127_4224735_3 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000542 146.0
PYH1_k127_4237961_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.82e-231 720.0
PYH1_k127_4237961_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 548.0
PYH1_k127_4237961_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000004156 205.0
PYH1_k127_4237961_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000004622 194.0
PYH1_k127_4237961_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000005196 182.0
PYH1_k127_4253192_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.496e-203 640.0
PYH1_k127_4253192_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 422.0
PYH1_k127_4253192_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 392.0
PYH1_k127_4253192_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004201 254.0
PYH1_k127_4266396_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 413.0
PYH1_k127_4266396_1 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000000006105 145.0
PYH1_k127_4287813_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 2.182e-211 668.0
PYH1_k127_4287813_1 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 552.0
PYH1_k127_4287813_10 Rubrerythrin - - - 0.00000000000000000000000003794 116.0
PYH1_k127_4287813_11 radical SAM domain protein - - - 0.00000000001179 68.0
PYH1_k127_4287813_12 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000001261 65.0
PYH1_k127_4287813_13 deoxyhypusine monooxygenase activity - - - 0.0001046 55.0
PYH1_k127_4287813_2 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 472.0
PYH1_k127_4287813_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 460.0
PYH1_k127_4287813_4 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 350.0
PYH1_k127_4287813_5 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 335.0
PYH1_k127_4287813_6 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004364 282.0
PYH1_k127_4287813_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001861 284.0
PYH1_k127_4287813_8 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002738 267.0
PYH1_k127_4287813_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000658 216.0
PYH1_k127_4319081_0 PFAM Acyl-CoA dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 507.0
PYH1_k127_4319081_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 464.0
PYH1_k127_4319081_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 384.0
PYH1_k127_4319081_3 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000003889 210.0
PYH1_k127_4323366_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 515.0
PYH1_k127_4323366_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 339.0
PYH1_k127_4323366_2 Cold shock protein domain K03704 - - 0.0000000000000000000001615 98.0
PYH1_k127_4323366_3 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.000001061 57.0
PYH1_k127_4336117_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1033.0
PYH1_k127_4339410_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0 1037.0
PYH1_k127_4339410_1 integrase domain protein SAM domain protein K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
PYH1_k127_4339410_2 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000006149 124.0
PYH1_k127_4342734_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 432.0
PYH1_k127_4342734_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 334.0
PYH1_k127_4342734_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005658 269.0
PYH1_k127_4342734_3 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000001243 248.0
PYH1_k127_4342734_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000003115 165.0
PYH1_k127_4342734_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000131 155.0
PYH1_k127_4342734_6 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003259 140.0
PYH1_k127_4342734_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000009434 123.0
PYH1_k127_4390742_0 acetyl-CoA K18122,K18288 - - 4.513e-250 787.0
PYH1_k127_4390742_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.499e-221 695.0
PYH1_k127_4390742_10 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000001337 229.0
PYH1_k127_4390742_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000001274 209.0
PYH1_k127_4390742_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000004452 186.0
PYH1_k127_4390742_13 - - - - 0.0000000005468 67.0
PYH1_k127_4390742_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 378.0
PYH1_k127_4390742_3 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 365.0
PYH1_k127_4390742_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 332.0
PYH1_k127_4390742_5 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
PYH1_k127_4390742_6 nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
PYH1_k127_4390742_7 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH1_k127_4390742_8 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000006836 243.0
PYH1_k127_4390742_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
PYH1_k127_4417185_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 458.0
PYH1_k127_4417185_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 301.0
PYH1_k127_4417185_2 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000005839 142.0
PYH1_k127_4417185_3 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000001297 136.0
PYH1_k127_4417185_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000005898 104.0
PYH1_k127_4418024_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2232.0
PYH1_k127_4418024_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.568e-313 970.0
PYH1_k127_4418024_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001602 237.0
PYH1_k127_4418024_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000009038 231.0
PYH1_k127_4418024_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000179 76.0
PYH1_k127_4429338_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 469.0
PYH1_k127_4429338_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007654 252.0
PYH1_k127_4429338_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000061 148.0
PYH1_k127_4429338_3 Rubrerythrin - - - 0.00000000000000000000002516 100.0
PYH1_k127_4431612_0 L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000001511 157.0
PYH1_k127_4431612_1 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000001214 114.0
PYH1_k127_4431612_2 Regulatory protein, FmdB family - - - 0.00000000000000000008195 91.0
PYH1_k127_4431612_3 Uncharacterized protein family UPF0016 - - - 0.0000000000000000005572 90.0
PYH1_k127_4431612_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000001269 56.0
PYH1_k127_4431612_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000005659 60.0
PYH1_k127_4431612_6 PFAM nuclease (SNase domain protein) - - - 0.0000008834 50.0
PYH1_k127_444807_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001989 201.0
PYH1_k127_444807_1 Fimbrial assembly family protein K02461 - - 0.0000000000000000000000003001 121.0
PYH1_k127_444807_2 Pfam:N_methyl_2 K02458 - - 0.0000000001018 69.0
PYH1_k127_4464752_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 618.0
PYH1_k127_4464752_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 370.0
PYH1_k127_4464752_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000004792 198.0
PYH1_k127_4464752_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000002563 156.0
PYH1_k127_4464752_4 Belongs to the Fur family K03711 - - 0.000000000000000000000003548 104.0
PYH1_k127_4468659_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 567.0
PYH1_k127_4468659_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 573.0
PYH1_k127_4468659_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001897 249.0
PYH1_k127_4468659_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000005693 228.0
PYH1_k127_4522550_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 567.0
PYH1_k127_4522550_1 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 415.0
PYH1_k127_4522550_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004286 276.0
PYH1_k127_4522550_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000003466 142.0
PYH1_k127_4522550_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000003587 125.0
PYH1_k127_4522550_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000191 116.0
PYH1_k127_4526935_0 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 566.0
PYH1_k127_4526935_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000001609 165.0
PYH1_k127_4526935_2 diguanylate cyclase - - - 0.000000633 58.0
PYH1_k127_4547270_0 PFAM HhH-GPD superfamily base excision DNA repair protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 315.0
PYH1_k127_4547270_1 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008945 274.0
PYH1_k127_4547270_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000005124 222.0
PYH1_k127_4547270_3 PFAM natural resistance-associated macrophage protein K03322 - - 0.00000000000000000000000000000000001363 138.0
PYH1_k127_4547270_4 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000002749 127.0
PYH1_k127_4547270_5 PFAM plasmid K06218 - - 0.0000000000000000000000000818 108.0
PYH1_k127_4547270_7 ATPase (AAA superfamily K07133 - - 0.00008779 49.0
PYH1_k127_4556894_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 401.0
PYH1_k127_4556894_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000002611 164.0
PYH1_k127_4556894_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000008689 147.0
PYH1_k127_4556894_3 Prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.00000000000000000000000008521 113.0
PYH1_k127_4560067_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 9.338e-196 625.0
PYH1_k127_4560067_1 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 620.0
PYH1_k127_4560067_2 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 321.0
PYH1_k127_4560067_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000002552 199.0
PYH1_k127_4560067_4 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000007508 187.0
PYH1_k127_4567017_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.009e-216 694.0
PYH1_k127_4567017_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 2.788e-197 627.0
PYH1_k127_4567017_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 271.0
PYH1_k127_4583997_0 Major facilitator Superfamily K03292 - - 5.14e-198 627.0
PYH1_k127_4583997_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 483.0
PYH1_k127_4583997_2 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 371.0
PYH1_k127_4583997_3 Membrane - - - 0.000000000000000000000000000000000000000000000117 171.0
PYH1_k127_4583997_4 lipid a biosynthesis K02517 - 2.3.1.241 0.0001025 46.0
PYH1_k127_4584946_0 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 411.0
PYH1_k127_4584946_1 ABC transporter K02065 - - 0.000000000000000009543 84.0
PYH1_k127_4584946_2 Response regulator receiver - - - 0.0000000000000002008 85.0
PYH1_k127_4584946_3 - - - - 0.0000000000001175 82.0
PYH1_k127_4586571_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.824e-207 686.0
PYH1_k127_459715_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003447 226.0
PYH1_k127_459715_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000005154 223.0
PYH1_k127_459715_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000008793 189.0
PYH1_k127_4603550_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 386.0
PYH1_k127_4603550_1 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 359.0
PYH1_k127_4603550_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
PYH1_k127_4603550_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 265.0
PYH1_k127_4603550_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
PYH1_k127_4603550_5 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000003706 137.0
PYH1_k127_4613042_0 -binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 332.0
PYH1_k127_4613042_1 Psort location Cytoplasmic, score K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000514 258.0
PYH1_k127_4613042_2 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.00000000006293 64.0
PYH1_k127_46490_0 PFAM Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.734e-251 785.0
PYH1_k127_46490_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 425.0
PYH1_k127_46490_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.00000005116 59.0
PYH1_k127_4650890_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.749e-212 666.0
PYH1_k127_4650890_1 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 342.0
PYH1_k127_4650890_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001549 259.0
PYH1_k127_4650890_3 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
PYH1_k127_4650890_4 PFAM cytoplasmic chaperone TorD family protein - - - 0.0000000000000000000000000000000000000003912 158.0
PYH1_k127_4681066_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 369.0
PYH1_k127_4681066_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 292.0
PYH1_k127_4683952_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1057.0
PYH1_k127_4683952_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 1.238e-308 986.0
PYH1_k127_4683952_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 554.0
PYH1_k127_4692989_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
PYH1_k127_4692989_1 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000005198 100.0
PYH1_k127_4692989_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000001015 96.0
PYH1_k127_4692989_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000002651 68.0
PYH1_k127_4726249_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 350.0
PYH1_k127_4726249_1 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000002259 242.0
PYH1_k127_4726249_2 PilZ domain K07001,K07003,K10914 - - 0.00007976 50.0
PYH1_k127_4762640_0 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 601.0
PYH1_k127_4762640_1 nitrogen compound transport K02033,K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 426.0
PYH1_k127_4762640_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 419.0
PYH1_k127_4762640_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 362.0
PYH1_k127_4762640_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 354.0
PYH1_k127_4762640_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 337.0
PYH1_k127_4762640_6 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000002372 231.0
PYH1_k127_4762640_7 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000009851 196.0
PYH1_k127_4762640_8 CheB methylesterase - - - 0.00000000000000000000000000000000000000000000000003658 186.0
PYH1_k127_4764414_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 2.69e-225 722.0
PYH1_k127_4764414_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 411.0
PYH1_k127_4764414_2 endonuclease III - - - 0.0000000000000000000000000000000000000000000001914 173.0
PYH1_k127_4764414_3 - - - - 0.000000000000000000000000000000258 131.0
PYH1_k127_4774123_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1029.0
PYH1_k127_4774123_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.526e-214 672.0
PYH1_k127_4774123_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 333.0
PYH1_k127_4774123_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000001071 228.0
PYH1_k127_4856768_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 370.0
PYH1_k127_4856768_1 FAD linked K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000002417 168.0
PYH1_k127_4856768_2 - - - - 0.0006574 46.0
PYH1_k127_4868101_0 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
PYH1_k127_4868101_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 291.0
PYH1_k127_4868101_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000001148 119.0
PYH1_k127_4868101_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000003644 89.0
PYH1_k127_4868101_4 Plasmid stability protein K21495 - - 0.0000000000001029 73.0
PYH1_k127_4868101_5 Glycine-zipper domain - - - 0.0000007958 57.0
PYH1_k127_4868101_6 Protein of unknown function (DUF2845) - - - 0.0008041 47.0
PYH1_k127_4902316_0 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 580.0
PYH1_k127_4902316_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 530.0
PYH1_k127_4902316_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 365.0
PYH1_k127_4902316_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000002805 178.0
PYH1_k127_4902316_4 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.000000000000000000000000000000001425 142.0
PYH1_k127_4902316_5 Replication protein - - - 0.0000000000000000000007182 104.0
PYH1_k127_4902316_6 Smr domain - - - 0.0000000000000000002885 98.0
PYH1_k127_4927042_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 467.0
PYH1_k127_4927042_1 smart pdz dhr glgf K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 353.0
PYH1_k127_4927042_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 339.0
PYH1_k127_4932347_0 FAD linked oxidases, C-terminal domain - - - 0.0 1144.0
PYH1_k127_4932347_1 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
PYH1_k127_4932347_2 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000004928 157.0
PYH1_k127_4932347_3 ligase activity, forming nitrogen-metal bonds K02230,K03403 - 6.6.1.1,6.6.1.2 0.0000002207 53.0
PYH1_k127_4932347_4 DinB superfamily - - - 0.000000727 57.0
PYH1_k127_4938251_0 CoA binding domain K01905,K22224 - 6.2.1.13 7.631e-260 816.0
PYH1_k127_4938251_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 299.0
PYH1_k127_4938251_10 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000005682 48.0
PYH1_k127_4938251_11 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0004391 44.0
PYH1_k127_4938251_2 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 298.0
PYH1_k127_4938251_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 287.0
PYH1_k127_4938251_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 240.0
PYH1_k127_4938251_5 Thioesterase - - - 0.000000000000000000000000000000002147 131.0
PYH1_k127_4938251_6 PFAM plasmid K06218 - - 0.000000000000000000000000000003193 121.0
PYH1_k127_4938251_7 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000000002013 107.0
PYH1_k127_4938251_8 - - - - 0.0000000000000000000005387 97.0
PYH1_k127_5022369_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 503.0
PYH1_k127_5022369_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 338.0
PYH1_k127_5022369_2 Sulfotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 324.0
PYH1_k127_5022369_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000997 224.0
PYH1_k127_5084168_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 472.0
PYH1_k127_5084168_1 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 445.0
PYH1_k127_5084168_10 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000000000000000002872 146.0
PYH1_k127_5084168_11 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000547 138.0
PYH1_k127_5084168_12 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000001854 144.0
PYH1_k127_5084168_13 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000002377 127.0
PYH1_k127_5084168_14 Gaf domain K13590,K21084 - 2.7.7.65 0.0000000000000000000000002243 121.0
PYH1_k127_5084168_15 Belongs to the UPF0235 family K09131 - - 0.000000000000000000003129 97.0
PYH1_k127_5084168_16 - - - - 0.00000000000001334 76.0
PYH1_k127_5084168_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 446.0
PYH1_k127_5084168_3 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 444.0
PYH1_k127_5084168_4 ABC transporter K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 384.0
PYH1_k127_5084168_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 305.0
PYH1_k127_5084168_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 306.0
PYH1_k127_5084168_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 300.0
PYH1_k127_5084168_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
PYH1_k127_5084168_9 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002728 257.0
PYH1_k127_50862_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 572.0
PYH1_k127_50862_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000001485 188.0
PYH1_k127_50862_2 nucleotide metabolic process - - - 0.000000005492 60.0
PYH1_k127_5094140_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 404.0
PYH1_k127_5094140_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000001526 181.0
PYH1_k127_5094140_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000004268 167.0
PYH1_k127_5094140_3 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000002271 111.0
PYH1_k127_5094140_4 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000008668 81.0
PYH1_k127_5094140_5 Putative zinc- or iron-chelating domain - - - 0.00000000000943 75.0
PYH1_k127_5107042_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 305.0
PYH1_k127_5107042_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000005414 148.0
PYH1_k127_5107042_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002546 138.0
PYH1_k127_5107042_3 KH domain K06960 - - 0.00000000000000000000000000000004427 130.0
PYH1_k127_5107042_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000009113 122.0
PYH1_k127_5107042_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000006982 112.0
PYH1_k127_5119779_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 7.718e-311 995.0
PYH1_k127_5119779_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 291.0
PYH1_k127_5119779_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000007092 253.0
PYH1_k127_5119779_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000194 212.0
PYH1_k127_5135416_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.078e-220 690.0
PYH1_k127_5135416_1 PFAM Radical SAM domain protein K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 370.0
PYH1_k127_5135416_2 Transposase DDE domain K07492 - - 0.00000000001198 65.0
PYH1_k127_5152349_0 in Escherichia coli this protein forms a dimer and binds manganese K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000001011 68.0
PYH1_k127_5152349_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500,K11392,K21970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 0.00002315 47.0
PYH1_k127_5154248_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 6.033e-313 985.0
PYH1_k127_5154248_1 phosphate transport system permease protein K02038 - - 2.194e-242 774.0
PYH1_k127_5154248_10 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000008631 93.0
PYH1_k127_5154248_11 Prolipoprotein diacylglyceryl transferase - - - 0.0000000255 57.0
PYH1_k127_5154248_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 487.0
PYH1_k127_5154248_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 419.0
PYH1_k127_5154248_4 cobalamin-transporting ATPase activity K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 325.0
PYH1_k127_5154248_5 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 302.0
PYH1_k127_5154248_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 298.0
PYH1_k127_5154248_7 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000009013 243.0
PYH1_k127_5154248_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000222 217.0
PYH1_k127_5154248_9 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000002066 131.0
PYH1_k127_5212254_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.609e-226 717.0
PYH1_k127_5212254_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000003916 158.0
PYH1_k127_5212254_2 Enoyl-(Acyl carrier protein) reductase - GO:0003674,GO:0003824,GO:0004090,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.0000000000000000000000000000000000000002763 158.0
PYH1_k127_5212254_3 Domain of unknown function (DUF4258) - - - 0.000000000000000000000000000000000006109 137.0
PYH1_k127_5212254_4 EamA-like transporter family - - - 0.00000000000000000000000000000000001305 148.0
PYH1_k127_5212254_5 - - - - 0.000000000000000000009978 93.0
PYH1_k127_5212254_6 nuclease activity K06218 - - 0.000000000000006196 76.0
PYH1_k127_5212254_7 - - - - 0.00000000000001568 75.0
PYH1_k127_5212254_8 Domain of unknown function (DUF4258) - - - 0.0008175 45.0
PYH1_k127_5214934_0 aminotransferase, class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 352.0
PYH1_k127_5214934_1 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 317.0
PYH1_k127_5214934_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001554 245.0
PYH1_k127_5214934_3 DNA photolyase activity K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000001007 207.0
PYH1_k127_5214934_4 Thiamine-binding protein - - - 0.00000000000000000000000000000000001966 138.0
PYH1_k127_5214934_5 SMART Water Stress and Hypersensitive response - - - 0.000000000000000000000000597 110.0
PYH1_k127_5214934_6 FAD dependent oxidoreductase - - - 0.0000000000000000000001447 99.0
PYH1_k127_5214934_9 Protein of unknown function (DUF3365) - - - 0.0005507 48.0
PYH1_k127_5246642_0 FAD binding domain K07137 - - 8.756e-201 635.0
PYH1_k127_5246642_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 336.0
PYH1_k127_5246642_2 PFAM metal-dependent phosphohydrolase, HD sub domain K07023 - - 0.0000000000000000000000000000007313 123.0
PYH1_k127_5254079_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 407.0
PYH1_k127_5254079_1 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 289.0
PYH1_k127_5254079_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000006435 184.0
PYH1_k127_5254079_3 phosphatase activity K07025 - - 0.00000000000000000001013 100.0
PYH1_k127_5278274_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1024.0
PYH1_k127_5278274_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.916e-208 654.0
PYH1_k127_5278274_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 458.0
PYH1_k127_5278274_3 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00003648 51.0
PYH1_k127_528081_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 377.0
PYH1_k127_528081_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002032 258.0
PYH1_k127_528081_11 energy transducer activity K03646,K03832 - - 0.0000000005762 70.0
PYH1_k127_528081_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000002206 243.0
PYH1_k127_528081_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000003799 220.0
PYH1_k127_528081_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000005524 149.0
PYH1_k127_528081_5 UTP biosynthetic process - - - 0.000000000000000000000000000008019 132.0
PYH1_k127_528081_6 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000424 112.0
PYH1_k127_528081_7 Ogr/Delta-like zinc finger - - - 0.00000000000000000000004719 101.0
PYH1_k127_528081_9 Pfam SEC-C motif - - - 0.0000000000000004993 85.0
PYH1_k127_5327175_0 Cytochrome c554 and c-prime - - - 5.134e-272 851.0
PYH1_k127_5342928_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 478.0
PYH1_k127_5342928_1 - - - - 0.0000000000000000000000000000000000000000000000000001342 194.0
PYH1_k127_5349307_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 327.0
PYH1_k127_5349307_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 324.0
PYH1_k127_5349307_2 glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 291.0
PYH1_k127_5349307_3 enoyl-[acyl-carrier-protein] reductase (NADH) activity - - - 0.0000000000000000000000000000000000001602 148.0
PYH1_k127_5349307_4 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000549 138.0
PYH1_k127_5349307_5 nucleotidyltransferase activity - - - 0.00000000000000000003934 94.0
PYH1_k127_5371932_0 Transcriptional regulator - - - 0.000000000000004681 82.0
PYH1_k127_5371932_1 G-rich domain on putative tyrosine kinase - - - 0.0000001845 61.0
PYH1_k127_5377541_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 520.0
PYH1_k127_5377541_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 411.0
PYH1_k127_5377541_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000158 239.0
PYH1_k127_5501090_0 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 304.0
PYH1_k127_5501090_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 292.0
PYH1_k127_5501090_2 PFAM peptidase M29, aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000004867 170.0
PYH1_k127_5501090_3 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000007527 137.0
PYH1_k127_5501090_4 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000008487 108.0
PYH1_k127_5501090_5 Glutathione peroxidase - - - 0.000004848 57.0
PYH1_k127_551006_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 487.0
PYH1_k127_551006_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 468.0
PYH1_k127_551006_2 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000000000000000000346 211.0
PYH1_k127_551006_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000004353 197.0
PYH1_k127_551006_4 SMART Rhodanese domain protein - - - 0.00000000000000000000000000001702 126.0
PYH1_k127_551006_5 B-1 B cell differentiation - - - 0.00000001466 64.0
PYH1_k127_5557162_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 596.0
PYH1_k127_5557162_1 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 343.0
PYH1_k127_5557162_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000002855 243.0
PYH1_k127_5570618_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001453 271.0
PYH1_k127_5570618_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 268.0
PYH1_k127_5570618_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000142 196.0
PYH1_k127_5606822_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 581.0
PYH1_k127_5606822_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
PYH1_k127_5606822_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000003285 147.0
PYH1_k127_5606822_3 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.000000000000000000000000000000000000004919 155.0
PYH1_k127_5606822_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000001974 115.0
PYH1_k127_5614600_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 401.0
PYH1_k127_5614600_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 369.0
PYH1_k127_5614600_2 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000007613 191.0
PYH1_k127_5614600_3 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000001165 110.0
PYH1_k127_5628028_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 372.0
PYH1_k127_5628028_1 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 321.0
PYH1_k127_5628028_2 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 294.0
PYH1_k127_5628028_3 - - - - 0.000000000000000000000000000000000000000000000000000008293 196.0
PYH1_k127_5660695_0 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 481.0
PYH1_k127_5660695_1 PFAM CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000006985 215.0
PYH1_k127_5660695_2 His Kinase A (phosphoacceptor) domain K10819 - 2.7.13.3 0.0000000000000000000000000000000000000000000001222 188.0
PYH1_k127_5660695_3 PFAM response regulator receiver - - - 0.0000000000000000243 91.0
PYH1_k127_5660695_4 PFAM UspA domain protein - - - 0.00000002866 59.0
PYH1_k127_5673844_0 PFAM Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 377.0
PYH1_k127_5673844_1 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 285.0
PYH1_k127_5673844_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009812 277.0
PYH1_k127_5673844_3 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000375 236.0
PYH1_k127_5673844_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000006127 232.0
PYH1_k127_5673844_5 PFAM Uncharacterised ACR, COG1259 K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000008547 191.0
PYH1_k127_5673844_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000005109 99.0
PYH1_k127_5675665_0 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 305.0
PYH1_k127_5675665_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
PYH1_k127_5675665_2 - - - - 0.0000000003184 71.0
PYH1_k127_567954_0 PFAM Radical SAM K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 411.0
PYH1_k127_567954_1 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 260.0
PYH1_k127_567954_2 PFAM aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008923 237.0
PYH1_k127_567954_3 S-layer homology domain - - - 0.000000000000000000000000000000000000000000002027 174.0
PYH1_k127_5721408_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 319.0
PYH1_k127_5721408_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000002027 270.0
PYH1_k127_5721408_2 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005034 251.0
PYH1_k127_5721408_3 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002687 241.0
PYH1_k127_5721408_4 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000006482 150.0
PYH1_k127_5721408_5 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000002068 68.0
PYH1_k127_5745502_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.397e-272 845.0
PYH1_k127_5745502_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000226 183.0
PYH1_k127_5745619_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1029.0
PYH1_k127_5745619_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000001278 190.0
PYH1_k127_5745619_2 Protein of unknown function (DUF1573) - - - 0.00000000000000000368 93.0
PYH1_k127_5749278_0 Peptidase M16C associated K06972 - - 2.717e-202 643.0
PYH1_k127_5749278_1 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 312.0
PYH1_k127_5749278_2 Glutaredoxin K03676 - - 0.0000000003559 61.0
PYH1_k127_5751784_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 479.0
PYH1_k127_5751784_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000009006 181.0
PYH1_k127_5751784_2 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.0000000000000000000000000000000000000000003983 168.0
PYH1_k127_5751784_3 Conserved hypothetical protein 95 - - - 0.000000000000000000003443 95.0
PYH1_k127_5770772_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.496e-282 876.0
PYH1_k127_5770772_1 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 347.0
PYH1_k127_5770772_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH1_k127_5770772_3 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 334.0
PYH1_k127_5770772_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000004622 109.0
PYH1_k127_5770772_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000001209 100.0
PYH1_k127_5770772_6 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000006968 76.0
PYH1_k127_5808301_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 619.0
PYH1_k127_5808301_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 612.0
PYH1_k127_5808301_10 - - - - 0.00000001484 57.0
PYH1_k127_5808301_11 production of miRNAs involved in gene silencing by miRNA K04459,K13108,K21278 GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006396,GO:0006397,GO:0006403,GO:0006405,GO:0006406,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015931,GO:0016070,GO:0016071,GO:0031503,GO:0032991,GO:0033036,GO:0034613,GO:0034641,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045184,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051028,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051235,GO:0051236,GO:0051237,GO:0051641,GO:0051649,GO:0065007,GO:0065008,GO:0070274,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.1.3.16,3.1.3.48 0.00000003493 64.0
PYH1_k127_5808301_12 Putative transposase of IS4/5 family (DUF4096) - - - 0.000003296 50.0
PYH1_k127_5808301_2 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 540.0
PYH1_k127_5808301_3 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 343.0
PYH1_k127_5808301_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 290.0
PYH1_k127_5808301_5 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000005564 197.0
PYH1_k127_5808301_6 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000002652 124.0
PYH1_k127_5808301_7 TIGRFAM MJ0042 family finger-like protein - - - 0.000000000000000000000000000505 123.0
PYH1_k127_5808301_8 Sporulation and spore germination - - - 0.0000000000000000000000001216 114.0
PYH1_k127_5808301_9 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000004588 66.0
PYH1_k127_5813109_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 544.0
PYH1_k127_5813109_1 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 417.0
PYH1_k127_5813109_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000005239 195.0
PYH1_k127_5842622_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 577.0
PYH1_k127_5842622_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 388.0
PYH1_k127_5842622_10 Tetratricopeptide repeat - - - 0.0004605 44.0
PYH1_k127_5842622_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000593 230.0
PYH1_k127_5842622_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000146 177.0
PYH1_k127_5842622_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000555 124.0
PYH1_k127_5842622_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000001312 121.0
PYH1_k127_5842622_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000006351 112.0
PYH1_k127_5842622_7 - - - - 0.000000005486 64.0
PYH1_k127_5856388_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001644 251.0
PYH1_k127_5856388_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000005772 154.0
PYH1_k127_5856388_2 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000005507 139.0
PYH1_k127_5871553_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.992e-227 709.0
PYH1_k127_5871553_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 334.0
PYH1_k127_5871553_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 304.0
PYH1_k127_5871553_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
PYH1_k127_5871553_4 PFAM RimK domain protein ATP-grasp K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000001379 246.0
PYH1_k127_5871553_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000006334 228.0
PYH1_k127_5896132_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000001198 190.0
PYH1_k127_5896132_1 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000001822 184.0
PYH1_k127_5896132_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000003566 102.0
PYH1_k127_5896132_3 - - - - 0.000009839 48.0
PYH1_k127_5913171_0 serine-type endopeptidase inhibitor activity K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 373.0
PYH1_k127_5913171_1 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000002716 210.0
PYH1_k127_5913171_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000002086 187.0
PYH1_k127_5913171_3 Protein of unknown function (DUF3999) - - - 0.0000000000000000001988 102.0
PYH1_k127_5921495_0 extracellular solute-binding protein, family 5 - - - 6.445e-254 789.0
PYH1_k127_5921495_1 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 501.0
PYH1_k127_5921495_2 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 459.0
PYH1_k127_5921495_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
PYH1_k127_5921495_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 441.0
PYH1_k127_5921495_5 Dihydrodipicolinate reductase, N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 419.0
PYH1_k127_5921495_6 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 415.0
PYH1_k127_5921495_7 Lysin motif - - - 0.00000000001621 74.0
PYH1_k127_5942487_0 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
PYH1_k127_5942487_1 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000001022 82.0
PYH1_k127_5973512_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 545.0
PYH1_k127_5973512_1 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 526.0
PYH1_k127_5973512_2 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 352.0
PYH1_k127_5973512_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003973 280.0
PYH1_k127_5973512_4 self proteolysis - - - 0.00000000000000000000000000000000000001421 156.0
PYH1_k127_5974206_0 ATPase associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000001653 215.0
PYH1_k127_5974206_1 - - - - 0.0000000857 53.0
PYH1_k127_5999813_0 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 435.0
PYH1_k127_5999813_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 351.0
PYH1_k127_5999813_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000002356 196.0
PYH1_k127_6002588_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1146.0
PYH1_k127_6002588_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 383.0
PYH1_k127_6005914_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 461.0
PYH1_k127_6005914_1 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 334.0
PYH1_k127_6005914_2 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000007293 205.0
PYH1_k127_6005914_3 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000025 171.0
PYH1_k127_6015243_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1105.0
PYH1_k127_6015243_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.481e-288 892.0
PYH1_k127_6015243_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 6.285e-265 844.0
PYH1_k127_6015243_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
PYH1_k127_6015243_4 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002211 260.0
PYH1_k127_6015243_5 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000253 148.0
PYH1_k127_6015243_6 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000008623 121.0
PYH1_k127_6015243_7 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000001246 101.0
PYH1_k127_6015243_8 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000007405 99.0
PYH1_k127_6016140_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000002345 213.0
PYH1_k127_6016140_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000006051 156.0
PYH1_k127_6016140_2 PFAM alpha beta hydrolase fold - - - 0.000000001313 68.0
PYH1_k127_6016140_3 Helix-turn-helix XRE-family like proteins - - - 0.0002641 50.0
PYH1_k127_6025475_0 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 587.0
PYH1_k127_6025475_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 586.0
PYH1_k127_6025475_2 PFAM HD domain - - - 0.000000000000000000000000000000000000002906 151.0
PYH1_k127_6040365_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 485.0
PYH1_k127_6040365_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 293.0
PYH1_k127_6040365_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000004761 210.0
PYH1_k127_6040365_3 - - - - 0.00000000000001563 77.0
PYH1_k127_6042783_0 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 576.0
PYH1_k127_6042783_1 FAD binding domain K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000003307 186.0
PYH1_k127_6042783_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0000000000000000001393 89.0
PYH1_k127_6048498_0 pfam abc-1 K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 582.0
PYH1_k127_6048498_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 346.0
PYH1_k127_6048498_11 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.0000001087 60.0
PYH1_k127_6048498_12 membrane transporter protein K07090 - - 0.0008836 48.0
PYH1_k127_6048498_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 349.0
PYH1_k127_6048498_3 Psort location Cytoplasmic, score K09707 - - 0.000000000000000000000000000000000000000007324 158.0
PYH1_k127_6048498_4 amino acid - - - 0.000000000000000000000000000000000000002716 163.0
PYH1_k127_6048498_5 DoxX - - - 0.00000000000000000000000000000001788 132.0
PYH1_k127_6048498_6 Rhodanese Homology Domain - - - 0.000000000000000000000002883 115.0
PYH1_k127_6048498_7 antisigma factor binding - - - 0.000000000000000000000005645 112.0
PYH1_k127_6048498_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000753 83.0
PYH1_k127_6048498_9 - - - - 0.000000000004099 75.0
PYH1_k127_6070456_0 Diadenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000005341 225.0
PYH1_k127_6070456_1 - - - - 0.000000000000000000000000000000000000000000000000319 186.0
PYH1_k127_6135851_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.408e-224 707.0
PYH1_k127_6135851_1 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 590.0
PYH1_k127_6135851_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 477.0
PYH1_k127_6135851_3 type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 397.0
PYH1_k127_6135851_4 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 350.0
PYH1_k127_6135851_5 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000001641 172.0
PYH1_k127_6135851_6 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000003725 160.0
PYH1_k127_6135851_7 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000002653 126.0
PYH1_k127_6138719_0 Phosphate acyltransferases K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 559.0
PYH1_k127_6138719_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003119 270.0
PYH1_k127_6138719_2 membrane K08978 - - 0.0000000000000000000000000000000000000000001519 162.0
PYH1_k127_6138719_3 Proteasome subunit K07395 - - 0.00003188 47.0
PYH1_k127_6158653_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 492.0
PYH1_k127_6158653_1 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 419.0
PYH1_k127_6158653_2 Universal stress protein family - - - 0.000000003351 58.0
PYH1_k127_6158653_3 - - - - 0.0000008977 53.0
PYH1_k127_6163145_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 478.0
PYH1_k127_6163145_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 457.0
PYH1_k127_6163145_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001008 251.0
PYH1_k127_6163145_3 PIN domain - - - 0.0000000000000000000000000000000000004194 144.0
PYH1_k127_6163145_4 toxin-antitoxin pair type II binding K06284 - - 0.0000000000189 71.0
PYH1_k127_6183969_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K00174 - 1.2.7.11,1.2.7.3 2.679e-217 689.0
PYH1_k127_6183969_1 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005816 273.0
PYH1_k127_6183969_2 Desulfoferrodoxin, ferrous iron-binding K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000000000001535 220.0
PYH1_k127_6183969_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000009487 159.0
PYH1_k127_6183969_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000002278 55.0
PYH1_k127_6189508_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 459.0
PYH1_k127_6189508_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000002508 242.0
PYH1_k127_6189508_2 PFAM glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005111 233.0
PYH1_k127_6189508_3 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000001871 222.0
PYH1_k127_6189508_4 - - - - 0.000000000000000000000000000003096 122.0
PYH1_k127_6189508_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000004912 100.0
PYH1_k127_6192882_0 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 433.0
PYH1_k127_6192882_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000002653 201.0
PYH1_k127_6192882_2 GYD domain - - - 0.00000000000000000000000000001685 119.0
PYH1_k127_6192882_3 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000005217 64.0
PYH1_k127_6193695_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 596.0
PYH1_k127_6193695_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 591.0
PYH1_k127_6193695_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 484.0
PYH1_k127_6193695_3 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 343.0
PYH1_k127_6193695_4 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 313.0
PYH1_k127_6193695_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000003041 195.0
PYH1_k127_6193695_6 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000002571 152.0
PYH1_k127_6193695_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000002912 89.0
PYH1_k127_6193695_8 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000001025 87.0
PYH1_k127_6193695_9 Transposase DDE domain K07487 - - 0.00000001934 63.0
PYH1_k127_6200871_0 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
PYH1_k127_6200871_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001022 210.0
PYH1_k127_6217779_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.388e-204 653.0
PYH1_k127_6217779_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 451.0
PYH1_k127_6217779_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 334.0
PYH1_k127_6217779_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000003713 157.0
PYH1_k127_6217779_4 helix_turn_helix, Lux Regulon - - - 0.0000000000001066 70.0
PYH1_k127_6217779_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000002679 71.0
PYH1_k127_6217779_6 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000003275 76.0
PYH1_k127_6217779_7 domain, Protein K01181,K08300,K08301 - 3.1.26.12,3.2.1.8 0.000000000005164 75.0
PYH1_k127_622408_0 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000004548 169.0
PYH1_k127_622408_1 Universal stress protein family K06149 - - 0.000000000000000002557 87.0
PYH1_k127_6252311_0 PFAM Oligopeptide transporter OPT superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 426.0
PYH1_k127_6252311_1 - - - - 0.000000000000000000000000000000001702 139.0
PYH1_k127_6252311_2 Belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.0000000000000000000000027 109.0
PYH1_k127_6254673_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 598.0
PYH1_k127_6254673_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 389.0
PYH1_k127_6254673_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
PYH1_k127_6254673_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001974 235.0
PYH1_k127_6254673_4 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
PYH1_k127_6254673_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000004947 130.0
PYH1_k127_6262258_0 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 493.0
PYH1_k127_6262258_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
PYH1_k127_6262258_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 305.0
PYH1_k127_6262798_0 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 392.0
PYH1_k127_6262798_1 NADP transhydrogenase K00324 - 1.6.1.2 0.00000000000000000000000000009591 118.0
PYH1_k127_6262798_2 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000001393 112.0
PYH1_k127_6262798_3 Protein of unknown function, DUF255 - - - 0.0000001387 57.0
PYH1_k127_6266211_0 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 375.0
PYH1_k127_6266211_1 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004247 282.0
PYH1_k127_6266211_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
PYH1_k127_6266211_3 FHA domain - - - 0.0000000000008189 74.0
PYH1_k127_6266211_4 Forkhead associated domain - - - 0.00000000005485 70.0
PYH1_k127_626897_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.697e-210 664.0
PYH1_k127_626897_1 antitermination protein NusG K05785 - - 0.000000000000000000000000000000000000000000000000001298 190.0
PYH1_k127_626897_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000003041 93.0
PYH1_k127_626897_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000291 61.0
PYH1_k127_626897_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0003194 52.0
PYH1_k127_6320145_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000003018 213.0
PYH1_k127_6320145_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000008393 188.0
PYH1_k127_6320145_2 PFAM RimK domain protein ATP-grasp K05844 - - 0.00000000000000000000000000000000000000007986 162.0
PYH1_k127_6320145_3 AAA domain K07028 - - 0.00000000000001491 79.0
PYH1_k127_6320145_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000011 59.0
PYH1_k127_6320145_5 Putative regulatory protein - - - 0.000008012 50.0
PYH1_k127_6347637_0 ABC transporter, transmembrane region - - - 0.0 1024.0
PYH1_k127_6347637_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 386.0
PYH1_k127_6347637_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008232 267.0
PYH1_k127_6347637_3 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000843 134.0
PYH1_k127_6347637_4 transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000000000000000003871 128.0
PYH1_k127_6347637_5 anti-sigma regulatory factor, serine threonine protein kinase K04757 - 2.7.11.1 0.000000000000000000000000000006723 125.0
PYH1_k127_6369026_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 337.0
PYH1_k127_6369026_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 261.0
PYH1_k127_6369026_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000003768 210.0
PYH1_k127_6369026_3 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000000000000989 176.0
PYH1_k127_6369026_4 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000004332 178.0
PYH1_k127_6379292_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1128.0
PYH1_k127_6379292_1 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004215 256.0
PYH1_k127_6379292_2 permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000007459 229.0
PYH1_k127_6379292_3 PFAM AsmA family protein K07290 - - 0.00000000000000000000000000000000000000000000003632 185.0
PYH1_k127_6401637_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.731e-289 916.0
PYH1_k127_6401637_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 9.791e-276 865.0
PYH1_k127_6401637_10 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000008475 144.0
PYH1_k127_6401637_11 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003956 136.0
PYH1_k127_6401637_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000004168 126.0
PYH1_k127_6401637_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000007393 121.0
PYH1_k127_6401637_14 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000009254 103.0
PYH1_k127_6401637_15 Protein of unknown function (DUF448) - - - 0.0000000000001874 76.0
PYH1_k127_6401637_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 564.0
PYH1_k127_6401637_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 516.0
PYH1_k127_6401637_4 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 487.0
PYH1_k127_6401637_5 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 262.0
PYH1_k127_6401637_6 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000007774 263.0
PYH1_k127_6401637_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000004623 223.0
PYH1_k127_6401637_8 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000006629 181.0
PYH1_k127_6401637_9 - - - - 0.0000000000000000000000000000000000000000000004482 174.0
PYH1_k127_6424708_0 Phosphoribosyl-ATP pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000005858 196.0
PYH1_k127_6424708_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000004578 174.0
PYH1_k127_6424708_2 PFAM Colicin V production protein K03558 - - 0.00000000000000000000001029 108.0
PYH1_k127_6424708_3 - - - - 0.0000000000001353 78.0
PYH1_k127_644996_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001591 272.0
PYH1_k127_644996_1 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000004872 216.0
PYH1_k127_644996_2 Protein of unknown function (DUF721) - - - 0.0000000001037 68.0
PYH1_k127_647421_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 2.667e-211 674.0
PYH1_k127_647421_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 349.0
PYH1_k127_647421_2 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000004215 200.0
PYH1_k127_647421_3 WbqC-like protein family - - - 0.00000000000000000000000000000004628 127.0
PYH1_k127_647421_4 PIN domain - - - 0.0000000000000000000000000003962 117.0
PYH1_k127_647421_5 positive regulation of growth - - - 0.000000000006984 68.0
PYH1_k127_6489884_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 550.0
PYH1_k127_6489884_1 ABC transporter K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 403.0
PYH1_k127_6489884_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 299.0
PYH1_k127_6489884_3 ThiW protein K16786,K16787 - - 0.0000000000000000000000000000000000000000001125 164.0
PYH1_k127_6489884_4 Cobalt transport protein K16785 - - 0.00000000000000000000000000008717 126.0
PYH1_k127_6489884_5 iron-sulfur binding K00184 - - 0.00000000001409 64.0
PYH1_k127_6508243_0 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 526.0
PYH1_k127_6508243_1 Yip1 domain - - - 0.000000000000000000000000000000000000000000007763 169.0
PYH1_k127_6508243_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.00000000000000000000000000000000000000006105 155.0
PYH1_k127_6508243_3 3D domain protein - - - 0.00000000000000000000000000000004421 131.0
PYH1_k127_6508243_4 - - - - 0.0000000000000000000000000000007505 125.0
PYH1_k127_6508243_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000003493 122.0
PYH1_k127_6508243_6 - - - - 0.0000000000000000000006636 96.0
PYH1_k127_6508243_7 Diguanylate cyclase K21084 - 2.7.7.65 0.0000001347 57.0
PYH1_k127_6513370_0 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000002371 241.0
PYH1_k127_6513370_1 Belongs to the ompA family K03640 - - 0.000006962 53.0
PYH1_k127_6516383_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.005e-262 822.0
PYH1_k127_6516383_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 544.0
PYH1_k127_6516383_2 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 529.0
PYH1_k127_6516383_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 458.0
PYH1_k127_6516383_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 387.0
PYH1_k127_6516383_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
PYH1_k127_6516383_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000001769 177.0
PYH1_k127_6525458_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
PYH1_k127_6525458_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000005805 103.0
PYH1_k127_6525458_2 Transposase IS200 like - - - 0.00000000000000000208 94.0
PYH1_k127_6568730_0 Fad linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 552.0
PYH1_k127_6568730_1 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
PYH1_k127_6568730_2 UbiA prenyltransferase family - - - 0.00000000000000000000000001143 116.0
PYH1_k127_6568730_3 dehydrogenase - - - 0.000000000000000009585 88.0
PYH1_k127_657567_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 529.0
PYH1_k127_657567_1 MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006064 249.0
PYH1_k127_6595536_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 509.0
PYH1_k127_6595536_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000003081 202.0
PYH1_k127_6595536_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000009613 165.0
PYH1_k127_6595536_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000006109 78.0
PYH1_k127_659655_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.059e-286 895.0
PYH1_k127_659655_1 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000001745 153.0
PYH1_k127_6622119_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 365.0
PYH1_k127_6622119_1 PDZ domain (Also known as DHR or GLGF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001694 280.0
PYH1_k127_6631862_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 394.0
PYH1_k127_6631862_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
PYH1_k127_6631862_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000008151 171.0
PYH1_k127_6631862_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000004981 113.0
PYH1_k127_6653884_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 9.61e-203 647.0
PYH1_k127_6653884_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
PYH1_k127_6653884_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000002235 208.0
PYH1_k127_6653884_3 Phosphocarrier protein HPr K08485,K11189 - - 0.00000000000000000000004446 102.0
PYH1_k127_6653884_4 Putative addiction module component - - - 0.000000000000001465 78.0
PYH1_k127_6653884_5 Belongs to the UPF0102 family K07460 - - 0.000001052 51.0
PYH1_k127_6663783_0 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 340.0
PYH1_k127_6663783_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 308.0
PYH1_k127_6663783_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000005429 238.0
PYH1_k127_6663783_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000443 235.0
PYH1_k127_6663783_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000004115 170.0
PYH1_k127_6663783_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000001532 119.0
PYH1_k127_6663783_6 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000001768 103.0
PYH1_k127_6669726_0 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000004794 198.0
PYH1_k127_6669726_1 Thioredoxin domain - - - 0.000000000000000000000000000000000002367 143.0
PYH1_k127_6669726_2 Redox-active disulfide protein - - - 0.00000000000000000000007504 104.0
PYH1_k127_6669726_3 Predicted permease K07089 - - 0.00001304 49.0
PYH1_k127_6674957_0 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000002364 151.0
PYH1_k127_6674957_1 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000003321 121.0
PYH1_k127_6674957_2 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000005488 96.0
PYH1_k127_6674957_3 - - - - 0.0000000004321 62.0
PYH1_k127_6695938_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 569.0
PYH1_k127_6695938_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 287.0
PYH1_k127_6695938_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000002418 151.0
PYH1_k127_6695938_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000003105 152.0
PYH1_k127_6695938_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000006901 119.0
PYH1_k127_6695938_5 COG0456 Acetyltransferases K03789 - 2.3.1.128 0.0000000000002144 78.0
PYH1_k127_6711684_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 3.358e-298 921.0
PYH1_k127_6711684_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 1.499e-209 658.0
PYH1_k127_6711684_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000003801 139.0
PYH1_k127_6711684_11 - - - - 0.000000000000006163 78.0
PYH1_k127_6711684_12 - - - - 0.0000000002631 63.0
PYH1_k127_6711684_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 617.0
PYH1_k127_6711684_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 492.0
PYH1_k127_6711684_4 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 434.0
PYH1_k127_6711684_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 395.0
PYH1_k127_6711684_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 338.0
PYH1_k127_6711684_7 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001445 220.0
PYH1_k127_6711684_8 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000006401 218.0
PYH1_k127_6711684_9 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000006941 159.0
PYH1_k127_6714868_0 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 304.0
PYH1_k127_6714868_1 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000001262 123.0
PYH1_k127_6714868_2 peptidyl-tyrosine sulfation - - - 0.00000000000129 77.0
PYH1_k127_6714868_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000004006 56.0
PYH1_k127_6714868_4 Putative zinc- or iron-chelating domain K06940 - - 0.0002532 48.0
PYH1_k127_6734043_0 PFAM major facilitator superfamily MFS_1 K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 501.0
PYH1_k127_6734043_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 361.0
PYH1_k127_6734043_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 355.0
PYH1_k127_6734043_3 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000004003 165.0
PYH1_k127_6734043_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000002411 153.0
PYH1_k127_6734043_5 Peptidyl-prolyl cis-trans isomerase K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042026,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000003176 102.0
PYH1_k127_6734043_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000008614 91.0
PYH1_k127_6734043_7 Pilus assembly protein, PilP K02664,K02665 - - 0.00000000000000001193 85.0
PYH1_k127_6739271_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 5.681e-282 883.0
PYH1_k127_6739271_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 3.293e-206 651.0
PYH1_k127_6750521_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 464.0
PYH1_k127_6750521_1 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 323.0
PYH1_k127_6750521_2 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002936 113.0
PYH1_k127_6750521_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000003326 90.0
PYH1_k127_6755772_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.54e-198 624.0
PYH1_k127_6755772_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000593 140.0
PYH1_k127_6755772_2 Haemolytic - - - 0.0000000000000000000158 96.0
PYH1_k127_6778851_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 362.0
PYH1_k127_6778851_1 PFAM Extracellular solute-binding protein, family 3 K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 342.0
PYH1_k127_6778851_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 310.0
PYH1_k127_6778851_3 Outer membrane lipoprotein - - - 0.0000000000000000000003416 106.0
PYH1_k127_6778851_4 Lysin motif - - - 0.000000000000000000001433 108.0
PYH1_k127_6778851_5 Protein of unknown function (DUF721) - - - 0.00000000005406 69.0
PYH1_k127_6814606_0 PFAM Enoyl-CoA hydratase isomerase K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 550.0
PYH1_k127_6814606_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 447.0
PYH1_k127_6814606_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 437.0
PYH1_k127_6814606_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
PYH1_k127_6814606_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 330.0
PYH1_k127_6814606_5 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 325.0
PYH1_k127_6814606_6 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000461 209.0
PYH1_k127_6825260_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.678e-231 734.0
PYH1_k127_6825260_1 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 463.0
PYH1_k127_6825260_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 394.0
PYH1_k127_6825260_3 Yqey-like protein K09117 - - 0.0000000000000000000000000000000004128 138.0
PYH1_k127_6825260_4 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000001887 136.0
PYH1_k127_6825260_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000002298 88.0
PYH1_k127_6825260_6 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000009435 75.0
PYH1_k127_6840412_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1487.0
PYH1_k127_6840412_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 303.0
PYH1_k127_6843257_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.113e-209 659.0
PYH1_k127_6843257_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 591.0
PYH1_k127_6843257_10 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 361.0
PYH1_k127_6843257_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 333.0
PYH1_k127_6843257_12 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 314.0
PYH1_k127_6843257_13 YceG-like family K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 305.0
PYH1_k127_6843257_14 RimK domain protein ATP-grasp K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004353 278.0
PYH1_k127_6843257_15 Conserved protein K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002633 278.0
PYH1_k127_6843257_16 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000197 237.0
PYH1_k127_6843257_17 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000000000000105 188.0
PYH1_k127_6843257_18 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000001383 163.0
PYH1_k127_6843257_19 Essential cell division protein K03589 - - 0.000000000000000000001437 106.0
PYH1_k127_6843257_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 573.0
PYH1_k127_6843257_20 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000005627 69.0
PYH1_k127_6843257_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 545.0
PYH1_k127_6843257_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 512.0
PYH1_k127_6843257_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 459.0
PYH1_k127_6843257_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 447.0
PYH1_k127_6843257_7 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 422.0
PYH1_k127_6843257_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 406.0
PYH1_k127_6843257_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 387.0
PYH1_k127_6847710_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 527.0
PYH1_k127_6847710_1 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 479.0
PYH1_k127_6847710_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001014 254.0
PYH1_k127_6847710_3 Sh3 type 3 domain protein - - - 0.000000000000000000005188 104.0
PYH1_k127_68848_0 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 319.0
PYH1_k127_68848_1 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000937 270.0
PYH1_k127_68848_2 - - - - 0.000001894 53.0
PYH1_k127_6901771_0 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 1.493e-307 949.0
PYH1_k127_6901771_1 ABC transporter K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 297.0
PYH1_k127_6947974_0 Oligopeptidase F K08602 - - 6.357e-198 634.0
PYH1_k127_6947974_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 369.0
PYH1_k127_6947974_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 342.0
PYH1_k127_6947974_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003499 245.0
PYH1_k127_6947974_4 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000001281 181.0
PYH1_k127_6947974_5 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000001835 177.0
PYH1_k127_6947974_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000004464 168.0
PYH1_k127_6947974_7 - - - - 0.000000000000000000000000000000000009024 145.0
PYH1_k127_6957061_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0 1019.0
PYH1_k127_6957061_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 531.0
PYH1_k127_6957061_2 acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 412.0
PYH1_k127_6957061_4 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000003868 70.0
PYH1_k127_6981492_0 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 415.0
PYH1_k127_6981492_1 Psort location Cytoplasmic, score - - - 0.0000000000000002439 92.0
PYH1_k127_6981492_2 - - - - 0.0000000003881 66.0
PYH1_k127_6990581_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 3.274e-217 691.0
PYH1_k127_6990581_1 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 542.0
PYH1_k127_6990581_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 493.0
PYH1_k127_6990581_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000003671 165.0
PYH1_k127_702485_0 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000433 170.0
PYH1_k127_702485_1 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000002886 147.0
PYH1_k127_702485_2 - - - - 0.000000000000000000000000000000009162 133.0
PYH1_k127_702485_3 - - - - 0.00006289 46.0
PYH1_k127_7025759_0 aminopeptidase N K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 568.0
PYH1_k127_7025759_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 397.0
PYH1_k127_7025759_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000004814 173.0
PYH1_k127_7025759_4 SH3 domain K07184 - - 0.00000000000000000002057 100.0
PYH1_k127_7039988_0 ABC transporter K02028,K09972,K10004,K10038 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 358.0
PYH1_k127_7039988_1 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 274.0
PYH1_k127_7039988_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006852 257.0
PYH1_k127_7039988_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.0000000000000000000000000000000000000000000000000000000001079 221.0
PYH1_k127_7046329_0 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 406.0
PYH1_k127_7046329_1 His Kinase A (phosphoacceptor) domain K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 373.0
PYH1_k127_7051727_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 475.0
PYH1_k127_7051727_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 431.0
PYH1_k127_7051727_2 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 302.0
PYH1_k127_7051727_3 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.000002725 49.0
PYH1_k127_7067303_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.343e-264 829.0
PYH1_k127_7067303_1 Exopolysaccharide biosynthesis protein YbjH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 397.0
PYH1_k127_7067303_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 344.0
PYH1_k127_7067303_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 295.0
PYH1_k127_7067303_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000004753 132.0
PYH1_k127_7067303_5 PFAM nitrogen-fixing NifU - - - 0.00000000000000000000000002946 109.0
PYH1_k127_7067303_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000001196 81.0
PYH1_k127_7067303_7 Peptidase family M23 - - - 0.00001401 47.0
PYH1_k127_7067303_8 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0001071 44.0
PYH1_k127_7070076_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 5.249e-233 728.0
PYH1_k127_7070076_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 466.0
PYH1_k127_7070076_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 398.0
PYH1_k127_7070076_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000001948 77.0
PYH1_k127_7070076_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000001283 53.0
PYH1_k127_7070076_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000002935 51.0
PYH1_k127_7081880_0 50S ribosome-binding GTPase - - - 0.0000000000000000000000000000000000000000004859 177.0
PYH1_k127_7081880_1 50S ribosome-binding GTPase - - - 0.0000000000000000000000000000000003849 150.0
PYH1_k127_7081880_2 - - - - 0.000000000000000000000001949 108.0
PYH1_k127_7081880_3 PFAM SH3 type 3 K07184 - - 0.00000000005182 72.0
PYH1_k127_7081880_4 - - - - 0.0000002415 57.0
PYH1_k127_708831_0 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 389.0
PYH1_k127_708831_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 364.0
PYH1_k127_708831_2 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000008173 126.0
PYH1_k127_708831_3 Protein of unknown function (DUF4197) - - - 0.00000000000000000000172 94.0
PYH1_k127_7126922_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 604.0
PYH1_k127_7126922_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000003432 164.0
PYH1_k127_7126922_2 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000988 137.0
PYH1_k127_7126922_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000005592 73.0
PYH1_k127_7137446_0 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 298.0
PYH1_k127_7137446_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000003969 228.0
PYH1_k127_7137446_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000007458 188.0
PYH1_k127_7137446_3 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000005421 181.0
PYH1_k127_7137446_4 glycine betaine K02000 - 3.6.3.32 0.00000000000000000001489 101.0
PYH1_k127_7137446_6 TPR repeat-containing protein - - - 0.0001791 51.0
PYH1_k127_7165575_0 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 541.0
PYH1_k127_7165575_1 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 533.0
PYH1_k127_7165575_2 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 452.0
PYH1_k127_7201939_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 613.0
PYH1_k127_7201939_1 IMG reference gene - - - 0.00000000000004131 74.0
PYH1_k127_7203156_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
PYH1_k127_7203156_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000001152 213.0
PYH1_k127_7203156_2 metal ion binding - - - 0.00000133 54.0
PYH1_k127_7203156_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000005418 57.0
PYH1_k127_7203156_4 Belongs to the peptidase S8 family K13735,K20276,K21449 - - 0.00001973 54.0
PYH1_k127_7213837_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.322e-202 636.0
PYH1_k127_7213837_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 557.0
PYH1_k127_7213837_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 535.0
PYH1_k127_7213837_3 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 359.0
PYH1_k127_7213837_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 306.0
PYH1_k127_7213837_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000002294 260.0
PYH1_k127_7213837_6 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000001138 222.0
PYH1_k127_7213837_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000003349 207.0
PYH1_k127_7213837_8 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000003045 123.0
PYH1_k127_7235286_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 574.0
PYH1_k127_7235286_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 467.0
PYH1_k127_7235286_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000876 147.0
PYH1_k127_7235286_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000003531 141.0
PYH1_k127_7235286_4 response regulator, receiver - - - 0.0000000000000000000000000003104 116.0
PYH1_k127_7235286_5 PFAM histidine kinase A domain protein - - - 0.000000000000000000000000003311 119.0
PYH1_k127_7235286_6 - - - - 0.000000000000000000002393 95.0
PYH1_k127_7236756_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000008665 163.0
PYH1_k127_7236756_1 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000000001138 154.0
PYH1_k127_7236756_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000001391 101.0
PYH1_k127_7236756_3 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.00000000000000006287 94.0
PYH1_k127_7248475_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 372.0
PYH1_k127_7248475_1 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 325.0
PYH1_k127_7248475_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000007199 129.0
PYH1_k127_7248475_3 Transposase and inactivated derivatives - - - 0.000000000000000000000000000004871 124.0
PYH1_k127_7248475_4 DNA polymerase type-B family K02336 - 2.7.7.7 0.000000000000000000003089 94.0
PYH1_k127_725577_0 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 364.0
PYH1_k127_725577_1 SMART Transcription regulator, AsnC-type - - - 0.00000000000000000000000000000000000000000000000001788 184.0
PYH1_k127_725577_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000003416 154.0
PYH1_k127_7280506_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.021e-260 807.0
PYH1_k127_7280506_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000005172 237.0
PYH1_k127_7280506_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000006528 175.0
PYH1_k127_7280506_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000001592 143.0
PYH1_k127_7286935_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.104e-300 931.0
PYH1_k127_7286935_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.12e-294 914.0
PYH1_k127_7286935_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 584.0
PYH1_k127_7286935_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000001466 141.0
PYH1_k127_7296700_0 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 523.0
PYH1_k127_7296700_1 Domain of unknown function (DUF4833) - - - 0.0000000000000007544 85.0
PYH1_k127_7316826_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 5.102e-206 670.0
PYH1_k127_7316826_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 422.0
PYH1_k127_7316826_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 308.0
PYH1_k127_7316826_3 amidohydrolase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004848 280.0
PYH1_k127_7316826_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004001 275.0
PYH1_k127_7326314_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000006341 207.0
PYH1_k127_7326314_1 Type II/IV secretion system protein K02454,K02652 - - 0.000000000000000003852 86.0
PYH1_k127_7326314_2 ABC-type uncharacterized transport system - - - 0.000000000002137 79.0
PYH1_k127_7326314_3 Type II transport protein GspH K08084 - - 0.00000000002691 72.0
PYH1_k127_7326314_4 domain protein - - - 0.00001387 57.0
PYH1_k127_7333240_0 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 423.0
PYH1_k127_7333240_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002324 128.0
PYH1_k127_7333240_2 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000004165 109.0
PYH1_k127_7362280_0 Heat shock 70 kDa protein K04043 - - 1.646e-200 631.0
PYH1_k127_7362280_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 551.0
PYH1_k127_7362280_2 Periplasmic binding protein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 301.0
PYH1_k127_7362280_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000002694 110.0
PYH1_k127_7411007_0 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 559.0
PYH1_k127_7411007_1 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 487.0
PYH1_k127_7411007_2 Xylose isomerase-like TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 351.0
PYH1_k127_7411007_4 Metal binding domain of Ada K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000009625 198.0
PYH1_k127_7411007_5 - - - - 0.000000000000000000000000000000000000000004738 160.0
PYH1_k127_7443495_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0 1347.0
PYH1_k127_7443495_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 391.0
PYH1_k127_7443495_2 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00005272 48.0
PYH1_k127_7447679_0 SPTR N-acetylneuraminic acid synthase, N-terminal domain protein K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 500.0
PYH1_k127_7447679_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 349.0
PYH1_k127_7447679_2 Belongs to the aldehyde dehydrogenase family K00128,K00135,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000001301 222.0
PYH1_k127_7447679_3 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.00000000000000007253 93.0
PYH1_k127_7447679_4 Cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000008557 78.0
PYH1_k127_7454344_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 601.0
PYH1_k127_7454344_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000001218 214.0
PYH1_k127_7454344_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000001313 128.0
PYH1_k127_7473203_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004255 273.0
PYH1_k127_7473203_1 - - - - 0.0000000000000000000000000000005432 127.0
PYH1_k127_7473203_2 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000004242 120.0
PYH1_k127_7473203_3 acetyltransferase K01246 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 0.00000000001254 71.0
PYH1_k127_7567932_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 490.0
PYH1_k127_7567932_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000001959 174.0
PYH1_k127_7567932_3 Protein of unknown function (DUF2905) - - - 0.0000004075 55.0
PYH1_k127_7589971_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 481.0
PYH1_k127_7589971_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 317.0
PYH1_k127_7589971_10 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00003087 57.0
PYH1_k127_7589971_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 318.0
PYH1_k127_7589971_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 304.0
PYH1_k127_7589971_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003104 213.0
PYH1_k127_7589971_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007225 206.0
PYH1_k127_7589971_6 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000899 174.0
PYH1_k127_7589971_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000004244 137.0
PYH1_k127_7589971_8 TPR repeat - - - 0.00000000000000009509 94.0
PYH1_k127_7589971_9 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000006973 72.0
PYH1_k127_7593423_0 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 294.0
PYH1_k127_7593423_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000003814 177.0
PYH1_k127_7593423_2 - - - - 0.000000000000000000001828 100.0
PYH1_k127_7603418_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.331e-200 629.0
PYH1_k127_7603418_1 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 392.0
PYH1_k127_7603418_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000008582 227.0
PYH1_k127_7603418_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000002484 149.0
PYH1_k127_7643604_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 411.0
PYH1_k127_7643604_2 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 338.0
PYH1_k127_7643604_3 Forkhead associated domain - - - 0.000000005189 67.0
PYH1_k127_7643604_4 Transposase DDE domain K07495 - - 0.0001409 46.0
PYH1_k127_7657316_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 5.111e-203 651.0
PYH1_k127_7657316_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 2.602e-200 642.0
PYH1_k127_7657316_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 368.0
PYH1_k127_7657316_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
PYH1_k127_7657316_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
PYH1_k127_7657316_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000001041 182.0
PYH1_k127_7657316_6 PFAM Outer membrane K06142 - - 0.00003922 47.0
PYH1_k127_769799_0 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000002062 255.0
PYH1_k127_769799_1 peptidase M24 - - - 0.0000000000000000000000000000000001125 137.0
PYH1_k127_769799_2 PFAM peptidase M24 - - - 0.000000000000000000000000000001104 127.0
PYH1_k127_769799_3 PFAM Cold-shock K03704 - - 0.00000000000000000000000002864 108.0
PYH1_k127_7712726_0 Conserved hypothetical protein 698 - - - 1.514e-229 721.0
PYH1_k127_7712726_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002531 271.0
PYH1_k127_7717205_0 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 4.062e-240 746.0
PYH1_k127_7717205_1 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 4.031e-200 627.0
PYH1_k127_7717205_10 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000009249 145.0
PYH1_k127_7717205_11 - - - - 0.0000000000000000000000000000000002359 134.0
PYH1_k127_7717205_12 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000000103 131.0
PYH1_k127_7717205_13 PFAM Dissimilatory sulfite reductase D - - - 0.000000000000000000000000000006516 120.0
PYH1_k127_7717205_14 - - - - 0.000000000000000000008631 93.0
PYH1_k127_7717205_15 - - - - 0.00000000000000001333 89.0
PYH1_k127_7717205_16 DNA-binding transcriptional activator of the SARP family - - - 0.000000000003113 76.0
PYH1_k127_7717205_17 Poly A polymerase, head domain K00970 - 2.7.7.19 0.000000002195 64.0
PYH1_k127_7717205_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 548.0
PYH1_k127_7717205_3 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 524.0
PYH1_k127_7717205_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 365.0
PYH1_k127_7717205_5 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 309.0
PYH1_k127_7717205_6 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 292.0
PYH1_k127_7717205_7 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003943 267.0
PYH1_k127_7717205_8 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001527 195.0
PYH1_k127_7717205_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000005091 147.0
PYH1_k127_7718550_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 7.365e-223 736.0
PYH1_k127_7718550_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 565.0
PYH1_k127_7718550_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 492.0
PYH1_k127_7718550_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 372.0
PYH1_k127_7718550_4 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 328.0
PYH1_k127_7718550_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000001965 190.0
PYH1_k127_7718550_6 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000007582 179.0
PYH1_k127_7718550_7 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000004325 183.0
PYH1_k127_7718550_8 Domain of unknown function (DUF3786) - - - 0.000000000003019 67.0
PYH1_k127_7742320_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007196 267.0
PYH1_k127_7742320_1 Belongs to the 'phage' integrase family K14059 - - 0.00000000000000000000000000000000000000002874 166.0
PYH1_k127_7748334_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.26e-204 649.0
PYH1_k127_7748334_1 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 404.0
PYH1_k127_7748334_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 409.0
PYH1_k127_7748334_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 287.0
PYH1_k127_7750042_0 phosphoribosyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 256.0
PYH1_k127_7750042_1 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000003626 232.0
PYH1_k127_7750042_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000000001649 151.0
PYH1_k127_7750042_3 AhpC/TSA family - - - 0.000000000000000000000000000005019 120.0
PYH1_k127_7750042_4 Sulfate permease family K03321 - - 0.000000000000000000005705 95.0
PYH1_k127_7750042_5 AhpC/TSA family - - - 0.00000000003788 67.0
PYH1_k127_7750042_6 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000006405 61.0
PYH1_k127_7769034_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 497.0
PYH1_k127_7769034_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000002886 173.0
PYH1_k127_7769034_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K11392 - 2.1.1.178 0.000000000000000000000000000000000000001543 156.0
PYH1_k127_7769034_3 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000007305 143.0
PYH1_k127_7769034_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K11392 - 2.1.1.178 0.0000000000000000000000002169 108.0
PYH1_k127_7769034_5 Putative regulatory protein - - - 0.00000000000000000000001102 104.0
PYH1_k127_7769034_6 - - - - 0.0000000000004592 72.0
PYH1_k127_7769034_7 - - - - 0.00000001928 60.0
PYH1_k127_7781733_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 557.0
PYH1_k127_7781733_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002532 189.0
PYH1_k127_7781733_2 Formate/nitrite transporter K06212,K21993 - - 0.00000000000000000000000000000000000000000008633 161.0
PYH1_k127_7793769_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 564.0
PYH1_k127_7793769_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 460.0
PYH1_k127_7793769_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 400.0
PYH1_k127_7793769_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000004545 178.0
PYH1_k127_7798089_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 3.113e-235 742.0
PYH1_k127_7798089_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 488.0
PYH1_k127_7798089_10 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000252 239.0
PYH1_k127_7798089_11 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000003157 217.0
PYH1_k127_7798089_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 479.0
PYH1_k127_7798089_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 439.0
PYH1_k127_7798089_4 Binding-protein-dependent transport system inner membrane component K02033,K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 426.0
PYH1_k127_7798089_5 Binding-protein-dependent transport system inner membrane component K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 401.0
PYH1_k127_7798089_6 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 407.0
PYH1_k127_7798089_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002181 257.0
PYH1_k127_7798089_8 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000001641 263.0
PYH1_k127_7798089_9 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488,K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005509 246.0
PYH1_k127_7819929_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1033.0
PYH1_k127_7819929_1 Hydrolases of the alpha beta superfamily K06889,K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000003655 233.0
PYH1_k127_783101_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0 1044.0
PYH1_k127_783101_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 2.297e-199 632.0
PYH1_k127_783101_2 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 326.0
PYH1_k127_783101_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002615 263.0
PYH1_k127_783101_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616 - 2.2.1.1,2.2.1.2 0.00000000000000000000000000000000000202 139.0
PYH1_k127_7837201_0 elongation factor Tu domain 2 protein K02355 - - 1.05e-245 780.0
PYH1_k127_7837201_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001724 287.0
PYH1_k127_7837201_2 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000001606 212.0
PYH1_k127_7837201_3 - - - - 0.00000000000000000000000000001114 124.0
PYH1_k127_7912068_0 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 591.0
PYH1_k127_7912068_1 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 544.0
PYH1_k127_7912068_2 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 492.0
PYH1_k127_7912068_3 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001008 246.0
PYH1_k127_7912068_4 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000001895 177.0
PYH1_k127_7912068_5 zinc-ribbon domain - - - 0.0000000000000000000000000000000000009774 157.0
PYH1_k127_7912068_6 - - - - 0.000000001405 61.0
PYH1_k127_7912068_7 - - - - 0.0003037 48.0
PYH1_k127_79350_0 DNA polymerase A domain K02335 - 2.7.7.7 2.072e-261 833.0
PYH1_k127_79350_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 3.769e-232 745.0
PYH1_k127_79350_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 2.572e-199 633.0
PYH1_k127_79350_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 401.0
PYH1_k127_79350_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000007292 255.0
PYH1_k127_79350_5 - - - - 0.000000000000000000000000000000000000000007061 159.0
PYH1_k127_79350_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003171 138.0
PYH1_k127_79350_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000001146 127.0
PYH1_k127_79350_8 - - - - 0.00000000000000000002316 93.0
PYH1_k127_79350_9 Transposase K07483 - - 0.0004452 52.0
PYH1_k127_7937838_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 367.0
PYH1_k127_7937838_1 chain release factor K15034 - - 0.000000000000000000000000000000002062 132.0
PYH1_k127_7939080_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
PYH1_k127_7939080_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001514 251.0
PYH1_k127_7939080_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000003288 229.0
PYH1_k127_7939080_3 MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000000003787 203.0
PYH1_k127_7944521_0 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 349.0
PYH1_k127_7944521_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001043 285.0
PYH1_k127_7944521_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000001678 192.0
PYH1_k127_7944521_3 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000002777 177.0
PYH1_k127_7948052_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 1.969e-202 648.0
PYH1_k127_7948052_1 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000006017 209.0
PYH1_k127_7948052_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000001461 175.0
PYH1_k127_7948052_3 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000001328 167.0
PYH1_k127_7953103_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 471.0
PYH1_k127_7953103_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 407.0
PYH1_k127_7953103_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 301.0
PYH1_k127_7953103_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 298.0
PYH1_k127_7953103_4 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000002578 162.0
PYH1_k127_7953103_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000002258 110.0
PYH1_k127_7965264_0 Histidine kinase K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 376.0
PYH1_k127_7965264_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001383 234.0
PYH1_k127_7965264_2 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000001392 146.0
PYH1_k127_7965264_3 - - - - 0.0000000000000000026 85.0
PYH1_k127_7973419_0 Bacterial regulatory protein, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 362.0
PYH1_k127_7973419_1 GAF domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000004381 273.0
PYH1_k127_7973419_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000001358 178.0
PYH1_k127_7973419_3 diguanylate cyclase - - - 0.00000000000000000001461 108.0
PYH1_k127_7973842_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 385.0
PYH1_k127_7973842_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 362.0
PYH1_k127_7990464_0 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 444.0
PYH1_k127_7990464_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - 0.000000000000000000000000000000000000000000000000003323 192.0
PYH1_k127_7990464_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000002028 203.0
PYH1_k127_7990464_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000003385 94.0
PYH1_k127_7990464_4 COGs COG0835 Chemotaxis signal transduction protein K03408 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009605,GO:0009893,GO:0009987,GO:0010604,GO:0016020,GO:0019222,GO:0019904,GO:0023052,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0032991,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0098561,GO:1901873,GO:1901875 - 0.00000000000000001065 90.0
PYH1_k127_8001167_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 391.0
PYH1_k127_8001167_1 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 313.0
PYH1_k127_8001167_2 ABC transporter K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 295.0
PYH1_k127_8001167_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000002458 128.0
PYH1_k127_8004025_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 479.0
PYH1_k127_8004790_0 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 502.0
PYH1_k127_8004790_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 298.0
PYH1_k127_8004790_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005318 258.0
PYH1_k127_8004790_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000007681 191.0
PYH1_k127_8004790_4 PFAM peptidase K21471 - - 0.000000000000000000000000000000000000000003833 174.0
PYH1_k127_8004790_5 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000002247 53.0
PYH1_k127_8022510_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 576.0
PYH1_k127_8022510_1 Signal transduction histidine kinase, nitrogen specific - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
PYH1_k127_8022510_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000549 165.0
PYH1_k127_8022510_3 Tetratricopeptide repeat - - - 0.000000008829 64.0
PYH1_k127_8037656_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 602.0
PYH1_k127_8037656_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 451.0
PYH1_k127_8059592_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 573.0
PYH1_k127_8059592_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 554.0
PYH1_k127_8059592_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 362.0
PYH1_k127_8059592_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000003183 151.0
PYH1_k127_8063790_0 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 503.0
PYH1_k127_8063790_1 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000664 280.0
PYH1_k127_8063790_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000264 206.0
PYH1_k127_8063790_3 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000004026 192.0
PYH1_k127_8063790_4 CBS domain - - - 0.000001126 57.0
PYH1_k127_8063790_5 positive regulation of growth rate - - - 0.000009603 54.0
PYH1_k127_8075576_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 306.0
PYH1_k127_8075576_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000002603 202.0
PYH1_k127_8075576_2 PFAM Methyl-accepting chemotaxis protein (MCP) K03406 - - 0.00000000000000000000000000000001052 147.0
PYH1_k127_8075576_3 PFAM VanZ - - - 0.00000000000000000003639 95.0
PYH1_k127_8075576_4 PIN domain - - - 0.0000000002422 65.0
PYH1_k127_8077190_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 403.0
PYH1_k127_8077190_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000009154 233.0
PYH1_k127_8077190_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000002058 205.0
PYH1_k127_8077190_3 PFAM cytochrome c assembly protein - - - 0.0006809 48.0
PYH1_k127_8143922_0 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 530.0
PYH1_k127_8143922_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000002482 175.0
PYH1_k127_8143922_2 malto-oligosyltrehalose synthase K06044 - 5.4.99.15 0.0000000000000000000000000000000000000001505 154.0
PYH1_k127_8171168_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003698 285.0
PYH1_k127_8171168_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000005834 83.0
PYH1_k127_8189464_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 419.0
PYH1_k127_8189464_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 344.0
PYH1_k127_8189464_2 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
PYH1_k127_8189464_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000631 219.0
PYH1_k127_8189464_4 - - - - 0.0000000000000000000000000000000000000007557 158.0
PYH1_k127_8189464_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000017 84.0
PYH1_k127_8189464_6 PFAM regulatory protein AsnC Lrp family - - - 0.0000000004153 63.0
PYH1_k127_8191413_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1258.0
PYH1_k127_8191413_1 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 320.0
PYH1_k127_8191413_2 molybdopterin oxidoreductase Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004359 265.0
PYH1_k127_8191413_3 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000009933 151.0
PYH1_k127_8238665_0 YicC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005482 241.0
PYH1_k127_8238665_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000004447 205.0
PYH1_k127_8238665_2 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000901 183.0
PYH1_k127_8238665_3 Belongs to the UPF0296 family K09777 - - 0.0000000000000000000000000000000001669 134.0
PYH1_k127_8238665_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000003015 58.0
PYH1_k127_827878_0 phosphorelay sensor kinase activity K01120,K01768,K02486,K11356,K11894,K11913 - 2.7.13.3,3.1.4.17,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 494.0
PYH1_k127_827878_1 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 400.0
PYH1_k127_827878_2 response regulator receiver K02658 - - 0.00000000000007882 76.0
PYH1_k127_827878_3 Bacterial SH3 domain K07184 - - 0.00000004149 62.0
PYH1_k127_827878_4 ABC-type multidrug transport system ATPase component - - - 0.00000008543 63.0
PYH1_k127_827878_5 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K21020 - 2.7.7.65 0.0000143 51.0
PYH1_k127_8283859_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
PYH1_k127_8283859_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 325.0
PYH1_k127_8283859_2 - - - - 0.0000000000000000000000000000000000008591 145.0
PYH1_k127_840439_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 345.0
PYH1_k127_840439_1 diguanylate cyclase - - - 0.000000000000000000003634 97.0
PYH1_k127_860001_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1059.0
PYH1_k127_860001_1 PFAM amidohydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 577.0
PYH1_k127_860001_2 TIGRFAM glutamate formiminotransferase K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 467.0
PYH1_k127_860001_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000004931 215.0
PYH1_k127_86488_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 571.0
PYH1_k127_86488_1 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 545.0
PYH1_k127_86488_2 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 466.0
PYH1_k127_86488_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001185 282.0
PYH1_k127_86488_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
PYH1_k127_86488_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000004852 194.0
PYH1_k127_86488_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000003291 162.0
PYH1_k127_86488_7 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000006808 130.0
PYH1_k127_86488_8 Tetratricopeptide repeat - - - 0.000000000000000000000001173 115.0
PYH1_k127_871706_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.16e-251 789.0
PYH1_k127_871706_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 488.0
PYH1_k127_882115_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 4.283e-275 856.0
PYH1_k127_882115_1 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 407.0
PYH1_k127_882115_2 PFAM ABC transporter K01996 - - 0.0000000000000000976 79.0
PYH1_k127_882115_3 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.000000000006471 72.0
PYH1_k127_893821_0 - - - - 2.176e-202 647.0
PYH1_k127_893821_1 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 489.0
PYH1_k127_893821_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 308.0
PYH1_k127_893821_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 299.0
PYH1_k127_893821_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000002957 251.0
PYH1_k127_893821_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000001182 190.0
PYH1_k127_893821_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000002285 156.0
PYH1_k127_893821_7 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.0000000000000000000000003485 112.0
PYH1_k127_893821_8 Acetyltransferase K03789 - 2.3.1.128 0.0000000000000000001424 94.0
PYH1_k127_893821_9 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0002045 45.0
PYH1_k127_89768_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 515.0
PYH1_k127_89768_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 377.0
PYH1_k127_89768_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000001319 135.0
PYH1_k127_89768_3 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000278 96.0
PYH1_k127_89768_4 - - - - 0.000000005114 58.0
PYH1_k127_898786_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 2.566e-205 646.0
PYH1_k127_967558_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 501.0
PYH1_k127_967558_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000003084 196.0
PYH1_k127_967558_2 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000001741 179.0
PYH1_k127_967558_3 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.0000000000000000000000000000000000000009978 153.0
PYH1_k127_967558_4 FAD binding domain K21401 - 1.3.99.38 0.000000000000000000000000000000001278 142.0
PYH1_k127_967558_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000006743 100.0
PYH1_k127_967558_6 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000002929 58.0
PYH1_k127_967558_7 - - - - 0.0000001373 56.0
PYH1_k127_982765_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000742 229.0
PYH1_k127_982765_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000056 151.0
PYH1_k127_982765_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000001285 143.0
PYH1_k127_992937_0 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 377.0
PYH1_k127_992937_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
PYH1_k127_992937_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005572 253.0
PYH1_k127_993991_0 - - - - 0.0 1102.0
PYH1_k127_993991_1 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000001455 207.0
PYH1_k127_993991_2 - - - - 0.000000000000000000000000000000000000000000000000000004984 198.0
PYH1_k127_993991_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000005685 179.0
PYH1_k127_993991_4 Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000007535 164.0